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Do you want to travel with La Santaniana?
On this page you will find all the information for your next trip with La Santaniana: best connections, destinations, payment methods, services provided and user reviews!
Most booked bus connections from La Santaniana
Ciudad del Este, PY
La Santaniana
4h 40m
0
5:15 PM
Capiatá
Bus Stop
9:55 PM
Ciudad del Este, PY
Km 7 Station
0
Premium Economy
$13
A Bus from La Santaniana goes from Bus Stop, Capiatá (Paraguay) at 1/8/2026 5:15:00 PM to Km 7 Station, Ciudad del Este, PY (Paraguay) arriving at 1/8/2026 9:55:00 PM. 50 Premium Economy ticket for $13 per person are available. Travel duration is 4h 40m
Buenos Aires
La Santaniana
19h 10m
0
12:30 PM
Asunción, PY
Bus Station Assunção
7:40 AM
Buenos Aires
Retiro Bus Station
0
Premium Economy
$111
A Bus from La Santaniana goes from Bus Station Assunção, Asunción, PY (Paraguay) at 1/15/2026 12:30:00 PM to Retiro Bus Station, Buenos Aires (Argentina) arriving at 1/16/2026 7:40:00 AM. 50 Premium Economy ticket for $111 per person are available. Travel duration is 19h 10m
Ciudad del Este, PY
La Santaniana
6h 15m
0
3:40 PM
Asunción, PY
Bus Station Assunção
9:55 PM
Ciudad del Este, PY
Km 7 Station
0
Premium Economy
$16
A Bus from La Santaniana goes from Bus Station Assunção, Asunción, PY (Paraguay) at 1/8/2026 3:40:00 PM to Km 7 Station, Ciudad del Este, PY (Paraguay) arriving at 1/8/2026 9:55:00 PM. 50 Premium Economy ticket for $16 per person are available. Travel duration is 6h 15m
Asunción, PY
La Santaniana
5h 45m
0
7:10 AM
Ciudad del Este, PY
Km 7 Station
12:55 PM
Asunción, PY
Bus Station Assunção
0
Premium Economy
$16
A Bus from La Santaniana goes from Km 7 Station, Ciudad del Este, PY (Paraguay) at 1/2/2026 7:10:00 AM to Bus Station Assunção, Asunción, PY (Paraguay) arriving at 1/2/2026 12:55:00 PM. 50 Premium Economy ticket for $16 per person are available. Travel duration is 5h 45m
Asunción, PY
La Santaniana
6h 20m
0
11:00 PM
Pedro Juan Caballero
Central Bus Station
5:20 AM
Asunción, PY
Bus Station Assunção
0
Premium Economy
$21
A Bus from La Santaniana goes from Central Bus Station, Pedro Juan Caballero (Paraguay) at 12/23/2025 11:00:00 PM to Bus Station Assunção, Asunción, PY (Paraguay) arriving at 12/24/2025 5:20:00 AM. 50 Premium Economy ticket for $21 per person are available. Travel duration is 6h 20m
Ciudad del Este, PY
La Santaniana
4h 10m
0
5:45 PM
Itauguá
Bus Stop
9:55 PM
Ciudad del Este, PY
Km 7 Station
0
Premium Economy
$13
A Bus from La Santaniana goes from Bus Stop, Itauguá (Paraguay) at 1/5/2026 5:45:00 PM to Km 7 Station, Ciudad del Este, PY (Paraguay) arriving at 1/5/2026 9:55:00 PM. 50 Premium Economy ticket for $13 per person are available. Travel duration is 4h 10m
Coronel Oviedo
La Santaniana
2h 5m
0
5:15 PM
Capiatá
Bus Stop
7:20 PM
Coronel Oviedo
Terminal de Ómnibus
0
Premium Economy
$6
A Bus from La Santaniana goes from Bus Stop, Capiatá (Paraguay) at 12/24/2025 5:15:00 PM to Terminal de Ómnibus, Coronel Oviedo (Paraguay) arriving at 12/24/2025 7:20:00 PM. 50 Premium Economy ticket for $6 per person are available. Travel duration is 2h 5m
Asunción, PY
La Santaniana
21h 0m
0
6:00 PM
Buenos Aires
Retiro Bus Station
3:00 PM
Asunción, PY
Bus Station Assunção
0
Premium Economy
$104
A Bus from La Santaniana goes from Retiro Bus Station, Buenos Aires (Argentina) at 1/6/2026 6:00:00 PM to Bus Station Assunção, Asunción, PY (Paraguay) arriving at 1/7/2026 3:00:00 PM. 50 Premium Economy ticket for $104 per person are available. Travel duration is 21h 0m
Buenos Aires
La Santaniana
23h 50m
0
7:50 AM
Ciudad del Este, PY
Central Bus Station
7:40 AM
Buenos Aires
Retiro Bus Station
0
First Class
$125
A Bus from La Santaniana goes from Central Bus Station, Ciudad del Este, PY (Paraguay) at 1/14/2026 7:50:00 AM to Retiro Bus Station, Buenos Aires (Argentina) arriving at 1/15/2026 7:40:00 AM. 50 First Class ticket for $125 per person are available. Travel duration is 23h 50m
Carapeguá
La Santaniana
22h 29m
0
2:51 PM
Villa Fiorito
Puente La Noria
1:20 PM
Carapeguá
Bus Stop
0
Premium Economy
$83
A Bus from La Santaniana goes from Puente La Noria, Villa Fiorito (Argentina) at 2/27/2026 2:51:00 PM to Bus Stop, Carapeguá (Paraguay) arriving at 2/28/2026 1:20:00 PM. 50 Premium Economy ticket for $83 per person are available. Travel duration is 22h 29m
Encarnacion
La Santaniana
14h 45m
0
6:06 PM
Buenos Aires
Retiro Bus Station
8:51 AM
Encarnacion
Bus Station
0
Economy
$125
A Bus from La Santaniana goes from Retiro Bus Station, Buenos Aires (Argentina) at 12/18/2025 6:06:00 PM to Bus Station, Encarnacion (Paraguay) arriving at 12/19/2025 8:51:00 AM. 50 Economy ticket for $125 per person are available. Travel duration is 14h 45m
Pedro Juan Caballero
La Santaniana
6h 0m
0
11:30 PM
Asunción, PY
Bus Station Assunção
5:30 AM
Pedro Juan Caballero
Central Bus Station
0
Premium Economy
$21
A Bus from La Santaniana goes from Bus Station Assunção, Asunción, PY (Paraguay) at 1/13/2026 11:30:00 PM to Central Bus Station, Pedro Juan Caballero (Paraguay) arriving at 1/14/2026 5:30:00 AM. 50 Premium Economy ticket for $21 per person are available. Travel duration is 6h 0m
Most popular cities served by La Santaniana
Below you can find the top destinations from La Santaniana:
On CheckMyBus, you will find all the 272 currently available bus connections from La Santaniana, to 68 cities worldwide, and you can compare them with the ones from all the other companies present on our website. Simply enter your departure and destination cities in our search, choose your desired travel date, specify how many people you are and off you go!
You can also sort your search results by price, departure and arrival time as well as duration. Use the filters to further narrow down the results by the number of transfers, specific stops, payment options, equipment and on-board services and much more, making it quick and easy to find your La Santaniana ticket.
On-board services of La Santaniana buses
Here you can see all the services that you will find aboard La Santaniana buses:
Free
Wi-Fi
Restrooms
Air-conditioning
Hand luggage
Free Luggage
Extra charges
Drinks
La Santaniana offers the following seat classes:
Economy
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
Premium Economy
A mix between Economy and Business, it offers extra legroom, WI-FI and possible snacks.
First Class
Best of the best: you will find the most comfortable accommodation to work or relax during your travel.
FAQs about La Santaniana
How do I find the cheapest ticket for La Santaniana?
You can use our search engine to find the cheapest trip from La Santaniana quickly and easily. Use the filter in our search engine and find all trips from La Santaniana directly.
How many days in advance should I book a ticket for La Santaniana?
In general, if you wait too long, you may pay more for your bus ticket. We at CheckMyBus have set the default time for booking a bus ticket for La Santaniana to around 3 days before departure. Early bookers therefore usually save more.
How can I book my ticket for La Santaniana?
Via CheckMyBus, you can see all the trips from La Santaniana. When you find the right trip within our search result list, click the yellow button for the respective trip. You will be redirected to the La Santaniana website. There you will be able to complete your booking.
What amenities are available on La Santaniana buses?
Aboard La Santaniana buses you will find many services: reclinable seats, AC and sockets to charge your electronic devices are the most common. You can find an overview of all the amenities and services offered at the section Bus amenities of La Santaniana.
How can I pay my ticket for La Santaniana?
To see which payment methods La Santaniana offers, have a look at Payment Methods for La Santaniana. Please note that CheckMyBus only serves as an intermediary, the payment of the ticket is made directly to La Santaniana.
How can I rate my trip with La Santaniana?
You can rate your trip with La Santaniana directly via CheckMyBus and share your experience with other travelers. Rate La Santaniana on a scale from 1 * to 5 ***** and tell others your opinion on a trip with La Santaniana.
How far in advance can you find bus trips with La Santaniana?
It is generally possible to check or book bus trips roughly six months in advance. If a provider only offers the route seasonally, you are welcome to contact CheckMyBus. We will then check when the next available bus of La Santaniana leaves for you.
How can I cancel my bus ticket from La Santaniana?
The cancellation policy of La Santaniana can vary by ticket class, individual trips or possible promotions. To check if you can cancel your ticket, we suggest checking the policies mentioned during the booking process of La Santaniana. For more information about cancellation and rescheduling, search for the Terms and Conditions on the company’s website.