Bus from Des Moines, IA to Boston, MA from $226

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Compare all timetables for the bus from Des Moines, IA to Boston, MA

Here is a selection of the cheapest bus trips from the schedule from Des Moines, IA to Boston, MA from various bus operators like Greyhound US for the next days.
today
from $226
tomorrow
Friday
Saturday
from $230
Sunday
Monday
from $231
Tuesday
from $226

Cheapest bus trips today

Prices are for one way and one person
  • Greyhound US
    48h 10m
    0
    5:30 AM
    Des Moines, IA
    Jefferson/Trailways Depot
    5:40 AM
    Boston, MA
    Allston
    0
    Greyhound US
    Economy
    $226
  • Greyhound US
    40h 5m
    0
    5:30 AM
    Des Moines, IA
    Jefferson/Trailways Depot
    9:35 PM
    Boston, MA
    South Station
    0
    Greyhound US
    Economy
    $228
  • Did you know that if you travel from Des Moines, IA to Boston, MA via Chicago, you can save more than $50? You can find the corresponding connections below.
    • FlixBus
      40h 5m
      0
      5:30 AM
      Des Moines, IA
      Jefferson/Trailways Depot
      1:35 PM
      Chicago
      Downtown Bus Station
      0
      FlixBus
      Economy
      $47
      • Waiting Time 5h 40m
    • Busbud
      26h 20m
      0
      7:15 PM
      Chicago
      Downtown Bus Station
      9:35 PM
      Boston, MA
      Atlantic and Beach St
      0
      Busbud
      Economy
      $129
    Travel time is the same as the direct connection, but you will save $50

Cheapest bus trips Saturday

Prices are for one way and one person
  • Greyhound US
    48h 10m
    0
    5:30 AM
    Des Moines, IA
    Jefferson/Trailways Depot
    5:40 AM
    Boston, MA
    Allston
    0
    Greyhound US
    Economy
    $230
  • Greyhound US
    40h 5m
    0
    5:30 AM
    Des Moines, IA
    Jefferson/Trailways Depot
    9:35 PM
    Boston, MA
    South Station
    0
    Greyhound US
    Economy
    $273
  • Did you know that if you travel from Des Moines, IA to Boston, MA via Chicago, you can save more than $106? You can find the corresponding connections below.
    • FlixBus
      48h 10m
      0
      5:30 AM
      Des Moines, IA
      Jefferson/Trailways Depot
      1:35 PM
      Chicago
      Downtown Bus Station
      0
      FlixBus
      Economy
      $47
      • Waiting Time 8h 30m
    • Busbud
      31h 35m
      0
      10:05 PM
      Chicago
      95th Red Line Station
      5:40 AM
      Boston, MA
      South Station
      0
      Busbud
      Economy
      $77
    Travel time is 8h 5m longer, but you will save $106

Cheapest bus trips Monday

Prices are for one way and one person
  • Greyhound US
    48h 10m
    0
    5:30 AM
    Des Moines, IA
    Jefferson/Trailways Depot
    5:40 AM
    Boston, MA
    Allston
    0
    Greyhound US
    Economy
    $231
  • Greyhound US
    40h 5m
    0
    5:30 AM
    Des Moines, IA
    Jefferson/Trailways Depot
    9:35 PM
    Boston, MA
    South Station
    0
    Greyhound US
    Economy
    $233
  • Did you know that if you travel from Des Moines, IA to Boston, MA via Chicago, you can save more than $107? You can find the corresponding connections below.
    • FlixBus
      48h 10m
      0
      5:30 AM
      Des Moines, IA
      Jefferson/Trailways Depot
      1:35 PM
      Chicago
      Downtown Bus Station
      0
      FlixBus
      Economy
      $47
      • Waiting Time 8h 30m
    • Busbud
      31h 35m
      0
      10:05 PM
      Chicago
      95th Red Line Station
      5:40 AM
      Boston, MA
      South Station
      0
      Busbud
      Economy
      $77
    Travel time is 8h 5m longer, but you will save $107

Cheapest bus trips Tuesday

Prices are for one way and one person
  • Greyhound US
    48h 10m
    0
    5:30 AM
    Des Moines, IA
    Jefferson/Trailways Depot
    5:40 AM
    Boston, MA
    Allston
    0
    Greyhound US
    Economy
    $226
  • Greyhound US
    40h 5m
    0
    5:30 AM
    Des Moines, IA
    Jefferson/Trailways Depot
    9:35 PM
    Boston, MA
    South Station
    0
    Greyhound US
    Economy
    $237
  • Did you know that if you travel from Des Moines, IA to Boston, MA via Chicago, you can save more than $102? You can find the corresponding connections below.
    • FlixBus
      48h 10m
      0
      5:30 AM
      Des Moines, IA
      Jefferson/Trailways Depot
      1:35 PM
      Chicago
      Downtown Bus Station
      0
      FlixBus
      Economy
      $47
      • Waiting Time 8h 30m
    • Busbud
      31h 35m
      0
      10:05 PM
      Chicago
      95th Red Line Station
      5:40 AM
      Boston, MA
      South Station
      0
      Busbud
      Economy
      $77
    Travel time is 8h 5m longer, but you will save $102

Facts about the bus from Des Moines, IA to Boston, MA

Compare all providers like Greyhound US that travel 2 times every day by bus from Des Moines, IA to Boston, MA in one click! Book your bus ticket from Des Moines, IA to Boston, MA starting from $226!

Cheapest Bus $226
Fastest Bus 40h 5m
Earliest Bus 5:30 AM
Latest Bus 5:30 AM
Daily Bus Routes 2 Ø
Distance 1,157.6 miles
Bus Companies Greyhound US

Cheapest bus connections from Des Moines, IA to Boston, MA

Every day, 2 buses from 1 bus companies leave Des Moines, IA for Boston, MA: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 06/18/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 06/15
Monday 06/16
Tuesday 06/17
Wednesday 06/18
$226
Thursday 06/19
Friday 06/20
Saturday 06/21
$230
Sunday 06/22
Monday 06/23
$231
Tuesday 06/24
$226
Wednesday 06/25
Thursday 06/26
Friday 06/27
Saturday 06/28
Sunday 06/29
Monday 06/30
Tuesday 07/01
Wednesday 07/02
Thursday 07/03
Friday 07/04
Saturday 07/05
Sunday 07/06
Monday 07/07
Tuesday 07/08
Wednesday 07/09
Thursday 07/10
Friday 07/11
Saturday 07/12

How to save money travelling from Des Moines, IA to Boston, MA

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Des Moines, IA to Boston, MA in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Des Moines, IA to Boston, MA, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Des Moines, IA to Boston, MA are also emptier.

All bus stations and stops in Des Moines, IA and Boston, MA

In the map below, you can see where to find all bus stations in Des Moines, IA and Boston, MA.

Service and Comfort on the bus from Des Moines, IA to Boston, MA

Want to know which seat classes are available on the buses from Des Moines, IA to Boston, MA? Or which bus companies serve the route Des Moines, IA to Boston, MA? Below you will find answers to your questions.

FAQs about the Des Moines, IA to Boston, MA bus

How much does a Des Moines, IA Boston, MA bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $226 and takes 48h 10m to reach Boston, MA. Compare offers to save money!

How much could I save by comparing buses from Des Moines, IA to Boston, MA?

This route is offered by 1 companies with a range of ticket prices between $226 and $273. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Boston, MA.

On average, how many connections are available from Des Moines, IA to Boston, MA each day?

Every day, the Des Moines, IA to Boston, MA bus route is served by approximately 2 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Des Moines, IA to Boston, MA take?

The fastest bus from Des Moines, IA to Boston, MA is offered by Greyhound US and takes 40h 5m. Bus tickets for this connection cost $228. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Des Moines, IA to Boston, MA?

The earliest bus arriving in Boston, MA from Des Moines, IA starts at 5:30 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Des Moines, IA to Boston, MA?

The latest bus trip departing from Des Moines, IA for Boston, MA starts at 5:30 AM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Des Moines, IA Boston, MA route?

When traveling by bus from Des Moines, IA to Boston, MA, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Des Moines, IA and Boston, MA?

You can check all the direct connections between Des Moines, IA and Boston, MA by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Des Moines, IA to Boston, MA bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Des Moines, IA Boston, MA bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Des Moines, IA Boston, MA bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Des Moines, IA to Boston, MA on your planned travel date.

Available seat classes which are offered on the bus route Des Moines, IA to Boston, MA

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Des Moines, IA and to Boston, MA

Here’s an overview of the most popular bus routes to Des Moines, IA and to Boston, MA. Simply click on the connection of your choice, and you will find all the details about your bus route!
Bus to Des Moines, IA from Chicago Bus to Des Moines, IA from Chicago
Buses Minneapolis to Des Moines, IA Buses Minneapolis to Des Moines, IA
Houston to Des Moines, IA bus Houston to Des Moines, IA bus
From Raleigh, NC to Des Moines, IA bus From Raleigh, NC to Des Moines, IA bus
Bus Portsmouth, NH - Boston, MA Bus Portsmouth, NH - Boston, MA
Bus from Northampton, MA to Boston, MA Bus from Northampton, MA to Boston, MA
Bus to Boston, MA from Bangor, ME Bus to Boston, MA from Bangor, ME
Buses from New York to Boston, MA Buses from New York to Boston, MA
Popular Airport Shuttles to Des Moines, IA and to Boston, MA
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