What is the best way to travel from Avignon to Frankfurt am Main?
Looking for a trip? Compare all the available Trains and Buses for the journey to Frankfurt am Main from Avignon. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 5 available companies to find your perfect trip!
What is the cheapest way to reach Frankfurt am Main from Avignon?
You can get to Frankfurt am Main with just $61 by taking a Bus from FlixBus, but you can find many more cheap offers: we have selected the best ones for next few days here for you.
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Sindbad13h 30m06:30 AMAvignonCentral Bus Station8:00 PMFrankfurt am MainCentral Bus Station0EconomyA Bus from Sindbad goes from Central Bus Station, Avignon (France) at 6/27/2026 6:30:00 AM to Central Bus Station, Frankfurt am Main (Germany) arriving at 6/27/2026 8:00:00 PM. 50 Economy ticket for $84 per person are available. Travel duration is 13h 30m
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TGV Lyria7h 15m08:45 AMAvignonTGV Train Station4:00 PMFrankfurt am MainCentral Station0EconomyA Train from TGV Lyria goes from TGV Train Station, Avignon (France) at 6/27/2026 8:45:00 AM to Central Station, Frankfurt am Main (Germany) arriving at 6/27/2026 4:00:00 PM. 50 Economy ticket for $130 per person are available. Travel duration is 7h 15m
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TGV Lyria8h 52m010:21 AMAvignonTGV Train Station7:13 PMFrankfurt am MainCentral Station0EconomyA Train from TGV Lyria goes from TGV Train Station, Avignon (France) at 6/27/2026 10:21:00 AM to Central Station, Frankfurt am Main (Germany) arriving at 6/27/2026 7:13:00 PM. 50 Economy ticket for $149 per person are available. Travel duration is 8h 52m
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TGV Lyria9h 10m02:04 PMAvignonCentral Station11:14 PMFrankfurt am MainCentral Station0EconomyA Train from TGV Lyria goes from Central Station, Avignon (France) at 6/27/2026 2:04:00 PM to Central Station, Frankfurt am Main (Germany) arriving at 6/27/2026 11:14:00 PM. 50 Economy ticket for $158 per person are available. Travel duration is 9h 10m
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TGV Lyria9h 14m02:04 PMAvignonCentral Station11:18 PMFrankfurt am MainCentral Station0EconomyA Train from TGV Lyria goes from Central Station, Avignon (France) at 6/27/2026 2:04:00 PM to Central Station, Frankfurt am Main (Germany) arriving at 6/27/2026 11:18:00 PM. 50 Economy ticket for $170 per person are available. Travel duration is 9h 14m
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TGV Lyria7h 46m07:10 AMAvignonTGV Train Station2:56 PMFrankfurt am MainCentral Station0EconomyA Train from TGV Lyria goes from TGV Train Station, Avignon (France) at 6/27/2026 7:10:00 AM to Central Station, Frankfurt am Main (Germany) arriving at 6/27/2026 2:56:00 PM. 50 Economy ticket for $176 per person are available. Travel duration is 7h 46m
Cheapest Buses Saturday
Cheapest Trains Saturday
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FlixBus19h 10m03:35 PMAvignonLe Pontet Bus Station10:45 AMFrankfurt am MainCentral Station0EconomyA Bus from FlixBus goes from Le Pontet Bus Station, Avignon (France) at 6/28/2026 3:35:00 PM to Central Station, Frankfurt am Main (Germany) arriving at 6/29/2026 10:45:00 AM. 50 Economy ticket for $67 per person are available. Travel duration is 19h 10m
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FlixBus16h 50m03:25 AMAvignonLe Pontet Bus Station8:15 PMFrankfurt am MainCentral Station0EconomyA Bus from FlixBus goes from Le Pontet Bus Station, Avignon (France) at 6/28/2026 3:25:00 AM to Central Station, Frankfurt am Main (Germany) arriving at 6/28/2026 8:15:00 PM. 50 Economy ticket for $69 per person are available. Travel duration is 16h 50m
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STARSHIPPER SAS16h 55m07:55 PMAvignonLe Pontet Bus Station12:50 PMFrankfurt am MainCentral Station0EconomyA Bus from STARSHIPPER SAS goes from Le Pontet Bus Station, Avignon (France) at 6/28/2026 7:55:00 PM to Central Station, Frankfurt am Main (Germany) arriving at 6/29/2026 12:50:00 PM. 50 Economy ticket for $70 per person are available. Travel duration is 16h 55m
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FlixBus18h 45m011:45 PMAvignonLe Pontet Bus Station6:30 PMFrankfurt am MainCentral Station0EconomyA Bus from FlixBus goes from Le Pontet Bus Station, Avignon (France) at 6/28/2026 11:45:00 PM to Central Station, Frankfurt am Main (Germany) arriving at 6/29/2026 6:30:00 PM. 50 Economy ticket for $89 per person are available. Travel duration is 18h 45m
Cheapest Buses Sunday
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FlixBus21h 5m08:45 AMAvignonLe Pontet Bus Station5:50 AMFrankfurt am MainCentral Station0EconomyA Bus from FlixBus goes from Le Pontet Bus Station, Avignon (France) at 7/1/2026 8:45:00 AM to Central Station, Frankfurt am Main (Germany) arriving at 7/2/2026 5:50:00 AM. 50 Economy ticket for $61 per person are available. Travel duration is 21h 5m
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FlixBus19h 10m03:35 PMAvignonLe Pontet Bus Station10:45 AMFrankfurt am MainCentral Station0EconomyA Bus from FlixBus goes from Le Pontet Bus Station, Avignon (France) at 7/1/2026 3:35:00 PM to Central Station, Frankfurt am Main (Germany) arriving at 7/2/2026 10:45:00 AM. 50 Economy ticket for $67 per person are available. Travel duration is 19h 10m
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FlixBus17h 50m07:00 PMAvignonLe Pontet Bus Station12:50 PMFrankfurt am MainCentral Station0EconomyA Bus from FlixBus goes from Le Pontet Bus Station, Avignon (France) at 7/1/2026 7:00:00 PM to Central Station, Frankfurt am Main (Germany) arriving at 7/2/2026 12:50:00 PM. 50 Economy ticket for $67 per person are available. Travel duration is 17h 50m
Cheapest Buses Wednesday
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FlixBus16h 25m012:15 AMAvignonLe Pontet Bus Station4:40 PMFrankfurt am MainCentral Station0EconomyA Bus from FlixBus goes from Le Pontet Bus Station, Avignon (France) at 7/3/2026 12:15:00 AM to Central Station, Frankfurt am Main (Germany) arriving at 7/3/2026 4:40:00 PM. 50 Economy ticket for $73 per person are available. Travel duration is 16h 25m
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FlixBus18h 30m04:15 PMAvignonLe Pontet Bus Station10:45 AMFrankfurt am MainCentral Station0EconomyA Bus from FlixBus goes from Le Pontet Bus Station, Avignon (France) at 7/3/2026 4:15:00 PM to Central Station, Frankfurt am Main (Germany) arriving at 7/4/2026 10:45:00 AM. 50 Economy ticket for $73 per person are available. Travel duration is 18h 30m
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FlixBus16h 5m08:40 PMAvignonLe Pontet Bus Station12:45 PMFrankfurt am MainCentral Station0EconomyA Bus from FlixBus goes from Le Pontet Bus Station, Avignon (France) at 7/3/2026 8:40:00 PM to Central Station, Frankfurt am Main (Germany) arriving at 7/4/2026 12:45:00 PM. 50 Economy ticket for $76 per person are available. Travel duration is 16h 5m
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FlixBus18h 45m011:45 PMAvignonLe Pontet Bus Station6:30 PMFrankfurt am MainCentral Station0EconomyA Bus from FlixBus goes from Le Pontet Bus Station, Avignon (France) at 7/3/2026 11:45:00 PM to Central Station, Frankfurt am Main (Germany) arriving at 7/4/2026 6:30:00 PM. 50 Economy ticket for $78 per person are available. Travel duration is 18h 45m
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FlixBus19h 35m010:15 AMAvignonLe Pontet Bus Station5:50 AMFrankfurt am MainCentral Station0EconomyA Bus from FlixBus goes from Le Pontet Bus Station, Avignon (France) at 7/3/2026 10:15:00 AM to Central Station, Frankfurt am Main (Germany) arriving at 7/4/2026 5:50:00 AM. 50 Economy ticket for $83 per person are available. Travel duration is 19h 35m
Cheapest Buses Friday
What are the fastest trips from Avignon to Frankfurt am Main?
You can get to Frankfurt am Main from Avignon in just 7h 15m with a Train from TGV Lyria. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.
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TGV Lyria7h 15m08:45 AMAvignonTGV Train Station4:00 PMFrankfurt am MainCentral Station0EconomyA Train from TGV Lyria goes from TGV Train Station, Avignon (France) at 6/27/2026 8:45:00 AM to Central Station, Frankfurt am Main (Germany) arriving at 6/27/2026 4:00:00 PM. 50 Economy ticket for $130 per person are available. Travel duration is 7h 15m
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TGV Lyria7h 46m07:10 AMAvignonTGV Train Station2:56 PMFrankfurt am MainCentral Station0EconomyA Train from TGV Lyria goes from TGV Train Station, Avignon (France) at 6/27/2026 7:10:00 AM to Central Station, Frankfurt am Main (Germany) arriving at 6/27/2026 2:56:00 PM. 50 Economy ticket for $176 per person are available. Travel duration is 7h 46m
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TGV Lyria8h 52m010:21 AMAvignonTGV Train Station7:13 PMFrankfurt am MainCentral Station0EconomyA Train from TGV Lyria goes from TGV Train Station, Avignon (France) at 6/27/2026 10:21:00 AM to Central Station, Frankfurt am Main (Germany) arriving at 6/27/2026 7:13:00 PM. 50 Economy ticket for $149 per person are available. Travel duration is 8h 52m
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TGV Lyria9h 10m02:04 PMAvignonCentral Station11:14 PMFrankfurt am MainCentral Station0EconomyA Train from TGV Lyria goes from Central Station, Avignon (France) at 6/27/2026 2:04:00 PM to Central Station, Frankfurt am Main (Germany) arriving at 6/27/2026 11:14:00 PM. 50 Economy ticket for $158 per person are available. Travel duration is 9h 10m
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TGV Lyria9h 14m02:04 PMAvignonCentral Station11:18 PMFrankfurt am MainCentral Station0EconomyA Train from TGV Lyria goes from Central Station, Avignon (France) at 6/27/2026 2:04:00 PM to Central Station, Frankfurt am Main (Germany) arriving at 6/27/2026 11:18:00 PM. 50 Economy ticket for $170 per person are available. Travel duration is 9h 14m
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Sindbad13h 30m06:30 AMAvignonCentral Bus Station8:00 PMFrankfurt am MainCentral Bus Station0EconomyA Bus from Sindbad goes from Central Bus Station, Avignon (France) at 6/27/2026 6:30:00 AM to Central Bus Station, Frankfurt am Main (Germany) arriving at 6/27/2026 8:00:00 PM. 50 Economy ticket for $84 per person are available. Travel duration is 13h 30m
Fastest Trains Saturday
Fastest Buses Saturday
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FlixBus16h 50m03:25 AMAvignonLe Pontet Bus Station8:15 PMFrankfurt am MainCentral Station0EconomyA Bus from FlixBus goes from Le Pontet Bus Station, Avignon (France) at 6/28/2026 3:25:00 AM to Central Station, Frankfurt am Main (Germany) arriving at 6/28/2026 8:15:00 PM. 50 Economy ticket for $69 per person are available. Travel duration is 16h 50m
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STARSHIPPER SAS16h 55m07:55 PMAvignonLe Pontet Bus Station12:50 PMFrankfurt am MainCentral Station0EconomyA Bus from STARSHIPPER SAS goes from Le Pontet Bus Station, Avignon (France) at 6/28/2026 7:55:00 PM to Central Station, Frankfurt am Main (Germany) arriving at 6/29/2026 12:50:00 PM. 50 Economy ticket for $70 per person are available. Travel duration is 16h 55m
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FlixBus18h 45m011:45 PMAvignonLe Pontet Bus Station6:30 PMFrankfurt am MainCentral Station0EconomyA Bus from FlixBus goes from Le Pontet Bus Station, Avignon (France) at 6/28/2026 11:45:00 PM to Central Station, Frankfurt am Main (Germany) arriving at 6/29/2026 6:30:00 PM. 50 Economy ticket for $89 per person are available. Travel duration is 18h 45m
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FlixBus19h 10m03:35 PMAvignonLe Pontet Bus Station10:45 AMFrankfurt am MainCentral Station0EconomyA Bus from FlixBus goes from Le Pontet Bus Station, Avignon (France) at 6/28/2026 3:35:00 PM to Central Station, Frankfurt am Main (Germany) arriving at 6/29/2026 10:45:00 AM. 50 Economy ticket for $67 per person are available. Travel duration is 19h 10m
Fastest Buses Sunday
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FlixBus17h 50m07:00 PMAvignonLe Pontet Bus Station12:50 PMFrankfurt am MainCentral Station0EconomyA Bus from FlixBus goes from Le Pontet Bus Station, Avignon (France) at 7/1/2026 7:00:00 PM to Central Station, Frankfurt am Main (Germany) arriving at 7/2/2026 12:50:00 PM. 50 Economy ticket for $67 per person are available. Travel duration is 17h 50m
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FlixBus19h 10m03:35 PMAvignonLe Pontet Bus Station10:45 AMFrankfurt am MainCentral Station0EconomyA Bus from FlixBus goes from Le Pontet Bus Station, Avignon (France) at 7/1/2026 3:35:00 PM to Central Station, Frankfurt am Main (Germany) arriving at 7/2/2026 10:45:00 AM. 50 Economy ticket for $67 per person are available. Travel duration is 19h 10m
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FlixBus21h 5m08:45 AMAvignonLe Pontet Bus Station5:50 AMFrankfurt am MainCentral Station0EconomyA Bus from FlixBus goes from Le Pontet Bus Station, Avignon (France) at 7/1/2026 8:45:00 AM to Central Station, Frankfurt am Main (Germany) arriving at 7/2/2026 5:50:00 AM. 50 Economy ticket for $61 per person are available. Travel duration is 21h 5m
Fastest Buses Wednesday
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FlixBus16h 5m08:40 PMAvignonLe Pontet Bus Station12:45 PMFrankfurt am MainCentral Station0EconomyA Bus from FlixBus goes from Le Pontet Bus Station, Avignon (France) at 7/3/2026 8:40:00 PM to Central Station, Frankfurt am Main (Germany) arriving at 7/4/2026 12:45:00 PM. 50 Economy ticket for $76 per person are available. Travel duration is 16h 5m
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FlixBus16h 25m012:15 AMAvignonLe Pontet Bus Station4:40 PMFrankfurt am MainCentral Station0EconomyA Bus from FlixBus goes from Le Pontet Bus Station, Avignon (France) at 7/3/2026 12:15:00 AM to Central Station, Frankfurt am Main (Germany) arriving at 7/3/2026 4:40:00 PM. 50 Economy ticket for $73 per person are available. Travel duration is 16h 25m
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FlixBus18h 30m04:15 PMAvignonLe Pontet Bus Station10:45 AMFrankfurt am MainCentral Station0EconomyA Bus from FlixBus goes from Le Pontet Bus Station, Avignon (France) at 7/3/2026 4:15:00 PM to Central Station, Frankfurt am Main (Germany) arriving at 7/4/2026 10:45:00 AM. 50 Economy ticket for $73 per person are available. Travel duration is 18h 30m
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FlixBus18h 45m011:45 PMAvignonLe Pontet Bus Station6:30 PMFrankfurt am MainCentral Station0EconomyA Bus from FlixBus goes from Le Pontet Bus Station, Avignon (France) at 7/3/2026 11:45:00 PM to Central Station, Frankfurt am Main (Germany) arriving at 7/4/2026 6:30:00 PM. 50 Economy ticket for $78 per person are available. Travel duration is 18h 45m
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FlixBus19h 35m010:15 AMAvignonLe Pontet Bus Station5:50 AMFrankfurt am MainCentral Station0EconomyA Bus from FlixBus goes from Le Pontet Bus Station, Avignon (France) at 7/3/2026 10:15:00 AM to Central Station, Frankfurt am Main (Germany) arriving at 7/4/2026 5:50:00 AM. 50 Economy ticket for $83 per person are available. Travel duration is 19h 35m
Fastest Buses Friday
Here you will find all operators and timetables for a
Bus from Avignon to Frankfurt am Main
What are the most popular stations in Avignon and Frankfurt am Main?
In Avignon, you will usually depart from Central Bus Station, Montfavet Train Station or TGV Train Station, while in Frankfurt am Main you will be arriving at Central Station, Central Bus Station or West Train Station, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Frankfurt am Main from Avignon? With 4 connections between 5 Train and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Avignon and Frankfurt am Main, you can pay as low as $61 with a Bus from FlixBus.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Train from TGV Lyria: you will get to Frankfurt am Main in just 7h 15m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Avignon and Frankfurt am Main are FlixBus, TGV Lyria and Sindbad, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Avignon and Frankfurt am Main is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Rognonas or to Neu-Isenburg, and look at flights from Avignon Airport, and landing at Frankfurt am Main Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Avignon to Frankfurt am Main?
The most popular companies between Avignon and Frankfurt am Main, are FlixBus, TGV Lyria and Sindbad. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: FlixBus, Sindbad and STARSHIPPER SAS
Train companies: TGV Lyria
All you need to know when you travel from Avignon to Frankfurt am Main
Check all information on comfort and services on all modes of transports from Avignon to Frankfurt am Main. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Avignon to Frankfurt am Main
How can I reach Frankfurt am Main from Avignon?
Every day, there are on average 4 connections between Train and Bus, with which you can get to Frankfurt am Main from Avignon.
How far is Frankfurt am Main from Avignon?
The distance between Avignon and Frankfurt am Main is 463.2 miles.
What is the most ecofriendly mode of transport between Avignon and Frankfurt am Main?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 20 kgs of CO2, a train 26 kgs, a car 127 kgs, and a flight 183 kgs.
What is the cheapest mode of transport from Avignon to Frankfurt am Main?
You can get to Frankfurt am Main with just $61 by taking a Bus from FlixBus.
What is the fastest way to get from Avignon to Frankfurt am Main?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Frankfurt am Main in just 7h 15m with a Train from TGV Lyria.
More routes to Avignon and to Frankfurt am Main
Looking for more options? Here you can see the most popular routes to Avignon and to Frankfurt am Main. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Avignon
- Aix-en-Provence to Avignon
- Alicante to Avignon
- Barcelona to Avignon
- Geneva to Avignon
- Grenoble to Avignon
- Lille to Avignon
- London to Avignon
- Lyon to Avignon
- Marseille Airport to Avignon
- Marseille to Avignon
- Montpellier to Avignon
- Nice Airport to Avignon
- Paris Orly Airport to Avignon
- Paris to Avignon
- Perpignan to Avignon
- Rennes to Avignon
- Toulon to Avignon
- Toulouse to Avignon
- Tours to Avignon
- Trips to Frankfurt am Main
- Amsterdam to Frankfurt am Main
- Basel to Frankfurt am Main
- Belgrade to Frankfurt am Main
- Berlin to Frankfurt am Main
- Bielefeld to Frankfurt am Main
- Birmingham to Frankfurt am Main
- Cologne to Frankfurt am Main
- Duisburg to Frankfurt am Main
- Dusseldorf to Frankfurt am Main
- Frankfurt Hahn Airport to Frankfurt am Main
- Graz to Frankfurt am Main
- Hamburg to Frankfurt am Main
- Hanover to Frankfurt am Main
- Linz to Frankfurt am Main
- London to Frankfurt am Main
- Marburg (Lahn) to Frankfurt am Main
- Munich to Frankfurt am Main
- Paris to Frankfurt am Main
- Prague to Frankfurt am Main
- Priština to Frankfurt am Main
- Saarbruecken to Frankfurt am Main
- Stuttgart to Frankfurt am Main
- Vienna to Frankfurt am Main
- Zurich to Frankfurt am Main
