What is the best way to travel from Charleston, SC to Jacksonville, FL?
Looking for a trip? Compare all the available Buses and Flights for the journey to Jacksonville, FL from Charleston, SC. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 1 available companies to find your perfect trip!
What is the cheapest way to reach Jacksonville, FL from Charleston, SC?
You can get to Jacksonville, FL with just $55 by taking a Bus from Greyhound US, but you can find many more cheap offers: we have selected the best ones for next few days here for you.
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Greyhound US10h 10m011:15 AMCharleston, SCBus Station9:25 PMJacksonville, FLAmtrak Train Station0EconomyA Bus from Greyhound US goes from Bus Station, Charleston, SC (USA) at 12/5/2025 11:15:00 AM to Amtrak Train Station, Jacksonville, FL (USA) arriving at 12/5/2025 9:25:00 PM. 50 Economy ticket for $55 per person are available. Travel duration is 10h 10m
Cheapest Buses Friday
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Greyhound US10h 10m011:15 AMCharleston, SCBus Station9:25 PMJacksonville, FLAmtrak Train Station0EconomyA Bus from Greyhound US goes from Bus Station, Charleston, SC (USA) at 12/6/2025 11:15:00 AM to Amtrak Train Station, Jacksonville, FL (USA) arriving at 12/6/2025 9:25:00 PM. 50 Economy ticket for $57 per person are available. Travel duration is 10h 10m
Cheapest Buses Saturday
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Greyhound US10h 10m011:15 AMCharleston, SCBus Station9:25 PMJacksonville, FLAmtrak Train Station0EconomyA Bus from Greyhound US goes from Bus Station, Charleston, SC (USA) at 12/8/2025 11:15:00 AM to Amtrak Train Station, Jacksonville, FL (USA) arriving at 12/8/2025 9:25:00 PM. 50 Economy ticket for $60 per person are available. Travel duration is 10h 10m
Cheapest Buses Monday
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Greyhound US10h 10m011:15 AMCharleston, SCBus Station9:25 PMJacksonville, FLAmtrak Train Station0EconomyA Bus from Greyhound US goes from Bus Station, Charleston, SC (USA) at 12/11/2025 11:15:00 AM to Amtrak Train Station, Jacksonville, FL (USA) arriving at 12/11/2025 9:25:00 PM. 50 Economy ticket for $84 per person are available. Travel duration is 10h 10m
Cheapest Buses Thursday
What are the fastest trips from Charleston, SC to Jacksonville, FL?
You can get to Jacksonville, FL from Charleston, SC in just 10h 10m with a Bus from Greyhound US. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.
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Greyhound US10h 10m011:15 AMCharleston, SCBus Station9:25 PMJacksonville, FLAmtrak Train Station0EconomyA Bus from Greyhound US goes from Bus Station, Charleston, SC (USA) at 12/5/2025 11:15:00 AM to Amtrak Train Station, Jacksonville, FL (USA) arriving at 12/5/2025 9:25:00 PM. 50 Economy ticket for $55 per person are available. Travel duration is 10h 10m
Fastest Buses Friday
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Greyhound US10h 10m011:15 AMCharleston, SCBus Station9:25 PMJacksonville, FLAmtrak Train Station0EconomyA Bus from Greyhound US goes from Bus Station, Charleston, SC (USA) at 12/6/2025 11:15:00 AM to Amtrak Train Station, Jacksonville, FL (USA) arriving at 12/6/2025 9:25:00 PM. 50 Economy ticket for $57 per person are available. Travel duration is 10h 10m
Fastest Buses Saturday
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Greyhound US10h 10m011:15 AMCharleston, SCBus Station9:25 PMJacksonville, FLAmtrak Train Station0EconomyA Bus from Greyhound US goes from Bus Station, Charleston, SC (USA) at 12/8/2025 11:15:00 AM to Amtrak Train Station, Jacksonville, FL (USA) arriving at 12/8/2025 9:25:00 PM. 50 Economy ticket for $60 per person are available. Travel duration is 10h 10m
Fastest Buses Monday
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Greyhound US10h 10m011:15 AMCharleston, SCBus Station9:25 PMJacksonville, FLAmtrak Train Station0EconomyA Bus from Greyhound US goes from Bus Station, Charleston, SC (USA) at 12/11/2025 11:15:00 AM to Amtrak Train Station, Jacksonville, FL (USA) arriving at 12/11/2025 9:25:00 PM. 50 Economy ticket for $84 per person are available. Travel duration is 10h 10m
Fastest Buses Thursday
Here you will find all operators and timetables for a
Bus from Charleston, SC to Jacksonville, FL
What are the most popular stations in Charleston, SC and Jacksonville, FL?
In Charleston, SC, you will usually depart from Bus Station or BI-LO Shopping Center Downtown, while in Jacksonville, FL you will be arriving at Downtown Bus Stop, Amtrak Train Station or Central Bus Station, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Jacksonville, FL from Charleston, SC? With 1 connections between 1 Bus and Flight operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Charleston, SC and Jacksonville, FL, you can pay as low as $55 with a Bus from Greyhound US.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Bus from Greyhound US: you will get to Jacksonville, FL in just 10h 10m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Charleston, SC and Jacksonville, FL are Greyhound US, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Charleston, SC and Jacksonville, FL is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Mount Pleasant, SC or to Jacksonville, and look at flights from Charleston Airport, and landing at Jacksonville Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Charleston, SC to Jacksonville, FL?
The most popular companies between Charleston, SC and Jacksonville, FL, are Greyhound US. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: Greyhound US
All you need to know when you travel from Charleston, SC to Jacksonville, FL
Check all information on comfort and services on all modes of transports from Charleston, SC to Jacksonville, FL. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Charleston, SC to Jacksonville, FL
How can I reach Jacksonville, FL from Charleston, SC?
Every day, there are on average 1 connections between Bus and Flight, with which you can get to Jacksonville, FL from Charleston, SC.
How far is Jacksonville, FL from Charleston, SC?
The distance between Charleston, SC and Jacksonville, FL is 197.8 miles.
What is the most ecofriendly mode of transport between Charleston, SC and Jacksonville, FL?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 9 kgs of CO2, a train 11 kgs, a car 54 kgs, and a flight 78 kgs.
What is the cheapest mode of transport from Charleston, SC to Jacksonville, FL?
You can get to Jacksonville, FL with just $55 by taking a Bus from Greyhound US.
What is the fastest way to get from Charleston, SC to Jacksonville, FL?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Jacksonville, FL in just 10h 10m with a Bus from Greyhound US.
More routes to Charleston, SC and to Jacksonville, FL
Looking for more options? Here you can see the most popular routes to Charleston, SC and to Jacksonville, FL. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Charleston, SC
- Atlanta, GA to Charleston, SC
- New York to Charleston, SC
- Washington, DC to Charleston, SC

