What is the best way to travel from Chicago to Buffalo, NY?
Looking for a trip? Compare all the available Flights and Buses for the journey to Buffalo, NY from Chicago. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 2 available companies to find your perfect trip!
What is the cheapest way to reach Buffalo, NY from Chicago?
You can get to Buffalo, NY with just $50 by taking a Bus from Greyhound US, but you can find many more cheap offers: we have selected the best ones for next few days here for you.
-
Greyhound US13h 0m06:00 PMChicagoDowntown Bus Station8:00 AMBuffalo, NYCentral Bus Station0EconomyA Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 6/2/2026 6:00:00 PM to Central Bus Station, Buffalo, NY (USA) arriving at 6/3/2026 8:00:00 AM. 50 Economy ticket for $50 per person are available. Travel duration is 13h 0m
-
FlixBus20h 30m07:15 PMChicagoDowntown Bus Station4:45 PMBuffalo, NYCentral Bus Station0EconomyA Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 6/2/2026 7:15:00 PM to Central Bus Station, Buffalo, NY (USA) arriving at 6/3/2026 4:45:00 PM. 50 Economy ticket for $52 per person are available. Travel duration is 20h 30m
-
Greyhound US20h 45m010:15 AMChicagoCanal & Van Buren8:00 AMBuffalo, NYCentral Bus Station0EconomyA Bus from Greyhound US goes from Canal & Van Buren, Chicago (USA) at 6/2/2026 10:15:00 AM to Central Bus Station, Buffalo, NY (USA) arriving at 6/3/2026 8:00:00 AM. 50 Economy ticket for $54 per person are available. Travel duration is 20h 45m
-
Frontier Airlines24h 27m012:27 PMChicago Midway AirportChicago Midway Airport1:54 PMBuffalo AirportBuffalo Airport0EconomyA Flight from Frontier Airlines goes from Chicago Midway Airport, Chicago Midway Airport (USA) at 6/2/2026 12:27:00 PM to Buffalo Airport, Buffalo Airport (USA) arriving at 6/3/2026 1:54:00 PM. 50 Economy ticket for $67 per person are available. Travel duration is 24h 27m
-
United Airlines1h 46m01:55 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center4:41 PMBuffalo AirportBuffalo Airport0EconomyA Flight from United Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/2/2026 1:55:00 PM to Buffalo Airport, Buffalo Airport (USA) arriving at 6/2/2026 4:41:00 PM. 50 Economy ticket for $118 per person are available. Travel duration is 1h 46m
-
United Airlines1h 46m06:17 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center9:03 PMBuffalo AirportBuffalo Airport0EconomyA Flight from United Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/2/2026 6:17:00 PM to Buffalo Airport, Buffalo Airport (USA) arriving at 6/2/2026 9:03:00 PM. 50 Economy ticket for $118 per person are available. Travel duration is 1h 46m
-
Skyscanner1h 48m07:27 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center10:15 AMBuffalo AirportBuffalo Airport0EconomyA Flight from Skyscanner goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/2/2026 7:27:00 AM to Buffalo Airport, Buffalo Airport (USA) arriving at 6/2/2026 10:15:00 AM. 50 Economy ticket for $161 per person are available. Travel duration is 1h 48m
Cheapest Buses Tuesday
Cheapest Flights Tuesday
-
Greyhound US13h 0m06:00 PMChicagoDowntown Bus Station8:00 AMBuffalo, NYCentral Bus Station0EconomyA Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 6/3/2026 6:00:00 PM to Central Bus Station, Buffalo, NY (USA) arriving at 6/4/2026 8:00:00 AM. 50 Economy ticket for $52 per person are available. Travel duration is 13h 0m
-
FlixBus20h 30m07:15 PMChicagoDowntown Bus Station4:45 PMBuffalo, NYCentral Bus Station0EconomyA Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 6/3/2026 7:15:00 PM to Central Bus Station, Buffalo, NY (USA) arriving at 6/4/2026 4:45:00 PM. 50 Economy ticket for $52 per person are available. Travel duration is 20h 30m
-
Greyhound US20h 45m010:15 AMChicagoCanal & Van Buren8:00 AMBuffalo, NYCentral Bus Station0EconomyA Bus from Greyhound US goes from Canal & Van Buren, Chicago (USA) at 6/3/2026 10:15:00 AM to Central Bus Station, Buffalo, NY (USA) arriving at 6/4/2026 8:00:00 AM. 50 Economy ticket for $54 per person are available. Travel duration is 20h 45m
-
Frontier Airlines6h 54m06:00 AMChicago Midway AirportChicago Midway Airport1:54 PMBuffalo AirportBuffalo Airport0EconomyA Flight from Frontier Airlines goes from Chicago Midway Airport, Chicago Midway Airport (USA) at 6/3/2026 6:00:00 AM to Buffalo Airport, Buffalo Airport (USA) arriving at 6/3/2026 1:54:00 PM. 50 Economy ticket for $69 per person are available. Travel duration is 6h 54m
-
Frontier Airlines21h 37m012:04 PMChicago Midway AirportChicago Midway Airport10:41 AMBuffalo AirportBuffalo Airport0EconomyA Flight from Frontier Airlines goes from Chicago Midway Airport, Chicago Midway Airport (USA) at 6/3/2026 12:04:00 PM to Buffalo Airport, Buffalo Airport (USA) arriving at 6/4/2026 10:41:00 AM. 50 Economy ticket for $69 per person are available. Travel duration is 21h 37m
-
Skyscanner1h 48m07:27 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center10:15 AMBuffalo AirportBuffalo Airport0EconomyA Flight from Skyscanner goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/3/2026 7:27:00 AM to Buffalo Airport, Buffalo Airport (USA) arriving at 6/3/2026 10:15:00 AM. 50 Economy ticket for $117 per person are available. Travel duration is 1h 48m
-
United Airlines1h 46m06:17 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center9:03 PMBuffalo AirportBuffalo Airport0EconomyA Flight from United Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/3/2026 6:17:00 PM to Buffalo Airport, Buffalo Airport (USA) arriving at 6/3/2026 9:03:00 PM. 50 Economy ticket for $117 per person are available. Travel duration is 1h 46m
-
United Airlines1h 48m07:27 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center10:15 AMBuffalo AirportBuffalo Airport0EconomyA Flight from United Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/3/2026 7:27:00 AM to Buffalo Airport, Buffalo Airport (USA) arriving at 6/3/2026 10:15:00 AM. 50 Economy ticket for $118 per person are available. Travel duration is 1h 48m
-
Frontier Airlines29h 7m012:04 PMChicago Midway AirportChicago Midway Airport6:11 PMNiagara Falls AirportNiagara Falls Airport0EconomyA Flight from Frontier Airlines goes from Chicago Midway Airport, Chicago Midway Airport (USA) at 6/3/2026 12:04:00 PM to Niagara Falls Airport, Niagara Falls Airport (USA) arriving at 6/4/2026 6:11:00 PM. 50 Economy ticket for $220 per person are available. Travel duration is 29h 7m
Cheapest Buses Wednesday
Cheapest Flights Wednesday
-
FlixBus20h 30m07:15 PMChicagoDowntown Bus Station4:45 PMBuffalo, NYCentral Bus Station0EconomyA Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 6/4/2026 7:15:00 PM to Central Bus Station, Buffalo, NY (USA) arriving at 6/5/2026 4:45:00 PM. 50 Economy ticket for $55 per person are available. Travel duration is 20h 30m
-
Greyhound US20h 45m010:15 AMChicagoCanal & Van Buren8:00 AMBuffalo, NYCentral Bus Station0EconomyA Bus from Greyhound US goes from Canal & Van Buren, Chicago (USA) at 6/4/2026 10:15:00 AM to Central Bus Station, Buffalo, NY (USA) arriving at 6/5/2026 8:00:00 AM. 50 Economy ticket for $56 per person are available. Travel duration is 20h 45m
-
Greyhound US13h 0m06:00 PMChicagoDowntown Bus Station8:00 AMBuffalo, NYCentral Bus Station0EconomyA Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 6/4/2026 6:00:00 PM to Central Bus Station, Buffalo, NY (USA) arriving at 6/5/2026 8:00:00 AM. 50 Economy ticket for $56 per person are available. Travel duration is 13h 0m
-
Frontier Airlines24h 27m012:27 PMChicago Midway AirportChicago Midway Airport1:54 PMBuffalo AirportBuffalo Airport0EconomyA Flight from Frontier Airlines goes from Chicago Midway Airport, Chicago Midway Airport (USA) at 6/4/2026 12:27:00 PM to Buffalo Airport, Buffalo Airport (USA) arriving at 6/5/2026 1:54:00 PM. 50 Economy ticket for $77 per person are available. Travel duration is 24h 27m
-
Frontier Airlines23h 25m01:29 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center1:54 PMBuffalo AirportBuffalo Airport0EconomyA Flight from Frontier Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/4/2026 1:29:00 PM to Buffalo Airport, Buffalo Airport (USA) arriving at 6/5/2026 1:54:00 PM. 50 Economy ticket for $77 per person are available. Travel duration is 23h 25m
-
Skyscanner1h 48m07:27 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center10:15 AMBuffalo AirportBuffalo Airport0EconomyA Flight from Skyscanner goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/4/2026 7:27:00 AM to Buffalo Airport, Buffalo Airport (USA) arriving at 6/4/2026 10:15:00 AM. 50 Economy ticket for $173 per person are available. Travel duration is 1h 48m
-
United Airlines1h 46m01:55 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center4:41 PMBuffalo AirportBuffalo Airport0EconomyA Flight from United Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/4/2026 1:55:00 PM to Buffalo Airport, Buffalo Airport (USA) arriving at 6/4/2026 4:41:00 PM. 50 Economy ticket for $173 per person are available. Travel duration is 1h 46m
-
United Airlines1h 46m06:17 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center9:03 PMBuffalo AirportBuffalo Airport0EconomyA Flight from United Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/4/2026 6:17:00 PM to Buffalo Airport, Buffalo Airport (USA) arriving at 6/4/2026 9:03:00 PM. 50 Economy ticket for $173 per person are available. Travel duration is 1h 46m
-
Allegiant Air30h 47m09:11 AMChicago Midway AirportChicago Midway Airport4:58 PMNiagara Falls AirportNiagara Falls Airport0EconomyA Flight from Allegiant Air goes from Chicago Midway Airport, Chicago Midway Airport (USA) at 6/4/2026 9:11:00 AM to Niagara Falls Airport, Niagara Falls Airport (USA) arriving at 6/5/2026 4:58:00 PM. 50 Economy ticket for $256 per person are available. Travel duration is 30h 47m
Cheapest Buses Thursday
Cheapest Flights Thursday
-
Greyhound US13h 0m06:00 PMChicagoDowntown Bus Station8:00 AMBuffalo, NYCentral Bus Station0EconomyA Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 6/5/2026 6:00:00 PM to Central Bus Station, Buffalo, NY (USA) arriving at 6/6/2026 8:00:00 AM. 50 Economy ticket for $60 per person are available. Travel duration is 13h 0m
-
FlixBus20h 30m07:15 PMChicagoDowntown Bus Station4:45 PMBuffalo, NYCentral Bus Station0EconomyA Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 6/5/2026 7:15:00 PM to Central Bus Station, Buffalo, NY (USA) arriving at 6/6/2026 4:45:00 PM. 50 Economy ticket for $60 per person are available. Travel duration is 20h 30m
-
Greyhound US20h 45m010:15 AMChicagoUnion Station8:00 AMBuffalo, NYCentral Bus Station0EconomyA Bus from Greyhound US goes from Union Station, Chicago (USA) at 6/5/2026 10:15:00 AM to Central Bus Station, Buffalo, NY (USA) arriving at 6/6/2026 8:00:00 AM. 50 Economy ticket for $80 per person are available. Travel duration is 20h 45m
-
Frontier Airlines5h 59m06:55 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center1:54 PMBuffalo AirportBuffalo Airport0EconomyA Flight from Frontier Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/5/2026 6:55:00 AM to Buffalo Airport, Buffalo Airport (USA) arriving at 6/5/2026 1:54:00 PM. 50 Economy ticket for $111 per person are available. Travel duration is 5h 59m
-
Frontier Airlines6h 54m06:00 AMChicago Midway AirportChicago Midway Airport1:54 PMBuffalo AirportBuffalo Airport0EconomyA Flight from Frontier Airlines goes from Chicago Midway Airport, Chicago Midway Airport (USA) at 6/5/2026 6:00:00 AM to Buffalo Airport, Buffalo Airport (USA) arriving at 6/5/2026 1:54:00 PM. 50 Economy ticket for $114 per person are available. Travel duration is 6h 54m
-
United Airlines1h 46m01:55 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center4:41 PMBuffalo AirportBuffalo Airport0EconomyA Flight from United Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/5/2026 1:55:00 PM to Buffalo Airport, Buffalo Airport (USA) arriving at 6/5/2026 4:41:00 PM. 50 Economy ticket for $173 per person are available. Travel duration is 1h 46m
-
United Airlines1h 46m06:17 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center9:03 PMBuffalo AirportBuffalo Airport0EconomyA Flight from United Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/5/2026 6:17:00 PM to Buffalo Airport, Buffalo Airport (USA) arriving at 6/5/2026 9:03:00 PM. 50 Economy ticket for $173 per person are available. Travel duration is 1h 46m
-
JetBlue Airways7h 32m03:27 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center11:59 PMBuffalo AirportBuffalo Airport0EconomyA Flight from JetBlue Airways goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/5/2026 3:27:00 PM to Buffalo Airport, Buffalo Airport (USA) arriving at 6/5/2026 11:59:00 PM. 50 Economy ticket for $175 per person are available. Travel duration is 7h 32m
Cheapest Buses Friday
Cheapest Flights Friday
-
Greyhound US20h 45m010:15 AMChicagoCanal & Van Buren8:00 AMBuffalo, NYCentral Bus Station0EconomyA Bus from Greyhound US goes from Canal & Van Buren, Chicago (USA) at 6/6/2026 10:15:00 AM to Central Bus Station, Buffalo, NY (USA) arriving at 6/7/2026 8:00:00 AM. 50 Economy ticket for $58 per person are available. Travel duration is 20h 45m
-
Greyhound US13h 0m06:00 PMChicagoDowntown Bus Station8:00 AMBuffalo, NYCentral Bus Station0EconomyA Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 6/6/2026 6:00:00 PM to Central Bus Station, Buffalo, NY (USA) arriving at 6/7/2026 8:00:00 AM. 50 Economy ticket for $58 per person are available. Travel duration is 13h 0m
-
FlixBus20h 30m07:15 PMChicagoDowntown Bus Station4:45 PMBuffalo, NYCentral Bus Station0EconomyA Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 6/6/2026 7:15:00 PM to Central Bus Station, Buffalo, NY (USA) arriving at 6/7/2026 4:45:00 PM. 50 Economy ticket for $58 per person are available. Travel duration is 20h 30m
-
Frontier Airlines21h 42m011:59 AMChicago Midway AirportChicago Midway Airport10:41 AMBuffalo AirportBuffalo Airport0EconomyA Flight from Frontier Airlines goes from Chicago Midway Airport, Chicago Midway Airport (USA) at 6/6/2026 11:59:00 AM to Buffalo Airport, Buffalo Airport (USA) arriving at 6/7/2026 10:41:00 AM. 50 Economy ticket for $119 per person are available. Travel duration is 21h 42m
-
United Airlines1h 46m01:55 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center4:41 PMBuffalo AirportBuffalo Airport0EconomyA Flight from United Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/6/2026 1:55:00 PM to Buffalo Airport, Buffalo Airport (USA) arriving at 6/6/2026 4:41:00 PM. 50 Economy ticket for $131 per person are available. Travel duration is 1h 46m
-
United Airlines1h 46m06:17 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center9:03 PMBuffalo AirportBuffalo Airport0EconomyA Flight from United Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/6/2026 6:17:00 PM to Buffalo Airport, Buffalo Airport (USA) arriving at 6/6/2026 9:03:00 PM. 50 Economy ticket for $131 per person are available. Travel duration is 1h 46m
-
Skyscanner1h 48m07:27 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center10:15 AMBuffalo AirportBuffalo Airport0EconomyA Flight from Skyscanner goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/6/2026 7:27:00 AM to Buffalo Airport, Buffalo Airport (USA) arriving at 6/6/2026 10:15:00 AM. 50 Economy ticket for $131 per person are available. Travel duration is 1h 48m
-
Frontier Airlines27h 42m01:29 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center6:11 PMNiagara Falls AirportNiagara Falls Airport0EconomyA Flight from Frontier Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/6/2026 1:29:00 PM to Niagara Falls Airport, Niagara Falls Airport (USA) arriving at 6/7/2026 6:11:00 PM. 50 Economy ticket for $209 per person are available. Travel duration is 27h 42m
-
Frontier Airlines29h 12m011:59 AMChicago Midway AirportChicago Midway Airport6:11 PMNiagara Falls AirportNiagara Falls Airport0EconomyA Flight from Frontier Airlines goes from Chicago Midway Airport, Chicago Midway Airport (USA) at 6/6/2026 11:59:00 AM to Niagara Falls Airport, Niagara Falls Airport (USA) arriving at 6/7/2026 6:11:00 PM. 50 Economy ticket for $229 per person are available. Travel duration is 29h 12m
Cheapest Buses Saturday
Cheapest Flights Saturday
-
Greyhound US13h 0m06:00 PMChicagoDowntown Bus Station8:00 AMBuffalo, NYCentral Bus Station0EconomyA Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 6/7/2026 6:00:00 PM to Central Bus Station, Buffalo, NY (USA) arriving at 6/8/2026 8:00:00 AM. 50 Economy ticket for $60 per person are available. Travel duration is 13h 0m
-
FlixBus20h 30m07:15 PMChicagoDowntown Bus Station4:45 PMBuffalo, NYCentral Bus Station0EconomyA Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 6/7/2026 7:15:00 PM to Central Bus Station, Buffalo, NY (USA) arriving at 6/8/2026 4:45:00 PM. 50 Economy ticket for $62 per person are available. Travel duration is 20h 30m
-
FlixBus13h 55m05:05 PMChicago95th Red Line Station8:00 AMBuffalo, NYCentral Bus Station0EconomyA Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 6/7/2026 5:05:00 PM to Central Bus Station, Buffalo, NY (USA) arriving at 6/8/2026 8:00:00 AM. 50 Economy ticket for $69 per person are available. Travel duration is 13h 55m
-
United Airlines1h 48m07:27 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center10:15 AMBuffalo AirportBuffalo Airport0EconomyA Flight from United Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/7/2026 7:27:00 AM to Buffalo Airport, Buffalo Airport (USA) arriving at 6/7/2026 10:15:00 AM. 50 Economy ticket for $193 per person are available. Travel duration is 1h 48m
-
United Airlines1h 46m01:55 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center4:41 PMBuffalo AirportBuffalo Airport0EconomyA Flight from United Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/7/2026 1:55:00 PM to Buffalo Airport, Buffalo Airport (USA) arriving at 6/7/2026 4:41:00 PM. 50 Economy ticket for $193 per person are available. Travel duration is 1h 46m
-
American Airlines1h 49m06:40 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center9:29 AMBuffalo AirportBuffalo Airport0EconomyA Flight from American Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/7/2026 6:40:00 AM to Buffalo Airport, Buffalo Airport (USA) arriving at 6/7/2026 9:29:00 AM. 50 Economy ticket for $195 per person are available. Travel duration is 1h 49m
-
Frontier Airlines23h 25m01:29 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center1:54 PMBuffalo AirportBuffalo Airport0EconomyA Flight from Frontier Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/7/2026 1:29:00 PM to Buffalo Airport, Buffalo Airport (USA) arriving at 6/8/2026 1:54:00 PM. 50 Economy ticket for $291 per person are available. Travel duration is 23h 25m
-
Frontier Airlines24h 27m012:27 PMChicago Midway AirportChicago Midway Airport1:54 PMBuffalo AirportBuffalo Airport0EconomyA Flight from Frontier Airlines goes from Chicago Midway Airport, Chicago Midway Airport (USA) at 6/7/2026 12:27:00 PM to Buffalo Airport, Buffalo Airport (USA) arriving at 6/8/2026 1:54:00 PM. 50 Economy ticket for $292 per person are available. Travel duration is 24h 27m
-
Allegiant Air30h 47m09:11 AMChicago Midway AirportChicago Midway Airport4:58 PMNiagara Falls AirportNiagara Falls Airport0EconomyA Flight from Allegiant Air goes from Chicago Midway Airport, Chicago Midway Airport (USA) at 6/7/2026 9:11:00 AM to Niagara Falls Airport, Niagara Falls Airport (USA) arriving at 6/8/2026 4:58:00 PM. 50 Economy ticket for $372 per person are available. Travel duration is 30h 47m
Cheapest Buses Sunday
Cheapest Flights Sunday
-
Greyhound US13h 0m06:00 PMChicagoDowntown Bus Station8:00 AMBuffalo, NYCentral Bus Station0EconomyA Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 6/8/2026 6:00:00 PM to Central Bus Station, Buffalo, NY (USA) arriving at 6/9/2026 8:00:00 AM. 50 Economy ticket for $56 per person are available. Travel duration is 13h 0m
-
FlixBus20h 30m07:15 PMChicagoDowntown Bus Station4:45 PMBuffalo, NYCentral Bus Station0EconomyA Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 6/8/2026 7:15:00 PM to Central Bus Station, Buffalo, NY (USA) arriving at 6/9/2026 4:45:00 PM. 50 Economy ticket for $56 per person are available. Travel duration is 20h 30m
-
FlixBus13h 55m05:05 PMChicago95th Red Line Station8:00 AMBuffalo, NYCentral Bus Station0EconomyA Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 6/8/2026 5:05:00 PM to Central Bus Station, Buffalo, NY (USA) arriving at 6/9/2026 8:00:00 AM. 50 Economy ticket for $62 per person are available. Travel duration is 13h 55m
-
Frontier Airlines22h 6m012:04 PMChicago Midway AirportChicago Midway Airport11:10 AMBuffalo AirportBuffalo Airport0EconomyA Flight from Frontier Airlines goes from Chicago Midway Airport, Chicago Midway Airport (USA) at 6/8/2026 12:04:00 PM to Buffalo Airport, Buffalo Airport (USA) arriving at 6/9/2026 11:10:00 AM. 50 Economy ticket for $143 per person are available. Travel duration is 22h 6m
-
United Airlines1h 46m06:17 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center9:03 PMBuffalo AirportBuffalo Airport0EconomyA Flight from United Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/8/2026 6:17:00 PM to Buffalo Airport, Buffalo Airport (USA) arriving at 6/8/2026 9:03:00 PM. 50 Economy ticket for $144 per person are available. Travel duration is 1h 46m
-
Skyscanner1h 48m07:27 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center10:15 AMBuffalo AirportBuffalo Airport0EconomyA Flight from Skyscanner goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/8/2026 7:27:00 AM to Buffalo Airport, Buffalo Airport (USA) arriving at 6/8/2026 10:15:00 AM. 50 Economy ticket for $260 per person are available. Travel duration is 1h 48m
-
United Airlines6h 0m03:40 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center10:40 PMBuffalo AirportBuffalo Airport0EconomyA Flight from United Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/8/2026 3:40:00 PM to Buffalo Airport, Buffalo Airport (USA) arriving at 6/8/2026 10:40:00 PM. 50 Economy ticket for $337 per person are available. Travel duration is 6h 0m
Cheapest Buses Monday
Cheapest Flights Monday
What are the fastest trips from Chicago to Buffalo, NY?
You can get to Buffalo, NY from Chicago in just 1h 46m with a Flight from United Airlines. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.
-
United Airlines1h 46m01:55 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center4:41 PMBuffalo AirportBuffalo Airport0EconomyA Flight from United Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/2/2026 1:55:00 PM to Buffalo Airport, Buffalo Airport (USA) arriving at 6/2/2026 4:41:00 PM. 50 Economy ticket for $118 per person are available. Travel duration is 1h 46m
-
United Airlines1h 46m06:17 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center9:03 PMBuffalo AirportBuffalo Airport0EconomyA Flight from United Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/2/2026 6:17:00 PM to Buffalo Airport, Buffalo Airport (USA) arriving at 6/2/2026 9:03:00 PM. 50 Economy ticket for $118 per person are available. Travel duration is 1h 46m
-
Skyscanner1h 48m07:27 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center10:15 AMBuffalo AirportBuffalo Airport0EconomyA Flight from Skyscanner goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/2/2026 7:27:00 AM to Buffalo Airport, Buffalo Airport (USA) arriving at 6/2/2026 10:15:00 AM. 50 Economy ticket for $161 per person are available. Travel duration is 1h 48m
-
Frontier Airlines24h 27m012:27 PMChicago Midway AirportChicago Midway Airport1:54 PMBuffalo AirportBuffalo Airport0EconomyA Flight from Frontier Airlines goes from Chicago Midway Airport, Chicago Midway Airport (USA) at 6/2/2026 12:27:00 PM to Buffalo Airport, Buffalo Airport (USA) arriving at 6/3/2026 1:54:00 PM. 50 Economy ticket for $67 per person are available. Travel duration is 24h 27m
-
Greyhound US13h 0m06:00 PMChicagoDowntown Bus Station8:00 AMBuffalo, NYCentral Bus Station0EconomyA Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 6/2/2026 6:00:00 PM to Central Bus Station, Buffalo, NY (USA) arriving at 6/3/2026 8:00:00 AM. 50 Economy ticket for $50 per person are available. Travel duration is 13h 0m
-
FlixBus20h 30m07:15 PMChicagoDowntown Bus Station4:45 PMBuffalo, NYCentral Bus Station0EconomyA Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 6/2/2026 7:15:00 PM to Central Bus Station, Buffalo, NY (USA) arriving at 6/3/2026 4:45:00 PM. 50 Economy ticket for $52 per person are available. Travel duration is 20h 30m
-
Greyhound US20h 45m010:15 AMChicagoCanal & Van Buren8:00 AMBuffalo, NYCentral Bus Station0EconomyA Bus from Greyhound US goes from Canal & Van Buren, Chicago (USA) at 6/2/2026 10:15:00 AM to Central Bus Station, Buffalo, NY (USA) arriving at 6/3/2026 8:00:00 AM. 50 Economy ticket for $54 per person are available. Travel duration is 20h 45m
Fastest Flights Tuesday
Fastest Buses Tuesday
-
United Airlines1h 46m06:17 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center9:03 PMBuffalo AirportBuffalo Airport0EconomyA Flight from United Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/3/2026 6:17:00 PM to Buffalo Airport, Buffalo Airport (USA) arriving at 6/3/2026 9:03:00 PM. 50 Economy ticket for $117 per person are available. Travel duration is 1h 46m
-
Skyscanner1h 48m07:27 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center10:15 AMBuffalo AirportBuffalo Airport0EconomyA Flight from Skyscanner goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/3/2026 7:27:00 AM to Buffalo Airport, Buffalo Airport (USA) arriving at 6/3/2026 10:15:00 AM. 50 Economy ticket for $117 per person are available. Travel duration is 1h 48m
-
United Airlines1h 48m07:27 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center10:15 AMBuffalo AirportBuffalo Airport0EconomyA Flight from United Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/3/2026 7:27:00 AM to Buffalo Airport, Buffalo Airport (USA) arriving at 6/3/2026 10:15:00 AM. 50 Economy ticket for $118 per person are available. Travel duration is 1h 48m
-
Frontier Airlines6h 54m06:00 AMChicago Midway AirportChicago Midway Airport1:54 PMBuffalo AirportBuffalo Airport0EconomyA Flight from Frontier Airlines goes from Chicago Midway Airport, Chicago Midway Airport (USA) at 6/3/2026 6:00:00 AM to Buffalo Airport, Buffalo Airport (USA) arriving at 6/3/2026 1:54:00 PM. 50 Economy ticket for $69 per person are available. Travel duration is 6h 54m
-
Frontier Airlines21h 37m012:04 PMChicago Midway AirportChicago Midway Airport10:41 AMBuffalo AirportBuffalo Airport0EconomyA Flight from Frontier Airlines goes from Chicago Midway Airport, Chicago Midway Airport (USA) at 6/3/2026 12:04:00 PM to Buffalo Airport, Buffalo Airport (USA) arriving at 6/4/2026 10:41:00 AM. 50 Economy ticket for $69 per person are available. Travel duration is 21h 37m
-
Frontier Airlines26h 4m03:07 PMChicago Midway AirportChicago Midway Airport6:11 PMNiagara Falls AirportNiagara Falls Airport0EconomyA Flight from Frontier Airlines goes from Chicago Midway Airport, Chicago Midway Airport (USA) at 6/3/2026 3:07:00 PM to Niagara Falls Airport, Niagara Falls Airport (USA) arriving at 6/4/2026 6:11:00 PM. 50 Economy ticket for $414 per person are available. Travel duration is 26h 4m
-
Greyhound US13h 0m06:00 PMChicagoDowntown Bus Station8:00 AMBuffalo, NYCentral Bus Station0EconomyA Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 6/3/2026 6:00:00 PM to Central Bus Station, Buffalo, NY (USA) arriving at 6/4/2026 8:00:00 AM. 50 Economy ticket for $52 per person are available. Travel duration is 13h 0m
-
FlixBus20h 30m07:15 PMChicagoDowntown Bus Station4:45 PMBuffalo, NYCentral Bus Station0EconomyA Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 6/3/2026 7:15:00 PM to Central Bus Station, Buffalo, NY (USA) arriving at 6/4/2026 4:45:00 PM. 50 Economy ticket for $52 per person are available. Travel duration is 20h 30m
-
Greyhound US20h 45m010:15 AMChicagoCanal & Van Buren8:00 AMBuffalo, NYCentral Bus Station0EconomyA Bus from Greyhound US goes from Canal & Van Buren, Chicago (USA) at 6/3/2026 10:15:00 AM to Central Bus Station, Buffalo, NY (USA) arriving at 6/4/2026 8:00:00 AM. 50 Economy ticket for $54 per person are available. Travel duration is 20h 45m
Fastest Flights Wednesday
Fastest Buses Wednesday
-
United Airlines1h 46m01:55 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center4:41 PMBuffalo AirportBuffalo Airport0EconomyA Flight from United Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/4/2026 1:55:00 PM to Buffalo Airport, Buffalo Airport (USA) arriving at 6/4/2026 4:41:00 PM. 50 Economy ticket for $173 per person are available. Travel duration is 1h 46m
-
United Airlines1h 46m06:17 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center9:03 PMBuffalo AirportBuffalo Airport0EconomyA Flight from United Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/4/2026 6:17:00 PM to Buffalo Airport, Buffalo Airport (USA) arriving at 6/4/2026 9:03:00 PM. 50 Economy ticket for $173 per person are available. Travel duration is 1h 46m
-
Skyscanner1h 48m07:27 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center10:15 AMBuffalo AirportBuffalo Airport0EconomyA Flight from Skyscanner goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/4/2026 7:27:00 AM to Buffalo Airport, Buffalo Airport (USA) arriving at 6/4/2026 10:15:00 AM. 50 Economy ticket for $173 per person are available. Travel duration is 1h 48m
-
Frontier Airlines23h 25m01:29 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center1:54 PMBuffalo AirportBuffalo Airport0EconomyA Flight from Frontier Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/4/2026 1:29:00 PM to Buffalo Airport, Buffalo Airport (USA) arriving at 6/5/2026 1:54:00 PM. 50 Economy ticket for $77 per person are available. Travel duration is 23h 25m
-
Frontier Airlines24h 27m012:27 PMChicago Midway AirportChicago Midway Airport1:54 PMBuffalo AirportBuffalo Airport0EconomyA Flight from Frontier Airlines goes from Chicago Midway Airport, Chicago Midway Airport (USA) at 6/4/2026 12:27:00 PM to Buffalo Airport, Buffalo Airport (USA) arriving at 6/5/2026 1:54:00 PM. 50 Economy ticket for $77 per person are available. Travel duration is 24h 27m
-
Allegiant Air30h 47m09:11 AMChicago Midway AirportChicago Midway Airport4:58 PMNiagara Falls AirportNiagara Falls Airport0EconomyA Flight from Allegiant Air goes from Chicago Midway Airport, Chicago Midway Airport (USA) at 6/4/2026 9:11:00 AM to Niagara Falls Airport, Niagara Falls Airport (USA) arriving at 6/5/2026 4:58:00 PM. 50 Economy ticket for $256 per person are available. Travel duration is 30h 47m
-
Greyhound US13h 0m06:00 PMChicagoDowntown Bus Station8:00 AMBuffalo, NYCentral Bus Station0EconomyA Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 6/4/2026 6:00:00 PM to Central Bus Station, Buffalo, NY (USA) arriving at 6/5/2026 8:00:00 AM. 50 Economy ticket for $56 per person are available. Travel duration is 13h 0m
-
FlixBus20h 30m07:15 PMChicagoDowntown Bus Station4:45 PMBuffalo, NYCentral Bus Station0EconomyA Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 6/4/2026 7:15:00 PM to Central Bus Station, Buffalo, NY (USA) arriving at 6/5/2026 4:45:00 PM. 50 Economy ticket for $55 per person are available. Travel duration is 20h 30m
-
Greyhound US20h 45m010:15 AMChicagoCanal & Van Buren8:00 AMBuffalo, NYCentral Bus Station0EconomyA Bus from Greyhound US goes from Canal & Van Buren, Chicago (USA) at 6/4/2026 10:15:00 AM to Central Bus Station, Buffalo, NY (USA) arriving at 6/5/2026 8:00:00 AM. 50 Economy ticket for $56 per person are available. Travel duration is 20h 45m
Fastest Flights Thursday
Fastest Buses Thursday
-
United Airlines1h 46m01:55 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center4:41 PMBuffalo AirportBuffalo Airport0EconomyA Flight from United Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/5/2026 1:55:00 PM to Buffalo Airport, Buffalo Airport (USA) arriving at 6/5/2026 4:41:00 PM. 50 Economy ticket for $173 per person are available. Travel duration is 1h 46m
-
United Airlines1h 46m06:17 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center9:03 PMBuffalo AirportBuffalo Airport0EconomyA Flight from United Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/5/2026 6:17:00 PM to Buffalo Airport, Buffalo Airport (USA) arriving at 6/5/2026 9:03:00 PM. 50 Economy ticket for $173 per person are available. Travel duration is 1h 46m
-
Frontier Airlines5h 59m06:55 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center1:54 PMBuffalo AirportBuffalo Airport0EconomyA Flight from Frontier Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/5/2026 6:55:00 AM to Buffalo Airport, Buffalo Airport (USA) arriving at 6/5/2026 1:54:00 PM. 50 Economy ticket for $111 per person are available. Travel duration is 5h 59m
-
Frontier Airlines6h 54m06:00 AMChicago Midway AirportChicago Midway Airport1:54 PMBuffalo AirportBuffalo Airport0EconomyA Flight from Frontier Airlines goes from Chicago Midway Airport, Chicago Midway Airport (USA) at 6/5/2026 6:00:00 AM to Buffalo Airport, Buffalo Airport (USA) arriving at 6/5/2026 1:54:00 PM. 50 Economy ticket for $114 per person are available. Travel duration is 6h 54m
-
JetBlue Airways7h 32m03:27 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center11:59 PMBuffalo AirportBuffalo Airport0EconomyA Flight from JetBlue Airways goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/5/2026 3:27:00 PM to Buffalo Airport, Buffalo Airport (USA) arriving at 6/5/2026 11:59:00 PM. 50 Economy ticket for $175 per person are available. Travel duration is 7h 32m
-
Greyhound US13h 0m06:00 PMChicagoDowntown Bus Station8:00 AMBuffalo, NYCentral Bus Station0EconomyA Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 6/5/2026 6:00:00 PM to Central Bus Station, Buffalo, NY (USA) arriving at 6/6/2026 8:00:00 AM. 50 Economy ticket for $60 per person are available. Travel duration is 13h 0m
-
FlixBus20h 30m07:15 PMChicagoDowntown Bus Station4:45 PMBuffalo, NYCentral Bus Station0EconomyA Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 6/5/2026 7:15:00 PM to Central Bus Station, Buffalo, NY (USA) arriving at 6/6/2026 4:45:00 PM. 50 Economy ticket for $60 per person are available. Travel duration is 20h 30m
-
Greyhound US20h 45m010:15 AMChicagoUnion Station8:00 AMBuffalo, NYCentral Bus Station0EconomyA Bus from Greyhound US goes from Union Station, Chicago (USA) at 6/5/2026 10:15:00 AM to Central Bus Station, Buffalo, NY (USA) arriving at 6/6/2026 8:00:00 AM. 50 Economy ticket for $80 per person are available. Travel duration is 20h 45m
Fastest Flights Friday
Fastest Buses Friday
-
United Airlines1h 46m01:55 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center4:41 PMBuffalo AirportBuffalo Airport0EconomyA Flight from United Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/6/2026 1:55:00 PM to Buffalo Airport, Buffalo Airport (USA) arriving at 6/6/2026 4:41:00 PM. 50 Economy ticket for $131 per person are available. Travel duration is 1h 46m
-
United Airlines1h 46m06:17 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center9:03 PMBuffalo AirportBuffalo Airport0EconomyA Flight from United Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/6/2026 6:17:00 PM to Buffalo Airport, Buffalo Airport (USA) arriving at 6/6/2026 9:03:00 PM. 50 Economy ticket for $131 per person are available. Travel duration is 1h 46m
-
Skyscanner1h 48m07:27 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center10:15 AMBuffalo AirportBuffalo Airport0EconomyA Flight from Skyscanner goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/6/2026 7:27:00 AM to Buffalo Airport, Buffalo Airport (USA) arriving at 6/6/2026 10:15:00 AM. 50 Economy ticket for $131 per person are available. Travel duration is 1h 48m
-
Frontier Airlines21h 42m011:59 AMChicago Midway AirportChicago Midway Airport10:41 AMBuffalo AirportBuffalo Airport0EconomyA Flight from Frontier Airlines goes from Chicago Midway Airport, Chicago Midway Airport (USA) at 6/6/2026 11:59:00 AM to Buffalo Airport, Buffalo Airport (USA) arriving at 6/7/2026 10:41:00 AM. 50 Economy ticket for $119 per person are available. Travel duration is 21h 42m
-
Frontier Airlines23h 34m05:37 PMChicago Midway AirportChicago Midway Airport6:11 PMNiagara Falls AirportNiagara Falls Airport0EconomyA Flight from Frontier Airlines goes from Chicago Midway Airport, Chicago Midway Airport (USA) at 6/6/2026 5:37:00 PM to Niagara Falls Airport, Niagara Falls Airport (USA) arriving at 6/7/2026 6:11:00 PM. 50 Economy ticket for $404 per person are available. Travel duration is 23h 34m
-
Frontier Airlines27h 42m01:29 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center6:11 PMNiagara Falls AirportNiagara Falls Airport0EconomyA Flight from Frontier Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/6/2026 1:29:00 PM to Niagara Falls Airport, Niagara Falls Airport (USA) arriving at 6/7/2026 6:11:00 PM. 50 Economy ticket for $209 per person are available. Travel duration is 27h 42m
-
Greyhound US13h 0m06:00 PMChicagoDowntown Bus Station8:00 AMBuffalo, NYCentral Bus Station0EconomyA Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 6/6/2026 6:00:00 PM to Central Bus Station, Buffalo, NY (USA) arriving at 6/7/2026 8:00:00 AM. 50 Economy ticket for $58 per person are available. Travel duration is 13h 0m
-
FlixBus20h 30m07:15 PMChicagoDowntown Bus Station4:45 PMBuffalo, NYCentral Bus Station0EconomyA Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 6/6/2026 7:15:00 PM to Central Bus Station, Buffalo, NY (USA) arriving at 6/7/2026 4:45:00 PM. 50 Economy ticket for $58 per person are available. Travel duration is 20h 30m
-
Greyhound US20h 45m010:15 AMChicagoCanal & Van Buren8:00 AMBuffalo, NYCentral Bus Station0EconomyA Bus from Greyhound US goes from Canal & Van Buren, Chicago (USA) at 6/6/2026 10:15:00 AM to Central Bus Station, Buffalo, NY (USA) arriving at 6/7/2026 8:00:00 AM. 50 Economy ticket for $58 per person are available. Travel duration is 20h 45m
Fastest Flights Saturday
Fastest Buses Saturday
-
United Airlines1h 46m01:55 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center4:41 PMBuffalo AirportBuffalo Airport0EconomyA Flight from United Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/7/2026 1:55:00 PM to Buffalo Airport, Buffalo Airport (USA) arriving at 6/7/2026 4:41:00 PM. 50 Economy ticket for $193 per person are available. Travel duration is 1h 46m
-
United Airlines1h 48m07:27 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center10:15 AMBuffalo AirportBuffalo Airport0EconomyA Flight from United Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/7/2026 7:27:00 AM to Buffalo Airport, Buffalo Airport (USA) arriving at 6/7/2026 10:15:00 AM. 50 Economy ticket for $193 per person are available. Travel duration is 1h 48m
-
American Airlines1h 49m06:40 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center9:29 AMBuffalo AirportBuffalo Airport0EconomyA Flight from American Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/7/2026 6:40:00 AM to Buffalo Airport, Buffalo Airport (USA) arriving at 6/7/2026 9:29:00 AM. 50 Economy ticket for $195 per person are available. Travel duration is 1h 49m
-
Frontier Airlines23h 25m01:29 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center1:54 PMBuffalo AirportBuffalo Airport0EconomyA Flight from Frontier Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/7/2026 1:29:00 PM to Buffalo Airport, Buffalo Airport (USA) arriving at 6/8/2026 1:54:00 PM. 50 Economy ticket for $291 per person are available. Travel duration is 23h 25m
-
Frontier Airlines24h 27m012:27 PMChicago Midway AirportChicago Midway Airport1:54 PMBuffalo AirportBuffalo Airport0EconomyA Flight from Frontier Airlines goes from Chicago Midway Airport, Chicago Midway Airport (USA) at 6/7/2026 12:27:00 PM to Buffalo Airport, Buffalo Airport (USA) arriving at 6/8/2026 1:54:00 PM. 50 Economy ticket for $292 per person are available. Travel duration is 24h 27m
-
Allegiant Air30h 47m09:11 AMChicago Midway AirportChicago Midway Airport4:58 PMNiagara Falls AirportNiagara Falls Airport0EconomyA Flight from Allegiant Air goes from Chicago Midway Airport, Chicago Midway Airport (USA) at 6/7/2026 9:11:00 AM to Niagara Falls Airport, Niagara Falls Airport (USA) arriving at 6/8/2026 4:58:00 PM. 50 Economy ticket for $372 per person are available. Travel duration is 30h 47m
-
Greyhound US13h 0m06:00 PMChicagoDowntown Bus Station8:00 AMBuffalo, NYCentral Bus Station0EconomyA Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 6/7/2026 6:00:00 PM to Central Bus Station, Buffalo, NY (USA) arriving at 6/8/2026 8:00:00 AM. 50 Economy ticket for $60 per person are available. Travel duration is 13h 0m
-
FlixBus13h 55m05:05 PMChicago95th Red Line Station8:00 AMBuffalo, NYCentral Bus Station0EconomyA Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 6/7/2026 5:05:00 PM to Central Bus Station, Buffalo, NY (USA) arriving at 6/8/2026 8:00:00 AM. 50 Economy ticket for $69 per person are available. Travel duration is 13h 55m
-
FlixBus20h 30m07:15 PMChicagoDowntown Bus Station4:45 PMBuffalo, NYCentral Bus Station0EconomyA Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 6/7/2026 7:15:00 PM to Central Bus Station, Buffalo, NY (USA) arriving at 6/8/2026 4:45:00 PM. 50 Economy ticket for $62 per person are available. Travel duration is 20h 30m
Fastest Flights Sunday
Fastest Buses Sunday
-
United Airlines1h 46m06:17 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center9:03 PMBuffalo AirportBuffalo Airport0EconomyA Flight from United Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/8/2026 6:17:00 PM to Buffalo Airport, Buffalo Airport (USA) arriving at 6/8/2026 9:03:00 PM. 50 Economy ticket for $144 per person are available. Travel duration is 1h 46m
-
Skyscanner1h 48m07:27 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center10:15 AMBuffalo AirportBuffalo Airport0EconomyA Flight from Skyscanner goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/8/2026 7:27:00 AM to Buffalo Airport, Buffalo Airport (USA) arriving at 6/8/2026 10:15:00 AM. 50 Economy ticket for $260 per person are available. Travel duration is 1h 48m
-
United Airlines6h 0m03:40 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center10:40 PMBuffalo AirportBuffalo Airport0EconomyA Flight from United Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/8/2026 3:40:00 PM to Buffalo Airport, Buffalo Airport (USA) arriving at 6/8/2026 10:40:00 PM. 50 Economy ticket for $337 per person are available. Travel duration is 6h 0m
-
Frontier Airlines22h 6m012:04 PMChicago Midway AirportChicago Midway Airport11:10 AMBuffalo AirportBuffalo Airport0EconomyA Flight from Frontier Airlines goes from Chicago Midway Airport, Chicago Midway Airport (USA) at 6/8/2026 12:04:00 PM to Buffalo Airport, Buffalo Airport (USA) arriving at 6/9/2026 11:10:00 AM. 50 Economy ticket for $143 per person are available. Travel duration is 22h 6m
-
Greyhound US13h 0m06:00 PMChicagoDowntown Bus Station8:00 AMBuffalo, NYCentral Bus Station0EconomyA Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 6/8/2026 6:00:00 PM to Central Bus Station, Buffalo, NY (USA) arriving at 6/9/2026 8:00:00 AM. 50 Economy ticket for $56 per person are available. Travel duration is 13h 0m
-
FlixBus13h 55m05:05 PMChicago95th Red Line Station8:00 AMBuffalo, NYCentral Bus Station0EconomyA Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 6/8/2026 5:05:00 PM to Central Bus Station, Buffalo, NY (USA) arriving at 6/9/2026 8:00:00 AM. 50 Economy ticket for $62 per person are available. Travel duration is 13h 55m
-
FlixBus20h 30m07:15 PMChicagoDowntown Bus Station4:45 PMBuffalo, NYCentral Bus Station0EconomyA Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 6/8/2026 7:15:00 PM to Central Bus Station, Buffalo, NY (USA) arriving at 6/9/2026 4:45:00 PM. 50 Economy ticket for $56 per person are available. Travel duration is 20h 30m
Fastest Flights Monday
Fastest Buses Monday
Here you will find all operators and timetables for a
Bus from Chicago to Buffalo, NY
What are the most popular stations in Chicago and Buffalo, NY?
In Chicago, you will usually depart from California & 35th Street Bus Stop, Downtown Bus Station or 95th Red Line Station, while in Buffalo, NY you will be arriving at Exchange Street Train Station, Maple Road Gulf or Central Bus Station, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Buffalo, NY from Chicago? With 11 connections between 2 Flight and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Chicago and Buffalo, NY, you can pay as low as $50 with a Bus from Greyhound US.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from United Airlines: you will get to Buffalo, NY in just 1h 46m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Chicago and Buffalo, NY are Frontier Airlines, Greyhound US and FlixBus, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Chicago and Buffalo, NY is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Cicero, IL or to Sloan, NY, and look at flights from Chicago Midway Airport, and landing at Niagara Falls Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Chicago to Buffalo, NY?
The most popular companies between Chicago and Buffalo, NY, are Frontier Airlines, Greyhound US and FlixBus. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: Greyhound US and FlixBus
Airlines: Frontier Airlines, United Airlines, Skyscanner and 3 more.
All you need to know when you travel from Chicago to Buffalo, NY
Check all information on comfort and services on all modes of transports from Chicago to Buffalo, NY. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Chicago to Buffalo, NY
How can I reach Buffalo, NY from Chicago?
Every day, there are on average 11 connections between Flight and Bus, with which you can get to Buffalo, NY from Chicago.
How far is Buffalo, NY from Chicago?
The distance between Chicago and Buffalo, NY is 452.7 miles.
What is the most ecofriendly mode of transport between Chicago and Buffalo, NY?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 20 kgs of CO2, a train 26 kgs, a car 124 kgs, and a flight 179 kgs.
What is the cheapest mode of transport from Chicago to Buffalo, NY?
You can get to Buffalo, NY with just $50 by taking a Bus from Greyhound US.
What is the fastest way to get from Chicago to Buffalo, NY?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Buffalo, NY in just 1h 46m with a Flight from United Airlines.
More routes to Chicago and to Buffalo, NY
Looking for more options? Here you can see the most popular routes to Chicago and to Buffalo, NY. Simply click on a connection, and you’ll find all the details about the route!
