What is the best way to travel from Frankfurt am Main to Prague?
Looking for a trip? Compare all the available Buses and Flights for the journey to Prague from Frankfurt am Main. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 1 available companies to find your perfect trip!
What is the cheapest way to reach Prague from Frankfurt am Main?
You can get to Prague with just $53 by taking a Bus from RegioJet, but you can find many more cheap offers: we have selected the best ones for next few days here for you.
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FlixBus8h 55m09:00 AMFrankfurt am MainCentral Station5:55 PMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/24/2025 9:00:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 12/24/2025 5:55:00 PM. 50 Economy ticket for $68 per person are available. Travel duration is 8h 55m
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FlixBus8h 20m011:15 AMFrankfurt am MainCentral Station7:35 PMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/24/2025 11:15:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 12/24/2025 7:35:00 PM. 50 Economy ticket for $68 per person are available. Travel duration is 8h 20m
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FlixBus8h 30m01:00 PMFrankfurt am MainCentral Station9:30 PMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/24/2025 1:00:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 12/24/2025 9:30:00 PM. 50 Economy ticket for $68 per person are available. Travel duration is 8h 30m
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FlixBus7h 55m011:15 AMFrankfurt am MainCentral Station7:10 PMPragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/24/2025 11:15:00 AM to Na Knížecí Station, Prague (Czech Republic) arriving at 12/24/2025 7:10:00 PM. 50 Economy ticket for $68 per person are available. Travel duration is 7h 55m
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FlixBus8h 10m01:00 PMFrankfurt am MainCentral Station9:10 PMPragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/24/2025 1:00:00 PM to Na Knížecí Station, Prague (Czech Republic) arriving at 12/24/2025 9:10:00 PM. 50 Economy ticket for $68 per person are available. Travel duration is 8h 10m
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Condor1h 0m09:20 AMFrankfurt am Main AirportFrankfurt am Main Airport10:20 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/24/2025 9:20:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/24/2025 10:20:00 AM. 50 Economy ticket for $159 per person are available. Travel duration is 1h 0m
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Condor1h 0m08:10 PMFrankfurt am Main AirportFrankfurt am Main Airport9:10 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/24/2025 8:10:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/24/2025 9:10:00 PM. 50 Economy ticket for $159 per person are available. Travel duration is 1h 0m
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Air Dolomiti1h 5m08:30 AMFrankfurt am Main AirportFrankfurt am Main Airport9:35 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Air Dolomiti goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/24/2025 8:30:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/24/2025 9:35:00 AM. 50 Economy ticket for $249 per person are available. Travel duration is 1h 5m
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Lufthansa1h 5m010:20 AMFrankfurt am Main AirportFrankfurt am Main Airport11:25 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/24/2025 10:20:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/24/2025 11:25:00 AM. 50 Economy ticket for $249 per person are available. Travel duration is 1h 5m
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Lufthansa1h 5m01:00 PMFrankfurt am Main AirportFrankfurt am Main Airport2:05 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/24/2025 1:00:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/24/2025 2:05:00 PM. 50 Economy ticket for $524 per person are available. Travel duration is 1h 5m
Cheapest Buses Wednesday
Cheapest Flights Wednesday
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FlixBus8h 10m01:00 PMFrankfurt am MainCentral Station9:10 PMPragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/25/2025 1:00:00 PM to Na Knížecí Station, Prague (Czech Republic) arriving at 12/25/2025 9:10:00 PM. 50 Economy ticket for $66 per person are available. Travel duration is 8h 10m
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FlixBus8h 30m01:00 PMFrankfurt am MainCentral Station9:30 PMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/25/2025 1:00:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 12/25/2025 9:30:00 PM. 50 Economy ticket for $66 per person are available. Travel duration is 8h 30m
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FlixBus6h 56m011:59 PMFrankfurt am MainCentral Station6:55 AMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/25/2025 11:59:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 12/26/2025 6:55:00 AM. 50 Economy ticket for $66 per person are available. Travel duration is 6h 56m
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FlixBus7h 55m011:15 AMFrankfurt am MainCentral Station7:10 PMPragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/25/2025 11:15:00 AM to Na Knížecí Station, Prague (Czech Republic) arriving at 12/25/2025 7:10:00 PM. 50 Economy ticket for $68 per person are available. Travel duration is 7h 55m
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FlixBus7h 25m05:45 AMFrankfurt am MainCentral Station1:10 PMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/25/2025 5:45:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 12/25/2025 1:10:00 PM. 50 Economy ticket for $68 per person are available. Travel duration is 7h 25m
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Condor1h 0m02:15 PMFrankfurt am Main AirportFrankfurt am Main Airport3:15 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/25/2025 2:15:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/25/2025 3:15:00 PM. 50 Economy ticket for $162 per person are available. Travel duration is 1h 0m
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Condor1h 0m08:10 PMFrankfurt am Main AirportFrankfurt am Main Airport9:10 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/25/2025 8:10:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/25/2025 9:10:00 PM. 50 Economy ticket for $182 per person are available. Travel duration is 1h 0m
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Lufthansa1h 5m09:20 PMFrankfurt am Main AirportFrankfurt am Main Airport10:25 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/25/2025 9:20:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/25/2025 10:25:00 PM. 50 Economy ticket for $248 per person are available. Travel duration is 1h 5m
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Lufthansa1h 5m01:00 PMFrankfurt am Main AirportFrankfurt am Main Airport2:05 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/25/2025 1:00:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/25/2025 2:05:00 PM. 50 Economy ticket for $366 per person are available. Travel duration is 1h 5m
Cheapest Buses Thursday
Cheapest Flights Thursday
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FlixBus7h 20m05:05 PMFrankfurt am MainCentral Station12:25 AMPragueWilsonova Bus Station0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/26/2025 5:05:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 12/27/2025 12:25:00 AM. 50 Economy ticket for $64 per person are available. Travel duration is 7h 20m
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FlixBus7h 0m05:05 PMFrankfurt am MainCentral Station12:05 AMPragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/26/2025 5:05:00 PM to Na Knížecí Station, Prague (Czech Republic) arriving at 12/27/2025 12:05:00 AM. 50 Economy ticket for $64 per person are available. Travel duration is 7h 0m
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FlixBus6h 56m011:59 PMFrankfurt am MainCentral Station6:55 AMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/26/2025 11:59:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 12/27/2025 6:55:00 AM. 50 Economy ticket for $66 per person are available. Travel duration is 6h 56m
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FlixBus8h 56m011:59 PMFrankfurt am MainCentral Station8:55 AMPragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/26/2025 11:59:00 PM to Na Knížecí Station, Prague (Czech Republic) arriving at 12/27/2025 8:55:00 AM. 50 Economy ticket for $67 per person are available. Travel duration is 8h 56m
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FlixBus8h 15m01:50 AMFrankfurt am MainCentral Station10:05 AMPragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/26/2025 1:50:00 AM to Na Knížecí Station, Prague (Czech Republic) arriving at 12/26/2025 10:05:00 AM. 50 Economy ticket for $70 per person are available. Travel duration is 8h 15m
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Condor1h 0m09:20 AMFrankfurt am Main AirportFrankfurt am Main Airport10:20 AMPrague AirportPrague Airport0EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/26/2025 9:20:00 AM to Prague Airport, Prague Airport (Czech Republic) arriving at 12/26/2025 10:20:00 AM. 50 Economy ticket for $217 per person are available. Travel duration is 1h 0m
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Air Serbia9h 50m09:55 AMFrankfurt am Main AirportFrankfurt am Main Airport7:45 PMPrague AirportPrague Airport0EconomyA Flight from Air Serbia goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/26/2025 9:55:00 AM to Prague Airport, Prague Airport (Czech Republic) arriving at 12/26/2025 7:45:00 PM. 50 Economy ticket for $262 per person are available. Travel duration is 9h 50m
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Lufthansa9h 5m012:50 PMFrankfurt am Main AirportFrankfurt am Main Airport9:55 PMPrague AirportPrague Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/26/2025 12:50:00 PM to Prague Airport, Prague Airport (Czech Republic) arriving at 12/26/2025 9:55:00 PM. 50 Economy ticket for $270 per person are available. Travel duration is 9h 5m
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EasyJet Airline11h 25m09:10 AMFrankfurt am Main AirportFrankfurt am Main Airport8:35 PMPrague AirportPrague Airport0EconomyA Flight from EasyJet Airline goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/26/2025 9:10:00 AM to Prague Airport, Prague Airport (Czech Republic) arriving at 12/26/2025 8:35:00 PM. 50 Economy ticket for $333 per person are available. Travel duration is 11h 25m
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Pegasus Group LTD17h 35m03:35 PMFrankfurt am Main AirportFrankfurt am Main Airport9:10 AMPrague AirportPrague Airport0EconomyA Flight from Pegasus Group LTD goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/26/2025 3:35:00 PM to Prague Airport, Prague Airport (Czech Republic) arriving at 12/27/2025 9:10:00 AM. 50 Economy ticket for $336 per person are available. Travel duration is 17h 35m
Cheapest Buses Friday
Cheapest Flights Friday
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FlixBus7h 20m05:05 PMFrankfurt am MainCentral Station12:25 AMPragueWilsonova Bus Station0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/27/2025 5:05:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 12/28/2025 12:25:00 AM. 50 Economy ticket for $66 per person are available. Travel duration is 7h 20m
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FlixBus7h 0m05:05 PMFrankfurt am MainCentral Station12:05 AMPragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/27/2025 5:05:00 PM to Na Knížecí Station, Prague (Czech Republic) arriving at 12/28/2025 12:05:00 AM. 50 Economy ticket for $66 per person are available. Travel duration is 7h 0m
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FlixBus9h 45m08:15 PMFrankfurt am MainCentral Station6:00 AMPragueWilsonova Bus Station0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/27/2025 8:15:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 12/28/2025 6:00:00 AM. 50 Economy ticket for $68 per person are available. Travel duration is 9h 45m
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FlixBus8h 56m011:59 PMFrankfurt am MainCentral Station8:55 AMPragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/27/2025 11:59:00 PM to Na Knížecí Station, Prague (Czech Republic) arriving at 12/28/2025 8:55:00 AM. 50 Economy ticket for $68 per person are available. Travel duration is 8h 56m
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FlixBus8h 55m09:00 AMFrankfurt am MainCentral Station5:55 PMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/27/2025 9:00:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 12/27/2025 5:55:00 PM. 50 Economy ticket for $68 per person are available. Travel duration is 8h 55m
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Condor1h 0m09:20 AMFrankfurt am Main AirportFrankfurt am Main Airport10:20 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/27/2025 9:20:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/27/2025 10:20:00 AM. 50 Economy ticket for $208 per person are available. Travel duration is 1h 0m
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Condor1h 0m02:15 PMFrankfurt am Main AirportFrankfurt am Main Airport3:15 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/27/2025 2:15:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/27/2025 3:15:00 PM. 50 Economy ticket for $335 per person are available. Travel duration is 1h 0m
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Air Dolomiti1h 5m08:45 AMFrankfurt am Main AirportFrankfurt am Main Airport9:50 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Air Dolomiti goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/27/2025 8:45:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/27/2025 9:50:00 AM. 50 Economy ticket for $360 per person are available. Travel duration is 1h 5m
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Lufthansa1h 5m09:20 PMFrankfurt am Main AirportFrankfurt am Main Airport10:25 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/27/2025 9:20:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/27/2025 10:25:00 PM. 50 Economy ticket for $498 per person are available. Travel duration is 1h 5m
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Air Dolomiti1h 5m05:10 PMFrankfurt am Main AirportFrankfurt am Main Airport6:15 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Air Dolomiti goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/27/2025 5:10:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/27/2025 6:15:00 PM. 50 Economy ticket for $532 per person are available. Travel duration is 1h 5m
Cheapest Buses Saturday
Cheapest Flights Saturday
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RegioJet6h 45m010:00 PMFrankfurt am Main AirportFrankfurt am Main Airport4:45 AMPragueTrain station Wilsonova0EconomyA Bus from RegioJet goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/28/2025 10:00:00 PM to Train station Wilsonova, Prague (Czech Republic) arriving at 12/29/2025 4:45:00 AM. 50 Economy ticket for $53 per person are available. Travel duration is 6h 45m
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RegioJet6h 48m010:00 PMFrankfurt am Main AirportFrankfurt am Main Airport4:48 AMPragueÚAN Florenc0EconomyA Bus from RegioJet goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/28/2025 10:00:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 12/29/2025 4:48:00 AM. 50 Economy ticket for $53 per person are available. Travel duration is 6h 48m
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FlixBus7h 20m05:05 PMFrankfurt am MainCentral Station12:25 AMPragueWilsonova Bus Station0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/28/2025 5:05:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 12/29/2025 12:25:00 AM. 50 Economy ticket for $66 per person are available. Travel duration is 7h 20m
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FlixBus7h 0m05:05 PMFrankfurt am MainCentral Station12:05 AMPragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/28/2025 5:05:00 PM to Na Knížecí Station, Prague (Czech Republic) arriving at 12/29/2025 12:05:00 AM. 50 Economy ticket for $66 per person are available. Travel duration is 7h 0m
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FlixBus7h 0m03:20 PMFrankfurt am MainCentral Station10:20 PMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/28/2025 3:20:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 12/28/2025 10:20:00 PM. 50 Economy ticket for $68 per person are available. Travel duration is 7h 0m
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Condor1h 0m09:20 AMFrankfurt am Main AirportFrankfurt am Main Airport10:20 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/28/2025 9:20:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/28/2025 10:20:00 AM. 50 Economy ticket for $162 per person are available. Travel duration is 1h 0m
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Lufthansa1h 5m09:10 PMFrankfurt am Main AirportFrankfurt am Main Airport10:15 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/28/2025 9:10:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/28/2025 10:15:00 PM. 50 Economy ticket for $243 per person are available. Travel duration is 1h 5m
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Air Dolomiti1h 5m08:45 AMFrankfurt am Main AirportFrankfurt am Main Airport9:50 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Air Dolomiti goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/28/2025 8:45:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/28/2025 9:50:00 AM. 50 Economy ticket for $253 per person are available. Travel duration is 1h 5m
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Austrian Airlines3h 10m012:50 PMFrankfurt am Main AirportFrankfurt am Main Airport4:00 PMPrague AirportPrague Airport0EconomyA Flight from Austrian Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/28/2025 12:50:00 PM to Prague Airport, Prague Airport (Czech Republic) arriving at 12/28/2025 4:00:00 PM. 50 Economy ticket for $307 per person are available. Travel duration is 3h 10m
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EasyJet Airline8h 10m09:10 AMFrankfurt am Main AirportFrankfurt am Main Airport5:20 PMPrague AirportPrague Airport0EconomyA Flight from EasyJet Airline goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/28/2025 9:10:00 AM to Prague Airport, Prague Airport (Czech Republic) arriving at 12/28/2025 5:20:00 PM. 50 Economy ticket for $319 per person are available. Travel duration is 8h 10m
Cheapest Buses Sunday
Cheapest Flights Sunday
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FlixBus9h 50m06:10 AMFrankfurt am MainCentral Station4:00 PMPragueWilsonova Bus Station0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/29/2025 6:10:00 AM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 12/29/2025 4:00:00 PM. 50 Economy ticket for $57 per person are available. Travel duration is 9h 50m
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FlixBus8h 56m011:59 PMFrankfurt am MainCentral Station8:55 AMPragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/29/2025 11:59:00 PM to Na Knížecí Station, Prague (Czech Republic) arriving at 12/30/2025 8:55:00 AM. 50 Economy ticket for $57 per person are available. Travel duration is 8h 56m
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FlixBus9h 0m01:50 AMFrankfurt am MainCentral Station10:50 AMPragueWilsonova Bus Station0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/29/2025 1:50:00 AM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 12/29/2025 10:50:00 AM. 50 Economy ticket for $64 per person are available. Travel duration is 9h 0m
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FlixBus8h 15m01:50 AMFrankfurt am MainCentral Station10:05 AMPragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/29/2025 1:50:00 AM to Na Knížecí Station, Prague (Czech Republic) arriving at 12/29/2025 10:05:00 AM. 50 Economy ticket for $64 per person are available. Travel duration is 8h 15m
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FlixBus7h 30m01:50 AMFrankfurt am MainCentral Station9:20 AMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/29/2025 1:50:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 12/29/2025 9:20:00 AM. 50 Economy ticket for $64 per person are available. Travel duration is 7h 30m
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Condor1h 0m02:15 PMFrankfurt am Main AirportFrankfurt am Main Airport3:15 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/29/2025 2:15:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/29/2025 3:15:00 PM. 50 Economy ticket for $180 per person are available. Travel duration is 1h 0m
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Lufthansa1h 5m09:20 PMFrankfurt am Main AirportFrankfurt am Main Airport10:25 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/29/2025 9:20:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/29/2025 10:25:00 PM. 50 Economy ticket for $216 per person are available. Travel duration is 1h 5m
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Air Dolomiti1h 5m05:10 PMFrankfurt am Main AirportFrankfurt am Main Airport6:15 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Air Dolomiti goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/29/2025 5:10:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/29/2025 6:15:00 PM. 50 Economy ticket for $257 per person are available. Travel duration is 1h 5m
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Air Serbia22h 40m09:55 AMFrankfurt am Main AirportFrankfurt am Main Airport8:35 AMPrague AirportPrague Airport0EconomyA Flight from Air Serbia goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/29/2025 9:55:00 AM to Prague Airport, Prague Airport (Czech Republic) arriving at 12/30/2025 8:35:00 AM. 50 Economy ticket for $262 per person are available. Travel duration is 22h 40m
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EasyJet Airline7h 20m09:10 AMFrankfurt am Main AirportFrankfurt am Main Airport4:30 PMPrague AirportPrague Airport0EconomyA Flight from EasyJet Airline goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/29/2025 9:10:00 AM to Prague Airport, Prague Airport (Czech Republic) arriving at 12/29/2025 4:30:00 PM. 50 Economy ticket for $297 per person are available. Travel duration is 7h 20m
Cheapest Buses Monday
Cheapest Flights Monday
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FlixBus9h 0m01:50 AMFrankfurt am MainCentral Station10:50 AMPragueWilsonova Bus Station0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/30/2025 1:50:00 AM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 12/30/2025 10:50:00 AM. 50 Economy ticket for $55 per person are available. Travel duration is 9h 0m
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FlixBus9h 45m08:15 PMFrankfurt am MainCentral Station6:00 AMPragueWilsonova Bus Station0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/30/2025 8:15:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 12/31/2025 6:00:00 AM. 50 Economy ticket for $55 per person are available. Travel duration is 9h 45m
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FlixBus8h 15m01:50 AMFrankfurt am MainCentral Station10:05 AMPragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/30/2025 1:50:00 AM to Na Knížecí Station, Prague (Czech Republic) arriving at 12/30/2025 10:05:00 AM. 50 Economy ticket for $55 per person are available. Travel duration is 8h 15m
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FlixBus9h 50m02:50 AMFrankfurt am MainCentral Station12:40 PMPragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/30/2025 2:50:00 AM to Na Knížecí Station, Prague (Czech Republic) arriving at 12/30/2025 12:40:00 PM. 50 Economy ticket for $55 per person are available. Travel duration is 9h 50m
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FlixBus8h 56m011:59 PMFrankfurt am MainCentral Station8:55 AMPragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/30/2025 11:59:00 PM to Na Knížecí Station, Prague (Czech Republic) arriving at 12/31/2025 8:55:00 AM. 50 Economy ticket for $55 per person are available. Travel duration is 8h 56m
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Condor1h 0m09:20 AMFrankfurt am Main AirportFrankfurt am Main Airport10:20 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/30/2025 9:20:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/30/2025 10:20:00 AM. 50 Economy ticket for $163 per person are available. Travel duration is 1h 0m
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Ryanair13h 0m07:50 PMFrankfurt am Main AirportFrankfurt am Main Airport8:50 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Ryanair goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/30/2025 7:50:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/31/2025 8:50:00 AM. 50 Economy ticket for $173 per person are available. Travel duration is 13h 0m
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Ryanair17h 50m04:35 PMFrankfurt am Main AirportFrankfurt am Main Airport10:25 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Ryanair goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/30/2025 4:35:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/31/2025 10:25:00 AM. 50 Economy ticket for $187 per person are available. Travel duration is 17h 50m
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Condor1h 0m02:15 PMFrankfurt am Main AirportFrankfurt am Main Airport3:15 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/30/2025 2:15:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/30/2025 3:15:00 PM. 50 Economy ticket for $211 per person are available. Travel duration is 1h 0m
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Air Dolomiti1h 5m08:30 AMFrankfurt am Main AirportFrankfurt am Main Airport9:35 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Air Dolomiti goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/30/2025 8:30:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/30/2025 9:35:00 AM. 50 Economy ticket for $236 per person are available. Travel duration is 1h 5m
Cheapest Buses Tuesday
Cheapest Flights Tuesday
What are the fastest trips from Frankfurt am Main to Prague?
You can get to Prague from Frankfurt am Main in just 1h 0m with a Flight from Condor. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.
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Condor1h 0m09:20 AMFrankfurt am Main AirportFrankfurt am Main Airport10:20 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/24/2025 9:20:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/24/2025 10:20:00 AM. 50 Economy ticket for $159 per person are available. Travel duration is 1h 0m
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Condor1h 0m08:10 PMFrankfurt am Main AirportFrankfurt am Main Airport9:10 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/24/2025 8:10:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/24/2025 9:10:00 PM. 50 Economy ticket for $159 per person are available. Travel duration is 1h 0m
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Air Dolomiti1h 5m08:30 AMFrankfurt am Main AirportFrankfurt am Main Airport9:35 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Air Dolomiti goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/24/2025 8:30:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/24/2025 9:35:00 AM. 50 Economy ticket for $249 per person are available. Travel duration is 1h 5m
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Lufthansa1h 5m010:20 AMFrankfurt am Main AirportFrankfurt am Main Airport11:25 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/24/2025 10:20:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/24/2025 11:25:00 AM. 50 Economy ticket for $249 per person are available. Travel duration is 1h 5m
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Lufthansa1h 5m01:00 PMFrankfurt am Main AirportFrankfurt am Main Airport2:05 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/24/2025 1:00:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/24/2025 2:05:00 PM. 50 Economy ticket for $524 per person are available. Travel duration is 1h 5m
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FlixBus7h 55m011:15 AMFrankfurt am MainCentral Station7:10 PMPragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/24/2025 11:15:00 AM to Na Knížecí Station, Prague (Czech Republic) arriving at 12/24/2025 7:10:00 PM. 50 Economy ticket for $68 per person are available. Travel duration is 7h 55m
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FlixBus8h 10m01:00 PMFrankfurt am MainCentral Station9:10 PMPragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/24/2025 1:00:00 PM to Na Knížecí Station, Prague (Czech Republic) arriving at 12/24/2025 9:10:00 PM. 50 Economy ticket for $68 per person are available. Travel duration is 8h 10m
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FlixBus8h 20m011:15 AMFrankfurt am MainCentral Station7:35 PMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/24/2025 11:15:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 12/24/2025 7:35:00 PM. 50 Economy ticket for $68 per person are available. Travel duration is 8h 20m
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FlixBus8h 30m01:00 PMFrankfurt am MainCentral Station9:30 PMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/24/2025 1:00:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 12/24/2025 9:30:00 PM. 50 Economy ticket for $68 per person are available. Travel duration is 8h 30m
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FlixBus8h 55m09:00 AMFrankfurt am MainCentral Station5:55 PMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/24/2025 9:00:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 12/24/2025 5:55:00 PM. 50 Economy ticket for $68 per person are available. Travel duration is 8h 55m
Fastest Flights Wednesday
Fastest Buses Wednesday
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Condor1h 0m02:15 PMFrankfurt am Main AirportFrankfurt am Main Airport3:15 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/25/2025 2:15:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/25/2025 3:15:00 PM. 50 Economy ticket for $162 per person are available. Travel duration is 1h 0m
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Condor1h 0m08:10 PMFrankfurt am Main AirportFrankfurt am Main Airport9:10 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/25/2025 8:10:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/25/2025 9:10:00 PM. 50 Economy ticket for $182 per person are available. Travel duration is 1h 0m
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Lufthansa1h 5m09:20 PMFrankfurt am Main AirportFrankfurt am Main Airport10:25 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/25/2025 9:20:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/25/2025 10:25:00 PM. 50 Economy ticket for $248 per person are available. Travel duration is 1h 5m
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Lufthansa1h 5m01:00 PMFrankfurt am Main AirportFrankfurt am Main Airport2:05 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/25/2025 1:00:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/25/2025 2:05:00 PM. 50 Economy ticket for $366 per person are available. Travel duration is 1h 5m
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FlixBus6h 56m011:59 PMFrankfurt am MainCentral Station6:55 AMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/25/2025 11:59:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 12/26/2025 6:55:00 AM. 50 Economy ticket for $66 per person are available. Travel duration is 6h 56m
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FlixBus7h 25m05:45 AMFrankfurt am MainCentral Station1:10 PMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/25/2025 5:45:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 12/25/2025 1:10:00 PM. 50 Economy ticket for $68 per person are available. Travel duration is 7h 25m
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FlixBus7h 55m011:15 AMFrankfurt am MainCentral Station7:10 PMPragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/25/2025 11:15:00 AM to Na Knížecí Station, Prague (Czech Republic) arriving at 12/25/2025 7:10:00 PM. 50 Economy ticket for $68 per person are available. Travel duration is 7h 55m
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FlixBus8h 10m01:00 PMFrankfurt am MainCentral Station9:10 PMPragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/25/2025 1:00:00 PM to Na Knížecí Station, Prague (Czech Republic) arriving at 12/25/2025 9:10:00 PM. 50 Economy ticket for $66 per person are available. Travel duration is 8h 10m
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FlixBus8h 30m01:00 PMFrankfurt am MainCentral Station9:30 PMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/25/2025 1:00:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 12/25/2025 9:30:00 PM. 50 Economy ticket for $66 per person are available. Travel duration is 8h 30m
Fastest Flights Thursday
Fastest Buses Thursday
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Condor1h 0m09:20 AMFrankfurt am Main AirportFrankfurt am Main Airport10:20 AMPrague AirportPrague Airport0EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/26/2025 9:20:00 AM to Prague Airport, Prague Airport (Czech Republic) arriving at 12/26/2025 10:20:00 AM. 50 Economy ticket for $217 per person are available. Travel duration is 1h 0m
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Lufthansa9h 5m012:50 PMFrankfurt am Main AirportFrankfurt am Main Airport9:55 PMPrague AirportPrague Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/26/2025 12:50:00 PM to Prague Airport, Prague Airport (Czech Republic) arriving at 12/26/2025 9:55:00 PM. 50 Economy ticket for $270 per person are available. Travel duration is 9h 5m
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Air Serbia9h 50m09:55 AMFrankfurt am Main AirportFrankfurt am Main Airport7:45 PMPrague AirportPrague Airport0EconomyA Flight from Air Serbia goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/26/2025 9:55:00 AM to Prague Airport, Prague Airport (Czech Republic) arriving at 12/26/2025 7:45:00 PM. 50 Economy ticket for $262 per person are available. Travel duration is 9h 50m
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EasyJet Airline11h 25m09:10 AMFrankfurt am Main AirportFrankfurt am Main Airport8:35 PMPrague AirportPrague Airport0EconomyA Flight from EasyJet Airline goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/26/2025 9:10:00 AM to Prague Airport, Prague Airport (Czech Republic) arriving at 12/26/2025 8:35:00 PM. 50 Economy ticket for $333 per person are available. Travel duration is 11h 25m
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Pegasus Group LTD17h 35m03:35 PMFrankfurt am Main AirportFrankfurt am Main Airport9:10 AMPrague AirportPrague Airport0EconomyA Flight from Pegasus Group LTD goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/26/2025 3:35:00 PM to Prague Airport, Prague Airport (Czech Republic) arriving at 12/27/2025 9:10:00 AM. 50 Economy ticket for $336 per person are available. Travel duration is 17h 35m
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FlixBus6h 56m011:59 PMFrankfurt am MainCentral Station6:55 AMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/26/2025 11:59:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 12/27/2025 6:55:00 AM. 50 Economy ticket for $66 per person are available. Travel duration is 6h 56m
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FlixBus7h 0m05:05 PMFrankfurt am MainCentral Station12:05 AMPragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/26/2025 5:05:00 PM to Na Knížecí Station, Prague (Czech Republic) arriving at 12/27/2025 12:05:00 AM. 50 Economy ticket for $64 per person are available. Travel duration is 7h 0m
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FlixBus7h 20m05:05 PMFrankfurt am MainCentral Station12:25 AMPragueWilsonova Bus Station0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/26/2025 5:05:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 12/27/2025 12:25:00 AM. 50 Economy ticket for $64 per person are available. Travel duration is 7h 20m
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FlixBus8h 15m01:50 AMFrankfurt am MainCentral Station10:05 AMPragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/26/2025 1:50:00 AM to Na Knížecí Station, Prague (Czech Republic) arriving at 12/26/2025 10:05:00 AM. 50 Economy ticket for $70 per person are available. Travel duration is 8h 15m
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FlixBus8h 56m011:59 PMFrankfurt am MainCentral Station8:55 AMPragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/26/2025 11:59:00 PM to Na Knížecí Station, Prague (Czech Republic) arriving at 12/27/2025 8:55:00 AM. 50 Economy ticket for $67 per person are available. Travel duration is 8h 56m
Fastest Flights Friday
Fastest Buses Friday
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Condor1h 0m09:20 AMFrankfurt am Main AirportFrankfurt am Main Airport10:20 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/27/2025 9:20:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/27/2025 10:20:00 AM. 50 Economy ticket for $208 per person are available. Travel duration is 1h 0m
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Condor1h 0m02:15 PMFrankfurt am Main AirportFrankfurt am Main Airport3:15 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/27/2025 2:15:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/27/2025 3:15:00 PM. 50 Economy ticket for $335 per person are available. Travel duration is 1h 0m
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Air Dolomiti1h 5m08:45 AMFrankfurt am Main AirportFrankfurt am Main Airport9:50 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Air Dolomiti goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/27/2025 8:45:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/27/2025 9:50:00 AM. 50 Economy ticket for $360 per person are available. Travel duration is 1h 5m
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Lufthansa1h 5m09:20 PMFrankfurt am Main AirportFrankfurt am Main Airport10:25 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/27/2025 9:20:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/27/2025 10:25:00 PM. 50 Economy ticket for $498 per person are available. Travel duration is 1h 5m
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Air Dolomiti1h 5m05:10 PMFrankfurt am Main AirportFrankfurt am Main Airport6:15 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Air Dolomiti goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/27/2025 5:10:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/27/2025 6:15:00 PM. 50 Economy ticket for $532 per person are available. Travel duration is 1h 5m
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FlixBus7h 0m05:05 PMFrankfurt am MainCentral Station12:05 AMPragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/27/2025 5:05:00 PM to Na Knížecí Station, Prague (Czech Republic) arriving at 12/28/2025 12:05:00 AM. 50 Economy ticket for $66 per person are available. Travel duration is 7h 0m
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FlixBus7h 20m05:05 PMFrankfurt am MainCentral Station12:25 AMPragueWilsonova Bus Station0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/27/2025 5:05:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 12/28/2025 12:25:00 AM. 50 Economy ticket for $66 per person are available. Travel duration is 7h 20m
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FlixBus8h 55m09:00 AMFrankfurt am MainCentral Station5:55 PMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/27/2025 9:00:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 12/27/2025 5:55:00 PM. 50 Economy ticket for $68 per person are available. Travel duration is 8h 55m
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FlixBus8h 56m011:59 PMFrankfurt am MainCentral Station8:55 AMPragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/27/2025 11:59:00 PM to Na Knížecí Station, Prague (Czech Republic) arriving at 12/28/2025 8:55:00 AM. 50 Economy ticket for $68 per person are available. Travel duration is 8h 56m
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FlixBus9h 45m08:15 PMFrankfurt am MainCentral Station6:00 AMPragueWilsonova Bus Station0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/27/2025 8:15:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 12/28/2025 6:00:00 AM. 50 Economy ticket for $68 per person are available. Travel duration is 9h 45m
Fastest Flights Saturday
Fastest Buses Saturday
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Condor1h 0m09:20 AMFrankfurt am Main AirportFrankfurt am Main Airport10:20 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/28/2025 9:20:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/28/2025 10:20:00 AM. 50 Economy ticket for $162 per person are available. Travel duration is 1h 0m
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Lufthansa1h 5m09:10 PMFrankfurt am Main AirportFrankfurt am Main Airport10:15 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/28/2025 9:10:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/28/2025 10:15:00 PM. 50 Economy ticket for $243 per person are available. Travel duration is 1h 5m
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Air Dolomiti1h 5m08:45 AMFrankfurt am Main AirportFrankfurt am Main Airport9:50 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Air Dolomiti goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/28/2025 8:45:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/28/2025 9:50:00 AM. 50 Economy ticket for $253 per person are available. Travel duration is 1h 5m
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Austrian Airlines3h 10m012:50 PMFrankfurt am Main AirportFrankfurt am Main Airport4:00 PMPrague AirportPrague Airport0EconomyA Flight from Austrian Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/28/2025 12:50:00 PM to Prague Airport, Prague Airport (Czech Republic) arriving at 12/28/2025 4:00:00 PM. 50 Economy ticket for $307 per person are available. Travel duration is 3h 10m
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EasyJet Airline8h 10m09:10 AMFrankfurt am Main AirportFrankfurt am Main Airport5:20 PMPrague AirportPrague Airport0EconomyA Flight from EasyJet Airline goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/28/2025 9:10:00 AM to Prague Airport, Prague Airport (Czech Republic) arriving at 12/28/2025 5:20:00 PM. 50 Economy ticket for $319 per person are available. Travel duration is 8h 10m
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RegioJet6h 45m010:00 PMFrankfurt am Main AirportFrankfurt am Main Airport4:45 AMPragueTrain station Wilsonova0EconomyA Bus from RegioJet goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/28/2025 10:00:00 PM to Train station Wilsonova, Prague (Czech Republic) arriving at 12/29/2025 4:45:00 AM. 50 Economy ticket for $53 per person are available. Travel duration is 6h 45m
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RegioJet6h 48m010:00 PMFrankfurt am Main AirportFrankfurt am Main Airport4:48 AMPragueÚAN Florenc0EconomyA Bus from RegioJet goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/28/2025 10:00:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 12/29/2025 4:48:00 AM. 50 Economy ticket for $53 per person are available. Travel duration is 6h 48m
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FlixBus7h 0m05:05 PMFrankfurt am MainCentral Station12:05 AMPragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/28/2025 5:05:00 PM to Na Knížecí Station, Prague (Czech Republic) arriving at 12/29/2025 12:05:00 AM. 50 Economy ticket for $66 per person are available. Travel duration is 7h 0m
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FlixBus7h 0m03:20 PMFrankfurt am MainCentral Station10:20 PMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/28/2025 3:20:00 PM to ÚAN Florenc, Prague (Czech Republic) arriving at 12/28/2025 10:20:00 PM. 50 Economy ticket for $68 per person are available. Travel duration is 7h 0m
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FlixBus7h 20m05:05 PMFrankfurt am MainCentral Station12:25 AMPragueWilsonova Bus Station0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/28/2025 5:05:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 12/29/2025 12:25:00 AM. 50 Economy ticket for $66 per person are available. Travel duration is 7h 20m
Fastest Flights Sunday
Fastest Buses Sunday
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Condor1h 0m02:15 PMFrankfurt am Main AirportFrankfurt am Main Airport3:15 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/29/2025 2:15:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/29/2025 3:15:00 PM. 50 Economy ticket for $180 per person are available. Travel duration is 1h 0m
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Lufthansa1h 5m09:20 PMFrankfurt am Main AirportFrankfurt am Main Airport10:25 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/29/2025 9:20:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/29/2025 10:25:00 PM. 50 Economy ticket for $216 per person are available. Travel duration is 1h 5m
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Air Dolomiti1h 5m05:10 PMFrankfurt am Main AirportFrankfurt am Main Airport6:15 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Air Dolomiti goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/29/2025 5:10:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/29/2025 6:15:00 PM. 50 Economy ticket for $257 per person are available. Travel duration is 1h 5m
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EasyJet Airline7h 20m09:10 AMFrankfurt am Main AirportFrankfurt am Main Airport4:30 PMPrague AirportPrague Airport0EconomyA Flight from EasyJet Airline goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/29/2025 9:10:00 AM to Prague Airport, Prague Airport (Czech Republic) arriving at 12/29/2025 4:30:00 PM. 50 Economy ticket for $297 per person are available. Travel duration is 7h 20m
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Air Serbia22h 40m09:55 AMFrankfurt am Main AirportFrankfurt am Main Airport8:35 AMPrague AirportPrague Airport0EconomyA Flight from Air Serbia goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/29/2025 9:55:00 AM to Prague Airport, Prague Airport (Czech Republic) arriving at 12/30/2025 8:35:00 AM. 50 Economy ticket for $262 per person are available. Travel duration is 22h 40m
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FlixBus7h 30m01:50 AMFrankfurt am MainCentral Station9:20 AMPragueÚAN Florenc0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/29/2025 1:50:00 AM to ÚAN Florenc, Prague (Czech Republic) arriving at 12/29/2025 9:20:00 AM. 50 Economy ticket for $64 per person are available. Travel duration is 7h 30m
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FlixBus8h 15m01:50 AMFrankfurt am MainCentral Station10:05 AMPragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/29/2025 1:50:00 AM to Na Knížecí Station, Prague (Czech Republic) arriving at 12/29/2025 10:05:00 AM. 50 Economy ticket for $64 per person are available. Travel duration is 8h 15m
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FlixBus8h 56m011:59 PMFrankfurt am MainCentral Station8:55 AMPragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/29/2025 11:59:00 PM to Na Knížecí Station, Prague (Czech Republic) arriving at 12/30/2025 8:55:00 AM. 50 Economy ticket for $57 per person are available. Travel duration is 8h 56m
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FlixBus9h 0m01:50 AMFrankfurt am MainCentral Station10:50 AMPragueWilsonova Bus Station0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/29/2025 1:50:00 AM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 12/29/2025 10:50:00 AM. 50 Economy ticket for $64 per person are available. Travel duration is 9h 0m
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FlixBus9h 50m06:10 AMFrankfurt am MainCentral Station4:00 PMPragueWilsonova Bus Station0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/29/2025 6:10:00 AM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 12/29/2025 4:00:00 PM. 50 Economy ticket for $57 per person are available. Travel duration is 9h 50m
Fastest Flights Monday
Fastest Buses Monday
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Condor1h 0m09:20 AMFrankfurt am Main AirportFrankfurt am Main Airport10:20 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/30/2025 9:20:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/30/2025 10:20:00 AM. 50 Economy ticket for $163 per person are available. Travel duration is 1h 0m
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Condor1h 0m02:15 PMFrankfurt am Main AirportFrankfurt am Main Airport3:15 PMPrague AirportPrague Airport - T1/20EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/30/2025 2:15:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/30/2025 3:15:00 PM. 50 Economy ticket for $211 per person are available. Travel duration is 1h 0m
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Air Dolomiti1h 5m08:30 AMFrankfurt am Main AirportFrankfurt am Main Airport9:35 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Air Dolomiti goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/30/2025 8:30:00 AM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/30/2025 9:35:00 AM. 50 Economy ticket for $236 per person are available. Travel duration is 1h 5m
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Ryanair13h 0m07:50 PMFrankfurt am Main AirportFrankfurt am Main Airport8:50 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Ryanair goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/30/2025 7:50:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/31/2025 8:50:00 AM. 50 Economy ticket for $173 per person are available. Travel duration is 13h 0m
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Ryanair17h 50m04:35 PMFrankfurt am Main AirportFrankfurt am Main Airport10:25 AMPrague AirportPrague Airport - T1/20EconomyA Flight from Ryanair goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 12/30/2025 4:35:00 PM to Prague Airport - T1/2, Prague Airport (Czech Republic) arriving at 12/31/2025 10:25:00 AM. 50 Economy ticket for $187 per person are available. Travel duration is 17h 50m
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FlixBus8h 15m01:50 AMFrankfurt am MainCentral Station10:05 AMPragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/30/2025 1:50:00 AM to Na Knížecí Station, Prague (Czech Republic) arriving at 12/30/2025 10:05:00 AM. 50 Economy ticket for $55 per person are available. Travel duration is 8h 15m
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FlixBus8h 56m011:59 PMFrankfurt am MainCentral Station8:55 AMPragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/30/2025 11:59:00 PM to Na Knížecí Station, Prague (Czech Republic) arriving at 12/31/2025 8:55:00 AM. 50 Economy ticket for $55 per person are available. Travel duration is 8h 56m
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FlixBus9h 0m01:50 AMFrankfurt am MainCentral Station10:50 AMPragueWilsonova Bus Station0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/30/2025 1:50:00 AM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 12/30/2025 10:50:00 AM. 50 Economy ticket for $55 per person are available. Travel duration is 9h 0m
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FlixBus9h 45m08:15 PMFrankfurt am MainCentral Station6:00 AMPragueWilsonova Bus Station0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/30/2025 8:15:00 PM to Wilsonova Bus Station, Prague (Czech Republic) arriving at 12/31/2025 6:00:00 AM. 50 Economy ticket for $55 per person are available. Travel duration is 9h 45m
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FlixBus9h 50m02:50 AMFrankfurt am MainCentral Station12:40 PMPragueNa Knížecí Station0EconomyA Bus from FlixBus goes from Central Station, Frankfurt am Main (Germany) at 12/30/2025 2:50:00 AM to Na Knížecí Station, Prague (Czech Republic) arriving at 12/30/2025 12:40:00 PM. 50 Economy ticket for $55 per person are available. Travel duration is 9h 50m
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Here you will find all operators and timetables for a
Bus from Frankfurt am Main to Prague
What are the most popular stations in Frankfurt am Main and Prague?
In Frankfurt am Main, you will usually depart from Central Station, Central Bus Station or West Train Station, while in Prague you will be arriving at Wilsonova Bus Station, ÚAN Florenc or Černý Most, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Prague from Frankfurt am Main? With 9 connections between 1 Bus and Flight operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Frankfurt am Main and Prague, you can pay as low as $53 with a Bus from RegioJet.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Condor: you will get to Prague in just 1h 0m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Frankfurt am Main and Prague are FlixBus, Condor and Lufthansa, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Frankfurt am Main and Prague is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Neu-Isenburg or to Horoměřice, and look at flights from Frankfurt am Main Airport, and landing at Prague Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Frankfurt am Main to Prague?
The most popular companies between Frankfurt am Main and Prague, are FlixBus, Condor and Lufthansa. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: FlixBus and RegioJet
Airlines: Condor, Lufthansa, Air Dolomiti and 5 more.
All you need to know when you travel from Frankfurt am Main to Prague
Check all information on comfort and services on all modes of transports from Frankfurt am Main to Prague. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Frankfurt am Main to Prague
How can I reach Prague from Frankfurt am Main?
Every day, there are on average 9 connections between Bus and Flight, with which you can get to Prague from Frankfurt am Main.
How far is Prague from Frankfurt am Main?
The distance between Frankfurt am Main and Prague is 255.2 miles.
What is the most ecofriendly mode of transport between Frankfurt am Main and Prague?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 11 kgs of CO2, a train 14 kgs, a car 70 kgs, and a flight 101 kgs.
What is the cheapest mode of transport from Frankfurt am Main to Prague?
You can get to Prague with just $53 by taking a Bus from RegioJet.
What is the fastest way to get from Frankfurt am Main to Prague?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Prague in just 1h 0m with a Flight from Condor.
More routes to Frankfurt am Main and to Prague
Looking for more options? Here you can see the most popular routes to Frankfurt am Main and to Prague. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Frankfurt am Main
- Amsterdam to Frankfurt am Main
- Basel to Frankfurt am Main
- Berlin to Frankfurt am Main
- Bern to Frankfurt am Main
- Birmingham to Frankfurt am Main
- Budapest to Frankfurt am Main
- Dusseldorf to Frankfurt am Main
- Frankfurt am Main Airport to Frankfurt am Main
- Frankfurt Hahn Airport to Frankfurt am Main
- Freiburg to Frankfurt am Main
- Graz to Frankfurt am Main
- Hamburg to Frankfurt am Main
- Hanover to Frankfurt am Main
- Innsbruck to Frankfurt am Main
- Linz to Frankfurt am Main
- London to Frankfurt am Main
- Munich to Frankfurt am Main
- Paris to Frankfurt am Main
- Priština to Frankfurt am Main
- Simmern (Hunsrück) to Frankfurt am Main
- Stuttgart to Frankfurt am Main
- Vienna to Frankfurt am Main
- Wroclaw to Frankfurt am Main
- Zurich to Frankfurt am Main
- Trips to Prague
- Amsterdam to Prague
- Berlin to Prague
- Brno to Prague
- Budapest to Prague
- Dresden to Prague
- Florence to Prague
- Karlovy Vary to Prague
- Katowice to Prague
- Krakow to Prague
- Linz to Prague
- London to Prague
- Lyon to Prague
- Michalovce to Prague
- Milan to Prague
- Minsk to Prague
- Munich to Prague
- Nuremberg to Prague
- Paris to Prague
- Pelhřimov to Prague
- Presov to Prague
- Třebíč to Prague
- Vienna to Prague
- Vilnius to Prague
- Zurich to Prague
