What is the best way to travel from Greenville, SC to Lexington, KY?
Looking for a trip? Compare all the available Flights and Buses for the journey to Lexington, KY from Greenville, SC. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 1 available companies to find your perfect trip!
What is the cheapest way to reach Lexington, KY from Greenville, SC?
You can get to Lexington, KY with just $67 by taking a Bus from Greyhound US, but you can find many more cheap offers: we have selected the best ones for next few days here for you.
-
Greyhound US11h 10m02:50 PMGreenville, SCWoodruff Rd2:00 AMLexington, KYGreyhound Bus Station0EconomyA Bus from Greyhound US goes from Woodruff Rd, Greenville, SC (USA) at 10/19/2026 2:50:00 PM to Greyhound Bus Station, Lexington, KY (USA) arriving at 10/20/2026 2:00:00 AM. 50 Economy ticket for $87 per person are available. Travel duration is 11h 10m
Cheapest Buses Monday
-
Greyhound US11h 10m02:50 PMGreenville, SCWoodruff Rd2:00 AMLexington, KYGreyhound Bus Station0EconomyA Bus from Greyhound US goes from Woodruff Rd, Greenville, SC (USA) at 10/23/2026 2:50:00 PM to Greyhound Bus Station, Lexington, KY (USA) arriving at 10/24/2026 2:00:00 AM. 50 Economy ticket for $67 per person are available. Travel duration is 11h 10m
Cheapest Buses Friday
What are the fastest trips from Greenville, SC to Lexington, KY?
You can get to Lexington, KY from Greenville, SC in just 11h 10m with a Bus from Greyhound US. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.
-
Greyhound US11h 10m02:50 PMGreenville, SCWoodruff Rd2:00 AMLexington, KYGreyhound Bus Station0EconomyA Bus from Greyhound US goes from Woodruff Rd, Greenville, SC (USA) at 10/19/2026 2:50:00 PM to Greyhound Bus Station, Lexington, KY (USA) arriving at 10/20/2026 2:00:00 AM. 50 Economy ticket for $87 per person are available. Travel duration is 11h 10m
Fastest Buses Monday
-
Greyhound US11h 10m02:50 PMGreenville, SCWoodruff Rd2:00 AMLexington, KYGreyhound Bus Station0EconomyA Bus from Greyhound US goes from Woodruff Rd, Greenville, SC (USA) at 10/23/2026 2:50:00 PM to Greyhound Bus Station, Lexington, KY (USA) arriving at 10/24/2026 2:00:00 AM. 50 Economy ticket for $67 per person are available. Travel duration is 11h 10m
Fastest Buses Friday
Here you will find all operators and timetables for a
Bus from Greenville, SC to Lexington, KY
What are the most popular stations in Greenville, SC and Lexington, KY?
In Greenville, SC, you will usually depart from Woodruff Rd, McDonald's or Greyhound Bus Station, while in Lexington, KY you will be arriving at Greyhound Bus Station, Alexandria Dr or University of Kentucky, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Lexington, KY from Greenville, SC? With 1 connections between 1 Flight and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Greenville, SC and Lexington, KY, you can pay as low as $67 with a Bus from Greyhound US.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Bus from Greyhound US: you will get to Lexington, KY in just 11h 10m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Greenville, SC and Lexington, KY are Greyhound US, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Greenville, SC and Lexington, KY is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Welcome, SC or to Lexington, KY, and look at flights from Greenville–Spartanburg Airport, and landing at Blue Grass Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Greenville, SC to Lexington, KY?
The most popular companies between Greenville, SC and Lexington, KY, are Greyhound US. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: Greyhound US
All you need to know when you travel from Greenville, SC to Lexington, KY
Check all information on comfort and services on all modes of transports from Greenville, SC to Lexington, KY. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Greenville, SC to Lexington, KY
How can I reach Lexington, KY from Greenville, SC?
Every day, there are on average 1 connections between Flight and Bus, with which you can get to Lexington, KY from Greenville, SC.
How far is Lexington, KY from Greenville, SC?
The distance between Greenville, SC and Lexington, KY is 249.6 miles.
What is the most ecofriendly mode of transport between Greenville, SC and Lexington, KY?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 11 kgs of CO2, a train 14 kgs, a car 68 kgs, and a flight 99 kgs.
What is the cheapest mode of transport from Greenville, SC to Lexington, KY?
You can get to Lexington, KY with just $67 by taking a Bus from Greyhound US.
What is the fastest way to get from Greenville, SC to Lexington, KY?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Lexington, KY in just 11h 10m with a Bus from Greyhound US.
More routes to Greenville, SC and to Lexington, KY
Looking for more options? Here you can see the most popular routes to Greenville, SC and to Lexington, KY. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Greenville, SC
- Nashville to Greenville, SC
- Orlando, FL to Greenville, SC
