What is the best way to travel from Mainz to Brussels?
Looking for a trip? Compare all the available Flights, Trains and Buses for the journey to Brussels from Mainz. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 2 available companies to find your perfect trip!
What is the cheapest way to reach Brussels from Mainz?
You can get to Brussels with just $25 by taking a Bus from FlixBus, but you can find many more cheap offers: we have selected the best ones for next few days here for you.
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FlixBus5h 45m012:20 PMMainzCentral Station6:05 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 2/1/2026 12:20:00 PM to North Station, Brussels (Belgium) arriving at 2/1/2026 6:05:00 PM. 50 Economy ticket for $40 per person are available. Travel duration is 5h 45m
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FlixBus8h 5m07:30 PMFrankfurt am Main AirportFrankfurt am Main Airport3:35 AMBrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 2/1/2026 7:30:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 2/2/2026 3:35:00 AM. 50 Economy ticket for $45 per person are available. Travel duration is 8h 5m
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FlixBus8h 25m09:50 AMFrankfurt am Main AirportFrankfurt am Main Airport6:15 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 2/1/2026 9:50:00 AM to North Station, Brussels (Belgium) arriving at 2/1/2026 6:15:00 PM. 50 Economy ticket for $46 per person are available. Travel duration is 8h 25m
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FlixBus9h 15m011:00 AMFrankfurt am Main AirportFrankfurt am Main Airport8:15 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 2/1/2026 11:00:00 AM to North Station, Brussels (Belgium) arriving at 2/1/2026 8:15:00 PM. 50 Economy ticket for $46 per person are available. Travel duration is 9h 15m
Cheapest Buses Sunday
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Pegasus Group LTD15h 25m06:35 PMFrankfurt am Main AirportFrankfurt am Main Airport10:00 AMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Pegasus Group LTD goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 2/2/2026 6:35:00 PM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 2/3/2026 10:00:00 AM. 50 Economy ticket for $171 per person are available. Travel duration is 15h 25m
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Pegasus Group LTD19h 20m06:35 PMFrankfurt am Main AirportFrankfurt am Main Airport1:55 PMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Pegasus Group LTD goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 2/2/2026 6:35:00 PM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 2/3/2026 1:55:00 PM. 50 Economy ticket for $172 per person are available. Travel duration is 19h 20m
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Pegasus Group LTD18h 10m06:35 PMFrankfurt am Main AirportFrankfurt am Main Airport12:45 PMBrussels AirportBrussels Airport0EconomyA Flight from Pegasus Group LTD goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 2/2/2026 6:35:00 PM to Brussels Airport, Brussels Airport (Belgium) arriving at 2/3/2026 12:45:00 PM. 50 Economy ticket for $173 per person are available. Travel duration is 18h 10m
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Lufthansa3h 5m010:05 AMFrankfurt am Main AirportFrankfurt am Main Airport1:10 PMBrussels AirportBrussels Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 2/2/2026 10:05:00 AM to Brussels Airport, Brussels Airport (Belgium) arriving at 2/2/2026 1:10:00 PM. 50 Economy ticket for $228 per person are available. Travel duration is 3h 5m
Cheapest Flights Monday
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FlixBus6h 55m012:25 AMFrankfurt am Main AirportFrankfurt am Main Airport7:20 AMBrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 2/3/2026 12:25:00 AM to Midi Bus Station, Brussels (Belgium) arriving at 2/3/2026 7:20:00 AM. 50 Economy ticket for $25 per person are available. Travel duration is 6h 55m
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FlixBus6h 50m02:30 AMFrankfurt am Main AirportFrankfurt am Main Airport9:20 AMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 2/3/2026 2:30:00 AM to North Station, Brussels (Belgium) arriving at 2/3/2026 9:20:00 AM. 50 Economy ticket for $27 per person are available. Travel duration is 6h 50m
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FlixBus8h 25m07:10 PMFrankfurt am Main AirportFrankfurt am Main Airport3:35 AMBrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 2/3/2026 7:10:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 2/4/2026 3:35:00 AM. 50 Economy ticket for $34 per person are available. Travel duration is 8h 25m
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FlixBus9h 20m03:05 PMFrankfurt am Main AirportFrankfurt am Main Airport12:25 AMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 2/3/2026 3:05:00 PM to North Station, Brussels (Belgium) arriving at 2/4/2026 12:25:00 AM. 50 Economy ticket for $34 per person are available. Travel duration is 9h 20m
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EasyJet Airline23h 30m09:10 AMFrankfurt am Main AirportFrankfurt am Main Airport8:40 AMBrussels AirportBrussels Airport0EconomyA Flight from EasyJet Airline goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 2/3/2026 9:10:00 AM to Brussels Airport, Brussels Airport (Belgium) arriving at 2/4/2026 8:40:00 AM. 50 Economy ticket for $132 per person are available. Travel duration is 23h 30m
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Pegasus Group LTD18h 50m03:35 PMFrankfurt am Main AirportFrankfurt am Main Airport10:25 AMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Pegasus Group LTD goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 2/3/2026 3:35:00 PM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 2/4/2026 10:25:00 AM. 50 Economy ticket for $147 per person are available. Travel duration is 18h 50m
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Pegasus Group LTD22h 10m03:35 PMFrankfurt am Main AirportFrankfurt am Main Airport1:45 PMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Pegasus Group LTD goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 2/3/2026 3:35:00 PM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 2/4/2026 1:45:00 PM. 50 Economy ticket for $147 per person are available. Travel duration is 22h 10m
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AJet20h 30m01:55 PMFrankfurt am Main AirportFrankfurt am Main Airport10:25 AMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from AJet goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 2/3/2026 1:55:00 PM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 2/4/2026 10:25:00 AM. 50 Economy ticket for $148 per person are available. Travel duration is 20h 30m
Cheapest Buses Tuesday
Cheapest Flights Tuesday
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EasyJet Airline11h 25m09:10 AMFrankfurt am Main AirportFrankfurt am Main Airport8:35 PMBrussels AirportBrussels Airport0EconomyA Flight from EasyJet Airline goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 2/4/2026 9:10:00 AM to Brussels Airport, Brussels Airport (Belgium) arriving at 2/4/2026 8:35:00 PM. 50 Economy ticket for $117 per person are available. Travel duration is 11h 25m
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TAROM21h 35m011:15 AMFrankfurt am Main AirportFrankfurt am Main Airport8:50 AMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from TAROM goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 2/4/2026 11:15:00 AM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 2/5/2026 8:50:00 AM. 50 Economy ticket for $143 per person are available. Travel duration is 21h 35m
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Lufthansa12h 0m08:40 PMFrankfurt am Main AirportFrankfurt am Main Airport8:40 AMBrussels AirportBrussels Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 2/4/2026 8:40:00 PM to Brussels Airport, Brussels Airport (Belgium) arriving at 2/5/2026 8:40:00 AM. 50 Economy ticket for $155 per person are available. Travel duration is 12h 0m
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Aer Lingus7h 30m010:45 AMFrankfurt am Main AirportFrankfurt am Main Airport6:15 PMBrussels AirportBrussels Airport0EconomyA Flight from Aer Lingus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 2/4/2026 10:45:00 AM to Brussels Airport, Brussels Airport (Belgium) arriving at 2/4/2026 6:15:00 PM. 50 Economy ticket for $164 per person are available. Travel duration is 7h 30m
Cheapest Flights Wednesday
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EasyJet Airline23h 20m09:20 AMFrankfurt am Main AirportFrankfurt am Main Airport8:40 AMBrussels AirportBrussels Airport0EconomyA Flight from EasyJet Airline goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 2/5/2026 9:20:00 AM to Brussels Airport, Brussels Airport (Belgium) arriving at 2/6/2026 8:40:00 AM. 50 Economy ticket for $136 per person are available. Travel duration is 23h 20m
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AJet20h 25m01:45 PMFrankfurt am Main AirportFrankfurt am Main Airport10:10 AMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from AJet goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 2/5/2026 1:45:00 PM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 2/6/2026 10:10:00 AM. 50 Economy ticket for $146 per person are available. Travel duration is 20h 25m
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Pegasus Group LTD18h 35m03:35 PMFrankfurt am Main AirportFrankfurt am Main Airport10:10 AMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Pegasus Group LTD goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 2/5/2026 3:35:00 PM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 2/6/2026 10:10:00 AM. 50 Economy ticket for $147 per person are available. Travel duration is 18h 35m
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AJet23h 0m01:45 PMFrankfurt am Main AirportFrankfurt am Main Airport12:45 PMBrussels AirportBrussels Airport0EconomyA Flight from AJet goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 2/5/2026 1:45:00 PM to Brussels Airport, Brussels Airport (Belgium) arriving at 2/6/2026 12:45:00 PM. 50 Economy ticket for $147 per person are available. Travel duration is 23h 0m
Cheapest Flights Thursday
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EasyJet Airline23h 25m08:10 PMFrankfurt am Main AirportFrankfurt am Main Airport7:35 PMBrussels AirportBrussels Airport0EconomyA Flight from EasyJet Airline goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 2/6/2026 8:10:00 PM to Brussels Airport, Brussels Airport (Belgium) arriving at 2/7/2026 7:35:00 PM. 50 Economy ticket for $136 per person are available. Travel duration is 23h 25m
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Aer Lingus13h 35m08:00 PMFrankfurt am Main AirportFrankfurt am Main Airport9:35 AMBrussels AirportBrussels Airport0EconomyA Flight from Aer Lingus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 2/6/2026 8:00:00 PM to Brussels Airport, Brussels Airport (Belgium) arriving at 2/7/2026 9:35:00 AM. 50 Economy ticket for $136 per person are available. Travel duration is 13h 35m
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Pegasus Group LTD15h 45m06:35 PMFrankfurt am Main AirportFrankfurt am Main Airport10:20 AMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Pegasus Group LTD goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 2/6/2026 6:35:00 PM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 2/7/2026 10:20:00 AM. 50 Economy ticket for $164 per person are available. Travel duration is 15h 45m
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Lufthansa22h 50m08:45 PMFrankfurt am Main AirportFrankfurt am Main Airport7:35 PMBrussels AirportBrussels Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 2/6/2026 8:45:00 PM to Brussels Airport, Brussels Airport (Belgium) arriving at 2/7/2026 7:35:00 PM. 50 Economy ticket for $168 per person are available. Travel duration is 22h 50m
Cheapest Flights Friday
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FlixBus5h 45m012:20 PMMainzCentral Station6:05 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 2/7/2026 12:20:00 PM to North Station, Brussels (Belgium) arriving at 2/7/2026 6:05:00 PM. 50 Economy ticket for $26 per person are available. Travel duration is 5h 45m
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FlixBus7h 30m01:00 AMMainzCentral Station8:30 AMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 2/7/2026 1:00:00 AM to North Station, Brussels (Belgium) arriving at 2/7/2026 8:30:00 AM. 50 Economy ticket for $33 per person are available. Travel duration is 7h 30m
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Deutsche Bahn2h 48m06:48 AMFrankfurt am Main AirportFrankfurt am Main Airport Train Station9:36 AMBrusselsCentral Station0EconomyA Train from Deutsche Bahn goes from Frankfurt am Main Airport Train Station, Frankfurt am Main Airport (Germany) at 2/7/2026 6:48:00 AM to Central Station, Brussels (Belgium) arriving at 2/7/2026 9:36:00 AM. 50 Economy ticket for $64 per person are available. Travel duration is 2h 48m
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Deutsche Bahn5h 48m05:59 PMFrankfurt am Main AirportFrankfurt am Main Airport Train Station11:47 PMBrusselsCentral Station0EconomyA Train from Deutsche Bahn goes from Frankfurt am Main Airport Train Station, Frankfurt am Main Airport (Germany) at 2/7/2026 5:59:00 PM to Central Station, Brussels (Belgium) arriving at 2/7/2026 11:47:00 PM. 50 Economy ticket for $64 per person are available. Travel duration is 5h 48m
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Deutsche Bahn3h 31m08:16 PMFrankfurt am Main AirportFrankfurt am Main Airport Train Station11:47 PMBrusselsCentral Station0EconomyA Train from Deutsche Bahn goes from Frankfurt am Main Airport Train Station, Frankfurt am Main Airport (Germany) at 2/7/2026 8:16:00 PM to Central Station, Brussels (Belgium) arriving at 2/7/2026 11:47:00 PM. 50 Economy ticket for $64 per person are available. Travel duration is 3h 31m
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Deutsche Bahn3h 25m08:22 PMFrankfurt am Main AirportFrankfurt am Main Airport Train Station11:47 PMBrusselsCentral Station0EconomyA Train from Deutsche Bahn goes from Frankfurt am Main Airport Train Station, Frankfurt am Main Airport (Germany) at 2/7/2026 8:22:00 PM to Central Station, Brussels (Belgium) arriving at 2/7/2026 11:47:00 PM. 50 Economy ticket for $71 per person are available. Travel duration is 3h 25m
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EasyJet Airline23h 25m09:15 AMFrankfurt am Main AirportFrankfurt am Main Airport8:40 AMBrussels AirportBrussels Airport0EconomyA Flight from EasyJet Airline goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 2/7/2026 9:15:00 AM to Brussels Airport, Brussels Airport (Belgium) arriving at 2/8/2026 8:40:00 AM. 50 Economy ticket for $146 per person are available. Travel duration is 23h 25m
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Pegasus Group LTD15h 50m06:35 PMFrankfurt am Main AirportFrankfurt am Main Airport10:25 AMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Pegasus Group LTD goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 2/7/2026 6:35:00 PM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 2/8/2026 10:25:00 AM. 50 Economy ticket for $222 per person are available. Travel duration is 15h 50m
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Lufthansa18h 15m03:20 PMFrankfurt am Main AirportFrankfurt am Main Airport9:35 AMBrussels AirportBrussels Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 2/7/2026 3:20:00 PM to Brussels Airport, Brussels Airport (Belgium) arriving at 2/8/2026 9:35:00 AM. 50 Economy ticket for $235 per person are available. Travel duration is 18h 15m
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Condor12h 30m08:10 PMFrankfurt am Main AirportFrankfurt am Main Airport8:40 AMBrussels AirportBrussels Airport0EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 2/7/2026 8:10:00 PM to Brussels Airport, Brussels Airport (Belgium) arriving at 2/8/2026 8:40:00 AM. 50 Economy ticket for $243 per person are available. Travel duration is 12h 30m
Cheapest Buses Saturday
Cheapest Trains Saturday
Cheapest Flights Saturday
What are the fastest trips from Mainz to Brussels?
You can get to Brussels from Mainz in just 1h 10m with a Flight from Brussels Airlines. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.
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FlixBus5h 45m012:20 PMMainzCentral Station6:05 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 2/1/2026 12:20:00 PM to North Station, Brussels (Belgium) arriving at 2/1/2026 6:05:00 PM. 50 Economy ticket for $40 per person are available. Travel duration is 5h 45m
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FlixBus8h 5m07:30 PMFrankfurt am Main AirportFrankfurt am Main Airport3:35 AMBrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 2/1/2026 7:30:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 2/2/2026 3:35:00 AM. 50 Economy ticket for $45 per person are available. Travel duration is 8h 5m
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FlixBus8h 25m09:50 AMFrankfurt am Main AirportFrankfurt am Main Airport6:15 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 2/1/2026 9:50:00 AM to North Station, Brussels (Belgium) arriving at 2/1/2026 6:15:00 PM. 50 Economy ticket for $46 per person are available. Travel duration is 8h 25m
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FlixBus9h 5m01:25 PMFrankfurt am Main AirportFrankfurt am Main Airport10:30 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 2/1/2026 1:25:00 PM to North Station, Brussels (Belgium) arriving at 2/1/2026 10:30:00 PM. 50 Economy ticket for $46 per person are available. Travel duration is 9h 5m
Fastest Buses Sunday
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Lufthansa3h 5m010:05 AMFrankfurt am Main AirportFrankfurt am Main Airport1:10 PMBrussels AirportBrussels Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 2/2/2026 10:05:00 AM to Brussels Airport, Brussels Airport (Belgium) arriving at 2/2/2026 1:10:00 PM. 50 Economy ticket for $228 per person are available. Travel duration is 3h 5m
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Lufthansa5h 55m010:00 AMFrankfurt am Main AirportFrankfurt am Main Airport3:55 PMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 2/2/2026 10:00:00 AM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 2/2/2026 3:55:00 PM. 50 Economy ticket for $428 per person are available. Travel duration is 5h 55m
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Lufthansa9h 0m010:20 AMFrankfurt am Main AirportFrankfurt am Main Airport7:20 PMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 2/2/2026 10:20:00 AM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 2/2/2026 7:20:00 PM. 50 Economy ticket for $358 per person are available. Travel duration is 9h 0m
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Lufthansa11h 20m09:00 PMFrankfurt am Main AirportFrankfurt am Main Airport8:20 AMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 2/2/2026 9:00:00 PM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 2/3/2026 8:20:00 AM. 50 Economy ticket for $417 per person are available. Travel duration is 11h 20m
Fastest Flights Monday
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FlixBus6h 50m02:30 AMFrankfurt am Main AirportFrankfurt am Main Airport9:20 AMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 2/3/2026 2:30:00 AM to North Station, Brussels (Belgium) arriving at 2/3/2026 9:20:00 AM. 50 Economy ticket for $27 per person are available. Travel duration is 6h 50m
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FlixBus6h 55m012:25 AMFrankfurt am Main AirportFrankfurt am Main Airport7:20 AMBrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 2/3/2026 12:25:00 AM to Midi Bus Station, Brussels (Belgium) arriving at 2/3/2026 7:20:00 AM. 50 Economy ticket for $25 per person are available. Travel duration is 6h 55m
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FlixBus8h 25m07:10 PMFrankfurt am Main AirportFrankfurt am Main Airport3:35 AMBrusselsMidi Bus Station0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 2/3/2026 7:10:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 2/4/2026 3:35:00 AM. 50 Economy ticket for $34 per person are available. Travel duration is 8h 25m
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FlixBus9h 20m03:05 PMFrankfurt am Main AirportFrankfurt am Main Airport12:25 AMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 2/3/2026 3:05:00 PM to North Station, Brussels (Belgium) arriving at 2/4/2026 12:25:00 AM. 50 Economy ticket for $34 per person are available. Travel duration is 9h 20m
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Iberia14h 15m07:35 PMFrankfurt am Main AirportFrankfurt am Main Airport9:50 AMBrussels AirportBrussels Airport0EconomyA Flight from Iberia goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 2/3/2026 7:35:00 PM to Brussels Airport, Brussels Airport (Belgium) arriving at 2/4/2026 9:50:00 AM. 50 Economy ticket for $211 per person are available. Travel duration is 14h 15m
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Air Europa14h 45m07:05 PMFrankfurt am Main AirportFrankfurt am Main Airport9:50 AMBrussels AirportBrussels Airport0EconomyA Flight from Air Europa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 2/3/2026 7:05:00 PM to Brussels Airport, Brussels Airport (Belgium) arriving at 2/4/2026 9:50:00 AM. 50 Economy ticket for $226 per person are available. Travel duration is 14h 45m
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Lufthansa15h 45m04:55 PMFrankfurt am Main AirportFrankfurt am Main Airport8:40 AMBrussels AirportBrussels Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 2/3/2026 4:55:00 PM to Brussels Airport, Brussels Airport (Belgium) arriving at 2/4/2026 8:40:00 AM. 50 Economy ticket for $220 per person are available. Travel duration is 15h 45m
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Lufthansa17h 45m08:35 PMFrankfurt am Main AirportFrankfurt am Main Airport2:20 PMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 2/3/2026 8:35:00 PM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 2/4/2026 2:20:00 PM. 50 Economy ticket for $409 per person are available. Travel duration is 17h 45m
Fastest Buses Tuesday
Fastest Flights Tuesday
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Brussels Airlines1h 10m09:00 AMFrankfurt am Main AirportFrankfurt am Main Airport10:10 AMBrussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 2/4/2026 9:00:00 AM to Brussels Airport, Brussels Airport (Belgium) arriving at 2/4/2026 10:10:00 AM. 50 Economy ticket for $199 per person are available. Travel duration is 1h 10m
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TAROM7h 5m011:15 AMFrankfurt am Main AirportFrankfurt am Main Airport6:20 PMBrussels AirportBrussels Airport0EconomyA Flight from TAROM goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 2/4/2026 11:15:00 AM to Brussels Airport, Brussels Airport (Belgium) arriving at 2/4/2026 6:20:00 PM. 50 Economy ticket for $190 per person are available. Travel duration is 7h 5m
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Aer Lingus7h 30m010:45 AMFrankfurt am Main AirportFrankfurt am Main Airport6:15 PMBrussels AirportBrussels Airport0EconomyA Flight from Aer Lingus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 2/4/2026 10:45:00 AM to Brussels Airport, Brussels Airport (Belgium) arriving at 2/4/2026 6:15:00 PM. 50 Economy ticket for $164 per person are available. Travel duration is 7h 30m
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Lufthansa11h 20m09:00 PMFrankfurt am Main AirportFrankfurt am Main Airport8:20 AMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 2/4/2026 9:00:00 PM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 2/5/2026 8:20:00 AM. 50 Economy ticket for $200 per person are available. Travel duration is 11h 20m
Fastest Flights Wednesday
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Austrian Airlines4h 55m06:50 AMFrankfurt am Main AirportFrankfurt am Main Airport11:45 AMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Austrian Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 2/5/2026 6:50:00 AM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 2/5/2026 11:45:00 AM. 50 Economy ticket for $213 per person are available. Travel duration is 4h 55m
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TAROM6h 15m011:15 AMFrankfurt am Main AirportFrankfurt am Main Airport5:30 PMBrussels AirportBrussels Airport0EconomyA Flight from TAROM goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 2/5/2026 11:15:00 AM to Brussels Airport, Brussels Airport (Belgium) arriving at 2/5/2026 5:30:00 PM. 50 Economy ticket for $209 per person are available. Travel duration is 6h 15m
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Croatia Airlines7h 5m09:30 AMFrankfurt am Main AirportFrankfurt am Main Airport4:35 PMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Croatia Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 2/5/2026 9:30:00 AM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 2/5/2026 4:35:00 PM. 50 Economy ticket for $161 per person are available. Travel duration is 7h 5m
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Lufthansa7h 35m012:50 PMFrankfurt am Main AirportFrankfurt am Main Airport8:25 PMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 2/5/2026 12:50:00 PM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 2/5/2026 8:25:00 PM. 50 Economy ticket for $154 per person are available. Travel duration is 7h 35m
Fastest Flights Thursday
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Brussels Airlines1h 10m09:00 AMFrankfurt am Main AirportFrankfurt am Main Airport10:10 AMBrussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 2/6/2026 9:00:00 AM to Brussels Airport, Brussels Airport (Belgium) arriving at 2/6/2026 10:10:00 AM. 50 Economy ticket for $199 per person are available. Travel duration is 1h 10m
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Swiss International Air Lines3h 45m09:50 AMFrankfurt am Main AirportFrankfurt am Main Airport1:35 PMBrussels AirportBrussels Airport0EconomyA Flight from Swiss International Air Lines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 2/6/2026 9:50:00 AM to Brussels Airport, Brussels Airport (Belgium) arriving at 2/6/2026 1:35:00 PM. 50 Economy ticket for $236 per person are available. Travel duration is 3h 45m
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Lufthansa7h 25m01:00 PMFrankfurt am Main AirportFrankfurt am Main Airport8:25 PMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 2/6/2026 1:00:00 PM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 2/6/2026 8:25:00 PM. 50 Economy ticket for $219 per person are available. Travel duration is 7h 25m
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Lufthansa7h 45m02:35 PMFrankfurt am Main AirportFrankfurt am Main Airport10:20 PMAntwerp AirportAntwerp Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 2/6/2026 2:35:00 PM to Antwerp Airport, Antwerp Airport (Belgium) arriving at 2/6/2026 10:20:00 PM. 50 Economy ticket for $442 per person are available. Travel duration is 7h 45m
Fastest Flights Friday
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Deutsche Bahn2h 48m06:48 AMFrankfurt am Main AirportFrankfurt am Main Airport Train Station9:36 AMBrusselsCentral Station0EconomyA Train from Deutsche Bahn goes from Frankfurt am Main Airport Train Station, Frankfurt am Main Airport (Germany) at 2/7/2026 6:48:00 AM to Central Station, Brussels (Belgium) arriving at 2/7/2026 9:36:00 AM. 50 Economy ticket for $64 per person are available. Travel duration is 2h 48m
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Deutsche Bahn3h 25m08:22 PMFrankfurt am Main AirportFrankfurt am Main Airport Train Station11:47 PMBrusselsCentral Station0EconomyA Train from Deutsche Bahn goes from Frankfurt am Main Airport Train Station, Frankfurt am Main Airport (Germany) at 2/7/2026 8:22:00 PM to Central Station, Brussels (Belgium) arriving at 2/7/2026 11:47:00 PM. 50 Economy ticket for $71 per person are available. Travel duration is 3h 25m
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Deutsche Bahn3h 31m08:16 PMFrankfurt am Main AirportFrankfurt am Main Airport Train Station11:47 PMBrusselsCentral Station0EconomyA Train from Deutsche Bahn goes from Frankfurt am Main Airport Train Station, Frankfurt am Main Airport (Germany) at 2/7/2026 8:16:00 PM to Central Station, Brussels (Belgium) arriving at 2/7/2026 11:47:00 PM. 50 Economy ticket for $64 per person are available. Travel duration is 3h 31m
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Deutsche Bahn5h 37m07:59 AMFrankfurt am Main AirportFrankfurt am Main Airport Train Station1:36 PMBrusselsCentral Station0EconomyA Train from Deutsche Bahn goes from Frankfurt am Main Airport Train Station, Frankfurt am Main Airport (Germany) at 2/7/2026 7:59:00 AM to Central Station, Brussels (Belgium) arriving at 2/7/2026 1:36:00 PM. 50 Economy ticket for $73 per person are available. Travel duration is 5h 37m
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FlixBus5h 45m012:20 PMMainzCentral Station6:05 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 2/7/2026 12:20:00 PM to North Station, Brussels (Belgium) arriving at 2/7/2026 6:05:00 PM. 50 Economy ticket for $26 per person are available. Travel duration is 5h 45m
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FlixBus7h 30m01:00 AMMainzCentral Station8:30 AMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 2/7/2026 1:00:00 AM to North Station, Brussels (Belgium) arriving at 2/7/2026 8:30:00 AM. 50 Economy ticket for $33 per person are available. Travel duration is 7h 30m
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Lufthansa8h 10m07:45 AMFrankfurt am Main AirportFrankfurt am Main Airport3:55 PMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 2/7/2026 7:45:00 AM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 2/7/2026 3:55:00 PM. 50 Economy ticket for $321 per person are available. Travel duration is 8h 10m
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Lufthansa11h 20m09:00 PMFrankfurt am Main AirportFrankfurt am Main Airport8:20 AMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 2/7/2026 9:00:00 PM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 2/8/2026 8:20:00 AM. 50 Economy ticket for $296 per person are available. Travel duration is 11h 20m
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Condor12h 30m08:10 PMFrankfurt am Main AirportFrankfurt am Main Airport8:40 AMBrussels AirportBrussels Airport0EconomyA Flight from Condor goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 2/7/2026 8:10:00 PM to Brussels Airport, Brussels Airport (Belgium) arriving at 2/8/2026 8:40:00 AM. 50 Economy ticket for $243 per person are available. Travel duration is 12h 30m
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Pegasus Group LTD15h 50m06:35 PMFrankfurt am Main AirportFrankfurt am Main Airport10:25 AMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Pegasus Group LTD goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 2/7/2026 6:35:00 PM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 2/8/2026 10:25:00 AM. 50 Economy ticket for $222 per person are available. Travel duration is 15h 50m
Fastest Trains Saturday
Fastest Buses Saturday
Fastest Flights Saturday
Here you will find all operators and timetables for a
Bus from Mainz to Brussels
What are the most popular stations in Mainz and Brussels?
In Mainz, you will usually depart from Central Station, Central Bus Station or Laubenheim Train Station, while in Brussels you will be arriving at Midi Bus Station, North Station or Gare Centrale, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Brussels from Mainz? With 12 connections between 2 Flight, Train and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Mainz and Brussels, you can pay as low as $25 with a Bus from FlixBus.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Brussels Airlines: you will get to Brussels in just 1h 10m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Mainz and Brussels are Lufthansa, FlixBus and Pegasus Group LTD, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Mainz and Brussels is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Budenheim or to Saint-Gilles, and look at flights from Frankfurt am Main Airport, and landing at Brussels South Charleroi Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Mainz to Brussels?
The most popular companies between Mainz and Brussels, are Lufthansa, FlixBus and Pegasus Group LTD. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: FlixBus
Train companies: Deutsche Bahn
Airlines: Lufthansa, Pegasus Group LTD, EasyJet Airline and 13 more.
All you need to know when you travel from Mainz to Brussels
Check all information on comfort and services on all modes of transports from Mainz to Brussels. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Mainz to Brussels
How can I reach Brussels from Mainz?
Every day, there are on average 12 connections between Flight, Train and Bus, with which you can get to Brussels from Mainz.
How far is Brussels from Mainz?
The distance between Mainz and Brussels is 181.5 miles.
What is the most ecofriendly mode of transport between Mainz and Brussels?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 8 kgs of CO2, a train 10 kgs, a car 50 kgs, and a flight 72 kgs.
What is the cheapest mode of transport from Mainz to Brussels?
You can get to Brussels with just $25 by taking a Bus from FlixBus.
What is the fastest way to get from Mainz to Brussels?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Brussels in just 1h 10m with a Flight from Brussels Airlines.
More routes to Mainz and to Brussels
Looking for more options? Here you can see the most popular routes to Mainz and to Brussels. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Mainz
- Berlin to Mainz
- Brussels to Mainz
- Dresden to Mainz
- Frankfurt am Main Airport to Mainz
- Frankfurt Hahn Airport to Mainz
- Freiburg to Mainz
- Heidelberg to Mainz
- Kaiserslautern to Mainz
- Katowice to Mainz
- Koblenz to Mainz
- Munich to Mainz
- Saarbruecken to Mainz
- Simmern (Hunsrück) to Mainz
- Trips to Brussels
- Aachen to Brussels
- Amsterdam to Brussels
- Antwerp to Brussels
- Barcelona to Brussels
- Birmingham to Brussels
- Bordeaux to Brussels
- Bristol to Brussels
- Brussels South Charleroi Airport to Brussels
- Dusseldorf to Brussels
- Edinburgh to Brussels
- Le Mans to Brussels
- Lille to Brussels
- Lisbon to Brussels
- London to Brussels
- Lyon to Brussels
- Madrid to Brussels
- Newcastle upon Tyne to Brussels
- Nottingham to Brussels
- Paris to Brussels
- Porto to Brussels
- The Hague to Brussels
- Toulouse to Brussels
- Valencia to Brussels
- Zurich to Brussels
