What is the best way to travel from Mainz to Brussels?
Looking for a trip? Compare all the available Flights, Trains and Buses for the journey to Brussels from Mainz. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 2 available companies to find your perfect trip!
What is the cheapest way to reach Brussels from Mainz?
You can get to Brussels with just $25 by taking a Bus from FlixBus, but you can find many more cheap offers: we have selected the best ones for next few days here for you.
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FlixBus5h 50m012:05 PMMainzCentral Station5:55 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 11/6/2026 12:05:00 PM to North Station, Brussels (Belgium) arriving at 11/6/2026 5:55:00 PM. 50 Economy ticket for $25 per person are available. Travel duration is 5h 50m
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FlixBus8h 25m08:15 AMMainzCentral Station4:40 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 11/6/2026 8:15:00 AM to North Station, Brussels (Belgium) arriving at 11/6/2026 4:40:00 PM. 50 Economy ticket for $32 per person are available. Travel duration is 8h 25m
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FlixBus9h 15m011:00 AMFrankfurt am Main AirportFrankfurt am Main Airport8:15 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 11/6/2026 11:00:00 AM to North Station, Brussels (Belgium) arriving at 11/6/2026 8:15:00 PM. 50 Economy ticket for $34 per person are available. Travel duration is 9h 15m
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BlaBlaCar Bus13h 48m012:25 PMFrankfurt am Main AirportFrankfurt am Main Airport2:13 AMBrusselsMidi Bus Station0EconomyA Bus from BlaBlaCar Bus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 11/6/2026 12:25:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 11/7/2026 2:13:00 AM. 50 Economy ticket for $118 per person are available. Travel duration is 13h 48m
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Brussels Airlines1h 5m011:30 AMFrankfurt am Main AirportFrankfurt am Main Airport12:35 PMBrussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 11/6/2026 11:30:00 AM to Brussels Airport, Brussels Airport (Belgium) arriving at 11/6/2026 12:35:00 PM. 50 Economy ticket for $209 per person are available. Travel duration is 1h 5m
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Brussels Airlines1h 5m012:30 PMFrankfurt am Main AirportFrankfurt am Main Airport1:35 PMBrussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 11/6/2026 12:30:00 PM to Brussels Airport, Brussels Airport (Belgium) arriving at 11/6/2026 1:35:00 PM. 50 Economy ticket for $209 per person are available. Travel duration is 1h 5m
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Brussels Airlines1h 5m04:25 PMFrankfurt am Main AirportFrankfurt am Main Airport5:30 PMBrussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 11/6/2026 4:25:00 PM to Brussels Airport, Brussels Airport (Belgium) arriving at 11/6/2026 5:30:00 PM. 50 Economy ticket for $209 per person are available. Travel duration is 1h 5m
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Lufthansa1h 0m06:45 AMFrankfurt am Main AirportFrankfurt am Main Airport7:45 AMBrussels AirportBrussels Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 11/6/2026 6:45:00 AM to Brussels Airport, Brussels Airport (Belgium) arriving at 11/6/2026 7:45:00 AM. 50 Economy ticket for $212 per person are available. Travel duration is 1h 0m
Cheapest Buses Friday
Cheapest Flights Friday
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Brussels Airlines1h 5m011:30 AMFrankfurt am Main AirportFrankfurt am Main Airport12:35 PMBrussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 11/7/2026 11:30:00 AM to Brussels Airport, Brussels Airport (Belgium) arriving at 11/7/2026 12:35:00 PM. 50 Economy ticket for $209 per person are available. Travel duration is 1h 5m
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Brussels Airlines1h 5m012:30 PMFrankfurt am Main AirportFrankfurt am Main Airport1:35 PMBrussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 11/7/2026 12:30:00 PM to Brussels Airport, Brussels Airport (Belgium) arriving at 11/7/2026 1:35:00 PM. 50 Economy ticket for $209 per person are available. Travel duration is 1h 5m
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Lufthansa1h 0m06:45 AMFrankfurt am Main AirportFrankfurt am Main Airport7:45 AMBrussels AirportBrussels Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 11/7/2026 6:45:00 AM to Brussels Airport, Brussels Airport (Belgium) arriving at 11/7/2026 7:45:00 AM. 50 Economy ticket for $212 per person are available. Travel duration is 1h 0m
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Brussels Airlines1h 10m09:00 AMFrankfurt am Main AirportFrankfurt am Main Airport10:10 AMBrussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 11/7/2026 9:00:00 AM to Brussels Airport, Brussels Airport (Belgium) arriving at 11/7/2026 10:10:00 AM. 50 Economy ticket for $212 per person are available. Travel duration is 1h 10m
Cheapest Flights Saturday
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FlixBus5h 50m012:05 PMMainzCentral Station5:55 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 11/8/2026 12:05:00 PM to North Station, Brussels (Belgium) arriving at 11/8/2026 5:55:00 PM. 50 Economy ticket for $27 per person are available. Travel duration is 5h 50m
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FlixBus8h 20m08:20 AMMainzCentral Station4:40 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 11/8/2026 8:20:00 AM to North Station, Brussels (Belgium) arriving at 11/8/2026 4:40:00 PM. 50 Economy ticket for $32 per person are available. Travel duration is 8h 20m
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BlaBlaCar Bus13h 48m012:25 PMFrankfurt am Main AirportFrankfurt am Main Airport2:13 AMBrusselsMidi Bus Station0EconomyA Bus from BlaBlaCar Bus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 11/8/2026 12:25:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 11/9/2026 2:13:00 AM. 50 Economy ticket for $84 per person are available. Travel duration is 13h 48m
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Lufthansa1h 0m06:45 AMFrankfurt am Main AirportFrankfurt am Main Airport7:45 AMBrussels AirportBrussels Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 11/8/2026 6:45:00 AM to Brussels Airport, Brussels Airport (Belgium) arriving at 11/8/2026 7:45:00 AM. 50 Economy ticket for $312 per person are available. Travel duration is 1h 0m
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Brussels Airlines1h 10m09:00 AMFrankfurt am Main AirportFrankfurt am Main Airport10:10 AMBrussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 11/8/2026 9:00:00 AM to Brussels Airport, Brussels Airport (Belgium) arriving at 11/8/2026 10:10:00 AM. 50 Economy ticket for $312 per person are available. Travel duration is 1h 10m
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Brussels Airlines1h 5m011:30 AMFrankfurt am Main AirportFrankfurt am Main Airport12:35 PMBrussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 11/8/2026 11:30:00 AM to Brussels Airport, Brussels Airport (Belgium) arriving at 11/8/2026 12:35:00 PM. 50 Economy ticket for $312 per person are available. Travel duration is 1h 5m
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Brussels Airlines1h 5m04:25 PMFrankfurt am Main AirportFrankfurt am Main Airport5:30 PMBrussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 11/8/2026 4:25:00 PM to Brussels Airport, Brussels Airport (Belgium) arriving at 11/8/2026 5:30:00 PM. 50 Economy ticket for $312 per person are available. Travel duration is 1h 5m
Cheapest Buses Sunday
Cheapest Flights Sunday
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Lufthansa1h 0m06:45 AMFrankfurt am Main AirportFrankfurt am Main Airport7:45 AMBrussels AirportBrussels Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 11/9/2026 6:45:00 AM to Brussels Airport, Brussels Airport (Belgium) arriving at 11/9/2026 7:45:00 AM. 50 Economy ticket for $321 per person are available. Travel duration is 1h 0m
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Brussels Airlines1h 10m09:00 AMFrankfurt am Main AirportFrankfurt am Main Airport10:10 AMBrussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 11/9/2026 9:00:00 AM to Brussels Airport, Brussels Airport (Belgium) arriving at 11/9/2026 10:10:00 AM. 50 Economy ticket for $321 per person are available. Travel duration is 1h 10m
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Brussels Airlines1h 5m011:30 AMFrankfurt am Main AirportFrankfurt am Main Airport12:35 PMBrussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 11/9/2026 11:30:00 AM to Brussels Airport, Brussels Airport (Belgium) arriving at 11/9/2026 12:35:00 PM. 50 Economy ticket for $321 per person are available. Travel duration is 1h 5m
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Brussels Airlines1h 5m012:30 PMFrankfurt am Main AirportFrankfurt am Main Airport1:35 PMBrussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 11/9/2026 12:30:00 PM to Brussels Airport, Brussels Airport (Belgium) arriving at 11/9/2026 1:35:00 PM. 50 Economy ticket for $321 per person are available. Travel duration is 1h 5m
Cheapest Flights Monday
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Lufthansa25h 10m01:10 PMFrankfurt am Main AirportFrankfurt am Main Airport2:20 PMAntwerp AirportAntwerp Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 11/10/2026 1:10:00 PM to Antwerp Airport, Antwerp Airport (Belgium) arriving at 11/11/2026 2:20:00 PM. 50 Economy ticket for $462 per person are available. Travel duration is 25h 10m
Cheapest Flights Tuesday
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Deutsche Bahn4h 47m07:00 PMMainzCentral Station11:47 PMBrusselsCentral Station0EconomyA Train from Deutsche Bahn goes from Central Station, Mainz (Germany) at 11/11/2026 7:00:00 PM to Central Station, Brussels (Belgium) arriving at 11/11/2026 11:47:00 PM. 50 Economy ticket for $55 per person are available. Travel duration is 4h 47m
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Deutsche Bahn2h 59m06:48 AMFrankfurt am Main AirportFrankfurt am Main Airport Train Station9:47 AMBrusselsCentral Station0EconomyA Train from Deutsche Bahn goes from Frankfurt am Main Airport Train Station, Frankfurt am Main Airport (Germany) at 11/11/2026 6:48:00 AM to Central Station, Brussels (Belgium) arriving at 11/11/2026 9:47:00 AM. 50 Economy ticket for $56 per person are available. Travel duration is 2h 59m
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Deutsche Bahn5h 10m06:37 PMFrankfurt am Main AirportFrankfurt am Main Airport Train Station11:47 PMBrusselsCentral Station0EconomyA Train from Deutsche Bahn goes from Frankfurt am Main Airport Train Station, Frankfurt am Main Airport (Germany) at 11/11/2026 6:37:00 PM to Central Station, Brussels (Belgium) arriving at 11/11/2026 11:47:00 PM. 50 Economy ticket for $57 per person are available. Travel duration is 5h 10m
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Deutsche Bahn2h 59m08:48 AMFrankfurt am Main AirportFrankfurt am Main Airport Train Station11:47 AMBrusselsCentral Station0EconomyA Train from Deutsche Bahn goes from Frankfurt am Main Airport Train Station, Frankfurt am Main Airport (Germany) at 11/11/2026 8:48:00 AM to Central Station, Brussels (Belgium) arriving at 11/11/2026 11:47:00 AM. 50 Economy ticket for $60 per person are available. Travel duration is 2h 59m
Cheapest Trains Wednesday
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FlixBus5h 50m012:05 PMMainzCentral Station5:55 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 11/12/2026 12:05:00 PM to North Station, Brussels (Belgium) arriving at 11/12/2026 5:55:00 PM. 50 Economy ticket for $26 per person are available. Travel duration is 5h 50m
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Lufthansa1h 0m06:45 AMFrankfurt am Main AirportFrankfurt am Main Airport7:45 AMBrussels AirportBrussels Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 11/12/2026 6:45:00 AM to Brussels Airport, Brussels Airport (Belgium) arriving at 11/12/2026 7:45:00 AM. 50 Economy ticket for $167 per person are available. Travel duration is 1h 0m
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Brussels Airlines1h 10m09:00 AMFrankfurt am Main AirportFrankfurt am Main Airport10:10 AMBrussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 11/12/2026 9:00:00 AM to Brussels Airport, Brussels Airport (Belgium) arriving at 11/12/2026 10:10:00 AM. 50 Economy ticket for $171 per person are available. Travel duration is 1h 10m
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Brussels Airlines1h 5m011:30 AMFrankfurt am Main AirportFrankfurt am Main Airport12:35 PMBrussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 11/12/2026 11:30:00 AM to Brussels Airport, Brussels Airport (Belgium) arriving at 11/12/2026 12:35:00 PM. 50 Economy ticket for $171 per person are available. Travel duration is 1h 5m
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Brussels Airlines1h 5m012:30 PMFrankfurt am Main AirportFrankfurt am Main Airport1:35 PMBrussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 11/12/2026 12:30:00 PM to Brussels Airport, Brussels Airport (Belgium) arriving at 11/12/2026 1:35:00 PM. 50 Economy ticket for $171 per person are available. Travel duration is 1h 5m
Cheapest Buses Thursday
Cheapest Flights Thursday
What are the fastest trips from Mainz to Brussels?
You can get to Brussels from Mainz in just 1h 0m with a Flight from Lufthansa. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.
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Lufthansa1h 0m06:45 AMFrankfurt am Main AirportFrankfurt am Main Airport7:45 AMBrussels AirportBrussels Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 11/6/2026 6:45:00 AM to Brussels Airport, Brussels Airport (Belgium) arriving at 11/6/2026 7:45:00 AM. 50 Economy ticket for $212 per person are available. Travel duration is 1h 0m
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Brussels Airlines1h 5m011:30 AMFrankfurt am Main AirportFrankfurt am Main Airport12:35 PMBrussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 11/6/2026 11:30:00 AM to Brussels Airport, Brussels Airport (Belgium) arriving at 11/6/2026 12:35:00 PM. 50 Economy ticket for $209 per person are available. Travel duration is 1h 5m
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Brussels Airlines1h 5m012:30 PMFrankfurt am Main AirportFrankfurt am Main Airport1:35 PMBrussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 11/6/2026 12:30:00 PM to Brussels Airport, Brussels Airport (Belgium) arriving at 11/6/2026 1:35:00 PM. 50 Economy ticket for $209 per person are available. Travel duration is 1h 5m
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Brussels Airlines1h 5m04:25 PMFrankfurt am Main AirportFrankfurt am Main Airport5:30 PMBrussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 11/6/2026 4:25:00 PM to Brussels Airport, Brussels Airport (Belgium) arriving at 11/6/2026 5:30:00 PM. 50 Economy ticket for $209 per person are available. Travel duration is 1h 5m
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FlixBus5h 50m012:05 PMMainzCentral Station5:55 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 11/6/2026 12:05:00 PM to North Station, Brussels (Belgium) arriving at 11/6/2026 5:55:00 PM. 50 Economy ticket for $25 per person are available. Travel duration is 5h 50m
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FlixBus8h 25m08:15 AMMainzCentral Station4:40 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 11/6/2026 8:15:00 AM to North Station, Brussels (Belgium) arriving at 11/6/2026 4:40:00 PM. 50 Economy ticket for $32 per person are available. Travel duration is 8h 25m
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FlixBus9h 15m011:00 AMFrankfurt am Main AirportFrankfurt am Main Airport8:15 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 11/6/2026 11:00:00 AM to North Station, Brussels (Belgium) arriving at 11/6/2026 8:15:00 PM. 50 Economy ticket for $34 per person are available. Travel duration is 9h 15m
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BlaBlaCar Bus13h 48m012:25 PMFrankfurt am Main AirportFrankfurt am Main Airport2:13 AMBrusselsMidi Bus Station0EconomyA Bus from BlaBlaCar Bus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 11/6/2026 12:25:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 11/7/2026 2:13:00 AM. 50 Economy ticket for $118 per person are available. Travel duration is 13h 48m
Fastest Flights Friday
Fastest Buses Friday
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Lufthansa1h 0m06:45 AMFrankfurt am Main AirportFrankfurt am Main Airport7:45 AMBrussels AirportBrussels Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 11/7/2026 6:45:00 AM to Brussels Airport, Brussels Airport (Belgium) arriving at 11/7/2026 7:45:00 AM. 50 Economy ticket for $212 per person are available. Travel duration is 1h 0m
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Brussels Airlines1h 5m011:30 AMFrankfurt am Main AirportFrankfurt am Main Airport12:35 PMBrussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 11/7/2026 11:30:00 AM to Brussels Airport, Brussels Airport (Belgium) arriving at 11/7/2026 12:35:00 PM. 50 Economy ticket for $209 per person are available. Travel duration is 1h 5m
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Brussels Airlines1h 5m012:30 PMFrankfurt am Main AirportFrankfurt am Main Airport1:35 PMBrussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 11/7/2026 12:30:00 PM to Brussels Airport, Brussels Airport (Belgium) arriving at 11/7/2026 1:35:00 PM. 50 Economy ticket for $209 per person are available. Travel duration is 1h 5m
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Brussels Airlines1h 10m09:00 AMFrankfurt am Main AirportFrankfurt am Main Airport10:10 AMBrussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 11/7/2026 9:00:00 AM to Brussels Airport, Brussels Airport (Belgium) arriving at 11/7/2026 10:10:00 AM. 50 Economy ticket for $212 per person are available. Travel duration is 1h 10m
Fastest Flights Saturday
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Lufthansa1h 0m06:45 AMFrankfurt am Main AirportFrankfurt am Main Airport7:45 AMBrussels AirportBrussels Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 11/8/2026 6:45:00 AM to Brussels Airport, Brussels Airport (Belgium) arriving at 11/8/2026 7:45:00 AM. 50 Economy ticket for $312 per person are available. Travel duration is 1h 0m
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Brussels Airlines1h 5m011:30 AMFrankfurt am Main AirportFrankfurt am Main Airport12:35 PMBrussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 11/8/2026 11:30:00 AM to Brussels Airport, Brussels Airport (Belgium) arriving at 11/8/2026 12:35:00 PM. 50 Economy ticket for $312 per person are available. Travel duration is 1h 5m
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Brussels Airlines1h 5m04:25 PMFrankfurt am Main AirportFrankfurt am Main Airport5:30 PMBrussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 11/8/2026 4:25:00 PM to Brussels Airport, Brussels Airport (Belgium) arriving at 11/8/2026 5:30:00 PM. 50 Economy ticket for $312 per person are available. Travel duration is 1h 5m
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Brussels Airlines1h 10m09:00 AMFrankfurt am Main AirportFrankfurt am Main Airport10:10 AMBrussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 11/8/2026 9:00:00 AM to Brussels Airport, Brussels Airport (Belgium) arriving at 11/8/2026 10:10:00 AM. 50 Economy ticket for $312 per person are available. Travel duration is 1h 10m
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FlixBus5h 50m012:05 PMMainzCentral Station5:55 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 11/8/2026 12:05:00 PM to North Station, Brussels (Belgium) arriving at 11/8/2026 5:55:00 PM. 50 Economy ticket for $27 per person are available. Travel duration is 5h 50m
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FlixBus8h 20m08:20 AMMainzCentral Station4:40 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 11/8/2026 8:20:00 AM to North Station, Brussels (Belgium) arriving at 11/8/2026 4:40:00 PM. 50 Economy ticket for $32 per person are available. Travel duration is 8h 20m
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BlaBlaCar Bus13h 48m012:25 PMFrankfurt am Main AirportFrankfurt am Main Airport2:13 AMBrusselsMidi Bus Station0EconomyA Bus from BlaBlaCar Bus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 11/8/2026 12:25:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 11/9/2026 2:13:00 AM. 50 Economy ticket for $84 per person are available. Travel duration is 13h 48m
Fastest Flights Sunday
Fastest Buses Sunday
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Lufthansa1h 0m06:45 AMFrankfurt am Main AirportFrankfurt am Main Airport7:45 AMBrussels AirportBrussels Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 11/9/2026 6:45:00 AM to Brussels Airport, Brussels Airport (Belgium) arriving at 11/9/2026 7:45:00 AM. 50 Economy ticket for $321 per person are available. Travel duration is 1h 0m
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Brussels Airlines1h 5m011:30 AMFrankfurt am Main AirportFrankfurt am Main Airport12:35 PMBrussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 11/9/2026 11:30:00 AM to Brussels Airport, Brussels Airport (Belgium) arriving at 11/9/2026 12:35:00 PM. 50 Economy ticket for $321 per person are available. Travel duration is 1h 5m
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Brussels Airlines1h 5m012:30 PMFrankfurt am Main AirportFrankfurt am Main Airport1:35 PMBrussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 11/9/2026 12:30:00 PM to Brussels Airport, Brussels Airport (Belgium) arriving at 11/9/2026 1:35:00 PM. 50 Economy ticket for $321 per person are available. Travel duration is 1h 5m
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Brussels Airlines1h 10m09:00 AMFrankfurt am Main AirportFrankfurt am Main Airport10:10 AMBrussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 11/9/2026 9:00:00 AM to Brussels Airport, Brussels Airport (Belgium) arriving at 11/9/2026 10:10:00 AM. 50 Economy ticket for $321 per person are available. Travel duration is 1h 10m
Fastest Flights Monday
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Lufthansa25h 10m01:10 PMFrankfurt am Main AirportFrankfurt am Main Airport2:20 PMAntwerp AirportAntwerp Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 11/10/2026 1:10:00 PM to Antwerp Airport, Antwerp Airport (Belgium) arriving at 11/11/2026 2:20:00 PM. 50 Economy ticket for $462 per person are available. Travel duration is 25h 10m
Fastest Flights Tuesday
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Deutsche Bahn2h 59m06:48 AMFrankfurt am Main AirportFrankfurt am Main Airport Train Station9:47 AMBrusselsCentral Station0EconomyA Train from Deutsche Bahn goes from Frankfurt am Main Airport Train Station, Frankfurt am Main Airport (Germany) at 11/11/2026 6:48:00 AM to Central Station, Brussels (Belgium) arriving at 11/11/2026 9:47:00 AM. 50 Economy ticket for $56 per person are available. Travel duration is 2h 59m
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Deutsche Bahn2h 59m08:48 AMFrankfurt am Main AirportFrankfurt am Main Airport Train Station11:47 AMBrusselsCentral Station0EconomyA Train from Deutsche Bahn goes from Frankfurt am Main Airport Train Station, Frankfurt am Main Airport (Germany) at 11/11/2026 8:48:00 AM to Central Station, Brussels (Belgium) arriving at 11/11/2026 11:47:00 AM. 50 Economy ticket for $60 per person are available. Travel duration is 2h 59m
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Deutsche Bahn3h 18m08:29 PMFrankfurt am Main AirportFrankfurt am Main Airport Train Station11:47 PMBrusselsCentral Station0EconomyA Train from Deutsche Bahn goes from Frankfurt am Main Airport Train Station, Frankfurt am Main Airport (Germany) at 11/11/2026 8:29:00 PM to Central Station, Brussels (Belgium) arriving at 11/11/2026 11:47:00 PM. 50 Economy ticket for $60 per person are available. Travel duration is 3h 18m
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Deutsche Bahn4h 47m07:00 PMMainzCentral Station11:47 PMBrusselsCentral Station0EconomyA Train from Deutsche Bahn goes from Central Station, Mainz (Germany) at 11/11/2026 7:00:00 PM to Central Station, Brussels (Belgium) arriving at 11/11/2026 11:47:00 PM. 50 Economy ticket for $55 per person are available. Travel duration is 4h 47m
Fastest Trains Wednesday
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Lufthansa1h 0m06:45 AMFrankfurt am Main AirportFrankfurt am Main Airport7:45 AMBrussels AirportBrussels Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 11/12/2026 6:45:00 AM to Brussels Airport, Brussels Airport (Belgium) arriving at 11/12/2026 7:45:00 AM. 50 Economy ticket for $167 per person are available. Travel duration is 1h 0m
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Brussels Airlines1h 5m011:30 AMFrankfurt am Main AirportFrankfurt am Main Airport12:35 PMBrussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 11/12/2026 11:30:00 AM to Brussels Airport, Brussels Airport (Belgium) arriving at 11/12/2026 12:35:00 PM. 50 Economy ticket for $171 per person are available. Travel duration is 1h 5m
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Brussels Airlines1h 5m012:30 PMFrankfurt am Main AirportFrankfurt am Main Airport1:35 PMBrussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 11/12/2026 12:30:00 PM to Brussels Airport, Brussels Airport (Belgium) arriving at 11/12/2026 1:35:00 PM. 50 Economy ticket for $171 per person are available. Travel duration is 1h 5m
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Brussels Airlines1h 10m09:00 AMFrankfurt am Main AirportFrankfurt am Main Airport10:10 AMBrussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 11/12/2026 9:00:00 AM to Brussels Airport, Brussels Airport (Belgium) arriving at 11/12/2026 10:10:00 AM. 50 Economy ticket for $171 per person are available. Travel duration is 1h 10m
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FlixBus5h 50m012:05 PMMainzCentral Station5:55 PMBrusselsNorth Station0EconomyA Bus from FlixBus goes from Central Station, Mainz (Germany) at 11/12/2026 12:05:00 PM to North Station, Brussels (Belgium) arriving at 11/12/2026 5:55:00 PM. 50 Economy ticket for $26 per person are available. Travel duration is 5h 50m
Fastest Flights Thursday
Fastest Buses Thursday
Here you will find all operators and timetables for a
Bus from Mainz to Brussels
What are the most popular stations in Mainz and Brussels?
In Mainz, you will usually depart from Central Station, Central Bus Station or Laubenheim Train Station, while in Brussels you will be arriving at North Station, Midi Bus Station or Gare Centrale, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Brussels from Mainz? With 5 connections between 2 Flight, Train and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Mainz and Brussels, you can pay as low as $25 with a Bus from FlixBus.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Lufthansa: you will get to Brussels in just 1h 0m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Mainz and Brussels are Brussels Airlines, Lufthansa and FlixBus, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Mainz and Brussels is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Budenheim or to Saint-Gilles, and look at flights from Frankfurt am Main Airport, and landing at Brussels South Charleroi Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Mainz to Brussels?
The most popular companies between Mainz and Brussels, are Brussels Airlines, Lufthansa and FlixBus. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: FlixBus and BlaBlaCar Bus
Train companies: Deutsche Bahn
Airlines: Brussels Airlines and Lufthansa
All you need to know when you travel from Mainz to Brussels
Check all information on comfort and services on all modes of transports from Mainz to Brussels. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Mainz to Brussels
How can I reach Brussels from Mainz?
Every day, there are on average 5 connections between Flight, Train and Bus, with which you can get to Brussels from Mainz.
How far is Brussels from Mainz?
The distance between Mainz and Brussels is 181.5 miles.
What is the most ecofriendly mode of transport between Mainz and Brussels?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 8 kgs of CO2, a train 10 kgs, a car 50 kgs, and a flight 72 kgs.
What is the cheapest mode of transport from Mainz to Brussels?
You can get to Brussels with just $25 by taking a Bus from FlixBus.
What is the fastest way to get from Mainz to Brussels?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Brussels in just 1h 0m with a Flight from Lufthansa.
More routes to Mainz and to Brussels
Looking for more options? Here you can see the most popular routes to Mainz and to Brussels. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Mainz
- Amsterdam to Mainz
- Berlin to Mainz
- Brussels to Mainz
- Frankfurt Hahn Airport to Mainz
- Kaiserslautern to Mainz
- Koblenz to Mainz
- Paris to Mainz
- Simmern (Hunsrück) to Mainz
- Trips to Brussels
- Algeciras to Brussels
- Amsterdam to Brussels
- Antwerp to Brussels
- Barcelona to Brussels
- Bern to Brussels
- Bremen to Brussels
- Brussels South Charleroi Airport to Brussels
- Budapest to Brussels
- Cologne to Brussels
- Cologne/Bonn Airport to Brussels
- Genoa to Brussels
- Ghent to Brussels
- Hamburg to Brussels
- London to Brussels
- Marseille to Brussels
- Milan to Brussels
- Paris Charles de Gaulle Airport to Brussels
- Paris Orly Airport to Brussels
- Paris to Brussels
- Salzburg to Brussels
- Stuttgart to Brussels
- The Hague to Brussels
- Vianen to Brussels
- Vienna to Brussels
