What is the best way to travel from Mainz to Brussels?
Looking for a trip? Compare all the available Flights, Trains and Buses for the journey to Brussels from Mainz. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 1 available companies to find your perfect trip!
What is the cheapest way to reach Brussels from Mainz?
You can get to Brussels with just $39 by taking a Train from Deutsche Bahn, but you can find many more cheap offers: we have selected the best ones for next few days here for you.
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Brussels Airlines1h 5m012:30 PMFrankfurt am Main AirportFrankfurt am Main Airport1:35 PMBrussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 3/17/2026 12:30:00 PM to Brussels Airport, Brussels Airport (Belgium) arriving at 3/17/2026 1:35:00 PM. 50 Economy ticket for $324 per person are available. Travel duration is 1h 5m
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Brussels Airlines1h 5m04:25 PMFrankfurt am Main AirportFrankfurt am Main Airport5:30 PMBrussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 3/17/2026 4:25:00 PM to Brussels Airport, Brussels Airport (Belgium) arriving at 3/17/2026 5:30:00 PM. 50 Economy ticket for $324 per person are available. Travel duration is 1h 5m
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Brussels Airlines1h 5m07:35 PMFrankfurt am Main AirportFrankfurt am Main Airport8:40 PMBrussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 3/17/2026 7:35:00 PM to Brussels Airport, Brussels Airport (Belgium) arriving at 3/17/2026 8:40:00 PM. 50 Economy ticket for $324 per person are available. Travel duration is 1h 5m
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Lufthansa1h 5m04:25 PMFrankfurt am Main AirportFrankfurt am Main Airport5:30 PMBrussels AirportBrussels Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 3/17/2026 4:25:00 PM to Brussels Airport, Brussels Airport (Belgium) arriving at 3/17/2026 5:30:00 PM. 50 Economy ticket for $696 per person are available. Travel duration is 1h 5m
Cheapest Flights Tuesday
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EasyJet Airline23h 30m09:10 AMFrankfurt am Main AirportFrankfurt am Main Airport8:40 AMBrussels AirportBrussels Airport0EconomyA Flight from EasyJet Airline goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 3/19/2026 9:10:00 AM to Brussels Airport, Brussels Airport (Belgium) arriving at 3/20/2026 8:40:00 AM. 50 Economy ticket for $130 per person are available. Travel duration is 23h 30m
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Lufthansa23h 0m08:50 AMFrankfurt am Main AirportFrankfurt am Main Airport7:50 AMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 3/19/2026 8:50:00 AM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 3/20/2026 7:50:00 AM. 50 Economy ticket for $168 per person are available. Travel duration is 23h 0m
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Lufthansa11h 55m09:40 PMFrankfurt am Main AirportFrankfurt am Main Airport9:35 AMBrussels AirportBrussels Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 3/19/2026 9:40:00 PM to Brussels Airport, Brussels Airport (Belgium) arriving at 3/20/2026 9:35:00 AM. 50 Economy ticket for $176 per person are available. Travel duration is 11h 55m
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Aer Lingus13h 35m08:00 PMFrankfurt am Main AirportFrankfurt am Main Airport9:35 AMBrussels AirportBrussels Airport0EconomyA Flight from Aer Lingus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 3/19/2026 8:00:00 PM to Brussels Airport, Brussels Airport (Belgium) arriving at 3/20/2026 9:35:00 AM. 50 Economy ticket for $177 per person are available. Travel duration is 13h 35m
Cheapest Flights Thursday
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BlaBlaCar Bus13h 48m012:25 PMFrankfurt am Main AirportFrankfurt am Main Airport2:13 AMBrusselsMidi Bus Station0EconomyA Bus from BlaBlaCar Bus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 3/20/2026 12:25:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 3/21/2026 2:13:00 AM. 50 Economy ticket for $63 per person are available. Travel duration is 13h 48m
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Lufthansa1h 0m07:20 AMFrankfurt am Main AirportFrankfurt am Main Airport8:20 AMBrussels AirportBrussels Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 3/20/2026 7:20:00 AM to Brussels Airport, Brussels Airport (Belgium) arriving at 3/20/2026 8:20:00 AM. 50 Economy ticket for $285 per person are available. Travel duration is 1h 0m
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Brussels Airlines1h 5m011:30 AMFrankfurt am Main AirportFrankfurt am Main Airport12:35 PMBrussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 3/20/2026 11:30:00 AM to Brussels Airport, Brussels Airport (Belgium) arriving at 3/20/2026 12:35:00 PM. 50 Economy ticket for $294 per person are available. Travel duration is 1h 5m
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Brussels Airlines1h 5m07:35 PMFrankfurt am Main AirportFrankfurt am Main Airport8:40 PMBrussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 3/20/2026 7:35:00 PM to Brussels Airport, Brussels Airport (Belgium) arriving at 3/20/2026 8:40:00 PM. 50 Economy ticket for $313 per person are available. Travel duration is 1h 5m
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Brussels Airlines1h 5m012:30 PMFrankfurt am Main AirportFrankfurt am Main Airport1:35 PMBrussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 3/20/2026 12:30:00 PM to Brussels Airport, Brussels Airport (Belgium) arriving at 3/20/2026 1:35:00 PM. 50 Economy ticket for $317 per person are available. Travel duration is 1h 5m
Cheapest Buses Friday
Cheapest Flights Friday
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EasyJet Airline13h 15m07:25 PMFrankfurt am Main AirportFrankfurt am Main Airport8:40 AMBrussels AirportBrussels Airport0EconomyA Flight from EasyJet Airline goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 3/21/2026 7:25:00 PM to Brussels Airport, Brussels Airport (Belgium) arriving at 3/22/2026 8:40:00 AM. 50 Economy ticket for $123 per person are available. Travel duration is 13h 15m
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Lufthansa11h 55m08:45 PMFrankfurt am Main AirportFrankfurt am Main Airport8:40 AMBrussels AirportBrussels Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 3/21/2026 8:45:00 PM to Brussels Airport, Brussels Airport (Belgium) arriving at 3/22/2026 8:40:00 AM. 50 Economy ticket for $154 per person are available. Travel duration is 11h 55m
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Lufthansa25h 30m06:50 AMFrankfurt am Main AirportFrankfurt am Main Airport8:20 AMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 3/21/2026 6:50:00 AM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 3/22/2026 8:20:00 AM. 50 Economy ticket for $193 per person are available. Travel duration is 25h 30m
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Brussels Airlines1h 10m09:00 AMFrankfurt am Main AirportFrankfurt am Main Airport10:10 AMBrussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 3/21/2026 9:00:00 AM to Brussels Airport, Brussels Airport (Belgium) arriving at 3/21/2026 10:10:00 AM. 50 Economy ticket for $193 per person are available. Travel duration is 1h 10m
Cheapest Flights Saturday
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Deutsche Bahn9h 24m07:20 PMMainzCentral Station4:44 AMBrusselsCentral Station0EconomyA Train from Deutsche Bahn goes from Central Station, Mainz (Germany) at 3/22/2026 7:20:00 PM to Central Station, Brussels (Belgium) arriving at 3/23/2026 4:44:00 AM. 50 Economy ticket for $57 per person are available. Travel duration is 9h 24m
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BlaBlaCar Bus13h 48m012:25 PMFrankfurt am Main AirportFrankfurt am Main Airport2:13 AMBrusselsMidi Bus Station0EconomyA Bus from BlaBlaCar Bus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 3/22/2026 12:25:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 3/23/2026 2:13:00 AM. 50 Economy ticket for $75 per person are available. Travel duration is 13h 48m
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Lufthansa1h 0m07:20 AMFrankfurt am Main AirportFrankfurt am Main Airport8:20 AMBrussels AirportBrussels Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 3/22/2026 7:20:00 AM to Brussels Airport, Brussels Airport (Belgium) arriving at 3/22/2026 8:20:00 AM. 50 Economy ticket for $193 per person are available. Travel duration is 1h 0m
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Brussels Airlines1h 10m09:00 AMFrankfurt am Main AirportFrankfurt am Main Airport10:10 AMBrussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 3/22/2026 9:00:00 AM to Brussels Airport, Brussels Airport (Belgium) arriving at 3/22/2026 10:10:00 AM. 50 Economy ticket for $193 per person are available. Travel duration is 1h 10m
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Brussels Airlines1h 5m011:30 AMFrankfurt am Main AirportFrankfurt am Main Airport12:35 PMBrussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 3/22/2026 11:30:00 AM to Brussels Airport, Brussels Airport (Belgium) arriving at 3/22/2026 12:35:00 PM. 50 Economy ticket for $193 per person are available. Travel duration is 1h 5m
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Brussels Airlines1h 5m04:25 PMFrankfurt am Main AirportFrankfurt am Main Airport5:30 PMBrussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 3/22/2026 4:25:00 PM to Brussels Airport, Brussels Airport (Belgium) arriving at 3/22/2026 5:30:00 PM. 50 Economy ticket for $193 per person are available. Travel duration is 1h 5m
Cheapest Trains Sunday
Cheapest Buses Sunday
Cheapest Flights Sunday
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Deutsche Bahn3h 46m08:29 PMFrankfurt am Main AirportFrankfurt am Main Airport Train Station12:15 AMBrusselsCentral Station0EconomyA Train from Deutsche Bahn goes from Frankfurt am Main Airport Train Station, Frankfurt am Main Airport (Germany) at 3/23/2026 8:29:00 PM to Central Station, Brussels (Belgium) arriving at 3/24/2026 12:15:00 AM. 50 Economy ticket for $39 per person are available. Travel duration is 3h 46m
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Deutsche Bahn2h 56m06:48 PMFrankfurt am Main AirportFrankfurt am Main Airport Train Station9:44 PMBrusselsCentral Station0EconomyA Train from Deutsche Bahn goes from Frankfurt am Main Airport Train Station, Frankfurt am Main Airport (Germany) at 3/23/2026 6:48:00 PM to Central Station, Brussels (Belgium) arriving at 3/23/2026 9:44:00 PM. 50 Economy ticket for $48 per person are available. Travel duration is 2h 56m
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Deutsche Bahn3h 27m06:48 PMFrankfurt am Main AirportFrankfurt am Main Airport Train Station10:15 PMBrusselsCentral Station0EconomyA Train from Deutsche Bahn goes from Frankfurt am Main Airport Train Station, Frankfurt am Main Airport (Germany) at 3/23/2026 6:48:00 PM to Central Station, Brussels (Belgium) arriving at 3/23/2026 10:15:00 PM. 50 Economy ticket for $48 per person are available. Travel duration is 3h 27m
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Deutsche Bahn2h 56m06:48 AMFrankfurt am Main AirportFrankfurt am Main Airport Train Station9:44 AMBrusselsCentral Station0EconomyA Train from Deutsche Bahn goes from Frankfurt am Main Airport Train Station, Frankfurt am Main Airport (Germany) at 3/23/2026 6:48:00 AM to Central Station, Brussels (Belgium) arriving at 3/23/2026 9:44:00 AM. 50 Economy ticket for $62 per person are available. Travel duration is 2h 56m
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Brussels Airlines1h 5m011:30 AMFrankfurt am Main AirportFrankfurt am Main Airport12:35 PMBrussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 3/23/2026 11:30:00 AM to Brussels Airport, Brussels Airport (Belgium) arriving at 3/23/2026 12:35:00 PM. 50 Economy ticket for $192 per person are available. Travel duration is 1h 5m
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Brussels Airlines1h 5m012:30 PMFrankfurt am Main AirportFrankfurt am Main Airport1:35 PMBrussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 3/23/2026 12:30:00 PM to Brussels Airport, Brussels Airport (Belgium) arriving at 3/23/2026 1:35:00 PM. 50 Economy ticket for $192 per person are available. Travel duration is 1h 5m
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Brussels Airlines1h 0m09:30 PMFrankfurt am Main AirportFrankfurt am Main Airport10:30 PMBrussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 3/23/2026 9:30:00 PM to Brussels Airport, Brussels Airport (Belgium) arriving at 3/23/2026 10:30:00 PM. 50 Economy ticket for $192 per person are available. Travel duration is 1h 0m
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Lufthansa1h 0m07:20 AMFrankfurt am Main AirportFrankfurt am Main Airport8:20 AMBrussels AirportBrussels Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 3/23/2026 7:20:00 AM to Brussels Airport, Brussels Airport (Belgium) arriving at 3/23/2026 8:20:00 AM. 50 Economy ticket for $193 per person are available. Travel duration is 1h 0m
Cheapest Trains Monday
Cheapest Flights Monday
What are the fastest trips from Mainz to Brussels?
You can get to Brussels from Mainz in just 1h 0m with a Flight from Lufthansa. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.
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Brussels Airlines1h 5m012:30 PMFrankfurt am Main AirportFrankfurt am Main Airport1:35 PMBrussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 3/17/2026 12:30:00 PM to Brussels Airport, Brussels Airport (Belgium) arriving at 3/17/2026 1:35:00 PM. 50 Economy ticket for $324 per person are available. Travel duration is 1h 5m
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Brussels Airlines1h 5m04:25 PMFrankfurt am Main AirportFrankfurt am Main Airport5:30 PMBrussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 3/17/2026 4:25:00 PM to Brussels Airport, Brussels Airport (Belgium) arriving at 3/17/2026 5:30:00 PM. 50 Economy ticket for $324 per person are available. Travel duration is 1h 5m
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Brussels Airlines1h 5m07:35 PMFrankfurt am Main AirportFrankfurt am Main Airport8:40 PMBrussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 3/17/2026 7:35:00 PM to Brussels Airport, Brussels Airport (Belgium) arriving at 3/17/2026 8:40:00 PM. 50 Economy ticket for $324 per person are available. Travel duration is 1h 5m
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Lufthansa1h 5m04:25 PMFrankfurt am Main AirportFrankfurt am Main Airport5:30 PMBrussels AirportBrussels Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 3/17/2026 4:25:00 PM to Brussels Airport, Brussels Airport (Belgium) arriving at 3/17/2026 5:30:00 PM. 50 Economy ticket for $696 per person are available. Travel duration is 1h 5m
Fastest Flights Tuesday
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TAROM6h 15m011:15 AMFrankfurt am Main AirportFrankfurt am Main Airport5:30 PMBrussels AirportBrussels Airport0EconomyA Flight from TAROM goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 3/19/2026 11:15:00 AM to Brussels Airport, Brussels Airport (Belgium) arriving at 3/19/2026 5:30:00 PM. 50 Economy ticket for $186 per person are available. Travel duration is 6h 15m
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Lufthansa8h 10m07:45 AMFrankfurt am Main AirportFrankfurt am Main Airport3:55 PMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 3/19/2026 7:45:00 AM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 3/19/2026 3:55:00 PM. 50 Economy ticket for $296 per person are available. Travel duration is 8h 10m
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Lufthansa8h 45m010:35 AMFrankfurt am Main AirportFrankfurt am Main Airport7:20 PMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 3/19/2026 10:35:00 AM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 3/19/2026 7:20:00 PM. 50 Economy ticket for $202 per person are available. Travel duration is 8h 45m
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Lufthansa11h 25m08:55 PMFrankfurt am Main AirportFrankfurt am Main Airport8:20 AMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 3/19/2026 8:55:00 PM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 3/20/2026 8:20:00 AM. 50 Economy ticket for $205 per person are available. Travel duration is 11h 25m
Fastest Flights Thursday
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Lufthansa1h 0m07:20 AMFrankfurt am Main AirportFrankfurt am Main Airport8:20 AMBrussels AirportBrussels Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 3/20/2026 7:20:00 AM to Brussels Airport, Brussels Airport (Belgium) arriving at 3/20/2026 8:20:00 AM. 50 Economy ticket for $285 per person are available. Travel duration is 1h 0m
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Brussels Airlines1h 5m011:30 AMFrankfurt am Main AirportFrankfurt am Main Airport12:35 PMBrussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 3/20/2026 11:30:00 AM to Brussels Airport, Brussels Airport (Belgium) arriving at 3/20/2026 12:35:00 PM. 50 Economy ticket for $294 per person are available. Travel duration is 1h 5m
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Brussels Airlines1h 5m07:35 PMFrankfurt am Main AirportFrankfurt am Main Airport8:40 PMBrussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 3/20/2026 7:35:00 PM to Brussels Airport, Brussels Airport (Belgium) arriving at 3/20/2026 8:40:00 PM. 50 Economy ticket for $313 per person are available. Travel duration is 1h 5m
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Brussels Airlines1h 5m012:30 PMFrankfurt am Main AirportFrankfurt am Main Airport1:35 PMBrussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 3/20/2026 12:30:00 PM to Brussels Airport, Brussels Airport (Belgium) arriving at 3/20/2026 1:35:00 PM. 50 Economy ticket for $317 per person are available. Travel duration is 1h 5m
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BlaBlaCar Bus13h 48m012:25 PMFrankfurt am Main AirportFrankfurt am Main Airport2:13 AMBrusselsMidi Bus Station0EconomyA Bus from BlaBlaCar Bus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 3/20/2026 12:25:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 3/21/2026 2:13:00 AM. 50 Economy ticket for $63 per person are available. Travel duration is 13h 48m
Fastest Flights Friday
Fastest Buses Friday
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Brussels Airlines1h 10m09:00 AMFrankfurt am Main AirportFrankfurt am Main Airport10:10 AMBrussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 3/21/2026 9:00:00 AM to Brussels Airport, Brussels Airport (Belgium) arriving at 3/21/2026 10:10:00 AM. 50 Economy ticket for $193 per person are available. Travel duration is 1h 10m
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Lufthansa5h 55m010:00 AMFrankfurt am Main AirportFrankfurt am Main Airport3:55 PMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 3/21/2026 10:00:00 AM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 3/21/2026 3:55:00 PM. 50 Economy ticket for $278 per person are available. Travel duration is 5h 55m
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Lufthansa8h 10m07:45 AMFrankfurt am Main AirportFrankfurt am Main Airport3:55 PMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 3/21/2026 7:45:00 AM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 3/21/2026 3:55:00 PM. 50 Economy ticket for $216 per person are available. Travel duration is 8h 10m
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Lufthansa11h 20m09:00 PMFrankfurt am Main AirportFrankfurt am Main Airport8:20 AMBrussels South Charleroi AirportBrussels South Charleroi Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 3/21/2026 9:00:00 PM to Brussels South Charleroi Airport, Brussels South Charleroi Airport (Belgium) arriving at 3/22/2026 8:20:00 AM. 50 Economy ticket for $226 per person are available. Travel duration is 11h 20m
Fastest Flights Saturday
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Lufthansa1h 0m07:20 AMFrankfurt am Main AirportFrankfurt am Main Airport8:20 AMBrussels AirportBrussels Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 3/22/2026 7:20:00 AM to Brussels Airport, Brussels Airport (Belgium) arriving at 3/22/2026 8:20:00 AM. 50 Economy ticket for $193 per person are available. Travel duration is 1h 0m
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Lufthansa1h 0m09:30 PMFrankfurt am Main AirportFrankfurt am Main Airport10:30 PMBrussels AirportBrussels Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 3/22/2026 9:30:00 PM to Brussels Airport, Brussels Airport (Belgium) arriving at 3/22/2026 10:30:00 PM. 50 Economy ticket for $242 per person are available. Travel duration is 1h 0m
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Brussels Airlines1h 5m011:30 AMFrankfurt am Main AirportFrankfurt am Main Airport12:35 PMBrussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 3/22/2026 11:30:00 AM to Brussels Airport, Brussels Airport (Belgium) arriving at 3/22/2026 12:35:00 PM. 50 Economy ticket for $193 per person are available. Travel duration is 1h 5m
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Brussels Airlines1h 5m04:25 PMFrankfurt am Main AirportFrankfurt am Main Airport5:30 PMBrussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 3/22/2026 4:25:00 PM to Brussels Airport, Brussels Airport (Belgium) arriving at 3/22/2026 5:30:00 PM. 50 Economy ticket for $193 per person are available. Travel duration is 1h 5m
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Deutsche Bahn9h 24m07:20 PMMainzCentral Station4:44 AMBrusselsCentral Station0EconomyA Train from Deutsche Bahn goes from Central Station, Mainz (Germany) at 3/22/2026 7:20:00 PM to Central Station, Brussels (Belgium) arriving at 3/23/2026 4:44:00 AM. 50 Economy ticket for $57 per person are available. Travel duration is 9h 24m
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BlaBlaCar Bus13h 48m012:25 PMFrankfurt am Main AirportFrankfurt am Main Airport2:13 AMBrusselsMidi Bus Station0EconomyA Bus from BlaBlaCar Bus goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 3/22/2026 12:25:00 PM to Midi Bus Station, Brussels (Belgium) arriving at 3/23/2026 2:13:00 AM. 50 Economy ticket for $75 per person are available. Travel duration is 13h 48m
Fastest Flights Sunday
Fastest Trains Sunday
Fastest Buses Sunday
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Brussels Airlines1h 0m09:30 PMFrankfurt am Main AirportFrankfurt am Main Airport10:30 PMBrussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 3/23/2026 9:30:00 PM to Brussels Airport, Brussels Airport (Belgium) arriving at 3/23/2026 10:30:00 PM. 50 Economy ticket for $192 per person are available. Travel duration is 1h 0m
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Lufthansa1h 0m07:20 AMFrankfurt am Main AirportFrankfurt am Main Airport8:20 AMBrussels AirportBrussels Airport0EconomyA Flight from Lufthansa goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 3/23/2026 7:20:00 AM to Brussels Airport, Brussels Airport (Belgium) arriving at 3/23/2026 8:20:00 AM. 50 Economy ticket for $193 per person are available. Travel duration is 1h 0m
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Brussels Airlines1h 5m011:30 AMFrankfurt am Main AirportFrankfurt am Main Airport12:35 PMBrussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 3/23/2026 11:30:00 AM to Brussels Airport, Brussels Airport (Belgium) arriving at 3/23/2026 12:35:00 PM. 50 Economy ticket for $192 per person are available. Travel duration is 1h 5m
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Brussels Airlines1h 5m012:30 PMFrankfurt am Main AirportFrankfurt am Main Airport1:35 PMBrussels AirportBrussels Airport0EconomyA Flight from Brussels Airlines goes from Frankfurt am Main Airport, Frankfurt am Main Airport (Germany) at 3/23/2026 12:30:00 PM to Brussels Airport, Brussels Airport (Belgium) arriving at 3/23/2026 1:35:00 PM. 50 Economy ticket for $192 per person are available. Travel duration is 1h 5m
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Deutsche Bahn2h 56m06:48 PMFrankfurt am Main AirportFrankfurt am Main Airport Train Station9:44 PMBrusselsCentral Station0EconomyA Train from Deutsche Bahn goes from Frankfurt am Main Airport Train Station, Frankfurt am Main Airport (Germany) at 3/23/2026 6:48:00 PM to Central Station, Brussels (Belgium) arriving at 3/23/2026 9:44:00 PM. 50 Economy ticket for $48 per person are available. Travel duration is 2h 56m
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Deutsche Bahn2h 56m06:48 AMFrankfurt am Main AirportFrankfurt am Main Airport Train Station9:44 AMBrusselsCentral Station0EconomyA Train from Deutsche Bahn goes from Frankfurt am Main Airport Train Station, Frankfurt am Main Airport (Germany) at 3/23/2026 6:48:00 AM to Central Station, Brussels (Belgium) arriving at 3/23/2026 9:44:00 AM. 50 Economy ticket for $62 per person are available. Travel duration is 2h 56m
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Deutsche Bahn3h 27m06:48 PMFrankfurt am Main AirportFrankfurt am Main Airport Train Station10:15 PMBrusselsCentral Station0EconomyA Train from Deutsche Bahn goes from Frankfurt am Main Airport Train Station, Frankfurt am Main Airport (Germany) at 3/23/2026 6:48:00 PM to Central Station, Brussels (Belgium) arriving at 3/23/2026 10:15:00 PM. 50 Economy ticket for $48 per person are available. Travel duration is 3h 27m
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Deutsche Bahn3h 46m08:29 PMFrankfurt am Main AirportFrankfurt am Main Airport Train Station12:15 AMBrusselsCentral Station0EconomyA Train from Deutsche Bahn goes from Frankfurt am Main Airport Train Station, Frankfurt am Main Airport (Germany) at 3/23/2026 8:29:00 PM to Central Station, Brussels (Belgium) arriving at 3/24/2026 12:15:00 AM. 50 Economy ticket for $39 per person are available. Travel duration is 3h 46m
Fastest Flights Monday
Fastest Trains Monday
Here you will find all operators and timetables for a
Bus from Mainz to Brussels
What are the most popular stations in Mainz and Brussels?
In Mainz, you will usually depart from Laubenheim Train Station, Central Bus Station or Central Station, while in Brussels you will be arriving at Midi Bus Station, North Station or Gare Centrale, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Brussels from Mainz? With 8 connections between 1 Flight, Train and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Mainz and Brussels, you can pay as low as $39 with a Train from Deutsche Bahn.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Lufthansa: you will get to Brussels in just 1h 0m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Mainz and Brussels are Lufthansa, Brussels Airlines and Deutsche Bahn, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Mainz and Brussels is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Budenheim or to Saint-Gilles, and look at flights from Frankfurt am Main Airport, and landing at Brussels South Charleroi Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Mainz to Brussels?
The most popular companies between Mainz and Brussels, are Lufthansa, Brussels Airlines and Deutsche Bahn. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: BlaBlaCar Bus
Train companies: Deutsche Bahn
Airlines: Lufthansa, Brussels Airlines, EasyJet Airline and 5 more.
All you need to know when you travel from Mainz to Brussels
Check all information on comfort and services on all modes of transports from Mainz to Brussels. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Mainz to Brussels
How can I reach Brussels from Mainz?
Every day, there are on average 8 connections between Flight, Train and Bus, with which you can get to Brussels from Mainz.
How far is Brussels from Mainz?
The distance between Mainz and Brussels is 181.5 miles.
What is the most ecofriendly mode of transport between Mainz and Brussels?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 8 kgs of CO2, a train 10 kgs, a car 50 kgs, and a flight 72 kgs.
What is the cheapest mode of transport from Mainz to Brussels?
You can get to Brussels with just $39 by taking a Train from Deutsche Bahn.
What is the fastest way to get from Mainz to Brussels?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Brussels in just 1h 0m with a Flight from Lufthansa.
More routes to Mainz and to Brussels
Looking for more options? Here you can see the most popular routes to Mainz and to Brussels. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Mainz
- Berlin to Mainz
- Bremen to Mainz
- Dresden to Mainz
- Frankfurt am Main Airport to Mainz
- Frankfurt Hahn Airport to Mainz
- Freiburg to Mainz
- Kaiserslautern to Mainz
- Koblenz to Mainz
- Munich to Mainz
- Saarbruecken to Mainz
- Simmern (Hunsrück) to Mainz
- Trips to Brussels
- Amsterdam to Brussels
- Antwerp to Brussels
- Barcelona to Brussels
- Basel to Brussels
- Berlin to Brussels
- Birmingham to Brussels
- Bordeaux to Brussels
- Bratislava to Brussels
- Brussels South Charleroi Airport to Brussels
- Cologne/Bonn Airport to Brussels
- Lisbon to Brussels
- London to Brussels
- Lyon to Brussels
- Madrid to Brussels
- Milan to Brussels
- Newcastle upon Tyne to Brussels
- Nottingham to Brussels
- Paris to Brussels
- Prague to Brussels
- Salzburg to Brussels
- The Hague to Brussels
- Toulouse to Brussels
- Vienna to Brussels
- Zurich to Brussels
