What is the best way to travel from Myrtle Beach, SC to Columbus, OH?
Looking for a trip? Compare all the available Buses and Flights for the journey to Columbus, OH from Myrtle Beach, SC. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 1 available companies to find your perfect trip!
What is the cheapest way to reach Columbus, OH from Myrtle Beach, SC?
You can get to Columbus, OH with just $124 by taking a Bus from Greyhound US, but you can find many more cheap offers: we have selected the best ones for next few days here for you.
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Greyhound US29h 55m01:55 PMMyrtle Beach, SCBus Stop7:50 PMColumbus, OHABM Public Parking0EconomyA Bus from Greyhound US goes from Bus Stop, Myrtle Beach, SC (USA) at 12/5/2025 1:55:00 PM to ABM Public Parking, Columbus, OH (USA) arriving at 12/6/2025 7:50:00 PM. 50 Economy ticket for $124 per person are available. Travel duration is 29h 55m
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Greyhound US23h 0m01:55 PMMyrtle Beach, SCBus Stop12:55 PMColumbus, OHE Main St & S Lazelle St0EconomyA Bus from Greyhound US goes from Bus Stop, Myrtle Beach, SC (USA) at 12/5/2025 1:55:00 PM to E Main St & S Lazelle St, Columbus, OH (USA) arriving at 12/6/2025 12:55:00 PM. 50 Economy ticket for $124 per person are available. Travel duration is 23h 0m
Cheapest Buses Friday
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Greyhound US29h 55m01:55 PMMyrtle Beach, SCBus Stop7:50 PMColumbus, OHABM Public Parking0EconomyA Bus from Greyhound US goes from Bus Stop, Myrtle Beach, SC (USA) at 12/8/2025 1:55:00 PM to ABM Public Parking, Columbus, OH (USA) arriving at 12/9/2025 7:50:00 PM. 50 Economy ticket for $124 per person are available. Travel duration is 29h 55m
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Greyhound US23h 0m01:55 PMMyrtle Beach, SCBus Stop12:55 PMColumbus, OHE Main St & S Lazelle St0EconomyA Bus from Greyhound US goes from Bus Stop, Myrtle Beach, SC (USA) at 12/8/2025 1:55:00 PM to E Main St & S Lazelle St, Columbus, OH (USA) arriving at 12/9/2025 12:55:00 PM. 50 Economy ticket for $125 per person are available. Travel duration is 23h 0m
Cheapest Buses Monday
What are the fastest trips from Myrtle Beach, SC to Columbus, OH?
You can get to Columbus, OH from Myrtle Beach, SC in just 23h 0m with a Bus from Greyhound US. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.
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Greyhound US23h 0m01:55 PMMyrtle Beach, SCBus Stop12:55 PMColumbus, OHE Main St & S Lazelle St0EconomyA Bus from Greyhound US goes from Bus Stop, Myrtle Beach, SC (USA) at 12/5/2025 1:55:00 PM to E Main St & S Lazelle St, Columbus, OH (USA) arriving at 12/6/2025 12:55:00 PM. 50 Economy ticket for $124 per person are available. Travel duration is 23h 0m
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Greyhound US29h 55m01:55 PMMyrtle Beach, SCBus Stop7:50 PMColumbus, OHABM Public Parking0EconomyA Bus from Greyhound US goes from Bus Stop, Myrtle Beach, SC (USA) at 12/5/2025 1:55:00 PM to ABM Public Parking, Columbus, OH (USA) arriving at 12/6/2025 7:50:00 PM. 50 Economy ticket for $124 per person are available. Travel duration is 29h 55m
Fastest Buses Friday
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Greyhound US23h 0m01:55 PMMyrtle Beach, SCBus Stop12:55 PMColumbus, OHE Main St & S Lazelle St0EconomyA Bus from Greyhound US goes from Bus Stop, Myrtle Beach, SC (USA) at 12/8/2025 1:55:00 PM to E Main St & S Lazelle St, Columbus, OH (USA) arriving at 12/9/2025 12:55:00 PM. 50 Economy ticket for $125 per person are available. Travel duration is 23h 0m
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Greyhound US29h 55m01:55 PMMyrtle Beach, SCBus Stop7:50 PMColumbus, OHABM Public Parking0EconomyA Bus from Greyhound US goes from Bus Stop, Myrtle Beach, SC (USA) at 12/8/2025 1:55:00 PM to ABM Public Parking, Columbus, OH (USA) arriving at 12/9/2025 7:50:00 PM. 50 Economy ticket for $124 per person are available. Travel duration is 29h 55m
Fastest Buses Monday
Here you will find all operators and timetables for a
Bus from Myrtle Beach, SC to Columbus, OH
What are the most popular stations in Myrtle Beach, SC and Columbus, OH?
In Myrtle Beach, SC, you will usually depart from Bus Stop, while in Columbus, OH you will be arriving at E Main St & S Lazelle St, ABM Public Parking or Greyhound Bus Station, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Columbus, OH from Myrtle Beach, SC? With 2 connections between 1 Bus and Flight operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Myrtle Beach, SC and Columbus, OH, you can pay as low as $124 with a Bus from Greyhound US.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Bus from Greyhound US: you will get to Columbus, OH in just 23h 0m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Myrtle Beach, SC and Columbus, OH are Greyhound US, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Myrtle Beach, SC and Columbus, OH is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Forestbrook, SC or to Upper Arlington, OH, and look at flights from , and landing at Columbus Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Myrtle Beach, SC to Columbus, OH?
The most popular companies between Myrtle Beach, SC and Columbus, OH, are Greyhound US. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: Greyhound US
All you need to know when you travel from Myrtle Beach, SC to Columbus, OH
Check all information on comfort and services on all modes of transports from Myrtle Beach, SC to Columbus, OH. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Myrtle Beach, SC to Columbus, OH
How can I reach Columbus, OH from Myrtle Beach, SC?
Every day, there are on average 2 connections between Bus and Flight, with which you can get to Columbus, OH from Myrtle Beach, SC.
How far is Columbus, OH from Myrtle Beach, SC?
The distance between Myrtle Beach, SC and Columbus, OH is 489.7 miles.
What is the most ecofriendly mode of transport between Myrtle Beach, SC and Columbus, OH?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 21 kgs of CO2, a train 28 kgs, a car 134 kgs, and a flight 194 kgs.
What is the cheapest mode of transport from Myrtle Beach, SC to Columbus, OH?
You can get to Columbus, OH with just $124 by taking a Bus from Greyhound US.
What is the fastest way to get from Myrtle Beach, SC to Columbus, OH?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Columbus, OH in just 23h 0m with a Bus from Greyhound US.
More routes to Myrtle Beach, SC and to Columbus, OH
Looking for more options? Here you can see the most popular routes to Myrtle Beach, SC and to Columbus, OH. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Myrtle Beach, SC
- Atlanta, GA to Myrtle Beach, SC
- New York to Myrtle Beach, SC
- Newark to Myrtle Beach, SC

