What is the best way to travel from Orlando, FL to Myrtle Beach, SC?
Looking for a trip? Compare all the available Buses and Flights for the journey to Myrtle Beach, SC from Orlando, FL. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 2 available companies to find your perfect trip!
What is the cheapest way to reach Myrtle Beach, SC from Orlando, FL?
You can get to Myrtle Beach, SC with just $107 by taking a Bus from FlixBus, but you can find many more cheap offers: we have selected the best ones for next few days here for you.
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Greyhound US18h 40m08:40 PMOrlando, FLBus Station3:20 PMMyrtle Beach, SCBus Stop0EconomyA Bus from Greyhound US goes from Bus Station, Orlando, FL (USA) at 12/8/2025 8:40:00 PM to Bus Stop, Myrtle Beach, SC (USA) arriving at 12/9/2025 3:20:00 PM. 50 Economy ticket for $113 per person are available. Travel duration is 18h 40m
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FlixBus10h 35m04:45 AMOrlando, FLBus Station3:20 PMMyrtle Beach, SCBus Stop0EconomyA Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 12/8/2025 4:45:00 AM to Bus Stop, Myrtle Beach, SC (USA) arriving at 12/8/2025 3:20:00 PM. 50 Economy ticket for $114 per person are available. Travel duration is 10h 35m
Cheapest Buses Monday
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FlixBus11h 5m04:45 AMOrlando, FLBus Station3:50 PMMyrtle Beach, SCBus Stop0EconomyA Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 12/11/2025 4:45:00 AM to Bus Stop, Myrtle Beach, SC (USA) arriving at 12/11/2025 3:50:00 PM. 50 Economy ticket for $107 per person are available. Travel duration is 11h 5m
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Greyhound US19h 10m08:40 PMOrlando, FLBus Station3:50 PMMyrtle Beach, SCBus Stop0EconomyA Bus from Greyhound US goes from Bus Station, Orlando, FL (USA) at 12/11/2025 8:40:00 PM to Bus Stop, Myrtle Beach, SC (USA) arriving at 12/12/2025 3:50:00 PM. 50 Economy ticket for $108 per person are available. Travel duration is 19h 10m
Cheapest Buses Thursday
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FlixBus10h 35m04:45 AMOrlando, FLBus Station3:20 PMMyrtle Beach, SCBus Stop0EconomyA Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 12/13/2025 4:45:00 AM to Bus Stop, Myrtle Beach, SC (USA) arriving at 12/13/2025 3:20:00 PM. 50 Economy ticket for $109 per person are available. Travel duration is 10h 35m
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Greyhound US18h 40m08:40 PMOrlando, FLBus Station3:20 PMMyrtle Beach, SCBus Stop0EconomyA Bus from Greyhound US goes from Bus Station, Orlando, FL (USA) at 12/13/2025 8:40:00 PM to Bus Stop, Myrtle Beach, SC (USA) arriving at 12/14/2025 3:20:00 PM. 50 Economy ticket for $111 per person are available. Travel duration is 18h 40m
Cheapest Buses Saturday
What are the fastest trips from Orlando, FL to Myrtle Beach, SC?
You can get to Myrtle Beach, SC from Orlando, FL in just 10h 35m with a Bus from FlixBus. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.
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FlixBus10h 35m04:45 AMOrlando, FLBus Station3:20 PMMyrtle Beach, SCBus Stop0EconomyA Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 12/8/2025 4:45:00 AM to Bus Stop, Myrtle Beach, SC (USA) arriving at 12/8/2025 3:20:00 PM. 50 Economy ticket for $114 per person are available. Travel duration is 10h 35m
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Greyhound US18h 40m08:40 PMOrlando, FLBus Station3:20 PMMyrtle Beach, SCBus Stop0EconomyA Bus from Greyhound US goes from Bus Station, Orlando, FL (USA) at 12/8/2025 8:40:00 PM to Bus Stop, Myrtle Beach, SC (USA) arriving at 12/9/2025 3:20:00 PM. 50 Economy ticket for $113 per person are available. Travel duration is 18h 40m
Fastest Buses Monday
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FlixBus11h 5m04:45 AMOrlando, FLBus Station3:50 PMMyrtle Beach, SCBus Stop0EconomyA Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 12/11/2025 4:45:00 AM to Bus Stop, Myrtle Beach, SC (USA) arriving at 12/11/2025 3:50:00 PM. 50 Economy ticket for $107 per person are available. Travel duration is 11h 5m
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Greyhound US19h 10m08:40 PMOrlando, FLBus Station3:50 PMMyrtle Beach, SCBus Stop0EconomyA Bus from Greyhound US goes from Bus Station, Orlando, FL (USA) at 12/11/2025 8:40:00 PM to Bus Stop, Myrtle Beach, SC (USA) arriving at 12/12/2025 3:50:00 PM. 50 Economy ticket for $108 per person are available. Travel duration is 19h 10m
Fastest Buses Thursday
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FlixBus10h 35m04:45 AMOrlando, FLBus Station3:20 PMMyrtle Beach, SCBus Stop0EconomyA Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 12/13/2025 4:45:00 AM to Bus Stop, Myrtle Beach, SC (USA) arriving at 12/13/2025 3:20:00 PM. 50 Economy ticket for $109 per person are available. Travel duration is 10h 35m
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Greyhound US18h 40m08:40 PMOrlando, FLBus Station3:20 PMMyrtle Beach, SCBus Stop0EconomyA Bus from Greyhound US goes from Bus Station, Orlando, FL (USA) at 12/13/2025 8:40:00 PM to Bus Stop, Myrtle Beach, SC (USA) arriving at 12/14/2025 3:20:00 PM. 50 Economy ticket for $111 per person are available. Travel duration is 18h 40m
Fastest Buses Saturday
Here you will find all operators and timetables for a
Bus from Orlando, FL to Myrtle Beach, SC
What are the most popular stations in Orlando, FL and Myrtle Beach, SC?
In Orlando, FL, you will usually depart from Bus Station, Dahlia Dr and S Semoran Blvd Bus Stop or Central Station, while in Myrtle Beach, SC you will be arriving at Bus Stop, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Myrtle Beach, SC from Orlando, FL? With 3 connections between 2 Bus and Flight operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Orlando, FL and Myrtle Beach, SC, you can pay as low as $107 with a Bus from FlixBus.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Bus from FlixBus: you will get to Myrtle Beach, SC in just 10h 35m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Orlando, FL and Myrtle Beach, SC are Greyhound US and FlixBus, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Orlando, FL and Myrtle Beach, SC is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Fairview Shores, FL or to Forestbrook, SC, and look at flights from Orlando Airport, and landing at . Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Orlando, FL to Myrtle Beach, SC?
The most popular companies between Orlando, FL and Myrtle Beach, SC, are Greyhound US and FlixBus. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: Greyhound US and FlixBus
All you need to know when you travel from Orlando, FL to Myrtle Beach, SC
Check all information on comfort and services on all modes of transports from Orlando, FL to Myrtle Beach, SC. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Orlando, FL to Myrtle Beach, SC
How can I reach Myrtle Beach, SC from Orlando, FL?
Every day, there are on average 3 connections between Bus and Flight, with which you can get to Myrtle Beach, SC from Orlando, FL.
How far is Myrtle Beach, SC from Orlando, FL?
The distance between Orlando, FL and Myrtle Beach, SC is 385.1 miles.
What is the most ecofriendly mode of transport between Orlando, FL and Myrtle Beach, SC?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 17 kgs of CO2, a train 22 kgs, a car 105 kgs, and a flight 152 kgs.
What is the cheapest mode of transport from Orlando, FL to Myrtle Beach, SC?
You can get to Myrtle Beach, SC with just $107 by taking a Bus from FlixBus.
What is the fastest way to get from Orlando, FL to Myrtle Beach, SC?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Myrtle Beach, SC in just 10h 35m with a Bus from FlixBus.
More routes to Orlando, FL and to Myrtle Beach, SC
Looking for more options? Here you can see the most popular routes to Orlando, FL and to Myrtle Beach, SC. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Orlando, FL
- Atlanta, GA to Orlando, FL
- Baltimore, MD to Orlando, FL
- Boston, MA to Orlando, FL
- Charlotte to Orlando, FL
- Chicago to Orlando, FL
- Columbus, OH to Orlando, FL
- Dallas to Orlando, FL
- El Paso, TX to Orlando, FL
- Fort Lauderdale Airport to Orlando, FL
- Fort Lauderdale, FL to Orlando, FL
- Houston to Orlando, FL
- Miami Airport to Orlando, FL
- Miami Beach, FL to Orlando, FL
- Miami to Orlando, FL
- Monterrey, NL to Orlando, FL
- New York to Orlando, FL
- Newark to Orlando, FL
- Philadelphia to Orlando, FL
- Providence, RI to Orlando, FL
- Syracuse, NY to Orlando, FL
- Trips to Myrtle Beach, SC
- Atlanta, GA to Myrtle Beach, SC
- New York to Myrtle Beach, SC
- Newark to Myrtle Beach, SC

