What is the best way to travel from Orlando, FL to Myrtle Beach, SC?
Looking for a trip? Compare all the available Flights and Buses for the journey to Myrtle Beach, SC from Orlando, FL. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 1 available companies to find your perfect trip!
What is the cheapest way to reach Myrtle Beach, SC from Orlando, FL?
You can get to Myrtle Beach, SC with just $71 by taking a Bus from FlixBus, but you can find many more cheap offers: we have selected the best ones for next few days here for you.
-
FlixBus17h 55m09:55 PMOrlando, FLBus Station3:50 PMMyrtle Beach, SCBus Stop0EconomyA Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 11/5/2026 9:55:00 PM to Bus Stop, Myrtle Beach, SC (USA) arriving at 11/6/2026 3:50:00 PM. 50 Economy ticket for $73 per person are available. Travel duration is 17h 55m
-
FlixBus21h 0m02:30 PMOrlando, FLBus Station11:30 AMMyrtle Beach, SCBus Stop0EconomyA Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 11/5/2026 2:30:00 PM to Bus Stop, Myrtle Beach, SC (USA) arriving at 11/6/2026 11:30:00 AM. 50 Economy ticket for $74 per person are available. Travel duration is 21h 0m
Cheapest Buses Thursday
-
FlixBus10h 55m06:00 AMOrlando, FLBus Station4:55 PMMyrtle Beach, SCBus Stop0EconomyA Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 11/6/2026 6:00:00 AM to Bus Stop, Myrtle Beach, SC (USA) arriving at 11/6/2026 4:55:00 PM. 50 Economy ticket for $71 per person are available. Travel duration is 10h 55m
-
FlixBus17h 55m09:55 PMOrlando, FLBus Station3:50 PMMyrtle Beach, SCBus Stop0EconomyA Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 11/6/2026 9:55:00 PM to Bus Stop, Myrtle Beach, SC (USA) arriving at 11/7/2026 3:50:00 PM. 50 Economy ticket for $71 per person are available. Travel duration is 17h 55m
-
FlixBus21h 0m02:30 PMOrlando, FLBus Station11:30 AMMyrtle Beach, SCBus Stop0EconomyA Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 11/6/2026 2:30:00 PM to Bus Stop, Myrtle Beach, SC (USA) arriving at 11/7/2026 11:30:00 AM. 50 Economy ticket for $74 per person are available. Travel duration is 21h 0m
Cheapest Buses Friday
-
FlixBus10h 55m06:00 AMOrlando, FLBus Station4:55 PMMyrtle Beach, SCBus Stop0EconomyA Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 11/7/2026 6:00:00 AM to Bus Stop, Myrtle Beach, SC (USA) arriving at 11/7/2026 4:55:00 PM. 50 Economy ticket for $79 per person are available. Travel duration is 10h 55m
-
FlixBus17h 55m09:55 PMOrlando, FLBus Station3:50 PMMyrtle Beach, SCBus Stop0EconomyA Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 11/7/2026 9:55:00 PM to Bus Stop, Myrtle Beach, SC (USA) arriving at 11/8/2026 3:50:00 PM. 50 Economy ticket for $79 per person are available. Travel duration is 17h 55m
-
FlixBus21h 0m02:30 PMOrlando, FLBus Station11:30 AMMyrtle Beach, SCBus Stop0EconomyA Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 11/7/2026 2:30:00 PM to Bus Stop, Myrtle Beach, SC (USA) arriving at 11/8/2026 11:30:00 AM. 50 Economy ticket for $80 per person are available. Travel duration is 21h 0m
Cheapest Buses Saturday
-
FlixBus10h 55m06:00 AMOrlando, FLBus Station4:55 PMMyrtle Beach, SCBus Stop0EconomyA Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 11/8/2026 6:00:00 AM to Bus Stop, Myrtle Beach, SC (USA) arriving at 11/8/2026 4:55:00 PM. 50 Economy ticket for $81 per person are available. Travel duration is 10h 55m
-
FlixBus17h 55m09:55 PMOrlando, FLBus Station3:50 PMMyrtle Beach, SCBus Stop0EconomyA Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 11/8/2026 9:55:00 PM to Bus Stop, Myrtle Beach, SC (USA) arriving at 11/9/2026 3:50:00 PM. 50 Economy ticket for $81 per person are available. Travel duration is 17h 55m
-
FlixBus21h 0m02:30 PMOrlando, FLBus Station11:30 AMMyrtle Beach, SCBus Stop0EconomyA Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 11/8/2026 2:30:00 PM to Bus Stop, Myrtle Beach, SC (USA) arriving at 11/9/2026 11:30:00 AM. 50 Economy ticket for $84 per person are available. Travel duration is 21h 0m
-
FlixBus25h 20m010:55 PMOrlando, FLBus Station12:15 AMMyrtle Beach, SCBus Stop0EconomyA Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 11/8/2026 10:55:00 PM to Bus Stop, Myrtle Beach, SC (USA) arriving at 11/10/2026 12:15:00 AM. 50 Economy ticket for $87 per person are available. Travel duration is 25h 20m
-
FlixBus19h 0m08:50 PMOrlando, FLBus Station3:50 PMMyrtle Beach, SCBus Stop0EconomyA Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 11/8/2026 8:50:00 PM to Bus Stop, Myrtle Beach, SC (USA) arriving at 11/9/2026 3:50:00 PM. 50 Economy ticket for $88 per person are available. Travel duration is 19h 0m
Cheapest Buses Sunday
-
FlixBus10h 55m06:00 AMOrlando, FLBus Station4:55 PMMyrtle Beach, SCBus Stop0EconomyA Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 11/9/2026 6:00:00 AM to Bus Stop, Myrtle Beach, SC (USA) arriving at 11/9/2026 4:55:00 PM. 50 Economy ticket for $79 per person are available. Travel duration is 10h 55m
-
FlixBus17h 55m09:55 PMOrlando, FLBus Station3:50 PMMyrtle Beach, SCBus Stop0EconomyA Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 11/9/2026 9:55:00 PM to Bus Stop, Myrtle Beach, SC (USA) arriving at 11/10/2026 3:50:00 PM. 50 Economy ticket for $79 per person are available. Travel duration is 17h 55m
-
FlixBus21h 0m02:30 PMOrlando, FLBus Station11:30 AMMyrtle Beach, SCBus Stop0EconomyA Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 11/9/2026 2:30:00 PM to Bus Stop, Myrtle Beach, SC (USA) arriving at 11/10/2026 11:30:00 AM. 50 Economy ticket for $80 per person are available. Travel duration is 21h 0m
Cheapest Buses Monday
What are the fastest trips from Orlando, FL to Myrtle Beach, SC?
You can get to Myrtle Beach, SC from Orlando, FL in just 10h 55m with a Bus from FlixBus. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.
-
FlixBus17h 55m09:55 PMOrlando, FLBus Station3:50 PMMyrtle Beach, SCBus Stop0EconomyA Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 11/5/2026 9:55:00 PM to Bus Stop, Myrtle Beach, SC (USA) arriving at 11/6/2026 3:50:00 PM. 50 Economy ticket for $73 per person are available. Travel duration is 17h 55m
-
FlixBus21h 0m02:30 PMOrlando, FLBus Station11:30 AMMyrtle Beach, SCBus Stop0EconomyA Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 11/5/2026 2:30:00 PM to Bus Stop, Myrtle Beach, SC (USA) arriving at 11/6/2026 11:30:00 AM. 50 Economy ticket for $74 per person are available. Travel duration is 21h 0m
Fastest Buses Thursday
-
FlixBus10h 55m06:00 AMOrlando, FLBus Station4:55 PMMyrtle Beach, SCBus Stop0EconomyA Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 11/6/2026 6:00:00 AM to Bus Stop, Myrtle Beach, SC (USA) arriving at 11/6/2026 4:55:00 PM. 50 Economy ticket for $71 per person are available. Travel duration is 10h 55m
-
FlixBus17h 55m09:55 PMOrlando, FLBus Station3:50 PMMyrtle Beach, SCBus Stop0EconomyA Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 11/6/2026 9:55:00 PM to Bus Stop, Myrtle Beach, SC (USA) arriving at 11/7/2026 3:50:00 PM. 50 Economy ticket for $71 per person are available. Travel duration is 17h 55m
-
FlixBus21h 0m02:30 PMOrlando, FLBus Station11:30 AMMyrtle Beach, SCBus Stop0EconomyA Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 11/6/2026 2:30:00 PM to Bus Stop, Myrtle Beach, SC (USA) arriving at 11/7/2026 11:30:00 AM. 50 Economy ticket for $74 per person are available. Travel duration is 21h 0m
Fastest Buses Friday
-
FlixBus10h 55m06:00 AMOrlando, FLBus Station4:55 PMMyrtle Beach, SCBus Stop0EconomyA Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 11/7/2026 6:00:00 AM to Bus Stop, Myrtle Beach, SC (USA) arriving at 11/7/2026 4:55:00 PM. 50 Economy ticket for $79 per person are available. Travel duration is 10h 55m
-
FlixBus17h 55m09:55 PMOrlando, FLBus Station3:50 PMMyrtle Beach, SCBus Stop0EconomyA Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 11/7/2026 9:55:00 PM to Bus Stop, Myrtle Beach, SC (USA) arriving at 11/8/2026 3:50:00 PM. 50 Economy ticket for $79 per person are available. Travel duration is 17h 55m
-
FlixBus21h 0m02:30 PMOrlando, FLBus Station11:30 AMMyrtle Beach, SCBus Stop0EconomyA Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 11/7/2026 2:30:00 PM to Bus Stop, Myrtle Beach, SC (USA) arriving at 11/8/2026 11:30:00 AM. 50 Economy ticket for $80 per person are available. Travel duration is 21h 0m
Fastest Buses Saturday
-
FlixBus10h 55m06:00 AMOrlando, FLBus Station4:55 PMMyrtle Beach, SCBus Stop0EconomyA Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 11/8/2026 6:00:00 AM to Bus Stop, Myrtle Beach, SC (USA) arriving at 11/8/2026 4:55:00 PM. 50 Economy ticket for $81 per person are available. Travel duration is 10h 55m
-
FlixBus17h 55m09:55 PMOrlando, FLBus Station3:50 PMMyrtle Beach, SCBus Stop0EconomyA Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 11/8/2026 9:55:00 PM to Bus Stop, Myrtle Beach, SC (USA) arriving at 11/9/2026 3:50:00 PM. 50 Economy ticket for $81 per person are available. Travel duration is 17h 55m
-
FlixBus19h 0m08:50 PMOrlando, FLBus Station3:50 PMMyrtle Beach, SCBus Stop0EconomyA Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 11/8/2026 8:50:00 PM to Bus Stop, Myrtle Beach, SC (USA) arriving at 11/9/2026 3:50:00 PM. 50 Economy ticket for $88 per person are available. Travel duration is 19h 0m
-
FlixBus21h 0m02:30 PMOrlando, FLBus Station11:30 AMMyrtle Beach, SCBus Stop0EconomyA Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 11/8/2026 2:30:00 PM to Bus Stop, Myrtle Beach, SC (USA) arriving at 11/9/2026 11:30:00 AM. 50 Economy ticket for $84 per person are available. Travel duration is 21h 0m
-
FlixBus25h 20m010:55 PMOrlando, FLBus Station12:15 AMMyrtle Beach, SCBus Stop0EconomyA Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 11/8/2026 10:55:00 PM to Bus Stop, Myrtle Beach, SC (USA) arriving at 11/10/2026 12:15:00 AM. 50 Economy ticket for $87 per person are available. Travel duration is 25h 20m
Fastest Buses Sunday
-
FlixBus10h 55m06:00 AMOrlando, FLBus Station4:55 PMMyrtle Beach, SCBus Stop0EconomyA Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 11/9/2026 6:00:00 AM to Bus Stop, Myrtle Beach, SC (USA) arriving at 11/9/2026 4:55:00 PM. 50 Economy ticket for $79 per person are available. Travel duration is 10h 55m
-
FlixBus17h 55m09:55 PMOrlando, FLBus Station3:50 PMMyrtle Beach, SCBus Stop0EconomyA Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 11/9/2026 9:55:00 PM to Bus Stop, Myrtle Beach, SC (USA) arriving at 11/10/2026 3:50:00 PM. 50 Economy ticket for $79 per person are available. Travel duration is 17h 55m
-
FlixBus21h 0m02:30 PMOrlando, FLBus Station11:30 AMMyrtle Beach, SCBus Stop0EconomyA Bus from FlixBus goes from Bus Station, Orlando, FL (USA) at 11/9/2026 2:30:00 PM to Bus Stop, Myrtle Beach, SC (USA) arriving at 11/10/2026 11:30:00 AM. 50 Economy ticket for $80 per person are available. Travel duration is 21h 0m
Fastest Buses Monday
Here you will find all operators and timetables for a
Bus from Orlando, FL to Myrtle Beach, SC
What are the most popular stations in Orlando, FL and Myrtle Beach, SC?
In Orlando, FL, you will usually depart from Bus Station, Dahlia Dr and S Semoran Blvd Bus Stop or Central Station, while in Myrtle Beach, SC you will be arriving at Bus Stop, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Myrtle Beach, SC from Orlando, FL? With 3 connections between 1 Flight and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Orlando, FL and Myrtle Beach, SC, you can pay as low as $71 with a Bus from FlixBus.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Bus from FlixBus: you will get to Myrtle Beach, SC in just 10h 55m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Orlando, FL and Myrtle Beach, SC are FlixBus, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Orlando, FL and Myrtle Beach, SC is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Fairview Shores, FL or to Myrtle Beach Airport, and look at flights from Orlando Airport, and landing at Myrtle Beach Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Orlando, FL to Myrtle Beach, SC?
The most popular companies between Orlando, FL and Myrtle Beach, SC, are FlixBus. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: FlixBus
All you need to know when you travel from Orlando, FL to Myrtle Beach, SC
Check all information on comfort and services on all modes of transports from Orlando, FL to Myrtle Beach, SC. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Orlando, FL to Myrtle Beach, SC
How can I reach Myrtle Beach, SC from Orlando, FL?
Every day, there are on average 3 connections between Flight and Bus, with which you can get to Myrtle Beach, SC from Orlando, FL.
How far is Myrtle Beach, SC from Orlando, FL?
The distance between Orlando, FL and Myrtle Beach, SC is 385.1 miles.
What is the most ecofriendly mode of transport between Orlando, FL and Myrtle Beach, SC?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 17 kgs of CO2, a train 22 kgs, a car 105 kgs, and a flight 152 kgs.
What is the cheapest mode of transport from Orlando, FL to Myrtle Beach, SC?
You can get to Myrtle Beach, SC with just $71 by taking a Bus from FlixBus.
What is the fastest way to get from Orlando, FL to Myrtle Beach, SC?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Myrtle Beach, SC in just 10h 55m with a Bus from FlixBus.
More routes to Orlando, FL and to Myrtle Beach, SC
Looking for more options? Here you can see the most popular routes to Orlando, FL and to Myrtle Beach, SC. Simply click on a connection, and you’ll find all the details about the route!
- Trips to Orlando, FL
- Atlanta, GA to Orlando, FL
- Augusta, GA to Orlando, FL
- Baltimore, MD to Orlando, FL
- Boston, MA to Orlando, FL
- Brownsville, TX to Orlando, FL
- Charlotte to Orlando, FL
- Columbus, OH to Orlando, FL
- Dallas to Orlando, FL
- El Paso, TX to Orlando, FL
- Fort Lauderdale, FL to Orlando, FL
- Indianapolis to Orlando, FL
- Miami Airport to Orlando, FL
- Miami to Orlando, FL
- Monterrey, NL to Orlando, FL
- Myrtle Beach, SC to Orlando, FL
- New Orleans, LA to Orlando, FL
- New York to Orlando, FL
- Philadelphia to Orlando, FL
- San Antonio, TX to Orlando, FL
- Syracuse, NY to Orlando, FL
- Washington, DC to Orlando, FL
