What is the best way to travel from St. Louis, MO to Pittsburgh?
Looking for a trip? Compare all the available Buses and Flights for the journey to Pittsburgh from St. Louis, MO. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 2 available companies to find your perfect trip!
What is the cheapest way to reach Pittsburgh from St. Louis, MO?
You can get to Pittsburgh with just $61 by taking a Bus from Greyhound US, but you can find many more cheap offers: we have selected the best ones for next few days here for you.
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Greyhound US14h 35m08:45 AMSt. Louis, MOGateway Station12:20 AMPittsburghGrant Street Transportation Center0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 12/13/2025 8:45:00 AM to Grant Street Transportation Center, Pittsburgh (USA) arriving at 12/14/2025 12:20:00 AM. 50 Economy ticket for $69 per person are available. Travel duration is 14h 35m
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Greyhound US12h 55m01:55 PMSt. Louis, MOGateway Station3:50 AMPittsburghGrant Street Transportation Center0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 12/13/2025 1:55:00 PM to Grant Street Transportation Center, Pittsburgh (USA) arriving at 12/14/2025 3:50:00 AM. 50 Economy ticket for $73 per person are available. Travel duration is 12h 55m
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FlixBus18h 35m011:30 PMSt. Louis, MOGateway Station7:05 PMPittsburghGrant Street Transportation Center0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 12/13/2025 11:30:00 PM to Grant Street Transportation Center, Pittsburgh (USA) arriving at 12/14/2025 7:05:00 PM. 50 Economy ticket for $118 per person are available. Travel duration is 18h 35m
Cheapest Buses Saturday
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Frontier Airlines12h 34m09:54 AMSt. Louis Lambert AirportSt. Louis Lambert Airport11:28 PMPittsburgh AirportPittsburgh Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 12/14/2025 9:54:00 AM to Pittsburgh Airport, Pittsburgh Airport (USA) arriving at 12/14/2025 11:28:00 PM. 50 Economy ticket for $175 per person are available. Travel duration is 12h 34m
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United Airlines5h 36m06:30 AMSt. Louis Lambert AirportSt. Louis Lambert Airport1:06 PMPittsburgh AirportPittsburgh Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 12/14/2025 6:30:00 AM to Pittsburgh Airport, Pittsburgh Airport (USA) arriving at 12/14/2025 1:06:00 PM. 50 Economy ticket for $320 per person are available. Travel duration is 5h 36m
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Skyscanner4h 32m08:30 AMSt. Louis Lambert AirportSt. Louis Lambert Airport2:02 PMPittsburgh AirportPittsburgh Airport0EconomyA Flight from Skyscanner goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 12/14/2025 8:30:00 AM to Pittsburgh Airport, Pittsburgh Airport (USA) arriving at 12/14/2025 2:02:00 PM. 50 Economy ticket for $320 per person are available. Travel duration is 4h 32m
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Spirit Airlines8h 54m02:47 PMSt. Louis Lambert AirportSt. Louis Lambert Airport12:41 AMPittsburgh AirportPittsburgh Airport0EconomyA Flight from Spirit Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 12/14/2025 2:47:00 PM to Pittsburgh Airport, Pittsburgh Airport (USA) arriving at 12/15/2025 12:41:00 AM. 50 Economy ticket for $359 per person are available. Travel duration is 8h 54m
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Alaska Airlines10h 36m07:00 AMSt. Louis Lambert AirportSt. Louis Lambert Airport6:36 PMPittsburgh AirportPittsburgh Airport0EconomyA Flight from Alaska Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 12/14/2025 7:00:00 AM to Pittsburgh Airport, Pittsburgh Airport (USA) arriving at 12/14/2025 6:36:00 PM. 50 Economy ticket for $607 per person are available. Travel duration is 10h 36m
Cheapest Flights Sunday
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Greyhound US14h 40m02:00 AMSt. Louis, MOGateway Station5:40 PMPittsburghGrant Street Transportation Center0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 12/15/2025 2:00:00 AM to Grant Street Transportation Center, Pittsburgh (USA) arriving at 12/15/2025 5:40:00 PM. 50 Economy ticket for $61 per person are available. Travel duration is 14h 40m
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Greyhound US14h 35m08:45 AMSt. Louis, MOGateway Station12:20 AMPittsburghGrant Street Transportation Center0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 12/15/2025 8:45:00 AM to Grant Street Transportation Center, Pittsburgh (USA) arriving at 12/16/2025 12:20:00 AM. 50 Economy ticket for $61 per person are available. Travel duration is 14h 35m
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Greyhound US12h 55m01:55 PMSt. Louis, MOGateway Station3:50 AMPittsburghGrant Street Transportation Center0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 12/15/2025 1:55:00 PM to Grant Street Transportation Center, Pittsburgh (USA) arriving at 12/16/2025 3:50:00 AM. 50 Economy ticket for $65 per person are available. Travel duration is 12h 55m
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FlixBus24h 40m04:00 PMSt. Louis, MOGateway Station5:40 PMPittsburghGrant Street Transportation Center0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 12/15/2025 4:00:00 PM to Grant Street Transportation Center, Pittsburgh (USA) arriving at 12/16/2025 5:40:00 PM. 50 Economy ticket for $104 per person are available. Travel duration is 24h 40m
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FlixBus18h 35m011:30 PMSt. Louis, MOGateway Station7:05 PMPittsburghGrant Street Transportation Center0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 12/15/2025 11:30:00 PM to Grant Street Transportation Center, Pittsburgh (USA) arriving at 12/16/2025 7:05:00 PM. 50 Economy ticket for $105 per person are available. Travel duration is 18h 35m
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Frontier Airlines29h 16m09:54 AMSt. Louis Lambert AirportSt. Louis Lambert Airport4:10 PMPittsburgh AirportPittsburgh Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 12/15/2025 9:54:00 AM to Pittsburgh Airport, Pittsburgh Airport (USA) arriving at 12/16/2025 4:10:00 PM. 50 Economy ticket for $191 per person are available. Travel duration is 29h 16m
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Frontier Airlines23h 40m03:30 PMSt. Louis Lambert AirportSt. Louis Lambert Airport4:10 PMPittsburgh AirportPittsburgh Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 12/15/2025 3:30:00 PM to Pittsburgh Airport, Pittsburgh Airport (USA) arriving at 12/16/2025 4:10:00 PM. 50 Economy ticket for $191 per person are available. Travel duration is 23h 40m
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United Airlines5h 1m011:50 AMSt. Louis Lambert AirportSt. Louis Lambert Airport5:51 PMPittsburgh AirportPittsburgh Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 12/15/2025 11:50:00 AM to Pittsburgh Airport, Pittsburgh Airport (USA) arriving at 12/15/2025 5:51:00 PM. 50 Economy ticket for $447 per person are available. Travel duration is 5h 1m
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Skyscanner4h 50m05:44 PMSt. Louis Lambert AirportSt. Louis Lambert Airport11:34 PMPittsburgh AirportPittsburgh Airport0EconomyA Flight from Skyscanner goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 12/15/2025 5:44:00 PM to Pittsburgh Airport, Pittsburgh Airport (USA) arriving at 12/15/2025 11:34:00 PM. 50 Economy ticket for $447 per person are available. Travel duration is 4h 50m
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United Airlines7h 15m03:19 PMSt. Louis Lambert AirportSt. Louis Lambert Airport11:34 PMPittsburgh AirportPittsburgh Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 12/15/2025 3:19:00 PM to Pittsburgh Airport, Pittsburgh Airport (USA) arriving at 12/15/2025 11:34:00 PM. 50 Economy ticket for $453 per person are available. Travel duration is 7h 15m
Cheapest Buses Monday
Cheapest Flights Monday
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Spirit Airlines9h 51m011:51 AMSt. Louis Lambert AirportSt. Louis Lambert Airport10:42 PMPittsburgh AirportPittsburgh Airport0EconomyA Flight from Spirit Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 12/18/2025 11:51:00 AM to Pittsburgh Airport, Pittsburgh Airport (USA) arriving at 12/18/2025 10:42:00 PM. 50 Economy ticket for $296 per person are available. Travel duration is 9h 51m
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Skyscanner5h 48m06:30 AMSt. Louis Lambert AirportSt. Louis Lambert Airport1:18 PMPittsburgh AirportPittsburgh Airport0EconomyA Flight from Skyscanner goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 12/18/2025 6:30:00 AM to Pittsburgh Airport, Pittsburgh Airport (USA) arriving at 12/18/2025 1:18:00 PM. 50 Economy ticket for $321 per person are available. Travel duration is 5h 48m
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Skyscanner4h 13m08:05 AMSt. Louis Lambert AirportSt. Louis Lambert Airport1:18 PMPittsburgh AirportPittsburgh Airport0EconomyA Flight from Skyscanner goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 12/18/2025 8:05:00 AM to Pittsburgh Airport, Pittsburgh Airport (USA) arriving at 12/18/2025 1:18:00 PM. 50 Economy ticket for $321 per person are available. Travel duration is 4h 13m
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United Airlines4h 44m011:05 AMSt. Louis Lambert AirportSt. Louis Lambert Airport4:49 PMPittsburgh AirportPittsburgh Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 12/18/2025 11:05:00 AM to Pittsburgh Airport, Pittsburgh Airport (USA) arriving at 12/18/2025 4:49:00 PM. 50 Economy ticket for $427 per person are available. Travel duration is 4h 44m
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Alaska Airlines10h 58m07:00 AMSt. Louis Lambert AirportSt. Louis Lambert Airport6:58 PMPittsburgh AirportPittsburgh Airport0EconomyA Flight from Alaska Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 12/18/2025 7:00:00 AM to Pittsburgh Airport, Pittsburgh Airport (USA) arriving at 12/18/2025 6:58:00 PM. 50 Economy ticket for $609 per person are available. Travel duration is 10h 58m
Cheapest Flights Thursday
What are the fastest trips from St. Louis, MO to Pittsburgh?
You can get to Pittsburgh from St. Louis, MO in just 4h 13m with a Flight from Skyscanner. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.
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Greyhound US12h 55m01:55 PMSt. Louis, MOGateway Station3:50 AMPittsburghGrant Street Transportation Center0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 12/13/2025 1:55:00 PM to Grant Street Transportation Center, Pittsburgh (USA) arriving at 12/14/2025 3:50:00 AM. 50 Economy ticket for $73 per person are available. Travel duration is 12h 55m
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Greyhound US14h 35m08:45 AMSt. Louis, MOGateway Station12:20 AMPittsburghGrant Street Transportation Center0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 12/13/2025 8:45:00 AM to Grant Street Transportation Center, Pittsburgh (USA) arriving at 12/14/2025 12:20:00 AM. 50 Economy ticket for $69 per person are available. Travel duration is 14h 35m
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FlixBus18h 35m011:30 PMSt. Louis, MOGateway Station7:05 PMPittsburghGrant Street Transportation Center0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 12/13/2025 11:30:00 PM to Grant Street Transportation Center, Pittsburgh (USA) arriving at 12/14/2025 7:05:00 PM. 50 Economy ticket for $118 per person are available. Travel duration is 18h 35m
Fastest Buses Saturday
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Skyscanner4h 32m08:30 AMSt. Louis Lambert AirportSt. Louis Lambert Airport2:02 PMPittsburgh AirportPittsburgh Airport0EconomyA Flight from Skyscanner goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 12/14/2025 8:30:00 AM to Pittsburgh Airport, Pittsburgh Airport (USA) arriving at 12/14/2025 2:02:00 PM. 50 Economy ticket for $320 per person are available. Travel duration is 4h 32m
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United Airlines5h 36m06:30 AMSt. Louis Lambert AirportSt. Louis Lambert Airport1:06 PMPittsburgh AirportPittsburgh Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 12/14/2025 6:30:00 AM to Pittsburgh Airport, Pittsburgh Airport (USA) arriving at 12/14/2025 1:06:00 PM. 50 Economy ticket for $320 per person are available. Travel duration is 5h 36m
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Spirit Airlines8h 54m02:47 PMSt. Louis Lambert AirportSt. Louis Lambert Airport12:41 AMPittsburgh AirportPittsburgh Airport0EconomyA Flight from Spirit Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 12/14/2025 2:47:00 PM to Pittsburgh Airport, Pittsburgh Airport (USA) arriving at 12/15/2025 12:41:00 AM. 50 Economy ticket for $359 per person are available. Travel duration is 8h 54m
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Alaska Airlines10h 36m07:00 AMSt. Louis Lambert AirportSt. Louis Lambert Airport6:36 PMPittsburgh AirportPittsburgh Airport0EconomyA Flight from Alaska Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 12/14/2025 7:00:00 AM to Pittsburgh Airport, Pittsburgh Airport (USA) arriving at 12/14/2025 6:36:00 PM. 50 Economy ticket for $607 per person are available. Travel duration is 10h 36m
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Frontier Airlines12h 34m09:54 AMSt. Louis Lambert AirportSt. Louis Lambert Airport11:28 PMPittsburgh AirportPittsburgh Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 12/14/2025 9:54:00 AM to Pittsburgh Airport, Pittsburgh Airport (USA) arriving at 12/14/2025 11:28:00 PM. 50 Economy ticket for $175 per person are available. Travel duration is 12h 34m
Fastest Flights Sunday
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Skyscanner4h 50m05:44 PMSt. Louis Lambert AirportSt. Louis Lambert Airport11:34 PMPittsburgh AirportPittsburgh Airport0EconomyA Flight from Skyscanner goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 12/15/2025 5:44:00 PM to Pittsburgh Airport, Pittsburgh Airport (USA) arriving at 12/15/2025 11:34:00 PM. 50 Economy ticket for $447 per person are available. Travel duration is 4h 50m
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United Airlines5h 1m011:50 AMSt. Louis Lambert AirportSt. Louis Lambert Airport5:51 PMPittsburgh AirportPittsburgh Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 12/15/2025 11:50:00 AM to Pittsburgh Airport, Pittsburgh Airport (USA) arriving at 12/15/2025 5:51:00 PM. 50 Economy ticket for $447 per person are available. Travel duration is 5h 1m
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United Airlines7h 15m03:19 PMSt. Louis Lambert AirportSt. Louis Lambert Airport11:34 PMPittsburgh AirportPittsburgh Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 12/15/2025 3:19:00 PM to Pittsburgh Airport, Pittsburgh Airport (USA) arriving at 12/15/2025 11:34:00 PM. 50 Economy ticket for $453 per person are available. Travel duration is 7h 15m
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Frontier Airlines23h 40m03:30 PMSt. Louis Lambert AirportSt. Louis Lambert Airport4:10 PMPittsburgh AirportPittsburgh Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 12/15/2025 3:30:00 PM to Pittsburgh Airport, Pittsburgh Airport (USA) arriving at 12/16/2025 4:10:00 PM. 50 Economy ticket for $191 per person are available. Travel duration is 23h 40m
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Frontier Airlines29h 16m09:54 AMSt. Louis Lambert AirportSt. Louis Lambert Airport4:10 PMPittsburgh AirportPittsburgh Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 12/15/2025 9:54:00 AM to Pittsburgh Airport, Pittsburgh Airport (USA) arriving at 12/16/2025 4:10:00 PM. 50 Economy ticket for $191 per person are available. Travel duration is 29h 16m
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Greyhound US12h 55m01:55 PMSt. Louis, MOGateway Station3:50 AMPittsburghGrant Street Transportation Center0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 12/15/2025 1:55:00 PM to Grant Street Transportation Center, Pittsburgh (USA) arriving at 12/16/2025 3:50:00 AM. 50 Economy ticket for $65 per person are available. Travel duration is 12h 55m
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Greyhound US14h 35m08:45 AMSt. Louis, MOGateway Station12:20 AMPittsburghGrant Street Transportation Center0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 12/15/2025 8:45:00 AM to Grant Street Transportation Center, Pittsburgh (USA) arriving at 12/16/2025 12:20:00 AM. 50 Economy ticket for $61 per person are available. Travel duration is 14h 35m
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Greyhound US14h 40m02:00 AMSt. Louis, MOGateway Station5:40 PMPittsburghGrant Street Transportation Center0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 12/15/2025 2:00:00 AM to Grant Street Transportation Center, Pittsburgh (USA) arriving at 12/15/2025 5:40:00 PM. 50 Economy ticket for $61 per person are available. Travel duration is 14h 40m
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FlixBus18h 35m011:30 PMSt. Louis, MOGateway Station7:05 PMPittsburghGrant Street Transportation Center0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 12/15/2025 11:30:00 PM to Grant Street Transportation Center, Pittsburgh (USA) arriving at 12/16/2025 7:05:00 PM. 50 Economy ticket for $105 per person are available. Travel duration is 18h 35m
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FlixBus24h 40m04:00 PMSt. Louis, MOGateway Station5:40 PMPittsburghGrant Street Transportation Center0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 12/15/2025 4:00:00 PM to Grant Street Transportation Center, Pittsburgh (USA) arriving at 12/16/2025 5:40:00 PM. 50 Economy ticket for $104 per person are available. Travel duration is 24h 40m
Fastest Flights Monday
Fastest Buses Monday
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Skyscanner4h 13m08:05 AMSt. Louis Lambert AirportSt. Louis Lambert Airport1:18 PMPittsburgh AirportPittsburgh Airport0EconomyA Flight from Skyscanner goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 12/18/2025 8:05:00 AM to Pittsburgh Airport, Pittsburgh Airport (USA) arriving at 12/18/2025 1:18:00 PM. 50 Economy ticket for $321 per person are available. Travel duration is 4h 13m
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United Airlines4h 44m011:05 AMSt. Louis Lambert AirportSt. Louis Lambert Airport4:49 PMPittsburgh AirportPittsburgh Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 12/18/2025 11:05:00 AM to Pittsburgh Airport, Pittsburgh Airport (USA) arriving at 12/18/2025 4:49:00 PM. 50 Economy ticket for $427 per person are available. Travel duration is 4h 44m
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Skyscanner5h 48m06:30 AMSt. Louis Lambert AirportSt. Louis Lambert Airport1:18 PMPittsburgh AirportPittsburgh Airport0EconomyA Flight from Skyscanner goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 12/18/2025 6:30:00 AM to Pittsburgh Airport, Pittsburgh Airport (USA) arriving at 12/18/2025 1:18:00 PM. 50 Economy ticket for $321 per person are available. Travel duration is 5h 48m
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Spirit Airlines9h 51m011:51 AMSt. Louis Lambert AirportSt. Louis Lambert Airport10:42 PMPittsburgh AirportPittsburgh Airport0EconomyA Flight from Spirit Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 12/18/2025 11:51:00 AM to Pittsburgh Airport, Pittsburgh Airport (USA) arriving at 12/18/2025 10:42:00 PM. 50 Economy ticket for $296 per person are available. Travel duration is 9h 51m
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Alaska Airlines10h 58m07:00 AMSt. Louis Lambert AirportSt. Louis Lambert Airport6:58 PMPittsburgh AirportPittsburgh Airport0EconomyA Flight from Alaska Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 12/18/2025 7:00:00 AM to Pittsburgh Airport, Pittsburgh Airport (USA) arriving at 12/18/2025 6:58:00 PM. 50 Economy ticket for $609 per person are available. Travel duration is 10h 58m
Fastest Flights Thursday
Here you will find all operators and timetables for a
Bus from St. Louis, MO to Pittsburgh
What are the most popular stations in St. Louis, MO and Pittsburgh?
In St. Louis, MO, you will usually depart from Gateway Station, Lindbergh @ Hackberry NB Bus Stop or Skinker Boulevard, while in Pittsburgh you will be arriving at Grant Street Transportation Center, David L. Lawrence Convention Center or Central Station, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Pittsburgh from St. Louis, MO? With 5 connections between 2 Bus and Flight operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between St. Louis, MO and Pittsburgh, you can pay as low as $61 with a Bus from Greyhound US.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Skyscanner: you will get to Pittsburgh in just 4h 13m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting St. Louis, MO and Pittsburgh are Greyhound US, United Airlines and Skyscanner, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in St. Louis, MO and Pittsburgh is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Sauget, IL or to Green Tree, PA, and look at flights from St. Louis Lambert Airport, and landing at Pittsburgh Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from St. Louis, MO to Pittsburgh?
The most popular companies between St. Louis, MO and Pittsburgh, are Greyhound US, United Airlines and Skyscanner. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: Greyhound US and FlixBus
Airlines: United Airlines, Skyscanner, Frontier Airlines and 2 more.
All you need to know when you travel from St. Louis, MO to Pittsburgh
Check all information on comfort and services on all modes of transports from St. Louis, MO to Pittsburgh. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from St. Louis, MO to Pittsburgh
How can I reach Pittsburgh from St. Louis, MO?
Every day, there are on average 5 connections between Bus and Flight, with which you can get to Pittsburgh from St. Louis, MO.
How far is Pittsburgh from St. Louis, MO?
The distance between St. Louis, MO and Pittsburgh is 558.2 miles.
What is the most ecofriendly mode of transport between St. Louis, MO and Pittsburgh?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 24 kgs of CO2, a train 31 kgs, a car 153 kgs, and a flight 221 kgs.
What is the cheapest mode of transport from St. Louis, MO to Pittsburgh?
You can get to Pittsburgh with just $61 by taking a Bus from Greyhound US.
What is the fastest way to get from St. Louis, MO to Pittsburgh?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Pittsburgh in just 4h 13m with a Flight from Skyscanner.
More routes to St. Louis, MO and to Pittsburgh
Looking for more options? Here you can see the most popular routes to St. Louis, MO and to Pittsburgh. Simply click on a connection, and you’ll find all the details about the route!

