Bus Charleston, SC to Philadelphia - Compare all Companies

Compare all timetables for the bus from Charleston, SC to Philadelphia

Here is a selection of the cheapest bus trips from the schedule from Charleston, SC to Philadelphia from various bus operators like Greyhound US for the next days.

today

$101

tomorrow

$124

Friday

$153

Saturday

$188

Sunday

Monday

Tuesday

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	27h 15m	11:15 AM	Charleston, SC	Bus Station	2:30 PM	Philadelphia	IRS Building	Economy	$101	A Bus from Greyhound US goes from Bus Station, Charleston, SC (USA) at 12/17/2025 11:15:00 AM to IRS Building, Philadelphia (USA) arriving at 12/18/2025 2:30:00 PM. 50 Economy ticket for $101 per person are available. Travel duration is 27h 15m
Greyhound US	19h 30m	11:15 AM	Charleston, SC	Bus Station	6:45 AM	Philadelphia	Spring Garden St Station	Economy	$101	A Bus from Greyhound US goes from Bus Station, Charleston, SC (USA) at 12/17/2025 11:15:00 AM to Spring Garden St Station, Philadelphia (USA) arriving at 12/18/2025 6:45:00 AM. 50 Economy ticket for $101 per person are available. Travel duration is 19h 30m
Greyhound US	21h 30m	11:15 AM	Charleston, SC	Bus Station	8:45 AM	Philadelphia	Spring Garden St Station	Economy	$101	A Bus from Greyhound US goes from Bus Station, Charleston, SC (USA) at 12/17/2025 11:15:00 AM to Spring Garden St Station, Philadelphia (USA) arriving at 12/18/2025 8:45:00 AM. 50 Economy ticket for $101 per person are available. Travel duration is 21h 30m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	19h 30m	11:15 AM	Charleston, SC	Bus Station	6:45 AM	Philadelphia	Spring Garden St Station	Economy	$124	A Bus from Greyhound US goes from Bus Station, Charleston, SC (USA) at 12/18/2025 11:15:00 AM to Spring Garden St Station, Philadelphia (USA) arriving at 12/19/2025 6:45:00 AM. 50 Economy ticket for $124 per person are available. Travel duration is 19h 30m
Greyhound US	21h 30m	11:15 AM	Charleston, SC	Bus Station	8:45 AM	Philadelphia	Spring Garden St Station	Economy	$125	A Bus from Greyhound US goes from Bus Station, Charleston, SC (USA) at 12/18/2025 11:15:00 AM to Spring Garden St Station, Philadelphia (USA) arriving at 12/19/2025 8:45:00 AM. 50 Economy ticket for $125 per person are available. Travel duration is 21h 30m
Greyhound US	25h 0m	11:15 AM	Charleston, SC	Bus Station	12:15 PM	Philadelphia	JFK & Broad	Economy	$135	A Bus from Greyhound US goes from Bus Station, Charleston, SC (USA) at 12/18/2025 11:15:00 AM to JFK & Broad, Philadelphia (USA) arriving at 12/19/2025 12:15:00 PM. 50 Economy ticket for $135 per person are available. Travel duration is 25h 0m
Greyhound US	24h 15m	11:15 AM	Charleston, SC	Bus Station	11:30 AM	Philadelphia	IRS Building	Economy	$135	A Bus from Greyhound US goes from Bus Station, Charleston, SC (USA) at 12/18/2025 11:15:00 AM to IRS Building, Philadelphia (USA) arriving at 12/19/2025 11:30:00 AM. 50 Economy ticket for $135 per person are available. Travel duration is 24h 15m

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	19h 30m	11:15 AM	Charleston, SC	Bus Station	6:45 AM	Philadelphia	Spring Garden St Station	Economy	$153	A Bus from Greyhound US goes from Bus Station, Charleston, SC (USA) at 12/19/2025 11:15:00 AM to Spring Garden St Station, Philadelphia (USA) arriving at 12/20/2025 6:45:00 AM. 50 Economy ticket for $153 per person are available. Travel duration is 19h 30m
Greyhound US	21h 30m	11:15 AM	Charleston, SC	Bus Station	8:45 AM	Philadelphia	Spring Garden St Station	Economy	$168	A Bus from Greyhound US goes from Bus Station, Charleston, SC (USA) at 12/19/2025 11:15:00 AM to Spring Garden St Station, Philadelphia (USA) arriving at 12/20/2025 8:45:00 AM. 50 Economy ticket for $168 per person are available. Travel duration is 21h 30m
Greyhound US	24h 15m	11:15 AM	Charleston, SC	Bus Station	11:30 AM	Philadelphia	IRS Building	Economy	$191	A Bus from Greyhound US goes from Bus Station, Charleston, SC (USA) at 12/19/2025 11:15:00 AM to IRS Building, Philadelphia (USA) arriving at 12/20/2025 11:30:00 AM. 50 Economy ticket for $191 per person are available. Travel duration is 24h 15m
Greyhound US	25h 0m	11:15 AM	Charleston, SC	Bus Station	12:15 PM	Philadelphia	JFK & Broad	Economy	$211	A Bus from Greyhound US goes from Bus Station, Charleston, SC (USA) at 12/19/2025 11:15:00 AM to JFK & Broad, Philadelphia (USA) arriving at 12/20/2025 12:15:00 PM. 50 Economy ticket for $211 per person are available. Travel duration is 25h 0m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	21h 30m	11:15 AM	Charleston, SC	Bus Station	8:45 AM	Philadelphia	Spring Garden St Station	Economy	$188	A Bus from Greyhound US goes from Bus Station, Charleston, SC (USA) at 12/20/2025 11:15:00 AM to Spring Garden St Station, Philadelphia (USA) arriving at 12/21/2025 8:45:00 AM. 50 Economy ticket for $188 per person are available. Travel duration is 21h 30m
Greyhound US	25h 0m	11:15 AM	Charleston, SC	Bus Station	12:15 PM	Philadelphia	JFK & Broad	Economy	$202	A Bus from Greyhound US goes from Bus Station, Charleston, SC (USA) at 12/20/2025 11:15:00 AM to JFK & Broad, Philadelphia (USA) arriving at 12/21/2025 12:15:00 PM. 50 Economy ticket for $202 per person are available. Travel duration is 25h 0m
Greyhound US	24h 15m	11:15 AM	Charleston, SC	Bus Station	11:30 AM	Philadelphia	IRS Building	Economy	$202	A Bus from Greyhound US goes from Bus Station, Charleston, SC (USA) at 12/20/2025 11:15:00 AM to IRS Building, Philadelphia (USA) arriving at 12/21/2025 11:30:00 AM. 50 Economy ticket for $202 per person are available. Travel duration is 24h 15m
Greyhound US	19h 30m	11:15 AM	Charleston, SC	Bus Station	6:45 AM	Philadelphia	Spring Garden St Station	Economy	$205	A Bus from Greyhound US goes from Bus Station, Charleston, SC (USA) at 12/20/2025 11:15:00 AM to Spring Garden St Station, Philadelphia (USA) arriving at 12/21/2025 6:45:00 AM. 50 Economy ticket for $205 per person are available. Travel duration is 19h 30m

Did you know that if you travel from Charleston, SC to Philadelphia via Myrtle Beach, SC, you can save more than $49? You can find the corresponding connections below.
- FlixBus
  
  19h 30m
  
  0
  
  11:15 AM
  
  Charleston, SC
  Bus Station
  
  1:40 PM
  
  Myrtle Beach, SC
  Bus Stop
  
  0
  
  Economy
  
  $14
  
  A Bus from FlixBus goes from Bus Station, Charleston, SC (USA) at 12/19/2025 11:15:00 AM to Bus Stop, Myrtle Beach, SC (USA) arriving at 12/19/2025 1:40:00 PM. 50 Economy ticket for $14 per person are available. Travel duration is 2h 25m
- FlixBus
  
  16h 50m
  
  0
  
  1:55 PM
  
  Myrtle Beach, SC
  Bus Stop
  
  6:45 AM
  
  Philadelphia
  Spring Garden St Station
  
  0
  
  Economy
  
  $125
  
  A Bus from FlixBus goes from Bus Stop, Myrtle Beach, SC (USA) at 12/19/2025 1:55:00 PM to Spring Garden St Station, Philadelphia (USA) arriving at 12/20/2025 6:45:00 AM. 50 Economy ticket for $125 per person are available. Travel duration is 16h 50m
Travel time is the same as the direct connection, but you will save $49

Best Price Offer: The price for the cheapest bus from Charleston, SC to Philadelphia is $98 on 12/15/2025. Flexible travelers save on ticket prices.

Facts about the bus from Charleston, SC to Philadelphia

Compare all providers like Greyhound US that travel 3 times every day by bus from Charleston, SC to Philadelphia in one click! Book your bus ticket from Charleston, SC to Philadelphia starting from $98!

Cheapest Bus	$98
Fastest Bus	19h 30m
Earliest Bus	11:15 AM
Latest Bus	11:15 AM
Daily Bus Routes	3 Ø
Distance	562.0 miles
Bus Companies	Greyhound US

Cheapest bus connections from Charleston, SC to Philadelphia

Every day, 3 buses from 1 bus companies leave Charleston, SC for Philadelphia: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/17/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 12/14

Monday 12/15

Tuesday 12/16

Wednesday 12/17

$101

Thursday 12/18

$124

Friday 12/19

$153

Saturday 12/20

$188

Sunday 12/21

Monday 12/22

Tuesday 12/23

Wednesday 12/24

Thursday 12/25

Friday 12/26

Saturday 12/27

Sunday 12/28

Monday 12/29

Tuesday 12/30

Wednesday 12/31

Thursday 01/01

Friday 01/02

Saturday 01/03

Sunday 01/04

Monday 01/05

Tuesday 01/06

Wednesday 01/07

Thursday 01/08

Friday 01/09

Saturday 01/10

How to save money travelling from Charleston, SC to Philadelphia

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Charleston, SC to Philadelphia in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Charleston, SC to Philadelphia, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Charleston, SC to Philadelphia are also emptier.

All bus stations and stops in Charleston, SC and Philadelphia

In the map below, you can see where to find all bus stations in Charleston, SC and Philadelphia.

Bus Station

Dorchester Rd 3610

BI-LO Shopping Center Downtown

Meeting St 445

Central Bus Station

Filbert St 1001

Market St

Spring Garden St Station

Spring Garden St & 2nd St

JFK & Broad

John F Kennedy Blvd 1401

30th Street Station

Market St 2955

Service and Comfort on the bus from Charleston, SC to Philadelphia

Want to know which seat classes are available on the buses from Charleston, SC to Philadelphia? Or which bus companies serve the route Charleston, SC to Philadelphia? Below you will find answers to your questions.

FAQs about the Charleston, SC to Philadelphia bus

How much does a Charleston, SC Philadelphia bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $98 and takes 27h 15m to reach Philadelphia. Compare offers to save money!

How much could I save by comparing buses from Charleston, SC to Philadelphia?

This route is offered by 1 companies with a range of ticket prices between $98 and $211. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Philadelphia.

On average, how many connections are available from Charleston, SC to Philadelphia each day?

Every day, the Charleston, SC to Philadelphia bus route is served by approximately 3 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Charleston, SC to Philadelphia take?

The fastest bus from Charleston, SC to Philadelphia is offered by Greyhound US and takes 19h 30m. Bus tickets for this connection cost $101. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Charleston, SC to Philadelphia?

The earliest bus arriving in Philadelphia from Charleston, SC starts at 11:15 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Charleston, SC to Philadelphia?

The latest bus trip departing from Charleston, SC for Philadelphia starts at 11:15 AM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Charleston, SC Philadelphia route?

When traveling by bus from Charleston, SC to Philadelphia, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Charleston, SC and Philadelphia?

You can check all the direct connections between Charleston, SC and Philadelphia by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Charleston, SC to Philadelphia bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Charleston, SC Philadelphia bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Charleston, SC Philadelphia bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Charleston, SC to Philadelphia on your planned travel date.

How does CheckMyBus find the best bus deals from Charleston, SC to Philadelphia?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 3 daily trips between Charleston, SC and Philadelphia. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Charleston, SC to Philadelphia?

Prices and availability for 3 trips between Charleston, SC and Philadelphia change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Charleston, SC to Philadelphia

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Charleston, SC and to Philadelphia

Here’s an overview of the most popular bus routes to Charleston, SC and to Philadelphia. Simply click on the connection of your choice, and you will find all the details about your bus route!