Which bus from Denver to Port Saint Lucie, FL is the cheapest?

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Compare all timetables for the bus from Denver to Port Saint Lucie, FL

Here is a selection of the cheapest bus trips from the schedule from Denver to Port Saint Lucie, FL from various bus operators like Greyhound US for the next days.

today
tomorrow
Monday
Tuesday
$221
Wednesday
$226
Thursday
Friday
$225

Cheapest bus trips Tuesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 53h 5m 8:10 PM Denver Union Station 3:15 AM Port Saint Lucie, FL SW Gatlin Blvd & SW Brescia St Bus Stop  Economy $221
Greyhound US 52h 10m 7:25 PM Denver Union Station 1:35 AM Port Saint Lucie, FL SW Gatlin Blvd & SW Brescia St Bus Stop  Economy $222
  • Did you know that if you travel from Denver to Port Saint Lucie, FL via Orlando, FL, you can save more than $38? You can find the corresponding connections below.
    • Greyhound US
      53h 50m
      0
      7:25 PM
      Denver
      Union Station
      5:20 PM
      Orlando, FL
      Florida Mall
      0
      Greyhound US
      Economy
      $161
      • Waiting Time 7h 25m
    • FlixBus
      2h 30m
      0
      12:45 AM
      Orlando, FL
      Bus Station
      3:15 AM
      Port Saint Lucie, FL
      SW Gatlin Blvd & SW Brescia St Bus Stop
      0
      FlixBus
      Economy
      $22
    Travel Time is 0h 20m shorter, and you will save $38

Cheapest bus trips Wednesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 52h 10m 7:25 PM Denver Union Station 1:35 AM Port Saint Lucie, FL RaceTrac Gas Station  Economy $226
Greyhound US 53h 5m 8:10 PM Denver Union Station 3:15 AM Port Saint Lucie, FL RaceTrac Gas Station  Economy $226
  • Did you know that if you travel from Denver to Port Saint Lucie, FL via Orlando, FL, you can save more than $43? You can find the corresponding connections below.
    • Greyhound US
      53h 50m
      0
      7:25 PM
      Denver
      Union Station
      5:20 PM
      Orlando, FL
      Florida Mall
      0
      Greyhound US
      Economy
      $161
      • Waiting Time 7h 25m
    • FlixBus
      2h 30m
      0
      12:45 AM
      Orlando, FL
      Bus Station
      3:15 AM
      Port Saint Lucie, FL
      SW Gatlin Blvd & SW Brescia St Bus Stop
      0
      FlixBus
      Economy
      $22
    Travel Time is 0h 20m shorter, and you will save $43

Cheapest bus trips Friday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 53h 5m 8:10 PM Denver Union Station 3:15 AM Port Saint Lucie, FL RaceTrac Gas Station  Economy $225
Greyhound US 52h 10m 7:25 PM Denver Union Station 1:35 AM Port Saint Lucie, FL RaceTrac Gas Station  Economy $226
  • Did you know that if you travel from Denver to Port Saint Lucie, FL via Orlando, FL, you can save more than $42? You can find the corresponding connections below.
    • Greyhound US
      53h 50m
      0
      7:25 PM
      Denver
      Union Station
      5:20 PM
      Orlando, FL
      Florida Mall
      0
      Greyhound US
      Economy
      $161
      • Waiting Time 7h 25m
    • FlixBus
      2h 30m
      0
      12:45 AM
      Orlando, FL
      Bus Station
      3:15 AM
      Port Saint Lucie, FL
      SW Gatlin Blvd & SW Brescia St Bus Stop
      0
      FlixBus
      Economy
      $22
    Travel Time is 0h 20m shorter, and you will save $42

Best Price Offer: The price for the cheapest bus from Denver to Port Saint Lucie, FL is $216 on 4/7/2026. Flexible travelers save on ticket prices.


Facts about the bus from Denver to Port Saint Lucie, FL

Compare all providers like Greyhound US that travel 2 times every day by bus from Denver to Port Saint Lucie, FL in one click! Book your bus ticket from Denver to Port Saint Lucie, FL starting from $216!

Cheapest Bus $216
Fastest Bus 54h 10m
Earliest Bus 7:25 PM
Latest Bus 8:10 PM
Daily Bus Routes 2 Ø
Distance 1,652.7 miles
Bus Companies Greyhound US

Cheapest bus connections from Denver to Port Saint Lucie, FL

Every day, 2 buses from 1 bus companies leave Denver for Port Saint Lucie, FL: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 03/21/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 03/15
Monday 03/16
Tuesday 03/17
Wednesday 03/18
Thursday 03/19
Friday 03/20
Saturday 03/21
Sunday 03/22
Monday 03/23
Tuesday 03/24
$221
Wednesday 03/25
$226
Thursday 03/26
Friday 03/27
$225
Saturday 03/28
Sunday 03/29
Monday 03/30
Tuesday 03/31
$222
Wednesday 04/01
Thursday 04/02
$223
Friday 04/03
Saturday 04/04
Sunday 04/05
Monday 04/06
$220
Tuesday 04/07
$216
Wednesday 04/08
Thursday 04/09
$222
Friday 04/10
$218
Saturday 04/11

How to save money travelling from Denver to Port Saint Lucie, FL

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Denver to Port Saint Lucie, FL in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Denver to Port Saint Lucie, FL, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Denver to Port Saint Lucie, FL are also emptier.

All bus stations and stops in Denver and Port Saint Lucie, FL

In the map below, you can see where to find all bus stations in Denver and Port Saint Lucie, FL.

Service and Comfort on the bus from Denver to Port Saint Lucie, FL

Want to know which seat classes are available on the buses from Denver to Port Saint Lucie, FL? Or which bus companies serve the route Denver to Port Saint Lucie, FL? Below you will find answers to your questions.

FAQs about the Denver to Port Saint Lucie, FL bus

How much does a Denver Port Saint Lucie, FL bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $216 and takes 55h 5m to reach Port Saint Lucie, FL. Compare offers to save money!

How much could I save by comparing buses from Denver to Port Saint Lucie, FL?

This route is offered by 1 companies with a range of ticket prices between $216 and $226. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Port Saint Lucie, FL.

On average, how many connections are available from Denver to Port Saint Lucie, FL each day?

Every day, the Denver to Port Saint Lucie, FL bus route is served by approximately 2 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Denver to Port Saint Lucie, FL take?

The fastest bus from Denver to Port Saint Lucie, FL is offered by Greyhound US and takes 54h 10m. Bus tickets for this connection cost $222. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Denver to Port Saint Lucie, FL?

The earliest bus arriving in Port Saint Lucie, FL from Denver starts at 7:25 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Denver to Port Saint Lucie, FL?

The latest bus trip departing from Denver for Port Saint Lucie, FL starts at 8:10 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Denver Port Saint Lucie, FL route?

When traveling by bus from Denver to Port Saint Lucie, FL, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Denver and Port Saint Lucie, FL?

You can check all the direct connections between Denver and Port Saint Lucie, FL by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Denver to Port Saint Lucie, FL bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Denver Port Saint Lucie, FL bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Denver Port Saint Lucie, FL bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Denver to Port Saint Lucie, FL on your planned travel date.

How does CheckMyBus find the best bus deals from Denver to Port Saint Lucie, FL?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 2 daily trips between Denver and Port Saint Lucie, FL. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Denver to Port Saint Lucie, FL?

Prices and availability for 2 trips between Denver and Port Saint Lucie, FL change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Denver to Port Saint Lucie, FL

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Denver and to Port Saint Lucie, FL

Here’s an overview of the most popular bus routes to Denver and to Port Saint Lucie, FL. Simply click on the connection of your choice, and you will find all the details about your bus route!
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Popular Airport Shuttles to Denver and to Port Saint Lucie, FL
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