Bus from Des Moines, IA to Cleveland from $110

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Compare all timetables for the bus from Des Moines, IA to Cleveland

Here is a selection of the cheapest bus trips from the schedule from Des Moines, IA to Cleveland from various bus operators like Greyhound US for the next days.
today
from $166
tomorrow
Thursday
from $124
Friday
Saturday
Sunday
from $110
Monday

Cheapest bus trips today

Prices are for one way and one person
  • Greyhound US
    29h 5m
    0
    5:30 AM
    Des Moines, IA
    Jefferson/Trailways Depot
    10:35 AM
    Cleveland
    Greyhound Bus Station
    0
    Greyhound US
    Economy
    $166
  • Did you know that if you travel from Des Moines, IA to Cleveland via Chicago, you can save more than $66? You can find the corresponding connections below.
    • FlixBus
      27h 25m
      0
      5:30 AM
      Des Moines, IA
      Jefferson/Trailways Depot
      1:35 PM
      Chicago
      Downtown Bus Station
      0
      FlixBus
      Economy
      $48
      • Waiting Time 9h 40m
    • Busbud
      9h 40m
      0
      11:15 PM
      Chicago
      Downtown Bus Station
      8:55 AM
      Cleveland
      Greyhound Bus Station
      0
      Busbud
      Economy
      $52
    Travel Time is 1h 40m shorter, and you will save $66

Cheapest bus trips Thursday

Prices are for one way and one person
  • Greyhound US
    20h 5m
    0
    5:30 AM
    Des Moines, IA
    Jefferson/Trailways Depot
    1:35 AM
    Cleveland
    Greyhound Bus Station
    0
    Greyhound US
    Economy
    $124
  • Did you know that if you travel from Des Moines, IA to Cleveland via Chicago, you can save more than $24? You can find the corresponding connections below.
    • FlixBus
      27h 25m
      0
      5:30 AM
      Des Moines, IA
      Jefferson/Trailways Depot
      1:35 PM
      Chicago
      Downtown Bus Station
      0
      FlixBus
      Economy
      $48
      • Waiting Time 9h 40m
    • Busbud
      9h 40m
      0
      11:15 PM
      Chicago
      Downtown Bus Station
      8:55 AM
      Cleveland
      Greyhound Bus Station
      0
      Busbud
      Economy
      $52
    Travel time is 7h 20m longer, but you will save $24

Cheapest bus trips Sunday

Prices are for one way and one person
  • Greyhound US
    20h 5m
    0
    5:30 AM
    Des Moines, IA
    Jefferson/Trailways Depot
    1:35 AM
    Cleveland
    Greyhound Bus Station
    0
    Greyhound US
    Economy
    $110

Facts about the bus from Des Moines, IA to Cleveland

Compare all providers like Greyhound US that travel 1 times every day by bus from Des Moines, IA to Cleveland in one click! Book your bus ticket from Des Moines, IA to Cleveland starting from $110!

Cheapest Bus $110
Fastest Bus 20h 5m
Earliest Bus 5:30 AM
Latest Bus 5:30 AM
Daily Bus Routes 1 Ø
Distance 617.8 miles
Bus Companies Greyhound US

Cheapest bus connections from Des Moines, IA to Cleveland

Every day, 1 buses from 1 bus companies leave Des Moines, IA for Cleveland: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 06/25/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 06/22
Monday 06/23
Tuesday 06/24
$166
Wednesday 06/25
Thursday 06/26
$124
Friday 06/27
Saturday 06/28
Sunday 06/29
$110
Monday 06/30
Tuesday 07/01
Wednesday 07/02
Thursday 07/03
Friday 07/04
Saturday 07/05
Sunday 07/06
Monday 07/07
Tuesday 07/08
Wednesday 07/09
Thursday 07/10
Friday 07/11
Saturday 07/12
Sunday 07/13
Monday 07/14
Tuesday 07/15
Wednesday 07/16
Thursday 07/17
Friday 07/18
Saturday 07/19

How to save money travelling from Des Moines, IA to Cleveland

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Des Moines, IA to Cleveland in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Des Moines, IA to Cleveland, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Des Moines, IA to Cleveland are also emptier.

Beloved bus companies from Des Moines, IA to Cleveland

These are the most booked bus companies between Des Moines, IA to Cleveland from our users.

Greyhound US from Des Moines, IA to Cleveland

Greyhound US

Here you will find the key facts about the Greyhound US bus route Des Moines, IA to Cleveland:

Cheapest Price $110
Fastest Bus 20h 5m
Earliest Bus 5:30 AM
Last Bus 5:30 AM
Daily Connections 1 Ø
Found on 6/20/2025

All bus stations and stops in Des Moines, IA and Cleveland

In the map below, you can see where to find all bus stations in Des Moines, IA and Cleveland.

Service and Comfort on the bus from Des Moines, IA to Cleveland

Want to know which seat classes are available on the buses from Des Moines, IA to Cleveland? Or which bus companies serve the route Des Moines, IA to Cleveland? Below you will find answers to your questions.

FAQs about the Des Moines, IA to Cleveland bus

How much does a Des Moines, IA Cleveland bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $110 and takes 20h 5m to reach Cleveland. Compare offers to save money!

How much could I save by comparing buses from Des Moines, IA to Cleveland?

This route is offered by 1 companies with a range of ticket prices between $110 and $166. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Cleveland.

On average, how many connections are available from Des Moines, IA to Cleveland each day?

Every day, the Des Moines, IA to Cleveland bus route is served by approximately 1 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Des Moines, IA to Cleveland take?

The fastest bus from Des Moines, IA to Cleveland is offered by Greyhound US and takes 20h 5m. Bus tickets for this connection cost $124. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Des Moines, IA to Cleveland?

The earliest bus arriving in Cleveland from Des Moines, IA starts at 5:30 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Des Moines, IA to Cleveland?

The latest bus trip departing from Des Moines, IA for Cleveland starts at 5:30 AM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Des Moines, IA Cleveland route?

When traveling by bus from Des Moines, IA to Cleveland, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Des Moines, IA and Cleveland?

You can check all the direct connections between Des Moines, IA and Cleveland by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Des Moines, IA to Cleveland bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Des Moines, IA Cleveland bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Des Moines, IA Cleveland bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Des Moines, IA to Cleveland on your planned travel date.

Available seat classes which are offered on the bus route Des Moines, IA to Cleveland

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Des Moines, IA and to Cleveland

Here’s an overview of the most popular bus routes to Des Moines, IA and to Cleveland. Simply click on the connection of your choice, and you will find all the details about your bus route!
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Columbus, OH to Cleveland bus Columbus, OH to Cleveland bus
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Bus from Chicago to Cleveland Bus from Chicago to Cleveland
Bus Pittsburgh - Cleveland Bus Pittsburgh - Cleveland
Popular Airport Shuttles to Des Moines, IA and to Cleveland
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