Bus from Des Moines, IA to Houston from $224

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Compare all timetables for the bus from Des Moines, IA to Houston

Here is a selection of the cheapest bus trips from the schedule from Des Moines, IA to Houston from various bus operators like Greyhound US for the next days.
today
tomorrow
Tuesday
Wednesday
Thursday
Friday
from $224
Saturday

Cheapest bus trips Friday

Prices are for one way and one person
  • Greyhound US
    47h 50m
    0
    5:30 AM
    Des Moines, IA
    Jefferson/Trailways Depot
    5:20 AM
    Houston
    Downtown Houston
    0
    Greyhound US
    Economy
    $224
  • Greyhound US
    55h 40m
    0
    5:30 AM
    Des Moines, IA
    Jefferson/Trailways Depot
    1:10 PM
    Houston
    Uptown/Upper Kirby
    0
    Greyhound US
    Economy
    $224
  • Greyhound US
    41h 0m
    0
    5:30 AM
    Des Moines, IA
    Jefferson/Trailways Depot
    10:30 PM
    Houston
    Harrisburg Blvd Station
    0
    Greyhound US
    Economy
    $225
  • Did you know that if you travel from Des Moines, IA to Houston via Chicago, you can save more than $112? You can find the corresponding connections below.
    • FlixBus
      41h 45m
      0
      5:30 AM
      Des Moines, IA
      Jefferson/Trailways Depot
      1:35 PM
      Chicago
      Downtown Bus Station
      0
      FlixBus
      Economy
      $44
      • Waiting Time 7h 0m
    • Busbud
      26h 40m
      0
      8:35 PM
      Chicago
      95th Red Line Station
      11:15 PM
      Houston
      Harrisburg Blvd Station
      0
      Busbud
      Economy
      $68
    Travel time is 0h 45m longer, but you will save $112

Facts about the bus from Des Moines, IA to Houston

Compare all providers like Greyhound US that travel 3 times every day by bus from Des Moines, IA to Houston in one click! Book your bus ticket from Des Moines, IA to Houston starting from $224!

Cheapest Bus $224
Fastest Bus 41h 0m
Earliest Bus 5:30 AM
Latest Bus 5:30 AM
Daily Bus Routes 3 Ø
Distance 824.3 miles
Bus Companies Greyhound US

Cheapest bus connections from Des Moines, IA to Houston

Every day, 3 buses from 1 bus companies leave Des Moines, IA for Houston: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 06/01/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 06/01
Monday 06/02
$225
Tuesday 06/03
Wednesday 06/04
Thursday 06/05
Friday 06/06
$224
Saturday 06/07
Sunday 06/08
$236
Monday 06/09
Tuesday 06/10
Wednesday 06/11
Thursday 06/12
Friday 06/13
Saturday 06/14
Sunday 06/15
Monday 06/16
Tuesday 06/17
Wednesday 06/18
Thursday 06/19
Friday 06/20
Saturday 06/21
Sunday 06/22
Monday 06/23
Tuesday 06/24
Wednesday 06/25
Thursday 06/26
Friday 06/27
Saturday 06/28

How to save money travelling from Des Moines, IA to Houston

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Des Moines, IA to Houston in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Des Moines, IA to Houston, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Des Moines, IA to Houston are also emptier.

Beloved bus companies from Des Moines, IA to Houston

These are the most booked bus companies between Des Moines, IA to Houston from our users.

Greyhound US from Des Moines, IA to Houston

Greyhound US

Here you will find the key facts about the Greyhound US bus route Des Moines, IA to Houston:

Cheapest Price $224
Fastest Bus 41h 0m
Earliest Bus 5:30 AM
Last Bus 5:30 AM
Daily Connections 3 Ø
Found on 5/29/2025

All bus stations and stops in Des Moines, IA and Houston

In the map below, you can see where to find all bus stations in Des Moines, IA and Houston.

Service and Comfort on the bus from Des Moines, IA to Houston

Want to know which seat classes are available on the buses from Des Moines, IA to Houston? Or which bus companies serve the route Des Moines, IA to Houston? Below you will find answers to your questions.

FAQs about the Des Moines, IA to Houston bus

How much does a Des Moines, IA Houston bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $224 and takes 47h 50m to reach Houston. Compare offers to save money!

How much could I save by comparing buses from Des Moines, IA to Houston?

This route is offered by 1 companies with a range of ticket prices between $224 and $225. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Houston.

On average, how many connections are available from Des Moines, IA to Houston each day?

Every day, the Des Moines, IA to Houston bus route is served by approximately 3 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Des Moines, IA to Houston take?

The fastest bus from Des Moines, IA to Houston is offered by Greyhound US and takes 41h 0m. Bus tickets for this connection cost $225. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Des Moines, IA to Houston?

The earliest bus arriving in Houston from Des Moines, IA starts at 5:30 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Des Moines, IA to Houston?

The latest bus trip departing from Des Moines, IA for Houston starts at 5:30 AM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Des Moines, IA Houston route?

When traveling by bus from Des Moines, IA to Houston, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Des Moines, IA and Houston?

You can check all the direct connections between Des Moines, IA and Houston by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Des Moines, IA to Houston bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Des Moines, IA Houston bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Des Moines, IA Houston bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Des Moines, IA to Houston on your planned travel date.

Available seat classes which are offered on the bus route Des Moines, IA to Houston

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Des Moines, IA and to Houston

Here’s an overview of the most popular bus routes to Des Moines, IA and to Houston. Simply click on the connection of your choice, and you will find all the details about your bus route!
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Bus to Des Moines, IA from Minneapolis Bus to Des Moines, IA from Minneapolis
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Bus Plano, TX - Houston Bus Plano, TX - Houston
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Bus to Houston from Atlanta, GA Bus to Houston from Atlanta, GA
Popular Airport Shuttles to Des Moines, IA and to Houston
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