Bus Jacksonville, FL to Key West, FL

Compare all timetables for the bus from Jacksonville, FL to Key West, FL

Here is a selection of the cheapest bus trips from the schedule from Jacksonville, FL to Key West, FL from various bus operators like FlixBus for the next days.

today

$83

tomorrow

$74

Sunday

Monday

$73

Tuesday

Wednesday

$77

Thursday

$81

Cheapest bus trips today
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	15h 0m	6:30 PM	Jacksonville, FL	Amtrak Train Station	9:30 AM	Key West, FL	Bus Stop		Economy	$83	A Bus from FlixBus goes from Amtrak Train Station, Jacksonville, FL (USA) at 12/5/2025 6:30:00 PM to Bus Stop, Key West, FL (USA) arriving at 12/6/2025 9:30:00 AM. 50 Economy ticket for $83 per person are available. Travel duration is 15h 0m
	FlixBus	17h 25m	10:05 PM	Jacksonville, FL	Amtrak Train Station	3:30 PM	Key West, FL	Bus Stop		Economy	$83	A Bus from FlixBus goes from Amtrak Train Station, Jacksonville, FL (USA) at 12/5/2025 10:05:00 PM to Bus Stop, Key West, FL (USA) arriving at 12/6/2025 3:30:00 PM. 50 Economy ticket for $83 per person are available. Travel duration is 17h 25m

Did you know that if you travel from Jacksonville, FL to Key West, FL via Orlando, FL, you can save more than $10? You can find the corresponding connections below.
- FlixBus
  
  15h 0m
  
  0
  
  6:30 PM
  
  Jacksonville, FL
  Amtrak Train Station
  
  9:05 PM
  
  Orlando, FL
  Bus Station
  
  0
  
  Economy
  
  $22
  
  A Bus from FlixBus goes from Amtrak Train Station, Jacksonville, FL (USA) at 12/6/2025 6:30:00 PM to Bus Station, Orlando, FL (USA) arriving at 12/6/2025 9:05:00 PM. 50 Economy ticket for $22 per person are available. Travel duration is 2h 35m
- Busbud
  
  10h 55m
  
  0
  
  10:35 PM
  
  Orlando, FL
  Bus Station
  
  9:30 AM
  
  Key West, FL
  Bus Stop
  
  0
  
  Economy
  
  $50
  
  A Bus from Busbud goes from Bus Station, Orlando, FL (USA) at 12/6/2025 10:35:00 PM to Bus Stop, Key West, FL (USA) arriving at 12/7/2025 9:30:00 AM. 50 Economy ticket for $50 per person are available. Travel duration is 10h 55m
Travel time is the same as the direct connection, but you will save $10

Cheapest bus trips tomorrow
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	17h 25m	10:05 PM	Jacksonville, FL	Amtrak Train Station	3:30 PM	Key West, FL	Bus Stop		Economy	$74	A Bus from FlixBus goes from Amtrak Train Station, Jacksonville, FL (USA) at 12/6/2025 10:05:00 PM to Bus Stop, Key West, FL (USA) arriving at 12/7/2025 3:30:00 PM. 50 Economy ticket for $74 per person are available. Travel duration is 17h 25m
	FlixBus	15h 0m	6:30 PM	Jacksonville, FL	Amtrak Train Station	9:30 AM	Key West, FL	Bus Stop		Economy	$75	A Bus from FlixBus goes from Amtrak Train Station, Jacksonville, FL (USA) at 12/6/2025 6:30:00 PM to Bus Stop, Key West, FL (USA) arriving at 12/7/2025 9:30:00 AM. 50 Economy ticket for $75 per person are available. Travel duration is 15h 0m

Cheapest bus trips Monday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	15h 0m	6:30 PM	Jacksonville, FL	Amtrak Train Station	9:30 AM	Key West, FL	Bus Stop		Economy	$73	A Bus from FlixBus goes from Amtrak Train Station, Jacksonville, FL (USA) at 12/8/2025 6:30:00 PM to Bus Stop, Key West, FL (USA) arriving at 12/9/2025 9:30:00 AM. 50 Economy ticket for $73 per person are available. Travel duration is 15h 0m
	FlixBus	17h 25m	10:05 PM	Jacksonville, FL	Amtrak Train Station	3:30 PM	Key West, FL	Bus Stop		Economy	$73	A Bus from FlixBus goes from Amtrak Train Station, Jacksonville, FL (USA) at 12/8/2025 10:05:00 PM to Bus Stop, Key West, FL (USA) arriving at 12/9/2025 3:30:00 PM. 50 Economy ticket for $73 per person are available. Travel duration is 17h 25m

Cheapest bus trips Wednesday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	15h 0m	6:30 PM	Jacksonville, FL	Amtrak Train Station	9:30 AM	Key West, FL	Bus Stop		Economy	$77	A Bus from FlixBus goes from Amtrak Train Station, Jacksonville, FL (USA) at 12/10/2025 6:30:00 PM to Bus Stop, Key West, FL (USA) arriving at 12/11/2025 9:30:00 AM. 50 Economy ticket for $77 per person are available. Travel duration is 15h 0m
	FlixBus	17h 25m	10:05 PM	Jacksonville, FL	Amtrak Train Station	3:30 PM	Key West, FL	Bus Stop		Economy	$79	A Bus from FlixBus goes from Amtrak Train Station, Jacksonville, FL (USA) at 12/10/2025 10:05:00 PM to Bus Stop, Key West, FL (USA) arriving at 12/11/2025 3:30:00 PM. 50 Economy ticket for $79 per person are available. Travel duration is 17h 25m

Did you know that if you travel from Jacksonville, FL to Key West, FL via Miami Airport, you can save more than $8? You can find the corresponding connections below.
- FlixBus
  
  16h 30m
  
  0
  
  5:00 PM
  
  Jacksonville, FL
  Amtrak Train Station
  
  12:25 AM
  
  Miami Airport
  Miami Airport - Intermodal Station
  
  0
  
  Economy
  
  $49
  
  A Bus from FlixBus goes from Amtrak Train Station, Jacksonville, FL (USA) at 12/10/2025 5:00:00 PM to Miami Airport - Intermodal Station, Miami Airport (USA) arriving at 12/11/2025 12:25:00 AM. 50 Economy ticket for $49 per person are available. Travel duration is 7h 25m
- Busbud
  
  4h 30m
  
  0
  
  5:00 AM
  
  Miami Airport
  Miami Airport - Terminal J
  
  9:30 AM
  
  Key West, FL
  Bus Stop
  
  0
  
  Economy
  
  $20
  
  A Bus from Busbud goes from Miami Airport - Terminal J, Miami Airport (USA) at 12/11/2025 5:00:00 AM to Bus Stop, Key West, FL (USA) arriving at 12/11/2025 9:30:00 AM. 50 Economy ticket for $20 per person are available. Travel duration is 4h 30m
Travel time is 1h 30m longer, but you will save $8

Cheapest bus trips Thursday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	17h 25m	10:05 PM	Jacksonville, FL	Amtrak Train Station	3:30 PM	Key West, FL	Bus Stop		Economy	$81	A Bus from FlixBus goes from Amtrak Train Station, Jacksonville, FL (USA) at 12/11/2025 10:05:00 PM to Bus Stop, Key West, FL (USA) arriving at 12/12/2025 3:30:00 PM. 50 Economy ticket for $81 per person are available. Travel duration is 17h 25m
	FlixBus	15h 0m	6:30 PM	Jacksonville, FL	Amtrak Train Station	9:30 AM	Key West, FL	Bus Stop		Economy	$82	A Bus from FlixBus goes from Amtrak Train Station, Jacksonville, FL (USA) at 12/11/2025 6:30:00 PM to Bus Stop, Key West, FL (USA) arriving at 12/12/2025 9:30:00 AM. 50 Economy ticket for $82 per person are available. Travel duration is 15h 0m

Did you know that if you travel from Jacksonville, FL to Key West, FL via Miami Airport, you can save more than $12? You can find the corresponding connections below.
- FlixBus
  
  16h 30m
  
  0
  
  5:00 PM
  
  Jacksonville, FL
  Amtrak Train Station
  
  12:25 AM
  
  Miami Airport
  Miami Airport - Intermodal Station
  
  0
  
  Economy
  
  $49
  
  A Bus from FlixBus goes from Amtrak Train Station, Jacksonville, FL (USA) at 12/10/2025 5:00:00 PM to Miami Airport - Intermodal Station, Miami Airport (USA) arriving at 12/11/2025 12:25:00 AM. 50 Economy ticket for $49 per person are available. Travel duration is 7h 25m
- Busbud
  
  4h 30m
  
  0
  
  5:00 AM
  
  Miami Airport
  Miami Airport - Terminal J
  
  9:30 AM
  
  Key West, FL
  Bus Stop
  
  0
  
  Economy
  
  $20
  
  A Bus from Busbud goes from Miami Airport - Terminal J, Miami Airport (USA) at 12/11/2025 5:00:00 AM to Bus Stop, Key West, FL (USA) arriving at 12/11/2025 9:30:00 AM. 50 Economy ticket for $20 per person are available. Travel duration is 4h 30m
Travel time is 1h 30m longer, but you will save $12

Best Price Offer: The price for the cheapest bus from Jacksonville, FL to Key West, FL is $73 on 12/3/2025. Flexible travelers save on ticket prices.

Facts about the bus from Jacksonville, FL to Key West, FL

Compare all providers like FlixBus that travel 2 times every day by bus from Jacksonville, FL to Key West, FL in one click! Book your bus ticket from Jacksonville, FL to Key West, FL starting from $73!

Cheapest Bus	$73
Fastest Bus	15h 0m
Earliest Bus	6:30 PM
Latest Bus	10:05 PM
Daily Bus Routes	2 Ø
Distance	399.1 miles
Bus Companies	FlixBus

Cheapest bus connections from Jacksonville, FL to Key West, FL

Every day, 2 buses from 1 bus companies leave Jacksonville, FL for Key West, FL: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/05/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 11/30

Monday 12/01

Tuesday 12/02

Wednesday 12/03

Thursday 12/04

Friday 12/05

$83

Saturday 12/06

$74

Sunday 12/07

Monday 12/08

$73

Tuesday 12/09

Wednesday 12/10

$77

Thursday 12/11

$81

Friday 12/12

Saturday 12/13

Sunday 12/14

Monday 12/15

Tuesday 12/16

Wednesday 12/17

Thursday 12/18

Friday 12/19

Saturday 12/20

Sunday 12/21

Monday 12/22

Tuesday 12/23

Wednesday 12/24

Thursday 12/25

Friday 12/26

Saturday 12/27

How to save money travelling from Jacksonville, FL to Key West, FL

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Jacksonville, FL to Key West, FL in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Jacksonville, FL to Key West, FL, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Jacksonville, FL to Key West, FL are also emptier.

All bus stations and stops in Jacksonville, FL and Key West, FL

In the map below, you can see where to find all bus stations in Jacksonville, FL and Key West, FL.

Downtown Bus Stop

West Forsyth Street 1111

Central Bus Station

Old St. Augustine Rd

Old St. Augustine Rd 10584-13

Beaver St. & Ocean St. Bus Stop

Friendship Fountain

Bus Stop

S Roosevelt Blvd 3535

Caroline St

Caroline St 900-998

Service and Comfort on the bus from Jacksonville, FL to Key West, FL

Want to know which seat classes are available on the buses from Jacksonville, FL to Key West, FL? Or which bus companies serve the route Jacksonville, FL to Key West, FL? Below you will find answers to your questions.

FAQs about the Jacksonville, FL to Key West, FL bus

How much does a Jacksonville, FL Key West, FL bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $73 and takes 15h 0m to reach Key West, FL. Compare offers to save money!

How much could I save by comparing buses from Jacksonville, FL to Key West, FL?

This route is offered by 1 companies with a range of ticket prices between $73 and $83. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Key West, FL.

On average, how many connections are available from Jacksonville, FL to Key West, FL each day?

Every day, the Jacksonville, FL to Key West, FL bus route is served by approximately 2 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Jacksonville, FL to Key West, FL take?

The fastest bus from Jacksonville, FL to Key West, FL is offered by FlixBus and takes 15h 0m. Bus tickets for this connection cost $83. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Jacksonville, FL to Key West, FL?

The earliest bus arriving in Key West, FL from Jacksonville, FL starts at 6:30 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Jacksonville, FL to Key West, FL?

The latest bus trip departing from Jacksonville, FL for Key West, FL starts at 10:05 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Jacksonville, FL Key West, FL route?

When traveling by bus from Jacksonville, FL to Key West, FL, passengers can travel with FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Jacksonville, FL and Key West, FL?

You can check all the direct connections between Jacksonville, FL and Key West, FL by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus.

What can I take with me on the Jacksonville, FL to Key West, FL bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Jacksonville, FL Key West, FL bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Jacksonville, FL Key West, FL bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Jacksonville, FL to Key West, FL on your planned travel date.

Available seat classes which are offered on the bus route Jacksonville, FL to Key West, FL

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Jacksonville, FL and to Key West, FL

Here’s an overview of the most popular bus routes to Jacksonville, FL and to Key West, FL. Simply click on the connection of your choice, and you will find all the details about your bus route!