Bus from Key West, FL to Jacksonville, FL from $71

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Compare all timetables for the bus from Key West, FL to Jacksonville, FL

Here is a selection of the cheapest bus trips from the schedule from Key West, FL to Jacksonville, FL from various bus operators like Greyhound US for the next days.

today
$79
tomorrow
$92
Wednesday
Thursday
$77
Friday
$78
Saturday
$71
Sunday
$73

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 17h 30m 1:30 PM Key West, FL Bus Stop 7:00 AM Jacksonville, FL Downtown Bus Stop  Economy $79
Greyhound US 15h 50m 5:00 PM Key West, FL Bus Stop 8:50 AM Jacksonville, FL Downtown Bus Stop  Economy $79
  • Did you know that if you travel from Key West, FL to Jacksonville, FL via Miami Airport, you can save more than $14? You can find the corresponding connections below.
    • Greyhound US
      15h 50m
      0
      5:00 PM
      Key West, FL
      Bus Stop
      9:15 PM
      Miami Airport
      Miami Airport - Terminal J
      0
      Greyhound US
      Economy
      $21
      • Waiting Time 2h 10m
    • Greyhound US
      9h 25m
      0
      11:25 PM
      Miami Airport
      Miami Airport - Terminal J
      8:50 AM
      Jacksonville, FL
      Downtown Bus Stop
      0
      Greyhound US
      Economy
      $43
    Travel time is the same as the direct connection, but you will save $14

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 15h 50m 5:00 PM Key West, FL Bus Stop 8:50 AM Jacksonville, FL Downtown Bus Stop  Economy $92
  • Did you know that if you travel from Key West, FL to Jacksonville, FL via Miami Airport, you can save more than $27? You can find the corresponding connections below.
    • Greyhound US
      15h 50m
      0
      5:00 PM
      Key West, FL
      Bus Stop
      9:15 PM
      Miami Airport
      Miami Airport - Terminal J
      0
      Greyhound US
      Economy
      $21
      • Waiting Time 2h 10m
    • Greyhound US
      9h 25m
      0
      11:25 PM
      Miami Airport
      Miami Airport - Terminal J
      8:50 AM
      Jacksonville, FL
      Downtown Bus Stop
      0
      Greyhound US
      Economy
      $43
    Travel time is the same as the direct connection, but you will save $27

Cheapest bus trips Thursday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 21h 0m 10:00 AM Key West, FL Bus Stop 7:00 AM Jacksonville, FL Downtown Bus Stop  Economy $77
Greyhound US 14h 45m 5:00 PM Key West, FL Bus Stop 7:45 AM Jacksonville, FL Downtown Bus Stop  Economy $77
  • Did you know that if you travel from Key West, FL to Jacksonville, FL via Miami Airport, you can save more than $12? You can find the corresponding connections below.
    • Greyhound US
      15h 50m
      0
      5:00 PM
      Key West, FL
      Bus Stop
      9:15 PM
      Miami Airport
      Miami Airport - Terminal J
      0
      Greyhound US
      Economy
      $21
      • Waiting Time 2h 10m
    • Greyhound US
      9h 25m
      0
      11:25 PM
      Miami Airport
      Miami Airport - Terminal J
      8:50 AM
      Jacksonville, FL
      Downtown Bus Stop
      0
      Greyhound US
      Economy
      $43
    Travel time is 1h 5m longer, but you will save $12

Cheapest bus trips Friday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 14h 45m 5:00 PM Key West, FL Bus Stop 7:45 AM Jacksonville, FL Amtrak Train Station  Economy $78
Greyhound US 17h 30m 1:30 PM Key West, FL Bus Stop 7:00 AM Jacksonville, FL Amtrak Train Station  Economy $80
  • Did you know that if you travel from Key West, FL to Jacksonville, FL via Miami Airport, you can save more than $13? You can find the corresponding connections below.
    • Greyhound US
      15h 50m
      0
      5:00 PM
      Key West, FL
      Bus Stop
      9:15 PM
      Miami Airport
      Miami Airport - Terminal J
      0
      Greyhound US
      Economy
      $21
      • Waiting Time 2h 10m
    • Greyhound US
      9h 25m
      0
      11:25 PM
      Miami Airport
      Miami Airport - Terminal J
      8:50 AM
      Jacksonville, FL
      Downtown Bus Stop
      0
      Greyhound US
      Economy
      $43
    Travel time is 1h 5m longer, but you will save $13

Cheapest bus trips Saturday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 17h 30m 1:30 PM Key West, FL Bus Stop 7:00 AM Jacksonville, FL Amtrak Train Station  Economy $71
Greyhound US 14h 45m 5:00 PM Key West, FL Bus Stop 7:45 AM Jacksonville, FL Amtrak Train Station  Economy $72

Cheapest bus trips Sunday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 17h 30m 1:30 PM Key West, FL Bus Stop 7:00 AM Jacksonville, FL Downtown Bus Stop  Economy $73
Greyhound US 14h 45m 5:00 PM Key West, FL Bus Stop 7:45 AM Jacksonville, FL Downtown Bus Stop  Economy $76
  • Did you know that if you travel from Key West, FL to Jacksonville, FL via Miami Airport, you can save more than $10? You can find the corresponding connections below.
    • Greyhound US
      22h 0m
      0
      5:00 PM
      Key West, FL
      Bus Stop
      9:15 PM
      Miami Airport
      Miami Airport - Terminal J
      0
      Greyhound US
      Economy
      $23
      • Waiting Time 8h 0m
    • Greyhound US
      9h 45m
      0
      5:15 AM
      Miami Airport
      Miami Airport - Terminal J
      3:00 PM
      Jacksonville, FL
      Downtown Bus Stop
      0
      Greyhound US
      Economy
      $40
    Travel time is 7h 15m longer, but you will save $10

Best Price Offer: The price for the cheapest bus from Key West, FL to Jacksonville, FL is $71 on 5/4/2026. Flexible travelers save on ticket prices.


Frequency of bus connections between Key West, FL and Jacksonville, FL

See here how frequent the connections between Key West, FL and Jacksonville, FL are, during different times and days of the week.
Sunday is the busiest day, with more than 4 daily buses from Key West, FL to Jacksonville, FL. Tuesday has instead the fewest connections, with only 1 daily coaches between Key West, FL and Jacksonville, FL.
The busiest time of the day is the Afternoon, with 14 buses from Key West, FL to Jacksonville, FL, while Morning sees the fewest connections between Key West, FL and Jacksonville, FL, with 1 offers.

Facts about the bus from Key West, FL to Jacksonville, FL

Compare all providers like Greyhound US that travel 2 times every day by bus from Key West, FL to Jacksonville, FL in one click! Book your bus ticket from Key West, FL to Jacksonville, FL starting from $71!

Cheapest Bus $71
Fastest Bus 14h 45m
Earliest Bus 1:30 PM
Latest Bus 5:00 PM
Daily Bus Routes 2 Ø
Distance 399.1 miles
Bus Companies Greyhound US

Cheapest bus connections from Key West, FL to Jacksonville, FL

Every day, 2 buses from 1 bus companies leave Key West, FL for Jacksonville, FL: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 04/27/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 04/26
Monday 04/27
$79
Tuesday 04/28
$92
Wednesday 04/29
Thursday 04/30
$77
Friday 05/01
$78
Saturday 05/02
$71
Sunday 05/03
$76
Monday 05/04
$71
Tuesday 05/05
Wednesday 05/06
Thursday 05/07
Friday 05/08
$79
Saturday 05/09
$75
Sunday 05/10
$75
Monday 05/11
$82
Tuesday 05/12
$87
Wednesday 05/13
$77
Thursday 05/14
$78
Friday 05/15
$77
Saturday 05/16
$76
Sunday 05/17
$79
Monday 05/18
Tuesday 05/19
$78
Wednesday 05/20
Thursday 05/21
$84
Friday 05/22
$90
Saturday 05/23

The cheapest time to travel from Key West, FL to Jacksonville, FL

See here on which day and which time of the day you can find the cheapest bus ticket from Key West, FL to Jacksonville, FL, for the next 30 days.
With a price starting from $71, Monday is the cheapest day for a bus from Key West, FL to Jacksonville, FL. Tuesday instead is the most expensive day with prices starting from $78.
Afternoon is the cheapest day time for bus tickets from Key West, FL to Jacksonville, FL, with $71. Morning is the most expensive time of the day with prices starting from $76.

How to save money travelling from Key West, FL to Jacksonville, FL

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Key West, FL to Jacksonville, FL in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Key West, FL to Jacksonville, FL, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Key West, FL to Jacksonville, FL are also emptier.

Beloved bus companies from Key West, FL to Jacksonville, FL

These are the most booked bus companies between Key West, FL to Jacksonville, FL from our users.

Greyhound US from Key West, FL to Jacksonville, FL

Greyhound US

Here you will find the key facts about the Greyhound US bus route Key West, FL to Jacksonville, FL:

Cheapest Price $71
Fastest Bus 14h 45m
Earliest Bus 1:30 PM
Last Bus 5:00 PM
Daily Connections 2 Ø
Found on 4/2/2026

All bus stations and stops in Key West, FL and Jacksonville, FL

In the map below, you can see where to find all bus stations in Key West, FL and Jacksonville, FL.

Service and Comfort on the bus from Key West, FL to Jacksonville, FL

Want to know which seat classes are available on the buses from Key West, FL to Jacksonville, FL? Or which bus companies serve the route Key West, FL to Jacksonville, FL? Below you will find answers to your questions.

FAQs about the Key West, FL to Jacksonville, FL bus

How much does a Key West, FL Jacksonville, FL bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $71 and takes 17h 30m to reach Jacksonville, FL. Compare offers to save money!

How much could I save by comparing buses from Key West, FL to Jacksonville, FL?

This route is offered by 1 companies with a range of ticket prices between $71 and $92. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Jacksonville, FL.

On average, how many connections are available from Key West, FL to Jacksonville, FL each day?

Every day, the Key West, FL to Jacksonville, FL bus route is served by approximately 2 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Key West, FL to Jacksonville, FL take?

The fastest bus from Key West, FL to Jacksonville, FL is offered by Greyhound US and takes 14h 45m. Bus tickets for this connection cost $77. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Key West, FL to Jacksonville, FL?

The earliest bus arriving in Jacksonville, FL from Key West, FL starts at 1:30 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Key West, FL to Jacksonville, FL?

The latest bus trip departing from Key West, FL for Jacksonville, FL starts at 5:00 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Key West, FL Jacksonville, FL route?

When traveling by bus from Key West, FL to Jacksonville, FL, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Key West, FL and Jacksonville, FL?

You can check all the direct connections between Key West, FL and Jacksonville, FL by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Key West, FL to Jacksonville, FL bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Key West, FL Jacksonville, FL bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Key West, FL Jacksonville, FL bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Key West, FL to Jacksonville, FL on your planned travel date.

How does CheckMyBus find the best bus deals from Key West, FL to Jacksonville, FL?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 2 daily trips between Key West, FL and Jacksonville, FL. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Key West, FL to Jacksonville, FL?

Prices and availability for 2 trips between Key West, FL and Jacksonville, FL change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Key West, FL to Jacksonville, FL

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Key West, FL and to Jacksonville, FL

Here’s an overview of the most popular bus routes to Key West, FL and to Jacksonville, FL. Simply click on the connection of your choice, and you will find all the details about your bus route!
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Bus to Jacksonville, FL from New Brunswick, NJ Bus to Jacksonville, FL from New Brunswick, NJ
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Clarksville, TN to Jacksonville, FL bus Clarksville, TN to Jacksonville, FL bus
Bus Fayetteville, NC - Jacksonville, FL Bus Fayetteville, NC - Jacksonville, FL
Popular Airport Shuttles to Key West, FL and to Jacksonville, FL
CheckMyBus › Buses in USA › Bus to Key West, FL › Bus to Jacksonville, FL

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