Which bus from Opelousas, LA to San Antonio, TX is the cheapest?

Compare all bus companies and find the best price: Bus tickets from $101
The Best Deals Save up to 70%
The Most Choices Millions of routes worldwide
Easy and Transparent Compare offers with 1 click

Compare all timetables for the bus from Opelousas, LA to San Antonio, TX

Here is a selection of the cheapest bus trips from the schedule from Opelousas, LA to San Antonio, TX from various bus operators like Greyhound US for the next days.

today
tomorrow
Friday
Saturday
$101
Sunday
Monday
Tuesday

Cheapest bus trips Saturday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 12h 10m 3:10 AM Opelousas, LA Texaco 167 Truck Stop 3:20 PM San Antonio, TX Bus Station  Economy $101
Greyhound US 13h 50m 11:05 PM Opelousas, LA Texaco 167 Truck Stop 12:55 PM San Antonio, TX Bus Station  Economy $101
Greyhound US 14h 45m 2:15 PM Opelousas, LA Texaco 167 Truck Stop 5:00 AM San Antonio, TX Bus Station  Economy $102
Greyhound US 12h 55m 4:30 PM Opelousas, LA Texaco 167 Truck Stop 5:25 AM San Antonio, TX Bus Station  Economy $102
  • Did you know that if you travel from Opelousas, LA to San Antonio, TX via Houston, you can save more than $32? You can find the corresponding connections below.
    • FlixBus
      12h 55m
      0
      4:30 PM
      Opelousas, LA
      Texaco 167 Truck Stop
      1:25 AM
      Houston
      Harrisburg Blvd Station
      0
      FlixBus
      Economy
      $43
      • Waiting Time 0h 35m
    • Busbud
      3h 25m
      0
      2:00 AM
      Houston
      Harrisburg Blvd Station
      5:25 AM
      San Antonio, TX
      Bus Station
      0
      Busbud
      Economy
      $26
    Travel time is 0h 45m longer, but you will save $32

Best Price Offer: The price for the cheapest bus from Opelousas, LA to San Antonio, TX is $101 on 2/14/2026. Flexible travelers save on ticket prices.


Facts about the bus from Opelousas, LA to San Antonio, TX

Compare all providers like Greyhound US that travel 4 times every day by bus from Opelousas, LA to San Antonio, TX in one click! Book your bus ticket from Opelousas, LA to San Antonio, TX starting from $101!

Cheapest Bus $101
Fastest Bus 12h 10m
Earliest Bus 3:10 AM
Latest Bus 11:05 PM
Daily Bus Routes 4 Ø
Distance 390.9 miles
Bus Companies Greyhound US

Cheapest bus connections from Opelousas, LA to San Antonio, TX

Every day, 4 buses from 1 bus companies leave Opelousas, LA for San Antonio, TX: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 02/11/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 02/08
Monday 02/09
Tuesday 02/10
Wednesday 02/11
Thursday 02/12
Friday 02/13
Saturday 02/14
$101
Sunday 02/15
Monday 02/16
Tuesday 02/17
Wednesday 02/18
Thursday 02/19
Friday 02/20
Saturday 02/21
Sunday 02/22
Monday 02/23
Tuesday 02/24
Wednesday 02/25
Thursday 02/26
Friday 02/27
Saturday 02/28
Sunday 03/01
Monday 03/02
Tuesday 03/03
Wednesday 03/04
Thursday 03/05
Friday 03/06
Saturday 03/07

How to save money travelling from Opelousas, LA to San Antonio, TX

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Opelousas, LA to San Antonio, TX in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Opelousas, LA to San Antonio, TX, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Opelousas, LA to San Antonio, TX are also emptier.

All bus stations and stops in Opelousas, LA and San Antonio, TX

In the map below, you can see where to find all bus stations in Opelousas, LA and San Antonio, TX.

Service and Comfort on the bus from Opelousas, LA to San Antonio, TX

Want to know which seat classes are available on the buses from Opelousas, LA to San Antonio, TX? Or which bus companies serve the route Opelousas, LA to San Antonio, TX? Below you will find answers to your questions.

FAQs about the Opelousas, LA to San Antonio, TX bus

How much does a Opelousas, LA San Antonio, TX bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $101 and takes 12h 10m to reach San Antonio, TX. Compare offers to save money!

How much could I save by comparing buses from Opelousas, LA to San Antonio, TX?

This route is offered by 1 companies with a range of ticket prices between $101 and $102. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to San Antonio, TX.

On average, how many connections are available from Opelousas, LA to San Antonio, TX each day?

Every day, the Opelousas, LA to San Antonio, TX bus route is served by approximately 4 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Opelousas, LA to San Antonio, TX take?

The fastest bus from Opelousas, LA to San Antonio, TX is offered by Greyhound US and takes 12h 10m. Bus tickets for this connection cost $101. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Opelousas, LA to San Antonio, TX?

The earliest bus arriving in San Antonio, TX from Opelousas, LA starts at 3:10 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Opelousas, LA to San Antonio, TX?

The latest bus trip departing from Opelousas, LA for San Antonio, TX starts at 11:05 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Opelousas, LA San Antonio, TX route?

When traveling by bus from Opelousas, LA to San Antonio, TX, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Opelousas, LA and San Antonio, TX?

You can check all the direct connections between Opelousas, LA and San Antonio, TX by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Opelousas, LA to San Antonio, TX bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Opelousas, LA San Antonio, TX bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Opelousas, LA San Antonio, TX bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Opelousas, LA to San Antonio, TX on your planned travel date.

How does CheckMyBus find the best bus deals from Opelousas, LA to San Antonio, TX?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 4 daily trips between Opelousas, LA and San Antonio, TX. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Opelousas, LA to San Antonio, TX?

Prices and availability for 4 trips between Opelousas, LA and San Antonio, TX change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Opelousas, LA to San Antonio, TX

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Opelousas, LA and to San Antonio, TX

Here’s an overview of the most popular bus routes to Opelousas, LA and to San Antonio, TX. Simply click on the connection of your choice, and you will find all the details about your bus route!
Buses Dallas - Opelousas, LA Buses Dallas - Opelousas, LA
Bus to Opelousas, LA from Beaumont, TX Bus to Opelousas, LA from Beaumont, TX
Buses to Opelousas, LA from Shreveport, LA Buses to Opelousas, LA from Shreveport, LA
From Houston to Opelousas, LA bus From Houston to Opelousas, LA bus
Buses from Matehuala to San Antonio, TX Buses from Matehuala to San Antonio, TX
Bus College Station, TX to San Antonio, TX Bus College Station, TX to San Antonio, TX
Bus Abilene, TX to San Antonio, TX Bus Abilene, TX to San Antonio, TX
Buses from Lubbock, TX to San Antonio, TX Buses from Lubbock, TX to San Antonio, TX
Popular Airport Shuttles to Opelousas, LA and to San Antonio, TX
CheckMyBus › Buses in USA › Bus to Opelousas, LA › Bus to San Antonio, TX

The CheckMyBus App

Free Download

App Store
CheckMyBus App
Close
GPDR CheckMyBus shield

We value your privacy!

To

show

you

the

best

bus

offers,

we

and

our

partners

use

technical,

analytical,

and

marketing

cookies

to

personalize

the

ads.

We

remember

your

anonymized

details

to

provide

a

personalized

experience.