Bus from Salisbury, NC to Buffalo, NY from $116

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Compare all timetables for the bus from Salisbury, NC to Buffalo, NY

Here is a selection of the cheapest bus trips from the schedule from Salisbury, NC to Buffalo, NY from various bus operators like Greyhound US for the next days.

today
$122
tomorrow
$122
Saturday
$118
Sunday
Monday
$118
Tuesday
$118
Wednesday
$118

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 27h 55m 11:10 AM Salisbury, NC Greyhound bus station 3:05 PM Buffalo, NY Central Bus Station  Economy $122
Greyhound US 24h 5m 6:45 PM Salisbury, NC Greyhound bus station 6:50 PM Buffalo, NY Central Bus Station  Economy $123
Greyhound US 25h 15m 6:15 AM Salisbury, NC Greyhound bus station 7:30 AM Buffalo, NY Central Bus Station  Economy $125
  • Did you know that if you travel from Salisbury, NC to Buffalo, NY via Charlotte, you can save more than $18? You can find the corresponding connections below.
    • Greyhound US
      24h 5m
      0
      6:45 PM
      Salisbury, NC
      Greyhound bus station
      7:40 PM
      Charlotte
      W Trade St
      0
      Greyhound US
      Economy
      $12
      • Waiting Time 1h 45m
    • Greyhound US
      21h 25m
      0
      9:25 PM
      Charlotte
      W Trade St
      6:50 PM
      Buffalo, NY
      Central Bus Station
      0
      Greyhound US
      Economy
      $92
    Travel time is the same as the direct connection, but you will save $18

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 25h 15m 6:15 AM Salisbury, NC Greyhound bus station 7:30 AM Buffalo, NY Central Bus Station  Economy $122
Greyhound US 24h 5m 6:45 PM Salisbury, NC Greyhound bus station 6:50 PM Buffalo, NY Central Bus Station  Economy $123
Greyhound US 27h 55m 11:10 AM Salisbury, NC Greyhound bus station 3:05 PM Buffalo, NY Central Bus Station  Economy $146
  • Did you know that if you travel from Salisbury, NC to Buffalo, NY via Charlotte, you can save more than $18? You can find the corresponding connections below.
    • Greyhound US
      24h 5m
      0
      6:45 PM
      Salisbury, NC
      Greyhound bus station
      7:40 PM
      Charlotte
      W Trade St
      0
      Greyhound US
      Economy
      $12
      • Waiting Time 1h 45m
    • Greyhound US
      21h 25m
      0
      9:25 PM
      Charlotte
      W Trade St
      6:50 PM
      Buffalo, NY
      Central Bus Station
      0
      Greyhound US
      Economy
      $92
    Travel time is the same as the direct connection, but you will save $18

Cheapest bus trips Saturday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 27h 55m 11:10 AM Salisbury, NC Greyhound bus station 3:05 PM Buffalo, NY Central Bus Station  Economy $118
Greyhound US 24h 5m 6:45 PM Salisbury, NC Greyhound bus station 6:50 PM Buffalo, NY Central Bus Station  Economy $119
Greyhound US 25h 15m 6:15 AM Salisbury, NC Greyhound bus station 7:30 AM Buffalo, NY Central Bus Station  Economy $125
  • Did you know that if you travel from Salisbury, NC to Buffalo, NY via Charlotte, you can save more than $14? You can find the corresponding connections below.
    • Greyhound US
      24h 5m
      0
      6:45 PM
      Salisbury, NC
      Greyhound bus station
      7:40 PM
      Charlotte
      W Trade St
      0
      Greyhound US
      Economy
      $12
      • Waiting Time 1h 45m
    • Greyhound US
      21h 25m
      0
      9:25 PM
      Charlotte
      W Trade St
      6:50 PM
      Buffalo, NY
      Central Bus Station
      0
      Greyhound US
      Economy
      $92
    Travel time is the same as the direct connection, but you will save $14

Cheapest bus trips Monday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 27h 55m 11:10 AM Salisbury, NC Greyhound bus station 3:05 PM Buffalo, NY Central Bus Station  Economy $118
Greyhound US 24h 5m 6:45 PM Salisbury, NC Greyhound bus station 6:50 PM Buffalo, NY Central Bus Station  Economy $119
Greyhound US 25h 15m 6:15 AM Salisbury, NC Greyhound bus station 7:30 AM Buffalo, NY Central Bus Station  Economy $121
  • Did you know that if you travel from Salisbury, NC to Buffalo, NY via Charlotte, you can save more than $20? You can find the corresponding connections below.
    • Greyhound US
      29h 50m
      0
      11:10 AM
      Salisbury, NC
      Greyhound bus station
      11:55 AM
      Charlotte
      W Trade St
      0
      Greyhound US
      Economy
      $12
      • Waiting Time 6h 10m
    • Greyhound US
      22h 55m
      0
      6:05 PM
      Charlotte
      W Trade St
      5:00 PM
      Buffalo, NY
      Central Bus Station
      0
      Greyhound US
      Economy
      $86
    Travel time is 5h 45m longer, but you will save $20

Cheapest bus trips Tuesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 27h 55m 11:10 AM Salisbury, NC Greyhound bus station 3:05 PM Buffalo, NY Central Bus Station  Economy $118
Greyhound US 24h 5m 6:45 PM Salisbury, NC Greyhound bus station 6:50 PM Buffalo, NY Central Bus Station  Economy $119
Greyhound US 25h 15m 6:15 AM Salisbury, NC Greyhound bus station 7:30 AM Buffalo, NY Central Bus Station  Economy $130
  • Did you know that if you travel from Salisbury, NC to Buffalo, NY via Charlotte, you can save more than $20? You can find the corresponding connections below.
    • Greyhound US
      29h 50m
      0
      11:10 AM
      Salisbury, NC
      Greyhound bus station
      11:55 AM
      Charlotte
      W Trade St
      0
      Greyhound US
      Economy
      $12
      • Waiting Time 6h 10m
    • Greyhound US
      22h 55m
      0
      6:05 PM
      Charlotte
      W Trade St
      5:00 PM
      Buffalo, NY
      Central Bus Station
      0
      Greyhound US
      Economy
      $86
    Travel time is 5h 45m longer, but you will save $20

Cheapest bus trips Wednesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 27h 55m 11:10 AM Salisbury, NC Greyhound bus station 3:05 PM Buffalo, NY Central Bus Station  Economy $118
Greyhound US 24h 5m 6:45 PM Salisbury, NC Greyhound bus station 6:50 PM Buffalo, NY Central Bus Station  Economy $119
Greyhound US 25h 15m 6:15 AM Salisbury, NC Greyhound bus station 7:30 AM Buffalo, NY Central Bus Station  Economy $121
  • Did you know that if you travel from Salisbury, NC to Buffalo, NY via Charlotte, you can save more than $20? You can find the corresponding connections below.
    • Greyhound US
      29h 50m
      0
      11:10 AM
      Salisbury, NC
      Greyhound bus station
      11:55 AM
      Charlotte
      W Trade St
      0
      Greyhound US
      Economy
      $12
      • Waiting Time 6h 10m
    • Greyhound US
      22h 55m
      0
      6:05 PM
      Charlotte
      W Trade St
      5:00 PM
      Buffalo, NY
      Central Bus Station
      0
      Greyhound US
      Economy
      $86
    Travel time is 5h 45m longer, but you will save $20

Best Price Offer: The price for the cheapest bus from Salisbury, NC to Buffalo, NY is $116 on 6/16/2026. Flexible travelers save on ticket prices.


Frequency of bus connections between Salisbury, NC and Buffalo, NY

See here how frequent the connections between Salisbury, NC and Buffalo, NY are, during different times and days of the week.
Wednesday is the busiest day, with more than 6 daily buses from Salisbury, NC to Buffalo, NY. Monday has instead the fewest connections, with only 3 daily coaches between Salisbury, NC and Buffalo, NY.
The busiest time of the day is the Morning, with 16 buses from Salisbury, NC to Buffalo, NY, while Evening sees the fewest connections between Salisbury, NC and Buffalo, NY, with 8 offers.

Facts about the bus from Salisbury, NC to Buffalo, NY

Compare all providers like Greyhound US that travel 4 times every day by bus from Salisbury, NC to Buffalo, NY in one click! Book your bus ticket from Salisbury, NC to Buffalo, NY starting from $116!

Cheapest Bus $116
Fastest Bus 24h 5m
Earliest Bus 6:15 AM
Latest Bus 6:45 PM
Daily Bus Routes 4 Ø
Distance 505.7 miles
Bus Companies Greyhound US

Cheapest bus connections from Salisbury, NC to Buffalo, NY

Every day, 4 buses from 1 bus companies leave Salisbury, NC for Buffalo, NY: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 06/04/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 05/31
Monday 06/01
Tuesday 06/02
Wednesday 06/03
Thursday 06/04
$122
Friday 06/05
$122
Saturday 06/06
$118
Sunday 06/07
Monday 06/08
$118
Tuesday 06/09
$118
Wednesday 06/10
$118
Thursday 06/11
$119
Friday 06/12
$123
Saturday 06/13
$118
Sunday 06/14
$118
Monday 06/15
Tuesday 06/16
$116
Wednesday 06/17
$116
Thursday 06/18
$122
Friday 06/19
$118
Saturday 06/20
$120
Sunday 06/21
$118
Monday 06/22
$122
Tuesday 06/23
$116
Wednesday 06/24
$122
Thursday 06/25
Friday 06/26
Saturday 06/27

The cheapest time to travel from Salisbury, NC to Buffalo, NY

See here on which day and which time of the day you can find the cheapest bus ticket from Salisbury, NC to Buffalo, NY, for the next 30 days.
With a price starting from $116, Tuesday is the cheapest day for a bus from Salisbury, NC to Buffalo, NY. Thursday instead is the most expensive day with prices starting from $119.
Morning is the cheapest day time for bus tickets from Salisbury, NC to Buffalo, NY, with $118. Evening is the most expensive time of the day with prices starting from $119.

How to save money travelling from Salisbury, NC to Buffalo, NY

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Salisbury, NC to Buffalo, NY in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Salisbury, NC to Buffalo, NY, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Salisbury, NC to Buffalo, NY are also emptier.

Beloved bus companies from Salisbury, NC to Buffalo, NY

These are the most booked bus companies between Salisbury, NC to Buffalo, NY from our users.

Greyhound US from Salisbury, NC to Buffalo, NY

Greyhound US

Here you will find the key facts about the Greyhound US bus route Salisbury, NC to Buffalo, NY:

Cheapest Price $118
Fastest Bus 24h 5m
Earliest Bus 6:15 AM
Last Bus 6:45 PM
Daily Connections 4 Ø
Found on 5/11/2026

All bus stations and stops in Salisbury, NC and Buffalo, NY

In the map below, you can see where to find all bus stations in Salisbury, NC and Buffalo, NY.

Service and Comfort on the bus from Salisbury, NC to Buffalo, NY

Want to know which seat classes are available on the buses from Salisbury, NC to Buffalo, NY? Or which bus companies serve the route Salisbury, NC to Buffalo, NY? Below you will find answers to your questions.

FAQs about the Salisbury, NC to Buffalo, NY bus

How much does a Salisbury, NC Buffalo, NY bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $116 and takes 27h 55m to reach Buffalo, NY. Compare offers to save money!

How much could I save by comparing buses from Salisbury, NC to Buffalo, NY?

This route is offered by 1 companies with a range of ticket prices between $116 and $146. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Buffalo, NY.

On average, how many connections are available from Salisbury, NC to Buffalo, NY each day?

Every day, the Salisbury, NC to Buffalo, NY bus route is served by approximately 4 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Salisbury, NC to Buffalo, NY take?

The fastest bus from Salisbury, NC to Buffalo, NY is offered by Greyhound US and takes 24h 5m. Bus tickets for this connection cost $123. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Salisbury, NC to Buffalo, NY?

The earliest bus arriving in Buffalo, NY from Salisbury, NC starts at 6:15 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Salisbury, NC to Buffalo, NY?

The latest bus trip departing from Salisbury, NC for Buffalo, NY starts at 6:45 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Salisbury, NC Buffalo, NY route?

When traveling by bus from Salisbury, NC to Buffalo, NY, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Salisbury, NC and Buffalo, NY?

You can check all the direct connections between Salisbury, NC and Buffalo, NY by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Salisbury, NC to Buffalo, NY bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Salisbury, NC Buffalo, NY bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Salisbury, NC Buffalo, NY bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Salisbury, NC to Buffalo, NY on your planned travel date.

How does CheckMyBus find the best bus deals from Salisbury, NC to Buffalo, NY?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 4 daily trips between Salisbury, NC and Buffalo, NY. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Salisbury, NC to Buffalo, NY?

Prices and availability for 4 trips between Salisbury, NC and Buffalo, NY change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Salisbury, NC to Buffalo, NY

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Salisbury, NC and to Buffalo, NY

Here’s an overview of the most popular bus routes to Salisbury, NC and to Buffalo, NY. Simply click on the connection of your choice, and you will find all the details about your bus route!
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Popular Airport Shuttles to Salisbury, NC and to Buffalo, NY
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