What is the best way to travel from Cincinnati to Knoxville, TN?
Looking for a trip? Compare all the available Buses and Flights for the journey to Knoxville, TN from Cincinnati. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 1 available companies to find your perfect trip!
What is the cheapest way to reach Knoxville, TN from Cincinnati?
You can get to Knoxville, TN with just $41 by taking a Bus from Greyhound US, but you can find many more cheap offers: we have selected the best ones for next few days here for you.
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Frontier Airlines11h 55m09:49 AMCincinnati/Northern Kentucky AirportCincinnati/Northern Kentucky Airport9:44 PMKnoxville AirportKnoxville Airport0EconomyA Flight from Frontier Airlines goes from Cincinnati/Northern Kentucky Airport, Cincinnati/Northern Kentucky Airport (USA) at 12/14/2025 9:49:00 AM to Knoxville Airport, Knoxville Airport (USA) arriving at 12/14/2025 9:44:00 PM. 50 Economy ticket for $143 per person are available. Travel duration is 11h 55m
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Frontier Airlines11h 28m05:05 AMCincinnati/Northern Kentucky AirportCincinnati/Northern Kentucky Airport4:33 PMKnoxville AirportKnoxville Airport0EconomyA Flight from Frontier Airlines goes from Cincinnati/Northern Kentucky Airport, Cincinnati/Northern Kentucky Airport (USA) at 12/14/2025 5:05:00 AM to Knoxville Airport, Knoxville Airport (USA) arriving at 12/14/2025 4:33:00 PM. 50 Economy ticket for $147 per person are available. Travel duration is 11h 28m
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Skyscanner4h 48m06:00 AMCincinnati/Northern Kentucky AirportCincinnati/Northern Kentucky Airport10:48 AMKnoxville AirportKnoxville Airport0EconomyA Flight from Skyscanner goes from Cincinnati/Northern Kentucky Airport, Cincinnati/Northern Kentucky Airport (USA) at 12/14/2025 6:00:00 AM to Knoxville Airport, Knoxville Airport (USA) arriving at 12/14/2025 10:48:00 AM. 50 Economy ticket for $273 per person are available. Travel duration is 4h 48m
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Skyscanner4h 17m09:00 AMCincinnati/Northern Kentucky AirportCincinnati/Northern Kentucky Airport1:17 PMKnoxville AirportKnoxville Airport0EconomyA Flight from Skyscanner goes from Cincinnati/Northern Kentucky Airport, Cincinnati/Northern Kentucky Airport (USA) at 12/14/2025 9:00:00 AM to Knoxville Airport, Knoxville Airport (USA) arriving at 12/14/2025 1:17:00 PM. 50 Economy ticket for $273 per person are available. Travel duration is 4h 17m
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United Airlines6h 17m07:00 AMCincinnati/Northern Kentucky AirportCincinnati/Northern Kentucky Airport1:17 PMKnoxville AirportKnoxville Airport0EconomyA Flight from United Airlines goes from Cincinnati/Northern Kentucky Airport, Cincinnati/Northern Kentucky Airport (USA) at 12/14/2025 7:00:00 AM to Knoxville Airport, Knoxville Airport (USA) arriving at 12/14/2025 1:17:00 PM. 50 Economy ticket for $273 per person are available. Travel duration is 6h 17m
Cheapest Flights Sunday
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Greyhound US5h 35m01:20 PMCincinnatiGreyhound Bus Station6:55 PMKnoxville, TNGreyhound Bus Station0EconomyA Bus from Greyhound US goes from Greyhound Bus Station, Cincinnati (USA) at 12/15/2025 1:20:00 PM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 12/15/2025 6:55:00 PM. 50 Economy ticket for $41 per person are available. Travel duration is 5h 35m
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Frontier Airlines28h 5m011:57 AMCincinnati/Northern Kentucky AirportCincinnati/Northern Kentucky Airport4:02 PMKnoxville AirportKnoxville Airport0EconomyA Flight from Frontier Airlines goes from Cincinnati/Northern Kentucky Airport, Cincinnati/Northern Kentucky Airport (USA) at 12/15/2025 11:57:00 AM to Knoxville Airport, Knoxville Airport (USA) arriving at 12/16/2025 4:02:00 PM. 50 Economy ticket for $100 per person are available. Travel duration is 28h 5m
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Frontier Airlines19h 7m08:55 PMCincinnati/Northern Kentucky AirportCincinnati/Northern Kentucky Airport4:02 PMKnoxville AirportKnoxville Airport0EconomyA Flight from Frontier Airlines goes from Cincinnati/Northern Kentucky Airport, Cincinnati/Northern Kentucky Airport (USA) at 12/15/2025 8:55:00 PM to Knoxville Airport, Knoxville Airport (USA) arriving at 12/16/2025 4:02:00 PM. 50 Economy ticket for $100 per person are available. Travel duration is 19h 7m
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Allegiant Air10h 44m08:30 AMCincinnati/Northern Kentucky AirportCincinnati/Northern Kentucky Airport7:14 PMKnoxville AirportKnoxville Airport0EconomyA Flight from Allegiant Air goes from Cincinnati/Northern Kentucky Airport, Cincinnati/Northern Kentucky Airport (USA) at 12/15/2025 8:30:00 AM to Knoxville Airport, Knoxville Airport (USA) arriving at 12/15/2025 7:14:00 PM. 50 Economy ticket for $145 per person are available. Travel duration is 10h 44m
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Skyscanner4h 48m06:00 AMCincinnati/Northern Kentucky AirportCincinnati/Northern Kentucky Airport10:48 AMKnoxville AirportKnoxville Airport0EconomyA Flight from Skyscanner goes from Cincinnati/Northern Kentucky Airport, Cincinnati/Northern Kentucky Airport (USA) at 12/15/2025 6:00:00 AM to Knoxville Airport, Knoxville Airport (USA) arriving at 12/15/2025 10:48:00 AM. 50 Economy ticket for $274 per person are available. Travel duration is 4h 48m
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Skyscanner4h 17m09:00 AMCincinnati/Northern Kentucky AirportCincinnati/Northern Kentucky Airport1:17 PMKnoxville AirportKnoxville Airport0EconomyA Flight from Skyscanner goes from Cincinnati/Northern Kentucky Airport, Cincinnati/Northern Kentucky Airport (USA) at 12/15/2025 9:00:00 AM to Knoxville Airport, Knoxville Airport (USA) arriving at 12/15/2025 1:17:00 PM. 50 Economy ticket for $274 per person are available. Travel duration is 4h 17m
Cheapest Buses Monday
Cheapest Flights Monday
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Greyhound US5h 35m01:20 PMCincinnatiGreyhound Bus Station6:55 PMKnoxville, TNGreyhound Bus Station0EconomyA Bus from Greyhound US goes from Greyhound Bus Station, Cincinnati (USA) at 12/16/2025 1:20:00 PM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 12/16/2025 6:55:00 PM. 50 Economy ticket for $44 per person are available. Travel duration is 5h 35m
Cheapest Buses Tuesday
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Greyhound US5h 35m01:20 PMCincinnatiGreyhound Bus Station6:55 PMKnoxville, TNGreyhound Bus Station0EconomyA Bus from Greyhound US goes from Greyhound Bus Station, Cincinnati (USA) at 12/18/2025 1:20:00 PM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 12/18/2025 6:55:00 PM. 50 Economy ticket for $44 per person are available. Travel duration is 5h 35m
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Allegiant Air15h 42m07:00 AMCincinnati/Northern Kentucky AirportCincinnati/Northern Kentucky Airport10:42 PMKnoxville AirportKnoxville Airport0EconomyA Flight from Allegiant Air goes from Cincinnati/Northern Kentucky Airport, Cincinnati/Northern Kentucky Airport (USA) at 12/18/2025 7:00:00 AM to Knoxville Airport, Knoxville Airport (USA) arriving at 12/18/2025 10:42:00 PM. 50 Economy ticket for $113 per person are available. Travel duration is 15h 42m
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Frontier Airlines9h 57m011:57 AMCincinnati/Northern Kentucky AirportCincinnati/Northern Kentucky Airport9:54 PMKnoxville AirportKnoxville Airport0EconomyA Flight from Frontier Airlines goes from Cincinnati/Northern Kentucky Airport, Cincinnati/Northern Kentucky Airport (USA) at 12/18/2025 11:57:00 AM to Knoxville Airport, Knoxville Airport (USA) arriving at 12/18/2025 9:54:00 PM. 50 Economy ticket for $168 per person are available. Travel duration is 9h 57m
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Allegiant Air13h 13m09:19 PMCincinnati/Northern Kentucky AirportCincinnati/Northern Kentucky Airport10:32 AMKnoxville AirportKnoxville Airport0EconomyA Flight from Allegiant Air goes from Cincinnati/Northern Kentucky Airport, Cincinnati/Northern Kentucky Airport (USA) at 12/18/2025 9:19:00 PM to Knoxville Airport, Knoxville Airport (USA) arriving at 12/19/2025 10:32:00 AM. 50 Economy ticket for $194 per person are available. Travel duration is 13h 13m
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Skyscanner4h 56m06:00 AMCincinnati/Northern Kentucky AirportCincinnati/Northern Kentucky Airport10:56 AMKnoxville AirportKnoxville Airport0EconomyA Flight from Skyscanner goes from Cincinnati/Northern Kentucky Airport, Cincinnati/Northern Kentucky Airport (USA) at 12/18/2025 6:00:00 AM to Knoxville Airport, Knoxville Airport (USA) arriving at 12/18/2025 10:56:00 AM. 50 Economy ticket for $274 per person are available. Travel duration is 4h 56m
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Skyscanner4h 28m010:20 AMCincinnati/Northern Kentucky AirportCincinnati/Northern Kentucky Airport2:48 PMKnoxville AirportKnoxville Airport0EconomyA Flight from Skyscanner goes from Cincinnati/Northern Kentucky Airport, Cincinnati/Northern Kentucky Airport (USA) at 12/18/2025 10:20:00 AM to Knoxville Airport, Knoxville Airport (USA) arriving at 12/18/2025 2:48:00 PM. 50 Economy ticket for $274 per person are available. Travel duration is 4h 28m
Cheapest Buses Thursday
Cheapest Flights Thursday
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Greyhound US5h 35m01:20 PMCincinnatiGreyhound Bus Station6:55 PMKnoxville, TNGreyhound Bus Station0EconomyA Bus from Greyhound US goes from Greyhound Bus Station, Cincinnati (USA) at 12/19/2025 1:20:00 PM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 12/19/2025 6:55:00 PM. 50 Economy ticket for $50 per person are available. Travel duration is 5h 35m
Cheapest Buses Friday
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Frontier Airlines15h 34m06:00 AMCincinnati/Northern Kentucky AirportCincinnati/Northern Kentucky Airport9:34 PMKnoxville AirportKnoxville Airport0EconomyA Flight from Frontier Airlines goes from Cincinnati/Northern Kentucky Airport, Cincinnati/Northern Kentucky Airport (USA) at 12/20/2025 6:00:00 AM to Knoxville Airport, Knoxville Airport (USA) arriving at 12/20/2025 9:34:00 PM. 50 Economy ticket for $140 per person are available. Travel duration is 15h 34m
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Frontier Airlines10h 33m06:00 AMCincinnati/Northern Kentucky AirportCincinnati/Northern Kentucky Airport4:33 PMKnoxville AirportKnoxville Airport0EconomyA Flight from Frontier Airlines goes from Cincinnati/Northern Kentucky Airport, Cincinnati/Northern Kentucky Airport (USA) at 12/20/2025 6:00:00 AM to Knoxville Airport, Knoxville Airport (USA) arriving at 12/20/2025 4:33:00 PM. 50 Economy ticket for $159 per person are available. Travel duration is 10h 33m
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Allegiant Air26h 51m06:15 PMCincinnati/Northern Kentucky AirportCincinnati/Northern Kentucky Airport9:06 PMKnoxville AirportKnoxville Airport0EconomyA Flight from Allegiant Air goes from Cincinnati/Northern Kentucky Airport, Cincinnati/Northern Kentucky Airport (USA) at 12/20/2025 6:15:00 PM to Knoxville Airport, Knoxville Airport (USA) arriving at 12/21/2025 9:06:00 PM. 50 Economy ticket for $160 per person are available. Travel duration is 26h 51m
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Allegiant Air9h 13m012:21 PMCincinnati/Northern Kentucky AirportCincinnati/Northern Kentucky Airport9:34 PMKnoxville AirportKnoxville Airport0EconomyA Flight from Allegiant Air goes from Cincinnati/Northern Kentucky Airport, Cincinnati/Northern Kentucky Airport (USA) at 12/20/2025 12:21:00 PM to Knoxville Airport, Knoxville Airport (USA) arriving at 12/20/2025 9:34:00 PM. 50 Economy ticket for $165 per person are available. Travel duration is 9h 13m
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Skyscanner4h 54m05:45 PMCincinnati/Northern Kentucky AirportCincinnati/Northern Kentucky Airport10:39 PMKnoxville AirportKnoxville Airport0EconomyA Flight from Skyscanner goes from Cincinnati/Northern Kentucky Airport, Cincinnati/Northern Kentucky Airport (USA) at 12/20/2025 5:45:00 PM to Knoxville Airport, Knoxville Airport (USA) arriving at 12/20/2025 10:39:00 PM. 50 Economy ticket for $272 per person are available. Travel duration is 4h 54m
Cheapest Flights Saturday
What are the fastest trips from Cincinnati to Knoxville, TN?
You can get to Knoxville, TN from Cincinnati in just 4h 17m with a Flight from Skyscanner. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.
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Skyscanner4h 17m09:00 AMCincinnati/Northern Kentucky AirportCincinnati/Northern Kentucky Airport1:17 PMKnoxville AirportKnoxville Airport0EconomyA Flight from Skyscanner goes from Cincinnati/Northern Kentucky Airport, Cincinnati/Northern Kentucky Airport (USA) at 12/14/2025 9:00:00 AM to Knoxville Airport, Knoxville Airport (USA) arriving at 12/14/2025 1:17:00 PM. 50 Economy ticket for $273 per person are available. Travel duration is 4h 17m
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Skyscanner4h 48m06:00 AMCincinnati/Northern Kentucky AirportCincinnati/Northern Kentucky Airport10:48 AMKnoxville AirportKnoxville Airport0EconomyA Flight from Skyscanner goes from Cincinnati/Northern Kentucky Airport, Cincinnati/Northern Kentucky Airport (USA) at 12/14/2025 6:00:00 AM to Knoxville Airport, Knoxville Airport (USA) arriving at 12/14/2025 10:48:00 AM. 50 Economy ticket for $273 per person are available. Travel duration is 4h 48m
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United Airlines6h 17m07:00 AMCincinnati/Northern Kentucky AirportCincinnati/Northern Kentucky Airport1:17 PMKnoxville AirportKnoxville Airport0EconomyA Flight from United Airlines goes from Cincinnati/Northern Kentucky Airport, Cincinnati/Northern Kentucky Airport (USA) at 12/14/2025 7:00:00 AM to Knoxville Airport, Knoxville Airport (USA) arriving at 12/14/2025 1:17:00 PM. 50 Economy ticket for $273 per person are available. Travel duration is 6h 17m
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Frontier Airlines11h 28m05:05 AMCincinnati/Northern Kentucky AirportCincinnati/Northern Kentucky Airport4:33 PMKnoxville AirportKnoxville Airport0EconomyA Flight from Frontier Airlines goes from Cincinnati/Northern Kentucky Airport, Cincinnati/Northern Kentucky Airport (USA) at 12/14/2025 5:05:00 AM to Knoxville Airport, Knoxville Airport (USA) arriving at 12/14/2025 4:33:00 PM. 50 Economy ticket for $147 per person are available. Travel duration is 11h 28m
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Frontier Airlines11h 55m09:49 AMCincinnati/Northern Kentucky AirportCincinnati/Northern Kentucky Airport9:44 PMKnoxville AirportKnoxville Airport0EconomyA Flight from Frontier Airlines goes from Cincinnati/Northern Kentucky Airport, Cincinnati/Northern Kentucky Airport (USA) at 12/14/2025 9:49:00 AM to Knoxville Airport, Knoxville Airport (USA) arriving at 12/14/2025 9:44:00 PM. 50 Economy ticket for $143 per person are available. Travel duration is 11h 55m
Fastest Flights Sunday
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Skyscanner4h 17m09:00 AMCincinnati/Northern Kentucky AirportCincinnati/Northern Kentucky Airport1:17 PMKnoxville AirportKnoxville Airport0EconomyA Flight from Skyscanner goes from Cincinnati/Northern Kentucky Airport, Cincinnati/Northern Kentucky Airport (USA) at 12/15/2025 9:00:00 AM to Knoxville Airport, Knoxville Airport (USA) arriving at 12/15/2025 1:17:00 PM. 50 Economy ticket for $274 per person are available. Travel duration is 4h 17m
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Skyscanner4h 48m06:00 AMCincinnati/Northern Kentucky AirportCincinnati/Northern Kentucky Airport10:48 AMKnoxville AirportKnoxville Airport0EconomyA Flight from Skyscanner goes from Cincinnati/Northern Kentucky Airport, Cincinnati/Northern Kentucky Airport (USA) at 12/15/2025 6:00:00 AM to Knoxville Airport, Knoxville Airport (USA) arriving at 12/15/2025 10:48:00 AM. 50 Economy ticket for $274 per person are available. Travel duration is 4h 48m
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Allegiant Air10h 44m08:30 AMCincinnati/Northern Kentucky AirportCincinnati/Northern Kentucky Airport7:14 PMKnoxville AirportKnoxville Airport0EconomyA Flight from Allegiant Air goes from Cincinnati/Northern Kentucky Airport, Cincinnati/Northern Kentucky Airport (USA) at 12/15/2025 8:30:00 AM to Knoxville Airport, Knoxville Airport (USA) arriving at 12/15/2025 7:14:00 PM. 50 Economy ticket for $145 per person are available. Travel duration is 10h 44m
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Frontier Airlines19h 7m08:55 PMCincinnati/Northern Kentucky AirportCincinnati/Northern Kentucky Airport4:02 PMKnoxville AirportKnoxville Airport0EconomyA Flight from Frontier Airlines goes from Cincinnati/Northern Kentucky Airport, Cincinnati/Northern Kentucky Airport (USA) at 12/15/2025 8:55:00 PM to Knoxville Airport, Knoxville Airport (USA) arriving at 12/16/2025 4:02:00 PM. 50 Economy ticket for $100 per person are available. Travel duration is 19h 7m
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Frontier Airlines28h 5m011:57 AMCincinnati/Northern Kentucky AirportCincinnati/Northern Kentucky Airport4:02 PMKnoxville AirportKnoxville Airport0EconomyA Flight from Frontier Airlines goes from Cincinnati/Northern Kentucky Airport, Cincinnati/Northern Kentucky Airport (USA) at 12/15/2025 11:57:00 AM to Knoxville Airport, Knoxville Airport (USA) arriving at 12/16/2025 4:02:00 PM. 50 Economy ticket for $100 per person are available. Travel duration is 28h 5m
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Greyhound US5h 35m01:20 PMCincinnatiGreyhound Bus Station6:55 PMKnoxville, TNGreyhound Bus Station0EconomyA Bus from Greyhound US goes from Greyhound Bus Station, Cincinnati (USA) at 12/15/2025 1:20:00 PM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 12/15/2025 6:55:00 PM. 50 Economy ticket for $41 per person are available. Travel duration is 5h 35m
Fastest Flights Monday
Fastest Buses Monday
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Greyhound US5h 35m01:20 PMCincinnatiGreyhound Bus Station6:55 PMKnoxville, TNGreyhound Bus Station0EconomyA Bus from Greyhound US goes from Greyhound Bus Station, Cincinnati (USA) at 12/16/2025 1:20:00 PM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 12/16/2025 6:55:00 PM. 50 Economy ticket for $44 per person are available. Travel duration is 5h 35m
Fastest Buses Tuesday
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Skyscanner4h 28m010:20 AMCincinnati/Northern Kentucky AirportCincinnati/Northern Kentucky Airport2:48 PMKnoxville AirportKnoxville Airport0EconomyA Flight from Skyscanner goes from Cincinnati/Northern Kentucky Airport, Cincinnati/Northern Kentucky Airport (USA) at 12/18/2025 10:20:00 AM to Knoxville Airport, Knoxville Airport (USA) arriving at 12/18/2025 2:48:00 PM. 50 Economy ticket for $274 per person are available. Travel duration is 4h 28m
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Skyscanner4h 56m06:00 AMCincinnati/Northern Kentucky AirportCincinnati/Northern Kentucky Airport10:56 AMKnoxville AirportKnoxville Airport0EconomyA Flight from Skyscanner goes from Cincinnati/Northern Kentucky Airport, Cincinnati/Northern Kentucky Airport (USA) at 12/18/2025 6:00:00 AM to Knoxville Airport, Knoxville Airport (USA) arriving at 12/18/2025 10:56:00 AM. 50 Economy ticket for $274 per person are available. Travel duration is 4h 56m
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Frontier Airlines9h 57m011:57 AMCincinnati/Northern Kentucky AirportCincinnati/Northern Kentucky Airport9:54 PMKnoxville AirportKnoxville Airport0EconomyA Flight from Frontier Airlines goes from Cincinnati/Northern Kentucky Airport, Cincinnati/Northern Kentucky Airport (USA) at 12/18/2025 11:57:00 AM to Knoxville Airport, Knoxville Airport (USA) arriving at 12/18/2025 9:54:00 PM. 50 Economy ticket for $168 per person are available. Travel duration is 9h 57m
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Allegiant Air13h 13m09:19 PMCincinnati/Northern Kentucky AirportCincinnati/Northern Kentucky Airport10:32 AMKnoxville AirportKnoxville Airport0EconomyA Flight from Allegiant Air goes from Cincinnati/Northern Kentucky Airport, Cincinnati/Northern Kentucky Airport (USA) at 12/18/2025 9:19:00 PM to Knoxville Airport, Knoxville Airport (USA) arriving at 12/19/2025 10:32:00 AM. 50 Economy ticket for $194 per person are available. Travel duration is 13h 13m
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Allegiant Air15h 42m07:00 AMCincinnati/Northern Kentucky AirportCincinnati/Northern Kentucky Airport10:42 PMKnoxville AirportKnoxville Airport0EconomyA Flight from Allegiant Air goes from Cincinnati/Northern Kentucky Airport, Cincinnati/Northern Kentucky Airport (USA) at 12/18/2025 7:00:00 AM to Knoxville Airport, Knoxville Airport (USA) arriving at 12/18/2025 10:42:00 PM. 50 Economy ticket for $113 per person are available. Travel duration is 15h 42m
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Greyhound US5h 35m01:20 PMCincinnatiGreyhound Bus Station6:55 PMKnoxville, TNGreyhound Bus Station0EconomyA Bus from Greyhound US goes from Greyhound Bus Station, Cincinnati (USA) at 12/18/2025 1:20:00 PM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 12/18/2025 6:55:00 PM. 50 Economy ticket for $44 per person are available. Travel duration is 5h 35m
Fastest Flights Thursday
Fastest Buses Thursday
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Greyhound US5h 35m01:20 PMCincinnatiGreyhound Bus Station6:55 PMKnoxville, TNGreyhound Bus Station0EconomyA Bus from Greyhound US goes from Greyhound Bus Station, Cincinnati (USA) at 12/19/2025 1:20:00 PM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 12/19/2025 6:55:00 PM. 50 Economy ticket for $50 per person are available. Travel duration is 5h 35m
Fastest Buses Friday
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Skyscanner4h 54m05:45 PMCincinnati/Northern Kentucky AirportCincinnati/Northern Kentucky Airport10:39 PMKnoxville AirportKnoxville Airport0EconomyA Flight from Skyscanner goes from Cincinnati/Northern Kentucky Airport, Cincinnati/Northern Kentucky Airport (USA) at 12/20/2025 5:45:00 PM to Knoxville Airport, Knoxville Airport (USA) arriving at 12/20/2025 10:39:00 PM. 50 Economy ticket for $272 per person are available. Travel duration is 4h 54m
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Allegiant Air9h 13m012:21 PMCincinnati/Northern Kentucky AirportCincinnati/Northern Kentucky Airport9:34 PMKnoxville AirportKnoxville Airport0EconomyA Flight from Allegiant Air goes from Cincinnati/Northern Kentucky Airport, Cincinnati/Northern Kentucky Airport (USA) at 12/20/2025 12:21:00 PM to Knoxville Airport, Knoxville Airport (USA) arriving at 12/20/2025 9:34:00 PM. 50 Economy ticket for $165 per person are available. Travel duration is 9h 13m
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Frontier Airlines10h 33m06:00 AMCincinnati/Northern Kentucky AirportCincinnati/Northern Kentucky Airport4:33 PMKnoxville AirportKnoxville Airport0EconomyA Flight from Frontier Airlines goes from Cincinnati/Northern Kentucky Airport, Cincinnati/Northern Kentucky Airport (USA) at 12/20/2025 6:00:00 AM to Knoxville Airport, Knoxville Airport (USA) arriving at 12/20/2025 4:33:00 PM. 50 Economy ticket for $159 per person are available. Travel duration is 10h 33m
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Frontier Airlines15h 34m06:00 AMCincinnati/Northern Kentucky AirportCincinnati/Northern Kentucky Airport9:34 PMKnoxville AirportKnoxville Airport0EconomyA Flight from Frontier Airlines goes from Cincinnati/Northern Kentucky Airport, Cincinnati/Northern Kentucky Airport (USA) at 12/20/2025 6:00:00 AM to Knoxville Airport, Knoxville Airport (USA) arriving at 12/20/2025 9:34:00 PM. 50 Economy ticket for $140 per person are available. Travel duration is 15h 34m
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Allegiant Air26h 51m06:15 PMCincinnati/Northern Kentucky AirportCincinnati/Northern Kentucky Airport9:06 PMKnoxville AirportKnoxville Airport0EconomyA Flight from Allegiant Air goes from Cincinnati/Northern Kentucky Airport, Cincinnati/Northern Kentucky Airport (USA) at 12/20/2025 6:15:00 PM to Knoxville Airport, Knoxville Airport (USA) arriving at 12/21/2025 9:06:00 PM. 50 Economy ticket for $160 per person are available. Travel duration is 26h 51m
Fastest Flights Saturday
Here you will find all operators and timetables for a
Bus from Cincinnati to Knoxville, TN
What are the most popular stations in Cincinnati and Knoxville, TN?
In Cincinnati, you will usually depart from Downtown, Greyhound Bus Station or University of Cincinnati, while in Knoxville, TN you will be arriving at Knoxville Area Transit Bus Stop, Greyhound Bus Station or Transit Center, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Knoxville, TN from Cincinnati? With 4 connections between 1 Bus and Flight operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Cincinnati and Knoxville, TN, you can pay as low as $41 with a Bus from Greyhound US.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Skyscanner: you will get to Knoxville, TN in just 4h 17m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Cincinnati and Knoxville, TN are Frontier Airlines, Skyscanner and Allegiant Air, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Cincinnati and Knoxville, TN is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Covington, KY or to Wildwood, TN, and look at flights from Cincinnati/Northern Kentucky Airport, and landing at Knoxville Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Cincinnati to Knoxville, TN?
The most popular companies between Cincinnati and Knoxville, TN, are Frontier Airlines, Skyscanner and Allegiant Air. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: Greyhound US
Airlines: Frontier Airlines, Skyscanner, Allegiant Air and 1 more.
All you need to know when you travel from Cincinnati to Knoxville, TN
Check all information on comfort and services on all modes of transports from Cincinnati to Knoxville, TN. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Cincinnati to Knoxville, TN
How can I reach Knoxville, TN from Cincinnati?
Every day, there are on average 4 connections between Bus and Flight, with which you can get to Knoxville, TN from Cincinnati.
How far is Knoxville, TN from Cincinnati?
The distance between Cincinnati and Knoxville, TN is 219.4 miles.
What is the most ecofriendly mode of transport between Cincinnati and Knoxville, TN?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 10 kgs of CO2, a train 12 kgs, a car 60 kgs, and a flight 87 kgs.
What is the cheapest mode of transport from Cincinnati to Knoxville, TN?
You can get to Knoxville, TN with just $41 by taking a Bus from Greyhound US.
What is the fastest way to get from Cincinnati to Knoxville, TN?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Knoxville, TN in just 4h 17m with a Flight from Skyscanner.
More routes to Cincinnati and to Knoxville, TN
Looking for more options? Here you can see the most popular routes to Cincinnati and to Knoxville, TN. Simply click on a connection, and you’ll find all the details about the route!

