How to get from Philadelphia to Knoxville, TN

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What is the best way to travel from Philadelphia to Knoxville, TN?

Looking for a trip? Compare all the available Flights and Buses for the journey to Knoxville, TN from Philadelphia. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 2 available companies to find your perfect trip!
Bus is the cheapest, while Flight is the fastest way on this route
Transport type
Travel time
Cheapest price
Average price
Daily departures
Bus
16h 0m
$73
$80
12
Flight
4h 36m
$94
$222
57

What is the cheapest way to reach Knoxville, TN from Philadelphia?

You can get to Knoxville, TN with just $73 by taking a Bus from FlixBus, but you can find many more cheap offers: we have selected the best ones for next few days here for you.

Friday
from $82
Saturday
from $87
Sunday
from $81
Monday
from $73
Tuesday
from $76
Wednesday
from $82
Thursday
from $76

    Cheapest Buses Friday

  • FlixBus
    16h 10m
    0
    1:50 AM
    Philadelphia
    Spring Garden St Station
    6:00 PM
    Knoxville, TN
    Knoxville Area Transit Bus Stop
    0
    FlixBus
    Economy
    $82
  • Greyhound US
    16h 0m
    0
    2:00 AM
    Philadelphia
    Schuylkill Ave and Walnut Street
    6:00 PM
    Knoxville, TN
    Knoxville Area Transit Bus Stop
    0
    Greyhound US
    Economy
    $82
  • Greyhound US
    22h 0m
    0
    8:00 PM
    Philadelphia
    Schuylkill Ave and Walnut Street
    6:00 PM
    Knoxville, TN
    Knoxville Area Transit Bus Stop
    0
    Greyhound US
    Economy
    $82
  • Greyhound US
    21h 30m
    0
    8:30 PM
    Philadelphia
    Convention Center
    6:00 PM
    Knoxville, TN
    Knoxville Area Transit Bus Stop
    0
    Greyhound US
    Economy
    $82
  • FlixBus
    20h 0m
    0
    10:00 PM
    Philadelphia
    Spring Garden St Station
    6:00 PM
    Knoxville, TN
    Knoxville Area Transit Bus Stop
    0
    FlixBus
    Economy
    $84
  • Cheapest Flights Friday

  • Allegiant Air
    17h 54m
    0
    6:12 PM
    Philadelphia Airport
    Philadelphia Airport
    12:06 PM
    Knoxville Airport
    Knoxville Airport
    0
    Allegiant Air
    Economy
    from $126
  • Spirit Airlines
    17h 54m
    0
    6:12 PM
    Philadelphia Airport
    Philadelphia Airport
    12:06 PM
    Knoxville Airport
    Knoxville Airport
    0
    Spirit Airlines
    Economy
    from $163
  • Frontier Airlines
    18h 34m
    0
    5:32 PM
    Philadelphia Airport
    Philadelphia Airport
    12:06 PM
    Knoxville Airport
    Knoxville Airport
    0
    Frontier Airlines
    Economy
    from $181
  • United Airlines
    24h 54m
    0
    12:55 PM
    Philadelphia Airport
    Philadelphia Airport
    1:49 PM
    Knoxville Airport
    Knoxville Airport
    0
    United Airlines
    Economy
    from $359
  • Skyscanner
    4h 36m
    0
    10:33 AM
    Philadelphia Airport
    Philadelphia Airport
    3:09 PM
    Knoxville Airport
    Knoxville Airport
    0
    Skyscanner
    Economy
    from $479

    Cheapest Buses Saturday

  • FlixBus
    16h 10m
    0
    1:50 AM
    Philadelphia
    Spring Garden St Station
    6:00 PM
    Knoxville, TN
    Knoxville Area Transit Bus Stop
    0
    FlixBus
    Economy
    $87
  • Greyhound US
    16h 0m
    0
    2:00 AM
    Philadelphia
    Schuylkill Ave and Walnut Street
    6:00 PM
    Knoxville, TN
    Knoxville Area Transit Bus Stop
    0
    Greyhound US
    Economy
    $87
  • Greyhound US
    22h 0m
    0
    8:00 PM
    Philadelphia
    Schuylkill Ave and Walnut Street
    6:00 PM
    Knoxville, TN
    Knoxville Area Transit Bus Stop
    0
    Greyhound US
    Economy
    $87
  • Greyhound US
    21h 30m
    0
    8:30 PM
    Philadelphia
    Convention Center
    6:00 PM
    Knoxville, TN
    Knoxville Area Transit Bus Stop
    0
    Greyhound US
    Economy
    $87
  • FlixBus
    20h 0m
    0
    10:00 PM
    Philadelphia
    Spring Garden St Station
    6:00 PM
    Knoxville, TN
    Knoxville Area Transit Bus Stop
    0
    FlixBus
    Economy
    $88
  • Cheapest Flights Saturday

  • Frontier Airlines
    18h 52m
    0
    8:41 PM
    Philadelphia Airport
    Philadelphia Airport
    3:33 PM
    Knoxville Airport
    Knoxville Airport
    0
    Frontier Airlines
    Economy
    from $97
  • Frontier Airlines
    27h 37m
    0
    6:56 PM
    Philadelphia Airport
    Philadelphia Airport
    10:33 PM
    Knoxville Airport
    Knoxville Airport
    0
    Frontier Airlines
    Economy
    from $150
  • Spirit Airlines
    26h 30m
    0
    6:12 PM
    Philadelphia Airport
    Philadelphia Airport
    8:42 PM
    Knoxville Airport
    Knoxville Airport
    0
    Spirit Airlines
    Economy
    from $176
  • Spirit Airlines
    20h 33m
    0
    6:12 PM
    Philadelphia Airport
    Philadelphia Airport
    2:45 PM
    Knoxville Airport
    Knoxville Airport
    0
    Spirit Airlines
    Economy
    from $189
  • Skyscanner
    26h 50m
    0
    5:50 PM
    Greater Wilmington Airport
    Greater Wilmington Airport
    8:40 PM
    Knoxville Airport
    Knoxville Airport
    0
    Skyscanner
    Economy
    from $205

    Cheapest Buses Sunday

  • FlixBus
    20h 0m
    0
    10:00 PM
    Philadelphia
    Spring Garden St Station
    6:00 PM
    Knoxville, TN
    Knoxville Area Transit Bus Stop
    0
    FlixBus
    Economy
    $81
  • FlixBus
    16h 10m
    0
    1:50 AM
    Philadelphia
    Spring Garden St Station
    6:00 PM
    Knoxville, TN
    Knoxville Area Transit Bus Stop
    0
    FlixBus
    Economy
    $82
  • Greyhound US
    16h 0m
    0
    2:00 AM
    Philadelphia
    Schuylkill Ave and Walnut Street
    6:00 PM
    Knoxville, TN
    Knoxville Area Transit Bus Stop
    0
    Greyhound US
    Economy
    $82
  • Greyhound US
    22h 0m
    0
    8:00 PM
    Philadelphia
    Schuylkill Ave and Walnut Street
    6:00 PM
    Knoxville, TN
    Knoxville Area Transit Bus Stop
    0
    Greyhound US
    Economy
    $82
  • Greyhound US
    21h 30m
    0
    8:30 PM
    Philadelphia
    Convention Center
    6:00 PM
    Knoxville, TN
    Knoxville Area Transit Bus Stop
    0
    Greyhound US
    Economy
    $82
  • Cheapest Flights Sunday

  • Frontier Airlines
    23h 46m
    0
    10:38 PM
    Philadelphia Airport
    Philadelphia Airport
    10:24 PM
    Knoxville Airport
    Knoxville Airport
    0
    Frontier Airlines
    Economy
    from $107
  • Allegiant Air
    17h 10m
    0
    7:15 PM
    Trenton–Mercer Airport
    Trenton–Mercer Airport
    12:25 PM
    Knoxville Airport
    Knoxville Airport
    0
    Allegiant Air
    Economy
    from $156
  • Spirit Airlines
    14h 57m
    0
    5:45 AM
    Philadelphia Airport
    Philadelphia Airport
    8:42 PM
    Knoxville Airport
    Knoxville Airport
    0
    Spirit Airlines
    Economy
    from $182
  • Skyscanner
    12h 12m
    0
    8:30 AM
    Greater Wilmington Airport
    Greater Wilmington Airport
    8:42 PM
    Knoxville Airport
    Knoxville Airport
    0
    Skyscanner
    Economy
    from $187
  • United Airlines
    28h 4m
    0
    6:04 AM
    Philadelphia Airport
    Philadelphia Airport
    10:08 AM
    Knoxville Airport
    Knoxville Airport
    0
    United Airlines
    Economy
    from $369

    Cheapest Buses Monday

  • FlixBus
    16h 10m
    0
    1:50 AM
    Philadelphia
    Spring Garden St Station
    6:00 PM
    Knoxville, TN
    Knoxville Area Transit Bus Stop
    0
    FlixBus
    Economy
    $73
  • FlixBus
    20h 0m
    0
    10:00 PM
    Philadelphia
    Spring Garden St Station
    6:00 PM
    Knoxville, TN
    Knoxville Area Transit Bus Stop
    0
    FlixBus
    Economy
    $73
  • Greyhound US
    16h 0m
    0
    2:00 AM
    Philadelphia
    Schuylkill Ave and Walnut Street
    6:00 PM
    Knoxville, TN
    Knoxville Area Transit Bus Stop
    0
    Greyhound US
    Economy
    $73
  • Greyhound US
    21h 30m
    0
    8:30 PM
    Philadelphia
    Convention Center
    6:00 PM
    Knoxville, TN
    Knoxville Area Transit Bus Stop
    0
    Greyhound US
    Economy
    $73
  • Greyhound US
    22h 0m
    0
    8:00 PM
    Philadelphia
    Schuylkill Ave and Walnut Street
    6:00 PM
    Knoxville, TN
    Knoxville Area Transit Bus Stop
    0
    Greyhound US
    Economy
    $75
  • Cheapest Flights Monday

  • Allegiant Air
    26h 14m
    0
    12:44 PM
    Trenton–Mercer Airport
    Trenton–Mercer Airport
    2:58 PM
    Knoxville Airport
    Knoxville Airport
    0
    Allegiant Air
    Economy
    from $111
  • Frontier Airlines
    14h 54m
    0
    7:30 AM
    Philadelphia Airport
    Philadelphia Airport
    10:24 PM
    Knoxville Airport
    Knoxville Airport
    0
    Frontier Airlines
    Economy
    from $114
  • Spirit Airlines
    26h 10m
    0
    7:30 AM
    Philadelphia Airport
    Philadelphia Airport
    9:40 AM
    Knoxville Airport
    Knoxville Airport
    0
    Spirit Airlines
    Economy
    from $114
  • United Airlines
    5h 34m
    0
    5:00 PM
    Philadelphia Airport
    Philadelphia Airport
    10:34 PM
    Knoxville Airport
    Knoxville Airport
    0
    United Airlines
    Economy
    from $320
  • Skyscanner
    4h 36m
    0
    10:33 AM
    Philadelphia Airport
    Philadelphia Airport
    3:09 PM
    Knoxville Airport
    Knoxville Airport
    0
    Skyscanner
    Economy
    from $480

    Cheapest Buses Tuesday

  • FlixBus
    20h 0m
    0
    10:00 PM
    Philadelphia
    Spring Garden St Station
    6:00 PM
    Knoxville, TN
    Knoxville Area Transit Bus Stop
    0
    FlixBus
    Economy
    $76
  • Greyhound US
    22h 0m
    0
    8:00 PM
    Philadelphia
    Schuylkill Ave and Walnut Street
    6:00 PM
    Knoxville, TN
    Knoxville Area Transit Bus Stop
    0
    Greyhound US
    Economy
    $76
  • FlixBus
    16h 10m
    0
    1:50 AM
    Philadelphia
    Spring Garden St Station
    6:00 PM
    Knoxville, TN
    Knoxville Area Transit Bus Stop
    0
    FlixBus
    Economy
    $77
  • Greyhound US
    16h 0m
    0
    2:00 AM
    Philadelphia
    Schuylkill Ave and Walnut Street
    6:00 PM
    Knoxville, TN
    Knoxville Area Transit Bus Stop
    0
    Greyhound US
    Economy
    $77
  • Greyhound US
    21h 30m
    0
    8:30 PM
    Philadelphia
    Convention Center
    6:00 PM
    Knoxville, TN
    Knoxville Area Transit Bus Stop
    0
    Greyhound US
    Economy
    $77
  • Cheapest Flights Tuesday

  • Frontier Airlines
    21h 6m
    0
    1:30 PM
    Philadelphia Airport
    Philadelphia Airport
    10:36 AM
    Knoxville Airport
    Knoxville Airport
    0
    Frontier Airlines
    Economy
    from $99
  • Spirit Airlines
    28h 51m
    0
    5:45 AM
    Philadelphia Airport
    Philadelphia Airport
    10:36 AM
    Knoxville Airport
    Knoxville Airport
    0
    Spirit Airlines
    Economy
    from $110
  • Spirit Airlines
    16h 24m
    0
    6:12 PM
    Philadelphia Airport
    Philadelphia Airport
    10:36 AM
    Knoxville Airport
    Knoxville Airport
    0
    Spirit Airlines
    Economy
    from $110
  • United Airlines
    12h 34m
    0
    10:00 AM
    Philadelphia Airport
    Philadelphia Airport
    10:34 PM
    Knoxville Airport
    Knoxville Airport
    0
    United Airlines
    Economy
    from $369

    Cheapest Buses Wednesday

  • FlixBus
    24h 15m
    0
    5:45 PM
    Philadelphia
    Spring Garden St Station
    6:00 PM
    Knoxville, TN
    Knoxville Area Transit Bus Stop
    0
    FlixBus
    Economy
    $82
  • FlixBus
    27h 20m
    0
    6:30 PM
    Philadelphia
    Spring Garden St Station
    9:50 PM
    Knoxville, TN
    Knoxville Area Transit Bus Stop
    0
    FlixBus
    Economy
    $82
  • Greyhound US
    16h 0m
    0
    2:00 AM
    Philadelphia
    Schuylkill Ave and Walnut Street
    6:00 PM
    Knoxville, TN
    Knoxville Area Transit Bus Stop
    0
    Greyhound US
    Economy
    $82
  • FlixBus
    16h 10m
    0
    1:50 AM
    Philadelphia
    Spring Garden St Station
    6:00 PM
    Knoxville, TN
    Knoxville Area Transit Bus Stop
    0
    FlixBus
    Economy
    $83
  • Greyhound US
    22h 0m
    0
    8:00 PM
    Philadelphia
    Schuylkill Ave and Walnut Street
    6:00 PM
    Knoxville, TN
    Knoxville Area Transit Bus Stop
    0
    Greyhound US
    Economy
    $83
  • Cheapest Flights Wednesday

  • Allegiant Air
    26h 30m
    0
    6:12 PM
    Philadelphia Airport
    Philadelphia Airport
    8:42 PM
    Knoxville Airport
    Knoxville Airport
    0
    Allegiant Air
    Economy
    from $94
  • Spirit Airlines
    26h 30m
    0
    6:12 PM
    Philadelphia Airport
    Philadelphia Airport
    8:42 PM
    Knoxville Airport
    Knoxville Airport
    0
    Spirit Airlines
    Economy
    from $99
  • Frontier Airlines
    25h 15m
    0
    1:30 PM
    Philadelphia Airport
    Philadelphia Airport
    2:45 PM
    Knoxville Airport
    Knoxville Airport
    0
    Frontier Airlines
    Economy
    from $133
  • United Airlines
    13h 8m
    0
    10:00 AM
    Philadelphia Airport
    Philadelphia Airport
    11:08 PM
    Knoxville Airport
    Knoxville Airport
    0
    United Airlines
    Economy
    from $369
  • Skyscanner
    4h 36m
    0
    10:33 AM
    Philadelphia Airport
    Philadelphia Airport
    3:09 PM
    Knoxville Airport
    Knoxville Airport
    0
    Skyscanner
    Economy
    from $469

    Cheapest Buses Thursday

  • FlixBus
    27h 20m
    0
    6:30 PM
    Philadelphia
    Spring Garden St Station
    9:50 PM
    Knoxville, TN
    Knoxville Area Transit Bus Stop
    0
    FlixBus
    Economy
    $76
  • FlixBus
    16h 10m
    0
    1:50 AM
    Philadelphia
    Spring Garden St Station
    6:00 PM
    Knoxville, TN
    Knoxville Area Transit Bus Stop
    0
    FlixBus
    Economy
    $77
  • FlixBus
    24h 15m
    0
    5:45 PM
    Philadelphia
    Spring Garden St Station
    6:00 PM
    Knoxville, TN
    Knoxville Area Transit Bus Stop
    0
    FlixBus
    Economy
    $77
  • Greyhound US
    16h 0m
    0
    2:00 AM
    Philadelphia
    Schuylkill Ave and Walnut Street
    6:00 PM
    Knoxville, TN
    Knoxville Area Transit Bus Stop
    0
    Greyhound US
    Economy
    $77
  • Greyhound US
    21h 30m
    0
    8:30 PM
    Philadelphia
    Convention Center
    6:00 PM
    Knoxville, TN
    Knoxville Area Transit Bus Stop
    0
    Greyhound US
    Economy
    $77
  • Cheapest Flights Thursday

  • Allegiant Air
    14h 57m
    0
    5:45 AM
    Philadelphia Airport
    Philadelphia Airport
    8:42 PM
    Knoxville Airport
    Knoxville Airport
    0
    Allegiant Air
    Economy
    from $98
  • Spirit Airlines
    14h 57m
    0
    5:45 AM
    Philadelphia Airport
    Philadelphia Airport
    8:42 PM
    Knoxville Airport
    Knoxville Airport
    0
    Spirit Airlines
    Economy
    from $116
  • Frontier Airlines
    15h 42m
    0
    6:15 AM
    Philadelphia Airport
    Philadelphia Airport
    9:57 PM
    Knoxville Airport
    Knoxville Airport
    0
    Frontier Airlines
    Economy
    from $163
  • United Airlines
    12h 34m
    0
    10:00 AM
    Philadelphia Airport
    Philadelphia Airport
    10:34 PM
    Knoxville Airport
    Knoxville Airport
    0
    United Airlines
    Economy
    from $435
  • Skyscanner
    4h 36m
    0
    10:33 AM
    Philadelphia Airport
    Philadelphia Airport
    3:09 PM
    Knoxville Airport
    Knoxville Airport
    0
    Skyscanner
    Economy
    from $605

What are the fastest trips from Philadelphia to Knoxville, TN?

You can get to Knoxville, TN from Philadelphia in just 4h 36m with a Flight from Skyscanner. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.

Friday
from 4h 36m
Saturday
from 16h 0m
Sunday
from 12h 12m
Monday
from 4h 36m
Tuesday
from 12h 34m
Wednesday
from 4h 36m
Thursday
from 4h 36m

    Fastest Flights Friday

  • Skyscanner
    4h 36m
    0
    10:33 AM
    Philadelphia Airport
    Philadelphia Airport
    3:09 PM
    Knoxville Airport
    Knoxville Airport
    0
    Skyscanner
    Economy
    from $479
  • Allegiant Air
    17h 54m
    0
    6:12 PM
    Philadelphia Airport
    Philadelphia Airport
    12:06 PM
    Knoxville Airport
    Knoxville Airport
    0
    Allegiant Air
    Economy
    from $126
  • Spirit Airlines
    17h 54m
    0
    6:12 PM
    Philadelphia Airport
    Philadelphia Airport
    12:06 PM
    Knoxville Airport
    Knoxville Airport
    0
    Spirit Airlines
    Economy
    from $163
  • Frontier Airlines
    18h 34m
    0
    5:32 PM
    Philadelphia Airport
    Philadelphia Airport
    12:06 PM
    Knoxville Airport
    Knoxville Airport
    0
    Frontier Airlines
    Economy
    from $181
  • United Airlines
    24h 54m
    0
    12:55 PM
    Philadelphia Airport
    Philadelphia Airport
    1:49 PM
    Knoxville Airport
    Knoxville Airport
    0
    United Airlines
    Economy
    from $359
  • Fastest Buses Friday

  • Greyhound US
    16h 0m
    0
    2:00 AM
    Philadelphia
    Schuylkill Ave and Walnut Street
    6:00 PM
    Knoxville, TN
    Knoxville Area Transit Bus Stop
    0
    Greyhound US
    Economy
    $82
  • FlixBus
    16h 10m
    0
    1:50 AM
    Philadelphia
    Spring Garden St Station
    6:00 PM
    Knoxville, TN
    Knoxville Area Transit Bus Stop
    0
    FlixBus
    Economy
    $82
  • FlixBus
    20h 0m
    0
    10:00 PM
    Philadelphia
    Spring Garden St Station
    6:00 PM
    Knoxville, TN
    Knoxville Area Transit Bus Stop
    0
    FlixBus
    Economy
    $84
  • Greyhound US
    21h 30m
    0
    8:30 PM
    Philadelphia
    Convention Center
    6:00 PM
    Knoxville, TN
    Knoxville Area Transit Bus Stop
    0
    Greyhound US
    Economy
    $82
  • Greyhound US
    22h 0m
    0
    8:00 PM
    Philadelphia
    Schuylkill Ave and Walnut Street
    6:00 PM
    Knoxville, TN
    Knoxville Area Transit Bus Stop
    0
    Greyhound US
    Economy
    $82

    Fastest Buses Saturday

  • Greyhound US
    16h 0m
    0
    2:00 AM
    Philadelphia
    Schuylkill Ave and Walnut Street
    6:00 PM
    Knoxville, TN
    Knoxville Area Transit Bus Stop
    0
    Greyhound US
    Economy
    $87
  • FlixBus
    16h 10m
    0
    1:50 AM
    Philadelphia
    Spring Garden St Station
    6:00 PM
    Knoxville, TN
    Knoxville Area Transit Bus Stop
    0
    FlixBus
    Economy
    $87
  • FlixBus
    20h 0m
    0
    10:00 PM
    Philadelphia
    Spring Garden St Station
    6:00 PM
    Knoxville, TN
    Knoxville Area Transit Bus Stop
    0
    FlixBus
    Economy
    $88
  • Greyhound US
    21h 30m
    0
    8:30 PM
    Philadelphia
    Convention Center
    6:00 PM
    Knoxville, TN
    Knoxville Area Transit Bus Stop
    0
    Greyhound US
    Economy
    $87
  • Greyhound US
    22h 0m
    0
    8:00 PM
    Philadelphia
    Schuylkill Ave and Walnut Street
    6:00 PM
    Knoxville, TN
    Knoxville Area Transit Bus Stop
    0
    Greyhound US
    Economy
    $87
  • Fastest Flights Saturday

  • Frontier Airlines
    18h 52m
    0
    8:41 PM
    Philadelphia Airport
    Philadelphia Airport
    3:33 PM
    Knoxville Airport
    Knoxville Airport
    0
    Frontier Airlines
    Economy
    from $97
  • Spirit Airlines
    20h 33m
    0
    6:12 PM
    Philadelphia Airport
    Philadelphia Airport
    2:45 PM
    Knoxville Airport
    Knoxville Airport
    0
    Spirit Airlines
    Economy
    from $189
  • Spirit Airlines
    26h 30m
    0
    6:12 PM
    Philadelphia Airport
    Philadelphia Airport
    8:42 PM
    Knoxville Airport
    Knoxville Airport
    0
    Spirit Airlines
    Economy
    from $176
  • Skyscanner
    26h 50m
    0
    5:50 PM
    Greater Wilmington Airport
    Greater Wilmington Airport
    8:40 PM
    Knoxville Airport
    Knoxville Airport
    0
    Skyscanner
    Economy
    from $205
  • Frontier Airlines
    27h 37m
    0
    6:56 PM
    Philadelphia Airport
    Philadelphia Airport
    10:33 PM
    Knoxville Airport
    Knoxville Airport
    0
    Frontier Airlines
    Economy
    from $150

    Fastest Flights Sunday

  • Skyscanner
    12h 12m
    0
    8:30 AM
    Greater Wilmington Airport
    Greater Wilmington Airport
    8:42 PM
    Knoxville Airport
    Knoxville Airport
    0
    Skyscanner
    Economy
    from $187
  • Spirit Airlines
    14h 57m
    0
    5:45 AM
    Philadelphia Airport
    Philadelphia Airport
    8:42 PM
    Knoxville Airport
    Knoxville Airport
    0
    Spirit Airlines
    Economy
    from $182
  • Allegiant Air
    17h 10m
    0
    7:15 PM
    Trenton–Mercer Airport
    Trenton–Mercer Airport
    12:25 PM
    Knoxville Airport
    Knoxville Airport
    0
    Allegiant Air
    Economy
    from $156
  • Frontier Airlines
    23h 46m
    0
    10:38 PM
    Philadelphia Airport
    Philadelphia Airport
    10:24 PM
    Knoxville Airport
    Knoxville Airport
    0
    Frontier Airlines
    Economy
    from $107
  • United Airlines
    28h 4m
    0
    6:04 AM
    Philadelphia Airport
    Philadelphia Airport
    10:08 AM
    Knoxville Airport
    Knoxville Airport
    0
    United Airlines
    Economy
    from $369
  • Fastest Buses Sunday

  • Greyhound US
    16h 0m
    0
    2:00 AM
    Philadelphia
    Schuylkill Ave and Walnut Street
    6:00 PM
    Knoxville, TN
    Knoxville Area Transit Bus Stop
    0
    Greyhound US
    Economy
    $82
  • FlixBus
    16h 10m
    0
    1:50 AM
    Philadelphia
    Spring Garden St Station
    6:00 PM
    Knoxville, TN
    Knoxville Area Transit Bus Stop
    0
    FlixBus
    Economy
    $82
  • FlixBus
    20h 0m
    0
    10:00 PM
    Philadelphia
    Spring Garden St Station
    6:00 PM
    Knoxville, TN
    Knoxville Area Transit Bus Stop
    0
    FlixBus
    Economy
    $81
  • Greyhound US
    21h 30m
    0
    8:30 PM
    Philadelphia
    Convention Center
    6:00 PM
    Knoxville, TN
    Knoxville Area Transit Bus Stop
    0
    Greyhound US
    Economy
    $82
  • Greyhound US
    22h 0m
    0
    8:00 PM
    Philadelphia
    Schuylkill Ave and Walnut Street
    6:00 PM
    Knoxville, TN
    Knoxville Area Transit Bus Stop
    0
    Greyhound US
    Economy
    $82

    Fastest Flights Monday

  • Skyscanner
    4h 36m
    0
    10:33 AM
    Philadelphia Airport
    Philadelphia Airport
    3:09 PM
    Knoxville Airport
    Knoxville Airport
    0
    Skyscanner
    Economy
    from $480
  • United Airlines
    5h 34m
    0
    5:00 PM
    Philadelphia Airport
    Philadelphia Airport
    10:34 PM
    Knoxville Airport
    Knoxville Airport
    0
    United Airlines
    Economy
    from $320
  • Frontier Airlines
    14h 54m
    0
    7:30 AM
    Philadelphia Airport
    Philadelphia Airport
    10:24 PM
    Knoxville Airport
    Knoxville Airport
    0
    Frontier Airlines
    Economy
    from $114
  • Spirit Airlines
    26h 10m
    0
    7:30 AM
    Philadelphia Airport
    Philadelphia Airport
    9:40 AM
    Knoxville Airport
    Knoxville Airport
    0
    Spirit Airlines
    Economy
    from $114
  • Allegiant Air
    26h 14m
    0
    12:44 PM
    Trenton–Mercer Airport
    Trenton–Mercer Airport
    2:58 PM
    Knoxville Airport
    Knoxville Airport
    0
    Allegiant Air
    Economy
    from $111
  • Fastest Buses Monday

  • Greyhound US
    16h 0m
    0
    2:00 AM
    Philadelphia
    Schuylkill Ave and Walnut Street
    6:00 PM
    Knoxville, TN
    Knoxville Area Transit Bus Stop
    0
    Greyhound US
    Economy
    $73
  • FlixBus
    16h 10m
    0
    1:50 AM
    Philadelphia
    Spring Garden St Station
    6:00 PM
    Knoxville, TN
    Knoxville Area Transit Bus Stop
    0
    FlixBus
    Economy
    $73
  • FlixBus
    20h 0m
    0
    10:00 PM
    Philadelphia
    Spring Garden St Station
    6:00 PM
    Knoxville, TN
    Knoxville Area Transit Bus Stop
    0
    FlixBus
    Economy
    $73
  • Greyhound US
    21h 30m
    0
    8:30 PM
    Philadelphia
    Convention Center
    6:00 PM
    Knoxville, TN
    Knoxville Area Transit Bus Stop
    0
    Greyhound US
    Economy
    $73
  • Greyhound US
    22h 0m
    0
    8:00 PM
    Philadelphia
    Schuylkill Ave and Walnut Street
    6:00 PM
    Knoxville, TN
    Knoxville Area Transit Bus Stop
    0
    Greyhound US
    Economy
    $75

    Fastest Flights Tuesday

  • United Airlines
    12h 34m
    0
    10:00 AM
    Philadelphia Airport
    Philadelphia Airport
    10:34 PM
    Knoxville Airport
    Knoxville Airport
    0
    United Airlines
    Economy
    from $369
  • Spirit Airlines
    16h 24m
    0
    6:12 PM
    Philadelphia Airport
    Philadelphia Airport
    10:36 AM
    Knoxville Airport
    Knoxville Airport
    0
    Spirit Airlines
    Economy
    from $110
  • Frontier Airlines
    21h 6m
    0
    1:30 PM
    Philadelphia Airport
    Philadelphia Airport
    10:36 AM
    Knoxville Airport
    Knoxville Airport
    0
    Frontier Airlines
    Economy
    from $99
  • Spirit Airlines
    28h 51m
    0
    5:45 AM
    Philadelphia Airport
    Philadelphia Airport
    10:36 AM
    Knoxville Airport
    Knoxville Airport
    0
    Spirit Airlines
    Economy
    from $110
  • Fastest Buses Tuesday

  • Greyhound US
    16h 0m
    0
    2:00 AM
    Philadelphia
    Schuylkill Ave and Walnut Street
    6:00 PM
    Knoxville, TN
    Knoxville Area Transit Bus Stop
    0
    Greyhound US
    Economy
    $77
  • FlixBus
    16h 10m
    0
    1:50 AM
    Philadelphia
    Spring Garden St Station
    6:00 PM
    Knoxville, TN
    Knoxville Area Transit Bus Stop
    0
    FlixBus
    Economy
    $77
  • FlixBus
    20h 0m
    0
    10:00 PM
    Philadelphia
    Spring Garden St Station
    6:00 PM
    Knoxville, TN
    Knoxville Area Transit Bus Stop
    0
    FlixBus
    Economy
    $76
  • Greyhound US
    21h 30m
    0
    8:30 PM
    Philadelphia
    Convention Center
    6:00 PM
    Knoxville, TN
    Knoxville Area Transit Bus Stop
    0
    Greyhound US
    Economy
    $77
  • Greyhound US
    22h 0m
    0
    8:00 PM
    Philadelphia
    Schuylkill Ave and Walnut Street
    6:00 PM
    Knoxville, TN
    Knoxville Area Transit Bus Stop
    0
    Greyhound US
    Economy
    $76

    Fastest Flights Wednesday

  • Skyscanner
    4h 36m
    0
    10:33 AM
    Philadelphia Airport
    Philadelphia Airport
    3:09 PM
    Knoxville Airport
    Knoxville Airport
    0
    Skyscanner
    Economy
    from $469
  • United Airlines
    13h 8m
    0
    10:00 AM
    Philadelphia Airport
    Philadelphia Airport
    11:08 PM
    Knoxville Airport
    Knoxville Airport
    0
    United Airlines
    Economy
    from $369
  • Frontier Airlines
    25h 15m
    0
    1:30 PM
    Philadelphia Airport
    Philadelphia Airport
    2:45 PM
    Knoxville Airport
    Knoxville Airport
    0
    Frontier Airlines
    Economy
    from $133
  • Allegiant Air
    26h 30m
    0
    6:12 PM
    Philadelphia Airport
    Philadelphia Airport
    8:42 PM
    Knoxville Airport
    Knoxville Airport
    0
    Allegiant Air
    Economy
    from $94
  • Spirit Airlines
    26h 30m
    0
    6:12 PM
    Philadelphia Airport
    Philadelphia Airport
    8:42 PM
    Knoxville Airport
    Knoxville Airport
    0
    Spirit Airlines
    Economy
    from $99
  • Fastest Buses Wednesday

  • Greyhound US
    16h 0m
    0
    2:00 AM
    Philadelphia
    Schuylkill Ave and Walnut Street
    6:00 PM
    Knoxville, TN
    Knoxville Area Transit Bus Stop
    0
    Greyhound US
    Economy
    $82
  • FlixBus
    16h 10m
    0
    1:50 AM
    Philadelphia
    Spring Garden St Station
    6:00 PM
    Knoxville, TN
    Knoxville Area Transit Bus Stop
    0
    FlixBus
    Economy
    $83
  • Greyhound US
    22h 0m
    0
    8:00 PM
    Philadelphia
    Schuylkill Ave and Walnut Street
    6:00 PM
    Knoxville, TN
    Knoxville Area Transit Bus Stop
    0
    Greyhound US
    Economy
    $83
  • FlixBus
    24h 15m
    0
    5:45 PM
    Philadelphia
    Spring Garden St Station
    6:00 PM
    Knoxville, TN
    Knoxville Area Transit Bus Stop
    0
    FlixBus
    Economy
    $82
  • FlixBus
    27h 20m
    0
    6:30 PM
    Philadelphia
    Spring Garden St Station
    9:50 PM
    Knoxville, TN
    Knoxville Area Transit Bus Stop
    0
    FlixBus
    Economy
    $82

    Fastest Flights Thursday

  • Skyscanner
    4h 36m
    0
    10:33 AM
    Philadelphia Airport
    Philadelphia Airport
    3:09 PM
    Knoxville Airport
    Knoxville Airport
    0
    Skyscanner
    Economy
    from $605
  • United Airlines
    12h 34m
    0
    10:00 AM
    Philadelphia Airport
    Philadelphia Airport
    10:34 PM
    Knoxville Airport
    Knoxville Airport
    0
    United Airlines
    Economy
    from $435
  • Allegiant Air
    14h 57m
    0
    5:45 AM
    Philadelphia Airport
    Philadelphia Airport
    8:42 PM
    Knoxville Airport
    Knoxville Airport
    0
    Allegiant Air
    Economy
    from $98
  • Spirit Airlines
    14h 57m
    0
    5:45 AM
    Philadelphia Airport
    Philadelphia Airport
    8:42 PM
    Knoxville Airport
    Knoxville Airport
    0
    Spirit Airlines
    Economy
    from $116
  • Frontier Airlines
    15h 42m
    0
    6:15 AM
    Philadelphia Airport
    Philadelphia Airport
    9:57 PM
    Knoxville Airport
    Knoxville Airport
    0
    Frontier Airlines
    Economy
    from $163
  • Fastest Buses Thursday

  • Greyhound US
    16h 0m
    0
    2:00 AM
    Philadelphia
    Schuylkill Ave and Walnut Street
    6:00 PM
    Knoxville, TN
    Knoxville Area Transit Bus Stop
    0
    Greyhound US
    Economy
    $77
  • FlixBus
    16h 10m
    0
    1:50 AM
    Philadelphia
    Spring Garden St Station
    6:00 PM
    Knoxville, TN
    Knoxville Area Transit Bus Stop
    0
    FlixBus
    Economy
    $77
  • Greyhound US
    21h 30m
    0
    8:30 PM
    Philadelphia
    Convention Center
    6:00 PM
    Knoxville, TN
    Knoxville Area Transit Bus Stop
    0
    Greyhound US
    Economy
    $77
  • FlixBus
    24h 15m
    0
    5:45 PM
    Philadelphia
    Spring Garden St Station
    6:00 PM
    Knoxville, TN
    Knoxville Area Transit Bus Stop
    0
    FlixBus
    Economy
    $77
  • FlixBus
    27h 20m
    0
    6:30 PM
    Philadelphia
    Spring Garden St Station
    9:50 PM
    Knoxville, TN
    Knoxville Area Transit Bus Stop
    0
    FlixBus
    Economy
    $76
Here you will find all operators and timetables for a Bus from Philadelphia to Knoxville, TN

What are the most popular stations in Philadelphia and Knoxville, TN?

In Philadelphia, you will usually depart from Spring Garden St Station, 30th Street Station or The Gallery, while in Knoxville, TN you will be arriving at Knoxville Area Transit Bus Stop, Greyhound Bus Station or Transit Center, but there are many more stops to explore in both locations.

How do I decide? Some tips and tricks from our experience

Are you having trouble deciding on how to get to Knoxville, TN from Philadelphia? With 10 connections between 2 Flight and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.

Look for the lowest price

Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Philadelphia and Knoxville, TN, you can pay as low as $73 with a Bus from FlixBus.

Travel duration

Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Skyscanner: you will get to Knoxville, TN in just 4h 36m.

Comfort makes all the difference

You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Philadelphia and Knoxville, TN are Greyhound US, FlixBus and Frontier Airlines, but be sure to check what they have to offer!

Save money with deals, and always compare

One last tip? Even if you live in Philadelphia and Knoxville, TN is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Millbourne, PA or to Wildwood, TN, and look at flights from Greater Wilmington Airport, and landing at Knoxville Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!

Which companies offer a trip from Philadelphia to Knoxville, TN?

The most popular companies between Philadelphia and Knoxville, TN, are Greyhound US, FlixBus and Frontier Airlines. Be sure to check their seat class offers and the amenities that they provide.

Bus companies: Greyhound US and FlixBus

Airlines: Frontier Airlines, Spirit Airlines, Skyscanner and 2 more.

All you need to know when you travel from Philadelphia to Knoxville, TN

Check all information on comfort and services on all modes of transports from Philadelphia to Knoxville, TN. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.

FAQs about the trip from Philadelphia to Knoxville, TN

How can I reach Knoxville, TN from Philadelphia?

Every day, there are on average 10 connections between Flight and Bus, with which you can get to Knoxville, TN from Philadelphia.

How far is Knoxville, TN from Philadelphia?

The distance between Philadelphia and Knoxville, TN is 549.6 miles.

What is the most ecofriendly mode of transport between Philadelphia and Knoxville, TN?

Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance. On this particular route, a bus will emit, per person, a total of 24 kgs of CO2, a train 31 kgs, a car 150 kgs, and a flight 218 kgs.

What is the cheapest mode of transport from Philadelphia to Knoxville, TN?

You can get to Knoxville, TN with just $73 by taking a Bus from FlixBus.

What is the fastest way to get from Philadelphia to Knoxville, TN?

While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Knoxville, TN in just 4h 36m with a Flight from Skyscanner.

More routes to Philadelphia and to Knoxville, TN

Looking for more options? Here you can see the most popular routes to Philadelphia and to Knoxville, TN. Simply click on a connection, and you’ll find all the details about the route!

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