What is the best way to travel from Knoxville, TN to Philadelphia?
Looking for a trip? Compare all the available Flights and Buses for the journey to Philadelphia from Knoxville, TN. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 1 available companies to find your perfect trip!
What is the cheapest way to reach Philadelphia from Knoxville, TN?
You can get to Philadelphia with just $64 by taking a Flight from Allegiant Air, but you can find many more cheap offers: we have selected the best ones for next few days here for you.
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Greyhound US16h 45m010:40 PMKnoxville, TNKnoxville Area Transit Bus Stop3:25 PMPhiladelphiaCentral Bus Station0EconomyA Bus from Greyhound US goes from Knoxville Area Transit Bus Stop, Knoxville, TN (USA) at 11/5/2026 10:40:00 PM to Central Bus Station, Philadelphia (USA) arriving at 11/6/2026 3:25:00 PM. 50 Economy ticket for $80 per person are available. Travel duration is 16h 45m
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Allegiant Air21h 8m09:28 PMKnoxville AirportKnoxville Airport6:36 PMPhiladelphia AirportPhiladelphia Airport0EconomyA Flight from Allegiant Air goes from Knoxville Airport, Knoxville Airport (USA) at 11/5/2026 9:28:00 PM to Philadelphia Airport, Philadelphia Airport (USA) arriving at 11/6/2026 6:36:00 PM. 50 Economy ticket for $128 per person are available. Travel duration is 21h 8m
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Allegiant Air27h 1m09:28 PMKnoxville AirportKnoxville Airport12:29 AMPhiladelphia AirportPhiladelphia Airport0EconomyA Flight from Allegiant Air goes from Knoxville Airport, Knoxville Airport (USA) at 11/5/2026 9:28:00 PM to Philadelphia Airport, Philadelphia Airport (USA) arriving at 11/7/2026 12:29:00 AM. 50 Economy ticket for $152 per person are available. Travel duration is 27h 1m
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Allegiant Air15h 6m09:28 PMKnoxville AirportKnoxville Airport12:34 PMPhiladelphia AirportPhiladelphia Airport0EconomyA Flight from Allegiant Air goes from Knoxville Airport, Knoxville Airport (USA) at 11/5/2026 9:28:00 PM to Philadelphia Airport, Philadelphia Airport (USA) arriving at 11/6/2026 12:34:00 PM. 50 Economy ticket for $153 per person are available. Travel duration is 15h 6m
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Allegiant Air22h 2m09:28 PMKnoxville AirportKnoxville Airport7:30 PMPhiladelphia AirportPhiladelphia Airport0EconomyA Flight from Allegiant Air goes from Knoxville Airport, Knoxville Airport (USA) at 11/5/2026 9:28:00 PM to Philadelphia Airport, Philadelphia Airport (USA) arriving at 11/6/2026 7:30:00 PM. 50 Economy ticket for $154 per person are available. Travel duration is 22h 2m
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Allegiant Air16h 48m06:33 PMKnoxville AirportKnoxville Airport11:21 AMPhiladelphia AirportPhiladelphia Airport0EconomyA Flight from Allegiant Air goes from Knoxville Airport, Knoxville Airport (USA) at 11/5/2026 6:33:00 PM to Philadelphia Airport, Philadelphia Airport (USA) arriving at 11/6/2026 11:21:00 AM. 50 Economy ticket for $158 per person are available. Travel duration is 16h 48m
Cheapest Buses Thursday
Cheapest Flights Thursday
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Allegiant Air1h 50m01:17 PMKnoxville AirportKnoxville Airport3:07 PMPhiladelphia AirportPhiladelphia Airport0EconomyA Flight from Allegiant Air goes from Knoxville Airport, Knoxville Airport (USA) at 11/6/2026 1:17:00 PM to Philadelphia Airport, Philadelphia Airport (USA) arriving at 11/6/2026 3:07:00 PM. 50 Economy ticket for $64 per person are available. Travel duration is 1h 50m
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Allegiant Air10h 1m08:35 AMKnoxville AirportKnoxville Airport6:36 PMPhiladelphia AirportPhiladelphia Airport0EconomyA Flight from Allegiant Air goes from Knoxville Airport, Knoxville Airport (USA) at 11/6/2026 8:35:00 AM to Philadelphia Airport, Philadelphia Airport (USA) arriving at 11/6/2026 6:36:00 PM. 50 Economy ticket for $142 per person are available. Travel duration is 10h 1m
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Allegiant Air15h 54m08:35 AMKnoxville AirportKnoxville Airport12:29 AMPhiladelphia AirportPhiladelphia Airport0EconomyA Flight from Allegiant Air goes from Knoxville Airport, Knoxville Airport (USA) at 11/6/2026 8:35:00 AM to Philadelphia Airport, Philadelphia Airport (USA) arriving at 11/7/2026 12:29:00 AM. 50 Economy ticket for $167 per person are available. Travel duration is 15h 54m
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United Airlines11h 2m06:45 AMKnoxville AirportKnoxville Airport5:47 PMPhiladelphia AirportPhiladelphia Airport0EconomyA Flight from United Airlines goes from Knoxville Airport, Knoxville Airport (USA) at 11/6/2026 6:45:00 AM to Philadelphia Airport, Philadelphia Airport (USA) arriving at 11/6/2026 5:47:00 PM. 50 Economy ticket for $424 per person are available. Travel duration is 11h 2m
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United Airlines28h 37m07:00 AMKnoxville AirportKnoxville Airport11:37 AMPhiladelphia AirportPhiladelphia Airport0EconomyA Flight from United Airlines goes from Knoxville Airport, Knoxville Airport (USA) at 11/6/2026 7:00:00 AM to Philadelphia Airport, Philadelphia Airport (USA) arriving at 11/7/2026 11:37:00 AM. 50 Economy ticket for $431 per person are available. Travel duration is 28h 37m
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Greyhound US16h 45m010:40 PMKnoxville, TNKnoxville Area Transit Bus Stop3:25 PMPhiladelphiaCentral Bus Station0EconomyA Bus from Greyhound US goes from Knoxville Area Transit Bus Stop, Knoxville, TN (USA) at 11/6/2026 10:40:00 PM to Central Bus Station, Philadelphia (USA) arriving at 11/7/2026 3:25:00 PM. 50 Economy ticket for $97 per person are available. Travel duration is 16h 45m
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Greyhound US16h 45m010:40 PMKnoxville, TNGreyhound Bus Station3:25 PMPhiladelphiaSpring Garden St Station0EconomyA Bus from Greyhound US goes from Greyhound Bus Station, Knoxville, TN (USA) at 11/6/2026 10:40:00 PM to Spring Garden St Station, Philadelphia (USA) arriving at 11/7/2026 3:25:00 PM. 50 Economy ticket for $101 per person are available. Travel duration is 16h 45m
Cheapest Flights Friday
Cheapest Buses Friday
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Greyhound US16h 45m010:40 PMKnoxville, TNKnoxville Area Transit Bus Stop3:25 PMPhiladelphiaCentral Bus Station0EconomyA Bus from Greyhound US goes from Knoxville Area Transit Bus Stop, Knoxville, TN (USA) at 11/7/2026 10:40:00 PM to Central Bus Station, Philadelphia (USA) arriving at 11/8/2026 3:25:00 PM. 50 Economy ticket for $82 per person are available. Travel duration is 16h 45m
Cheapest Buses Saturday
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Greyhound US16h 45m010:40 PMKnoxville, TNKnoxville Area Transit Bus Stop3:25 PMPhiladelphiaCentral Bus Station0EconomyA Bus from Greyhound US goes from Knoxville Area Transit Bus Stop, Knoxville, TN (USA) at 11/8/2026 10:40:00 PM to Central Bus Station, Philadelphia (USA) arriving at 11/9/2026 3:25:00 PM. 50 Economy ticket for $93 per person are available. Travel duration is 16h 45m
Cheapest Buses Sunday
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Greyhound US16h 45m010:40 PMKnoxville, TNKnoxville Area Transit Bus Stop3:25 PMPhiladelphiaCentral Bus Station0EconomyA Bus from Greyhound US goes from Knoxville Area Transit Bus Stop, Knoxville, TN (USA) at 11/10/2026 10:40:00 PM to Central Bus Station, Philadelphia (USA) arriving at 11/11/2026 3:25:00 PM. 50 Economy ticket for $89 per person are available. Travel duration is 16h 45m
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Greyhound US16h 45m010:40 PMKnoxville, TNGreyhound Bus Station3:25 PMPhiladelphiaSpring Garden St Station0EconomyA Bus from Greyhound US goes from Greyhound Bus Station, Knoxville, TN (USA) at 11/10/2026 10:40:00 PM to Spring Garden St Station, Philadelphia (USA) arriving at 11/11/2026 3:25:00 PM. 50 Economy ticket for $93 per person are available. Travel duration is 16h 45m
Cheapest Buses Tuesday
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Greyhound US16h 45m010:40 PMKnoxville, TNKnoxville Area Transit Bus Stop3:25 PMPhiladelphiaCentral Bus Station0EconomyA Bus from Greyhound US goes from Knoxville Area Transit Bus Stop, Knoxville, TN (USA) at 11/11/2026 10:40:00 PM to Central Bus Station, Philadelphia (USA) arriving at 11/12/2026 3:25:00 PM. 50 Economy ticket for $90 per person are available. Travel duration is 16h 45m
Cheapest Buses Wednesday
What are the fastest trips from Knoxville, TN to Philadelphia?
You can get to Philadelphia from Knoxville, TN in just 1h 50m with a Flight from Allegiant Air. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.
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Allegiant Air15h 6m09:28 PMKnoxville AirportKnoxville Airport12:34 PMPhiladelphia AirportPhiladelphia Airport0EconomyA Flight from Allegiant Air goes from Knoxville Airport, Knoxville Airport (USA) at 11/5/2026 9:28:00 PM to Philadelphia Airport, Philadelphia Airport (USA) arriving at 11/6/2026 12:34:00 PM. 50 Economy ticket for $153 per person are available. Travel duration is 15h 6m
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Allegiant Air16h 48m06:33 PMKnoxville AirportKnoxville Airport11:21 AMPhiladelphia AirportPhiladelphia Airport0EconomyA Flight from Allegiant Air goes from Knoxville Airport, Knoxville Airport (USA) at 11/5/2026 6:33:00 PM to Philadelphia Airport, Philadelphia Airport (USA) arriving at 11/6/2026 11:21:00 AM. 50 Economy ticket for $158 per person are available. Travel duration is 16h 48m
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Allegiant Air21h 8m09:28 PMKnoxville AirportKnoxville Airport6:36 PMPhiladelphia AirportPhiladelphia Airport0EconomyA Flight from Allegiant Air goes from Knoxville Airport, Knoxville Airport (USA) at 11/5/2026 9:28:00 PM to Philadelphia Airport, Philadelphia Airport (USA) arriving at 11/6/2026 6:36:00 PM. 50 Economy ticket for $128 per person are available. Travel duration is 21h 8m
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Allegiant Air22h 2m09:28 PMKnoxville AirportKnoxville Airport7:30 PMPhiladelphia AirportPhiladelphia Airport0EconomyA Flight from Allegiant Air goes from Knoxville Airport, Knoxville Airport (USA) at 11/5/2026 9:28:00 PM to Philadelphia Airport, Philadelphia Airport (USA) arriving at 11/6/2026 7:30:00 PM. 50 Economy ticket for $154 per person are available. Travel duration is 22h 2m
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Allegiant Air27h 1m09:28 PMKnoxville AirportKnoxville Airport12:29 AMPhiladelphia AirportPhiladelphia Airport0EconomyA Flight from Allegiant Air goes from Knoxville Airport, Knoxville Airport (USA) at 11/5/2026 9:28:00 PM to Philadelphia Airport, Philadelphia Airport (USA) arriving at 11/7/2026 12:29:00 AM. 50 Economy ticket for $152 per person are available. Travel duration is 27h 1m
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Greyhound US16h 45m010:40 PMKnoxville, TNKnoxville Area Transit Bus Stop3:25 PMPhiladelphiaCentral Bus Station0EconomyA Bus from Greyhound US goes from Knoxville Area Transit Bus Stop, Knoxville, TN (USA) at 11/5/2026 10:40:00 PM to Central Bus Station, Philadelphia (USA) arriving at 11/6/2026 3:25:00 PM. 50 Economy ticket for $80 per person are available. Travel duration is 16h 45m
Fastest Flights Thursday
Fastest Buses Thursday
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Allegiant Air1h 50m01:17 PMKnoxville AirportKnoxville Airport3:07 PMPhiladelphia AirportPhiladelphia Airport0EconomyA Flight from Allegiant Air goes from Knoxville Airport, Knoxville Airport (USA) at 11/6/2026 1:17:00 PM to Philadelphia Airport, Philadelphia Airport (USA) arriving at 11/6/2026 3:07:00 PM. 50 Economy ticket for $64 per person are available. Travel duration is 1h 50m
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Allegiant Air10h 1m08:35 AMKnoxville AirportKnoxville Airport6:36 PMPhiladelphia AirportPhiladelphia Airport0EconomyA Flight from Allegiant Air goes from Knoxville Airport, Knoxville Airport (USA) at 11/6/2026 8:35:00 AM to Philadelphia Airport, Philadelphia Airport (USA) arriving at 11/6/2026 6:36:00 PM. 50 Economy ticket for $142 per person are available. Travel duration is 10h 1m
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United Airlines11h 2m06:45 AMKnoxville AirportKnoxville Airport5:47 PMPhiladelphia AirportPhiladelphia Airport0EconomyA Flight from United Airlines goes from Knoxville Airport, Knoxville Airport (USA) at 11/6/2026 6:45:00 AM to Philadelphia Airport, Philadelphia Airport (USA) arriving at 11/6/2026 5:47:00 PM. 50 Economy ticket for $424 per person are available. Travel duration is 11h 2m
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Allegiant Air15h 54m08:35 AMKnoxville AirportKnoxville Airport12:29 AMPhiladelphia AirportPhiladelphia Airport0EconomyA Flight from Allegiant Air goes from Knoxville Airport, Knoxville Airport (USA) at 11/6/2026 8:35:00 AM to Philadelphia Airport, Philadelphia Airport (USA) arriving at 11/7/2026 12:29:00 AM. 50 Economy ticket for $167 per person are available. Travel duration is 15h 54m
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United Airlines28h 37m07:00 AMKnoxville AirportKnoxville Airport11:37 AMPhiladelphia AirportPhiladelphia Airport0EconomyA Flight from United Airlines goes from Knoxville Airport, Knoxville Airport (USA) at 11/6/2026 7:00:00 AM to Philadelphia Airport, Philadelphia Airport (USA) arriving at 11/7/2026 11:37:00 AM. 50 Economy ticket for $431 per person are available. Travel duration is 28h 37m
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Greyhound US16h 45m010:40 PMKnoxville, TNKnoxville Area Transit Bus Stop3:25 PMPhiladelphiaCentral Bus Station0EconomyA Bus from Greyhound US goes from Knoxville Area Transit Bus Stop, Knoxville, TN (USA) at 11/6/2026 10:40:00 PM to Central Bus Station, Philadelphia (USA) arriving at 11/7/2026 3:25:00 PM. 50 Economy ticket for $97 per person are available. Travel duration is 16h 45m
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Greyhound US16h 45m010:40 PMKnoxville, TNGreyhound Bus Station3:25 PMPhiladelphiaSpring Garden St Station0EconomyA Bus from Greyhound US goes from Greyhound Bus Station, Knoxville, TN (USA) at 11/6/2026 10:40:00 PM to Spring Garden St Station, Philadelphia (USA) arriving at 11/7/2026 3:25:00 PM. 50 Economy ticket for $101 per person are available. Travel duration is 16h 45m
Fastest Flights Friday
Fastest Buses Friday
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Greyhound US16h 45m010:40 PMKnoxville, TNKnoxville Area Transit Bus Stop3:25 PMPhiladelphiaCentral Bus Station0EconomyA Bus from Greyhound US goes from Knoxville Area Transit Bus Stop, Knoxville, TN (USA) at 11/7/2026 10:40:00 PM to Central Bus Station, Philadelphia (USA) arriving at 11/8/2026 3:25:00 PM. 50 Economy ticket for $82 per person are available. Travel duration is 16h 45m
Fastest Buses Saturday
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Greyhound US16h 45m010:40 PMKnoxville, TNKnoxville Area Transit Bus Stop3:25 PMPhiladelphiaCentral Bus Station0EconomyA Bus from Greyhound US goes from Knoxville Area Transit Bus Stop, Knoxville, TN (USA) at 11/8/2026 10:40:00 PM to Central Bus Station, Philadelphia (USA) arriving at 11/9/2026 3:25:00 PM. 50 Economy ticket for $93 per person are available. Travel duration is 16h 45m
Fastest Buses Sunday
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Greyhound US16h 45m010:40 PMKnoxville, TNKnoxville Area Transit Bus Stop3:25 PMPhiladelphiaCentral Bus Station0EconomyA Bus from Greyhound US goes from Knoxville Area Transit Bus Stop, Knoxville, TN (USA) at 11/10/2026 10:40:00 PM to Central Bus Station, Philadelphia (USA) arriving at 11/11/2026 3:25:00 PM. 50 Economy ticket for $89 per person are available. Travel duration is 16h 45m
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Greyhound US16h 45m010:40 PMKnoxville, TNGreyhound Bus Station3:25 PMPhiladelphiaSpring Garden St Station0EconomyA Bus from Greyhound US goes from Greyhound Bus Station, Knoxville, TN (USA) at 11/10/2026 10:40:00 PM to Spring Garden St Station, Philadelphia (USA) arriving at 11/11/2026 3:25:00 PM. 50 Economy ticket for $93 per person are available. Travel duration is 16h 45m
Fastest Buses Tuesday
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Greyhound US16h 45m010:40 PMKnoxville, TNKnoxville Area Transit Bus Stop3:25 PMPhiladelphiaCentral Bus Station0EconomyA Bus from Greyhound US goes from Knoxville Area Transit Bus Stop, Knoxville, TN (USA) at 11/11/2026 10:40:00 PM to Central Bus Station, Philadelphia (USA) arriving at 11/12/2026 3:25:00 PM. 50 Economy ticket for $90 per person are available. Travel duration is 16h 45m
Fastest Buses Wednesday
Here you will find all operators and timetables for a
Bus from Knoxville, TN to Philadelphia
What are the most popular stations in Knoxville, TN and Philadelphia?
In Knoxville, TN, you will usually depart from Knoxville Area Transit Bus Stop, Greyhound Bus Station or Transit Center, while in Philadelphia you will be arriving at 30th Street Station, The Gallery or 520 N Christopher Columbus Blvd. Bus Stop, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to Philadelphia from Knoxville, TN? With 3 connections between 1 Flight and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Knoxville, TN and Philadelphia, you can pay as low as $64 with a Flight from Allegiant Air.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Allegiant Air: you will get to Philadelphia in just 1h 50m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Knoxville, TN and Philadelphia are Greyhound US, Allegiant Air and United Airlines, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Knoxville, TN and Philadelphia is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Wildwood, TN or to Millbourne, PA, and look at flights from Knoxville Airport, and landing at Greater Wilmington Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Knoxville, TN to Philadelphia?
The most popular companies between Knoxville, TN and Philadelphia, are Greyhound US, Allegiant Air and United Airlines. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: Greyhound US
Airlines: Allegiant Air and United Airlines
All you need to know when you travel from Knoxville, TN to Philadelphia
Check all information on comfort and services on all modes of transports from Knoxville, TN to Philadelphia. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Knoxville, TN to Philadelphia
How can I reach Philadelphia from Knoxville, TN?
Every day, there are on average 3 connections between Flight and Bus, with which you can get to Philadelphia from Knoxville, TN.
How far is Philadelphia from Knoxville, TN?
The distance between Knoxville, TN and Philadelphia is 549.6 miles.
What is the most ecofriendly mode of transport between Knoxville, TN and Philadelphia?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 24 kgs of CO2, a train 31 kgs, a car 150 kgs, and a flight 218 kgs.
What is the cheapest mode of transport from Knoxville, TN to Philadelphia?
You can get to Philadelphia with just $64 by taking a Flight from Allegiant Air.
What is the fastest way to get from Knoxville, TN to Philadelphia?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Philadelphia in just 1h 50m with a Flight from Allegiant Air.
More routes to Knoxville, TN and to Philadelphia
Looking for more options? Here you can see the most popular routes to Knoxville, TN and to Philadelphia. Simply click on a connection, and you’ll find all the details about the route!
