How to get from Indianapolis to Knoxville, TN

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What is the best way to travel from Indianapolis to Knoxville, TN?

Looking for a trip? Compare all the available Flights and Buses for the journey to Knoxville, TN from Indianapolis. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 1 available companies to find your perfect trip!
Bus is the cheapest, while Flight is the fastest way on this route
Transport type
Travel time
Cheapest price
Average price
Daily departures
Bus
10h 20m
$57
$85
4
Flight
3h 59m
$120
$250
40

What is the cheapest way to reach Knoxville, TN from Indianapolis?

You can get to Knoxville, TN with just $57 by taking a Bus from Greyhound US, but you can find many more cheap offers: we have selected the best ones for next few days here for you.

Monday
from $202
Tuesday
Wednesday
from $223
Thursday
from $57
Friday
Saturday
from $145
Sunday
from $76

    Cheapest Flights Monday

  • Allegiant Air
    13h 6m
    0
    7:30 AM
    Indianapolis Airport
    Indianapolis Airport
    8:36 PM
    Knoxville Airport
    Knoxville Airport
    0
    Allegiant Air
    Economy
    from $202
  • Frontier Airlines
    16h 37m
    0
    7:33 PM
    Indianapolis Airport
    Indianapolis Airport
    12:10 PM
    Knoxville Airport
    Knoxville Airport
    0
    Frontier Airlines
    Economy
    from $271
  • United Airlines
    6h 9m
    0
    7:15 AM
    Indianapolis Airport
    Indianapolis Airport
    1:24 PM
    Knoxville Airport
    Knoxville Airport
    0
    United Airlines
    Economy
    from $274
  • Skyscanner
    4h 19m
    0
    9:05 AM
    Indianapolis Airport
    Indianapolis Airport
    1:24 PM
    Knoxville Airport
    Knoxville Airport
    0
    Skyscanner
    Economy
    from $274
  • Spirit Airlines
    6h 50m
    0
    10:38 AM
    Indianapolis Airport
    Indianapolis Airport
    5:28 PM
    Knoxville Airport
    Knoxville Airport
    0
    Spirit Airlines
    Economy
    from $406

    Cheapest Flights Wednesday

  • Spirit Airlines
    10h 47m
    0
    5:10 AM
    Indianapolis Airport
    Indianapolis Airport
    3:57 PM
    Knoxville Airport
    Knoxville Airport
    0
    Spirit Airlines
    Economy
    from $223
  • United Airlines
    4h 39m
    0
    8:45 AM
    Indianapolis Airport
    Indianapolis Airport
    1:24 PM
    Knoxville Airport
    Knoxville Airport
    0
    United Airlines
    Economy
    from $274
  • United Airlines
    6h 52m
    0
    2:00 PM
    Indianapolis Airport
    Indianapolis Airport
    8:52 PM
    Knoxville Airport
    Knoxville Airport
    0
    United Airlines
    Economy
    from $274
  • Skyscanner
    3h 59m
    0
    9:25 AM
    Indianapolis Airport
    Indianapolis Airport
    1:24 PM
    Knoxville Airport
    Knoxville Airport
    0
    Skyscanner
    Economy
    from $274
  • Skyscanner
    4h 49m
    0
    10:00 AM
    Indianapolis Airport
    Indianapolis Airport
    2:49 PM
    Knoxville Airport
    Knoxville Airport
    0
    Skyscanner
    Economy
    from $274

    Cheapest Buses Thursday

  • Greyhound US
    10h 20m
    0
    9:10 AM
    Indianapolis
    Central Bus Station
    7:30 PM
    Knoxville, TN
    Knoxville Area Transit Bus Stop
    0
    Greyhound US
    Economy
    $57
  • Greyhound US
    11h 15m
    0
    11:25 AM
    Indianapolis
    Central Bus Station
    10:40 PM
    Knoxville, TN
    Knoxville Area Transit Bus Stop
    0
    Greyhound US
    Economy
    $57
  • Greyhound US
    10h 20m
    0
    9:10 AM
    Indianapolis
    Central Bus Station
    7:30 PM
    Knoxville, TN
    Greyhound Bus Station
    0
    Greyhound US
    Economy
    $61
  • Greyhound US
    11h 15m
    0
    11:25 AM
    Indianapolis
    Central Bus Station
    10:40 PM
    Knoxville, TN
    Greyhound Bus Station
    0
    Greyhound US
    Economy
    $61
  • Cheapest Flights Thursday

  • Allegiant Air
    14h 10m
    0
    9:00 AM
    Indianapolis Airport
    Indianapolis Airport
    11:10 PM
    Knoxville Airport
    Knoxville Airport
    0
    Allegiant Air
    Economy
    from $201
  • Spirit Airlines
    29h 10m
    0
    6:55 AM
    Indianapolis Airport
    Indianapolis Airport
    12:05 PM
    Knoxville Airport
    Knoxville Airport
    0
    Spirit Airlines
    Economy
    from $227
  • Frontier Airlines
    13h 39m
    0
    8:31 PM
    Indianapolis Airport
    Indianapolis Airport
    10:10 AM
    Knoxville Airport
    Knoxville Airport
    0
    Frontier Airlines
    Economy
    from $275
  • United Airlines
    6h 9m
    0
    7:15 AM
    Indianapolis Airport
    Indianapolis Airport
    1:24 PM
    Knoxville Airport
    Knoxville Airport
    0
    United Airlines
    Economy
    from $303
  • Skyscanner
    4h 32m
    0
    6:00 AM
    Indianapolis Airport
    Indianapolis Airport
    10:32 AM
    Knoxville Airport
    Knoxville Airport
    0
    Skyscanner
    Economy
    from $303

    Cheapest Buses Saturday

  • Greyhound US
    11h 15m
    0
    11:25 AM
    Indianapolis
    Central Bus Station
    10:40 PM
    Knoxville, TN
    Greyhound Bus Station
    0
    Greyhound US
    Economy
    $145
  • Greyhound US
    10h 20m
    0
    9:10 AM
    Indianapolis
    Central Bus Station
    7:30 PM
    Knoxville, TN
    Greyhound Bus Station
    0
    Greyhound US
    Economy
    $146

    Cheapest Buses Sunday

  • Greyhound US
    11h 15m
    0
    11:25 AM
    Indianapolis
    Central Bus Station
    10:40 PM
    Knoxville, TN
    Greyhound Bus Station
    0
    Greyhound US
    Economy
    $76
  • Greyhound US
    10h 20m
    0
    9:10 AM
    Indianapolis
    Central Bus Station
    7:30 PM
    Knoxville, TN
    Greyhound Bus Station
    0
    Greyhound US
    Economy
    $77
  • Cheapest Flights Sunday

  • Allegiant Air
    14h 10m
    0
    9:00 AM
    Indianapolis Airport
    Indianapolis Airport
    11:10 PM
    Knoxville Airport
    Knoxville Airport
    0
    Allegiant Air
    Economy
    from $120
  • Spirit Airlines
    12h 15m
    0
    10:38 AM
    Indianapolis Airport
    Indianapolis Airport
    10:53 PM
    Knoxville Airport
    Knoxville Airport
    0
    Spirit Airlines
    Economy
    from $136
  • Frontier Airlines
    12h 36m
    0
    9:34 PM
    Indianapolis Airport
    Indianapolis Airport
    10:10 AM
    Knoxville Airport
    Knoxville Airport
    0
    Frontier Airlines
    Economy
    from $149
  • Skyscanner
    4h 59m
    0
    9:50 AM
    Indianapolis Airport
    Indianapolis Airport
    2:49 PM
    Knoxville Airport
    Knoxville Airport
    0
    Skyscanner
    Economy
    from $272
  • United Airlines
    6h 52m
    0
    2:00 PM
    Indianapolis Airport
    Indianapolis Airport
    8:52 PM
    Knoxville Airport
    Knoxville Airport
    0
    United Airlines
    Economy
    from $272

What are the fastest trips from Indianapolis to Knoxville, TN?

You can get to Knoxville, TN from Indianapolis in just 3h 59m with a Flight from Skyscanner. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.

Monday
from 4h 19m
Tuesday
Wednesday
from 3h 59m
Thursday
from 4h 32m
Friday
Saturday
from 10h 20m
Sunday
from 4h 59m

    Fastest Flights Monday

  • Skyscanner
    4h 19m
    0
    9:05 AM
    Indianapolis Airport
    Indianapolis Airport
    1:24 PM
    Knoxville Airport
    Knoxville Airport
    0
    Skyscanner
    Economy
    from $274
  • United Airlines
    6h 9m
    0
    7:15 AM
    Indianapolis Airport
    Indianapolis Airport
    1:24 PM
    Knoxville Airport
    Knoxville Airport
    0
    United Airlines
    Economy
    from $274
  • Spirit Airlines
    6h 50m
    0
    10:38 AM
    Indianapolis Airport
    Indianapolis Airport
    5:28 PM
    Knoxville Airport
    Knoxville Airport
    0
    Spirit Airlines
    Economy
    from $406
  • Allegiant Air
    13h 6m
    0
    7:30 AM
    Indianapolis Airport
    Indianapolis Airport
    8:36 PM
    Knoxville Airport
    Knoxville Airport
    0
    Allegiant Air
    Economy
    from $202
  • Frontier Airlines
    16h 37m
    0
    7:33 PM
    Indianapolis Airport
    Indianapolis Airport
    12:10 PM
    Knoxville Airport
    Knoxville Airport
    0
    Frontier Airlines
    Economy
    from $271

    Fastest Flights Wednesday

  • Skyscanner
    3h 59m
    0
    9:25 AM
    Indianapolis Airport
    Indianapolis Airport
    1:24 PM
    Knoxville Airport
    Knoxville Airport
    0
    Skyscanner
    Economy
    from $274
  • United Airlines
    4h 39m
    0
    8:45 AM
    Indianapolis Airport
    Indianapolis Airport
    1:24 PM
    Knoxville Airport
    Knoxville Airport
    0
    United Airlines
    Economy
    from $274
  • Skyscanner
    4h 49m
    0
    10:00 AM
    Indianapolis Airport
    Indianapolis Airport
    2:49 PM
    Knoxville Airport
    Knoxville Airport
    0
    Skyscanner
    Economy
    from $274
  • United Airlines
    6h 52m
    0
    2:00 PM
    Indianapolis Airport
    Indianapolis Airport
    8:52 PM
    Knoxville Airport
    Knoxville Airport
    0
    United Airlines
    Economy
    from $274
  • Spirit Airlines
    10h 47m
    0
    5:10 AM
    Indianapolis Airport
    Indianapolis Airport
    3:57 PM
    Knoxville Airport
    Knoxville Airport
    0
    Spirit Airlines
    Economy
    from $223

    Fastest Flights Thursday

  • Skyscanner
    4h 32m
    0
    6:00 AM
    Indianapolis Airport
    Indianapolis Airport
    10:32 AM
    Knoxville Airport
    Knoxville Airport
    0
    Skyscanner
    Economy
    from $303
  • United Airlines
    6h 9m
    0
    7:15 AM
    Indianapolis Airport
    Indianapolis Airport
    1:24 PM
    Knoxville Airport
    Knoxville Airport
    0
    United Airlines
    Economy
    from $303
  • Frontier Airlines
    13h 39m
    0
    8:31 PM
    Indianapolis Airport
    Indianapolis Airport
    10:10 AM
    Knoxville Airport
    Knoxville Airport
    0
    Frontier Airlines
    Economy
    from $275
  • Allegiant Air
    14h 10m
    0
    9:00 AM
    Indianapolis Airport
    Indianapolis Airport
    11:10 PM
    Knoxville Airport
    Knoxville Airport
    0
    Allegiant Air
    Economy
    from $201
  • Spirit Airlines
    29h 10m
    0
    6:55 AM
    Indianapolis Airport
    Indianapolis Airport
    12:05 PM
    Knoxville Airport
    Knoxville Airport
    0
    Spirit Airlines
    Economy
    from $227
  • Fastest Buses Thursday

  • Greyhound US
    10h 20m
    0
    9:10 AM
    Indianapolis
    Central Bus Station
    7:30 PM
    Knoxville, TN
    Knoxville Area Transit Bus Stop
    0
    Greyhound US
    Economy
    $57
  • Greyhound US
    10h 20m
    0
    9:10 AM
    Indianapolis
    Central Bus Station
    7:30 PM
    Knoxville, TN
    Greyhound Bus Station
    0
    Greyhound US
    Economy
    $61
  • Greyhound US
    11h 15m
    0
    11:25 AM
    Indianapolis
    Central Bus Station
    10:40 PM
    Knoxville, TN
    Knoxville Area Transit Bus Stop
    0
    Greyhound US
    Economy
    $57
  • Greyhound US
    11h 15m
    0
    11:25 AM
    Indianapolis
    Central Bus Station
    10:40 PM
    Knoxville, TN
    Greyhound Bus Station
    0
    Greyhound US
    Economy
    $61

    Fastest Buses Saturday

  • Greyhound US
    10h 20m
    0
    9:10 AM
    Indianapolis
    Central Bus Station
    7:30 PM
    Knoxville, TN
    Greyhound Bus Station
    0
    Greyhound US
    Economy
    $146
  • Greyhound US
    11h 15m
    0
    11:25 AM
    Indianapolis
    Central Bus Station
    10:40 PM
    Knoxville, TN
    Greyhound Bus Station
    0
    Greyhound US
    Economy
    $145

    Fastest Flights Sunday

  • Skyscanner
    4h 59m
    0
    9:50 AM
    Indianapolis Airport
    Indianapolis Airport
    2:49 PM
    Knoxville Airport
    Knoxville Airport
    0
    Skyscanner
    Economy
    from $272
  • United Airlines
    6h 52m
    0
    2:00 PM
    Indianapolis Airport
    Indianapolis Airport
    8:52 PM
    Knoxville Airport
    Knoxville Airport
    0
    United Airlines
    Economy
    from $272
  • Spirit Airlines
    12h 15m
    0
    10:38 AM
    Indianapolis Airport
    Indianapolis Airport
    10:53 PM
    Knoxville Airport
    Knoxville Airport
    0
    Spirit Airlines
    Economy
    from $136
  • Frontier Airlines
    12h 36m
    0
    9:34 PM
    Indianapolis Airport
    Indianapolis Airport
    10:10 AM
    Knoxville Airport
    Knoxville Airport
    0
    Frontier Airlines
    Economy
    from $149
  • Allegiant Air
    14h 10m
    0
    9:00 AM
    Indianapolis Airport
    Indianapolis Airport
    11:10 PM
    Knoxville Airport
    Knoxville Airport
    0
    Allegiant Air
    Economy
    from $120
  • Fastest Buses Sunday

  • Greyhound US
    10h 20m
    0
    9:10 AM
    Indianapolis
    Central Bus Station
    7:30 PM
    Knoxville, TN
    Greyhound Bus Station
    0
    Greyhound US
    Economy
    $77
  • Greyhound US
    11h 15m
    0
    11:25 AM
    Indianapolis
    Central Bus Station
    10:40 PM
    Knoxville, TN
    Greyhound Bus Station
    0
    Greyhound US
    Economy
    $76
Here you will find all operators and timetables for a Bus from Indianapolis to Knoxville, TN

What are the most popular stations in Indianapolis and Knoxville, TN?

In Indianapolis, you will usually depart from Central Bus Station, Greyhound Bus Station or Downtown Transit Center, while in Knoxville, TN you will be arriving at Knoxville Area Transit Bus Stop, Greyhound Bus Station or Transit Center, but there are many more stops to explore in both locations.

How do I decide? Some tips and tricks from our experience

Are you having trouble deciding on how to get to Knoxville, TN from Indianapolis? With 5 connections between 1 Flight and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.

Look for the lowest price

Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Indianapolis and Knoxville, TN, you can pay as low as $57 with a Bus from Greyhound US.

Travel duration

Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Skyscanner: you will get to Knoxville, TN in just 3h 59m.

Comfort makes all the difference

You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Indianapolis and Knoxville, TN are Greyhound US, United Airlines and Skyscanner, but be sure to check what they have to offer!

Save money with deals, and always compare

One last tip? Even if you live in Indianapolis and Knoxville, TN is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Beech Grove, IN or to Wildwood, TN, and look at flights from Indianapolis Airport, and landing at Knoxville Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!

Which companies offer a trip from Indianapolis to Knoxville, TN?

The most popular companies between Indianapolis and Knoxville, TN, are Greyhound US, United Airlines and Skyscanner. Be sure to check their seat class offers and the amenities that they provide.

Bus companies: Greyhound US

Airlines: United Airlines, Skyscanner, Spirit Airlines and 2 more.

All you need to know when you travel from Indianapolis to Knoxville, TN

Check all information on comfort and services on all modes of transports from Indianapolis to Knoxville, TN. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.

FAQs about the trip from Indianapolis to Knoxville, TN

How can I reach Knoxville, TN from Indianapolis?

Every day, there are on average 5 connections between Flight and Bus, with which you can get to Knoxville, TN from Indianapolis.

How far is Knoxville, TN from Indianapolis?

The distance between Indianapolis and Knoxville, TN is 289.8 miles.

What is the most ecofriendly mode of transport between Indianapolis and Knoxville, TN?

Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance. On this particular route, a bus will emit, per person, a total of 13 kgs of CO2, a train 16 kgs, a car 79 kgs, and a flight 115 kgs.

What is the cheapest mode of transport from Indianapolis to Knoxville, TN?

You can get to Knoxville, TN with just $57 by taking a Bus from Greyhound US.

What is the fastest way to get from Indianapolis to Knoxville, TN?

While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to Knoxville, TN in just 3h 59m with a Flight from Skyscanner.

More routes to Indianapolis and to Knoxville, TN

Looking for more options? Here you can see the most popular routes to Indianapolis and to Knoxville, TN. Simply click on a connection, and you’ll find all the details about the route!

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