Which bus from Indianapolis to Knoxville, TN is the cheapest?

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Compare all timetables for the bus from Indianapolis to Knoxville, TN

Here is a selection of the cheapest bus trips from the schedule from Indianapolis to Knoxville, TN from various bus operators like Greyhound US for the next days.

today
$73
tomorrow
$76
Thursday
Friday
$77
Saturday
$75
Sunday
Monday

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 10h 20m 9:10 AM Indianapolis Central Bus Station 7:30 PM Knoxville, TN Knoxville Area Transit Bus Stop  Economy $73
Greyhound US 11h 15m 11:25 AM Indianapolis Central Bus Station 10:40 PM Knoxville, TN Knoxville Area Transit Bus Stop  Economy $73

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 11h 15m 11:25 AM Indianapolis Central Bus Station 10:40 PM Knoxville, TN Greyhound Bus Station  Economy $76
Greyhound US 10h 20m 9:10 AM Indianapolis Central Bus Station 7:30 PM Knoxville, TN Greyhound Bus Station  Economy $77

Cheapest bus trips Friday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 11h 25m 11:15 AM Indianapolis Central Bus Station 10:40 PM Knoxville, TN Greyhound Bus Station  Economy $77
Greyhound US 10h 20m 9:10 AM Indianapolis Central Bus Station 7:30 PM Knoxville, TN Greyhound Bus Station  Economy $86
  • Did you know that if you travel from Indianapolis to Knoxville, TN via Louisville, KY, you can save more than $8? You can find the corresponding connections below.
    • Greyhound US
      11h 15m
      0
      11:25 AM
      Indianapolis
      Central Bus Station
      1:25 PM
      Louisville, KY
      Greyhound Bus Station
      0
      Greyhound US
      Economy
      $20
      • Waiting Time 0h 40m
    • Greyhound US
      8h 35m
      0
      2:05 PM
      Louisville, KY
      Greyhound Bus Station
      10:40 PM
      Knoxville, TN
      Greyhound Bus Station
      0
      Greyhound US
      Economy
      $49
    Travel time is 0h 55m longer, but you will save $8

Cheapest bus trips Saturday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 11h 25m 11:15 AM Indianapolis Central Bus Station 10:40 PM Knoxville, TN Knoxville Area Transit Bus Stop  Economy $75
Greyhound US 10h 20m 9:10 AM Indianapolis Central Bus Station 7:30 PM Knoxville, TN Knoxville Area Transit Bus Stop  Economy $76

Best Price Offer: The price for the cheapest bus from Indianapolis to Knoxville, TN is $64 on 4/13/2026. Flexible travelers save on ticket prices.


Facts about the bus from Indianapolis to Knoxville, TN

Compare all providers like Greyhound US that travel 2 times every day by bus from Indianapolis to Knoxville, TN in one click! Book your bus ticket from Indianapolis to Knoxville, TN starting from $64!

Cheapest Bus $64
Fastest Bus 10h 20m
Earliest Bus 9:10 AM
Latest Bus 11:15 AM
Daily Bus Routes 2 Ø
Distance 289.8 miles
Bus Companies Greyhound US

Cheapest bus connections from Indianapolis to Knoxville, TN

Every day, 2 buses from 1 bus companies leave Indianapolis for Knoxville, TN: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 03/24/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 03/22
Monday 03/23
Tuesday 03/24
$73
Wednesday 03/25
$76
Thursday 03/26
Friday 03/27
$77
Saturday 03/28
$75
Sunday 03/29
Monday 03/30
Tuesday 03/31
$77
Wednesday 04/01
$73
Thursday 04/02
Friday 04/03
Saturday 04/04
$65
Sunday 04/05
$72
Monday 04/06
Tuesday 04/07
Wednesday 04/08
$72
Thursday 04/09
$66
Friday 04/10
$73
Saturday 04/11
$69
Sunday 04/12
$76
Monday 04/13
$64
Tuesday 04/14
Wednesday 04/15
$71
Thursday 04/16
$67
Friday 04/17
$77
Saturday 04/18

How to save money travelling from Indianapolis to Knoxville, TN

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Indianapolis to Knoxville, TN in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Indianapolis to Knoxville, TN, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Indianapolis to Knoxville, TN are also emptier.

Beloved bus companies from Indianapolis to Knoxville, TN

These are the most booked bus companies between Indianapolis to Knoxville, TN from our users.

Greyhound US from Indianapolis to Knoxville, TN

Greyhound US

Here you will find the key facts about the Greyhound US bus route Indianapolis to Knoxville, TN:

Cheapest Price $73
Fastest Bus 10h 20m
Earliest Bus 9:10 AM
Last Bus 11:15 AM
Daily Connections 2 Ø
Found on 2/25/2026

All bus stations and stops in Indianapolis and Knoxville, TN

In the map below, you can see where to find all bus stations in Indianapolis and Knoxville, TN.

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Indianapolis to Knoxville, TN? Compare all modes of transports from Indianapolis to Knoxville, TN.

Service and Comfort on the bus from Indianapolis to Knoxville, TN

Want to know which seat classes are available on the buses from Indianapolis to Knoxville, TN? Or which bus companies serve the route Indianapolis to Knoxville, TN? Below you will find answers to your questions.

FAQs about the Indianapolis to Knoxville, TN bus

How much does a Indianapolis Knoxville, TN bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $64 and takes 10h 20m to reach Knoxville, TN. Compare offers to save money!

How much could I save by comparing buses from Indianapolis to Knoxville, TN?

This route is offered by 1 companies with a range of ticket prices between $64 and $86. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Knoxville, TN.

On average, how many connections are available from Indianapolis to Knoxville, TN each day?

Every day, the Indianapolis to Knoxville, TN bus route is served by approximately 2 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Indianapolis to Knoxville, TN take?

The fastest bus from Indianapolis to Knoxville, TN is offered by Greyhound US and takes 10h 20m. Bus tickets for this connection cost $73. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Indianapolis to Knoxville, TN?

The earliest bus arriving in Knoxville, TN from Indianapolis starts at 9:10 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Indianapolis to Knoxville, TN?

The latest bus trip departing from Indianapolis for Knoxville, TN starts at 11:15 AM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Indianapolis Knoxville, TN route?

When traveling by bus from Indianapolis to Knoxville, TN, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Indianapolis and Knoxville, TN?

You can check all the direct connections between Indianapolis and Knoxville, TN by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Indianapolis to Knoxville, TN bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Indianapolis Knoxville, TN bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Indianapolis Knoxville, TN bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Indianapolis to Knoxville, TN on your planned travel date.

How does CheckMyBus find the best bus deals from Indianapolis to Knoxville, TN?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 2 daily trips between Indianapolis and Knoxville, TN. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Indianapolis to Knoxville, TN?

Prices and availability for 2 trips between Indianapolis and Knoxville, TN change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Indianapolis to Knoxville, TN

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Indianapolis and to Knoxville, TN

Here’s an overview of the most popular bus routes to Indianapolis and to Knoxville, TN. Simply click on the connection of your choice, and you will find all the details about your bus route!
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