Compare all timetables for the bus from Chicago to Knoxville, TN
Here is a selection of the cheapest bus trips from the schedule from Chicago to Knoxville, TN from various bus operators like Greyhound US for the next days.
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 23h 10m | 10:30 PM | Chicago | Downtown Bus Station | 10:40 PM | Knoxville, TN | Greyhound Bus Station | Economy | $104 |
A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 12/6/2025 10:30:00 PM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 12/7/2025 10:40:00 PM. 50 Economy ticket for $104 per person are available. Travel duration is 23h 10m
|
||
| Greyhound US | 19h 45m | 10:10 PM | Chicago | Downtown Bus Station | 6:55 PM | Knoxville, TN | Greyhound Bus Station | Economy | $112 |
A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 12/6/2025 10:10:00 PM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 12/7/2025 6:55:00 PM. 50 Economy ticket for $112 per person are available. Travel duration is 19h 45m
|
||
| Greyhound US | 15h 30m | 6:10 AM | Chicago | Downtown Bus Station | 10:40 PM | Knoxville, TN | Greyhound Bus Station | Economy | $114 |
A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 12/6/2025 6:10:00 AM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 12/6/2025 10:40:00 PM. 50 Economy ticket for $114 per person are available. Travel duration is 15h 30m
|
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 15h 30m | 6:10 AM | Chicago | Downtown Bus Station | 10:40 PM | Knoxville, TN | Greyhound Bus Station | Economy | $95 |
A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 12/8/2025 6:10:00 AM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 12/8/2025 10:40:00 PM. 50 Economy ticket for $95 per person are available. Travel duration is 15h 30m
|
||
| Greyhound US | 23h 10m | 10:30 PM | Chicago | Downtown Bus Station | 10:40 PM | Knoxville, TN | Greyhound Bus Station | Economy | $95 |
A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 12/8/2025 10:30:00 PM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 12/9/2025 10:40:00 PM. 50 Economy ticket for $95 per person are available. Travel duration is 23h 10m
|
||
| Greyhound US | 19h 45m | 10:10 PM | Chicago | Downtown Bus Station | 6:55 PM | Knoxville, TN | Greyhound Bus Station | Economy | $103 |
A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 12/8/2025 10:10:00 PM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 12/9/2025 6:55:00 PM. 50 Economy ticket for $103 per person are available. Travel duration is 19h 45m
|
Best Price Offer: The price for the cheapest bus from Chicago to Knoxville, TN is $95 on 12/8/2025. Flexible travelers save on ticket prices.
Frequency of bus connections between Chicago and Knoxville, TN
Monday
is the busiest day, with more than 3 daily buses from Chicago to Knoxville, TN. Monday has instead the fewest connections, with only 3 daily coaches between Chicago and Knoxville, TN.
The busiest time of the day is the Evening, with 4 buses from Chicago to Knoxville, TN, while Morning sees the fewest connections between Chicago and Knoxville, TN, with 2 offers.
Facts about the bus from Chicago to Knoxville, TN
Compare all providers like Greyhound US that travel 3 times every day by bus from Chicago to Knoxville, TN in one click! Book your bus ticket from Chicago to Knoxville, TN starting from $95!
| Cheapest Bus | $95 |
| Fastest Bus | 16h 30m |
| Earliest Bus | 6:10 AM |
| Latest Bus | 10:30 PM |
| Daily Bus Routes | 3 Ø |
| Distance | 455.0 miles |
| Bus Companies | Greyhound US |
Cheapest bus connections from Chicago to Knoxville, TN
Every day, 3 buses from 1 bus companies leave Chicago for Knoxville, TN: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/05/2025 and for the following days.
Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday
11/30
Monday
12/01
Tuesday
12/02
Wednesday
12/03
Thursday
12/04
Friday
12/05
Saturday
12/06
$104
Sunday
12/07
Monday
12/08
$95
Tuesday
12/09
Wednesday
12/10
Thursday
12/11
Friday
12/12
Saturday
12/13
$104
Sunday
12/14
Monday
12/15
$97
Tuesday
12/16
Wednesday
12/17
Thursday
12/18
Friday
12/19
Saturday
12/20
Sunday
12/21
Monday
12/22
Tuesday
12/23
Wednesday
12/24
Thursday
12/25
Friday
12/26
Saturday
12/27
The cheapest time to travel from Chicago to Knoxville, TN
With a price starting from $95, Monday is the cheapest day for a bus from Chicago to Knoxville, TN. Saturday instead is the most expensive day with prices starting from $104.
Morning
is the cheapest day time for bus tickets from Chicago to Knoxville, TN, with $95. Evening is the most expensive time of the day with prices starting from $95.
How to save money travelling from Chicago to Knoxville, TN
Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:
Book the ticket from Chicago to Knoxville, TN in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Chicago to Knoxville, TN, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Chicago to Knoxville, TN are also emptier.Beloved bus companies from Chicago to Knoxville, TN
These are the most booked bus companies between Chicago to Knoxville, TN from our users.
Greyhound US from Chicago to Knoxville, TN
Here you will find the key facts about the Greyhound US bus route Chicago to Knoxville, TN:
| Cheapest Price | $95 |
| Fastest Bus | 16h 30m |
| Earliest Bus | 6:10 AM |
| Last Bus | 10:30 PM |
| Daily Connections | 3 Ø |
| Found on | 11/29/2025 |
All bus stations and stops in Chicago and Knoxville, TN
In the map below, you can see where to find all bus stations in Chicago and Knoxville, TN.
Service and Comfort on the bus from Chicago to Knoxville, TN
Want to know which seat classes are available on the buses from Chicago to Knoxville, TN? Or which bus companies serve the route Chicago to Knoxville, TN? Below you will find answers to your questions.
FAQs about the Chicago to Knoxville, TN bus
How much does a Chicago Knoxville, TN bus trip cost?
This depends on, among other things, the day and time of travel. The cheapest trip is available from $95 and takes 16h 30m to reach Knoxville, TN. Compare offers to save money!
How much could I save by comparing buses from Chicago to Knoxville, TN?
This route is offered by 1 companies with a range of ticket prices between $95 and $114. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Knoxville, TN.
On average, how many connections are available from Chicago to Knoxville, TN each day?
Every day, the Chicago to Knoxville, TN bus route is served by approximately 3 connections. With our search, you can compare bus times to find the perfect trip.
How long does a bus journey from Chicago to Knoxville, TN take?
The fastest bus from Chicago to Knoxville, TN is offered by Greyhound US and takes 16h 30m. Bus tickets for this connection cost $114. In this context, bear in mind that the journey can take longer due to traffic.
What time is the first bus from Chicago to Knoxville, TN?
The earliest bus arriving in Knoxville, TN from Chicago starts at 6:10 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.
What time is the last bus from Chicago to Knoxville, TN?
The latest bus trip departing from Chicago for Knoxville, TN starts at 10:30 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.
Which bus companies operate the Chicago Knoxville, TN route?
When traveling by bus from Chicago to Knoxville, TN, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.
Is there a direct bus between Chicago and Knoxville, TN?
You can check all the direct connections between Chicago and Knoxville, TN by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.
What can I take with me on the Chicago to Knoxville, TN bus route?
Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Chicago Knoxville, TN bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.
What equipment is available for the Chicago Knoxville, TN bus route?
The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Chicago to Knoxville, TN on your planned travel date.
Available seat classes which are offered on the bus route Chicago to Knoxville, TN
Economy
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
More bus routes to Chicago and to Knoxville, TN
Here’s an overview of the most popular bus routes to Chicago and to Knoxville, TN. Simply click on the connection of your choice, and you will find all the details about your bus route!
- Bus Routes to Chicago
- Bus from Bloomington, IN to Chicago
- Bus Cincinnati - Chicago
- Buses Cleveland to Chicago
- Bus Columbus, OH to Chicago
- From Dallas to Chicago bus
- Bus to Chicago from Durango, DG
- Buses from El Paso, TX to Chicago
- Bus Hamilton, ON to Chicago
- Bus Holland, MI - Chicago
- Bus from Houston to Chicago
- Bus Iowa City, IA to Chicago
- Bus to Chicago from Kalamazoo, MI
- Buses to Chicago from Lansing, MI
- Bus from Nuevo Laredo to Chicago
- Bus Omaha - Chicago
- Bus to Chicago from Orlando, FL
- Buses to Chicago from San Antonio, TX
- Bus to Chicago from South Bend, IN
- From Tampa to Chicago bus
- From Toledo, OH to Chicago bus
- Bus Routes to Knoxville, TN
- Bus from Athens, TN to Knoxville, TN
- Bus Austin - Knoxville, TN
- Dallas to Knoxville, TN bus
- Detroit to Knoxville, TN bus
- Bus to Knoxville, TN from Durham, NC
- From Fayetteville, NC to Knoxville, TN bus
- Buses Gainesville, FL - Knoxville, TN
- Bus to Knoxville, TN from Greensboro, NC
- Buses Houston - Knoxville, TN
- Buses to Knoxville, TN from Huntington Park, CA
- Bus Los Angeles - Knoxville, TN
- Buses Miami - Knoxville, TN
- Buses to Knoxville, TN from Midland, TX
- Bus Murfreesboro, TN to Knoxville, TN
- Bus Philadelphia to Knoxville, TN
- Buses to Knoxville, TN from Phoenix, AZ
- Richmond, VA to Knoxville, TN bus
- San Jose, CA to Knoxville, TN bus
- Buses Silver Spring, MD - Knoxville, TN
- Buses St. Louis, MO to Knoxville, TN
Popular Airport Shuttles to Chicago and to Knoxville, TN
