Compare all timetables for the bus from Houston to Knoxville, TN
Here is a selection of the cheapest bus trips from the schedule from Houston to Knoxville, TN from various bus operators like FlixBus, Greyhound US or Greyhound Lines Mexico for the next days.
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 27h 40m | 6:00 PM | Houston | Downtown Houston | 10:40 PM | Knoxville, TN | Knoxville Area Transit Bus Stop | Economy | $139 |
A Bus from FlixBus goes from Downtown Houston, Houston (USA) at 12/5/2025 6:00:00 PM to Knoxville Area Transit Bus Stop, Knoxville, TN (USA) arriving at 12/6/2025 10:40:00 PM. 50 Economy ticket for $139 per person are available. Travel duration is 27h 40m
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| FlixBus | 28h 5m | 5:35 PM | Houston | Uptown/Upper Kirby | 10:40 PM | Knoxville, TN | Knoxville Area Transit Bus Stop | Economy | $141 |
A Bus from FlixBus goes from Uptown/Upper Kirby, Houston (USA) at 12/5/2025 5:35:00 PM to Knoxville Area Transit Bus Stop, Knoxville, TN (USA) arriving at 12/6/2025 10:40:00 PM. 50 Economy ticket for $141 per person are available. Travel duration is 28h 5m
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| Greyhound Lines Mexico | 36h 10m | 9:30 AM | Houston | SW Agencia Autobuses | 10:40 PM | Knoxville, TN | Knoxville Area Transit Bus Stop | Economy | $142 |
A Bus from Greyhound Lines Mexico goes from SW Agencia Autobuses, Houston (USA) at 12/5/2025 9:30:00 AM to Knoxville Area Transit Bus Stop, Knoxville, TN (USA) arriving at 12/6/2025 10:40:00 PM. 50 Economy ticket for $142 per person are available. Travel duration is 36h 10m
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| Greyhound US | 22h 50m | 10:00 PM | Houston | Harrisburg Blvd Station | 9:50 PM | Knoxville, TN | Knoxville Area Transit Bus Stop | Economy | $143 |
A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 12/5/2025 10:00:00 PM to Knoxville Area Transit Bus Stop, Knoxville, TN (USA) arriving at 12/6/2025 9:50:00 PM. 50 Economy ticket for $143 per person are available. Travel duration is 22h 50m
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| Valley Transit | 38h 15m | 6:35 AM | Houston | SW Agencia Autobuses | 9:50 PM | Knoxville, TN | Knoxville Area Transit Bus Stop | Economy | $144 |
A Bus from Valley Transit goes from SW Agencia Autobuses, Houston (USA) at 12/5/2025 6:35:00 AM to Knoxville Area Transit Bus Stop, Knoxville, TN (USA) arriving at 12/6/2025 9:50:00 PM. 50 Economy ticket for $144 per person are available. Travel duration is 38h 15m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 22h 50m | 10:00 PM | Houston | Harrisburg Blvd Station | 9:50 PM | Knoxville, TN | Greyhound Bus Station | Economy | $143 |
A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 12/6/2025 10:00:00 PM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 12/7/2025 9:50:00 PM. 50 Economy ticket for $143 per person are available. Travel duration is 22h 50m
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| FlixBus | 38h 15m | 6:35 AM | Houston | SW Agencia Autobuses | 9:50 PM | Knoxville, TN | Greyhound Bus Station | Economy | $144 |
A Bus from FlixBus goes from SW Agencia Autobuses, Houston (USA) at 12/6/2025 6:35:00 AM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 12/7/2025 9:50:00 PM. 50 Economy ticket for $144 per person are available. Travel duration is 38h 15m
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| FlixBus | 31h 0m | 1:50 PM | Houston | Uptown/Upper Kirby | 9:50 PM | Knoxville, TN | Greyhound Bus Station | Economy | $144 |
A Bus from FlixBus goes from Uptown/Upper Kirby, Houston (USA) at 12/6/2025 1:50:00 PM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 12/7/2025 9:50:00 PM. 50 Economy ticket for $144 per person are available. Travel duration is 31h 0m
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| Greyhound Lines Mexico | 36h 10m | 9:30 AM | Houston | SW Agencia Autobuses | 10:40 PM | Knoxville, TN | Greyhound Bus Station | Economy | $144 |
A Bus from Greyhound Lines Mexico goes from SW Agencia Autobuses, Houston (USA) at 12/6/2025 9:30:00 AM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 12/7/2025 10:40:00 PM. 50 Economy ticket for $144 per person are available. Travel duration is 36h 10m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 22h 50m | 10:00 PM | Houston | Harrisburg Blvd Station | 9:50 PM | Knoxville, TN | Knoxville Area Transit Bus Stop | Economy | $119 |
A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 12/8/2025 10:00:00 PM to Knoxville Area Transit Bus Stop, Knoxville, TN (USA) arriving at 12/9/2025 9:50:00 PM. 50 Economy ticket for $119 per person are available. Travel duration is 22h 50m
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| FlixBus | 31h 35m | 1:15 PM | Houston | Uptown/Upper Kirby | 9:50 PM | Knoxville, TN | Knoxville Area Transit Bus Stop | Economy | $121 |
A Bus from FlixBus goes from Uptown/Upper Kirby, Houston (USA) at 12/8/2025 1:15:00 PM to Knoxville Area Transit Bus Stop, Knoxville, TN (USA) arriving at 12/9/2025 9:50:00 PM. 50 Economy ticket for $121 per person are available. Travel duration is 31h 35m
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| FlixBus | 28h 5m | 5:35 PM | Houston | Uptown/Upper Kirby | 10:40 PM | Knoxville, TN | Knoxville Area Transit Bus Stop | Economy | $121 |
A Bus from FlixBus goes from Uptown/Upper Kirby, Houston (USA) at 12/8/2025 5:35:00 PM to Knoxville Area Transit Bus Stop, Knoxville, TN (USA) arriving at 12/9/2025 10:40:00 PM. 50 Economy ticket for $121 per person are available. Travel duration is 28h 5m
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| Valley Transit | 38h 15m | 6:35 AM | Houston | SW Agencia Autobuses | 9:50 PM | Knoxville, TN | Knoxville Area Transit Bus Stop | Economy | $123 |
A Bus from Valley Transit goes from SW Agencia Autobuses, Houston (USA) at 12/8/2025 6:35:00 AM to Knoxville Area Transit Bus Stop, Knoxville, TN (USA) arriving at 12/9/2025 9:50:00 PM. 50 Economy ticket for $123 per person are available. Travel duration is 38h 15m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 27h 45m | 5:05 PM | Houston | Downtown Houston | 9:50 PM | Knoxville, TN | Greyhound Bus Station | Economy | $125 |
A Bus from FlixBus goes from Downtown Houston, Houston (USA) at 12/11/2025 5:05:00 PM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 12/12/2025 9:50:00 PM. 50 Economy ticket for $125 per person are available. Travel duration is 27h 45m
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| Greyhound Lines Mexico | 36h 10m | 9:30 AM | Houston | SW Agencia Autobuses | 10:40 PM | Knoxville, TN | Greyhound Bus Station | Economy | $126 |
A Bus from Greyhound Lines Mexico goes from SW Agencia Autobuses, Houston (USA) at 12/11/2025 9:30:00 AM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 12/12/2025 10:40:00 PM. 50 Economy ticket for $126 per person are available. Travel duration is 36h 10m
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| FlixBus | 31h 0m | 1:50 PM | Houston | Uptown/Upper Kirby | 9:50 PM | Knoxville, TN | Greyhound Bus Station | Economy | $126 |
A Bus from FlixBus goes from Uptown/Upper Kirby, Houston (USA) at 12/11/2025 1:50:00 PM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 12/12/2025 9:50:00 PM. 50 Economy ticket for $126 per person are available. Travel duration is 31h 0m
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| Valley Transit | 38h 15m | 6:35 AM | Houston | SW Agencia Autobuses | 9:50 PM | Knoxville, TN | Knoxville Area Transit Bus Stop | Economy | $127 |
A Bus from Valley Transit goes from SW Agencia Autobuses, Houston (USA) at 12/11/2025 6:35:00 AM to Knoxville Area Transit Bus Stop, Knoxville, TN (USA) arriving at 12/12/2025 9:50:00 PM. 50 Economy ticket for $127 per person are available. Travel duration is 38h 15m
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| Greyhound US | 22h 50m | 10:00 PM | Houston | Harrisburg Blvd Station | 9:50 PM | Knoxville, TN | Greyhound Bus Station | Economy | $129 |
A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 12/11/2025 10:00:00 PM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 12/12/2025 9:50:00 PM. 50 Economy ticket for $129 per person are available. Travel duration is 22h 50m
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Best Price Offer: The price for the cheapest bus from Houston to Knoxville, TN is $119 on 12/8/2025. Flexible travelers save on ticket prices.
Frequency of bus connections between Houston and Knoxville, TN
Friday
is the busiest day, with more than 13 daily buses from Houston to Knoxville, TN. Saturday has instead the fewest connections, with only 7 daily coaches between Houston and Knoxville, TN.
The busiest time of the day is the Afternoon, with 21 buses from Houston to Knoxville, TN, while Morning sees the fewest connections between Houston and Knoxville, TN, with 10 offers.
Facts about the bus from Houston to Knoxville, TN
Compare all providers like FlixBus, Greyhound US and Greyhound Lines Mexico that travel 10 times every day by bus from Houston to Knoxville, TN in one click! Book your bus ticket from Houston to Knoxville, TN starting from $119!
| Cheapest Bus | $119 |
| Fastest Bus | 23h 50m |
| Earliest Bus | 6:35 AM |
| Latest Bus | 10:00 PM |
| Daily Bus Routes | 10 Ø |
| Distance | 791.0 miles |
| Bus Companies | FlixBus, Greyhound US, Greyhound Lines Mexico and Valley Transit |
Cheapest bus connections from Houston to Knoxville, TN
Every day, 10 buses from 4 bus companies leave Houston for Knoxville, TN: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/05/2025 and for the following days.
Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday
11/30
Monday
12/01
Tuesday
12/02
Wednesday
12/03
Thursday
12/04
Friday
12/05
$139
Saturday
12/06
$143
Sunday
12/07
Monday
12/08
$125
Tuesday
12/09
Wednesday
12/10
Thursday
12/11
$126
Friday
12/12
$130
Saturday
12/13
Sunday
12/14
Monday
12/15
$133
Tuesday
12/16
Wednesday
12/17
Thursday
12/18
Friday
12/19
$170
Saturday
12/20
Sunday
12/21
Monday
12/22
Tuesday
12/23
Wednesday
12/24
Thursday
12/25
Friday
12/26
Saturday
12/27
The cheapest time to travel from Houston to Knoxville, TN
With a price starting from $119, Monday is the cheapest day for a bus from Houston to Knoxville, TN. Saturday instead is the most expensive day with prices starting from $143.
Evening
is the cheapest day time for bus tickets from Houston to Knoxville, TN, with $119. Morning is the most expensive time of the day with prices starting from $123.
How to save money travelling from Houston to Knoxville, TN
Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:
Book the ticket from Houston to Knoxville, TN in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Houston to Knoxville, TN, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Houston to Knoxville, TN are also emptier.Beloved bus companies from Houston to Knoxville, TN
These are the most booked bus companies between Houston to Knoxville, TN from our users.
Greyhound US from Houston to Knoxville, TN
Here you will find the key facts about the Greyhound US bus route Houston to Knoxville, TN:
| Cheapest Price | $119 |
| Fastest Bus | 23h 50m |
| Earliest Bus | 10:00 PM |
| Last Bus | 10:00 PM |
| Daily Connections | 1 Ø |
| Found on | 12/1/2025 |
All bus stations and stops in Houston and Knoxville, TN
In the map below, you can see where to find all bus stations in Houston and Knoxville, TN.
Service and Comfort on the bus from Houston to Knoxville, TN
Want to know which seat classes are available on the buses from Houston to Knoxville, TN? Or which bus companies serve the route Houston to Knoxville, TN? Below you will find answers to your questions.
FAQs about the Houston to Knoxville, TN bus
How much does a Houston Knoxville, TN bus trip cost?
This depends on, among other things, the day and time of travel. The cheapest trip is available from $119 and takes 23h 50m to reach Knoxville, TN. Compare offers to save money!
How much could I save by comparing buses from Houston to Knoxville, TN?
This route is offered by 4 companies with a range of ticket prices between $119 and $146. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Knoxville, TN.
On average, how many connections are available from Houston to Knoxville, TN each day?
Every day, the Houston to Knoxville, TN bus route is served by approximately 10 connections. With our search, you can compare bus times to find the perfect trip.
How long does a bus journey from Houston to Knoxville, TN take?
The fastest bus from Houston to Knoxville, TN is offered by Greyhound US and takes 23h 50m. Bus tickets for this connection cost $146. In this context, bear in mind that the journey can take longer due to traffic.
What time is the first bus from Houston to Knoxville, TN?
The earliest bus arriving in Knoxville, TN from Houston starts at 6:35 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.
What time is the last bus from Houston to Knoxville, TN?
The latest bus trip departing from Houston for Knoxville, TN starts at 10:00 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.
Which bus companies operate the Houston Knoxville, TN route?
When traveling by bus from Houston to Knoxville, TN, passengers can travel with FlixBus, Greyhound US and Greyhound Lines Mexico. With our search, you can compare all available bus tickets to book the one that works for you.
Is there a direct bus between Houston and Knoxville, TN?
You can check all the direct connections between Houston and Knoxville, TN by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus, Greyhound US and Greyhound Lines Mexico.
What can I take with me on the Houston to Knoxville, TN bus route?
Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Houston Knoxville, TN bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.
What equipment is available for the Houston Knoxville, TN bus route?
The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Houston to Knoxville, TN on your planned travel date.
Available seat classes which are offered on the bus route Houston to Knoxville, TN
Economy
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
More bus routes to Houston and to Knoxville, TN
Here’s an overview of the most popular bus routes to Houston and to Knoxville, TN. Simply click on the connection of your choice, and you will find all the details about your bus route!
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Popular Airport Shuttles to Houston and to Knoxville, TN
