Which bus from Houston to Knoxville, TN is the cheapest?

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Compare all timetables for the bus from Houston to Knoxville, TN

Here is a selection of the cheapest bus trips from the schedule from Houston to Knoxville, TN from various bus operators like FlixBus, Greyhound US or Greyhound Lines Mexico for the next days.

today
$171
tomorrow
Sunday
$171
Monday
Tuesday
$156
Wednesday
Thursday

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 22h 50m 10:00 PM Houston Harrisburg Blvd Station 9:50 PM Knoxville, TN Knoxville Area Transit Bus Stop  Economy $171
FlixBus 31h 0m 1:50 PM Houston Uptown/Upper Kirby 9:50 PM Knoxville, TN Knoxville Area Transit Bus Stop  Economy $172
FlixBus 27h 45m 5:05 PM Houston Downtown Houston 9:50 PM Knoxville, TN Knoxville Area Transit Bus Stop  Economy $174
FlixBus 28h 5m 5:35 PM Houston Uptown/Upper Kirby 10:40 PM Knoxville, TN Knoxville Area Transit Bus Stop  Economy $258

Cheapest bus trips Sunday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 22h 50m 10:00 PM Houston Harrisburg Blvd Station 9:50 PM Knoxville, TN Greyhound Bus Station  Economy $171
FlixBus 27h 45m 5:05 PM Houston Downtown Houston 9:50 PM Knoxville, TN Greyhound Bus Station  Economy $177
FlixBus 38h 15m 6:35 AM Houston SW Agencia Autobuses 9:50 PM Knoxville, TN Greyhound Bus Station  Economy $178
Greyhound Lines Mexico 36h 10m 9:30 AM Houston SW Agencia Autobuses 10:40 PM Knoxville, TN Greyhound Bus Station  Economy $263
  • Did you know that if you travel from Houston to Knoxville, TN via Atlanta, GA, you can save more than $37? You can find the corresponding connections below.
    • Busbud
      31h 45m
      0
      1:05 PM
      Houston
      Harrisburg Blvd Station
      7:25 AM
      Atlanta, GA
      Garnett Transit Station
      0
      Busbud
      Economy
      $87
      • Waiting Time 10h 40m
    • FlixBus
      3h 45m
      0
      6:05 PM
      Atlanta, GA
      Garnett Transit Station
      9:50 PM
      Knoxville, TN
      Greyhound Bus Station
      0
      FlixBus
      Economy
      $47
    Travel time is 7h 55m longer, but you will save $37

Cheapest bus trips Tuesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 22h 50m 10:00 PM Houston Harrisburg Blvd Station 9:50 PM Knoxville, TN Greyhound Bus Station  Economy $156
FlixBus 38h 15m 6:35 AM Houston SW Agencia Autobuses 9:50 PM Knoxville, TN Greyhound Bus Station  Economy $175
FlixBus 33h 40m 11:10 AM Houston Downtown Houston 9:50 PM Knoxville, TN Greyhound Bus Station  Economy $187
FlixBus 33h 25m 11:25 AM Houston Uptown/Upper Kirby 9:50 PM Knoxville, TN Greyhound Bus Station  Economy $187
  • Did you know that if you travel from Houston to Knoxville, TN via Atlanta, GA, you can save more than $22? You can find the corresponding connections below.
    • Busbud
      31h 45m
      0
      1:05 PM
      Houston
      Harrisburg Blvd Station
      7:25 AM
      Atlanta, GA
      Garnett Transit Station
      0
      Busbud
      Economy
      $87
      • Waiting Time 10h 40m
    • FlixBus
      3h 45m
      0
      6:05 PM
      Atlanta, GA
      Garnett Transit Station
      9:50 PM
      Knoxville, TN
      Greyhound Bus Station
      0
      FlixBus
      Economy
      $47
    Travel time is 7h 55m longer, but you will save $22

Best Price Offer: The price for the cheapest bus from Houston to Knoxville, TN is $137 on 12/15/2025. Flexible travelers save on ticket prices.


Frequency of bus connections between Houston and Knoxville, TN

See here how frequent the connections between Houston and Knoxville, TN are, during different times and days of the week.
Friday is the busiest day, with more than 9 daily buses from Houston to Knoxville, TN. Tuesday has instead the fewest connections, with only 4 daily coaches between Houston and Knoxville, TN.
The busiest time of the day is the Afternoon, with 9 buses from Houston to Knoxville, TN, while Morning sees the fewest connections between Houston and Knoxville, TN, with 5 offers.

Facts about the bus from Houston to Knoxville, TN

Compare all providers like FlixBus, Greyhound US and Greyhound Lines Mexico that travel 6 times every day by bus from Houston to Knoxville, TN in one click! Book your bus ticket from Houston to Knoxville, TN starting from $137!

Cheapest Bus $137
Fastest Bus 23h 50m
Earliest Bus 1:50 PM
Latest Bus 10:00 PM
Daily Bus Routes 6 Ø
Distance 791.0 miles
Bus Companies FlixBus, Greyhound US and Greyhound Lines Mexico

Cheapest bus connections from Houston to Knoxville, TN

Every day, 6 buses from 3 bus companies leave Houston for Knoxville, TN: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/19/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 12/14
Monday 12/15
Tuesday 12/16
Wednesday 12/17
Thursday 12/18
Friday 12/19
$178
Saturday 12/20
Sunday 12/21
$171
Monday 12/22
Tuesday 12/23
$156
Wednesday 12/24
Thursday 12/25
Friday 12/26
Saturday 12/27
Sunday 12/28
Monday 12/29
Tuesday 12/30
Wednesday 12/31
Thursday 01/01
Friday 01/02
Saturday 01/03
Sunday 01/04
$154
Monday 01/05
Tuesday 01/06
Wednesday 01/07
Thursday 01/08
Friday 01/09
Saturday 01/10

The cheapest time to travel from Houston to Knoxville, TN

See here on which day and which time of the day you can find the cheapest bus ticket from Houston to Knoxville, TN, for the next 30 days.
With a price starting from $154, Sunday is the cheapest day for a bus from Houston to Knoxville, TN. Friday instead is the most expensive day with prices starting from $171.
Evening is the cheapest day time for bus tickets from Houston to Knoxville, TN, with $156. Morning is the most expensive time of the day with prices starting from $175.

How to save money travelling from Houston to Knoxville, TN

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Houston to Knoxville, TN in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Houston to Knoxville, TN, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Houston to Knoxville, TN are also emptier.

Beloved bus companies from Houston to Knoxville, TN

These are the most booked bus companies between Houston to Knoxville, TN from our users.

Greyhound US from Houston to Knoxville, TN

Greyhound US

Here you will find the key facts about the Greyhound US bus route Houston to Knoxville, TN:

Cheapest Price $156
Fastest Bus 23h 50m
Earliest Bus 10:00 PM
Last Bus 10:00 PM
Daily Connections 1 Ø
Found on 12/14/2025

All bus stations and stops in Houston and Knoxville, TN

In the map below, you can see where to find all bus stations in Houston and Knoxville, TN.

Service and Comfort on the bus from Houston to Knoxville, TN

Want to know which seat classes are available on the buses from Houston to Knoxville, TN? Or which bus companies serve the route Houston to Knoxville, TN? Below you will find answers to your questions.

FAQs about the Houston to Knoxville, TN bus

How much does a Houston Knoxville, TN bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $137 and takes 23h 50m to reach Knoxville, TN. Compare offers to save money!

How much could I save by comparing buses from Houston to Knoxville, TN?

This route is offered by 3 companies with a range of ticket prices between $137 and $278. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Knoxville, TN.

On average, how many connections are available from Houston to Knoxville, TN each day?

Every day, the Houston to Knoxville, TN bus route is served by approximately 6 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Houston to Knoxville, TN take?

The fastest bus from Houston to Knoxville, TN is offered by Greyhound US and takes 23h 50m. Bus tickets for this connection cost $171. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Houston to Knoxville, TN?

The earliest bus arriving in Knoxville, TN from Houston starts at 1:50 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Houston to Knoxville, TN?

The latest bus trip departing from Houston for Knoxville, TN starts at 10:00 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Houston Knoxville, TN route?

When traveling by bus from Houston to Knoxville, TN, passengers can travel with FlixBus, Greyhound US and Greyhound Lines Mexico. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Houston and Knoxville, TN?

You can check all the direct connections between Houston and Knoxville, TN by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus, Greyhound US and Greyhound Lines Mexico.

What can I take with me on the Houston to Knoxville, TN bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Houston Knoxville, TN bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Houston Knoxville, TN bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Houston to Knoxville, TN on your planned travel date.

How does CheckMyBus find the best bus deals from Houston to Knoxville, TN?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 6 daily trips between Houston and Knoxville, TN. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Houston to Knoxville, TN?

Prices and availability for 6 trips between Houston and Knoxville, TN change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Houston to Knoxville, TN

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Houston and to Knoxville, TN

Here’s an overview of the most popular bus routes to Houston and to Knoxville, TN. Simply click on the connection of your choice, and you will find all the details about your bus route!
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From Corpus Christi to Houston bus From Corpus Christi to Houston bus
Buses Indianapolis - Knoxville, TN Buses Indianapolis - Knoxville, TN
Bus Cincinnati - Knoxville, TN Bus Cincinnati - Knoxville, TN
Buses Tampa - Knoxville, TN Buses Tampa - Knoxville, TN
Bus Orlando, FL to Knoxville, TN Bus Orlando, FL to Knoxville, TN
Popular Airport Shuttles to Houston and to Knoxville, TN
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