Bus Phoenix, AZ to Knoxville, TN: Compare prices and save money

Compare all timetables for the bus from Phoenix, AZ to Knoxville, TN

Here is a selection of the cheapest bus trips from the schedule from Phoenix, AZ to Knoxville, TN from various bus operators like Greyhound US or FlixBus for the next days.

today

$154

tomorrow

$183

Wednesday

$188

Thursday

$182

Friday

$178

Saturday

$174

Sunday

$151

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	44h 5m	10:45 PM	Phoenix, AZ	Bus Station	9:50 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	Economy	$154	A Bus from Greyhound US goes from Bus Station, Phoenix, AZ (USA) at 4/20/2026 10:45:00 PM to Knoxville Area Transit Bus Stop, Knoxville, TN (USA) arriving at 4/22/2026 9:50:00 PM. 50 Economy ticket for $154 per person are available. Travel duration is 44h 5m
Greyhound US	39h 30m	4:10 AM	Phoenix, AZ	Bus Station	10:40 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	Economy	$155	A Bus from Greyhound US goes from Bus Station, Phoenix, AZ (USA) at 4/20/2026 4:10:00 AM to Knoxville Area Transit Bus Stop, Knoxville, TN (USA) arriving at 4/21/2026 10:40:00 PM. 50 Economy ticket for $155 per person are available. Travel duration is 39h 30m
Greyhound US	54h 55m	9:35 AM	Phoenix, AZ	Bus Station	7:30 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	Economy	$167	A Bus from Greyhound US goes from Bus Station, Phoenix, AZ (USA) at 4/20/2026 9:35:00 AM to Knoxville Area Transit Bus Stop, Knoxville, TN (USA) arriving at 4/22/2026 7:30:00 PM. 50 Economy ticket for $167 per person are available. Travel duration is 54h 55m
Greyhound US	57h 10m	7:20 AM	Phoenix, AZ	44th St/Washington	7:30 PM	Knoxville, TN	Greyhound Bus Station	Economy	$172	A Bus from Greyhound US goes from 44th St/Washington, Phoenix, AZ (USA) at 4/20/2026 7:20:00 AM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 4/22/2026 7:30:00 PM. 50 Economy ticket for $172 per person are available. Travel duration is 57h 10m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	54h 55m	9:35 AM	Phoenix, AZ	Bus Station	7:30 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	Economy	$183	A Bus from Greyhound US goes from Bus Station, Phoenix, AZ (USA) at 4/21/2026 9:35:00 AM to Knoxville Area Transit Bus Stop, Knoxville, TN (USA) arriving at 4/23/2026 7:30:00 PM. 50 Economy ticket for $183 per person are available. Travel duration is 54h 55m
Greyhound US	44h 5m	10:45 PM	Phoenix, AZ	Bus Station	9:50 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	Economy	$183	A Bus from Greyhound US goes from Bus Station, Phoenix, AZ (USA) at 4/21/2026 10:45:00 PM to Knoxville Area Transit Bus Stop, Knoxville, TN (USA) arriving at 4/23/2026 9:50:00 PM. 50 Economy ticket for $183 per person are available. Travel duration is 44h 5m
Greyhound US	39h 30m	4:10 AM	Phoenix, AZ	Bus Station	10:40 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	Economy	$185	A Bus from Greyhound US goes from Bus Station, Phoenix, AZ (USA) at 4/21/2026 4:10:00 AM to Knoxville Area Transit Bus Stop, Knoxville, TN (USA) arriving at 4/22/2026 10:40:00 PM. 50 Economy ticket for $185 per person are available. Travel duration is 39h 30m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	44h 5m	10:45 PM	Phoenix, AZ	Bus Station	9:50 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	Economy	$188	A Bus from Greyhound US goes from Bus Station, Phoenix, AZ (USA) at 4/22/2026 10:45:00 PM to Knoxville Area Transit Bus Stop, Knoxville, TN (USA) arriving at 4/24/2026 9:50:00 PM. 50 Economy ticket for $188 per person are available. Travel duration is 44h 5m
Greyhound US	54h 55m	9:35 AM	Phoenix, AZ	Bus Station	7:30 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	Economy	$189	A Bus from Greyhound US goes from Bus Station, Phoenix, AZ (USA) at 4/22/2026 9:35:00 AM to Knoxville Area Transit Bus Stop, Knoxville, TN (USA) arriving at 4/24/2026 7:30:00 PM. 50 Economy ticket for $189 per person are available. Travel duration is 54h 55m
Greyhound US	39h 30m	4:10 AM	Phoenix, AZ	Bus Station	10:40 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	Economy	$190	A Bus from Greyhound US goes from Bus Station, Phoenix, AZ (USA) at 4/22/2026 4:10:00 AM to Knoxville Area Transit Bus Stop, Knoxville, TN (USA) arriving at 4/23/2026 10:40:00 PM. 50 Economy ticket for $190 per person are available. Travel duration is 39h 30m
Greyhound US	57h 10m	7:20 AM	Phoenix, AZ	44th St/Washington	7:30 PM	Knoxville, TN	Greyhound Bus Station	Economy	$207	A Bus from Greyhound US goes from 44th St/Washington, Phoenix, AZ (USA) at 4/22/2026 7:20:00 AM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 4/24/2026 7:30:00 PM. 50 Economy ticket for $207 per person are available. Travel duration is 57h 10m

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	39h 30m	4:10 AM	Phoenix, AZ	Bus Station	10:40 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	Economy	$182	A Bus from Greyhound US goes from Bus Station, Phoenix, AZ (USA) at 4/23/2026 4:10:00 AM to Knoxville Area Transit Bus Stop, Knoxville, TN (USA) arriving at 4/24/2026 10:40:00 PM. 50 Economy ticket for $182 per person are available. Travel duration is 39h 30m
Greyhound US	44h 5m	10:45 PM	Phoenix, AZ	Bus Station	9:50 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	Economy	$182	A Bus from Greyhound US goes from Bus Station, Phoenix, AZ (USA) at 4/23/2026 10:45:00 PM to Knoxville Area Transit Bus Stop, Knoxville, TN (USA) arriving at 4/25/2026 9:50:00 PM. 50 Economy ticket for $182 per person are available. Travel duration is 44h 5m
Greyhound US	54h 55m	9:35 AM	Phoenix, AZ	Bus Station	7:30 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	Economy	$183	A Bus from Greyhound US goes from Bus Station, Phoenix, AZ (USA) at 4/23/2026 9:35:00 AM to Knoxville Area Transit Bus Stop, Knoxville, TN (USA) arriving at 4/25/2026 7:30:00 PM. 50 Economy ticket for $183 per person are available. Travel duration is 54h 55m
Greyhound US	57h 10m	7:20 AM	Phoenix, AZ	44th St/Washington	7:30 PM	Knoxville, TN	Greyhound Bus Station	Economy	$187	A Bus from Greyhound US goes from 44th St/Washington, Phoenix, AZ (USA) at 4/23/2026 7:20:00 AM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 4/25/2026 7:30:00 PM. 50 Economy ticket for $187 per person are available. Travel duration is 57h 10m

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	39h 30m	4:10 AM	Phoenix, AZ	Bus Station	10:40 PM	Knoxville, TN	Greyhound Bus Station	Economy	$178	A Bus from Greyhound US goes from Bus Station, Phoenix, AZ (USA) at 4/24/2026 4:10:00 AM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 4/25/2026 10:40:00 PM. 50 Economy ticket for $178 per person are available. Travel duration is 39h 30m
Greyhound US	54h 55m	9:35 AM	Phoenix, AZ	Bus Station	7:30 PM	Knoxville, TN	Greyhound Bus Station	Economy	$178	A Bus from Greyhound US goes from Bus Station, Phoenix, AZ (USA) at 4/24/2026 9:35:00 AM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 4/26/2026 7:30:00 PM. 50 Economy ticket for $178 per person are available. Travel duration is 54h 55m
FlixBus	75h 50m	12:40 PM	Phoenix, AZ	44th St/Washington	7:30 PM	Knoxville, TN	Greyhound Bus Station	Economy	$178	A Bus from FlixBus goes from 44th St/Washington, Phoenix, AZ (USA) at 4/24/2026 12:40:00 PM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 4/27/2026 7:30:00 PM. 50 Economy ticket for $178 per person are available. Travel duration is 75h 50m
Greyhound US	57h 10m	7:20 AM	Phoenix, AZ	44th St/Washington	7:30 PM	Knoxville, TN	Greyhound Bus Station	Economy	$179	A Bus from Greyhound US goes from 44th St/Washington, Phoenix, AZ (USA) at 4/24/2026 7:20:00 AM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 4/26/2026 7:30:00 PM. 50 Economy ticket for $179 per person are available. Travel duration is 57h 10m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	54h 55m	9:35 AM	Phoenix, AZ	Bus Station	7:30 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	Economy	$174	A Bus from Greyhound US goes from Bus Station, Phoenix, AZ (USA) at 4/25/2026 9:35:00 AM to Knoxville Area Transit Bus Stop, Knoxville, TN (USA) arriving at 4/27/2026 7:30:00 PM. 50 Economy ticket for $174 per person are available. Travel duration is 54h 55m
Greyhound US	39h 30m	4:10 AM	Phoenix, AZ	Bus Station	10:40 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	Economy	$176	A Bus from Greyhound US goes from Bus Station, Phoenix, AZ (USA) at 4/25/2026 4:10:00 AM to Knoxville Area Transit Bus Stop, Knoxville, TN (USA) arriving at 4/26/2026 10:40:00 PM. 50 Economy ticket for $176 per person are available. Travel duration is 39h 30m
Greyhound US	44h 5m	10:45 PM	Phoenix, AZ	Bus Station	9:50 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	Economy	$176	A Bus from Greyhound US goes from Bus Station, Phoenix, AZ (USA) at 4/25/2026 10:45:00 PM to Knoxville Area Transit Bus Stop, Knoxville, TN (USA) arriving at 4/27/2026 9:50:00 PM. 50 Economy ticket for $176 per person are available. Travel duration is 44h 5m
Greyhound US	57h 10m	7:20 AM	Phoenix, AZ	44th St/Washington	7:30 PM	Knoxville, TN	Greyhound Bus Station	Economy	$179	A Bus from Greyhound US goes from 44th St/Washington, Phoenix, AZ (USA) at 4/25/2026 7:20:00 AM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 4/27/2026 7:30:00 PM. 50 Economy ticket for $179 per person are available. Travel duration is 57h 10m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	39h 30m	4:10 AM	Phoenix, AZ	Bus Station	10:40 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	Economy	$151	A Bus from Greyhound US goes from Bus Station, Phoenix, AZ (USA) at 4/26/2026 4:10:00 AM to Knoxville Area Transit Bus Stop, Knoxville, TN (USA) arriving at 4/27/2026 10:40:00 PM. 50 Economy ticket for $151 per person are available. Travel duration is 39h 30m
Greyhound US	54h 55m	9:35 AM	Phoenix, AZ	Bus Station	7:30 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	Economy	$153	A Bus from Greyhound US goes from Bus Station, Phoenix, AZ (USA) at 4/26/2026 9:35:00 AM to Knoxville Area Transit Bus Stop, Knoxville, TN (USA) arriving at 4/28/2026 7:30:00 PM. 50 Economy ticket for $153 per person are available. Travel duration is 54h 55m
Greyhound US	44h 5m	10:45 PM	Phoenix, AZ	Bus Station	9:50 PM	Knoxville, TN	Knoxville Area Transit Bus Stop	Economy	$153	A Bus from Greyhound US goes from Bus Station, Phoenix, AZ (USA) at 4/26/2026 10:45:00 PM to Knoxville Area Transit Bus Stop, Knoxville, TN (USA) arriving at 4/28/2026 9:50:00 PM. 50 Economy ticket for $153 per person are available. Travel duration is 44h 5m
FlixBus	75h 50m	12:40 PM	Phoenix, AZ	44th St/Washington	7:30 PM	Knoxville, TN	Greyhound Bus Station	Economy	$158	A Bus from FlixBus goes from 44th St/Washington, Phoenix, AZ (USA) at 4/26/2026 12:40:00 PM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 4/29/2026 7:30:00 PM. 50 Economy ticket for $158 per person are available. Travel duration is 75h 50m

Best Price Offer: The price for the cheapest bus from Phoenix, AZ to Knoxville, TN is $135 on 4/19/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Phoenix, AZ and Knoxville, TN

See here how frequent the connections between Phoenix, AZ and Knoxville, TN are, during different times and days of the week.

Sunday is the busiest day, with more than 8 daily buses from Phoenix, AZ to Knoxville, TN. Tuesday has instead the fewest connections, with only 3 daily coaches between Phoenix, AZ and Knoxville, TN.

The busiest time of the day is the Morning, with 18 buses from Phoenix, AZ to Knoxville, TN, while Afternoon sees the fewest connections between Phoenix, AZ and Knoxville, TN, with 2 offers.

Facts about the bus from Phoenix, AZ to Knoxville, TN

Compare all providers like Greyhound US and FlixBus that travel 6 times every day by bus from Phoenix, AZ to Knoxville, TN in one click! Book your bus ticket from Phoenix, AZ to Knoxville, TN starting from $135!

Cheapest Bus	$135
Fastest Bus	42h 30m
Earliest Bus	4:10 AM
Latest Bus	10:45 PM
Daily Bus Routes	6 Ø
Distance	1,603.9 miles
Bus Companies	Greyhound US and FlixBus

Cheapest bus connections from Phoenix, AZ to Knoxville, TN

Every day, 6 buses from 2 bus companies leave Phoenix, AZ for Knoxville, TN: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 04/20/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 04/19

Monday 04/20

$154

Tuesday 04/21

$183

Wednesday 04/22

$204

Thursday 04/23

$187

Friday 04/24

$178

Saturday 04/25

$178

Sunday 04/26

$151

Monday 04/27

$139

Tuesday 04/28

$153

Wednesday 04/29

$162

Thursday 04/30

$174

Friday 05/01

$154

Saturday 05/02

$166

Sunday 05/03

$156

Monday 05/04

$142

Tuesday 05/05

Wednesday 05/06

Thursday 05/07

Friday 05/08

$158

Saturday 05/09

$176

Sunday 05/10

$156

Monday 05/11

$162

Tuesday 05/12

$174

Wednesday 05/13

$177

Thursday 05/14

$152

Friday 05/15

$145

Saturday 05/16

The cheapest time to travel from Phoenix, AZ to Knoxville, TN

See here on which day and which time of the day you can find the cheapest bus ticket from Phoenix, AZ to Knoxville, TN, for the next 30 days.

With a price starting from $139, Monday is the cheapest day for a bus from Phoenix, AZ to Knoxville, TN. Wednesday instead is the most expensive day with prices starting from $162.

Night is the cheapest day time for bus tickets from Phoenix, AZ to Knoxville, TN, with $139. Afternoon is the most expensive time of the day with prices starting from $158.

How to save money travelling from Phoenix, AZ to Knoxville, TN

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Phoenix, AZ to Knoxville, TN in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Phoenix, AZ to Knoxville, TN, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Phoenix, AZ to Knoxville, TN are also emptier.

All bus stations and stops in Phoenix, AZ and Knoxville, TN

In the map below, you can see where to find all bus stations in Phoenix, AZ and Knoxville, TN.

24th St & Jefferson St Station

24th St & Jefferson St

27th Av & McDowell Rd Bus Stop

N 27th Ave 1614

Bus Station

E Buckeye Rd 2115

44th St/Washington

Downtown

S 1st St 401S

Kingston Pike

Kingston Pike 6927

Walker Springs Plaza Shopping Center

Kingston Pike 8509

Greyhound Bus Station

E Magnolia Ave 100

Knoxville Area Transit Bus Stop

Knoxville Area Transit Bus Stop Knoxville Area Transit Bus Stop

Transit Center

E Church Ave 301

Service and Comfort on the bus from Phoenix, AZ to Knoxville, TN

Want to know which seat classes are available on the buses from Phoenix, AZ to Knoxville, TN? Or which bus companies serve the route Phoenix, AZ to Knoxville, TN? Below you will find answers to your questions.

FAQs about the Phoenix, AZ to Knoxville, TN bus

How much does a Phoenix, AZ Knoxville, TN bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $135 and takes 42h 30m to reach Knoxville, TN. Compare offers to save money!

How much could I save by comparing buses from Phoenix, AZ to Knoxville, TN?

This route is offered by 2 companies with a range of ticket prices between $135 and $207. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Knoxville, TN.

On average, how many connections are available from Phoenix, AZ to Knoxville, TN each day?

Every day, the Phoenix, AZ to Knoxville, TN bus route is served by approximately 6 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Phoenix, AZ to Knoxville, TN take?

The fastest bus from Phoenix, AZ to Knoxville, TN is offered by Greyhound US and takes 42h 30m. Bus tickets for this connection cost $159. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Phoenix, AZ to Knoxville, TN?

The earliest bus arriving in Knoxville, TN from Phoenix, AZ starts at 4:10 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Phoenix, AZ to Knoxville, TN?

The latest bus trip departing from Phoenix, AZ for Knoxville, TN starts at 10:45 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Phoenix, AZ Knoxville, TN route?

When traveling by bus from Phoenix, AZ to Knoxville, TN, passengers can travel with Greyhound US and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Phoenix, AZ and Knoxville, TN?

You can check all the direct connections between Phoenix, AZ and Knoxville, TN by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US and FlixBus.

What can I take with me on the Phoenix, AZ to Knoxville, TN bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Phoenix, AZ Knoxville, TN bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Phoenix, AZ Knoxville, TN bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Phoenix, AZ to Knoxville, TN on your planned travel date.

How does CheckMyBus find the best bus deals from Phoenix, AZ to Knoxville, TN?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 6 daily trips between Phoenix, AZ and Knoxville, TN. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Phoenix, AZ to Knoxville, TN?

Prices and availability for 6 trips between Phoenix, AZ and Knoxville, TN change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Phoenix, AZ to Knoxville, TN

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Phoenix, AZ and to Knoxville, TN

Here’s an overview of the most popular bus routes to Phoenix, AZ and to Knoxville, TN. Simply click on the connection of your choice, and you will find all the details about your bus route!