Compare all timetables for the bus from Gainesville, FL to Knoxville, TN
Here is a selection of the cheapest bus trips from the schedule from Gainesville, FL to Knoxville, TN from various bus operators like FlixBus or Greyhound US for the next days.
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 23h 10m | 10:40 PM | Gainesville, FL | Rosa Parks Transfer station | 9:50 PM | Knoxville, TN | Greyhound Bus Station | Economy | $128 |
A Bus from FlixBus goes from Rosa Parks Transfer station, Gainesville, FL (USA) at 12/5/2025 10:40:00 PM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 12/6/2025 9:50:00 PM. 50 Economy ticket for $128 per person are available. Travel duration is 23h 10m
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| FlixBus | 21h 30m | 1:10 AM | Gainesville, FL | Rosa Parks Transfer station | 10:40 PM | Knoxville, TN | Greyhound Bus Station | Economy | $131 |
A Bus from FlixBus goes from Rosa Parks Transfer station, Gainesville, FL (USA) at 12/5/2025 1:10:00 AM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 12/5/2025 10:40:00 PM. 50 Economy ticket for $131 per person are available. Travel duration is 21h 30m
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| Greyhound US | 13h 50m | 8:00 AM | Gainesville, FL | Greyhound Bus Station | 9:50 PM | Knoxville, TN | Greyhound Bus Station | Economy | $134 |
A Bus from Greyhound US goes from Greyhound Bus Station, Gainesville, FL (USA) at 12/5/2025 8:00:00 AM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 12/5/2025 9:50:00 PM. 50 Economy ticket for $134 per person are available. Travel duration is 13h 50m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 23h 10m | 10:40 PM | Gainesville, FL | Rosa Parks Transfer station | 9:50 PM | Knoxville, TN | Greyhound Bus Station | Economy | $124 |
A Bus from FlixBus goes from Rosa Parks Transfer station, Gainesville, FL (USA) at 12/8/2025 10:40:00 PM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 12/9/2025 9:50:00 PM. 50 Economy ticket for $124 per person are available. Travel duration is 23h 10m
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| FlixBus | 21h 30m | 1:10 AM | Gainesville, FL | Rosa Parks Transfer station | 10:40 PM | Knoxville, TN | Greyhound Bus Station | Economy | $126 |
A Bus from FlixBus goes from Rosa Parks Transfer station, Gainesville, FL (USA) at 12/8/2025 1:10:00 AM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 12/8/2025 10:40:00 PM. 50 Economy ticket for $126 per person are available. Travel duration is 21h 30m
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| Greyhound US | 13h 50m | 8:00 AM | Gainesville, FL | Greyhound Bus Station | 9:50 PM | Knoxville, TN | Greyhound Bus Station | Economy | $127 |
A Bus from Greyhound US goes from Greyhound Bus Station, Gainesville, FL (USA) at 12/8/2025 8:00:00 AM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 12/8/2025 9:50:00 PM. 50 Economy ticket for $127 per person are available. Travel duration is 13h 50m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 21h 30m | 1:10 AM | Gainesville, FL | Rosa Parks Transfer station | 10:40 PM | Knoxville, TN | Greyhound Bus Station | Economy | $96 |
A Bus from FlixBus goes from Rosa Parks Transfer station, Gainesville, FL (USA) at 12/10/2025 1:10:00 AM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 12/10/2025 10:40:00 PM. 50 Economy ticket for $96 per person are available. Travel duration is 21h 30m
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| Greyhound US | 13h 50m | 8:00 AM | Gainesville, FL | Greyhound Bus Station | 9:50 PM | Knoxville, TN | Greyhound Bus Station | Economy | $97 |
A Bus from Greyhound US goes from Greyhound Bus Station, Gainesville, FL (USA) at 12/10/2025 8:00:00 AM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 12/10/2025 9:50:00 PM. 50 Economy ticket for $97 per person are available. Travel duration is 13h 50m
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| FlixBus | 23h 10m | 10:40 PM | Gainesville, FL | Rosa Parks Transfer station | 9:50 PM | Knoxville, TN | Greyhound Bus Station | Economy | $101 |
A Bus from FlixBus goes from Rosa Parks Transfer station, Gainesville, FL (USA) at 12/10/2025 10:40:00 PM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 12/11/2025 9:50:00 PM. 50 Economy ticket for $101 per person are available. Travel duration is 23h 10m
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Best Price Offer: The price for the cheapest bus from Gainesville, FL to Knoxville, TN is $96 on 12/10/2025. Flexible travelers save on ticket prices.
Frequency of bus connections between Gainesville, FL and Knoxville, TN
Monday
is the busiest day, with more than 3 daily buses from Gainesville, FL to Knoxville, TN. Monday has instead the fewest connections, with only 3 daily coaches between Gainesville, FL and Knoxville, TN.
The busiest time of the day is the Morning, with 3 buses from Gainesville, FL to Knoxville, TN, while Morning sees the fewest connections between Gainesville, FL and Knoxville, TN, with 3 offers.
Facts about the bus from Gainesville, FL to Knoxville, TN
Compare all providers like FlixBus and Greyhound US that travel 3 times every day by bus from Gainesville, FL to Knoxville, TN in one click! Book your bus ticket from Gainesville, FL to Knoxville, TN starting from $96!
| Cheapest Bus | $96 |
| Fastest Bus | 13h 50m |
| Earliest Bus | 1:10 AM |
| Latest Bus | 10:40 PM |
| Daily Bus Routes | 3 Ø |
| Distance | 446.4 miles |
| Bus Companies | FlixBus and Greyhound US |
Cheapest bus connections from Gainesville, FL to Knoxville, TN
Every day, 3 buses from 2 bus companies leave Gainesville, FL for Knoxville, TN: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/05/2025 and for the following days.
Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday
11/30
Monday
12/01
Tuesday
12/02
Wednesday
12/03
Thursday
12/04
Friday
12/05
$128
Saturday
12/06
Sunday
12/07
Monday
12/08
$124
Tuesday
12/09
Wednesday
12/10
$96
Thursday
12/11
Friday
12/12
Saturday
12/13
Sunday
12/14
Monday
12/15
Tuesday
12/16
Wednesday
12/17
Thursday
12/18
Friday
12/19
Saturday
12/20
Sunday
12/21
Monday
12/22
Tuesday
12/23
Wednesday
12/24
Thursday
12/25
Friday
12/26
Saturday
12/27
The cheapest time to travel from Gainesville, FL to Knoxville, TN
With a price starting from $96, Wednesday is the cheapest day for a bus from Gainesville, FL to Knoxville, TN. Friday instead is the most expensive day with prices starting from $128.
Night
is the cheapest day time for bus tickets from Gainesville, FL to Knoxville, TN, with $96. Evening is the most expensive time of the day with prices starting from $101.
How to save money travelling from Gainesville, FL to Knoxville, TN
Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:
Book the ticket from Gainesville, FL to Knoxville, TN in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Gainesville, FL to Knoxville, TN, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Gainesville, FL to Knoxville, TN are also emptier.All bus stations and stops in Gainesville, FL and Knoxville, TN
In the map below, you can see where to find all bus stations in Gainesville, FL and Knoxville, TN.
Service and Comfort on the bus from Gainesville, FL to Knoxville, TN
Want to know which seat classes are available on the buses from Gainesville, FL to Knoxville, TN? Or which bus companies serve the route Gainesville, FL to Knoxville, TN? Below you will find answers to your questions.
FAQs about the Gainesville, FL to Knoxville, TN bus
How much does a Gainesville, FL Knoxville, TN bus trip cost?
This depends on, among other things, the day and time of travel. The cheapest trip is available from $96 and takes 21h 30m to reach Knoxville, TN. Compare offers to save money!
How much could I save by comparing buses from Gainesville, FL to Knoxville, TN?
This route is offered by 2 companies with a range of ticket prices between $96 and $134. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Knoxville, TN.
On average, how many connections are available from Gainesville, FL to Knoxville, TN each day?
Every day, the Gainesville, FL to Knoxville, TN bus route is served by approximately 3 connections. With our search, you can compare bus times to find the perfect trip.
How long does a bus journey from Gainesville, FL to Knoxville, TN take?
The fastest bus from Gainesville, FL to Knoxville, TN is offered by Greyhound US and takes 13h 50m. Bus tickets for this connection cost $134. In this context, bear in mind that the journey can take longer due to traffic.
What time is the first bus from Gainesville, FL to Knoxville, TN?
The earliest bus arriving in Knoxville, TN from Gainesville, FL starts at 1:10 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.
What time is the last bus from Gainesville, FL to Knoxville, TN?
The latest bus trip departing from Gainesville, FL for Knoxville, TN starts at 10:40 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.
Which bus companies operate the Gainesville, FL Knoxville, TN route?
When traveling by bus from Gainesville, FL to Knoxville, TN, passengers can travel with FlixBus and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.
Is there a direct bus between Gainesville, FL and Knoxville, TN?
You can check all the direct connections between Gainesville, FL and Knoxville, TN by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound US.
What can I take with me on the Gainesville, FL to Knoxville, TN bus route?
Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Gainesville, FL Knoxville, TN bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.
What equipment is available for the Gainesville, FL Knoxville, TN bus route?
The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Gainesville, FL to Knoxville, TN on your planned travel date.
Available seat classes which are offered on the bus route Gainesville, FL to Knoxville, TN
Economy
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
More bus routes to Gainesville, FL and to Knoxville, TN
Here’s an overview of the most popular bus routes to Gainesville, FL and to Knoxville, TN. Simply click on the connection of your choice, and you will find all the details about your bus route!
- Bus Routes to Gainesville, FL
- Bus Anniston, AL to Gainesville, FL
- Bus Ashland, KY - Gainesville, FL
- Buses to Gainesville, FL from Atlanta, GA
- From Baltimore, MD to Gainesville, FL bus
- Bus Boca Raton, FL - Gainesville, FL
- Dallas to Gainesville, FL bus
- Buses Detroit - Gainesville, FL
- From Dothan, AL to Gainesville, FL bus
- Bus Fort Lauderdale, FL to Gainesville, FL
- Buses to Gainesville, FL from Fort Worth
- Buses Louisville, KY to Gainesville, FL
- Bus from Miami to Gainesville, FL
- Ocala, FL to Gainesville, FL bus
- Buses to Gainesville, FL from Opelika, AL
- Bus from Port Saint Lucie, FL to Gainesville, FL
- Bus to Gainesville, FL from Saint Petersburg, FL
- Bus Sarasota, FL to Gainesville, FL
- Bus from Tampa to Gainesville, FL
- Bus from Valdosta, GA to Gainesville, FL
- Buses from West Palm Beach, FL to Gainesville, FL
- Bus Routes to Knoxville, TN
- Buses Atlanta, GA to Knoxville, TN
- From Birmingham, AL to Knoxville, TN bus
- Buses to Knoxville, TN from Carbondale, IL
- Buses Durham, NC - Knoxville, TN
- Bus from Fayetteville, NC to Knoxville, TN
- From Greenville, SC to Knoxville, TN bus
- Bus Henderson, NV - Knoxville, TN
- Bus from Indianapolis to Knoxville, TN
- Bus from Lexington, KY to Knoxville, TN
- Bus to Knoxville, TN from Louisville, KY
- Bus to Knoxville, TN from Macon, GA
- Buses Memphis - Knoxville, TN
- Bus Miami to Knoxville, TN
- Buses to Knoxville, TN from Nashville
- Bus to Knoxville, TN from New York
- Bus Newark - Knoxville, TN
- Bus Saint Petersburg, FL - Knoxville, TN
- Shreveport, LA to Knoxville, TN bus
- Bus to Knoxville, TN from Washington, DC
- Buses Worcester, MA to Knoxville, TN
Popular Airport Shuttles to Gainesville, FL and to Knoxville, TN
