Bus from Port Saint Lucie, FL to Gainesville, FL from $42

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Compare all timetables for the bus from Port Saint Lucie, FL to Gainesville, FL

Here is a selection of the cheapest bus trips from the schedule from Port Saint Lucie, FL to Gainesville, FL from various bus operators like FlixBus or Greyhound US for the next days.
today
tomorrow
Saturday
from $56
Sunday
from $69
Monday
Tuesday
from $42
Wednesday

Cheapest bus trips Saturday

Prices are for one way and one person
  • FlixBus
    11h 20m
    0
    3:20 AM
    Port Saint Lucie, FL
    SW Gatlin Blvd & SW Brescia St Bus Stop
    2:40 PM
    Gainesville, FL
    Rosa Parks Transfer station
    0
    FlixBus
    Economy
    $56
  • Greyhound US
    7h 40m
    0
    8:55 AM
    Port Saint Lucie, FL
    SW Gatlin Blvd & SW Brescia St Bus Stop
    4:35 PM
    Gainesville, FL
    Rosa Parks Transfer station
    0
    Greyhound US
    Economy
    $56
  • FlixBus
    6h 50m
    0
    1:40 AM
    Port Saint Lucie, FL
    SW Gatlin Blvd & SW Brescia St Bus Stop
    8:30 AM
    Gainesville, FL
    Rosa Parks Transfer station
    0
    FlixBus
    Economy
    $58
  • FlixBus
    6h 10m
    0
    1:40 AM
    Port Saint Lucie, FL
    SW Gatlin Blvd & SW Brescia St Bus Stop
    7:50 AM
    Gainesville, FL
    North Walmart Supercenter Bus Stop
    0
    FlixBus
    Economy
    $58
  • Greyhound US
    7h 40m
    0
    8:55 AM
    Port Saint Lucie, FL
    RaceTrac Gas Station
    4:35 PM
    Gainesville, FL
    Rosa Parks Transfer station
    0
    Greyhound US
    Economy
    $60

Cheapest bus trips Sunday

Prices are for one way and one person
  • FlixBus
    6h 10m
    0
    1:40 AM
    Port Saint Lucie, FL
    RaceTrac Gas Station
    7:50 AM
    Gainesville, FL
    Greyhound Bus Station
    0
    FlixBus
    Economy
    $69
  • FlixBus
    6h 50m
    0
    1:40 AM
    Port Saint Lucie, FL
    RaceTrac Gas Station
    8:30 AM
    Gainesville, FL
    Rosa Parks Transfer station
    0
    FlixBus
    Economy
    $69
  • FlixBus
    11h 20m
    0
    3:20 AM
    Port Saint Lucie, FL
    RaceTrac Gas Station
    2:40 PM
    Gainesville, FL
    Rosa Parks Transfer station
    0
    FlixBus
    Economy
    $69
  • Greyhound US
    7h 40m
    0
    8:55 AM
    Port Saint Lucie, FL
    RaceTrac Gas Station
    4:35 PM
    Gainesville, FL
    Rosa Parks Transfer station
    0
    Greyhound US
    Economy
    $69
  • Did you know that if you travel from Port Saint Lucie, FL to Gainesville, FL via Orlando, FL, you can save more than $14? You can find the corresponding connections below.
    • Busbud
      5h 45m
      0
      8:05 AM
      Port Saint Lucie, FL
      Fort Pierce Service Plaza
      10:00 AM
      Orlando, FL
      Jet Set Express Orlando Terminal
      0
      Busbud
      Economy
      $22
      • Waiting Time 1h 50m
    • Busbud
      2h 0m
      0
      11:50 AM
      Orlando, FL
      Bus Station
      1:50 PM
      Gainesville, FL
      Rosa Parks Transfer station
      0
      Busbud
      Economy
      $33
    Travel Time is 0h 25m shorter, and you will save $14

Cheapest bus trips Tuesday

Prices are for one way and one person
  • FlixBus
    6h 10m
    0
    1:40 AM
    Port Saint Lucie, FL
    RaceTrac Gas Station
    7:50 AM
    Gainesville, FL
    Greyhound Bus Station
    0
    FlixBus
    Economy
    $42
  • FlixBus
    9h 45m
    0
    1:40 AM
    Port Saint Lucie, FL
    RaceTrac Gas Station
    11:25 AM
    Gainesville, FL
    Rosa Parks Transfer station
    0
    FlixBus
    Economy
    $42
  • FlixBus
    11h 20m
    0
    3:20 AM
    Port Saint Lucie, FL
    RaceTrac Gas Station
    2:40 PM
    Gainesville, FL
    Rosa Parks Transfer station
    0
    FlixBus
    Economy
    $42
  • Greyhound US
    8h 15m
    0
    8:55 AM
    Port Saint Lucie, FL
    RaceTrac Gas Station
    5:10 PM
    Gainesville, FL
    Rosa Parks Transfer station
    0
    Greyhound US
    Economy
    $42

Frequency of bus connections between Port Saint Lucie, FL and Gainesville, FL

See here how frequent the connections between Port Saint Lucie, FL and Gainesville, FL are, during different times and days of the week.
Saturday is the busiest day, with more than 8 daily buses from Port Saint Lucie, FL to Gainesville, FL. Sunday has instead the fewest connections, with only 4 daily coaches between Port Saint Lucie, FL and Gainesville, FL.
The busiest time of the day is the Night, with 12 buses from Port Saint Lucie, FL to Gainesville, FL, while Morning sees the fewest connections between Port Saint Lucie, FL and Gainesville, FL, with 4 offers.

Facts about the bus from Port Saint Lucie, FL to Gainesville, FL

Compare all providers like FlixBus and Greyhound US that travel 5 times every day by bus from Port Saint Lucie, FL to Gainesville, FL in one click! Book your bus ticket from Port Saint Lucie, FL to Gainesville, FL starting from $42!

Cheapest Bus $42
Fastest Bus 6h 10m
Earliest Bus 1:40 AM
Latest Bus 8:55 AM
Daily Bus Routes 5 Ø
Distance 202.8 miles
Bus Companies FlixBus and Greyhound US

Cheapest bus connections from Port Saint Lucie, FL to Gainesville, FL

Every day, 5 buses from 2 bus companies leave Port Saint Lucie, FL for Gainesville, FL: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 05/22/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 05/18
Monday 05/19
Tuesday 05/20
Wednesday 05/21
Thursday 05/22
Friday 05/23
Saturday 05/24
$60
Sunday 05/25
$69
Monday 05/26
Tuesday 05/27
$42
Wednesday 05/28
Thursday 05/29
$48
Friday 05/30
Saturday 05/31
Sunday 06/01
Monday 06/02
Tuesday 06/03
Wednesday 06/04
Thursday 06/05
Friday 06/06
Saturday 06/07
Sunday 06/08
Monday 06/09
Tuesday 06/10
Wednesday 06/11
Thursday 06/12
Friday 06/13
Saturday 06/14

The cheapest time to travel from Port Saint Lucie, FL to Gainesville, FL

See here on which day and which time of the day you can find the cheapest bus ticket from Port Saint Lucie, FL to Gainesville, FL, for the next 30 days.
With a price starting from $42, Tuesday is the cheapest day for a bus from Port Saint Lucie, FL to Gainesville, FL. Sunday instead is the most expensive day with prices starting from $69.
Morning is the cheapest day time for bus tickets from Port Saint Lucie, FL to Gainesville, FL, with $42. Morning is the most expensive time of the day with prices starting from $42.

How to save money travelling from Port Saint Lucie, FL to Gainesville, FL

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Port Saint Lucie, FL to Gainesville, FL in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Port Saint Lucie, FL to Gainesville, FL, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Port Saint Lucie, FL to Gainesville, FL are also emptier.

All bus stations and stops in Port Saint Lucie, FL and Gainesville, FL

In the map below, you can see where to find all bus stations in Port Saint Lucie, FL and Gainesville, FL.

Service and Comfort on the bus from Port Saint Lucie, FL to Gainesville, FL

Want to know which seat classes are available on the buses from Port Saint Lucie, FL to Gainesville, FL? Or which bus companies serve the route Port Saint Lucie, FL to Gainesville, FL? Below you will find answers to your questions.

FAQs about the Port Saint Lucie, FL to Gainesville, FL bus

How much does a Port Saint Lucie, FL Gainesville, FL bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $42 and takes 11h 20m to reach Gainesville, FL. Compare offers to save money!

How much could I save by comparing buses from Port Saint Lucie, FL to Gainesville, FL?

This route is offered by 2 companies with a range of ticket prices between $42 and $69. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Gainesville, FL.

On average, how many connections are available from Port Saint Lucie, FL to Gainesville, FL each day?

Every day, the Port Saint Lucie, FL to Gainesville, FL bus route is served by approximately 5 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Port Saint Lucie, FL to Gainesville, FL take?

The fastest bus from Port Saint Lucie, FL to Gainesville, FL is offered by FlixBus and takes 6h 10m. Bus tickets for this connection cost $58. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Port Saint Lucie, FL to Gainesville, FL?

The earliest bus arriving in Gainesville, FL from Port Saint Lucie, FL starts at 1:40 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Port Saint Lucie, FL to Gainesville, FL?

The latest bus trip departing from Port Saint Lucie, FL for Gainesville, FL starts at 8:55 AM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Port Saint Lucie, FL Gainesville, FL route?

When traveling by bus from Port Saint Lucie, FL to Gainesville, FL, passengers can travel with FlixBus and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Port Saint Lucie, FL and Gainesville, FL?

You can check all the direct connections between Port Saint Lucie, FL and Gainesville, FL by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound US.

What can I take with me on the Port Saint Lucie, FL to Gainesville, FL bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Port Saint Lucie, FL Gainesville, FL bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Port Saint Lucie, FL Gainesville, FL bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Port Saint Lucie, FL to Gainesville, FL on your planned travel date.

Available seat classes which are offered on the bus route Port Saint Lucie, FL to Gainesville, FL

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Port Saint Lucie, FL and to Gainesville, FL

Here’s an overview of the most popular bus routes to Port Saint Lucie, FL and to Gainesville, FL. Simply click on the connection of your choice, and you will find all the details about your bus route!
Bus Orlando, FL to Port Saint Lucie, FL Bus Orlando, FL to Port Saint Lucie, FL
Bus Miami to Port Saint Lucie, FL Bus Miami to Port Saint Lucie, FL
Bus to Port Saint Lucie, FL from West Palm Beach, FL Bus to Port Saint Lucie, FL from West Palm Beach, FL
Bus Tampa to Port Saint Lucie, FL Bus Tampa to Port Saint Lucie, FL
Bus from Miami to Gainesville, FL Bus from Miami to Gainesville, FL
Bus Ocala, FL - Gainesville, FL Bus Ocala, FL - Gainesville, FL
Buses West Palm Beach, FL to Gainesville, FL Buses West Palm Beach, FL to Gainesville, FL
Fort Lauderdale, FL to Gainesville, FL bus Fort Lauderdale, FL to Gainesville, FL bus
Popular Airport Shuttles to Port Saint Lucie, FL and to Gainesville, FL
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