Bus from Orlando, FL to Knoxville, TN from $99

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Compare all timetables for the bus from Orlando, FL to Knoxville, TN

Here is a selection of the cheapest bus trips from the schedule from Orlando, FL to Knoxville, TN from various bus operators like FlixBus for the next days.

today
$147
tomorrow
Sunday
Monday
$134
Tuesday
$127
Wednesday
Thursday

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 30h 10m 3:40 PM Orlando, FL Bus Station 9:50 PM Knoxville, TN Greyhound Bus Station  Economy $147
FlixBus 23h 45m 10:55 PM Orlando, FL Bus Station 10:40 PM Knoxville, TN Greyhound Bus Station  Economy $147

Cheapest bus trips Monday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 15h 50m 6:00 AM Orlando, FL Bus Station 9:50 PM Knoxville, TN Knoxville Area Transit Bus Stop  Economy $134
FlixBus 23h 45m 10:55 PM Orlando, FL Bus Station 10:40 PM Knoxville, TN Knoxville Area Transit Bus Stop  Economy $134
FlixBus 30h 10m 3:40 PM Orlando, FL Bus Station 9:50 PM Knoxville, TN Knoxville Area Transit Bus Stop  Economy $146
  • Did you know that if you travel from Orlando, FL to Knoxville, TN via Atlanta, GA, you can save more than $20? You can find the corresponding connections below.
    • Busbud
      22h 55m
      0
      10:55 PM
      Orlando, FL
      Bus Station
      7:15 AM
      Atlanta, GA
      Garnett Transit Station
      0
      Busbud
      Economy
      $67
      • Waiting Time 10h 50m
    • FlixBus
      3h 45m
      0
      6:05 PM
      Atlanta, GA
      Garnett Transit Station
      9:50 PM
      Knoxville, TN
      Greyhound Bus Station
      0
      FlixBus
      Economy
      $47
    Travel time is 7h 5m longer, but you will save $20

Cheapest bus trips Tuesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 23h 45m 10:55 PM Orlando, FL Bus Station 10:40 PM Knoxville, TN Greyhound Bus Station  Economy $127
FlixBus 30h 10m 3:40 PM Orlando, FL Bus Station 9:50 PM Knoxville, TN Greyhound Bus Station  Economy $167
FlixBus 15h 50m 6:00 AM Orlando, FL Bus Station 9:50 PM Knoxville, TN Greyhound Bus Station  Economy $176
  • Did you know that if you travel from Orlando, FL to Knoxville, TN via Atlanta, GA, you can save more than $13? You can find the corresponding connections below.
    • Busbud
      22h 55m
      0
      10:55 PM
      Orlando, FL
      Bus Station
      7:15 AM
      Atlanta, GA
      Garnett Transit Station
      0
      Busbud
      Economy
      $67
      • Waiting Time 10h 50m
    • FlixBus
      3h 45m
      0
      6:05 PM
      Atlanta, GA
      Garnett Transit Station
      9:50 PM
      Knoxville, TN
      Greyhound Bus Station
      0
      FlixBus
      Economy
      $47
    Travel time is 7h 5m longer, but you will save $13

Best Price Offer: The price for the cheapest bus from Orlando, FL to Knoxville, TN is $99 on 1/9/2026. Flexible travelers save on ticket prices.


Frequency of bus connections between Orlando, FL and Knoxville, TN

See here how frequent the connections between Orlando, FL and Knoxville, TN are, during different times and days of the week.
Monday is the busiest day, with more than 6 daily buses from Orlando, FL to Knoxville, TN. Friday has instead the fewest connections, with only 2 daily coaches between Orlando, FL and Knoxville, TN.
The busiest time of the day is the Afternoon, with 4 buses from Orlando, FL to Knoxville, TN, while Morning sees the fewest connections between Orlando, FL and Knoxville, TN, with 3 offers.

Facts about the bus from Orlando, FL to Knoxville, TN

Compare all providers like FlixBus that travel 3 times every day by bus from Orlando, FL to Knoxville, TN in one click! Book your bus ticket from Orlando, FL to Knoxville, TN starting from $99!

Cheapest Bus $99
Fastest Bus 15h 50m
Earliest Bus 3:40 PM
Latest Bus 10:55 PM
Daily Bus Routes 3 Ø
Distance 534.0 miles
Bus Companies FlixBus

Cheapest bus connections from Orlando, FL to Knoxville, TN

Every day, 3 buses from 1 bus companies leave Orlando, FL for Knoxville, TN: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/19/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 12/14
Monday 12/15
Tuesday 12/16
Wednesday 12/17
Thursday 12/18
Friday 12/19
$136
Saturday 12/20
Sunday 12/21
Monday 12/22
$134
Tuesday 12/23
$127
Wednesday 12/24
Thursday 12/25
Friday 12/26
$148
Saturday 12/27
Sunday 12/28
$122
Monday 12/29
$120
Tuesday 12/30
$127
Wednesday 12/31
Thursday 01/01
Friday 01/02
Saturday 01/03
Sunday 01/04
Monday 01/05
$116
Tuesday 01/06
Wednesday 01/07
Thursday 01/08
Friday 01/09
$99
Saturday 01/10

The cheapest time to travel from Orlando, FL to Knoxville, TN

See here on which day and which time of the day you can find the cheapest bus ticket from Orlando, FL to Knoxville, TN, for the next 30 days.
With a price starting from $91, Monday is the cheapest day for a bus from Orlando, FL to Knoxville, TN. Tuesday instead is the most expensive day with prices starting from $127.
Evening is the cheapest day time for bus tickets from Orlando, FL to Knoxville, TN, with $127. Afternoon is the most expensive time of the day with prices starting from $146.

How to save money travelling from Orlando, FL to Knoxville, TN

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Orlando, FL to Knoxville, TN in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Orlando, FL to Knoxville, TN, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Orlando, FL to Knoxville, TN are also emptier.

Beloved bus companies from Orlando, FL to Knoxville, TN

These are the most booked bus companies between Orlando, FL to Knoxville, TN from our users.

FlixBus from Orlando, FL to Knoxville, TN

FlixBus

Here you will find the key facts about the FlixBus bus route Orlando, FL to Knoxville, TN:

Cheapest Price $127
Fastest Bus 15h 50m
Earliest Bus 3:40 PM
Last Bus 10:55 PM
Daily Connections 3 Ø
Found on 12/14/2025

All bus stations and stops in Orlando, FL and Knoxville, TN

In the map below, you can see where to find all bus stations in Orlando, FL and Knoxville, TN.

Service and Comfort on the bus from Orlando, FL to Knoxville, TN

Want to know which seat classes are available on the buses from Orlando, FL to Knoxville, TN? Or which bus companies serve the route Orlando, FL to Knoxville, TN? Below you will find answers to your questions.

FAQs about the Orlando, FL to Knoxville, TN bus

How much does a Orlando, FL Knoxville, TN bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $99 and takes 23h 45m to reach Knoxville, TN. Compare offers to save money!

How much could I save by comparing buses from Orlando, FL to Knoxville, TN?

This route is offered by 1 companies with a range of ticket prices between $99 and $176. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Knoxville, TN.

On average, how many connections are available from Orlando, FL to Knoxville, TN each day?

Every day, the Orlando, FL to Knoxville, TN bus route is served by approximately 3 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Orlando, FL to Knoxville, TN take?

The fastest bus from Orlando, FL to Knoxville, TN is offered by FlixBus and takes 15h 50m. Bus tickets for this connection cost $138. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Orlando, FL to Knoxville, TN?

The earliest bus arriving in Knoxville, TN from Orlando, FL starts at 3:40 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Orlando, FL to Knoxville, TN?

The latest bus trip departing from Orlando, FL for Knoxville, TN starts at 10:55 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Orlando, FL Knoxville, TN route?

When traveling by bus from Orlando, FL to Knoxville, TN, passengers can travel with FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Orlando, FL and Knoxville, TN?

You can check all the direct connections between Orlando, FL and Knoxville, TN by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus.

What can I take with me on the Orlando, FL to Knoxville, TN bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Orlando, FL Knoxville, TN bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Orlando, FL Knoxville, TN bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Orlando, FL to Knoxville, TN on your planned travel date.

How does CheckMyBus find the best bus deals from Orlando, FL to Knoxville, TN?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 3 daily trips between Orlando, FL and Knoxville, TN. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Orlando, FL to Knoxville, TN?

Prices and availability for 3 trips between Orlando, FL and Knoxville, TN change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Orlando, FL to Knoxville, TN

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Orlando, FL and to Knoxville, TN

Here’s an overview of the most popular bus routes to Orlando, FL and to Knoxville, TN. Simply click on the connection of your choice, and you will find all the details about your bus route!
Buses New Orleans, LA - Orlando, FL Buses New Orleans, LA - Orlando, FL
Bus Nashville - Orlando, FL Bus Nashville - Orlando, FL
Bus Miami - Orlando, FL Bus Miami - Orlando, FL
From Tampa to Orlando, FL bus From Tampa to Orlando, FL bus
Buses to Knoxville, TN from Philadelphia Buses to Knoxville, TN from Philadelphia
Bus Dallas - Knoxville, TN Bus Dallas - Knoxville, TN
Buses Houston - Knoxville, TN Buses Houston - Knoxville, TN
Buses from Athens, TN to Knoxville, TN Buses from Athens, TN to Knoxville, TN
Popular Airport Shuttles to Orlando, FL and to Knoxville, TN
CheckMyBus › Buses in USA › Bus to Orlando, FL › Bus to Knoxville, TN

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