Bus Los Angeles to Knoxville, TN: Compare prices and save money

Compare all timetables for the bus from Los Angeles to Knoxville, TN

Here is a selection of the cheapest bus trips from the schedule from Los Angeles to Knoxville, TN from various bus operators like FlixBus or Greyhound US for the next days.

today

tomorrow

Friday

Saturday

Sunday

$306

Monday

Tuesday

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	53h 55m	12:55 PM	Los Angeles	Union Station	9:50 PM	Knoxville, TN	Greyhound Bus Station	Economy	$306	A Bus from Greyhound US goes from Union Station, Los Angeles (USA) at 12/28/2025 12:55:00 PM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 12/30/2025 9:50:00 PM. 50 Economy ticket for $306 per person are available. Travel duration is 53h 55m
FlixBus	54h 20m	1:20 PM	Los Angeles	Union Station	10:40 PM	Knoxville, TN	Greyhound Bus Station	Economy	$313	A Bus from FlixBus goes from Union Station, Los Angeles (USA) at 12/28/2025 1:20:00 PM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 12/30/2025 10:40:00 PM. 50 Economy ticket for $313 per person are available. Travel duration is 54h 20m
Greyhound US	47h 10m	8:30 PM	Los Angeles	Union Station	10:40 PM	Knoxville, TN	Greyhound Bus Station	Economy	$315	A Bus from Greyhound US goes from Union Station, Los Angeles (USA) at 12/28/2025 8:30:00 PM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 12/30/2025 10:40:00 PM. 50 Economy ticket for $315 per person are available. Travel duration is 47h 10m
FlixBus	57h 15m	9:35 AM	Los Angeles	Union Station	9:50 PM	Knoxville, TN	Greyhound Bus Station	Economy	$492	A Bus from FlixBus goes from Union Station, Los Angeles (USA) at 12/28/2025 9:35:00 AM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 12/30/2025 9:50:00 PM. 50 Economy ticket for $492 per person are available. Travel duration is 57h 15m

Best Price Offer: The price for the cheapest bus from Los Angeles to Knoxville, TN is $178 on 1/6/2026. Flexible travelers save on ticket prices.

Facts about the bus from Los Angeles to Knoxville, TN

Compare all providers like FlixBus and Greyhound US that travel 4 times every day by bus from Los Angeles to Knoxville, TN in one click! Book your bus ticket from Los Angeles to Knoxville, TN starting from $178!

Cheapest Bus	$178
Fastest Bus	50h 10m
Earliest Bus	9:35 AM
Latest Bus	8:30 PM
Daily Bus Routes	4 Ø
Distance	1,937.3 miles
Bus Companies	FlixBus and Greyhound US

Cheapest bus connections from Los Angeles to Knoxville, TN

Every day, 4 buses from 2 bus companies leave Los Angeles for Knoxville, TN: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/24/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 12/21

Monday 12/22

Tuesday 12/23

Wednesday 12/24

Thursday 12/25

Friday 12/26

Saturday 12/27

Sunday 12/28

$306

Monday 12/29

Tuesday 12/30

Wednesday 12/31

$205

Thursday 01/01

Friday 01/02

Saturday 01/03

Sunday 01/04

Monday 01/05

Tuesday 01/06

$178

Wednesday 01/07

Thursday 01/08

Friday 01/09

Saturday 01/10

Sunday 01/11

Monday 01/12

Tuesday 01/13

Wednesday 01/14

Thursday 01/15

Friday 01/16

Saturday 01/17

How to save money travelling from Los Angeles to Knoxville, TN

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Los Angeles to Knoxville, TN in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Los Angeles to Knoxville, TN, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Los Angeles to Knoxville, TN are also emptier.

Beloved bus companies from Los Angeles to Knoxville, TN

These are the most booked bus companies between Los Angeles to Knoxville, TN from our users.

Greyhound US from Los Angeles to Knoxville, TN

Here you will find the key facts about the Greyhound US bus route Los Angeles to Knoxville, TN:

Cheapest Price	$306
Fastest Bus	50h 10m
Earliest Bus	12:55 PM
Last Bus	8:30 PM
Daily Connections	2 Ø
Found on	12/19/2025

All bus stations and stops in Los Angeles and Knoxville, TN

In the map below, you can see where to find all bus stations in Los Angeles and Knoxville, TN.

Downtown Bus Station

N Main St 512

Las Casas

Main Street 94

Tufesa

Maple Ave 611

Union Station

Ramirez Street 401-479

Amtrak

Alameda Street 738-788

Kingston Pike

Kingston Pike 6927

Knoxville Area Transit Bus Stop

Knoxville Area Transit Bus Stop Knoxville Area Transit Bus Stop

Walker Springs Plaza Shopping Center

Kingston Pike 8509

Greyhound Bus Station

E Magnolia Ave 100

Transit Center

E Church Ave 301

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Los Angeles to Knoxville, TN? Compare all modes of transports from Los Angeles to Knoxville, TN.

Service and Comfort on the bus from Los Angeles to Knoxville, TN

Want to know which seat classes are available on the buses from Los Angeles to Knoxville, TN? Or which bus companies serve the route Los Angeles to Knoxville, TN? Below you will find answers to your questions.

FAQs about the Los Angeles to Knoxville, TN bus

How much does a Los Angeles Knoxville, TN bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $178 and takes 56h 55m to reach Knoxville, TN. Compare offers to save money!

How much could I save by comparing buses from Los Angeles to Knoxville, TN?

This route is offered by 2 companies with a range of ticket prices between $178 and $492. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Knoxville, TN.

On average, how many connections are available from Los Angeles to Knoxville, TN each day?

Every day, the Los Angeles to Knoxville, TN bus route is served by approximately 4 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Los Angeles to Knoxville, TN take?

The fastest bus from Los Angeles to Knoxville, TN is offered by Greyhound US and takes 50h 10m. Bus tickets for this connection cost $315. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Los Angeles to Knoxville, TN?

The earliest bus arriving in Knoxville, TN from Los Angeles starts at 9:35 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Los Angeles to Knoxville, TN?

The latest bus trip departing from Los Angeles for Knoxville, TN starts at 8:30 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Los Angeles Knoxville, TN route?

When traveling by bus from Los Angeles to Knoxville, TN, passengers can travel with FlixBus and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Los Angeles and Knoxville, TN?

You can check all the direct connections between Los Angeles and Knoxville, TN by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound US.

What can I take with me on the Los Angeles to Knoxville, TN bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Los Angeles Knoxville, TN bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Los Angeles Knoxville, TN bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Los Angeles to Knoxville, TN on your planned travel date.

How does CheckMyBus find the best bus deals from Los Angeles to Knoxville, TN?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 4 daily trips between Los Angeles and Knoxville, TN. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Los Angeles to Knoxville, TN?

Prices and availability for 4 trips between Los Angeles and Knoxville, TN change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Los Angeles to Knoxville, TN

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Los Angeles and to Knoxville, TN

Here’s an overview of the most popular bus routes to Los Angeles and to Knoxville, TN. Simply click on the connection of your choice, and you will find all the details about your bus route!