Bus Philadelphia to Knoxville, TN: Compare prices and save money

Compare all timetables for the bus from Philadelphia to Knoxville, TN

Here is a selection of the cheapest bus trips from the schedule from Philadelphia to Knoxville, TN from various bus operators like FlixBus or Greyhound US for the next days.

today

from $86

tomorrow

Monday

from $84

Tuesday

from $79

Wednesday

Thursday

from $74

Friday

Cheapest bus trips today

Prices are for one way and one person

FlixBus

16h 10m

0

1:55 AM

Philadelphia
Spring Garden St & 2nd St Bus Stop

6:05 PM

Knoxville, TN
Greyhound Bus Station

0

Economy

$86

A Bus from FlixBus goes from Spring Garden St & 2nd St Bus Stop, Philadelphia (USA) at 5/17/2025 1:55:00 AM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 5/17/2025 6:05:00 PM. 50 Economy ticket for $86 per person are available. Travel duration is 16h 10m
Greyhound US

21h 35m

0

8:30 PM

Philadelphia
Spring Garden St & 2nd St Bus Stop

6:05 PM

Knoxville, TN
Greyhound Bus Station

0

Economy

$86

A Bus from Greyhound US goes from Spring Garden St & 2nd St Bus Stop, Philadelphia (USA) at 5/17/2025 8:30:00 PM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 5/18/2025 6:05:00 PM. 50 Economy ticket for $86 per person are available. Travel duration is 21h 35m
Greyhound US

22h 5m

0

8:00 PM

Philadelphia
IRS Building

6:05 PM

Knoxville, TN
Greyhound Bus Station

0

Economy

$105

A Bus from Greyhound US goes from IRS Building, Philadelphia (USA) at 5/17/2025 8:00:00 PM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 5/18/2025 6:05:00 PM. 50 Economy ticket for $105 per person are available. Travel duration is 22h 5m
FlixBus

21h 20m

0

8:45 PM

Philadelphia
Spring Garden St & 2nd St Bus Stop

6:05 PM

Knoxville, TN
Greyhound Bus Station

0

Economy

$107

A Bus from FlixBus goes from Spring Garden St & 2nd St Bus Stop, Philadelphia (USA) at 5/17/2025 8:45:00 PM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 5/18/2025 6:05:00 PM. 50 Economy ticket for $107 per person are available. Travel duration is 21h 20m
FlixBus

21h 50m

0

8:15 PM

Philadelphia
JFK & Broad

6:05 PM

Knoxville, TN
Greyhound Bus Station

0

Economy

$109

A Bus from FlixBus goes from JFK & Broad, Philadelphia (USA) at 5/17/2025 8:15:00 PM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 5/18/2025 6:05:00 PM. 50 Economy ticket for $109 per person are available. Travel duration is 21h 50m

Cheapest bus trips Monday

Prices are for one way and one person

FlixBus

21h 20m

0

8:45 PM

Philadelphia
Spring Garden St & 2nd St Bus Stop

6:05 PM

Knoxville, TN
Greyhound Bus Station

0

Economy

$84

A Bus from FlixBus goes from Spring Garden St & 2nd St Bus Stop, Philadelphia (USA) at 5/19/2025 8:45:00 PM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 5/20/2025 6:05:00 PM. 50 Economy ticket for $84 per person are available. Travel duration is 21h 20m
Greyhound US

22h 5m

0

8:00 PM

Philadelphia
IRS Building

6:05 PM

Knoxville, TN
Greyhound Bus Station

0

Economy

$85

A Bus from Greyhound US goes from IRS Building, Philadelphia (USA) at 5/19/2025 8:00:00 PM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 5/20/2025 6:05:00 PM. 50 Economy ticket for $85 per person are available. Travel duration is 22h 5m
FlixBus

16h 10m

0

1:55 AM

Philadelphia
Spring Garden St & 2nd St Bus Stop

6:05 PM

Knoxville, TN
Greyhound Bus Station

0

Economy

$86

A Bus from FlixBus goes from Spring Garden St & 2nd St Bus Stop, Philadelphia (USA) at 5/19/2025 1:55:00 AM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 5/19/2025 6:05:00 PM. 50 Economy ticket for $86 per person are available. Travel duration is 16h 10m
Greyhound US

21h 35m

0

8:30 PM

Philadelphia
Spring Garden St & 2nd St Bus Stop

6:05 PM

Knoxville, TN
Greyhound Bus Station

0

Economy

$86

A Bus from Greyhound US goes from Spring Garden St & 2nd St Bus Stop, Philadelphia (USA) at 5/19/2025 8:30:00 PM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 5/20/2025 6:05:00 PM. 50 Economy ticket for $86 per person are available. Travel duration is 21h 35m

Cheapest bus trips Tuesday

Prices are for one way and one person

Greyhound US

22h 5m

0

8:00 PM

Philadelphia
IRS Building

6:05 PM

Knoxville, TN
Greyhound Bus Station

0

Economy

$79

A Bus from Greyhound US goes from IRS Building, Philadelphia (USA) at 5/20/2025 8:00:00 PM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 5/21/2025 6:05:00 PM. 50 Economy ticket for $79 per person are available. Travel duration is 22h 5m
FlixBus

16h 20m

0

1:45 AM

Philadelphia
Spring Garden St & 2nd St Bus Stop

6:05 PM

Knoxville, TN
Greyhound Bus Station

0

Economy

$80

A Bus from FlixBus goes from Spring Garden St & 2nd St Bus Stop, Philadelphia (USA) at 5/20/2025 1:45:00 AM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 5/20/2025 6:05:00 PM. 50 Economy ticket for $80 per person are available. Travel duration is 16h 20m
Greyhound US

21h 35m

0

8:30 PM

Philadelphia
Spring Garden St & 2nd St Bus Stop

6:05 PM

Knoxville, TN
Greyhound Bus Station

0

Economy

$80

A Bus from Greyhound US goes from Spring Garden St & 2nd St Bus Stop, Philadelphia (USA) at 5/20/2025 8:30:00 PM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 5/21/2025 6:05:00 PM. 50 Economy ticket for $80 per person are available. Travel duration is 21h 35m
FlixBus

31h 45m

0

10:20 AM

Philadelphia
JFK & Broad

6:05 PM

Knoxville, TN
Greyhound Bus Station

0

Economy

$81

A Bus from FlixBus goes from JFK & Broad, Philadelphia (USA) at 5/20/2025 10:20:00 AM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 5/21/2025 6:05:00 PM. 50 Economy ticket for $81 per person are available. Travel duration is 31h 45m
FlixBus

23h 20m

0

6:45 PM

Philadelphia
Spring Garden St & 2nd St Bus Stop

6:05 PM

Knoxville, TN
Greyhound Bus Station

0

Economy

$82

A Bus from FlixBus goes from Spring Garden St & 2nd St Bus Stop, Philadelphia (USA) at 5/20/2025 6:45:00 PM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 5/21/2025 6:05:00 PM. 50 Economy ticket for $82 per person are available. Travel duration is 23h 20m

Cheapest bus trips Thursday

Prices are for one way and one person

Greyhound US

21h 35m

0

8:30 PM

Philadelphia
Spring Garden St & 2nd St Bus Stop

6:05 PM

Knoxville, TN
Greyhound Bus Station

0

Economy

$74

A Bus from Greyhound US goes from Spring Garden St & 2nd St Bus Stop, Philadelphia (USA) at 5/22/2025 8:30:00 PM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 5/23/2025 6:05:00 PM. 50 Economy ticket for $74 per person are available. Travel duration is 21h 35m
FlixBus

16h 10m

0

1:55 AM

Philadelphia
Spring Garden St & 2nd St Bus Stop

6:05 PM

Knoxville, TN
Greyhound Bus Station

0

Economy

$82

A Bus from FlixBus goes from Spring Garden St & 2nd St Bus Stop, Philadelphia (USA) at 5/22/2025 1:55:00 AM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 5/22/2025 6:05:00 PM. 50 Economy ticket for $82 per person are available. Travel duration is 16h 10m
FlixBus

21h 20m

0

8:45 PM

Philadelphia
Spring Garden St & 2nd St Bus Stop

6:05 PM

Knoxville, TN
Greyhound Bus Station

0

Economy

$106

A Bus from FlixBus goes from Spring Garden St & 2nd St Bus Stop, Philadelphia (USA) at 5/22/2025 8:45:00 PM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 5/23/2025 6:05:00 PM. 50 Economy ticket for $106 per person are available. Travel duration is 21h 20m
FlixBus

21h 50m

0

8:15 PM

Philadelphia
JFK & Broad

6:05 PM

Knoxville, TN
Greyhound Bus Station

0

Economy

$107

A Bus from FlixBus goes from JFK & Broad, Philadelphia (USA) at 5/22/2025 8:15:00 PM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 5/23/2025 6:05:00 PM. 50 Economy ticket for $107 per person are available. Travel duration is 21h 50m
Greyhound US

22h 5m

0

8:00 PM

Philadelphia
IRS Building

6:05 PM

Knoxville, TN
Greyhound Bus Station

0

Economy

$108

A Bus from Greyhound US goes from IRS Building, Philadelphia (USA) at 5/22/2025 8:00:00 PM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 5/23/2025 6:05:00 PM. 50 Economy ticket for $108 per person are available. Travel duration is 22h 5m

Frequency of bus connections between Philadelphia and Knoxville, TN

See here how frequent the connections between Philadelphia and Knoxville, TN are, during different times and days of the week.

Tuesday is the busiest day, with more than 5 daily buses from Philadelphia to Knoxville, TN. Monday has instead the fewest connections, with only 4 daily coaches between Philadelphia and Knoxville, TN.

The busiest time of the day is the Evening, with 14 buses from Philadelphia to Knoxville, TN, while Morning sees the fewest connections between Philadelphia and Knoxville, TN, with 1 offers.

Facts about the bus from Philadelphia to Knoxville, TN

Compare all providers like FlixBus and Greyhound US that travel 4 times every day by bus from Philadelphia to Knoxville, TN in one click! Book your bus ticket from Philadelphia to Knoxville, TN starting from $74!

Cheapest Bus	$74
Fastest Bus	16h 10m
Earliest Bus	1:55 AM
Latest Bus	8:45 PM
Daily Bus Routes	4 Ø
Distance	549.6 miles
Bus Companies	FlixBus and Greyhound US

Cheapest bus connections from Philadelphia to Knoxville, TN

Every day, 4 buses from 2 bus companies leave Philadelphia for Knoxville, TN: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 05/17/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 05/11

Monday 05/12

Tuesday 05/13

Wednesday 05/14

Thursday 05/15

Friday 05/16

Saturday 05/17

$86

Sunday 05/18

Monday 05/19

$84

Tuesday 05/20

$79

Wednesday 05/21

Thursday 05/22

$74

Friday 05/23

$77

Saturday 05/24

$74

Sunday 05/25

$113

Monday 05/26

Tuesday 05/27

Wednesday 05/28

Thursday 05/29

Friday 05/30

$87

Saturday 05/31

Sunday 06/01

Monday 06/02

Tuesday 06/03

Wednesday 06/04

Thursday 06/05

Friday 06/06

Saturday 06/07

The cheapest time to travel from Philadelphia to Knoxville, TN

See here on which day and which time of the day you can find the cheapest bus ticket from Philadelphia to Knoxville, TN, for the next 30 days.

With a price starting from $74, Thursday is the cheapest day for a bus from Philadelphia to Knoxville, TN. Saturday instead is the most expensive day with prices starting from $86.

Evening is the cheapest day time for bus tickets from Philadelphia to Knoxville, TN, with $74. Night is the most expensive time of the day with prices starting from $80.

How to save money travelling from Philadelphia to Knoxville, TN

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Philadelphia to Knoxville, TN in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Philadelphia to Knoxville, TN, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Philadelphia to Knoxville, TN are also emptier.

Beloved bus companies from Philadelphia to Knoxville, TN

These are the most booked bus companies between Philadelphia to Knoxville, TN from our users.

FlixBus from Philadelphia to Knoxville, TN

Here you will find the key facts about the FlixBus bus route Philadelphia to Knoxville, TN:

Cheapest Price	$80
Fastest Bus	16h 10m
Earliest Bus	1:55 AM
Last Bus	8:45 PM
Daily Connections	2 Ø
Found on	5/13/2025

All bus stations and stops in Philadelphia and Knoxville, TN

In the map below, you can see where to find all bus stations in Philadelphia and Knoxville, TN.

Central Bus Station

Filbert St 1001

Market St

30th Street Station

Market St 2955

Philadelphia, PA

NRG/AT&T Subway Station

S Broad St 3701

Kingston Pike

Kingston Pike 6927

Walker Springs Plaza Shopping Center

Kingston Pike 8509

Greyhound Bus Station

E Magnolia Ave 100

Transit Center

E Church Ave 301

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Philadelphia to Knoxville, TN? Compare all modes of transports from Philadelphia to Knoxville, TN.

Service and Comfort on the bus from Philadelphia to Knoxville, TN

Want to know which seat classes are available on the buses from Philadelphia to Knoxville, TN? Or which bus companies serve the route Philadelphia to Knoxville, TN? Below you will find answers to your questions.

FAQs about the Philadelphia to Knoxville, TN bus

How much does a Philadelphia Knoxville, TN bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $74 and takes 21h 35m to reach Knoxville, TN. Compare offers to save money!

How much could I save by comparing buses from Philadelphia to Knoxville, TN?

This route is offered by 2 companies with a range of ticket prices between $74 and $109. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Knoxville, TN.

On average, how many connections are available from Philadelphia to Knoxville, TN each day?

Every day, the Philadelphia to Knoxville, TN bus route is served by approximately 4 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Philadelphia to Knoxville, TN take?

The fastest bus from Philadelphia to Knoxville, TN is offered by FlixBus and takes 16h 10m. Bus tickets for this connection cost $86. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Philadelphia to Knoxville, TN?

The earliest bus arriving in Knoxville, TN from Philadelphia starts at 1:55 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Philadelphia to Knoxville, TN?

The latest bus trip departing from Philadelphia for Knoxville, TN starts at 8:45 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Philadelphia Knoxville, TN route?

When traveling by bus from Philadelphia to Knoxville, TN, passengers can travel with FlixBus and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Philadelphia and Knoxville, TN?

You can check all the direct connections between Philadelphia and Knoxville, TN by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound US.

What can I take with me on the Philadelphia to Knoxville, TN bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Philadelphia Knoxville, TN bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Philadelphia Knoxville, TN bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Philadelphia to Knoxville, TN on your planned travel date.

Available seat classes which are offered on the bus route Philadelphia to Knoxville, TN

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Philadelphia and to Knoxville, TN

Here’s an overview of the most popular bus routes to Philadelphia and to Knoxville, TN. Simply click on the connection of your choice, and you will find all the details about your bus route!