Compare all timetables for the bus from Roanoke, VA to Knoxville, TN
Here is a selection of the cheapest bus trips from the schedule from Roanoke, VA to Knoxville, TN from various bus operators like Greyhound US for the next days.
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 5h 10m | 12:50 PM | Roanoke, VA | Greyhound | 6:00 PM | Knoxville, TN | Greyhound Bus Station | Economy | $44 |
A Bus from Greyhound US goes from Greyhound, Roanoke, VA (USA) at 12/8/2025 12:50:00 PM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 12/8/2025 6:00:00 PM. 50 Economy ticket for $44 per person are available. Travel duration is 5h 10m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 5h 10m | 12:50 PM | Roanoke, VA | Greyhound | 6:00 PM | Knoxville, TN | Greyhound Bus Station | Economy | $42 |
A Bus from Greyhound US goes from Greyhound, Roanoke, VA (USA) at 12/10/2025 12:50:00 PM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 12/10/2025 6:00:00 PM. 50 Economy ticket for $42 per person are available. Travel duration is 5h 10m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 5h 10m | 12:50 PM | Roanoke, VA | Greyhound | 6:00 PM | Knoxville, TN | Greyhound Bus Station | Economy | $45 |
A Bus from Greyhound US goes from Greyhound, Roanoke, VA (USA) at 12/11/2025 12:50:00 PM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 12/11/2025 6:00:00 PM. 50 Economy ticket for $45 per person are available. Travel duration is 5h 10m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 5h 10m | 12:50 PM | Roanoke, VA | Greyhound | 6:00 PM | Knoxville, TN | Greyhound Bus Station | Economy | $46 |
A Bus from Greyhound US goes from Greyhound, Roanoke, VA (USA) at 12/13/2025 12:50:00 PM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 12/13/2025 6:00:00 PM. 50 Economy ticket for $46 per person are available. Travel duration is 5h 10m
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Best Price Offer: The price for the cheapest bus from Roanoke, VA to Knoxville, TN is $42 on 12/10/2025. Flexible travelers save on ticket prices.
Facts about the bus from Roanoke, VA to Knoxville, TN
Compare all providers like Greyhound US that travel 1 times every day by bus from Roanoke, VA to Knoxville, TN in one click! Book your bus ticket from Roanoke, VA to Knoxville, TN starting from $42!
| Cheapest Bus | $42 |
| Fastest Bus | 5h 10m |
| Earliest Bus | 12:50 PM |
| Latest Bus | 12:50 PM |
| Daily Bus Routes | 1 Ø |
| Distance | 238.1 miles |
| Bus Companies | Greyhound US |
Cheapest bus connections from Roanoke, VA to Knoxville, TN
Every day, 1 buses from 1 bus companies leave Roanoke, VA for Knoxville, TN: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/07/2025 and for the following days.
Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday
12/07
Monday
12/08
$44
Tuesday
12/09
Wednesday
12/10
$42
Thursday
12/11
$45
Friday
12/12
Saturday
12/13
$46
Sunday
12/14
Monday
12/15
Tuesday
12/16
Wednesday
12/17
Thursday
12/18
Friday
12/19
Saturday
12/20
Sunday
12/21
Monday
12/22
Tuesday
12/23
Wednesday
12/24
Thursday
12/25
Friday
12/26
Saturday
12/27
Sunday
12/28
Monday
12/29
Tuesday
12/30
Wednesday
12/31
Thursday
01/01
Friday
01/02
Saturday
01/03
How to save money travelling from Roanoke, VA to Knoxville, TN
Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:
Book the ticket from Roanoke, VA to Knoxville, TN in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Roanoke, VA to Knoxville, TN, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Roanoke, VA to Knoxville, TN are also emptier.Beloved bus companies from Roanoke, VA to Knoxville, TN
These are the most booked bus companies between Roanoke, VA to Knoxville, TN from our users.
Greyhound US from Roanoke, VA to Knoxville, TN
Here you will find the key facts about the Greyhound US bus route Roanoke, VA to Knoxville, TN:
| Cheapest Price | $42 |
| Fastest Bus | 5h 10m |
| Earliest Bus | 12:50 PM |
| Last Bus | 12:50 PM |
| Daily Connections | 1 Ø |
| Found on | 12/5/2025 |
All bus stations and stops in Roanoke, VA and Knoxville, TN
In the map below, you can see where to find all bus stations in Roanoke, VA and Knoxville, TN.
Service and Comfort on the bus from Roanoke, VA to Knoxville, TN
Want to know which seat classes are available on the buses from Roanoke, VA to Knoxville, TN? Or which bus companies serve the route Roanoke, VA to Knoxville, TN? Below you will find answers to your questions.
FAQs about the Roanoke, VA to Knoxville, TN bus
How much does a Roanoke, VA Knoxville, TN bus trip cost?
This depends on, among other things, the day and time of travel. The cheapest trip is available from $42 and takes 5h 10m to reach Knoxville, TN. Compare offers to save money!
How much could I save by comparing buses from Roanoke, VA to Knoxville, TN?
This route is offered by 1 companies with a range of ticket prices between $42 and $46. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Knoxville, TN.
On average, how many connections are available from Roanoke, VA to Knoxville, TN each day?
Every day, the Roanoke, VA to Knoxville, TN bus route is served by approximately 1 connections. With our search, you can compare bus times to find the perfect trip.
How long does a bus journey from Roanoke, VA to Knoxville, TN take?
The fastest bus from Roanoke, VA to Knoxville, TN is offered by Greyhound US and takes 5h 10m. Bus tickets for this connection cost $44. In this context, bear in mind that the journey can take longer due to traffic.
What time is the first bus from Roanoke, VA to Knoxville, TN?
The earliest bus arriving in Knoxville, TN from Roanoke, VA starts at 12:50 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.
What time is the last bus from Roanoke, VA to Knoxville, TN?
The latest bus trip departing from Roanoke, VA for Knoxville, TN starts at 12:50 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.
Which bus companies operate the Roanoke, VA Knoxville, TN route?
When traveling by bus from Roanoke, VA to Knoxville, TN, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.
Is there a direct bus between Roanoke, VA and Knoxville, TN?
You can check all the direct connections between Roanoke, VA and Knoxville, TN by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.
What can I take with me on the Roanoke, VA to Knoxville, TN bus route?
Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Roanoke, VA Knoxville, TN bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.
What equipment is available for the Roanoke, VA Knoxville, TN bus route?
The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Roanoke, VA to Knoxville, TN on your planned travel date.
Available seat classes which are offered on the bus route Roanoke, VA to Knoxville, TN
Economy
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
More bus routes to Roanoke, VA and to Knoxville, TN
Here’s an overview of the most popular bus routes to Roanoke, VA and to Knoxville, TN. Simply click on the connection of your choice, and you will find all the details about your bus route!
- Bus Routes to Roanoke, VA
- Bus to Roanoke, VA from Atlanta, GA
- Bus to Roanoke, VA from Baltimore, MD
- Columbus, OH to Roanoke, VA bus
- Denver to Roanoke, VA bus
- Buses to Roanoke, VA from Fayetteville, NC
- Buses Lubbock, TX to Roanoke, VA
- Lynchburg, VA to Roanoke, VA bus
- Buses Nashville to Roanoke, VA
- Buses Newark - Roanoke, VA
- Buses from Norfolk, VA to Roanoke, VA
- Buses to Roanoke, VA from Richmond, VA
- Buses to Roanoke, VA from Rockford, IL
- Buses Seattle, WA to Roanoke, VA
- Buses Tysons, VA - Roanoke, VA
- Buses from Virginia Beach to Roanoke, VA
- Bus Washington, DC to Roanoke, VA
- Bus Worcester, MA to Roanoke, VA
- Bus Routes to Knoxville, TN
- Bus Carbondale, IL to Knoxville, TN
- Chicago to Knoxville, TN bus
- Bus Cincinnati to Knoxville, TN
- Bus Detroit to Knoxville, TN
- Bus to Knoxville, TN from Fort Lauderdale, FL
- Buses from Greensboro, NC to Knoxville, TN
- Buses Indianapolis - Knoxville, TN
- Bus from Lexington, KY to Knoxville, TN
- Buses to Knoxville, TN from Los Angeles
- Bus from Macon, GA to Knoxville, TN
- Bus to Knoxville, TN from Midland, TX
- Bus to Knoxville, TN from Mobile, AL
- Bus from Murfreesboro, TN to Knoxville, TN
- Bus Newark - Knoxville, TN
- Orlando, FL to Knoxville, TN bus
- Bus to Knoxville, TN from Philadelphia
- Buses from Silver Spring, MD to Knoxville, TN
- Bus Tampa - Knoxville, TN
- Buses Tifton, GA - Knoxville, TN
- From Toronto, ON to Knoxville, TN bus
Popular Airport Shuttles to Roanoke, VA and to Knoxville, TN
