Bus from San Antonio, TX to Knoxville, TN from $112

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Compare all timetables for the bus from San Antonio, TX to Knoxville, TN

Here is a selection of the cheapest bus trips from the schedule from San Antonio, TX to Knoxville, TN from various bus operators like FlixBus, Greyhound US or Valley Transit for the next days.

today
$129
tomorrow
$137
Sunday
$130
Monday
Tuesday
$122
Wednesday
$129
Thursday
$128

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 23h 45m 9:55 PM San Antonio, TX Bus Station 10:40 PM Knoxville, TN Greyhound Bus Station  Economy $129
Greyhound US 31h 20m 1:30 PM San Antonio, TX Bus Station 9:50 PM Knoxville, TN Greyhound Bus Station  Economy $129
FlixBus 37h 5m 7:45 AM San Antonio, TX Pearl District 9:50 PM Knoxville, TN Greyhound Bus Station  Economy $130

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 31h 20m 1:30 PM San Antonio, TX Bus Station 9:50 PM Knoxville, TN Knoxville Area Transit Bus Stop  Economy $137
FlixBus 37h 5m 7:45 AM San Antonio, TX Pearl District 9:50 PM Knoxville, TN Knoxville Area Transit Bus Stop  Economy $138
FlixBus 23h 45m 9:55 PM San Antonio, TX Bus Station 10:40 PM Knoxville, TN Knoxville Area Transit Bus Stop  Economy $139

Cheapest bus trips Sunday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 31h 20m 1:30 PM San Antonio, TX Bus Station 9:50 PM Knoxville, TN Knoxville Area Transit Bus Stop  Economy $130
FlixBus 23h 45m 9:55 PM San Antonio, TX Bus Station 10:40 PM Knoxville, TN Knoxville Area Transit Bus Stop  Economy $132
FlixBus 37h 5m 7:45 AM San Antonio, TX Pearl District 9:50 PM Knoxville, TN Knoxville Area Transit Bus Stop  Economy $133

Cheapest bus trips Tuesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 31h 20m 1:30 PM San Antonio, TX Bus Station 9:50 PM Knoxville, TN Knoxville Area Transit Bus Stop  Economy $122
FlixBus 23h 45m 9:55 PM San Antonio, TX Bus Station 10:40 PM Knoxville, TN Knoxville Area Transit Bus Stop  Economy $124

Cheapest bus trips Wednesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 24h 40m 9:00 PM San Antonio, TX Bus Station 10:40 PM Knoxville, TN Greyhound Bus Station  Economy $129
Greyhound US 31h 20m 1:30 PM San Antonio, TX Bus Station 9:50 PM Knoxville, TN Greyhound Bus Station  Economy $137

Cheapest bus trips Thursday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 37h 5m 7:45 AM San Antonio, TX Pearl District 9:50 PM Knoxville, TN Knoxville Area Transit Bus Stop  Economy $128
Greyhound US 31h 20m 1:30 PM San Antonio, TX Bus Station 9:50 PM Knoxville, TN Knoxville Area Transit Bus Stop  Economy $129
Valley Transit 24h 40m 9:00 PM San Antonio, TX Bus Station 10:40 PM Knoxville, TN Knoxville Area Transit Bus Stop  Economy $133

Best Price Offer: The price for the cheapest bus from San Antonio, TX to Knoxville, TN is $112 on 6/7/2026. Flexible travelers save on ticket prices.


Frequency of bus connections between San Antonio, TX and Knoxville, TN

See here how frequent the connections between San Antonio, TX and Knoxville, TN are, during different times and days of the week.
Sunday is the busiest day, with more than 6 daily buses from San Antonio, TX to Knoxville, TN. Tuesday has instead the fewest connections, with only 2 daily coaches between San Antonio, TX and Knoxville, TN.
The busiest time of the day is the Afternoon, with 8 buses from San Antonio, TX to Knoxville, TN, while Morning sees the fewest connections between San Antonio, TX and Knoxville, TN, with 6 offers.

Facts about the bus from San Antonio, TX to Knoxville, TN

Compare all providers like FlixBus, Greyhound US and Valley Transit that travel 3 times every day by bus from San Antonio, TX to Knoxville, TN in one click! Book your bus ticket from San Antonio, TX to Knoxville, TN starting from $112!

Cheapest Bus $112
Fastest Bus 24h 45m
Earliest Bus 7:45 AM
Latest Bus 9:00 PM
Daily Bus Routes 3 Ø
Distance 958.9 miles
Bus Companies FlixBus, Greyhound US and Valley Transit

Cheapest bus connections from San Antonio, TX to Knoxville, TN

Every day, 3 buses from 3 bus companies leave San Antonio, TX for Knoxville, TN: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 06/12/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 06/07
Monday 06/08
Tuesday 06/09
Wednesday 06/10
Thursday 06/11
Friday 06/12
$129
Saturday 06/13
$141
Sunday 06/14
$130
Monday 06/15
Tuesday 06/16
$122
Wednesday 06/17
$129
Thursday 06/18
$128
Friday 06/19
$117
Saturday 06/20
Sunday 06/21
$120
Monday 06/22
$125
Tuesday 06/23
$134
Wednesday 06/24
$118
Thursday 06/25
Friday 06/26
$119
Saturday 06/27
$128
Sunday 06/28
$118
Monday 06/29
Tuesday 06/30
Wednesday 07/01
Thursday 07/02
$114
Friday 07/03
Saturday 07/04

The cheapest time to travel from San Antonio, TX to Knoxville, TN

See here on which day and which time of the day you can find the cheapest bus ticket from San Antonio, TX to Knoxville, TN, for the next 30 days.
With a price starting from $114, Thursday is the cheapest day for a bus from San Antonio, TX to Knoxville, TN. Saturday instead is the most expensive day with prices starting from $128.
Afternoon is the cheapest day time for bus tickets from San Antonio, TX to Knoxville, TN, with $122. Morning is the most expensive time of the day with prices starting from $128.

How to save money travelling from San Antonio, TX to Knoxville, TN

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from San Antonio, TX to Knoxville, TN in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from San Antonio, TX to Knoxville, TN, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from San Antonio, TX to Knoxville, TN are also emptier.

Beloved bus companies from San Antonio, TX to Knoxville, TN

These are the most booked bus companies between San Antonio, TX to Knoxville, TN from our users.

FlixBus from San Antonio, TX to Knoxville, TN

FlixBus

Here you will find the key facts about the FlixBus bus route San Antonio, TX to Knoxville, TN:

Cheapest Price $124
Fastest Bus 24h 45m
Earliest Bus 7:45 AM
Last Bus 7:45 AM
Daily Connections 2 Ø
Found on 5/19/2026

All bus stations and stops in San Antonio, TX and Knoxville, TN

In the map below, you can see where to find all bus stations in San Antonio, TX and Knoxville, TN.

Service and Comfort on the bus from San Antonio, TX to Knoxville, TN

Want to know which seat classes are available on the buses from San Antonio, TX to Knoxville, TN? Or which bus companies serve the route San Antonio, TX to Knoxville, TN? Below you will find answers to your questions.

FAQs about the San Antonio, TX to Knoxville, TN bus

How much does a San Antonio, TX Knoxville, TN bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $112 and takes 32h 20m to reach Knoxville, TN. Compare offers to save money!

How much could I save by comparing buses from San Antonio, TX to Knoxville, TN?

This route is offered by 3 companies with a range of ticket prices between $112 and $143. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Knoxville, TN.

On average, how many connections are available from San Antonio, TX to Knoxville, TN each day?

Every day, the San Antonio, TX to Knoxville, TN bus route is served by approximately 3 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from San Antonio, TX to Knoxville, TN take?

The fastest bus from San Antonio, TX to Knoxville, TN is offered by FlixBus and takes 24h 45m. Bus tickets for this connection cost $129. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from San Antonio, TX to Knoxville, TN?

The earliest bus arriving in Knoxville, TN from San Antonio, TX starts at 7:45 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from San Antonio, TX to Knoxville, TN?

The latest bus trip departing from San Antonio, TX for Knoxville, TN starts at 9:00 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the San Antonio, TX Knoxville, TN route?

When traveling by bus from San Antonio, TX to Knoxville, TN, passengers can travel with FlixBus, Greyhound US and Valley Transit. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between San Antonio, TX and Knoxville, TN?

You can check all the direct connections between San Antonio, TX and Knoxville, TN by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus, Greyhound US and Valley Transit.

What can I take with me on the San Antonio, TX to Knoxville, TN bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the San Antonio, TX Knoxville, TN bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the San Antonio, TX Knoxville, TN bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from San Antonio, TX to Knoxville, TN on your planned travel date.

How does CheckMyBus find the best bus deals from San Antonio, TX to Knoxville, TN?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 3 daily trips between San Antonio, TX and Knoxville, TN. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from San Antonio, TX to Knoxville, TN?

Prices and availability for 3 trips between San Antonio, TX and Knoxville, TN change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route San Antonio, TX to Knoxville, TN

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to San Antonio, TX and to Knoxville, TN

Here’s an overview of the most popular bus routes to San Antonio, TX and to Knoxville, TN. Simply click on the connection of your choice, and you will find all the details about your bus route!
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CheckMyBus › Buses in USA › Bus to San Antonio, TX › Bus to Knoxville, TN

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