Bus from Tampa to Knoxville, TN from $140

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Compare all timetables for the bus from Tampa to Knoxville, TN

Here is a selection of the cheapest bus trips from the schedule from Tampa to Knoxville, TN from various bus operators like FlixBus for the next days.
today
from $140
tomorrow
Friday
Saturday
Sunday
Monday
from $158
Tuesday
from $181

Cheapest bus trips today

Prices are for one way and one person
  • FlixBus
    24h 25m
    0
    9:25 PM
    Tampa
    Marion Street
    9:50 PM
    Knoxville, TN
    Greyhound Bus Station
    0
    FlixBus
    Economy
    $140
  • FlixBus
    24h 0m
    0
    9:50 PM
    Tampa
    USF
    9:50 PM
    Knoxville, TN
    Greyhound Bus Station
    0
    FlixBus
    Economy
    $140
  • Did you know that if you travel from Tampa to Knoxville, TN via Atlanta, GA, you can save more than $42? You can find the corresponding connections below.
    • Busbud
      28h 10m
      0
      5:40 PM
      Tampa
      USF
      7:40 AM
      Atlanta, GA
      Civic Center MARTA Station
      0
      Busbud
      Economy
      $66
      • Waiting Time 10h 25m
    • FlixBus
      3h 45m
      0
      6:05 PM
      Atlanta, GA
      Garnett Transit Station
      9:50 PM
      Knoxville, TN
      Greyhound Bus Station
      0
      FlixBus
      Economy
      $33
    Travel time is 4h 10m longer, but you will save $42

Cheapest bus trips Monday

Prices are for one way and one person
  • FlixBus
    24h 0m
    0
    9:50 PM
    Tampa
    USF
    9:50 PM
    Knoxville, TN
    Greyhound Bus Station
    0
    FlixBus
    Economy
    $158
  • FlixBus
    24h 25m
    0
    9:25 PM
    Tampa
    Marion Street
    9:50 PM
    Knoxville, TN
    Greyhound Bus Station
    0
    FlixBus
    Economy
    $159
  • Did you know that if you travel from Tampa to Knoxville, TN via Atlanta, GA, you can save more than $73? You can find the corresponding connections below.
    • Busbud
      28h 10m
      0
      5:40 PM
      Tampa
      USF
      7:40 AM
      Atlanta, GA
      Civic Center MARTA Station
      0
      Busbud
      Economy
      $48
      • Waiting Time 10h 25m
    • FlixBus
      3h 45m
      0
      6:05 PM
      Atlanta, GA
      Garnett Transit Station
      9:50 PM
      Knoxville, TN
      Greyhound Bus Station
      0
      FlixBus
      Economy
      $37
    Travel time is 4h 10m longer, but you will save $73

Cheapest bus trips Tuesday

Prices are for one way and one person
  • FlixBus
    29h 0m
    0
    5:40 PM
    Tampa
    USF
    10:40 PM
    Knoxville, TN
    Greyhound Bus Station
    0
    FlixBus
    Economy
    $181
  • FlixBus
    29h 30m
    0
    5:10 PM
    Tampa
    Marion Street
    10:40 PM
    Knoxville, TN
    Greyhound Bus Station
    0
    FlixBus
    Economy
    $182
  • FlixBus
    30h 35m
    0
    3:15 PM
    Tampa
    Marion Street
    9:50 PM
    Knoxville, TN
    Greyhound Bus Station
    0
    FlixBus
    Economy
    $199
  • FlixBus
    31h 10m
    0
    2:40 PM
    Tampa
    USF
    9:50 PM
    Knoxville, TN
    Greyhound Bus Station
    0
    FlixBus
    Economy
    $200
  • Did you know that if you travel from Tampa to Knoxville, TN via Atlanta, GA, you can save more than $96? You can find the corresponding connections below.
    • Busbud
      28h 10m
      0
      5:40 PM
      Tampa
      USF
      7:40 AM
      Atlanta, GA
      Civic Center MARTA Station
      0
      Busbud
      Economy
      $48
      • Waiting Time 10h 25m
    • FlixBus
      3h 45m
      0
      6:05 PM
      Atlanta, GA
      Garnett Transit Station
      9:50 PM
      Knoxville, TN
      Greyhound Bus Station
      0
      FlixBus
      Economy
      $37
    Travel Time is 0h 50m shorter, and you will save $96

Frequency of bus connections between Tampa and Knoxville, TN

See here how frequent the connections between Tampa and Knoxville, TN are, during different times and days of the week.
Tuesday is the busiest day, with more than 4 daily buses from Tampa to Knoxville, TN. Monday has instead the fewest connections, with only 2 daily coaches between Tampa and Knoxville, TN.
The busiest time of the day is the Afternoon, with 4 buses from Tampa to Knoxville, TN, while Afternoon sees the fewest connections between Tampa and Knoxville, TN, with 4 offers.

Facts about the bus from Tampa to Knoxville, TN

Compare all providers like FlixBus that travel 2 times every day by bus from Tampa to Knoxville, TN in one click! Book your bus ticket from Tampa to Knoxville, TN starting from $140!

Cheapest Bus $140
Fastest Bus 24h 0m
Earliest Bus 9:25 PM
Latest Bus 5:40 PM
Daily Bus Routes 2 Ø
Distance 560.1 miles
Bus Companies FlixBus

Cheapest bus connections from Tampa to Knoxville, TN

Every day, 2 buses from 1 bus companies leave Tampa for Knoxville, TN: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 06/18/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 06/15
Monday 06/16
Tuesday 06/17
Wednesday 06/18
$140
Thursday 06/19
Friday 06/20
Saturday 06/21
Sunday 06/22
Monday 06/23
$158
Tuesday 06/24
$181
Wednesday 06/25
Thursday 06/26
Friday 06/27
Saturday 06/28
Sunday 06/29
Monday 06/30
Tuesday 07/01
Wednesday 07/02
Thursday 07/03
Friday 07/04
Saturday 07/05
Sunday 07/06
Monday 07/07
Tuesday 07/08
Wednesday 07/09
Thursday 07/10
Friday 07/11
Saturday 07/12

The cheapest time to travel from Tampa to Knoxville, TN

See here on which day and which time of the day you can find the cheapest bus ticket from Tampa to Knoxville, TN, for the next 30 days.
With a price starting from $140, Wednesday is the cheapest day for a bus from Tampa to Knoxville, TN. Tuesday instead is the most expensive day with prices starting from $181.
Evening is the cheapest day time for bus tickets from Tampa to Knoxville, TN, with $140. Afternoon is the most expensive time of the day with prices starting from $181.

How to save money travelling from Tampa to Knoxville, TN

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Tampa to Knoxville, TN in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Tampa to Knoxville, TN, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Tampa to Knoxville, TN are also emptier.

All bus stations and stops in Tampa and Knoxville, TN

In the map below, you can see where to find all bus stations in Tampa and Knoxville, TN.

Service and Comfort on the bus from Tampa to Knoxville, TN

Want to know which seat classes are available on the buses from Tampa to Knoxville, TN? Or which bus companies serve the route Tampa to Knoxville, TN? Below you will find answers to your questions.

FAQs about the Tampa to Knoxville, TN bus

How much does a Tampa Knoxville, TN bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $140 and takes 24h 25m to reach Knoxville, TN. Compare offers to save money!

How much could I save by comparing buses from Tampa to Knoxville, TN?

This route is offered by 1 companies with a range of ticket prices between $140 and $200. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Knoxville, TN.

On average, how many connections are available from Tampa to Knoxville, TN each day?

Every day, the Tampa to Knoxville, TN bus route is served by approximately 2 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Tampa to Knoxville, TN take?

The fastest bus from Tampa to Knoxville, TN is offered by FlixBus and takes 24h 0m. Bus tickets for this connection cost $140. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Tampa to Knoxville, TN?

The earliest bus arriving in Knoxville, TN from Tampa starts at 9:25 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Tampa to Knoxville, TN?

The latest bus trip departing from Tampa for Knoxville, TN starts at 5:40 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Tampa Knoxville, TN route?

When traveling by bus from Tampa to Knoxville, TN, passengers can travel with FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Tampa and Knoxville, TN?

You can check all the direct connections between Tampa and Knoxville, TN by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus.

What can I take with me on the Tampa to Knoxville, TN bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Tampa Knoxville, TN bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Tampa Knoxville, TN bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Tampa to Knoxville, TN on your planned travel date.

Available seat classes which are offered on the bus route Tampa to Knoxville, TN

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Tampa and to Knoxville, TN

Here’s an overview of the most popular bus routes to Tampa and to Knoxville, TN. Simply click on the connection of your choice, and you will find all the details about your bus route!
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