Bus from Tampa to Knoxville, TN from $132

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Compare all timetables for the bus from Tampa to Knoxville, TN

Here is a selection of the cheapest bus trips from the schedule from Tampa to Knoxville, TN from various bus operators like FlixBus for the next days.

today
$132
tomorrow
Friday
Saturday
Sunday
$132
Monday
$132
Tuesday

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 24h 0m 9:50 PM Tampa USF 9:50 PM Knoxville, TN Greyhound Bus Station  Economy $132
FlixBus 23h 15m 10:35 PM Tampa Marion Street 9:50 PM Knoxville, TN Greyhound Bus Station  Economy $132
  • Did you know that if you travel from Tampa to Knoxville, TN via Atlanta, GA, you can save more than $20? You can find the corresponding connections below.
    • Busbud
      23h 15m
      0
      10:35 PM
      Tampa
      Marion Street
      3:25 PM
      Atlanta, GA
      Garnett Transit Station
      0
      Busbud
      Economy
      $66
      • Waiting Time 2h 40m
    • FlixBus
      3h 45m
      0
      6:05 PM
      Atlanta, GA
      Garnett Transit Station
      9:50 PM
      Knoxville, TN
      Greyhound Bus Station
      0
      FlixBus
      Economy
      $46
    Travel time is the same as the direct connection, but you will save $20

Cheapest bus trips Sunday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 24h 0m 9:50 PM Tampa USF 9:50 PM Knoxville, TN Greyhound Bus Station  Economy $132
FlixBus 23h 15m 10:35 PM Tampa Marion Street 9:50 PM Knoxville, TN Greyhound Bus Station  Economy $132
  • Did you know that if you travel from Tampa to Knoxville, TN via Atlanta, GA, you can save more than $20? You can find the corresponding connections below.
    • Busbud
      23h 15m
      0
      10:35 PM
      Tampa
      Marion Street
      3:25 PM
      Atlanta, GA
      Garnett Transit Station
      0
      Busbud
      Economy
      $66
      • Waiting Time 2h 40m
    • FlixBus
      3h 45m
      0
      6:05 PM
      Atlanta, GA
      Garnett Transit Station
      9:50 PM
      Knoxville, TN
      Greyhound Bus Station
      0
      FlixBus
      Economy
      $46
    Travel time is the same as the direct connection, but you will save $20

Cheapest bus trips Monday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 24h 0m 9:50 PM Tampa USF 9:50 PM Knoxville, TN Greyhound Bus Station  Economy $132
FlixBus 23h 15m 10:35 PM Tampa Marion Street 9:50 PM Knoxville, TN Greyhound Bus Station  Economy $132
  • Did you know that if you travel from Tampa to Knoxville, TN via Atlanta, GA, you can save more than $20? You can find the corresponding connections below.
    • Busbud
      23h 15m
      0
      10:35 PM
      Tampa
      Marion Street
      3:25 PM
      Atlanta, GA
      Garnett Transit Station
      0
      Busbud
      Economy
      $66
      • Waiting Time 2h 40m
    • FlixBus
      3h 45m
      0
      6:05 PM
      Atlanta, GA
      Garnett Transit Station
      9:50 PM
      Knoxville, TN
      Greyhound Bus Station
      0
      FlixBus
      Economy
      $46
    Travel time is the same as the direct connection, but you will save $20

Best Price Offer: The price for the cheapest bus from Tampa to Knoxville, TN is $132 on 12/24/2025. Flexible travelers save on ticket prices.


Facts about the bus from Tampa to Knoxville, TN

Compare all providers like FlixBus that travel 2 times every day by bus from Tampa to Knoxville, TN in one click! Book your bus ticket from Tampa to Knoxville, TN starting from $132!

Cheapest Bus $132
Fastest Bus 23h 15m
Earliest Bus 9:50 PM
Latest Bus 10:35 PM
Daily Bus Routes 2 Ø
Distance 560.1 miles
Bus Companies FlixBus

Cheapest bus connections from Tampa to Knoxville, TN

Every day, 2 buses from 1 bus companies leave Tampa for Knoxville, TN: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/24/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 12/21
Monday 12/22
Tuesday 12/23
Wednesday 12/24
$132
Thursday 12/25
Friday 12/26
Saturday 12/27
Sunday 12/28
$132
Monday 12/29
$132
Tuesday 12/30
Wednesday 12/31
Thursday 01/01
Friday 01/02
Saturday 01/03
Sunday 01/04
Monday 01/05
Tuesday 01/06
Wednesday 01/07
Thursday 01/08
Friday 01/09
Saturday 01/10
Sunday 01/11
Monday 01/12
Tuesday 01/13
Wednesday 01/14
Thursday 01/15
Friday 01/16
Saturday 01/17

How to save money travelling from Tampa to Knoxville, TN

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Tampa to Knoxville, TN in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Tampa to Knoxville, TN, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Tampa to Knoxville, TN are also emptier.

All bus stations and stops in Tampa and Knoxville, TN

In the map below, you can see where to find all bus stations in Tampa and Knoxville, TN.

Service and Comfort on the bus from Tampa to Knoxville, TN

Want to know which seat classes are available on the buses from Tampa to Knoxville, TN? Or which bus companies serve the route Tampa to Knoxville, TN? Below you will find answers to your questions.

FAQs about the Tampa to Knoxville, TN bus

How much does a Tampa Knoxville, TN bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $132 and takes 24h 0m to reach Knoxville, TN. Compare offers to save money!

How much could I save by comparing buses from Tampa to Knoxville, TN?

This route is offered by 1 companies with a range of ticket prices between $132 and $132. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Knoxville, TN.

On average, how many connections are available from Tampa to Knoxville, TN each day?

Every day, the Tampa to Knoxville, TN bus route is served by approximately 2 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Tampa to Knoxville, TN take?

The fastest bus from Tampa to Knoxville, TN is offered by FlixBus and takes 23h 15m. Bus tickets for this connection cost $132. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Tampa to Knoxville, TN?

The earliest bus arriving in Knoxville, TN from Tampa starts at 9:50 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Tampa to Knoxville, TN?

The latest bus trip departing from Tampa for Knoxville, TN starts at 10:35 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Tampa Knoxville, TN route?

When traveling by bus from Tampa to Knoxville, TN, passengers can travel with FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Tampa and Knoxville, TN?

You can check all the direct connections between Tampa and Knoxville, TN by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus.

What can I take with me on the Tampa to Knoxville, TN bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Tampa Knoxville, TN bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Tampa Knoxville, TN bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Tampa to Knoxville, TN on your planned travel date.

How does CheckMyBus find the best bus deals from Tampa to Knoxville, TN?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 2 daily trips between Tampa and Knoxville, TN. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Tampa to Knoxville, TN?

Prices and availability for 2 trips between Tampa and Knoxville, TN change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Tampa to Knoxville, TN

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Tampa and to Knoxville, TN

Here’s an overview of the most popular bus routes to Tampa and to Knoxville, TN. Simply click on the connection of your choice, and you will find all the details about your bus route!
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