Bus Mobile, AL to Knoxville, TN: Compare prices and save money

Compare all timetables for the bus from Mobile, AL to Knoxville, TN

Here is a selection of the cheapest bus trips from the schedule from Mobile, AL to Knoxville, TN from various bus operators like Greyhound US for the next days.

today

tomorrow

$108

Saturday

Sunday

$111

Monday

$100

Tuesday

Wednesday

Cheapest bus trips tomorrow
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	13h 20m	7:30 AM	Mobile, AL	Greyhound Bus Station	9:50 PM	Knoxville, TN	Greyhound Bus Station		Economy	$108	A Bus from Greyhound US goes from Greyhound Bus Station, Mobile, AL (USA) at 12/5/2025 7:30:00 AM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 12/5/2025 9:50:00 PM. 50 Economy ticket for $108 per person are available. Travel duration is 13h 20m

Did you know that if you travel from Mobile, AL to Knoxville, TN via Atlanta, GA, you can save more than $26? You can find the corresponding connections below.
- Busbud
  
  20h 45m
  
  0
  
  12:05 AM
  
  Mobile, AL
  Greyhound Bus Station
  
  7:25 AM
  
  Atlanta, GA
  Garnett Transit Station
  
  0
  
  Economy
  
  $46
  
  A Bus from Busbud goes from Greyhound Bus Station, Mobile, AL (USA) at 12/5/2025 12:05:00 AM to Garnett Transit Station, Atlanta, GA (USA) arriving at 12/5/2025 7:25:00 AM. 50 Economy ticket for $46 per person are available. Travel duration is 6h 20m
- FlixBus
  
  3h 45m
  
  0
  
  6:05 PM
  
  Atlanta, GA
  Garnett Transit Station
  
  9:50 PM
  
  Knoxville, TN
  Greyhound Bus Station
  
  0
  
  Economy
  
  $36
  
  A Bus from FlixBus goes from Garnett Transit Station, Atlanta, GA (USA) at 12/5/2025 6:05:00 PM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 12/5/2025 9:50:00 PM. 50 Economy ticket for $36 per person are available. Travel duration is 3h 45m
Travel time is 6h 25m longer, but you will save $26

Cheapest bus trips Sunday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	13h 20m	7:30 AM	Mobile, AL	Greyhound Bus Station	9:50 PM	Knoxville, TN	Knoxville Area Transit Bus Stop		Economy	$111	A Bus from Greyhound US goes from Greyhound Bus Station, Mobile, AL (USA) at 12/7/2025 7:30:00 AM to Knoxville Area Transit Bus Stop, Knoxville, TN (USA) arriving at 12/7/2025 9:50:00 PM. 50 Economy ticket for $111 per person are available. Travel duration is 13h 20m

Did you know that if you travel from Mobile, AL to Knoxville, TN via Atlanta, GA, you can save more than $29? You can find the corresponding connections below.
- Busbud
  
  20h 45m
  
  0
  
  12:05 AM
  
  Mobile, AL
  Greyhound Bus Station
  
  7:25 AM
  
  Atlanta, GA
  Garnett Transit Station
  
  0
  
  Economy
  
  $46
  
  A Bus from Busbud goes from Greyhound Bus Station, Mobile, AL (USA) at 12/5/2025 12:05:00 AM to Garnett Transit Station, Atlanta, GA (USA) arriving at 12/5/2025 7:25:00 AM. 50 Economy ticket for $46 per person are available. Travel duration is 6h 20m
- FlixBus
  
  3h 45m
  
  0
  
  6:05 PM
  
  Atlanta, GA
  Garnett Transit Station
  
  9:50 PM
  
  Knoxville, TN
  Greyhound Bus Station
  
  0
  
  Economy
  
  $36
  
  A Bus from FlixBus goes from Garnett Transit Station, Atlanta, GA (USA) at 12/5/2025 6:05:00 PM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 12/5/2025 9:50:00 PM. 50 Economy ticket for $36 per person are available. Travel duration is 3h 45m
Travel time is 6h 25m longer, but you will save $29

Cheapest bus trips Monday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	13h 20m	7:30 AM	Mobile, AL	Greyhound Bus Station	9:50 PM	Knoxville, TN	Knoxville Area Transit Bus Stop		Economy	$100	A Bus from Greyhound US goes from Greyhound Bus Station, Mobile, AL (USA) at 12/8/2025 7:30:00 AM to Knoxville Area Transit Bus Stop, Knoxville, TN (USA) arriving at 12/8/2025 9:50:00 PM. 50 Economy ticket for $100 per person are available. Travel duration is 13h 20m

Did you know that if you travel from Mobile, AL to Knoxville, TN via Atlanta, GA, you can save more than $18? You can find the corresponding connections below.
- Busbud
  
  20h 45m
  
  0
  
  12:05 AM
  
  Mobile, AL
  Greyhound Bus Station
  
  7:25 AM
  
  Atlanta, GA
  Garnett Transit Station
  
  0
  
  Economy
  
  $46
  
  A Bus from Busbud goes from Greyhound Bus Station, Mobile, AL (USA) at 12/5/2025 12:05:00 AM to Garnett Transit Station, Atlanta, GA (USA) arriving at 12/5/2025 7:25:00 AM. 50 Economy ticket for $46 per person are available. Travel duration is 6h 20m
- FlixBus
  
  3h 45m
  
  0
  
  6:05 PM
  
  Atlanta, GA
  Garnett Transit Station
  
  9:50 PM
  
  Knoxville, TN
  Greyhound Bus Station
  
  0
  
  Economy
  
  $36
  
  A Bus from FlixBus goes from Garnett Transit Station, Atlanta, GA (USA) at 12/5/2025 6:05:00 PM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 12/5/2025 9:50:00 PM. 50 Economy ticket for $36 per person are available. Travel duration is 3h 45m
Travel time is 6h 25m longer, but you will save $18

Best Price Offer: The price for the cheapest bus from Mobile, AL to Knoxville, TN is $100 on 12/8/2025. Flexible travelers save on ticket prices.

Facts about the bus from Mobile, AL to Knoxville, TN

Compare all providers like Greyhound US that travel 1 times every day by bus from Mobile, AL to Knoxville, TN in one click! Book your bus ticket from Mobile, AL to Knoxville, TN starting from $100!

Cheapest Bus	$100
Fastest Bus	14h 20m
Earliest Bus	7:30 AM
Latest Bus	7:30 AM
Daily Bus Routes	1 Ø
Distance	435.0 miles
Bus Companies	Greyhound US

Cheapest bus connections from Mobile, AL to Knoxville, TN

Every day, 1 buses from 1 bus companies leave Mobile, AL for Knoxville, TN: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/04/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 11/30

Monday 12/01

Tuesday 12/02

Wednesday 12/03

Thursday 12/04

Friday 12/05

$108

Saturday 12/06

Sunday 12/07

$111

Monday 12/08

$100

Tuesday 12/09

Wednesday 12/10

Thursday 12/11

Friday 12/12

Saturday 12/13

Sunday 12/14

Monday 12/15

Tuesday 12/16

Wednesday 12/17

Thursday 12/18

Friday 12/19

Saturday 12/20

Sunday 12/21

Monday 12/22

Tuesday 12/23

Wednesday 12/24

Thursday 12/25

Friday 12/26

Saturday 12/27

How to save money travelling from Mobile, AL to Knoxville, TN

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Mobile, AL to Knoxville, TN in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Mobile, AL to Knoxville, TN, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Mobile, AL to Knoxville, TN are also emptier.

All bus stations and stops in Mobile, AL and Knoxville, TN

In the map below, you can see where to find all bus stations in Mobile, AL and Knoxville, TN.

Greyhound Bus Station

Government Blvd 1545

GM&O Transit Center

Beauregard St 110

I-65 Hwy Exit 4 McDonald's

Springdale Blvd 2

Kingston Pike

Kingston Pike 6927

Knoxville Area Transit Bus Stop

Knoxville Area Transit Bus Stop Knoxville Area Transit Bus Stop

Walker Springs Plaza Shopping Center

Kingston Pike 8509

Greyhound Bus Station

E Magnolia Ave 100

Transit Center

E Church Ave 301

Service and Comfort on the bus from Mobile, AL to Knoxville, TN

Want to know which seat classes are available on the buses from Mobile, AL to Knoxville, TN? Or which bus companies serve the route Mobile, AL to Knoxville, TN? Below you will find answers to your questions.

FAQs about the Mobile, AL to Knoxville, TN bus

How much does a Mobile, AL Knoxville, TN bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $100 and takes 14h 20m to reach Knoxville, TN. Compare offers to save money!

How much could I save by comparing buses from Mobile, AL to Knoxville, TN?

This route is offered by 1 companies with a range of ticket prices between $100 and $111. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Knoxville, TN.

On average, how many connections are available from Mobile, AL to Knoxville, TN each day?

Every day, the Mobile, AL to Knoxville, TN bus route is served by approximately 1 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Mobile, AL to Knoxville, TN take?

The fastest bus from Mobile, AL to Knoxville, TN is offered by Greyhound US and takes 14h 20m. Bus tickets for this connection cost $108. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Mobile, AL to Knoxville, TN?

The earliest bus arriving in Knoxville, TN from Mobile, AL starts at 7:30 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Mobile, AL to Knoxville, TN?

The latest bus trip departing from Mobile, AL for Knoxville, TN starts at 7:30 AM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Mobile, AL Knoxville, TN route?

When traveling by bus from Mobile, AL to Knoxville, TN, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Mobile, AL and Knoxville, TN?

You can check all the direct connections between Mobile, AL and Knoxville, TN by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Mobile, AL to Knoxville, TN bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Mobile, AL Knoxville, TN bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Mobile, AL Knoxville, TN bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Mobile, AL to Knoxville, TN on your planned travel date.

Available seat classes which are offered on the bus route Mobile, AL to Knoxville, TN

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Mobile, AL and to Knoxville, TN

Here’s an overview of the most popular bus routes to Mobile, AL and to Knoxville, TN. Simply click on the connection of your choice, and you will find all the details about your bus route!