Compare all timetables for the bus from Jacksonville, FL to Knoxville, TN
Here is a selection of the cheapest bus trips from the schedule from Jacksonville, FL to Knoxville, TN from various bus operators like FlixBus for the next days.
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 23h 45m | 10:05 PM | Jacksonville, FL | Amtrak Train Station | 9:50 PM | Knoxville, TN | Greyhound Bus Station | Economy | $113 |
A Bus from FlixBus goes from Amtrak Train Station, Jacksonville, FL (USA) at 12/8/2025 10:05:00 PM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 12/9/2025 9:50:00 PM. 50 Economy ticket for $113 per person are available. Travel duration is 23h 45m
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| FlixBus | 12h 45m | 9:05 AM | Jacksonville, FL | Amtrak Train Station | 9:50 PM | Knoxville, TN | Greyhound Bus Station | Economy | $116 |
A Bus from FlixBus goes from Amtrak Train Station, Jacksonville, FL (USA) at 12/8/2025 9:05:00 AM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 12/8/2025 9:50:00 PM. 50 Economy ticket for $116 per person are available. Travel duration is 12h 45m
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Did you know that if you travel from Jacksonville, FL to Knoxville, TN via Atlanta, GA, you can save more than $29? You can find the corresponding connections below.
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FlixBus13h 50m08:00 AMJacksonville, FLAmtrak Train Station3:25 PMAtlanta, GAGarnett Transit Station0EconomyA Bus from FlixBus goes from Amtrak Train Station, Jacksonville, FL (USA) at 12/10/2025 8:00:00 AM to Garnett Transit Station, Atlanta, GA (USA) arriving at 12/10/2025 3:25:00 PM. 50 Economy ticket for $50 per person are available. Travel duration is 7h 25m
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FlixBus3h 45m06:05 PMAtlanta, GAGarnett Transit Station9:50 PMKnoxville, TNGreyhound Bus Station0EconomyA Bus from FlixBus goes from Garnett Transit Station, Atlanta, GA (USA) at 12/10/2025 6:05:00 PM to Greyhound Bus Station, Knoxville, TN (USA) arriving at 12/10/2025 9:50:00 PM. 50 Economy ticket for $34 per person are available. Travel duration is 3h 45m
Waiting Time 2h 40mTravel time is 1h 5m longer, but you will save $29 -
Best Price Offer: The price for the cheapest bus from Jacksonville, FL to Knoxville, TN is $108 on 12/3/2025. Flexible travelers save on ticket prices.
Facts about the bus from Jacksonville, FL to Knoxville, TN
Compare all providers like FlixBus that travel 2 times every day by bus from Jacksonville, FL to Knoxville, TN in one click! Book your bus ticket from Jacksonville, FL to Knoxville, TN starting from $108!
| Cheapest Bus | $108 |
| Fastest Bus | 12h 45m |
| Earliest Bus | 9:05 AM |
| Latest Bus | 10:05 PM |
| Daily Bus Routes | 2 Ø |
| Distance | 410.5 miles |
| Bus Companies | FlixBus |
Cheapest bus connections from Jacksonville, FL to Knoxville, TN
Every day, 2 buses from 1 bus companies leave Jacksonville, FL for Knoxville, TN: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/04/2025 and for the following days.
Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday
11/30
Monday
12/01
Tuesday
12/02
Wednesday
12/03
Thursday
12/04
Friday
12/05
Saturday
12/06
Sunday
12/07
Monday
12/08
$113
Tuesday
12/09
Wednesday
12/10
Thursday
12/11
$120
Friday
12/12
Saturday
12/13
Sunday
12/14
Monday
12/15
Tuesday
12/16
Wednesday
12/17
Thursday
12/18
Friday
12/19
Saturday
12/20
Sunday
12/21
Monday
12/22
Tuesday
12/23
Wednesday
12/24
Thursday
12/25
Friday
12/26
Saturday
12/27
How to save money travelling from Jacksonville, FL to Knoxville, TN
Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:
Book the ticket from Jacksonville, FL to Knoxville, TN in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Jacksonville, FL to Knoxville, TN, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Jacksonville, FL to Knoxville, TN are also emptier.Beloved bus companies from Jacksonville, FL to Knoxville, TN
These are the most booked bus companies between Jacksonville, FL to Knoxville, TN from our users.
FlixBus from Jacksonville, FL to Knoxville, TN
Here you will find the key facts about the FlixBus bus route Jacksonville, FL to Knoxville, TN:
| Cheapest Price | $113 |
| Fastest Bus | 12h 45m |
| Earliest Bus | 9:05 AM |
| Last Bus | 10:05 PM |
| Daily Connections | 2 Ø |
| Found on | 11/30/2025 |
All bus stations and stops in Jacksonville, FL and Knoxville, TN
In the map below, you can see where to find all bus stations in Jacksonville, FL and Knoxville, TN.
Service and Comfort on the bus from Jacksonville, FL to Knoxville, TN
Want to know which seat classes are available on the buses from Jacksonville, FL to Knoxville, TN? Or which bus companies serve the route Jacksonville, FL to Knoxville, TN? Below you will find answers to your questions.
FAQs about the Jacksonville, FL to Knoxville, TN bus
How much does a Jacksonville, FL Knoxville, TN bus trip cost?
This depends on, among other things, the day and time of travel. The cheapest trip is available from $108 and takes 23h 45m to reach Knoxville, TN. Compare offers to save money!
How much could I save by comparing buses from Jacksonville, FL to Knoxville, TN?
This route is offered by 1 companies with a range of ticket prices between $108 and $116. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Knoxville, TN.
On average, how many connections are available from Jacksonville, FL to Knoxville, TN each day?
Every day, the Jacksonville, FL to Knoxville, TN bus route is served by approximately 2 connections. With our search, you can compare bus times to find the perfect trip.
How long does a bus journey from Jacksonville, FL to Knoxville, TN take?
The fastest bus from Jacksonville, FL to Knoxville, TN is offered by FlixBus and takes 12h 45m. Bus tickets for this connection cost $116. In this context, bear in mind that the journey can take longer due to traffic.
What time is the first bus from Jacksonville, FL to Knoxville, TN?
The earliest bus arriving in Knoxville, TN from Jacksonville, FL starts at 9:05 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.
What time is the last bus from Jacksonville, FL to Knoxville, TN?
The latest bus trip departing from Jacksonville, FL for Knoxville, TN starts at 10:05 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.
Which bus companies operate the Jacksonville, FL Knoxville, TN route?
When traveling by bus from Jacksonville, FL to Knoxville, TN, passengers can travel with FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.
Is there a direct bus between Jacksonville, FL and Knoxville, TN?
You can check all the direct connections between Jacksonville, FL and Knoxville, TN by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus.
What can I take with me on the Jacksonville, FL to Knoxville, TN bus route?
Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Jacksonville, FL Knoxville, TN bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.
What equipment is available for the Jacksonville, FL Knoxville, TN bus route?
The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Jacksonville, FL to Knoxville, TN on your planned travel date.
Available seat classes which are offered on the bus route Jacksonville, FL to Knoxville, TN
Economy
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
More bus routes to Jacksonville, FL and to Knoxville, TN
Here’s an overview of the most popular bus routes to Jacksonville, FL and to Knoxville, TN. Simply click on the connection of your choice, and you will find all the details about your bus route!
- Bus Routes to Jacksonville, FL
- Bus to Jacksonville, FL from Bridgeport, CT
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- Buses from Fort Myers, FL to Jacksonville, FL
- Buses from Fort Pierce, FL to Jacksonville, FL
- Buses to Jacksonville, FL from Gainesville, FL
- Buses to Jacksonville, FL from Mobile, AL
- From New York to Jacksonville, FL bus
- Buses Newark to Jacksonville, FL
- Bus Ocala, FL - Jacksonville, FL
- Bus Port Saint Lucie, FL - Jacksonville, FL
- Buses from Raleigh, NC to Jacksonville, FL
- Bus Richmond, VA - Jacksonville, FL
- Buses to Jacksonville, FL from Savannah, GA
- Buses from Springfield, MO to Jacksonville, FL
- Buses Syracuse, NY - Jacksonville, FL
- Bus from Tampa to Jacksonville, FL
- Bus to Jacksonville, FL from Valdosta, GA
- Buses to Jacksonville, FL from Washington, DC
- Bus West Palm Beach, FL to Jacksonville, FL
- Bus Routes to Knoxville, TN
- Buses from Athens, TN to Knoxville, TN
- Buses Austin - Knoxville, TN
- Beaumont, TX to Knoxville, TN bus
- Buses from Chicago to Knoxville, TN
- From Dallas to Knoxville, TN bus
- Buses Detroit - Knoxville, TN
- Bus Durham, NC - Knoxville, TN
- Fayetteville, NC to Knoxville, TN bus
- Buses Greensboro, NC to Knoxville, TN
- Bus to Knoxville, TN from Houston
- Buses Huntington Park, CA to Knoxville, TN
- Buses Los Angeles to Knoxville, TN
- From Philadelphia to Knoxville, TN bus
- Bus from Phoenix, AZ to Knoxville, TN
- Bus to Knoxville, TN from Richmond, VA
- Buses San Jose, CA to Knoxville, TN
- From Shreveport, LA to Knoxville, TN bus
- Bus from St. Louis, MO to Knoxville, TN
- Bus from Tyler, TX to Knoxville, TN
- Warner Robins, GA to Knoxville, TN bus
Popular Airport Shuttles to Jacksonville, FL and to Knoxville, TN
