Bus Chicago to San Antonio, TX - Compare all Companies

Compare all timetables for the bus from Chicago to San Antonio, TX

Here is a selection of the cheapest bus trips from the schedule from Chicago to San Antonio, TX from various bus operators like Greyhound US or FlixBus for the next days.

today

tomorrow

Sunday

$153

Monday

Tuesday

Wednesday

Thursday

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	25h 25m	10:30 PM	Chicago	Downtown Bus Station	11:55 PM	San Antonio, TX	Bus Station	Economy	$153	A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 2/8/2026 10:30:00 PM to Bus Station, San Antonio, TX (USA) arriving at 2/9/2026 11:55:00 PM. 50 Economy ticket for $153 per person are available. Travel duration is 25h 25m
FlixBus	27h 10m	9:45 AM	Chicago	Downtown Bus Station	12:55 PM	San Antonio, TX	Bus Station	Economy	$154	A Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 2/8/2026 9:45:00 AM to Bus Station, San Antonio, TX (USA) arriving at 2/9/2026 12:55:00 PM. 50 Economy ticket for $154 per person are available. Travel duration is 27h 10m
FlixBus	37h 40m	9:45 AM	Chicago	Downtown Bus Station	11:25 PM	San Antonio, TX	Pearl District	Economy	$154	A Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 2/8/2026 9:45:00 AM to Pearl District, San Antonio, TX (USA) arriving at 2/9/2026 11:25:00 PM. 50 Economy ticket for $154 per person are available. Travel duration is 37h 40m
Greyhound US	48h 35m	10:50 PM	Chicago	Downtown Bus Station	11:25 PM	San Antonio, TX	Pearl District	Economy	$154	A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 2/8/2026 10:50:00 PM to Pearl District, San Antonio, TX (USA) arriving at 2/10/2026 11:25:00 PM. 50 Economy ticket for $154 per person are available. Travel duration is 48h 35m
Greyhound US	48h 15m	11:10 PM	Chicago	Union Station	11:25 PM	San Antonio, TX	Pearl District	Economy	$154	A Bus from Greyhound US goes from Union Station, Chicago (USA) at 2/8/2026 11:10:00 PM to Pearl District, San Antonio, TX (USA) arriving at 2/10/2026 11:25:00 PM. 50 Economy ticket for $154 per person are available. Travel duration is 48h 15m

Did you know that if you travel from Chicago to San Antonio, TX via Dallas, you can save more than $19? You can find the corresponding connections below.
- FlixBus
  
  31h 10m
  
  0
  
  5:10 PM
  
  Chicago
  95th Red Line Station
  
  5:15 PM
  
  Dallas
  Bus Station
  
  0
  
  Economy
  
  $100
  
  A Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 2/8/2026 5:10:00 PM to Bus Station, Dallas (USA) arriving at 2/9/2026 5:15:00 PM. 50 Economy ticket for $100 per person are available. Travel duration is 24h 5m
- Busbud
  
  5h 20m
  
  0
  
  7:00 PM
  
  Dallas
  Downtown
  
  12:20 AM
  
  San Antonio, TX
  Pearl District
  
  0
  
  Economy
  
  $34
  
  A Bus from Busbud goes from Downtown, Dallas (USA) at 2/9/2026 7:00:00 PM to Pearl District, San Antonio, TX (USA) arriving at 2/10/2026 12:20:00 AM. 50 Economy ticket for $34 per person are available. Travel duration is 5h 20m
Travel time is 5h 45m longer, but you will save $19

Best Price Offer: The price for the cheapest bus from Chicago to San Antonio, TX is $153 on 2/8/2026. Flexible travelers save on ticket prices.

Facts about the bus from Chicago to San Antonio, TX

Compare all providers like Greyhound US and FlixBus that travel 6 times every day by bus from Chicago to San Antonio, TX in one click! Book your bus ticket from Chicago to San Antonio, TX starting from $153!

Cheapest Bus	$153
Fastest Bus	25h 25m
Earliest Bus	9:45 AM
Latest Bus	11:10 PM
Daily Bus Routes	6 Ø
Distance	1,052.2 miles
Bus Companies	Greyhound US and FlixBus

Cheapest bus connections from Chicago to San Antonio, TX

Every day, 6 buses from 2 bus companies leave Chicago for San Antonio, TX: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 02/06/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 02/01

Monday 02/02

Tuesday 02/03

Wednesday 02/04

Thursday 02/05

Friday 02/06

Saturday 02/07

Sunday 02/08

$153

Monday 02/09

Tuesday 02/10

Wednesday 02/11

Thursday 02/12

Friday 02/13

$184

Saturday 02/14

Sunday 02/15

Monday 02/16

Tuesday 02/17

Wednesday 02/18

Thursday 02/19

Friday 02/20

Saturday 02/21

Sunday 02/22

Monday 02/23

Tuesday 02/24

Wednesday 02/25

Thursday 02/26

Friday 02/27

Saturday 02/28

How to save money travelling from Chicago to San Antonio, TX

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Chicago to San Antonio, TX in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Chicago to San Antonio, TX, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Chicago to San Antonio, TX are also emptier.

Beloved bus companies from Chicago to San Antonio, TX

These are the most booked bus companies between Chicago to San Antonio, TX from our users.

FlixBus from Chicago to San Antonio, TX

Here you will find the key facts about the FlixBus bus route Chicago to San Antonio, TX:

Cheapest Price	$154
Fastest Bus	27h 10m
Earliest Bus	9:45 AM
Last Bus	9:45 AM
Daily Connections	2 Ø
Found on	1/30/2026

Greyhound US from Chicago to San Antonio, TX

Here you will find the key facts about the Greyhound US bus route Chicago to San Antonio, TX:

Cheapest Price	$153
Fastest Bus	25h 25m
Earliest Bus	10:00 AM
Last Bus	11:10 PM
Daily Connections	4 Ø
Found on	1/30/2026

All bus stations and stops in Chicago and San Antonio, TX

In the map below, you can see where to find all bus stations in Chicago and San Antonio, TX.

95th Red Line Station

W. 95th St 14

Downtown Bus Station

West Harrison Street 630-670

Union Station

S Canal St 225

Cumberland CTA

N Cumberland Ave 5800

Canal & Van Buren

S Canal St 310-320

Bus Station

N St Mary's St 500

San Antonio

Pearl District

Avenue A 699-599

W. Southcross & Buffalo Bus Stop

Commerce & Bowie Bus Stop

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Chicago to San Antonio, TX? Compare all modes of transports from Chicago to San Antonio, TX.

Service and Comfort on the bus from Chicago to San Antonio, TX

Want to know which seat classes are available on the buses from Chicago to San Antonio, TX? Or which bus companies serve the route Chicago to San Antonio, TX? Below you will find answers to your questions.

FAQs about the Chicago to San Antonio, TX bus

How much does a Chicago San Antonio, TX bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $153 and takes 25h 25m to reach San Antonio, TX. Compare offers to save money!

How much could I save by comparing buses from Chicago to San Antonio, TX?

This route is offered by 2 companies with a range of ticket prices between $153 and $155. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to San Antonio, TX.

On average, how many connections are available from Chicago to San Antonio, TX each day?

Every day, the Chicago to San Antonio, TX bus route is served by approximately 6 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Chicago to San Antonio, TX take?

The fastest bus from Chicago to San Antonio, TX is offered by Greyhound US and takes 25h 25m. Bus tickets for this connection cost $153. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Chicago to San Antonio, TX?

The earliest bus arriving in San Antonio, TX from Chicago starts at 9:45 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Chicago to San Antonio, TX?

The latest bus trip departing from Chicago for San Antonio, TX starts at 11:10 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Chicago San Antonio, TX route?

When traveling by bus from Chicago to San Antonio, TX, passengers can travel with Greyhound US and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Chicago and San Antonio, TX?

You can check all the direct connections between Chicago and San Antonio, TX by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US and FlixBus.

What can I take with me on the Chicago to San Antonio, TX bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Chicago San Antonio, TX bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Chicago San Antonio, TX bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Chicago to San Antonio, TX on your planned travel date.

How does CheckMyBus find the best bus deals from Chicago to San Antonio, TX?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 6 daily trips between Chicago and San Antonio, TX. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Chicago to San Antonio, TX?

Prices and availability for 6 trips between Chicago and San Antonio, TX change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Chicago to San Antonio, TX

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Chicago and to San Antonio, TX

Here’s an overview of the most popular bus routes to Chicago and to San Antonio, TX. Simply click on the connection of your choice, and you will find all the details about your bus route!