Bus Chicago to San Antonio, TX - Compare all Companies

Compare all timetables for the bus from Chicago to San Antonio, TX

Here is a selection of the cheapest bus trips from the schedule from Chicago to San Antonio, TX from various bus operators like Greyhound US, FlixBus or Tornado Bus Company for the next days.

today

tomorrow

Thursday

$110

Friday

$115

Saturday

$142

Sunday

$136

Monday

$129

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	28h 30m	7:25 PM	Chicago	95th Red Line Station	11:55 PM	San Antonio, TX	Bus Station	Economy	$110	A Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 5/7/2026 7:25:00 PM to Bus Station, San Antonio, TX (USA) arriving at 5/8/2026 11:55:00 PM. 50 Economy ticket for $110 per person are available. Travel duration is 28h 30m
FlixBus	37h 5m	11:50 PM	Chicago	95th Red Line Station	12:55 PM	San Antonio, TX	Bus Station	Economy	$111	A Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 5/7/2026 11:50:00 PM to Bus Station, San Antonio, TX (USA) arriving at 5/9/2026 12:55:00 PM. 50 Economy ticket for $111 per person are available. Travel duration is 37h 5m
Greyhound US	45h 25m	11:45 PM	Chicago	95th Red Line Station	9:10 PM	San Antonio, TX	Pearl District	Economy	$116	A Bus from Greyhound US goes from 95th Red Line Station, Chicago (USA) at 5/7/2026 11:45:00 PM to Pearl District, San Antonio, TX (USA) arriving at 5/9/2026 9:10:00 PM. 50 Economy ticket for $116 per person are available. Travel duration is 45h 25m
Greyhound US	25h 25m	10:30 PM	Chicago	Downtown Bus Station	11:55 PM	San Antonio, TX	Bus Station	Economy	$119	A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 5/7/2026 10:30:00 PM to Bus Station, San Antonio, TX (USA) arriving at 5/8/2026 11:55:00 PM. 50 Economy ticket for $119 per person are available. Travel duration is 25h 25m
Tornado Bus Company	32h 30m	1:30 PM	Chicago	California & 35th Street Bus Stop	10:00 PM	San Antonio, TX	Tornado Bus Company	Basic	$255	A Bus from Tornado Bus Company goes from California & 35th Street Bus Stop, Chicago (USA) at 5/7/2026 1:30:00 PM to Tornado Bus Company, San Antonio, TX (USA) arriving at 5/8/2026 10:00:00 PM. 50 Basic ticket for $255 per person are available. Travel duration is 32h 30m

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	25h 25m	10:30 PM	Chicago	Downtown Bus Station	11:55 PM	San Antonio, TX	Bus Station	Economy	$115	A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 5/8/2026 10:30:00 PM to Bus Station, San Antonio, TX (USA) arriving at 5/9/2026 11:55:00 PM. 50 Economy ticket for $115 per person are available. Travel duration is 25h 25m
FlixBus	35h 25m	9:45 AM	Chicago	Downtown Bus Station	9:10 PM	San Antonio, TX	Pearl District	Economy	$116	A Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 5/8/2026 9:45:00 AM to Pearl District, San Antonio, TX (USA) arriving at 5/9/2026 9:10:00 PM. 50 Economy ticket for $116 per person are available. Travel duration is 35h 25m
FlixBus	27h 10m	9:45 AM	Chicago	Downtown Bus Station	12:55 PM	San Antonio, TX	Bus Station	Economy	$116	A Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 5/8/2026 9:45:00 AM to Bus Station, San Antonio, TX (USA) arriving at 5/9/2026 12:55:00 PM. 50 Economy ticket for $116 per person are available. Travel duration is 27h 10m
Greyhound US	31h 40m	9:55 AM	Chicago	Downtown Bus Station	5:35 PM	San Antonio, TX	Bus Station	Economy	$117	A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 5/8/2026 9:55:00 AM to Bus Station, San Antonio, TX (USA) arriving at 5/9/2026 5:35:00 PM. 50 Economy ticket for $117 per person are available. Travel duration is 31h 40m
Greyhound US	31h 20m	10:15 AM	Chicago	Union Station	5:35 PM	San Antonio, TX	Bus Station	Economy	$117	A Bus from Greyhound US goes from Union Station, Chicago (USA) at 5/8/2026 10:15:00 AM to Bus Station, San Antonio, TX (USA) arriving at 5/9/2026 5:35:00 PM. 50 Economy ticket for $117 per person are available. Travel duration is 31h 20m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	39h 25m	5:45 AM	Chicago	95th Red Line Station	9:10 PM	San Antonio, TX	Pearl District	Economy	$142	A Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 5/9/2026 5:45:00 AM to Pearl District, San Antonio, TX (USA) arriving at 5/10/2026 9:10:00 PM. 50 Economy ticket for $142 per person are available. Travel duration is 39h 25m
FlixBus	31h 10m	5:45 AM	Chicago	95th Red Line Station	12:55 PM	San Antonio, TX	Bus Station	Economy	$148	A Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 5/9/2026 5:45:00 AM to Bus Station, San Antonio, TX (USA) arriving at 5/10/2026 12:55:00 PM. 50 Economy ticket for $148 per person are available. Travel duration is 31h 10m
Greyhound US	47h 40m	11:45 PM	Chicago	95th Red Line Station	11:25 PM	San Antonio, TX	Pearl District	Economy	$150	A Bus from Greyhound US goes from 95th Red Line Station, Chicago (USA) at 5/9/2026 11:45:00 PM to Pearl District, San Antonio, TX (USA) arriving at 5/11/2026 11:25:00 PM. 50 Economy ticket for $150 per person are available. Travel duration is 47h 40m
Greyhound US	31h 40m	9:55 AM	Chicago	Downtown Bus Station	5:35 PM	San Antonio, TX	Bus Station	Economy	$165	A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 5/9/2026 9:55:00 AM to Bus Station, San Antonio, TX (USA) arriving at 5/10/2026 5:35:00 PM. 50 Economy ticket for $165 per person are available. Travel duration is 31h 40m
Tornado Bus Company	23h 45m	1:30 PM	Chicago	California & 35th Street Bus Stop	1:15 PM	San Antonio, TX	Tornado Bus Company	Basic	$255	A Bus from Tornado Bus Company goes from California & 35th Street Bus Stop, Chicago (USA) at 5/9/2026 1:30:00 PM to Tornado Bus Company, San Antonio, TX (USA) arriving at 5/10/2026 1:15:00 PM. 50 Basic ticket for $255 per person are available. Travel duration is 23h 45m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	41h 40m	5:45 AM	Chicago	95th Red Line Station	11:25 PM	San Antonio, TX	Pearl District	Economy	$136	A Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 5/10/2026 5:45:00 AM to Pearl District, San Antonio, TX (USA) arriving at 5/11/2026 11:25:00 PM. 50 Economy ticket for $136 per person are available. Travel duration is 41h 40m
Greyhound US	47h 40m	11:45 PM	Chicago	95th Red Line Station	11:25 PM	San Antonio, TX	Pearl District	Economy	$146	A Bus from Greyhound US goes from 95th Red Line Station, Chicago (USA) at 5/10/2026 11:45:00 PM to Pearl District, San Antonio, TX (USA) arriving at 5/12/2026 11:25:00 PM. 50 Economy ticket for $146 per person are available. Travel duration is 47h 40m
FlixBus	28h 30m	7:25 PM	Chicago	95th Red Line Station	11:55 PM	San Antonio, TX	Bus Station	Economy	$150	A Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 5/10/2026 7:25:00 PM to Bus Station, San Antonio, TX (USA) arriving at 5/11/2026 11:55:00 PM. 50 Economy ticket for $150 per person are available. Travel duration is 28h 30m
Greyhound US	48h 35m	10:50 PM	Chicago	Downtown Bus Station	11:25 PM	San Antonio, TX	Pearl District	Economy	$163	A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 5/10/2026 10:50:00 PM to Pearl District, San Antonio, TX (USA) arriving at 5/12/2026 11:25:00 PM. 50 Economy ticket for $163 per person are available. Travel duration is 48h 35m
Tornado Bus Company	23h 15m	1:30 PM	Chicago	California & 35th Street Bus Stop	12:45 PM	San Antonio, TX	Tornado Bus Company	Basic	$255	A Bus from Tornado Bus Company goes from California & 35th Street Bus Stop, Chicago (USA) at 5/10/2026 1:30:00 PM to Tornado Bus Company, San Antonio, TX (USA) arriving at 5/11/2026 12:45:00 PM. 50 Basic ticket for $255 per person are available. Travel duration is 23h 15m

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	28h 30m	7:25 PM	Chicago	95th Red Line Station	11:55 PM	San Antonio, TX	Bus Station	Economy	$129	A Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 5/11/2026 7:25:00 PM to Bus Station, San Antonio, TX (USA) arriving at 5/12/2026 11:55:00 PM. 50 Economy ticket for $129 per person are available. Travel duration is 28h 30m
FlixBus	37h 5m	11:50 PM	Chicago	95th Red Line Station	12:55 PM	San Antonio, TX	Bus Station	Economy	$129	A Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 5/11/2026 11:50:00 PM to Bus Station, San Antonio, TX (USA) arriving at 5/13/2026 12:55:00 PM. 50 Economy ticket for $129 per person are available. Travel duration is 37h 5m
Greyhound US	31h 40m	9:55 AM	Chicago	Downtown Bus Station	5:35 PM	San Antonio, TX	Bus Station	Economy	$141	A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 5/11/2026 9:55:00 AM to Bus Station, San Antonio, TX (USA) arriving at 5/12/2026 5:35:00 PM. 50 Economy ticket for $141 per person are available. Travel duration is 31h 40m
Greyhound US	25h 25m	10:30 PM	Chicago	Downtown Bus Station	11:55 PM	San Antonio, TX	Bus Station	Economy	$141	A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 5/11/2026 10:30:00 PM to Bus Station, San Antonio, TX (USA) arriving at 5/12/2026 11:55:00 PM. 50 Economy ticket for $141 per person are available. Travel duration is 25h 25m
Tornado Bus Company	23h 30m	1:30 PM	Chicago	California & 35th Street Bus Stop	1:00 PM	San Antonio, TX	Tornado Bus Company	Basic	$255	A Bus from Tornado Bus Company goes from California & 35th Street Bus Stop, Chicago (USA) at 5/11/2026 1:30:00 PM to Tornado Bus Company, San Antonio, TX (USA) arriving at 5/12/2026 1:00:00 PM. 50 Basic ticket for $255 per person are available. Travel duration is 23h 30m

Best Price Offer: The price for the cheapest bus from Chicago to San Antonio, TX is $100 on 5/28/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Chicago and San Antonio, TX

See here how frequent the connections between Chicago and San Antonio, TX are, during different times and days of the week.

Thursday is the busiest day, with more than 36 daily buses from Chicago to San Antonio, TX. Friday has instead the fewest connections, with only 8 daily coaches between Chicago and San Antonio, TX.

The busiest time of the day is the Evening, with 58 buses from Chicago to San Antonio, TX, while Night sees the fewest connections between Chicago and San Antonio, TX, with 16 offers.

Facts about the bus from Chicago to San Antonio, TX

Compare all providers like Greyhound US, FlixBus and Tornado Bus Company that travel 29 times every day by bus from Chicago to San Antonio, TX in one click! Book your bus ticket from Chicago to San Antonio, TX starting from $100!

Cheapest Bus	$100
Fastest Bus	22h 13m
Earliest Bus	5:45 AM
Latest Bus	11:50 PM
Daily Bus Routes	29 Ø
Distance	1,052.2 miles
Bus Companies	Greyhound US, FlixBus and Tornado Bus Company

Cheapest bus connections from Chicago to San Antonio, TX

Every day, 29 buses from 3 bus companies leave Chicago for San Antonio, TX: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 05/05/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 05/03

Monday 05/04

Tuesday 05/05

Wednesday 05/06

Thursday 05/07

$110

Friday 05/08

$115

Saturday 05/09

$142

Sunday 05/10

$136

Monday 05/11

$129

Tuesday 05/12

$127

Wednesday 05/13

$121

Thursday 05/14

$104

Friday 05/15

Saturday 05/16

$104

Sunday 05/17

$101

Monday 05/18

$101

Tuesday 05/19

$123

Wednesday 05/20

$139

Thursday 05/21

$111

Friday 05/22

$117

Saturday 05/23

Sunday 05/24

$127

Monday 05/25

$110

Tuesday 05/26

$134

Wednesday 05/27

$130

Thursday 05/28

$100

Friday 05/29

$141

Saturday 05/30

The cheapest time to travel from Chicago to San Antonio, TX

See here on which day and which time of the day you can find the cheapest bus ticket from Chicago to San Antonio, TX, for the next 30 days.

With a price starting from $100, Thursday is the cheapest day for a bus from Chicago to San Antonio, TX. Friday instead is the most expensive day with prices starting from $115.

Night is the cheapest day time for bus tickets from Chicago to San Antonio, TX, with $100. Afternoon is the most expensive time of the day with prices starting from $252.

How to save money travelling from Chicago to San Antonio, TX

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Chicago to San Antonio, TX in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Chicago to San Antonio, TX, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Chicago to San Antonio, TX are also emptier.

Beloved bus companies from Chicago to San Antonio, TX

These are the most booked bus companies between Chicago to San Antonio, TX from our users.

FlixBus from Chicago to San Antonio, TX

Here you will find the key facts about the FlixBus bus route Chicago to San Antonio, TX:

Cheapest Price	$110
Fastest Bus	27h 10m
Earliest Bus	5:45 AM
Last Bus	11:50 PM
Daily Connections	10 Ø
Found on	5/4/2026

Greyhound US from Chicago to San Antonio, TX

Here you will find the key facts about the Greyhound US bus route Chicago to San Antonio, TX:

Cheapest Price	$115
Fastest Bus	25h 25m
Earliest Bus	9:55 AM
Last Bus	11:10 PM
Daily Connections	11 Ø
Found on	5/4/2026

Tornado Bus Company from Chicago to San Antonio, TX

Here you will find the key facts about the Tornado Bus Company bus route Chicago to San Antonio, TX:

Cheapest Price	$255
Fastest Bus	22h 13m
Earliest Bus	1:30 PM
Last Bus	2:00 PM
Daily Connections	9 Ø
Found on	5/4/2026

All bus stations and stops in Chicago and San Antonio, TX

In the map below, you can see where to find all bus stations in Chicago and San Antonio, TX.

95th Red Line Station

W. 95th St 14

Downtown Bus Station

West Harrison Street 630-670

Union Station

S Canal St 225

Cumberland CTA

N Cumberland Ave 5800

Canal & Van Buren

S Canal St 310-320

Bus Station

N St Mary's St 500

San Antonio

Pearl District

Avenue A 699-599

Commerce & Bowie Bus Stop

W. Southcross & Buffalo Bus Stop

Service and Comfort on the bus from Chicago to San Antonio, TX

Want to know which seat classes are available on the buses from Chicago to San Antonio, TX? Or which bus companies serve the route Chicago to San Antonio, TX? Below you will find answers to your questions.

FAQs about the Chicago to San Antonio, TX bus

How much does a Chicago San Antonio, TX bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $100 and takes 28h 30m to reach San Antonio, TX. Compare offers to save money!

How much could I save by comparing buses from Chicago to San Antonio, TX?

This route is offered by 3 companies with a range of ticket prices between $100 and $255. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to San Antonio, TX.

On average, how many connections are available from Chicago to San Antonio, TX each day?

Every day, the Chicago to San Antonio, TX bus route is served by approximately 29 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Chicago to San Antonio, TX take?

The fastest bus from Chicago to San Antonio, TX is offered by Tornado Bus Company and takes 22h 13m. Bus tickets for this connection cost $255. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Chicago to San Antonio, TX?

The earliest bus arriving in San Antonio, TX from Chicago starts at 5:45 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Chicago to San Antonio, TX?

The latest bus trip departing from Chicago for San Antonio, TX starts at 11:50 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Chicago San Antonio, TX route?

When traveling by bus from Chicago to San Antonio, TX, passengers can travel with Greyhound US, FlixBus and Tornado Bus Company. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Chicago and San Antonio, TX?

You can check all the direct connections between Chicago and San Antonio, TX by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US, FlixBus and Tornado Bus Company.

What can I take with me on the Chicago to San Antonio, TX bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Chicago San Antonio, TX bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Chicago San Antonio, TX bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Chicago to San Antonio, TX on your planned travel date.

How does CheckMyBus find the best bus deals from Chicago to San Antonio, TX?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 29 daily trips between Chicago and San Antonio, TX. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Chicago to San Antonio, TX?

Prices and availability for 29 trips between Chicago and San Antonio, TX change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Chicago to San Antonio, TX

Basic

Name referring to the typical seat you will find with companies that don’t distinguish between different classes.

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Chicago and to San Antonio, TX

Here’s an overview of the most popular bus routes to Chicago and to San Antonio, TX. Simply click on the connection of your choice, and you will find all the details about your bus route!