Bus Chicago to San Antonio, TX - Compare all Companies

Compare all timetables for the bus from Chicago to San Antonio, TX

Here is a selection of the cheapest bus trips from the schedule from Chicago to San Antonio, TX from various bus operators like Greyhound US, FlixBus or Tornado Bus Company for the next days.

today

$176

tomorrow

$192

Saturday

$168

Sunday

Monday

$162

Tuesday

Wednesday

$174

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	37h 15m	10:10 AM	Chicago	95th Red Line Station	11:25 PM	San Antonio, TX	Pearl District	Economy	$176	A Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 12/4/2025 10:10:00 AM to Pearl District, San Antonio, TX (USA) arriving at 12/5/2025 11:25:00 PM. 50 Economy ticket for $176 per person are available. Travel duration is 37h 15m
FlixBus	49h 45m	7:25 PM	Chicago	95th Red Line Station	9:10 PM	San Antonio, TX	Pearl District	Economy	$177	A Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 12/4/2025 7:25:00 PM to Pearl District, San Antonio, TX (USA) arriving at 12/6/2025 9:10:00 PM. 50 Economy ticket for $177 per person are available. Travel duration is 49h 45m
Greyhound US	48h 55m	10:30 PM	Chicago	95th Red Line Station	11:25 PM	San Antonio, TX	Pearl District	Economy	$188	A Bus from Greyhound US goes from 95th Red Line Station, Chicago (USA) at 12/4/2025 10:30:00 PM to Pearl District, San Antonio, TX (USA) arriving at 12/6/2025 11:25:00 PM. 50 Economy ticket for $188 per person are available. Travel duration is 48h 55m
Greyhound US	46h 40m	10:30 PM	Chicago	Downtown Bus Station	9:10 PM	San Antonio, TX	Pearl District	Economy	$194	A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 12/4/2025 10:30:00 PM to Pearl District, San Antonio, TX (USA) arriving at 12/6/2025 9:10:00 PM. 50 Economy ticket for $194 per person are available. Travel duration is 46h 40m
Tornado Bus Company	23h 15m	1:30 PM	Chicago	California & 35th Street Bus Stop	12:45 PM	San Antonio, TX	Tornado Bus Company	Basic	$275	A Bus from Tornado Bus Company goes from California & 35th Street Bus Stop, Chicago (USA) at 12/4/2025 1:30:00 PM to Tornado Bus Company, San Antonio, TX (USA) arriving at 12/5/2025 12:45:00 PM. 50 Basic ticket for $275 per person are available. Travel duration is 23h 15m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	25h 20m	10:30 PM	Chicago	Downtown Bus Station	11:50 PM	San Antonio, TX	Bus Station	Economy	$192	A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 12/5/2025 10:30:00 PM to Bus Station, San Antonio, TX (USA) arriving at 12/6/2025 11:50:00 PM. 50 Economy ticket for $192 per person are available. Travel duration is 25h 20m
FlixBus	37h 40m	9:45 AM	Chicago	Downtown Bus Station	11:25 PM	San Antonio, TX	Pearl District	Economy	$193	A Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 12/5/2025 9:45:00 AM to Pearl District, San Antonio, TX (USA) arriving at 12/6/2025 11:25:00 PM. 50 Economy ticket for $193 per person are available. Travel duration is 37h 40m
Greyhound US	46h 40m	10:30 PM	Chicago	Downtown Bus Station	9:10 PM	San Antonio, TX	Pearl District	Economy	$193	A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 12/5/2025 10:30:00 PM to Pearl District, San Antonio, TX (USA) arriving at 12/7/2025 9:10:00 PM. 50 Economy ticket for $193 per person are available. Travel duration is 46h 40m
Greyhound US	31h 35m	10:00 AM	Chicago	Union Station	5:35 PM	San Antonio, TX	Bus Station	Economy	$193	A Bus from Greyhound US goes from Union Station, Chicago (USA) at 12/5/2025 10:00:00 AM to Bus Station, San Antonio, TX (USA) arriving at 12/6/2025 5:35:00 PM. 50 Economy ticket for $193 per person are available. Travel duration is 31h 35m
FlixBus	27h 10m	9:45 AM	Chicago	Downtown Bus Station	12:55 PM	San Antonio, TX	Bus Station	Economy	$205	A Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 12/5/2025 9:45:00 AM to Bus Station, San Antonio, TX (USA) arriving at 12/6/2025 12:55:00 PM. 50 Economy ticket for $205 per person are available. Travel duration is 27h 10m

Did you know that if you travel from Chicago to San Antonio, TX via Dallas, you can save more than $34? You can find the corresponding connections below.
- Busbud
  
  35h 0m
  
  0
  
  10:10 AM
  
  Chicago
  95th Red Line Station
  
  6:20 AM
  
  Dallas
  Bus Station
  
  0
  
  Economy
  
  $127
  
  A Bus from Busbud goes from 95th Red Line Station, Chicago (USA) at 12/5/2025 10:10:00 AM to Bus Station, Dallas (USA) arriving at 12/6/2025 6:20:00 AM. 50 Economy ticket for $127 per person are available. Travel duration is 20h 10m
- Busbud
  
  5h 40m
  
  0
  
  3:30 PM
  
  Dallas
  Downtown
  
  9:10 PM
  
  San Antonio, TX
  Pearl District
  
  0
  
  Economy
  
  $31
  
  A Bus from Busbud goes from Downtown, Dallas (USA) at 12/6/2025 3:30:00 PM to Pearl District, San Antonio, TX (USA) arriving at 12/6/2025 9:10:00 PM. 50 Economy ticket for $31 per person are available. Travel duration is 5h 40m
Travel time is 9h 40m longer, but you will save $34

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	37h 40m	9:45 AM	Chicago	Downtown Bus Station	11:25 PM	San Antonio, TX	Pearl District	Economy	$168	A Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 12/6/2025 9:45:00 AM to Pearl District, San Antonio, TX (USA) arriving at 12/7/2025 11:25:00 PM. 50 Economy ticket for $168 per person are available. Travel duration is 37h 40m
FlixBus	27h 10m	9:45 AM	Chicago	Downtown Bus Station	12:55 PM	San Antonio, TX	Bus Station	Economy	$169	A Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 12/6/2025 9:45:00 AM to Bus Station, San Antonio, TX (USA) arriving at 12/7/2025 12:55:00 PM. 50 Economy ticket for $169 per person are available. Travel duration is 27h 10m
Greyhound US	48h 55m	10:30 PM	Chicago	Downtown Bus Station	11:25 PM	San Antonio, TX	Pearl District	Economy	$169	A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 12/6/2025 10:30:00 PM to Pearl District, San Antonio, TX (USA) arriving at 12/8/2025 11:25:00 PM. 50 Economy ticket for $169 per person are available. Travel duration is 48h 55m
Greyhound US	25h 20m	10:30 PM	Chicago	Downtown Bus Station	11:50 PM	San Antonio, TX	Bus Station	Economy	$170	A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 12/6/2025 10:30:00 PM to Bus Station, San Antonio, TX (USA) arriving at 12/7/2025 11:50:00 PM. 50 Economy ticket for $170 per person are available. Travel duration is 25h 20m
Greyhound US	31h 35m	10:00 AM	Chicago	Union Station	5:35 PM	San Antonio, TX	Bus Station	Economy	$174	A Bus from Greyhound US goes from Union Station, Chicago (USA) at 12/6/2025 10:00:00 AM to Bus Station, San Antonio, TX (USA) arriving at 12/7/2025 5:35:00 PM. 50 Economy ticket for $174 per person are available. Travel duration is 31h 35m

Did you know that if you travel from Chicago to San Antonio, TX via Dallas, you can save more than $19? You can find the corresponding connections below.
- Busbud
  
  26h 45m
  
  0
  
  10:10 AM
  
  Chicago
  95th Red Line Station
  
  6:20 AM
  
  Dallas
  Bus Station
  
  0
  
  Economy
  
  $113
  
  A Bus from Busbud goes from 95th Red Line Station, Chicago (USA) at 12/8/2025 10:10:00 AM to Bus Station, Dallas (USA) arriving at 12/9/2025 6:20:00 AM. 50 Economy ticket for $113 per person are available. Travel duration is 20h 10m
- FlixBus
  
  5h 40m
  
  0
  
  7:15 AM
  
  Dallas
  Bus Station
  
  12:55 PM
  
  San Antonio, TX
  Bus Station
  
  0
  
  Economy
  
  $36
  
  A Bus from FlixBus goes from Bus Station, Dallas (USA) at 12/9/2025 7:15:00 AM to Bus Station, San Antonio, TX (USA) arriving at 12/9/2025 12:55:00 PM. 50 Economy ticket for $36 per person are available. Travel duration is 5h 40m
Travel time is 1h 25m longer, but you will save $19

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	37h 40m	9:45 AM	Chicago	Downtown Bus Station	11:25 PM	San Antonio, TX	Pearl District	Economy	$162	A Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 12/8/2025 9:45:00 AM to Pearl District, San Antonio, TX (USA) arriving at 12/9/2025 11:25:00 PM. 50 Economy ticket for $162 per person are available. Travel duration is 37h 40m
FlixBus	27h 10m	9:45 AM	Chicago	Downtown Bus Station	12:55 PM	San Antonio, TX	Bus Station	Economy	$163	A Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 12/8/2025 9:45:00 AM to Bus Station, San Antonio, TX (USA) arriving at 12/9/2025 12:55:00 PM. 50 Economy ticket for $163 per person are available. Travel duration is 27h 10m
Greyhound US	25h 25m	10:30 PM	Chicago	Downtown Bus Station	11:55 PM	San Antonio, TX	Bus Station	Economy	$163	A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 12/8/2025 10:30:00 PM to Bus Station, San Antonio, TX (USA) arriving at 12/9/2025 11:55:00 PM. 50 Economy ticket for $163 per person are available. Travel duration is 25h 25m
Greyhound US	31h 35m	10:00 AM	Chicago	Union Station	5:35 PM	San Antonio, TX	Bus Station	Economy	$164	A Bus from Greyhound US goes from Union Station, Chicago (USA) at 12/8/2025 10:00:00 AM to Bus Station, San Antonio, TX (USA) arriving at 12/9/2025 5:35:00 PM. 50 Economy ticket for $164 per person are available. Travel duration is 31h 35m
Greyhound US	46h 40m	10:30 PM	Chicago	Downtown Bus Station	9:10 PM	San Antonio, TX	Pearl District	Economy	$167	A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 12/8/2025 10:30:00 PM to Pearl District, San Antonio, TX (USA) arriving at 12/10/2025 9:10:00 PM. 50 Economy ticket for $167 per person are available. Travel duration is 46h 40m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	49h 25m	10:00 PM	Chicago	Union Station	11:25 PM	San Antonio, TX	Pearl District	Economy	$174	A Bus from Greyhound US goes from Union Station, Chicago (USA) at 12/10/2025 10:00:00 PM to Pearl District, San Antonio, TX (USA) arriving at 12/12/2025 11:25:00 PM. 50 Economy ticket for $174 per person are available. Travel duration is 49h 25m
Greyhound US	30h 45m	6:10 AM	Chicago	Downtown Bus Station	12:55 PM	San Antonio, TX	Bus Station	Economy	$177	A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 12/10/2025 6:10:00 AM to Bus Station, San Antonio, TX (USA) arriving at 12/11/2025 12:55:00 PM. 50 Economy ticket for $177 per person are available. Travel duration is 30h 45m
Greyhound US	31h 55m	9:40 AM	Chicago	Downtown Bus Station	5:35 PM	San Antonio, TX	Bus Station	Economy	$179	A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 12/10/2025 9:40:00 AM to Bus Station, San Antonio, TX (USA) arriving at 12/11/2025 5:35:00 PM. 50 Economy ticket for $179 per person are available. Travel duration is 31h 55m
Greyhound US	31h 35m	10:00 AM	Chicago	Union Station	5:35 PM	San Antonio, TX	Bus Station	Economy	$179	A Bus from Greyhound US goes from Union Station, Chicago (USA) at 12/10/2025 10:00:00 AM to Bus Station, San Antonio, TX (USA) arriving at 12/11/2025 5:35:00 PM. 50 Economy ticket for $179 per person are available. Travel duration is 31h 35m
Greyhound US	46h 40m	10:30 PM	Chicago	Downtown Bus Station	9:10 PM	San Antonio, TX	Pearl District	Economy	$181	A Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 12/10/2025 10:30:00 PM to Pearl District, San Antonio, TX (USA) arriving at 12/12/2025 9:10:00 PM. 50 Economy ticket for $181 per person are available. Travel duration is 46h 40m

Did you know that if you travel from Chicago to San Antonio, TX via Dallas, you can save more than $35? You can find the corresponding connections below.
- Busbud
  
  33h 15m
  
  0
  
  2:10 PM
  
  Chicago
  95th Red Line Station
  
  5:15 PM
  
  Dallas
  Bus Station
  
  0
  
  Economy
  
  $107
  
  A Bus from Busbud goes from 95th Red Line Station, Chicago (USA) at 12/10/2025 2:10:00 PM to Bus Station, Dallas (USA) arriving at 12/11/2025 5:15:00 PM. 50 Economy ticket for $107 per person are available. Travel duration is 27h 5m
- Busbud
  
  5h 30m
  
  0
  
  5:55 PM
  
  Dallas
  Downtown
  
  11:25 PM
  
  San Antonio, TX
  Pearl District
  
  0
  
  Economy
  
  $32
  
  A Bus from Busbud goes from Downtown, Dallas (USA) at 12/11/2025 5:55:00 PM to Pearl District, San Antonio, TX (USA) arriving at 12/11/2025 11:25:00 PM. 50 Economy ticket for $32 per person are available. Travel duration is 5h 30m
Travel time is 2h 30m longer, but you will save $35

Best Price Offer: The price for the cheapest bus from Chicago to San Antonio, TX is $119 on 12/25/2025. Flexible travelers save on ticket prices.

Frequency of bus connections between Chicago and San Antonio, TX

See here how frequent the connections between Chicago and San Antonio, TX are, during different times and days of the week.

Thursday is the busiest day, with more than 31 daily buses from Chicago to San Antonio, TX. Friday has instead the fewest connections, with only 5 daily coaches between Chicago and San Antonio, TX.

The busiest time of the day is the Morning, with 22 buses from Chicago to San Antonio, TX, while Afternoon sees the fewest connections between Chicago and San Antonio, TX, with 9 offers.

Facts about the bus from Chicago to San Antonio, TX

Compare all providers like Greyhound US, FlixBus and Tornado Bus Company that travel 10 times every day by bus from Chicago to San Antonio, TX in one click! Book your bus ticket from Chicago to San Antonio, TX starting from $119!

Cheapest Bus	$119
Fastest Bus	22h 13m
Earliest Bus	9:45 AM
Latest Bus	10:30 PM
Daily Bus Routes	10 Ø
Distance	1,052.2 miles
Bus Companies	Greyhound US, FlixBus and Tornado Bus Company

Cheapest bus connections from Chicago to San Antonio, TX

Every day, 10 buses from 3 bus companies leave Chicago for San Antonio, TX: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/04/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 11/30

Monday 12/01

Tuesday 12/02

Wednesday 12/03

Thursday 12/04

$176

Friday 12/05

$192

Saturday 12/06

$168

Sunday 12/07

Monday 12/08

$162

Tuesday 12/09

Wednesday 12/10

$174

Thursday 12/11

$181

Friday 12/12

Saturday 12/13

Sunday 12/14

Monday 12/15

Tuesday 12/16

Wednesday 12/17

Thursday 12/18

Friday 12/19

Saturday 12/20

Sunday 12/21

Monday 12/22

Tuesday 12/23

Wednesday 12/24

Thursday 12/25

$119

Friday 12/26

Saturday 12/27

The cheapest time to travel from Chicago to San Antonio, TX

See here on which day and which time of the day you can find the cheapest bus ticket from Chicago to San Antonio, TX, for the next 30 days.

With a price starting from $119, Thursday is the cheapest day for a bus from Chicago to San Antonio, TX. Friday instead is the most expensive day with prices starting from $192.

Morning is the cheapest day time for bus tickets from Chicago to San Antonio, TX, with $162. Afternoon is the most expensive time of the day with prices starting from $272.

How to save money travelling from Chicago to San Antonio, TX

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Chicago to San Antonio, TX in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Chicago to San Antonio, TX, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Chicago to San Antonio, TX are also emptier.

Beloved bus companies from Chicago to San Antonio, TX

These are the most booked bus companies between Chicago to San Antonio, TX from our users.

FlixBus from Chicago to San Antonio, TX

Here you will find the key facts about the FlixBus bus route Chicago to San Antonio, TX:

Cheapest Price	$162
Fastest Bus	26h 45m
Earliest Bus	9:45 AM
Last Bus	9:45 AM
Daily Connections	5 Ø
Found on	11/29/2025

Greyhound US from Chicago to San Antonio, TX

Here you will find the key facts about the Greyhound US bus route Chicago to San Antonio, TX:

Cheapest Price	$163
Fastest Bus	25h 20m
Earliest Bus	10:00 AM
Last Bus	10:30 PM
Daily Connections	4 Ø
Found on	12/1/2025

All bus stations and stops in Chicago and San Antonio, TX

In the map below, you can see where to find all bus stations in Chicago and San Antonio, TX.

95th Red Line Station

W. 95th St 14

Downtown Bus Station

West Harrison Street 630-670

Union Station

S Canal St 225

Cumberland CTA

N Cumberland Ave 5800

California & Cermak Bus Stop

S California Ave 2139

Bus Station

N St Mary's St 500

San Antonio

Pearl District

Avenue A 699-599

W. Southcross & Buffalo Bus Stop

Commerce & Bowie Bus Stop

Compare the bus with other modes of transport

The bus is often the cheapest mode of transport, while other modes like train or flight are faster. Looking for quicker alternatives to travel from Chicago to San Antonio, TX? Compare all modes of transports from Chicago to San Antonio, TX.

Service and Comfort on the bus from Chicago to San Antonio, TX

Want to know which seat classes are available on the buses from Chicago to San Antonio, TX? Or which bus companies serve the route Chicago to San Antonio, TX? Below you will find answers to your questions.

FAQs about the Chicago to San Antonio, TX bus

How much does a Chicago San Antonio, TX bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $119 and takes 37h 40m to reach San Antonio, TX. Compare offers to save money!

How much could I save by comparing buses from Chicago to San Antonio, TX?

This route is offered by 3 companies with a range of ticket prices between $119 and $275. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to San Antonio, TX.

On average, how many connections are available from Chicago to San Antonio, TX each day?

Every day, the Chicago to San Antonio, TX bus route is served by approximately 10 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Chicago to San Antonio, TX take?

The fastest bus from Chicago to San Antonio, TX is offered by Tornado Bus Company and takes 22h 13m. Bus tickets for this connection cost $275. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Chicago to San Antonio, TX?

The earliest bus arriving in San Antonio, TX from Chicago starts at 9:45 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Chicago to San Antonio, TX?

The latest bus trip departing from Chicago for San Antonio, TX starts at 10:30 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Chicago San Antonio, TX route?

When traveling by bus from Chicago to San Antonio, TX, passengers can travel with Greyhound US, FlixBus and Tornado Bus Company. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Chicago and San Antonio, TX?

You can check all the direct connections between Chicago and San Antonio, TX by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US, FlixBus and Tornado Bus Company.

What can I take with me on the Chicago to San Antonio, TX bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Chicago San Antonio, TX bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Chicago San Antonio, TX bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Chicago to San Antonio, TX on your planned travel date.

Available seat classes which are offered on the bus route Chicago to San Antonio, TX

Basic

Name referring to the typical seat you will find with companies that don’t distinguish between different classes.

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Chicago and to San Antonio, TX

Here’s an overview of the most popular bus routes to Chicago and to San Antonio, TX. Simply click on the connection of your choice, and you will find all the details about your bus route!