What is the best way to travel from Chicago to San Antonio, TX?
Looking for a trip? Compare all the available Flights and Buses for the journey to San Antonio, TX from Chicago. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 3 available companies to find your perfect trip!
What is the cheapest way to reach San Antonio, TX from Chicago?
You can get to San Antonio, TX with just $81 by taking a Bus from FlixBus, but you can find many more cheap offers: we have selected the best ones for next few days here for you.
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FlixBus34h 20m06:40 PMChicago95th Red Line Station5:00 AMSan Antonio, TXBus Station0EconomyA Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 6/2/2026 6:40:00 PM to Bus Station, San Antonio, TX (USA) arriving at 6/4/2026 5:00:00 AM. 50 Economy ticket for $85 per person are available. Travel duration is 34h 20m
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FlixBus31h 10m05:45 AMChicago95th Red Line Station12:55 PMSan Antonio, TXBus Station0EconomyA Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 6/2/2026 5:45:00 AM to Bus Station, San Antonio, TX (USA) arriving at 6/3/2026 12:55:00 PM. 50 Economy ticket for $86 per person are available. Travel duration is 31h 10m
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Greyhound US25h 25m010:30 PMChicagoDowntown Bus Station11:55 PMSan Antonio, TXBus Station0EconomyA Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 6/2/2026 10:30:00 PM to Bus Station, San Antonio, TX (USA) arriving at 6/3/2026 11:55:00 PM. 50 Economy ticket for $101 per person are available. Travel duration is 25h 25m
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Greyhound US31h 40m09:55 AMChicagoDowntown Bus Station5:35 PMSan Antonio, TXBus Station0EconomyA Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 6/2/2026 9:55:00 AM to Bus Station, San Antonio, TX (USA) arriving at 6/3/2026 5:35:00 PM. 50 Economy ticket for $102 per person are available. Travel duration is 31h 40m
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Tornado Bus Company23h 15m01:30 PMChicagoCalifornia & 35th Street Bus Stop12:45 PMSan Antonio, TXTornado Bus Company0BasicA Bus from Tornado Bus Company goes from California & 35th Street Bus Stop, Chicago (USA) at 6/2/2026 1:30:00 PM to Tornado Bus Company, San Antonio, TX (USA) arriving at 6/3/2026 12:45:00 PM. 50 Basic ticket for $255 per person are available. Travel duration is 23h 15m
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United Airlines3h 2m09:10 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center12:12 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from United Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/2/2026 9:10:00 AM to San Antonio Airport, San Antonio Airport (USA) arriving at 6/2/2026 12:12:00 PM. 50 Economy ticket for $148 per person are available. Travel duration is 3h 2m
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Frontier Airlines21h 22m09:37 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center6:59 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Frontier Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/2/2026 9:37:00 PM to San Antonio Airport, San Antonio Airport (USA) arriving at 6/3/2026 6:59:00 PM. 50 Economy ticket for $175 per person are available. Travel duration is 21h 22m
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Volaris8h 45m07:35 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center4:20 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Volaris goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/2/2026 7:35:00 AM to San Antonio Airport, San Antonio Airport (USA) arriving at 6/2/2026 4:20:00 PM. 50 Economy ticket for $347 per person are available. Travel duration is 8h 45m
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Alaska Airlines11h 56m05:44 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center5:40 AMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Alaska Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/2/2026 5:44:00 PM to San Antonio Airport, San Antonio Airport (USA) arriving at 6/3/2026 5:40:00 AM. 50 Economy ticket for $379 per person are available. Travel duration is 11h 56m
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Viva Aerobus8h 45m01:30 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center10:15 AMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Viva Aerobus goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/2/2026 1:30:00 AM to San Antonio Airport, San Antonio Airport (USA) arriving at 6/2/2026 10:15:00 AM. 50 Economy ticket for $432 per person are available. Travel duration is 8h 45m
Cheapest Buses Tuesday
Cheapest Flights Tuesday
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FlixBus31h 10m05:45 AMChicago95th Red Line Station12:55 PMSan Antonio, TXBus Station0EconomyA Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 6/3/2026 5:45:00 AM to Bus Station, San Antonio, TX (USA) arriving at 6/4/2026 12:55:00 PM. 50 Economy ticket for $81 per person are available. Travel duration is 31h 10m
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FlixBus28h 30m07:25 PMChicago95th Red Line Station11:55 PMSan Antonio, TXBus Station0EconomyA Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 6/3/2026 7:25:00 PM to Bus Station, San Antonio, TX (USA) arriving at 6/4/2026 11:55:00 PM. 50 Economy ticket for $81 per person are available. Travel duration is 28h 30m
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Greyhound US45h 25m011:45 PMChicago95th Red Line Station9:10 PMSan Antonio, TXPearl District0EconomyA Bus from Greyhound US goes from 95th Red Line Station, Chicago (USA) at 6/3/2026 11:45:00 PM to Pearl District, San Antonio, TX (USA) arriving at 6/5/2026 9:10:00 PM. 50 Economy ticket for $89 per person are available. Travel duration is 45h 25m
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Greyhound US25h 25m010:30 PMChicagoDowntown Bus Station11:55 PMSan Antonio, TXBus Station0EconomyA Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 6/3/2026 10:30:00 PM to Bus Station, San Antonio, TX (USA) arriving at 6/4/2026 11:55:00 PM. 50 Economy ticket for $91 per person are available. Travel duration is 25h 25m
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Tornado Bus Company23h 45m01:30 PMChicagoCalifornia & 35th Street Bus Stop1:15 PMSan Antonio, TXTornado Bus Company0BasicA Bus from Tornado Bus Company goes from California & 35th Street Bus Stop, Chicago (USA) at 6/3/2026 1:30:00 PM to Tornado Bus Company, San Antonio, TX (USA) arriving at 6/4/2026 1:15:00 PM. 50 Basic ticket for $255 per person are available. Travel duration is 23h 45m
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Frontier Airlines21h 22m09:37 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center6:59 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Frontier Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/3/2026 9:37:00 PM to San Antonio Airport, San Antonio Airport (USA) arriving at 6/4/2026 6:59:00 PM. 50 Economy ticket for $130 per person are available. Travel duration is 21h 22m
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United Airlines3h 0m01:30 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center4:30 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from United Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/3/2026 1:30:00 PM to San Antonio Airport, San Antonio Airport (USA) arriving at 6/3/2026 4:30:00 PM. 50 Economy ticket for $147 per person are available. Travel duration is 3h 0m
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Skyscanner3h 13m09:10 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center12:23 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Skyscanner goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/3/2026 9:10:00 AM to San Antonio Airport, San Antonio Airport (USA) arriving at 6/3/2026 12:23:00 PM. 50 Economy ticket for $147 per person are available. Travel duration is 3h 13m
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Volaris8h 45m07:35 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center4:20 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Volaris goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/3/2026 7:35:00 AM to San Antonio Airport, San Antonio Airport (USA) arriving at 6/3/2026 4:20:00 PM. 50 Economy ticket for $353 per person are available. Travel duration is 8h 45m
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Alaska Airlines11h 1m06:00 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center5:01 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Alaska Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/3/2026 6:00:00 AM to San Antonio Airport, San Antonio Airport (USA) arriving at 6/3/2026 5:01:00 PM. 50 Economy ticket for $372 per person are available. Travel duration is 11h 1m
Cheapest Buses Wednesday
Cheapest Flights Wednesday
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Frontier Airlines21h 22m09:37 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center6:59 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Frontier Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/4/2026 9:37:00 PM to San Antonio Airport, San Antonio Airport (USA) arriving at 6/5/2026 6:59:00 PM. 50 Economy ticket for $130 per person are available. Travel duration is 21h 22m
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United Airlines3h 2m09:10 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center12:12 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from United Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/4/2026 9:10:00 AM to San Antonio Airport, San Antonio Airport (USA) arriving at 6/4/2026 12:12:00 PM. 50 Economy ticket for $154 per person are available. Travel duration is 3h 2m
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Sun Country Airlines15h 16m06:25 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center9:41 AMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Sun Country Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/4/2026 6:25:00 PM to San Antonio Airport, San Antonio Airport (USA) arriving at 6/5/2026 9:41:00 AM. 50 Economy ticket for $193 per person are available. Travel duration is 15h 16m
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Volaris14h 40m01:40 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center4:20 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Volaris goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/4/2026 1:40:00 AM to San Antonio Airport, San Antonio Airport (USA) arriving at 6/4/2026 4:20:00 PM. 50 Economy ticket for $352 per person are available. Travel duration is 14h 40m
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Alaska Airlines11h 56m05:44 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center5:40 AMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Alaska Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/4/2026 5:44:00 PM to San Antonio Airport, San Antonio Airport (USA) arriving at 6/5/2026 5:40:00 AM. 50 Economy ticket for $373 per person are available. Travel duration is 11h 56m
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FlixBus27h 10m09:45 AMChicagoDowntown Bus Station12:55 PMSan Antonio, TXBus Station0EconomyA Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 6/4/2026 9:45:00 AM to Bus Station, San Antonio, TX (USA) arriving at 6/5/2026 12:55:00 PM. 50 Economy ticket for $131 per person are available. Travel duration is 27h 10m
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FlixBus35h 25m09:45 AMChicagoDowntown Bus Station9:10 PMSan Antonio, TXPearl District0EconomyA Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 6/4/2026 9:45:00 AM to Pearl District, San Antonio, TX (USA) arriving at 6/5/2026 9:10:00 PM. 50 Economy ticket for $132 per person are available. Travel duration is 35h 25m
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Greyhound US31h 40m09:55 AMChicagoDowntown Bus Station5:35 PMSan Antonio, TXBus Station0EconomyA Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 6/4/2026 9:55:00 AM to Bus Station, San Antonio, TX (USA) arriving at 6/5/2026 5:35:00 PM. 50 Economy ticket for $133 per person are available. Travel duration is 31h 40m
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Greyhound US25h 25m010:30 PMChicagoDowntown Bus Station11:55 PMSan Antonio, TXBus Station0EconomyA Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 6/4/2026 10:30:00 PM to Bus Station, San Antonio, TX (USA) arriving at 6/5/2026 11:55:00 PM. 50 Economy ticket for $133 per person are available. Travel duration is 25h 25m
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Greyhound US31h 20m010:15 AMChicagoUnion Station5:35 PMSan Antonio, TXBus Station0EconomyA Bus from Greyhound US goes from Union Station, Chicago (USA) at 6/4/2026 10:15:00 AM to Bus Station, San Antonio, TX (USA) arriving at 6/5/2026 5:35:00 PM. 50 Economy ticket for $133 per person are available. Travel duration is 31h 20m
Cheapest Flights Thursday
Cheapest Buses Thursday
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FlixBus28h 30m07:25 PMChicago95th Red Line Station11:55 PMSan Antonio, TXBus Station0EconomyA Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 6/5/2026 7:25:00 PM to Bus Station, San Antonio, TX (USA) arriving at 6/6/2026 11:55:00 PM. 50 Economy ticket for $94 per person are available. Travel duration is 28h 30m
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FlixBus31h 10m05:45 AMChicago95th Red Line Station12:55 PMSan Antonio, TXBus Station0EconomyA Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 6/5/2026 5:45:00 AM to Bus Station, San Antonio, TX (USA) arriving at 6/6/2026 12:55:00 PM. 50 Economy ticket for $97 per person are available. Travel duration is 31h 10m
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Greyhound US45h 25m011:45 PMChicago95th Red Line Station9:10 PMSan Antonio, TXPearl District0EconomyA Bus from Greyhound US goes from 95th Red Line Station, Chicago (USA) at 6/5/2026 11:45:00 PM to Pearl District, San Antonio, TX (USA) arriving at 6/7/2026 9:10:00 PM. 50 Economy ticket for $106 per person are available. Travel duration is 45h 25m
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Greyhound US25h 25m010:30 PMChicagoDowntown Bus Station11:55 PMSan Antonio, TXBus Station0EconomyA Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 6/5/2026 10:30:00 PM to Bus Station, San Antonio, TX (USA) arriving at 6/6/2026 11:55:00 PM. 50 Economy ticket for $118 per person are available. Travel duration is 25h 25m
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Tornado Bus Company23h 30m01:30 PMChicagoCalifornia & 35th Street Bus Stop1:00 PMSan Antonio, TXTornado Bus Company0EconomyA Bus from Tornado Bus Company goes from California & 35th Street Bus Stop, Chicago (USA) at 6/5/2026 1:30:00 PM to Tornado Bus Company, San Antonio, TX (USA) arriving at 6/6/2026 1:00:00 PM. 50 Economy ticket for $255 per person are available. Travel duration is 23h 30m
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Frontier Airlines21h 22m09:37 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center6:59 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Frontier Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/5/2026 9:37:00 PM to San Antonio Airport, San Antonio Airport (USA) arriving at 6/6/2026 6:59:00 PM. 50 Economy ticket for $130 per person are available. Travel duration is 21h 22m
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United Airlines3h 2m09:10 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center12:12 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from United Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/5/2026 9:10:00 AM to San Antonio Airport, San Antonio Airport (USA) arriving at 6/5/2026 12:12:00 PM. 50 Economy ticket for $202 per person are available. Travel duration is 3h 2m
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Volaris8h 45m07:35 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center4:20 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Volaris goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/5/2026 7:35:00 AM to San Antonio Airport, San Antonio Airport (USA) arriving at 6/5/2026 4:20:00 PM. 50 Economy ticket for $338 per person are available. Travel duration is 8h 45m
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Alaska Airlines11h 56m05:44 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center5:40 AMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Alaska Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/5/2026 5:44:00 PM to San Antonio Airport, San Antonio Airport (USA) arriving at 6/6/2026 5:40:00 AM. 50 Economy ticket for $373 per person are available. Travel duration is 11h 56m
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Viva Aerobus8h 45m01:30 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center10:15 AMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Viva Aerobus goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/5/2026 1:30:00 AM to San Antonio Airport, San Antonio Airport (USA) arriving at 6/5/2026 10:15:00 AM. 50 Economy ticket for $504 per person are available. Travel duration is 8h 45m
Cheapest Buses Friday
Cheapest Flights Friday
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Frontier Airlines21h 22m09:37 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center6:59 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Frontier Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/6/2026 9:37:00 PM to San Antonio Airport, San Antonio Airport (USA) arriving at 6/7/2026 6:59:00 PM. 50 Economy ticket for $129 per person are available. Travel duration is 21h 22m
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United Airlines2h 59m07:59 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center10:58 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from United Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/6/2026 7:59:00 PM to San Antonio Airport, San Antonio Airport (USA) arriving at 6/6/2026 10:58:00 PM. 50 Economy ticket for $153 per person are available. Travel duration is 2h 59m
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Alaska Airlines11h 48m05:52 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center5:40 AMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Alaska Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/6/2026 5:52:00 PM to San Antonio Airport, San Antonio Airport (USA) arriving at 6/7/2026 5:40:00 AM. 50 Economy ticket for $377 per person are available. Travel duration is 11h 48m
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Viva Aerobus8h 45m01:30 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center10:15 AMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Viva Aerobus goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/6/2026 1:30:00 AM to San Antonio Airport, San Antonio Airport (USA) arriving at 6/6/2026 10:15:00 AM. 50 Economy ticket for $524 per person are available. Travel duration is 8h 45m
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Volaris8h 45m07:35 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center4:20 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Volaris goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/6/2026 7:35:00 AM to San Antonio Airport, San Antonio Airport (USA) arriving at 6/6/2026 4:20:00 PM. 50 Economy ticket for $585 per person are available. Travel duration is 8h 45m
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FlixBus35h 25m09:45 AMChicagoDowntown Bus Station9:10 PMSan Antonio, TXPearl District0EconomyA Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 6/6/2026 9:45:00 AM to Pearl District, San Antonio, TX (USA) arriving at 6/7/2026 9:10:00 PM. 50 Economy ticket for $150 per person are available. Travel duration is 35h 25m
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Greyhound US25h 25m010:30 PMChicagoDowntown Bus Station11:55 PMSan Antonio, TXBus Station0EconomyA Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 6/6/2026 10:30:00 PM to Bus Station, San Antonio, TX (USA) arriving at 6/7/2026 11:55:00 PM. 50 Economy ticket for $151 per person are available. Travel duration is 25h 25m
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FlixBus27h 10m09:45 AMChicagoDowntown Bus Station12:55 PMSan Antonio, TXBus Station0EconomyA Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 6/6/2026 9:45:00 AM to Bus Station, San Antonio, TX (USA) arriving at 6/7/2026 12:55:00 PM. 50 Economy ticket for $152 per person are available. Travel duration is 27h 10m
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Greyhound US37h 45m011:10 PMChicagoUnion Station12:55 PMSan Antonio, TXBus Station0EconomyA Bus from Greyhound US goes from Union Station, Chicago (USA) at 6/6/2026 11:10:00 PM to Bus Station, San Antonio, TX (USA) arriving at 6/8/2026 12:55:00 PM. 50 Economy ticket for $156 per person are available. Travel duration is 37h 45m
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Greyhound US48h 35m010:50 PMChicagoDowntown Bus Station11:25 PMSan Antonio, TXPearl District0EconomyA Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 6/6/2026 10:50:00 PM to Pearl District, San Antonio, TX (USA) arriving at 6/8/2026 11:25:00 PM. 50 Economy ticket for $157 per person are available. Travel duration is 48h 35m
Cheapest Flights Saturday
Cheapest Buses Saturday
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FlixBus28h 30m07:25 PMChicago95th Red Line Station11:55 PMSan Antonio, TXBus Station0EconomyA Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 6/7/2026 7:25:00 PM to Bus Station, San Antonio, TX (USA) arriving at 6/8/2026 11:55:00 PM. 50 Economy ticket for $88 per person are available. Travel duration is 28h 30m
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FlixBus37h 5m011:50 PMChicago95th Red Line Station12:55 PMSan Antonio, TXBus Station0EconomyA Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 6/7/2026 11:50:00 PM to Bus Station, San Antonio, TX (USA) arriving at 6/9/2026 12:55:00 PM. 50 Economy ticket for $90 per person are available. Travel duration is 37h 5m
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Greyhound US25h 25m010:30 PMChicagoDowntown Bus Station11:55 PMSan Antonio, TXBus Station0EconomyA Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 6/7/2026 10:30:00 PM to Bus Station, San Antonio, TX (USA) arriving at 6/8/2026 11:55:00 PM. 50 Economy ticket for $103 per person are available. Travel duration is 25h 25m
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Greyhound US47h 40m011:45 PMChicago95th Red Line Station11:25 PMSan Antonio, TXPearl District0EconomyA Bus from Greyhound US goes from 95th Red Line Station, Chicago (USA) at 6/7/2026 11:45:00 PM to Pearl District, San Antonio, TX (USA) arriving at 6/9/2026 11:25:00 PM. 50 Economy ticket for $106 per person are available. Travel duration is 47h 40m
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Tornado Bus Company23h 15m01:30 PMChicagoCalifornia & 35th Street Bus Stop12:45 PMSan Antonio, TXTornado Bus Company0EconomyA Bus from Tornado Bus Company goes from California & 35th Street Bus Stop, Chicago (USA) at 6/7/2026 1:30:00 PM to Tornado Bus Company, San Antonio, TX (USA) arriving at 6/8/2026 12:45:00 PM. 50 Economy ticket for $255 per person are available. Travel duration is 23h 15m
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American Airlines2h 59m09:00 PMChicago Midway AirportChicago Midway Airport11:59 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from American Airlines goes from Chicago Midway Airport, Chicago Midway Airport (USA) at 6/7/2026 9:00:00 PM to San Antonio Airport, San Antonio Airport (USA) arriving at 6/7/2026 11:59:00 PM. 50 Economy ticket for $224 per person are available. Travel duration is 2h 59m
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United Airlines2h 59m07:59 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center10:58 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from United Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/7/2026 7:59:00 PM to San Antonio Airport, San Antonio Airport (USA) arriving at 6/7/2026 10:58:00 PM. 50 Economy ticket for $226 per person are available. Travel duration is 2h 59m
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Sun Country Airlines15h 10m06:39 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center9:49 AMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Sun Country Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/7/2026 6:39:00 PM to San Antonio Airport, San Antonio Airport (USA) arriving at 6/8/2026 9:49:00 AM. 50 Economy ticket for $306 per person are available. Travel duration is 15h 10m
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Frontier Airlines21h 22m09:37 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center6:59 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Frontier Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/7/2026 9:37:00 PM to San Antonio Airport, San Antonio Airport (USA) arriving at 6/8/2026 6:59:00 PM. 50 Economy ticket for $335 per person are available. Travel duration is 21h 22m
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Viva Aerobus8h 45m01:30 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center10:15 AMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Viva Aerobus goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/7/2026 1:30:00 AM to San Antonio Airport, San Antonio Airport (USA) arriving at 6/7/2026 10:15:00 AM. 50 Economy ticket for $408 per person are available. Travel duration is 8h 45m
Cheapest Buses Sunday
Cheapest Flights Sunday
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FlixBus28h 30m07:25 PMChicago95th Red Line Station11:55 PMSan Antonio, TXBus Station0EconomyA Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 6/8/2026 7:25:00 PM to Bus Station, San Antonio, TX (USA) arriving at 6/9/2026 11:55:00 PM. 50 Economy ticket for $110 per person are available. Travel duration is 28h 30m
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FlixBus41h 40m05:45 AMChicago95th Red Line Station11:25 PMSan Antonio, TXPearl District0EconomyA Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 6/8/2026 5:45:00 AM to Pearl District, San Antonio, TX (USA) arriving at 6/9/2026 11:25:00 PM. 50 Economy ticket for $112 per person are available. Travel duration is 41h 40m
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Greyhound US46h 40m010:30 PMChicagoDowntown Bus Station9:10 PMSan Antonio, TXPearl District0EconomyA Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 6/8/2026 10:30:00 PM to Pearl District, San Antonio, TX (USA) arriving at 6/10/2026 9:10:00 PM. 50 Economy ticket for $128 per person are available. Travel duration is 46h 40m
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Greyhound US25h 25m010:30 PMChicagoDowntown Bus Station11:55 PMSan Antonio, TXBus Station0EconomyA Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 6/8/2026 10:30:00 PM to Bus Station, San Antonio, TX (USA) arriving at 6/9/2026 11:55:00 PM. 50 Economy ticket for $129 per person are available. Travel duration is 25h 25m
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Tornado Bus Company23h 15m01:30 PMChicagoCalifornia & 35th Street Bus Stop12:45 PMSan Antonio, TXTornado Bus Company0EconomyA Bus from Tornado Bus Company goes from California & 35th Street Bus Stop, Chicago (USA) at 6/8/2026 1:30:00 PM to Tornado Bus Company, San Antonio, TX (USA) arriving at 6/9/2026 12:45:00 PM. 50 Economy ticket for $255 per person are available. Travel duration is 23h 15m
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Frontier Airlines21h 19m09:37 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center6:56 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Frontier Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/8/2026 9:37:00 PM to San Antonio Airport, San Antonio Airport (USA) arriving at 6/9/2026 6:56:00 PM. 50 Economy ticket for $207 per person are available. Travel duration is 21h 19m
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United Airlines2h 59m07:59 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center10:58 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from United Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/8/2026 7:59:00 PM to San Antonio Airport, San Antonio Airport (USA) arriving at 6/8/2026 10:58:00 PM. 50 Economy ticket for $276 per person are available. Travel duration is 2h 59m
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Viva Aerobus8h 45m01:30 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center10:15 AMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Viva Aerobus goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/8/2026 1:30:00 AM to San Antonio Airport, San Antonio Airport (USA) arriving at 6/8/2026 10:15:00 AM. 50 Economy ticket for $443 per person are available. Travel duration is 8h 45m
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Volaris14h 40m01:40 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center4:20 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Volaris goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/8/2026 1:40:00 AM to San Antonio Airport, San Antonio Airport (USA) arriving at 6/8/2026 4:20:00 PM. 50 Economy ticket for $481 per person are available. Travel duration is 14h 40m
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Alaska Airlines22h 0m07:40 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center5:40 AMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Alaska Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/8/2026 7:40:00 AM to San Antonio Airport, San Antonio Airport (USA) arriving at 6/9/2026 5:40:00 AM. 50 Economy ticket for $502 per person are available. Travel duration is 22h 0m
Cheapest Buses Monday
Cheapest Flights Monday
What are the fastest trips from Chicago to San Antonio, TX?
You can get to San Antonio, TX from Chicago in just 2h 59m with a Flight from American Airlines. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.
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United Airlines3h 2m09:10 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center12:12 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from United Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/2/2026 9:10:00 AM to San Antonio Airport, San Antonio Airport (USA) arriving at 6/2/2026 12:12:00 PM. 50 Economy ticket for $148 per person are available. Travel duration is 3h 2m
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Volaris8h 45m07:35 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center4:20 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Volaris goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/2/2026 7:35:00 AM to San Antonio Airport, San Antonio Airport (USA) arriving at 6/2/2026 4:20:00 PM. 50 Economy ticket for $347 per person are available. Travel duration is 8h 45m
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Viva Aerobus8h 45m01:30 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center10:15 AMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Viva Aerobus goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/2/2026 1:30:00 AM to San Antonio Airport, San Antonio Airport (USA) arriving at 6/2/2026 10:15:00 AM. 50 Economy ticket for $432 per person are available. Travel duration is 8h 45m
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Alaska Airlines11h 56m05:44 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center5:40 AMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Alaska Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/2/2026 5:44:00 PM to San Antonio Airport, San Antonio Airport (USA) arriving at 6/3/2026 5:40:00 AM. 50 Economy ticket for $379 per person are available. Travel duration is 11h 56m
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Frontier Airlines21h 22m09:37 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center6:59 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Frontier Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/2/2026 9:37:00 PM to San Antonio Airport, San Antonio Airport (USA) arriving at 6/3/2026 6:59:00 PM. 50 Economy ticket for $175 per person are available. Travel duration is 21h 22m
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Tornado Bus Company23h 15m01:30 PMChicagoCalifornia & 35th Street Bus Stop12:45 PMSan Antonio, TXTornado Bus Company0BasicA Bus from Tornado Bus Company goes from California & 35th Street Bus Stop, Chicago (USA) at 6/2/2026 1:30:00 PM to Tornado Bus Company, San Antonio, TX (USA) arriving at 6/3/2026 12:45:00 PM. 50 Basic ticket for $255 per person are available. Travel duration is 23h 15m
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Greyhound US25h 25m010:30 PMChicagoDowntown Bus Station11:55 PMSan Antonio, TXBus Station0EconomyA Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 6/2/2026 10:30:00 PM to Bus Station, San Antonio, TX (USA) arriving at 6/3/2026 11:55:00 PM. 50 Economy ticket for $101 per person are available. Travel duration is 25h 25m
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FlixBus31h 10m05:45 AMChicago95th Red Line Station12:55 PMSan Antonio, TXBus Station0EconomyA Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 6/2/2026 5:45:00 AM to Bus Station, San Antonio, TX (USA) arriving at 6/3/2026 12:55:00 PM. 50 Economy ticket for $86 per person are available. Travel duration is 31h 10m
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Greyhound US31h 40m09:55 AMChicagoDowntown Bus Station5:35 PMSan Antonio, TXBus Station0EconomyA Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 6/2/2026 9:55:00 AM to Bus Station, San Antonio, TX (USA) arriving at 6/3/2026 5:35:00 PM. 50 Economy ticket for $102 per person are available. Travel duration is 31h 40m
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FlixBus34h 20m06:40 PMChicago95th Red Line Station5:00 AMSan Antonio, TXBus Station0EconomyA Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 6/2/2026 6:40:00 PM to Bus Station, San Antonio, TX (USA) arriving at 6/4/2026 5:00:00 AM. 50 Economy ticket for $85 per person are available. Travel duration is 34h 20m
Fastest Flights Tuesday
Fastest Buses Tuesday
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United Airlines3h 0m01:30 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center4:30 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from United Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/3/2026 1:30:00 PM to San Antonio Airport, San Antonio Airport (USA) arriving at 6/3/2026 4:30:00 PM. 50 Economy ticket for $147 per person are available. Travel duration is 3h 0m
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Skyscanner3h 13m09:10 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center12:23 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Skyscanner goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/3/2026 9:10:00 AM to San Antonio Airport, San Antonio Airport (USA) arriving at 6/3/2026 12:23:00 PM. 50 Economy ticket for $147 per person are available. Travel duration is 3h 13m
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Volaris8h 45m07:35 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center4:20 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Volaris goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/3/2026 7:35:00 AM to San Antonio Airport, San Antonio Airport (USA) arriving at 6/3/2026 4:20:00 PM. 50 Economy ticket for $353 per person are available. Travel duration is 8h 45m
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Alaska Airlines11h 1m06:00 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center5:01 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Alaska Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/3/2026 6:00:00 AM to San Antonio Airport, San Antonio Airport (USA) arriving at 6/3/2026 5:01:00 PM. 50 Economy ticket for $372 per person are available. Travel duration is 11h 1m
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Frontier Airlines21h 22m09:37 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center6:59 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Frontier Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/3/2026 9:37:00 PM to San Antonio Airport, San Antonio Airport (USA) arriving at 6/4/2026 6:59:00 PM. 50 Economy ticket for $130 per person are available. Travel duration is 21h 22m
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Tornado Bus Company23h 45m01:30 PMChicagoCalifornia & 35th Street Bus Stop1:15 PMSan Antonio, TXTornado Bus Company0BasicA Bus from Tornado Bus Company goes from California & 35th Street Bus Stop, Chicago (USA) at 6/3/2026 1:30:00 PM to Tornado Bus Company, San Antonio, TX (USA) arriving at 6/4/2026 1:15:00 PM. 50 Basic ticket for $255 per person are available. Travel duration is 23h 45m
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Greyhound US25h 25m010:30 PMChicagoDowntown Bus Station11:55 PMSan Antonio, TXBus Station0EconomyA Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 6/3/2026 10:30:00 PM to Bus Station, San Antonio, TX (USA) arriving at 6/4/2026 11:55:00 PM. 50 Economy ticket for $91 per person are available. Travel duration is 25h 25m
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FlixBus28h 30m07:25 PMChicago95th Red Line Station11:55 PMSan Antonio, TXBus Station0EconomyA Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 6/3/2026 7:25:00 PM to Bus Station, San Antonio, TX (USA) arriving at 6/4/2026 11:55:00 PM. 50 Economy ticket for $81 per person are available. Travel duration is 28h 30m
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FlixBus31h 10m05:45 AMChicago95th Red Line Station12:55 PMSan Antonio, TXBus Station0EconomyA Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 6/3/2026 5:45:00 AM to Bus Station, San Antonio, TX (USA) arriving at 6/4/2026 12:55:00 PM. 50 Economy ticket for $81 per person are available. Travel duration is 31h 10m
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Greyhound US45h 25m011:45 PMChicago95th Red Line Station9:10 PMSan Antonio, TXPearl District0EconomyA Bus from Greyhound US goes from 95th Red Line Station, Chicago (USA) at 6/3/2026 11:45:00 PM to Pearl District, San Antonio, TX (USA) arriving at 6/5/2026 9:10:00 PM. 50 Economy ticket for $89 per person are available. Travel duration is 45h 25m
Fastest Flights Wednesday
Fastest Buses Wednesday
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United Airlines3h 2m09:10 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center12:12 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from United Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/4/2026 9:10:00 AM to San Antonio Airport, San Antonio Airport (USA) arriving at 6/4/2026 12:12:00 PM. 50 Economy ticket for $154 per person are available. Travel duration is 3h 2m
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Alaska Airlines11h 56m05:44 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center5:40 AMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Alaska Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/4/2026 5:44:00 PM to San Antonio Airport, San Antonio Airport (USA) arriving at 6/5/2026 5:40:00 AM. 50 Economy ticket for $373 per person are available. Travel duration is 11h 56m
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Volaris14h 40m01:40 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center4:20 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Volaris goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/4/2026 1:40:00 AM to San Antonio Airport, San Antonio Airport (USA) arriving at 6/4/2026 4:20:00 PM. 50 Economy ticket for $352 per person are available. Travel duration is 14h 40m
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Sun Country Airlines15h 16m06:25 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center9:41 AMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Sun Country Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/4/2026 6:25:00 PM to San Antonio Airport, San Antonio Airport (USA) arriving at 6/5/2026 9:41:00 AM. 50 Economy ticket for $193 per person are available. Travel duration is 15h 16m
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Frontier Airlines21h 22m09:37 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center6:59 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Frontier Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/4/2026 9:37:00 PM to San Antonio Airport, San Antonio Airport (USA) arriving at 6/5/2026 6:59:00 PM. 50 Economy ticket for $130 per person are available. Travel duration is 21h 22m
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Greyhound US25h 25m010:30 PMChicagoDowntown Bus Station11:55 PMSan Antonio, TXBus Station0EconomyA Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 6/4/2026 10:30:00 PM to Bus Station, San Antonio, TX (USA) arriving at 6/5/2026 11:55:00 PM. 50 Economy ticket for $133 per person are available. Travel duration is 25h 25m
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FlixBus27h 10m09:45 AMChicagoDowntown Bus Station12:55 PMSan Antonio, TXBus Station0EconomyA Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 6/4/2026 9:45:00 AM to Bus Station, San Antonio, TX (USA) arriving at 6/5/2026 12:55:00 PM. 50 Economy ticket for $131 per person are available. Travel duration is 27h 10m
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Greyhound US31h 20m010:15 AMChicagoUnion Station5:35 PMSan Antonio, TXBus Station0EconomyA Bus from Greyhound US goes from Union Station, Chicago (USA) at 6/4/2026 10:15:00 AM to Bus Station, San Antonio, TX (USA) arriving at 6/5/2026 5:35:00 PM. 50 Economy ticket for $133 per person are available. Travel duration is 31h 20m
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Greyhound US31h 40m09:55 AMChicagoDowntown Bus Station5:35 PMSan Antonio, TXBus Station0EconomyA Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 6/4/2026 9:55:00 AM to Bus Station, San Antonio, TX (USA) arriving at 6/5/2026 5:35:00 PM. 50 Economy ticket for $133 per person are available. Travel duration is 31h 40m
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FlixBus35h 25m09:45 AMChicagoDowntown Bus Station9:10 PMSan Antonio, TXPearl District0EconomyA Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 6/4/2026 9:45:00 AM to Pearl District, San Antonio, TX (USA) arriving at 6/5/2026 9:10:00 PM. 50 Economy ticket for $132 per person are available. Travel duration is 35h 25m
Fastest Flights Thursday
Fastest Buses Thursday
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United Airlines3h 2m09:10 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center12:12 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from United Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/5/2026 9:10:00 AM to San Antonio Airport, San Antonio Airport (USA) arriving at 6/5/2026 12:12:00 PM. 50 Economy ticket for $202 per person are available. Travel duration is 3h 2m
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Volaris8h 45m07:35 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center4:20 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Volaris goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/5/2026 7:35:00 AM to San Antonio Airport, San Antonio Airport (USA) arriving at 6/5/2026 4:20:00 PM. 50 Economy ticket for $338 per person are available. Travel duration is 8h 45m
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Viva Aerobus8h 45m01:30 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center10:15 AMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Viva Aerobus goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/5/2026 1:30:00 AM to San Antonio Airport, San Antonio Airport (USA) arriving at 6/5/2026 10:15:00 AM. 50 Economy ticket for $504 per person are available. Travel duration is 8h 45m
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Alaska Airlines11h 56m05:44 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center5:40 AMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Alaska Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/5/2026 5:44:00 PM to San Antonio Airport, San Antonio Airport (USA) arriving at 6/6/2026 5:40:00 AM. 50 Economy ticket for $373 per person are available. Travel duration is 11h 56m
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Frontier Airlines21h 22m09:37 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center6:59 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Frontier Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/5/2026 9:37:00 PM to San Antonio Airport, San Antonio Airport (USA) arriving at 6/6/2026 6:59:00 PM. 50 Economy ticket for $130 per person are available. Travel duration is 21h 22m
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Tornado Bus Company23h 30m01:30 PMChicagoCalifornia & 35th Street Bus Stop1:00 PMSan Antonio, TXTornado Bus Company0EconomyA Bus from Tornado Bus Company goes from California & 35th Street Bus Stop, Chicago (USA) at 6/5/2026 1:30:00 PM to Tornado Bus Company, San Antonio, TX (USA) arriving at 6/6/2026 1:00:00 PM. 50 Economy ticket for $255 per person are available. Travel duration is 23h 30m
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Greyhound US25h 25m010:30 PMChicagoDowntown Bus Station11:55 PMSan Antonio, TXBus Station0EconomyA Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 6/5/2026 10:30:00 PM to Bus Station, San Antonio, TX (USA) arriving at 6/6/2026 11:55:00 PM. 50 Economy ticket for $118 per person are available. Travel duration is 25h 25m
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FlixBus28h 30m07:25 PMChicago95th Red Line Station11:55 PMSan Antonio, TXBus Station0EconomyA Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 6/5/2026 7:25:00 PM to Bus Station, San Antonio, TX (USA) arriving at 6/6/2026 11:55:00 PM. 50 Economy ticket for $94 per person are available. Travel duration is 28h 30m
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FlixBus31h 10m05:45 AMChicago95th Red Line Station12:55 PMSan Antonio, TXBus Station0EconomyA Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 6/5/2026 5:45:00 AM to Bus Station, San Antonio, TX (USA) arriving at 6/6/2026 12:55:00 PM. 50 Economy ticket for $97 per person are available. Travel duration is 31h 10m
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Greyhound US45h 25m011:45 PMChicago95th Red Line Station9:10 PMSan Antonio, TXPearl District0EconomyA Bus from Greyhound US goes from 95th Red Line Station, Chicago (USA) at 6/5/2026 11:45:00 PM to Pearl District, San Antonio, TX (USA) arriving at 6/7/2026 9:10:00 PM. 50 Economy ticket for $106 per person are available. Travel duration is 45h 25m
Fastest Flights Friday
Fastest Buses Friday
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United Airlines2h 59m07:59 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center10:58 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from United Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/6/2026 7:59:00 PM to San Antonio Airport, San Antonio Airport (USA) arriving at 6/6/2026 10:58:00 PM. 50 Economy ticket for $153 per person are available. Travel duration is 2h 59m
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Viva Aerobus8h 45m01:30 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center10:15 AMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Viva Aerobus goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/6/2026 1:30:00 AM to San Antonio Airport, San Antonio Airport (USA) arriving at 6/6/2026 10:15:00 AM. 50 Economy ticket for $524 per person are available. Travel duration is 8h 45m
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Volaris8h 45m07:35 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center4:20 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Volaris goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/6/2026 7:35:00 AM to San Antonio Airport, San Antonio Airport (USA) arriving at 6/6/2026 4:20:00 PM. 50 Economy ticket for $585 per person are available. Travel duration is 8h 45m
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Alaska Airlines11h 48m05:52 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center5:40 AMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Alaska Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/6/2026 5:52:00 PM to San Antonio Airport, San Antonio Airport (USA) arriving at 6/7/2026 5:40:00 AM. 50 Economy ticket for $377 per person are available. Travel duration is 11h 48m
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Frontier Airlines21h 22m09:37 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center6:59 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Frontier Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/6/2026 9:37:00 PM to San Antonio Airport, San Antonio Airport (USA) arriving at 6/7/2026 6:59:00 PM. 50 Economy ticket for $129 per person are available. Travel duration is 21h 22m
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Greyhound US25h 25m010:30 PMChicagoDowntown Bus Station11:55 PMSan Antonio, TXBus Station0EconomyA Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 6/6/2026 10:30:00 PM to Bus Station, San Antonio, TX (USA) arriving at 6/7/2026 11:55:00 PM. 50 Economy ticket for $151 per person are available. Travel duration is 25h 25m
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FlixBus27h 10m09:45 AMChicagoDowntown Bus Station12:55 PMSan Antonio, TXBus Station0EconomyA Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 6/6/2026 9:45:00 AM to Bus Station, San Antonio, TX (USA) arriving at 6/7/2026 12:55:00 PM. 50 Economy ticket for $152 per person are available. Travel duration is 27h 10m
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FlixBus35h 25m09:45 AMChicagoDowntown Bus Station9:10 PMSan Antonio, TXPearl District0EconomyA Bus from FlixBus goes from Downtown Bus Station, Chicago (USA) at 6/6/2026 9:45:00 AM to Pearl District, San Antonio, TX (USA) arriving at 6/7/2026 9:10:00 PM. 50 Economy ticket for $150 per person are available. Travel duration is 35h 25m
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Greyhound US37h 45m011:10 PMChicagoUnion Station12:55 PMSan Antonio, TXBus Station0EconomyA Bus from Greyhound US goes from Union Station, Chicago (USA) at 6/6/2026 11:10:00 PM to Bus Station, San Antonio, TX (USA) arriving at 6/8/2026 12:55:00 PM. 50 Economy ticket for $156 per person are available. Travel duration is 37h 45m
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Greyhound US48h 35m010:50 PMChicagoDowntown Bus Station11:25 PMSan Antonio, TXPearl District0EconomyA Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 6/6/2026 10:50:00 PM to Pearl District, San Antonio, TX (USA) arriving at 6/8/2026 11:25:00 PM. 50 Economy ticket for $157 per person are available. Travel duration is 48h 35m
Fastest Flights Saturday
Fastest Buses Saturday
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American Airlines2h 59m09:00 PMChicago Midway AirportChicago Midway Airport11:59 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from American Airlines goes from Chicago Midway Airport, Chicago Midway Airport (USA) at 6/7/2026 9:00:00 PM to San Antonio Airport, San Antonio Airport (USA) arriving at 6/7/2026 11:59:00 PM. 50 Economy ticket for $224 per person are available. Travel duration is 2h 59m
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United Airlines2h 59m07:59 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center10:58 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from United Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/7/2026 7:59:00 PM to San Antonio Airport, San Antonio Airport (USA) arriving at 6/7/2026 10:58:00 PM. 50 Economy ticket for $226 per person are available. Travel duration is 2h 59m
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Viva Aerobus8h 45m01:30 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center10:15 AMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Viva Aerobus goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/7/2026 1:30:00 AM to San Antonio Airport, San Antonio Airport (USA) arriving at 6/7/2026 10:15:00 AM. 50 Economy ticket for $408 per person are available. Travel duration is 8h 45m
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Sun Country Airlines15h 10m06:39 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center9:49 AMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Sun Country Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/7/2026 6:39:00 PM to San Antonio Airport, San Antonio Airport (USA) arriving at 6/8/2026 9:49:00 AM. 50 Economy ticket for $306 per person are available. Travel duration is 15h 10m
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Frontier Airlines21h 22m09:37 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center6:59 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Frontier Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/7/2026 9:37:00 PM to San Antonio Airport, San Antonio Airport (USA) arriving at 6/8/2026 6:59:00 PM. 50 Economy ticket for $335 per person are available. Travel duration is 21h 22m
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Tornado Bus Company23h 15m01:30 PMChicagoCalifornia & 35th Street Bus Stop12:45 PMSan Antonio, TXTornado Bus Company0EconomyA Bus from Tornado Bus Company goes from California & 35th Street Bus Stop, Chicago (USA) at 6/7/2026 1:30:00 PM to Tornado Bus Company, San Antonio, TX (USA) arriving at 6/8/2026 12:45:00 PM. 50 Economy ticket for $255 per person are available. Travel duration is 23h 15m
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Greyhound US25h 25m010:30 PMChicagoDowntown Bus Station11:55 PMSan Antonio, TXBus Station0EconomyA Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 6/7/2026 10:30:00 PM to Bus Station, San Antonio, TX (USA) arriving at 6/8/2026 11:55:00 PM. 50 Economy ticket for $103 per person are available. Travel duration is 25h 25m
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FlixBus28h 30m07:25 PMChicago95th Red Line Station11:55 PMSan Antonio, TXBus Station0EconomyA Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 6/7/2026 7:25:00 PM to Bus Station, San Antonio, TX (USA) arriving at 6/8/2026 11:55:00 PM. 50 Economy ticket for $88 per person are available. Travel duration is 28h 30m
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FlixBus37h 5m011:50 PMChicago95th Red Line Station12:55 PMSan Antonio, TXBus Station0EconomyA Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 6/7/2026 11:50:00 PM to Bus Station, San Antonio, TX (USA) arriving at 6/9/2026 12:55:00 PM. 50 Economy ticket for $90 per person are available. Travel duration is 37h 5m
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Greyhound US47h 40m011:45 PMChicago95th Red Line Station11:25 PMSan Antonio, TXPearl District0EconomyA Bus from Greyhound US goes from 95th Red Line Station, Chicago (USA) at 6/7/2026 11:45:00 PM to Pearl District, San Antonio, TX (USA) arriving at 6/9/2026 11:25:00 PM. 50 Economy ticket for $106 per person are available. Travel duration is 47h 40m
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United Airlines2h 59m07:59 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center10:58 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from United Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/8/2026 7:59:00 PM to San Antonio Airport, San Antonio Airport (USA) arriving at 6/8/2026 10:58:00 PM. 50 Economy ticket for $276 per person are available. Travel duration is 2h 59m
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Viva Aerobus8h 45m01:30 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center10:15 AMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Viva Aerobus goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/8/2026 1:30:00 AM to San Antonio Airport, San Antonio Airport (USA) arriving at 6/8/2026 10:15:00 AM. 50 Economy ticket for $443 per person are available. Travel duration is 8h 45m
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Volaris14h 40m01:40 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center4:20 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Volaris goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/8/2026 1:40:00 AM to San Antonio Airport, San Antonio Airport (USA) arriving at 6/8/2026 4:20:00 PM. 50 Economy ticket for $481 per person are available. Travel duration is 14h 40m
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Frontier Airlines21h 19m09:37 PMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center6:56 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Frontier Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/8/2026 9:37:00 PM to San Antonio Airport, San Antonio Airport (USA) arriving at 6/9/2026 6:56:00 PM. 50 Economy ticket for $207 per person are available. Travel duration is 21h 19m
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Alaska Airlines22h 0m07:40 AMChicago O'Hare AirportChicago O'Hare Airport - Bus/Shuttle Center5:40 AMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Alaska Airlines goes from Chicago O'Hare Airport - Bus/Shuttle Center, Chicago O'Hare Airport (USA) at 6/8/2026 7:40:00 AM to San Antonio Airport, San Antonio Airport (USA) arriving at 6/9/2026 5:40:00 AM. 50 Economy ticket for $502 per person are available. Travel duration is 22h 0m
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Tornado Bus Company23h 15m01:30 PMChicagoCalifornia & 35th Street Bus Stop12:45 PMSan Antonio, TXTornado Bus Company0EconomyA Bus from Tornado Bus Company goes from California & 35th Street Bus Stop, Chicago (USA) at 6/8/2026 1:30:00 PM to Tornado Bus Company, San Antonio, TX (USA) arriving at 6/9/2026 12:45:00 PM. 50 Economy ticket for $255 per person are available. Travel duration is 23h 15m
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Greyhound US25h 25m010:30 PMChicagoDowntown Bus Station11:55 PMSan Antonio, TXBus Station0EconomyA Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 6/8/2026 10:30:00 PM to Bus Station, San Antonio, TX (USA) arriving at 6/9/2026 11:55:00 PM. 50 Economy ticket for $129 per person are available. Travel duration is 25h 25m
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FlixBus28h 30m07:25 PMChicago95th Red Line Station11:55 PMSan Antonio, TXBus Station0EconomyA Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 6/8/2026 7:25:00 PM to Bus Station, San Antonio, TX (USA) arriving at 6/9/2026 11:55:00 PM. 50 Economy ticket for $110 per person are available. Travel duration is 28h 30m
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FlixBus41h 40m05:45 AMChicago95th Red Line Station11:25 PMSan Antonio, TXPearl District0EconomyA Bus from FlixBus goes from 95th Red Line Station, Chicago (USA) at 6/8/2026 5:45:00 AM to Pearl District, San Antonio, TX (USA) arriving at 6/9/2026 11:25:00 PM. 50 Economy ticket for $112 per person are available. Travel duration is 41h 40m
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Greyhound US46h 40m010:30 PMChicagoDowntown Bus Station9:10 PMSan Antonio, TXPearl District0EconomyA Bus from Greyhound US goes from Downtown Bus Station, Chicago (USA) at 6/8/2026 10:30:00 PM to Pearl District, San Antonio, TX (USA) arriving at 6/10/2026 9:10:00 PM. 50 Economy ticket for $128 per person are available. Travel duration is 46h 40m
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Here you will find all operators and timetables for a
Bus from Chicago to San Antonio, TX
What are the most popular stations in Chicago and San Antonio, TX?
In Chicago, you will usually depart from California & 35th Street Bus Stop, Downtown Bus Station or 95th Red Line Station, while in San Antonio, TX you will be arriving at Tornado Bus Company, Bus Station or W. Southcross & Buffalo Bus Stop, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to San Antonio, TX from Chicago? With 10 connections between 3 Flight and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Chicago and San Antonio, TX, you can pay as low as $81 with a Bus from FlixBus.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from American Airlines: you will get to San Antonio, TX in just 2h 59m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Chicago and San Antonio, TX are Greyhound US, FlixBus and United Airlines, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in Chicago and San Antonio, TX is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Cicero, IL or to Olmos Park, TX, and look at flights from Chicago Midway Airport, and landing at San Antonio Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from Chicago to San Antonio, TX?
The most popular companies between Chicago and San Antonio, TX, are Greyhound US, FlixBus and United Airlines. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: Greyhound US, FlixBus and Tornado Bus Company
Airlines: United Airlines, Frontier Airlines, Volaris and 5 more.
All you need to know when you travel from Chicago to San Antonio, TX
Check all information on comfort and services on all modes of transports from Chicago to San Antonio, TX. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from Chicago to San Antonio, TX
How can I reach San Antonio, TX from Chicago?
Every day, there are on average 10 connections between Flight and Bus, with which you can get to San Antonio, TX from Chicago.
How far is San Antonio, TX from Chicago?
The distance between Chicago and San Antonio, TX is 1,052.2 miles.
What is the most ecofriendly mode of transport between Chicago and San Antonio, TX?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 46 kgs of CO2, a train 59 kgs, a car 288 kgs, and a flight 417 kgs.
What is the cheapest mode of transport from Chicago to San Antonio, TX?
You can get to San Antonio, TX with just $81 by taking a Bus from FlixBus.
What is the fastest way to get from Chicago to San Antonio, TX?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to San Antonio, TX in just 2h 59m with a Flight from American Airlines.
More routes to Chicago and to San Antonio, TX
Looking for more options? Here you can see the most popular routes to Chicago and to San Antonio, TX. Simply click on a connection, and you’ll find all the details about the route!
