How to get from St. Louis, MO to San Antonio, TX

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What is the best way to travel from St. Louis, MO to San Antonio, TX?

Looking for a trip? Compare all the available Flights and Buses for the journey to San Antonio, TX from St. Louis, MO. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 2 available companies to find your perfect trip!
Bus is the cheapest and fastest way on this route
Transport type
Travel time
Cheapest price
Average price
Daily departures
Bus
20h 5m
$114
$156
10

What is the cheapest way to reach San Antonio, TX from St. Louis, MO?

You can get to San Antonio, TX with just $114 by taking a Bus from Greyhound US, but you can find many more cheap offers: we have selected the best ones for next few days here for you.

Friday
from $240
Saturday
from $177
Sunday
from $147
Monday
from $140
Tuesday
from $114
Wednesday
Thursday
from $123

    Cheapest Buses Friday

  • Greyhound US
    22h 35m
    0
    1:20 AM
    St. Louis, MO
    Gateway Station
    11:55 PM
    San Antonio, TX
    Bus Station
    0
    Greyhound US
    Economy
    $240
  • Greyhound US
    23h 45m
    0
    1:30 AM
    St. Louis, MO
    Gateway Station
    1:15 AM
    San Antonio, TX
    Bus Station
    0
    Greyhound US
    Economy
    $240
  • FlixBus
    20h 55m
    0
    4:00 PM
    St. Louis, MO
    Gateway Station
    12:55 PM
    San Antonio, TX
    Bus Station
    0
    FlixBus
    Economy
    $241

    Cheapest Buses Saturday

  • Greyhound US
    23h 45m
    0
    1:30 AM
    St. Louis, MO
    Gateway Station
    1:15 AM
    San Antonio, TX
    Bus Station
    0
    Greyhound US
    Economy
    $177
  • Greyhound US
    25h 35m
    0
    4:30 PM
    St. Louis, MO
    Gateway Station
    7:05 PM
    San Antonio, TX
    Bus Station
    0
    Greyhound US
    Economy
    $179
  • FlixBus
    20h 5m
    0
    4:00 PM
    St. Louis, MO
    Gateway Station
    1:05 PM
    San Antonio, TX
    Bus Station
    0
    FlixBus
    Economy
    $180
  • Greyhound US
    22h 35m
    0
    1:20 AM
    St. Louis, MO
    Gateway Station
    11:55 PM
    San Antonio, TX
    Bus Station
    0
    Greyhound US
    Economy
    $181

    Cheapest Buses Sunday

  • Greyhound US
    22h 45m
    0
    1:30 AM
    St. Louis, MO
    Gateway Station
    1:15 AM
    San Antonio, TX
    Bus Station
    0
    Greyhound US
    Economy
    $147
  • Greyhound US
    25h 5m
    0
    4:30 PM
    St. Louis, MO
    Gateway Station
    5:35 PM
    San Antonio, TX
    Bus Station
    0
    Greyhound US
    Economy
    $149
  • Greyhound US
    30h 55m
    0
    4:30 PM
    St. Louis, MO
    Gateway Station
    11:25 PM
    San Antonio, TX
    Pearl District
    0
    Greyhound US
    Economy
    $149
  • FlixBus
    20h 55m
    0
    4:00 PM
    St. Louis, MO
    Gateway Station
    12:55 PM
    San Antonio, TX
    Bus Station
    0
    FlixBus
    Economy
    $149

    Cheapest Buses Monday

  • Greyhound US
    22h 35m
    0
    1:20 AM
    St. Louis, MO
    Gateway Station
    11:55 PM
    San Antonio, TX
    Bus Station
    0
    Greyhound US
    Economy
    $140
  • Greyhound US
    25h 5m
    0
    4:30 PM
    St. Louis, MO
    Gateway Station
    5:35 PM
    San Antonio, TX
    Bus Station
    0
    Greyhound US
    Economy
    $140
  • Greyhound US
    30h 55m
    0
    4:30 PM
    St. Louis, MO
    Gateway Station
    11:25 PM
    San Antonio, TX
    Pearl District
    0
    Greyhound US
    Economy
    $140
  • FlixBus
    20h 55m
    0
    4:00 PM
    St. Louis, MO
    Gateway Station
    12:55 PM
    San Antonio, TX
    Bus Station
    0
    FlixBus
    Economy
    $142

    Cheapest Buses Tuesday

  • Greyhound US
    25h 5m
    0
    4:30 PM
    St. Louis, MO
    Gateway Station
    5:35 PM
    San Antonio, TX
    Bus Station
    0
    Greyhound US
    Economy
    $114
  • Greyhound US
    22h 35m
    0
    1:20 AM
    St. Louis, MO
    Gateway Station
    11:55 PM
    San Antonio, TX
    Bus Station
    0
    Greyhound US
    Economy
    $115
  • Greyhound US
    23h 45m
    0
    1:30 AM
    St. Louis, MO
    Gateway Station
    1:15 AM
    San Antonio, TX
    Bus Station
    0
    Greyhound US
    Economy
    $115

    Cheapest Buses Thursday

  • Greyhound US
    23h 45m
    0
    1:30 AM
    St. Louis, MO
    Gateway Station
    1:15 AM
    San Antonio, TX
    Bus Station
    0
    Greyhound US
    Economy
    $123
  • Greyhound US
    25h 5m
    0
    4:30 PM
    St. Louis, MO
    Gateway Station
    5:35 PM
    San Antonio, TX
    Bus Station
    0
    Greyhound US
    Economy
    $124
  • Greyhound US
    22h 35m
    0
    1:20 AM
    St. Louis, MO
    Gateway Station
    11:55 PM
    San Antonio, TX
    Bus Station
    0
    Greyhound US
    Economy
    $125
  • FlixBus
    20h 55m
    0
    4:00 PM
    St. Louis, MO
    Gateway Station
    12:55 PM
    San Antonio, TX
    Bus Station
    0
    FlixBus
    Economy
    $125

What are the fastest trips from St. Louis, MO to San Antonio, TX?

You can get to San Antonio, TX from St. Louis, MO in just 20h 5m with a Bus from FlixBus. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.

Friday
from 20h 55m
Saturday
from 20h 5m
Sunday
from 20h 55m
Monday
from 20h 55m
Tuesday
from 22h 35m
Wednesday
Thursday
from 20h 55m

    Fastest Buses Friday

  • FlixBus
    20h 55m
    0
    4:00 PM
    St. Louis, MO
    Gateway Station
    12:55 PM
    San Antonio, TX
    Bus Station
    0
    FlixBus
    Economy
    $241
  • Greyhound US
    22h 35m
    0
    1:20 AM
    St. Louis, MO
    Gateway Station
    11:55 PM
    San Antonio, TX
    Bus Station
    0
    Greyhound US
    Economy
    $240
  • Greyhound US
    23h 45m
    0
    1:30 AM
    St. Louis, MO
    Gateway Station
    1:15 AM
    San Antonio, TX
    Bus Station
    0
    Greyhound US
    Economy
    $240

    Fastest Buses Saturday

  • FlixBus
    20h 5m
    0
    4:00 PM
    St. Louis, MO
    Gateway Station
    1:05 PM
    San Antonio, TX
    Bus Station
    0
    FlixBus
    Economy
    $180
  • Greyhound US
    22h 35m
    0
    1:20 AM
    St. Louis, MO
    Gateway Station
    11:55 PM
    San Antonio, TX
    Bus Station
    0
    Greyhound US
    Economy
    $181
  • Greyhound US
    23h 45m
    0
    1:30 AM
    St. Louis, MO
    Gateway Station
    1:15 AM
    San Antonio, TX
    Bus Station
    0
    Greyhound US
    Economy
    $177
  • Greyhound US
    25h 35m
    0
    4:30 PM
    St. Louis, MO
    Gateway Station
    7:05 PM
    San Antonio, TX
    Bus Station
    0
    Greyhound US
    Economy
    $179

    Fastest Buses Sunday

  • FlixBus
    20h 55m
    0
    4:00 PM
    St. Louis, MO
    Gateway Station
    12:55 PM
    San Antonio, TX
    Bus Station
    0
    FlixBus
    Economy
    $149
  • Greyhound US
    22h 45m
    0
    1:30 AM
    St. Louis, MO
    Gateway Station
    1:15 AM
    San Antonio, TX
    Bus Station
    0
    Greyhound US
    Economy
    $147
  • Greyhound US
    25h 5m
    0
    4:30 PM
    St. Louis, MO
    Gateway Station
    5:35 PM
    San Antonio, TX
    Bus Station
    0
    Greyhound US
    Economy
    $149
  • Greyhound US
    30h 55m
    0
    4:30 PM
    St. Louis, MO
    Gateway Station
    11:25 PM
    San Antonio, TX
    Pearl District
    0
    Greyhound US
    Economy
    $149

    Fastest Buses Monday

  • FlixBus
    20h 55m
    0
    4:00 PM
    St. Louis, MO
    Gateway Station
    12:55 PM
    San Antonio, TX
    Bus Station
    0
    FlixBus
    Economy
    $142
  • Greyhound US
    22h 35m
    0
    1:20 AM
    St. Louis, MO
    Gateway Station
    11:55 PM
    San Antonio, TX
    Bus Station
    0
    Greyhound US
    Economy
    $140
  • Greyhound US
    25h 5m
    0
    4:30 PM
    St. Louis, MO
    Gateway Station
    5:35 PM
    San Antonio, TX
    Bus Station
    0
    Greyhound US
    Economy
    $140
  • Greyhound US
    30h 55m
    0
    4:30 PM
    St. Louis, MO
    Gateway Station
    11:25 PM
    San Antonio, TX
    Pearl District
    0
    Greyhound US
    Economy
    $140

    Fastest Buses Tuesday

  • Greyhound US
    22h 35m
    0
    1:20 AM
    St. Louis, MO
    Gateway Station
    11:55 PM
    San Antonio, TX
    Bus Station
    0
    Greyhound US
    Economy
    $115
  • Greyhound US
    23h 45m
    0
    1:30 AM
    St. Louis, MO
    Gateway Station
    1:15 AM
    San Antonio, TX
    Bus Station
    0
    Greyhound US
    Economy
    $115
  • Greyhound US
    25h 5m
    0
    4:30 PM
    St. Louis, MO
    Gateway Station
    5:35 PM
    San Antonio, TX
    Bus Station
    0
    Greyhound US
    Economy
    $114

    Fastest Buses Thursday

  • FlixBus
    20h 55m
    0
    4:00 PM
    St. Louis, MO
    Gateway Station
    12:55 PM
    San Antonio, TX
    Bus Station
    0
    FlixBus
    Economy
    $125
  • Greyhound US
    22h 35m
    0
    1:20 AM
    St. Louis, MO
    Gateway Station
    11:55 PM
    San Antonio, TX
    Bus Station
    0
    Greyhound US
    Economy
    $125
  • Greyhound US
    23h 45m
    0
    1:30 AM
    St. Louis, MO
    Gateway Station
    1:15 AM
    San Antonio, TX
    Bus Station
    0
    Greyhound US
    Economy
    $123
  • Greyhound US
    25h 5m
    0
    4:30 PM
    St. Louis, MO
    Gateway Station
    5:35 PM
    San Antonio, TX
    Bus Station
    0
    Greyhound US
    Economy
    $124
Here you will find all operators and timetables for a Bus from St. Louis, MO to San Antonio, TX

What are the most popular stations in St. Louis, MO and San Antonio, TX?

In St. Louis, MO, you will usually depart from Gateway Station, Lindbergh @ Hackberry NB Bus Stop or Skinker Boulevard, while in San Antonio, TX you will be arriving at Tornado Bus Company, Bus Station or W. Southcross & Buffalo Bus Stop, but there are many more stops to explore in both locations.

How do I decide? Some tips and tricks from our experience

Are you having trouble deciding on how to get to San Antonio, TX from St. Louis, MO? With 5 connections between 2 Flight and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.

Look for the lowest price

Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between St. Louis, MO and San Antonio, TX, you can pay as low as $114 with a Bus from Greyhound US.

Travel duration

Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Bus from FlixBus: you will get to San Antonio, TX in just 20h 5m.

Comfort makes all the difference

You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting St. Louis, MO and San Antonio, TX are Greyhound US and FlixBus, but be sure to check what they have to offer!

Save money with deals, and always compare

One last tip? Even if you live in St. Louis, MO and San Antonio, TX is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Sauget, IL or to Olmos Park, TX, and look at flights from St. Louis Lambert Airport, and landing at San Antonio Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!

Which companies offer a trip from St. Louis, MO to San Antonio, TX?

The most popular companies between St. Louis, MO and San Antonio, TX, are Greyhound US and FlixBus. Be sure to check their seat class offers and the amenities that they provide.

Bus companies: Greyhound US and FlixBus

All you need to know when you travel from St. Louis, MO to San Antonio, TX

Check all information on comfort and services on all modes of transports from St. Louis, MO to San Antonio, TX. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.

FAQs about the trip from St. Louis, MO to San Antonio, TX

How can I reach San Antonio, TX from St. Louis, MO?

Every day, there are on average 5 connections between Flight and Bus, with which you can get to San Antonio, TX from St. Louis, MO.

How far is San Antonio, TX from St. Louis, MO?

The distance between St. Louis, MO and San Antonio, TX is 792.3 miles.

What is the most ecofriendly mode of transport between St. Louis, MO and San Antonio, TX?

Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance. On this particular route, a bus will emit, per person, a total of 34 kgs of CO2, a train 45 kgs, a car 217 kgs, and a flight 314 kgs.

What is the cheapest mode of transport from St. Louis, MO to San Antonio, TX?

You can get to San Antonio, TX with just $114 by taking a Bus from Greyhound US.

What is the fastest way to get from St. Louis, MO to San Antonio, TX?

While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to San Antonio, TX in just 20h 5m with a Bus from FlixBus.

More routes to St. Louis, MO and to San Antonio, TX

Looking for more options? Here you can see the most popular routes to St. Louis, MO and to San Antonio, TX. Simply click on a connection, and you’ll find all the details about the route!

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