What is the best way to travel from St. Louis, MO to San Antonio, TX?
Looking for a trip? Compare all the available Flights and Buses for the journey to San Antonio, TX from St. Louis, MO. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 2 available companies to find your perfect trip!
What is the cheapest way to reach San Antonio, TX from St. Louis, MO?
You can get to San Antonio, TX with just $76 by taking a Flight from Frontier Airlines, but you can find many more cheap offers: we have selected the best ones for next few days here for you.
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Greyhound US25h 5m04:30 PMSt. Louis, MOGateway Station5:35 PMSan Antonio, TXBus Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 4/20/2026 4:30:00 PM to Bus Station, San Antonio, TX (USA) arriving at 4/21/2026 5:35:00 PM. 50 Economy ticket for $105 per person are available. Travel duration is 25h 5m
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Greyhound US30h 55m04:30 PMSt. Louis, MOGateway Station11:25 PMSan Antonio, TXPearl District0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 4/20/2026 4:30:00 PM to Pearl District, San Antonio, TX (USA) arriving at 4/21/2026 11:25:00 PM. 50 Economy ticket for $106 per person are available. Travel duration is 30h 55m
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FlixBus20h 55m04:00 PMSt. Louis, MOGateway Station12:55 PMSan Antonio, TXBus Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 4/20/2026 4:00:00 PM to Bus Station, San Antonio, TX (USA) arriving at 4/21/2026 12:55:00 PM. 50 Economy ticket for $107 per person are available. Travel duration is 20h 55m
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Greyhound US22h 35m01:20 AMSt. Louis, MOGateway Station11:55 PMSan Antonio, TXBus Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 4/20/2026 1:20:00 AM to Bus Station, San Antonio, TX (USA) arriving at 4/20/2026 11:55:00 PM. 50 Economy ticket for $108 per person are available. Travel duration is 22h 35m
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Frontier Airlines18h 52m08:17 PMSt. Louis Lambert AirportSt. Louis Lambert Airport3:09 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 4/20/2026 8:17:00 PM to San Antonio Airport, San Antonio Airport (USA) arriving at 4/21/2026 3:09:00 PM. 50 Economy ticket for $115 per person are available. Travel duration is 18h 52m
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United Airlines7h 8m06:00 AMSt. Louis Lambert AirportSt. Louis Lambert Airport1:08 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 4/20/2026 6:00:00 AM to San Antonio Airport, San Antonio Airport (USA) arriving at 4/20/2026 1:08:00 PM. 50 Economy ticket for $194 per person are available. Travel duration is 7h 8m
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United Airlines6h 2m02:40 PMSt. Louis Lambert AirportSt. Louis Lambert Airport8:42 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 4/20/2026 2:40:00 PM to San Antonio Airport, San Antonio Airport (USA) arriving at 4/20/2026 8:42:00 PM. 50 Economy ticket for $196 per person are available. Travel duration is 6h 2m
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Alaska Airlines9h 54m07:00 AMSt. Louis Lambert AirportSt. Louis Lambert Airport4:54 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Alaska Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 4/20/2026 7:00:00 AM to San Antonio Airport, San Antonio Airport (USA) arriving at 4/20/2026 4:54:00 PM. 50 Economy ticket for $424 per person are available. Travel duration is 9h 54m
Cheapest Buses Monday
Cheapest Flights Monday
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United Airlines4h 50m06:00 AMSt. Louis Lambert AirportSt. Louis Lambert Airport10:50 AMSan Antonio AirportSan Antonio Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 4/21/2026 6:00:00 AM to San Antonio Airport, San Antonio Airport (USA) arriving at 4/21/2026 10:50:00 AM. 50 Economy ticket for $143 per person are available. Travel duration is 4h 50m
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United Airlines8h 2m08:54 AMSt. Louis Lambert AirportSt. Louis Lambert Airport4:56 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 4/21/2026 8:54:00 AM to San Antonio Airport, San Antonio Airport (USA) arriving at 4/21/2026 4:56:00 PM. 50 Economy ticket for $168 per person are available. Travel duration is 8h 2m
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Frontier Airlines20h 18m04:59 PMSt. Louis Lambert AirportSt. Louis Lambert Airport1:17 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 4/21/2026 4:59:00 PM to San Antonio Airport, San Antonio Airport (USA) arriving at 4/22/2026 1:17:00 PM. 50 Economy ticket for $226 per person are available. Travel duration is 20h 18m
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Alaska Airlines9h 54m07:00 AMSt. Louis Lambert AirportSt. Louis Lambert Airport4:54 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Alaska Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 4/21/2026 7:00:00 AM to San Antonio Airport, San Antonio Airport (USA) arriving at 4/21/2026 4:54:00 PM. 50 Economy ticket for $420 per person are available. Travel duration is 9h 54m
Cheapest Flights Tuesday
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Greyhound US23h 45m01:30 AMSt. Louis, MOGateway Station1:15 AMSan Antonio, TXBus Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 4/22/2026 1:30:00 AM to Bus Station, San Antonio, TX (USA) arriving at 4/23/2026 1:15:00 AM. 50 Economy ticket for $119 per person are available. Travel duration is 23h 45m
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Greyhound US25h 5m04:30 PMSt. Louis, MOGateway Station5:35 PMSan Antonio, TXBus Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 4/22/2026 4:30:00 PM to Bus Station, San Antonio, TX (USA) arriving at 4/23/2026 5:35:00 PM. 50 Economy ticket for $119 per person are available. Travel duration is 25h 5m
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Greyhound US22h 35m01:20 AMSt. Louis, MOGateway Station11:55 PMSan Antonio, TXBus Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 4/22/2026 1:20:00 AM to Bus Station, San Antonio, TX (USA) arriving at 4/22/2026 11:55:00 PM. 50 Economy ticket for $120 per person are available. Travel duration is 22h 35m
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United Airlines4h 50m06:00 AMSt. Louis Lambert AirportSt. Louis Lambert Airport10:50 AMSan Antonio AirportSan Antonio Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 4/22/2026 6:00:00 AM to San Antonio Airport, San Antonio Airport (USA) arriving at 4/22/2026 10:50:00 AM. 50 Economy ticket for $142 per person are available. Travel duration is 4h 50m
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United Airlines8h 2m08:54 AMSt. Louis Lambert AirportSt. Louis Lambert Airport4:56 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 4/22/2026 8:54:00 AM to San Antonio Airport, San Antonio Airport (USA) arriving at 4/22/2026 4:56:00 PM. 50 Economy ticket for $147 per person are available. Travel duration is 8h 2m
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Frontier Airlines20h 18m04:59 PMSt. Louis Lambert AirportSt. Louis Lambert Airport1:17 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 4/22/2026 4:59:00 PM to San Antonio Airport, San Antonio Airport (USA) arriving at 4/23/2026 1:17:00 PM. 50 Economy ticket for $217 per person are available. Travel duration is 20h 18m
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Skyscanner6h 10m04:49 PMSt. Louis Lambert AirportSt. Louis Lambert Airport10:59 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Skyscanner goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 4/22/2026 4:49:00 PM to San Antonio Airport, San Antonio Airport (USA) arriving at 4/22/2026 10:59:00 PM. 50 Economy ticket for $322 per person are available. Travel duration is 6h 10m
Cheapest Buses Wednesday
Cheapest Flights Wednesday
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Frontier Airlines13h 45m09:55 PMSt. Louis Lambert AirportSt. Louis Lambert Airport11:40 AMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 4/23/2026 9:55:00 PM to San Antonio Airport, San Antonio Airport (USA) arriving at 4/24/2026 11:40:00 AM. 50 Economy ticket for $76 per person are available. Travel duration is 13h 45m
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United Airlines7h 8m06:00 AMSt. Louis Lambert AirportSt. Louis Lambert Airport1:08 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 4/23/2026 6:00:00 AM to San Antonio Airport, San Antonio Airport (USA) arriving at 4/23/2026 1:08:00 PM. 50 Economy ticket for $147 per person are available. Travel duration is 7h 8m
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Allegiant Air26h 34m010:43 AMMidAmerica St. Louis AirportMidAmerica St. Louis Airport1:17 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Allegiant Air goes from MidAmerica St. Louis Airport, MidAmerica St. Louis Airport (USA) at 4/23/2026 10:43:00 AM to San Antonio Airport, San Antonio Airport (USA) arriving at 4/24/2026 1:17:00 PM. 50 Economy ticket for $263 per person are available. Travel duration is 26h 34m
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Alaska Airlines10h 5m07:00 AMSt. Louis Lambert AirportSt. Louis Lambert Airport5:05 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Alaska Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 4/23/2026 7:00:00 AM to San Antonio Airport, San Antonio Airport (USA) arriving at 4/23/2026 5:05:00 PM. 50 Economy ticket for $384 per person are available. Travel duration is 10h 5m
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Skyscanner6h 10m04:49 PMSt. Louis Lambert AirportSt. Louis Lambert Airport10:59 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Skyscanner goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 4/23/2026 4:49:00 PM to San Antonio Airport, San Antonio Airport (USA) arriving at 4/23/2026 10:59:00 PM. 50 Economy ticket for $576 per person are available. Travel duration is 6h 10m
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Greyhound US28h 40m04:30 PMSt. Louis, MOGateway Station9:10 PMSan Antonio, TXPearl District0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 4/23/2026 4:30:00 PM to Pearl District, San Antonio, TX (USA) arriving at 4/24/2026 9:10:00 PM. 50 Economy ticket for $103 per person are available. Travel duration is 28h 40m
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Greyhound US22h 35m01:20 AMSt. Louis, MOGateway Station11:55 PMSan Antonio, TXBus Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 4/23/2026 1:20:00 AM to Bus Station, San Antonio, TX (USA) arriving at 4/23/2026 11:55:00 PM. 50 Economy ticket for $104 per person are available. Travel duration is 22h 35m
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Greyhound US23h 45m01:30 AMSt. Louis, MOGateway Station1:15 AMSan Antonio, TXBus Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 4/23/2026 1:30:00 AM to Bus Station, San Antonio, TX (USA) arriving at 4/24/2026 1:15:00 AM. 50 Economy ticket for $104 per person are available. Travel duration is 23h 45m
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FlixBus20h 55m04:00 PMSt. Louis, MOGateway Station12:55 PMSan Antonio, TXBus Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 4/23/2026 4:00:00 PM to Bus Station, San Antonio, TX (USA) arriving at 4/24/2026 12:55:00 PM. 50 Economy ticket for $105 per person are available. Travel duration is 20h 55m
Cheapest Flights Thursday
Cheapest Buses Thursday
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Greyhound US25h 5m04:30 PMSt. Louis, MOGateway Station5:35 PMSan Antonio, TXBus Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 4/24/2026 4:30:00 PM to Bus Station, San Antonio, TX (USA) arriving at 4/25/2026 5:35:00 PM. 50 Economy ticket for $111 per person are available. Travel duration is 25h 5m
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FlixBus20h 55m04:00 PMSt. Louis, MOGateway Station12:55 PMSan Antonio, TXBus Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 4/24/2026 4:00:00 PM to Bus Station, San Antonio, TX (USA) arriving at 4/25/2026 12:55:00 PM. 50 Economy ticket for $111 per person are available. Travel duration is 20h 55m
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Greyhound US28h 40m04:30 PMSt. Louis, MOGateway Station9:10 PMSan Antonio, TXPearl District0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 4/24/2026 4:30:00 PM to Pearl District, San Antonio, TX (USA) arriving at 4/25/2026 9:10:00 PM. 50 Economy ticket for $112 per person are available. Travel duration is 28h 40m
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FlixBus29h 15m011:45 PMSt. Louis, MOGateway Station5:00 AMSan Antonio, TXBus Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 4/24/2026 11:45:00 PM to Bus Station, San Antonio, TX (USA) arriving at 4/26/2026 5:00:00 AM. 50 Economy ticket for $112 per person are available. Travel duration is 29h 15m
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Frontier Airlines19h 3m08:06 PMSt. Louis Lambert AirportSt. Louis Lambert Airport3:09 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 4/24/2026 8:06:00 PM to San Antonio Airport, San Antonio Airport (USA) arriving at 4/25/2026 3:09:00 PM. 50 Economy ticket for $125 per person are available. Travel duration is 19h 3m
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United Airlines4h 50m06:00 AMSt. Louis Lambert AirportSt. Louis Lambert Airport10:50 AMSan Antonio AirportSan Antonio Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 4/24/2026 6:00:00 AM to San Antonio Airport, San Antonio Airport (USA) arriving at 4/24/2026 10:50:00 AM. 50 Economy ticket for $179 per person are available. Travel duration is 4h 50m
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United Airlines7h 8m06:00 AMSt. Louis Lambert AirportSt. Louis Lambert Airport1:08 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 4/24/2026 6:00:00 AM to San Antonio Airport, San Antonio Airport (USA) arriving at 4/24/2026 1:08:00 PM. 50 Economy ticket for $183 per person are available. Travel duration is 7h 8m
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Frontier Airlines20h 18m04:59 PMSt. Louis Lambert AirportSt. Louis Lambert Airport1:17 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 4/24/2026 4:59:00 PM to San Antonio Airport, San Antonio Airport (USA) arriving at 4/25/2026 1:17:00 PM. 50 Economy ticket for $188 per person are available. Travel duration is 20h 18m
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Alaska Airlines24h 19m04:46 PMSt. Louis Lambert AirportSt. Louis Lambert Airport5:05 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Alaska Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 4/24/2026 4:46:00 PM to San Antonio Airport, San Antonio Airport (USA) arriving at 4/25/2026 5:05:00 PM. 50 Economy ticket for $409 per person are available. Travel duration is 24h 19m
Cheapest Buses Friday
Cheapest Flights Friday
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Greyhound US22h 35m01:20 AMSt. Louis, MOGateway Station11:55 PMSan Antonio, TXBus Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 4/25/2026 1:20:00 AM to Bus Station, San Antonio, TX (USA) arriving at 4/25/2026 11:55:00 PM. 50 Economy ticket for $114 per person are available. Travel duration is 22h 35m
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Greyhound US23h 45m01:30 AMSt. Louis, MOGateway Station1:15 AMSan Antonio, TXBus Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 4/25/2026 1:30:00 AM to Bus Station, San Antonio, TX (USA) arriving at 4/26/2026 1:15:00 AM. 50 Economy ticket for $114 per person are available. Travel duration is 23h 45m
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Greyhound US25h 5m04:30 PMSt. Louis, MOGateway Station5:35 PMSan Antonio, TXBus Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 4/25/2026 4:30:00 PM to Bus Station, San Antonio, TX (USA) arriving at 4/26/2026 5:35:00 PM. 50 Economy ticket for $114 per person are available. Travel duration is 25h 5m
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FlixBus20h 55m04:00 PMSt. Louis, MOGateway Station12:55 PMSan Antonio, TXBus Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 4/25/2026 4:00:00 PM to Bus Station, San Antonio, TX (USA) arriving at 4/26/2026 12:55:00 PM. 50 Economy ticket for $114 per person are available. Travel duration is 20h 55m
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Frontier Airlines17h 56m08:17 PMSt. Louis Lambert AirportSt. Louis Lambert Airport2:13 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 4/25/2026 8:17:00 PM to San Antonio Airport, San Antonio Airport (USA) arriving at 4/26/2026 2:13:00 PM. 50 Economy ticket for $139 per person are available. Travel duration is 17h 56m
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United Airlines4h 50m06:00 AMSt. Louis Lambert AirportSt. Louis Lambert Airport10:50 AMSan Antonio AirportSan Antonio Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 4/25/2026 6:00:00 AM to San Antonio Airport, San Antonio Airport (USA) arriving at 4/25/2026 10:50:00 AM. 50 Economy ticket for $148 per person are available. Travel duration is 4h 50m
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United Airlines7h 8m06:00 AMSt. Louis Lambert AirportSt. Louis Lambert Airport1:08 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 4/25/2026 6:00:00 AM to San Antonio Airport, San Antonio Airport (USA) arriving at 4/25/2026 1:08:00 PM. 50 Economy ticket for $153 per person are available. Travel duration is 7h 8m
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Frontier Airlines20h 18m04:59 PMSt. Louis Lambert AirportSt. Louis Lambert Airport1:17 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 4/25/2026 4:59:00 PM to San Antonio Airport, San Antonio Airport (USA) arriving at 4/26/2026 1:17:00 PM. 50 Economy ticket for $221 per person are available. Travel duration is 20h 18m
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Alaska Airlines24h 19m04:46 PMSt. Louis Lambert AirportSt. Louis Lambert Airport5:05 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Alaska Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 4/25/2026 4:46:00 PM to San Antonio Airport, San Antonio Airport (USA) arriving at 4/26/2026 5:05:00 PM. 50 Economy ticket for $653 per person are available. Travel duration is 24h 19m
Cheapest Buses Saturday
Cheapest Flights Saturday
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Greyhound US22h 35m01:20 AMSt. Louis, MOGateway Station11:55 PMSan Antonio, TXBus Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 4/26/2026 1:20:00 AM to Bus Station, San Antonio, TX (USA) arriving at 4/26/2026 11:55:00 PM. 50 Economy ticket for $111 per person are available. Travel duration is 22h 35m
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Greyhound US25h 5m04:30 PMSt. Louis, MOGateway Station5:35 PMSan Antonio, TXBus Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 4/26/2026 4:30:00 PM to Bus Station, San Antonio, TX (USA) arriving at 4/27/2026 5:35:00 PM. 50 Economy ticket for $111 per person are available. Travel duration is 25h 5m
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FlixBus20h 55m04:00 PMSt. Louis, MOGateway Station12:55 PMSan Antonio, TXBus Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 4/26/2026 4:00:00 PM to Bus Station, San Antonio, TX (USA) arriving at 4/27/2026 12:55:00 PM. 50 Economy ticket for $111 per person are available. Travel duration is 20h 55m
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Greyhound US23h 45m01:30 AMSt. Louis, MOGateway Station1:15 AMSan Antonio, TXBus Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 4/26/2026 1:30:00 AM to Bus Station, San Antonio, TX (USA) arriving at 4/27/2026 1:15:00 AM. 50 Economy ticket for $112 per person are available. Travel duration is 23h 45m
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Frontier Airlines18h 9m08:06 PMSt. Louis Lambert AirportSt. Louis Lambert Airport2:15 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 4/26/2026 8:06:00 PM to San Antonio Airport, San Antonio Airport (USA) arriving at 4/27/2026 2:15:00 PM. 50 Economy ticket for $193 per person are available. Travel duration is 18h 9m
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United Airlines4h 50m06:00 AMSt. Louis Lambert AirportSt. Louis Lambert Airport10:50 AMSan Antonio AirportSan Antonio Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 4/26/2026 6:00:00 AM to San Antonio Airport, San Antonio Airport (USA) arriving at 4/26/2026 10:50:00 AM. 50 Economy ticket for $215 per person are available. Travel duration is 4h 50m
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United Airlines7h 8m06:00 AMSt. Louis Lambert AirportSt. Louis Lambert Airport1:08 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 4/26/2026 6:00:00 AM to San Antonio Airport, San Antonio Airport (USA) arriving at 4/26/2026 1:08:00 PM. 50 Economy ticket for $255 per person are available. Travel duration is 7h 8m
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Frontier Airlines20h 18m04:59 PMSt. Louis Lambert AirportSt. Louis Lambert Airport1:17 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 4/26/2026 4:59:00 PM to San Antonio Airport, San Antonio Airport (USA) arriving at 4/27/2026 1:17:00 PM. 50 Economy ticket for $300 per person are available. Travel duration is 20h 18m
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Alaska Airlines10h 5m07:00 AMSt. Louis Lambert AirportSt. Louis Lambert Airport5:05 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Alaska Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 4/26/2026 7:00:00 AM to San Antonio Airport, San Antonio Airport (USA) arriving at 4/26/2026 5:05:00 PM. 50 Economy ticket for $445 per person are available. Travel duration is 10h 5m
Cheapest Buses Sunday
Cheapest Flights Sunday
What are the fastest trips from St. Louis, MO to San Antonio, TX?
You can get to San Antonio, TX from St. Louis, MO in just 4h 50m with a Flight from United Airlines. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.
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United Airlines6h 2m02:40 PMSt. Louis Lambert AirportSt. Louis Lambert Airport8:42 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 4/20/2026 2:40:00 PM to San Antonio Airport, San Antonio Airport (USA) arriving at 4/20/2026 8:42:00 PM. 50 Economy ticket for $196 per person are available. Travel duration is 6h 2m
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United Airlines7h 8m06:00 AMSt. Louis Lambert AirportSt. Louis Lambert Airport1:08 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 4/20/2026 6:00:00 AM to San Antonio Airport, San Antonio Airport (USA) arriving at 4/20/2026 1:08:00 PM. 50 Economy ticket for $194 per person are available. Travel duration is 7h 8m
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Alaska Airlines9h 54m07:00 AMSt. Louis Lambert AirportSt. Louis Lambert Airport4:54 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Alaska Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 4/20/2026 7:00:00 AM to San Antonio Airport, San Antonio Airport (USA) arriving at 4/20/2026 4:54:00 PM. 50 Economy ticket for $424 per person are available. Travel duration is 9h 54m
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Frontier Airlines18h 52m08:17 PMSt. Louis Lambert AirportSt. Louis Lambert Airport3:09 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 4/20/2026 8:17:00 PM to San Antonio Airport, San Antonio Airport (USA) arriving at 4/21/2026 3:09:00 PM. 50 Economy ticket for $115 per person are available. Travel duration is 18h 52m
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FlixBus20h 55m04:00 PMSt. Louis, MOGateway Station12:55 PMSan Antonio, TXBus Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 4/20/2026 4:00:00 PM to Bus Station, San Antonio, TX (USA) arriving at 4/21/2026 12:55:00 PM. 50 Economy ticket for $107 per person are available. Travel duration is 20h 55m
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Greyhound US22h 35m01:20 AMSt. Louis, MOGateway Station11:55 PMSan Antonio, TXBus Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 4/20/2026 1:20:00 AM to Bus Station, San Antonio, TX (USA) arriving at 4/20/2026 11:55:00 PM. 50 Economy ticket for $108 per person are available. Travel duration is 22h 35m
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Greyhound US25h 5m04:30 PMSt. Louis, MOGateway Station5:35 PMSan Antonio, TXBus Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 4/20/2026 4:30:00 PM to Bus Station, San Antonio, TX (USA) arriving at 4/21/2026 5:35:00 PM. 50 Economy ticket for $105 per person are available. Travel duration is 25h 5m
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Greyhound US30h 55m04:30 PMSt. Louis, MOGateway Station11:25 PMSan Antonio, TXPearl District0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 4/20/2026 4:30:00 PM to Pearl District, San Antonio, TX (USA) arriving at 4/21/2026 11:25:00 PM. 50 Economy ticket for $106 per person are available. Travel duration is 30h 55m
Fastest Flights Monday
Fastest Buses Monday
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United Airlines4h 50m06:00 AMSt. Louis Lambert AirportSt. Louis Lambert Airport10:50 AMSan Antonio AirportSan Antonio Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 4/21/2026 6:00:00 AM to San Antonio Airport, San Antonio Airport (USA) arriving at 4/21/2026 10:50:00 AM. 50 Economy ticket for $143 per person are available. Travel duration is 4h 50m
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United Airlines8h 2m08:54 AMSt. Louis Lambert AirportSt. Louis Lambert Airport4:56 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 4/21/2026 8:54:00 AM to San Antonio Airport, San Antonio Airport (USA) arriving at 4/21/2026 4:56:00 PM. 50 Economy ticket for $168 per person are available. Travel duration is 8h 2m
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Alaska Airlines9h 54m07:00 AMSt. Louis Lambert AirportSt. Louis Lambert Airport4:54 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Alaska Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 4/21/2026 7:00:00 AM to San Antonio Airport, San Antonio Airport (USA) arriving at 4/21/2026 4:54:00 PM. 50 Economy ticket for $420 per person are available. Travel duration is 9h 54m
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Frontier Airlines20h 18m04:59 PMSt. Louis Lambert AirportSt. Louis Lambert Airport1:17 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 4/21/2026 4:59:00 PM to San Antonio Airport, San Antonio Airport (USA) arriving at 4/22/2026 1:17:00 PM. 50 Economy ticket for $226 per person are available. Travel duration is 20h 18m
Fastest Flights Tuesday
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United Airlines4h 50m06:00 AMSt. Louis Lambert AirportSt. Louis Lambert Airport10:50 AMSan Antonio AirportSan Antonio Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 4/22/2026 6:00:00 AM to San Antonio Airport, San Antonio Airport (USA) arriving at 4/22/2026 10:50:00 AM. 50 Economy ticket for $142 per person are available. Travel duration is 4h 50m
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Skyscanner6h 10m04:49 PMSt. Louis Lambert AirportSt. Louis Lambert Airport10:59 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Skyscanner goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 4/22/2026 4:49:00 PM to San Antonio Airport, San Antonio Airport (USA) arriving at 4/22/2026 10:59:00 PM. 50 Economy ticket for $322 per person are available. Travel duration is 6h 10m
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United Airlines8h 2m08:54 AMSt. Louis Lambert AirportSt. Louis Lambert Airport4:56 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 4/22/2026 8:54:00 AM to San Antonio Airport, San Antonio Airport (USA) arriving at 4/22/2026 4:56:00 PM. 50 Economy ticket for $147 per person are available. Travel duration is 8h 2m
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Frontier Airlines20h 18m04:59 PMSt. Louis Lambert AirportSt. Louis Lambert Airport1:17 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 4/22/2026 4:59:00 PM to San Antonio Airport, San Antonio Airport (USA) arriving at 4/23/2026 1:17:00 PM. 50 Economy ticket for $217 per person are available. Travel duration is 20h 18m
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Greyhound US22h 35m01:20 AMSt. Louis, MOGateway Station11:55 PMSan Antonio, TXBus Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 4/22/2026 1:20:00 AM to Bus Station, San Antonio, TX (USA) arriving at 4/22/2026 11:55:00 PM. 50 Economy ticket for $120 per person are available. Travel duration is 22h 35m
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Greyhound US23h 45m01:30 AMSt. Louis, MOGateway Station1:15 AMSan Antonio, TXBus Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 4/22/2026 1:30:00 AM to Bus Station, San Antonio, TX (USA) arriving at 4/23/2026 1:15:00 AM. 50 Economy ticket for $119 per person are available. Travel duration is 23h 45m
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Greyhound US25h 5m04:30 PMSt. Louis, MOGateway Station5:35 PMSan Antonio, TXBus Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 4/22/2026 4:30:00 PM to Bus Station, San Antonio, TX (USA) arriving at 4/23/2026 5:35:00 PM. 50 Economy ticket for $119 per person are available. Travel duration is 25h 5m
Fastest Flights Wednesday
Fastest Buses Wednesday
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Skyscanner6h 10m04:49 PMSt. Louis Lambert AirportSt. Louis Lambert Airport10:59 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Skyscanner goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 4/23/2026 4:49:00 PM to San Antonio Airport, San Antonio Airport (USA) arriving at 4/23/2026 10:59:00 PM. 50 Economy ticket for $576 per person are available. Travel duration is 6h 10m
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United Airlines7h 8m06:00 AMSt. Louis Lambert AirportSt. Louis Lambert Airport1:08 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 4/23/2026 6:00:00 AM to San Antonio Airport, San Antonio Airport (USA) arriving at 4/23/2026 1:08:00 PM. 50 Economy ticket for $147 per person are available. Travel duration is 7h 8m
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Alaska Airlines10h 5m07:00 AMSt. Louis Lambert AirportSt. Louis Lambert Airport5:05 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Alaska Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 4/23/2026 7:00:00 AM to San Antonio Airport, San Antonio Airport (USA) arriving at 4/23/2026 5:05:00 PM. 50 Economy ticket for $384 per person are available. Travel duration is 10h 5m
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Frontier Airlines13h 45m09:55 PMSt. Louis Lambert AirportSt. Louis Lambert Airport11:40 AMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 4/23/2026 9:55:00 PM to San Antonio Airport, San Antonio Airport (USA) arriving at 4/24/2026 11:40:00 AM. 50 Economy ticket for $76 per person are available. Travel duration is 13h 45m
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Allegiant Air26h 34m010:43 AMMidAmerica St. Louis AirportMidAmerica St. Louis Airport1:17 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Allegiant Air goes from MidAmerica St. Louis Airport, MidAmerica St. Louis Airport (USA) at 4/23/2026 10:43:00 AM to San Antonio Airport, San Antonio Airport (USA) arriving at 4/24/2026 1:17:00 PM. 50 Economy ticket for $263 per person are available. Travel duration is 26h 34m
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FlixBus20h 55m04:00 PMSt. Louis, MOGateway Station12:55 PMSan Antonio, TXBus Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 4/23/2026 4:00:00 PM to Bus Station, San Antonio, TX (USA) arriving at 4/24/2026 12:55:00 PM. 50 Economy ticket for $105 per person are available. Travel duration is 20h 55m
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Greyhound US22h 35m01:20 AMSt. Louis, MOGateway Station11:55 PMSan Antonio, TXBus Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 4/23/2026 1:20:00 AM to Bus Station, San Antonio, TX (USA) arriving at 4/23/2026 11:55:00 PM. 50 Economy ticket for $104 per person are available. Travel duration is 22h 35m
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Greyhound US23h 45m01:30 AMSt. Louis, MOGateway Station1:15 AMSan Antonio, TXBus Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 4/23/2026 1:30:00 AM to Bus Station, San Antonio, TX (USA) arriving at 4/24/2026 1:15:00 AM. 50 Economy ticket for $104 per person are available. Travel duration is 23h 45m
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Greyhound US28h 40m04:30 PMSt. Louis, MOGateway Station9:10 PMSan Antonio, TXPearl District0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 4/23/2026 4:30:00 PM to Pearl District, San Antonio, TX (USA) arriving at 4/24/2026 9:10:00 PM. 50 Economy ticket for $103 per person are available. Travel duration is 28h 40m
Fastest Flights Thursday
Fastest Buses Thursday
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United Airlines4h 50m06:00 AMSt. Louis Lambert AirportSt. Louis Lambert Airport10:50 AMSan Antonio AirportSan Antonio Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 4/24/2026 6:00:00 AM to San Antonio Airport, San Antonio Airport (USA) arriving at 4/24/2026 10:50:00 AM. 50 Economy ticket for $179 per person are available. Travel duration is 4h 50m
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United Airlines7h 8m06:00 AMSt. Louis Lambert AirportSt. Louis Lambert Airport1:08 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 4/24/2026 6:00:00 AM to San Antonio Airport, San Antonio Airport (USA) arriving at 4/24/2026 1:08:00 PM. 50 Economy ticket for $183 per person are available. Travel duration is 7h 8m
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Frontier Airlines19h 3m08:06 PMSt. Louis Lambert AirportSt. Louis Lambert Airport3:09 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 4/24/2026 8:06:00 PM to San Antonio Airport, San Antonio Airport (USA) arriving at 4/25/2026 3:09:00 PM. 50 Economy ticket for $125 per person are available. Travel duration is 19h 3m
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Frontier Airlines20h 18m04:59 PMSt. Louis Lambert AirportSt. Louis Lambert Airport1:17 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 4/24/2026 4:59:00 PM to San Antonio Airport, San Antonio Airport (USA) arriving at 4/25/2026 1:17:00 PM. 50 Economy ticket for $188 per person are available. Travel duration is 20h 18m
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Alaska Airlines24h 19m04:46 PMSt. Louis Lambert AirportSt. Louis Lambert Airport5:05 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Alaska Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 4/24/2026 4:46:00 PM to San Antonio Airport, San Antonio Airport (USA) arriving at 4/25/2026 5:05:00 PM. 50 Economy ticket for $409 per person are available. Travel duration is 24h 19m
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FlixBus20h 55m04:00 PMSt. Louis, MOGateway Station12:55 PMSan Antonio, TXBus Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 4/24/2026 4:00:00 PM to Bus Station, San Antonio, TX (USA) arriving at 4/25/2026 12:55:00 PM. 50 Economy ticket for $111 per person are available. Travel duration is 20h 55m
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Greyhound US25h 5m04:30 PMSt. Louis, MOGateway Station5:35 PMSan Antonio, TXBus Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 4/24/2026 4:30:00 PM to Bus Station, San Antonio, TX (USA) arriving at 4/25/2026 5:35:00 PM. 50 Economy ticket for $111 per person are available. Travel duration is 25h 5m
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Greyhound US28h 40m04:30 PMSt. Louis, MOGateway Station9:10 PMSan Antonio, TXPearl District0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 4/24/2026 4:30:00 PM to Pearl District, San Antonio, TX (USA) arriving at 4/25/2026 9:10:00 PM. 50 Economy ticket for $112 per person are available. Travel duration is 28h 40m
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FlixBus29h 15m011:45 PMSt. Louis, MOGateway Station5:00 AMSan Antonio, TXBus Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 4/24/2026 11:45:00 PM to Bus Station, San Antonio, TX (USA) arriving at 4/26/2026 5:00:00 AM. 50 Economy ticket for $112 per person are available. Travel duration is 29h 15m
Fastest Flights Friday
Fastest Buses Friday
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United Airlines4h 50m06:00 AMSt. Louis Lambert AirportSt. Louis Lambert Airport10:50 AMSan Antonio AirportSan Antonio Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 4/25/2026 6:00:00 AM to San Antonio Airport, San Antonio Airport (USA) arriving at 4/25/2026 10:50:00 AM. 50 Economy ticket for $148 per person are available. Travel duration is 4h 50m
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United Airlines7h 8m06:00 AMSt. Louis Lambert AirportSt. Louis Lambert Airport1:08 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 4/25/2026 6:00:00 AM to San Antonio Airport, San Antonio Airport (USA) arriving at 4/25/2026 1:08:00 PM. 50 Economy ticket for $153 per person are available. Travel duration is 7h 8m
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Frontier Airlines17h 56m08:17 PMSt. Louis Lambert AirportSt. Louis Lambert Airport2:13 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 4/25/2026 8:17:00 PM to San Antonio Airport, San Antonio Airport (USA) arriving at 4/26/2026 2:13:00 PM. 50 Economy ticket for $139 per person are available. Travel duration is 17h 56m
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Frontier Airlines20h 18m04:59 PMSt. Louis Lambert AirportSt. Louis Lambert Airport1:17 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 4/25/2026 4:59:00 PM to San Antonio Airport, San Antonio Airport (USA) arriving at 4/26/2026 1:17:00 PM. 50 Economy ticket for $221 per person are available. Travel duration is 20h 18m
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Alaska Airlines24h 19m04:46 PMSt. Louis Lambert AirportSt. Louis Lambert Airport5:05 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Alaska Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 4/25/2026 4:46:00 PM to San Antonio Airport, San Antonio Airport (USA) arriving at 4/26/2026 5:05:00 PM. 50 Economy ticket for $653 per person are available. Travel duration is 24h 19m
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FlixBus20h 55m04:00 PMSt. Louis, MOGateway Station12:55 PMSan Antonio, TXBus Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 4/25/2026 4:00:00 PM to Bus Station, San Antonio, TX (USA) arriving at 4/26/2026 12:55:00 PM. 50 Economy ticket for $114 per person are available. Travel duration is 20h 55m
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Greyhound US22h 35m01:20 AMSt. Louis, MOGateway Station11:55 PMSan Antonio, TXBus Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 4/25/2026 1:20:00 AM to Bus Station, San Antonio, TX (USA) arriving at 4/25/2026 11:55:00 PM. 50 Economy ticket for $114 per person are available. Travel duration is 22h 35m
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Greyhound US23h 45m01:30 AMSt. Louis, MOGateway Station1:15 AMSan Antonio, TXBus Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 4/25/2026 1:30:00 AM to Bus Station, San Antonio, TX (USA) arriving at 4/26/2026 1:15:00 AM. 50 Economy ticket for $114 per person are available. Travel duration is 23h 45m
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Greyhound US25h 5m04:30 PMSt. Louis, MOGateway Station5:35 PMSan Antonio, TXBus Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 4/25/2026 4:30:00 PM to Bus Station, San Antonio, TX (USA) arriving at 4/26/2026 5:35:00 PM. 50 Economy ticket for $114 per person are available. Travel duration is 25h 5m
Fastest Flights Saturday
Fastest Buses Saturday
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United Airlines4h 50m06:00 AMSt. Louis Lambert AirportSt. Louis Lambert Airport10:50 AMSan Antonio AirportSan Antonio Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 4/26/2026 6:00:00 AM to San Antonio Airport, San Antonio Airport (USA) arriving at 4/26/2026 10:50:00 AM. 50 Economy ticket for $215 per person are available. Travel duration is 4h 50m
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United Airlines7h 8m06:00 AMSt. Louis Lambert AirportSt. Louis Lambert Airport1:08 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from United Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 4/26/2026 6:00:00 AM to San Antonio Airport, San Antonio Airport (USA) arriving at 4/26/2026 1:08:00 PM. 50 Economy ticket for $255 per person are available. Travel duration is 7h 8m
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Alaska Airlines10h 5m07:00 AMSt. Louis Lambert AirportSt. Louis Lambert Airport5:05 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Alaska Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 4/26/2026 7:00:00 AM to San Antonio Airport, San Antonio Airport (USA) arriving at 4/26/2026 5:05:00 PM. 50 Economy ticket for $445 per person are available. Travel duration is 10h 5m
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Frontier Airlines18h 9m08:06 PMSt. Louis Lambert AirportSt. Louis Lambert Airport2:15 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 4/26/2026 8:06:00 PM to San Antonio Airport, San Antonio Airport (USA) arriving at 4/27/2026 2:15:00 PM. 50 Economy ticket for $193 per person are available. Travel duration is 18h 9m
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Frontier Airlines20h 18m04:59 PMSt. Louis Lambert AirportSt. Louis Lambert Airport1:17 PMSan Antonio AirportSan Antonio Airport0EconomyA Flight from Frontier Airlines goes from St. Louis Lambert Airport, St. Louis Lambert Airport (USA) at 4/26/2026 4:59:00 PM to San Antonio Airport, San Antonio Airport (USA) arriving at 4/27/2026 1:17:00 PM. 50 Economy ticket for $300 per person are available. Travel duration is 20h 18m
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FlixBus20h 55m04:00 PMSt. Louis, MOGateway Station12:55 PMSan Antonio, TXBus Station0EconomyA Bus from FlixBus goes from Gateway Station, St. Louis, MO (USA) at 4/26/2026 4:00:00 PM to Bus Station, San Antonio, TX (USA) arriving at 4/27/2026 12:55:00 PM. 50 Economy ticket for $111 per person are available. Travel duration is 20h 55m
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Greyhound US22h 35m01:20 AMSt. Louis, MOGateway Station11:55 PMSan Antonio, TXBus Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 4/26/2026 1:20:00 AM to Bus Station, San Antonio, TX (USA) arriving at 4/26/2026 11:55:00 PM. 50 Economy ticket for $111 per person are available. Travel duration is 22h 35m
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Greyhound US23h 45m01:30 AMSt. Louis, MOGateway Station1:15 AMSan Antonio, TXBus Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 4/26/2026 1:30:00 AM to Bus Station, San Antonio, TX (USA) arriving at 4/27/2026 1:15:00 AM. 50 Economy ticket for $112 per person are available. Travel duration is 23h 45m
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Greyhound US25h 5m04:30 PMSt. Louis, MOGateway Station5:35 PMSan Antonio, TXBus Station0EconomyA Bus from Greyhound US goes from Gateway Station, St. Louis, MO (USA) at 4/26/2026 4:30:00 PM to Bus Station, San Antonio, TX (USA) arriving at 4/27/2026 5:35:00 PM. 50 Economy ticket for $111 per person are available. Travel duration is 25h 5m
Fastest Flights Sunday
Fastest Buses Sunday
Here you will find all operators and timetables for a
Bus from St. Louis, MO to San Antonio, TX
What are the most popular stations in St. Louis, MO and San Antonio, TX?
In St. Louis, MO, you will usually depart from Gateway Station, Lindbergh @ Hackberry NB Bus Stop or Skinker Boulevard, while in San Antonio, TX you will be arriving at Tornado Bus Company, Bus Station or W. Southcross & Buffalo Bus Stop, but there are many more stops to explore in both locations.
How do I decide? Some tips and tricks from our experience
Are you having trouble deciding on how to get to San Antonio, TX from St. Louis, MO? With 9 connections between 2 Flight and Bus operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.
Look for the lowest price
Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between St. Louis, MO and San Antonio, TX, you can pay as low as $76 with a Flight from Frontier Airlines.Travel duration
Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from United Airlines: you will get to San Antonio, TX in just 4h 50m.Comfort makes all the difference
You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting St. Louis, MO and San Antonio, TX are Greyhound US, United Airlines and Frontier Airlines, but be sure to check what they have to offer!Save money with deals, and always compare
One last tip? Even if you live in St. Louis, MO and San Antonio, TX is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from Sauget, IL or to Olmos Park, TX, and look at flights from St. Louis Lambert Airport, and landing at San Antonio Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!Which companies offer a trip from St. Louis, MO to San Antonio, TX?
The most popular companies between St. Louis, MO and San Antonio, TX, are Greyhound US, United Airlines and Frontier Airlines. Be sure to check their seat class offers and the amenities that they provide.
Bus companies: Greyhound US and FlixBus
Airlines: United Airlines, Frontier Airlines, Alaska Airlines and 2 more.
All you need to know when you travel from St. Louis, MO to San Antonio, TX
Check all information on comfort and services on all modes of transports from St. Louis, MO to San Antonio, TX. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.
FAQs about the trip from St. Louis, MO to San Antonio, TX
How can I reach San Antonio, TX from St. Louis, MO?
Every day, there are on average 9 connections between Flight and Bus, with which you can get to San Antonio, TX from St. Louis, MO.
How far is San Antonio, TX from St. Louis, MO?
The distance between St. Louis, MO and San Antonio, TX is 792.3 miles.
What is the most ecofriendly mode of transport between St. Louis, MO and San Antonio, TX?
Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance.
On this particular route, a bus will emit, per person, a total of 34 kgs of CO2, a train 45 kgs, a car 217 kgs, and a flight 314 kgs.
What is the cheapest mode of transport from St. Louis, MO to San Antonio, TX?
You can get to San Antonio, TX with just $76 by taking a Flight from Frontier Airlines.
What is the fastest way to get from St. Louis, MO to San Antonio, TX?
While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to San Antonio, TX in just 4h 50m with a Flight from United Airlines.
More routes to St. Louis, MO and to San Antonio, TX
Looking for more options? Here you can see the most popular routes to St. Louis, MO and to San Antonio, TX. Simply click on a connection, and you’ll find all the details about the route!
