How to get from Houston to St. Louis, MO

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What is the best way to travel from Houston to St. Louis, MO?

Looking for a trip? Compare all the available Buses and Flights for the journey to St. Louis, MO from Houston. Check between different modes of transportation, look for the cheapest tickets, fastest rides and most popular stations, and see all 5 available companies to find your perfect trip!
Bus is the cheapest, while Flight is the fastest way on this route
Transport type
Travel time
Cheapest price
Average price
Daily departures
Bus
22h 40m
$150
$168
28
Flight
2h 4m
$207
$335
69

What is the cheapest way to reach St. Louis, MO from Houston?

You can get to St. Louis, MO with just $150 by taking a Bus from Greyhound US, but you can find many more cheap offers: we have selected the best ones for next few days here for you.

Friday
from $174
Saturday
from $150
Sunday
from $172
Monday
from $160
Tuesday
from $171
Wednesday
from $240
Thursday
from $158

    Cheapest Buses Friday

  • FlixBus
    22h 40m
    0
    5:05 PM
    Houston
    Downtown Houston
    3:45 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $174
  • Greyhound US
    25h 0m
    0
    10:00 PM
    Houston
    Harrisburg Blvd Station
    11:00 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $176
  • FlixBus
    25h 55m
    0
    1:50 PM
    Houston
    Uptown/Upper Kirby
    3:45 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $176
  • Valley Transit
    30h 20m
    0
    6:35 AM
    Houston
    SW Agencia Autobuses
    12:55 PM
    St. Louis, MO
    Gateway Station
    0
    Valley Transit
    Economy
    $237
  • Cheapest Flights Friday

  • Frontier Airlines
    12h 7m
    0
    9:55 PM
    George Bush Intercontinental Houston Airport
    George Bush Intercontinental Houston Airport
    10:02 AM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Frontier Airlines
    Economy
    from $237
  • United Airlines
    2h 5m
    0
    7:50 PM
    George Bush Intercontinental Houston Airport
    George Bush Intercontinental Houston Airport
    9:55 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    United Airlines
    Economy
    from $443
  • Skyscanner
    2h 4m
    0
    7:45 AM
    George Bush Intercontinental Houston Airport
    George Bush Intercontinental Houston Airport
    9:49 AM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Skyscanner
    Economy
    from $443
  • Skyscanner
    2h 8m
    0
    2:28 PM
    George Bush Intercontinental Houston Airport
    George Bush Intercontinental Houston Airport
    4:36 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Skyscanner
    Economy
    from $443
  • United Airlines
    5h 57m
    0
    6:30 AM
    George Bush Intercontinental Houston Airport
    George Bush Intercontinental Houston Airport
    12:27 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    United Airlines
    Economy
    from $453

    Cheapest Buses Saturday

  • Greyhound US
    23h 10m
    0
    1:45 PM
    Houston
    Harrisburg Blvd Station
    12:55 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $150
  • FlixBus
    28h 50m
    0
    6:00 PM
    Houston
    Downtown Houston
    10:50 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $150
  • Greyhound Lines Mexico
    37h 20m
    0
    9:30 AM
    Houston
    SW Agencia Autobuses
    10:50 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound Lines Mexico
    Economy
    $151
  • FlixBus
    25h 30m
    0
    11:25 AM
    Houston
    Uptown/Upper Kirby
    12:55 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $151
  • Greyhound US
    27h 50m
    0
    7:00 PM
    Houston
    Harrisburg Blvd Station
    10:50 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $152

    Cheapest Buses Sunday

  • FlixBus
    22h 40m
    0
    5:05 PM
    Houston
    Downtown Houston
    3:45 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $172
  • Greyhound US
    27h 55m
    0
    6:55 PM
    Houston
    Harrisburg Blvd Station
    10:50 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $177
  • FlixBus
    30h 20m
    0
    6:35 AM
    Houston
    SW Agencia Autobuses
    12:55 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $177
  • Greyhound US
    23h 10m
    0
    1:45 PM
    Houston
    Harrisburg Blvd Station
    12:55 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $181
  • Valley Transit
    30h 20m
    0
    6:35 AM
    Houston
    SW Agencia Autobuses
    12:55 PM
    St. Louis, MO
    Gateway Station
    0
    Valley Transit
    Economy
    $182
  • Cheapest Flights Sunday

  • Frontier Airlines
    12h 11m
    0
    9:34 PM
    George Bush Intercontinental Houston Airport
    George Bush Intercontinental Houston Airport
    9:45 AM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Frontier Airlines
    Economy
    from $207
  • Frontier Airlines
    30h 53m
    0
    2:32 PM
    George Bush Intercontinental Houston Airport
    George Bush Intercontinental Houston Airport
    9:25 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Frontier Airlines
    Economy
    from $325
  • United Airlines
    2h 5m
    0
    7:50 PM
    George Bush Intercontinental Houston Airport
    George Bush Intercontinental Houston Airport
    9:55 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    United Airlines
    Economy
    from $343
  • Skyscanner
    2h 4m
    0
    7:45 AM
    George Bush Intercontinental Houston Airport
    George Bush Intercontinental Houston Airport
    9:49 AM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Skyscanner
    Economy
    from $344

    Cheapest Buses Monday

  • Greyhound US
    23h 10m
    0
    1:45 PM
    Houston
    Harrisburg Blvd Station
    12:55 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $160
  • FlixBus
    22h 40m
    0
    5:05 PM
    Houston
    Downtown Houston
    3:45 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $160
  • Greyhound US
    22h 55m
    0
    8:15 AM
    Houston
    Harrisburg Blvd Station
    7:10 AM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $161
  • FlixBus
    25h 30m
    0
    11:25 AM
    Houston
    Uptown/Upper Kirby
    12:55 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $161
  • Valley Transit
    30h 20m
    0
    6:35 AM
    Houston
    SW Agencia Autobuses
    12:55 PM
    St. Louis, MO
    Gateway Station
    0
    Valley Transit
    Economy
    $162
  • Cheapest Flights Monday

  • Frontier Airlines
    15h 35m
    0
    6:05 PM
    George Bush Intercontinental Houston Airport
    George Bush Intercontinental Houston Airport
    9:40 AM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Frontier Airlines
    Economy
    from $296
  • Frontier Airlines
    27h 40m
    0
    6:00 AM
    George Bush Intercontinental Houston Airport
    George Bush Intercontinental Houston Airport
    9:40 AM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Frontier Airlines
    Economy
    from $301
  • Spirit Airlines
    18h 31m
    0
    3:09 PM
    George Bush Intercontinental Houston Airport
    George Bush Intercontinental Houston Airport
    9:40 AM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Spirit Airlines
    Economy
    from $321
  • Spirit Airlines
    16h 47m
    0
    5:46 AM
    George Bush Intercontinental Houston Airport
    George Bush Intercontinental Houston Airport
    10:33 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Spirit Airlines
    Economy
    from $333
  • United Airlines
    7h 27m
    0
    5:00 AM
    George Bush Intercontinental Houston Airport
    George Bush Intercontinental Houston Airport
    12:27 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    United Airlines
    Economy
    from $352

    Cheapest Buses Tuesday

  • Greyhound US
    23h 10m
    0
    1:45 PM
    Houston
    Harrisburg Blvd Station
    12:55 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $171
  • FlixBus
    27h 0m
    0
    7:50 PM
    Houston
    Uptown/Upper Kirby
    10:50 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $171
  • Greyhound US
    27h 55m
    0
    6:55 PM
    Houston
    Harrisburg Blvd Station
    10:50 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $172
  • FlixBus
    27h 15m
    0
    7:35 PM
    Houston
    Downtown Houston
    10:50 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $172
  • Valley Transit
    30h 20m
    0
    6:35 AM
    Houston
    SW Agencia Autobuses
    12:55 PM
    St. Louis, MO
    Gateway Station
    0
    Valley Transit
    Economy
    $173
  • Cheapest Flights Tuesday

  • United Airlines
    2h 5m
    0
    7:50 PM
    George Bush Intercontinental Houston Airport
    George Bush Intercontinental Houston Airport
    9:55 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    United Airlines
    Economy
    from $344
  • Skyscanner
    2h 4m
    0
    7:45 AM
    George Bush Intercontinental Houston Airport
    George Bush Intercontinental Houston Airport
    9:49 AM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Skyscanner
    Economy
    from $344
  • Skyscanner
    2h 8m
    0
    2:28 PM
    George Bush Intercontinental Houston Airport
    George Bush Intercontinental Houston Airport
    4:36 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Skyscanner
    Economy
    from $344
  • United Airlines
    5h 57m
    0
    6:30 AM
    George Bush Intercontinental Houston Airport
    George Bush Intercontinental Houston Airport
    12:27 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    United Airlines
    Economy
    from $354
  • Frontier Airlines
    27h 17m
    0
    6:45 AM
    George Bush Intercontinental Houston Airport
    George Bush Intercontinental Houston Airport
    10:02 AM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Frontier Airlines
    Economy
    from $360

    Cheapest Flights Wednesday

  • Spirit Airlines
    24h 48m
    0
    10:08 AM
    George Bush Intercontinental Houston Airport
    George Bush Intercontinental Houston Airport
    10:56 AM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Spirit Airlines
    Economy
    from $240
  • Spirit Airlines
    16h 1m
    0
    6:55 PM
    George Bush Intercontinental Houston Airport
    George Bush Intercontinental Houston Airport
    10:56 AM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Spirit Airlines
    Economy
    from $240
  • United Airlines
    19h 46m
    0
    6:40 PM
    George Bush Intercontinental Houston Airport
    George Bush Intercontinental Houston Airport
    2:26 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    United Airlines
    Economy
    from $252
  • United Airlines
    18h 31m
    0
    7:55 PM
    George Bush Intercontinental Houston Airport
    George Bush Intercontinental Houston Airport
    2:26 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    United Airlines
    Economy
    from $252
  • Frontier Airlines
    15h 35m
    0
    6:05 PM
    George Bush Intercontinental Houston Airport
    George Bush Intercontinental Houston Airport
    9:40 AM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Frontier Airlines
    Economy
    from $304

    Cheapest Buses Thursday

  • Greyhound Lines Mexico
    37h 20m
    0
    9:30 AM
    Houston
    SW Agencia Autobuses
    10:50 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound Lines Mexico
    Economy
    $158
  • Greyhound US
    23h 10m
    0
    1:45 PM
    Houston
    Harrisburg Blvd Station
    12:55 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $159
  • Greyhound US
    27h 55m
    0
    6:55 PM
    Houston
    Harrisburg Blvd Station
    10:50 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $159
  • FlixBus
    22h 40m
    0
    5:05 PM
    Houston
    Downtown Houston
    3:45 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $159
  • Valley Transit
    30h 20m
    0
    6:35 AM
    Houston
    SW Agencia Autobuses
    12:55 PM
    St. Louis, MO
    Gateway Station
    0
    Valley Transit
    Economy
    $160
  • Cheapest Flights Thursday

  • Frontier Airlines
    12h 11m
    0
    9:34 PM
    George Bush Intercontinental Houston Airport
    George Bush Intercontinental Houston Airport
    9:45 AM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Frontier Airlines
    Economy
    from $310
  • Frontier Airlines
    27h 17m
    0
    6:45 AM
    George Bush Intercontinental Houston Airport
    George Bush Intercontinental Houston Airport
    10:02 AM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Frontier Airlines
    Economy
    from $316
  • Spirit Airlines
    14h 0m
    0
    7:45 PM
    George Bush Intercontinental Houston Airport
    George Bush Intercontinental Houston Airport
    9:45 AM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Spirit Airlines
    Economy
    from $326
  • United Airlines
    6h 11m
    0
    8:15 AM
    George Bush Intercontinental Houston Airport
    George Bush Intercontinental Houston Airport
    2:26 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    United Airlines
    Economy
    from $439
  • United Airlines
    4h 56m
    0
    9:30 AM
    George Bush Intercontinental Houston Airport
    George Bush Intercontinental Houston Airport
    2:26 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    United Airlines
    Economy
    from $439

What are the fastest trips from Houston to St. Louis, MO?

You can get to St. Louis, MO from Houston in just 2h 4m with a Flight from Skyscanner. This is not the only option, and you can click on any of the offers below to compare it with the other modes of transportations.

Friday
from 2h 4m
Saturday
from 23h 10m
Sunday
from 2h 4m
Monday
from 7h 27m
Tuesday
from 2h 4m
Wednesday
from 15h 35m
Thursday
from 4h 56m

    Fastest Flights Friday

  • Skyscanner
    2h 4m
    0
    7:45 AM
    George Bush Intercontinental Houston Airport
    George Bush Intercontinental Houston Airport
    9:49 AM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Skyscanner
    Economy
    from $443
  • United Airlines
    2h 5m
    0
    7:50 PM
    George Bush Intercontinental Houston Airport
    George Bush Intercontinental Houston Airport
    9:55 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    United Airlines
    Economy
    from $443
  • Skyscanner
    2h 8m
    0
    2:28 PM
    George Bush Intercontinental Houston Airport
    George Bush Intercontinental Houston Airport
    4:36 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Skyscanner
    Economy
    from $443
  • United Airlines
    5h 57m
    0
    6:30 AM
    George Bush Intercontinental Houston Airport
    George Bush Intercontinental Houston Airport
    12:27 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    United Airlines
    Economy
    from $453
  • Frontier Airlines
    12h 7m
    0
    9:55 PM
    George Bush Intercontinental Houston Airport
    George Bush Intercontinental Houston Airport
    10:02 AM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Frontier Airlines
    Economy
    from $237
  • Fastest Buses Friday

  • FlixBus
    22h 40m
    0
    5:05 PM
    Houston
    Downtown Houston
    3:45 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $174
  • Greyhound US
    25h 0m
    0
    10:00 PM
    Houston
    Harrisburg Blvd Station
    11:00 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $176
  • FlixBus
    25h 55m
    0
    1:50 PM
    Houston
    Uptown/Upper Kirby
    3:45 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $176
  • Valley Transit
    30h 20m
    0
    6:35 AM
    Houston
    SW Agencia Autobuses
    12:55 PM
    St. Louis, MO
    Gateway Station
    0
    Valley Transit
    Economy
    $237

    Fastest Buses Saturday

  • Greyhound US
    23h 10m
    0
    1:45 PM
    Houston
    Harrisburg Blvd Station
    12:55 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $150
  • FlixBus
    25h 30m
    0
    11:25 AM
    Houston
    Uptown/Upper Kirby
    12:55 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $151
  • Greyhound US
    27h 50m
    0
    7:00 PM
    Houston
    Harrisburg Blvd Station
    10:50 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $152
  • FlixBus
    28h 50m
    0
    6:00 PM
    Houston
    Downtown Houston
    10:50 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $150
  • Greyhound Lines Mexico
    37h 20m
    0
    9:30 AM
    Houston
    SW Agencia Autobuses
    10:50 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound Lines Mexico
    Economy
    $151

    Fastest Flights Sunday

  • Skyscanner
    2h 4m
    0
    7:45 AM
    George Bush Intercontinental Houston Airport
    George Bush Intercontinental Houston Airport
    9:49 AM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Skyscanner
    Economy
    from $344
  • United Airlines
    2h 5m
    0
    7:50 PM
    George Bush Intercontinental Houston Airport
    George Bush Intercontinental Houston Airport
    9:55 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    United Airlines
    Economy
    from $343
  • Frontier Airlines
    12h 11m
    0
    9:34 PM
    George Bush Intercontinental Houston Airport
    George Bush Intercontinental Houston Airport
    9:45 AM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Frontier Airlines
    Economy
    from $207
  • Frontier Airlines
    30h 53m
    0
    2:32 PM
    George Bush Intercontinental Houston Airport
    George Bush Intercontinental Houston Airport
    9:25 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Frontier Airlines
    Economy
    from $325
  • Fastest Buses Sunday

  • FlixBus
    22h 40m
    0
    5:05 PM
    Houston
    Downtown Houston
    3:45 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $172
  • Greyhound US
    23h 10m
    0
    1:45 PM
    Houston
    Harrisburg Blvd Station
    12:55 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $181
  • Greyhound US
    27h 55m
    0
    6:55 PM
    Houston
    Harrisburg Blvd Station
    10:50 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $177
  • FlixBus
    30h 20m
    0
    6:35 AM
    Houston
    SW Agencia Autobuses
    12:55 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $177
  • Valley Transit
    30h 20m
    0
    6:35 AM
    Houston
    SW Agencia Autobuses
    12:55 PM
    St. Louis, MO
    Gateway Station
    0
    Valley Transit
    Economy
    $182

    Fastest Flights Monday

  • United Airlines
    7h 27m
    0
    5:00 AM
    George Bush Intercontinental Houston Airport
    George Bush Intercontinental Houston Airport
    12:27 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    United Airlines
    Economy
    from $352
  • Frontier Airlines
    15h 35m
    0
    6:05 PM
    George Bush Intercontinental Houston Airport
    George Bush Intercontinental Houston Airport
    9:40 AM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Frontier Airlines
    Economy
    from $296
  • Spirit Airlines
    16h 47m
    0
    5:46 AM
    George Bush Intercontinental Houston Airport
    George Bush Intercontinental Houston Airport
    10:33 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Spirit Airlines
    Economy
    from $333
  • Spirit Airlines
    18h 31m
    0
    3:09 PM
    George Bush Intercontinental Houston Airport
    George Bush Intercontinental Houston Airport
    9:40 AM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Spirit Airlines
    Economy
    from $321
  • Frontier Airlines
    27h 40m
    0
    6:00 AM
    George Bush Intercontinental Houston Airport
    George Bush Intercontinental Houston Airport
    9:40 AM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Frontier Airlines
    Economy
    from $301
  • Fastest Buses Monday

  • FlixBus
    22h 40m
    0
    5:05 PM
    Houston
    Downtown Houston
    3:45 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $160
  • Greyhound US
    22h 55m
    0
    8:15 AM
    Houston
    Harrisburg Blvd Station
    7:10 AM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $161
  • Greyhound US
    23h 10m
    0
    1:45 PM
    Houston
    Harrisburg Blvd Station
    12:55 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $160
  • FlixBus
    25h 30m
    0
    11:25 AM
    Houston
    Uptown/Upper Kirby
    12:55 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $161
  • Valley Transit
    30h 20m
    0
    6:35 AM
    Houston
    SW Agencia Autobuses
    12:55 PM
    St. Louis, MO
    Gateway Station
    0
    Valley Transit
    Economy
    $162

    Fastest Flights Tuesday

  • Skyscanner
    2h 4m
    0
    7:45 AM
    George Bush Intercontinental Houston Airport
    George Bush Intercontinental Houston Airport
    9:49 AM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Skyscanner
    Economy
    from $344
  • United Airlines
    2h 5m
    0
    7:50 PM
    George Bush Intercontinental Houston Airport
    George Bush Intercontinental Houston Airport
    9:55 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    United Airlines
    Economy
    from $344
  • Skyscanner
    2h 8m
    0
    2:28 PM
    George Bush Intercontinental Houston Airport
    George Bush Intercontinental Houston Airport
    4:36 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Skyscanner
    Economy
    from $344
  • United Airlines
    5h 57m
    0
    6:30 AM
    George Bush Intercontinental Houston Airport
    George Bush Intercontinental Houston Airport
    12:27 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    United Airlines
    Economy
    from $354
  • Frontier Airlines
    27h 17m
    0
    6:45 AM
    George Bush Intercontinental Houston Airport
    George Bush Intercontinental Houston Airport
    10:02 AM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Frontier Airlines
    Economy
    from $360
  • Fastest Buses Tuesday

  • Greyhound US
    23h 10m
    0
    1:45 PM
    Houston
    Harrisburg Blvd Station
    12:55 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $171
  • FlixBus
    27h 0m
    0
    7:50 PM
    Houston
    Uptown/Upper Kirby
    10:50 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $171
  • FlixBus
    27h 15m
    0
    7:35 PM
    Houston
    Downtown Houston
    10:50 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $172
  • Greyhound US
    27h 55m
    0
    6:55 PM
    Houston
    Harrisburg Blvd Station
    10:50 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $172
  • Valley Transit
    30h 20m
    0
    6:35 AM
    Houston
    SW Agencia Autobuses
    12:55 PM
    St. Louis, MO
    Gateway Station
    0
    Valley Transit
    Economy
    $173

    Fastest Flights Wednesday

  • Frontier Airlines
    15h 35m
    0
    6:05 PM
    George Bush Intercontinental Houston Airport
    George Bush Intercontinental Houston Airport
    9:40 AM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Frontier Airlines
    Economy
    from $304
  • Spirit Airlines
    16h 1m
    0
    6:55 PM
    George Bush Intercontinental Houston Airport
    George Bush Intercontinental Houston Airport
    10:56 AM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Spirit Airlines
    Economy
    from $240
  • United Airlines
    18h 31m
    0
    7:55 PM
    George Bush Intercontinental Houston Airport
    George Bush Intercontinental Houston Airport
    2:26 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    United Airlines
    Economy
    from $252
  • United Airlines
    19h 46m
    0
    6:40 PM
    George Bush Intercontinental Houston Airport
    George Bush Intercontinental Houston Airport
    2:26 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    United Airlines
    Economy
    from $252
  • Spirit Airlines
    24h 48m
    0
    10:08 AM
    George Bush Intercontinental Houston Airport
    George Bush Intercontinental Houston Airport
    10:56 AM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Spirit Airlines
    Economy
    from $240

    Fastest Flights Thursday

  • United Airlines
    4h 56m
    0
    9:30 AM
    George Bush Intercontinental Houston Airport
    George Bush Intercontinental Houston Airport
    2:26 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    United Airlines
    Economy
    from $439
  • United Airlines
    6h 11m
    0
    8:15 AM
    George Bush Intercontinental Houston Airport
    George Bush Intercontinental Houston Airport
    2:26 PM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    United Airlines
    Economy
    from $439
  • Frontier Airlines
    12h 11m
    0
    9:34 PM
    George Bush Intercontinental Houston Airport
    George Bush Intercontinental Houston Airport
    9:45 AM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Frontier Airlines
    Economy
    from $310
  • Spirit Airlines
    14h 0m
    0
    7:45 PM
    George Bush Intercontinental Houston Airport
    George Bush Intercontinental Houston Airport
    9:45 AM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Spirit Airlines
    Economy
    from $326
  • Frontier Airlines
    27h 17m
    0
    6:45 AM
    George Bush Intercontinental Houston Airport
    George Bush Intercontinental Houston Airport
    10:02 AM
    St. Louis Lambert Airport
    St. Louis Lambert Airport
    0
    Frontier Airlines
    Economy
    from $316
  • Fastest Buses Thursday

  • FlixBus
    22h 40m
    0
    5:05 PM
    Houston
    Downtown Houston
    3:45 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $159
  • Greyhound US
    23h 10m
    0
    1:45 PM
    Houston
    Harrisburg Blvd Station
    12:55 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $159
  • Greyhound US
    27h 55m
    0
    6:55 PM
    Houston
    Harrisburg Blvd Station
    10:50 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $159
  • Valley Transit
    30h 20m
    0
    6:35 AM
    Houston
    SW Agencia Autobuses
    12:55 PM
    St. Louis, MO
    Gateway Station
    0
    Valley Transit
    Economy
    $160
  • Greyhound Lines Mexico
    37h 20m
    0
    9:30 AM
    Houston
    SW Agencia Autobuses
    10:50 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound Lines Mexico
    Economy
    $158
Here you will find all operators and timetables for a Bus from Houston to St. Louis, MO

What are the most popular stations in Houston and St. Louis, MO?

In Houston, you will usually depart from Hillcroft METRO Park and Ride Bus Station, Lockwood or Main St & Airline Dr, while in St. Louis, MO you will be arriving at Gateway Station, Lindbergh @ Hackberry NB Bus Stop or Skinker Boulevard, but there are many more stops to explore in both locations.

How do I decide? Some tips and tricks from our experience

Are you having trouble deciding on how to get to St. Louis, MO from Houston? With 8 connections between 5 Bus and Flight operators, it can be difficult to find the one ride that will make you happy. But we have some tips that can help you make the best informed decision. First of all, the best trip is always the one that meets all your needs, so make a list of all the things that you want from this journey and look for something that will satisfy all of them. Here we will go through some of the factors mostly commonly taken into consideration.

Look for the lowest price

Ticket price is usually the main concern: even if you can afford to pay more, why do it if there are cheaper options? Saving on the trip means that you can spend more on the vacation itself! Between Houston and St. Louis, MO, you can pay as low as $150 with a Bus from Greyhound US.

Travel duration

Time is also an important factor. An earlier departure may allow you to see a beautiful sunset or relax before an important event. And remember, time is money, so paying more for a shorter trip may be well worth it. For longer distances, flights are without doubt the best options, but be mindful of airport times and possible delays: a high-speed train may end up cheaper and faster! Here the quicker option is definitely the Flight from Skyscanner: you will get to St. Louis, MO in just 2h 4m.

Comfort makes all the difference

You should always take into account what your personal travelling preferences are. Is one hand luggage enough, or are you trasporting more? Would you like to have a snack during the journey? Can you relax in a busy compartment, or do you need space for yourself? Even among the same mode of transportation, different companies will offer you varying levels of comfort and amenities. The main operators connecting Houston and St. Louis, MO are Greyhound US, FlixBus and United Airlines, but be sure to check what they have to offer!

Save money with deals, and always compare

One last tip? Even if you live in Houston and St. Louis, MO is your only destination, it may be wise to check the offers from and to nearby cities or, if you are flyng, nearby airports. Check the trips from West University Place, TX or to Sauget, IL, and look at flights from William P. Hobby Airport, and landing at St. Louis Lambert Airport. Comparing different routes may allow you to find deals or promotions you were not aware of. Consider also signing up to CheckMyBus to see even more exclusive promotions!

Which companies offer a trip from Houston to St. Louis, MO?

The most popular companies between Houston and St. Louis, MO, are Greyhound US, FlixBus and United Airlines. Be sure to check their seat class offers and the amenities that they provide.

Bus companies: Greyhound US, FlixBus, Valley Transit and 1 more.

Airlines: United Airlines, Frontier Airlines, Skyscanner and 1 more.

All you need to know when you travel from Houston to St. Louis, MO

Check all information on comfort and services on all modes of transports from Houston to St. Louis, MO. See which seat classes are available, and what amenities are other advantages offered by the operators on your journey.

FAQs about the trip from Houston to St. Louis, MO

How can I reach St. Louis, MO from Houston?

Every day, there are on average 8 connections between Bus and Flight, with which you can get to St. Louis, MO from Houston.

How far is St. Louis, MO from Houston?

The distance between Houston and St. Louis, MO is 680.5 miles.

What is the most ecofriendly mode of transport between Houston and St. Louis, MO?

Trains and buses are by far the greenest options, with trains surpassing buses on longer routes. Planes will always be the worst polluters, especially in shorter flights, were the emissions from the takeoff and landing are less offset by the distance. On this particular route, a bus will emit, per person, a total of 30 kgs of CO2, a train 38 kgs, a car 186 kgs, and a flight 269 kgs.

What is the cheapest mode of transport from Houston to St. Louis, MO?

You can get to St. Louis, MO with just $150 by taking a Bus from Greyhound US.

What is the fastest way to get from Houston to St. Louis, MO?

While a plane is travelling fastest boarding and transfer to airport consumes a lot of time. Usually, high speed trains are better than flights if pure train travel time is below 4 hours. For this particular route, you can get to St. Louis, MO in just 2h 4m with a Flight from Skyscanner.

More routes to Houston and to St. Louis, MO

Looking for more options? Here you can see the most popular routes to Houston and to St. Louis, MO. Simply click on a connection, and you’ll find all the details about the route!

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