Which bus from Houston to St. Louis, MO is the cheapest?

Compare all bus companies and find the best price: Bus tickets from $124
Compare & Save Millions of buses in one click. Save up to 70%!
The Best Deals Save up to 70%
The Most Choices Millions of routes worldwide
Easy and Transparent Compare offers with 1 click

Compare all timetables for the bus from Houston to St. Louis, MO

Here is a selection of the cheapest bus trips from the schedule from Houston to St. Louis, MO from various bus operators like FlixBus, Greyhound US or Greyhound Lines Mexico for the next days.

today
$229
tomorrow
$158
Thursday
$143
Friday
$174
Saturday
$174
Sunday
$159
Monday
$160

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 27h 15m 7:35 PM Houston Downtown Houston 10:50 PM St. Louis, MO Gateway Station  Economy $229
Greyhound US 23h 10m 1:45 PM Houston Harrisburg Blvd Station 12:55 PM St. Louis, MO Gateway Station  Economy $229
FlixBus 27h 0m 7:50 PM Houston Uptown/Upper Kirby 10:50 PM St. Louis, MO Gateway Station  Economy $230
Greyhound US 27h 55m 6:55 PM Houston Harrisburg Blvd Station 10:50 PM St. Louis, MO Gateway Station  Economy $230
FlixBus 25h 45m 11:10 AM Houston Downtown Houston 12:55 PM St. Louis, MO Gateway Station  Economy $251
  • Did you know that if you travel from Houston to St. Louis, MO via Shreveport, LA, you can save more than $40? You can find the corresponding connections below.
    • Busbud
      32h 50m
      0
      2:10 PM
      Houston
      Harrisburg Blvd Station
      8:40 PM
      Shreveport, LA
      SporTran Intermodal Terminal
      0
      Busbud
      Economy
      $44
    • Waiting Time 4h 5m
    • Busbud
      22h 15m
      0
      12:45 AM
      Shreveport, LA
      SporTran Intermodal Terminal
      11:00 PM
      St. Louis, MO
      Gateway Station
      0
      Busbud
      Economy
      $145
    Travel time is 9h 40m longer, but you will save $40

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 27h 55m 6:55 PM Houston Harrisburg Blvd Station 10:50 PM St. Louis, MO Gateway Station  Economy $158
Greyhound US 23h 10m 1:45 PM Houston Harrisburg Blvd Station 12:55 PM St. Louis, MO Gateway Station  Economy $174
Greyhound Lines Mexico 37h 20m 9:30 AM Houston SW Agencia Autobuses 10:50 PM St. Louis, MO Gateway Station  Economy $226
FlixBus 25h 30m 11:25 AM Houston Uptown/Upper Kirby 12:55 PM St. Louis, MO Gateway Station  Economy $238
Valley Transit 30h 20m 6:35 AM Houston SW Agencia Autobuses 12:55 PM St. Louis, MO Gateway Station  Economy $241

Cheapest bus trips Thursday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 21h 0m 1:50 AM Houston Harrisburg Blvd Station 10:50 PM St. Louis, MO Gateway Station  Economy $143
Greyhound US 27h 55m 6:55 PM Houston Harrisburg Blvd Station 10:50 PM St. Louis, MO Gateway Station  Economy $143
Valley Transit 30h 20m 6:35 AM Houston SW Agencia Autobuses 12:55 PM St. Louis, MO Gateway Station  Economy $143
FlixBus 25h 55m 1:50 PM Houston Uptown/Upper Kirby 3:45 PM St. Louis, MO Gateway Station  Economy $143
FlixBus 25h 45m 11:10 AM Houston Downtown Houston 12:55 PM St. Louis, MO Gateway Station  Economy $143

Cheapest bus trips Friday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 25h 0m 10:00 PM Houston Harrisburg Blvd Station 11:00 PM St. Louis, MO Gateway Station  Economy $174
FlixBus 25h 55m 1:50 PM Houston Uptown/Upper Kirby 3:45 PM St. Louis, MO Gateway Station  Economy $175
FlixBus 22h 40m 5:05 PM Houston Downtown Houston 3:45 PM St. Louis, MO Gateway Station  Economy $176
Greyhound US 21h 0m 1:50 AM Houston Harrisburg Blvd Station 10:50 PM St. Louis, MO Gateway Station  Economy $179
Greyhound Lines Mexico 37h 20m 9:30 AM Houston SW Agencia Autobuses 10:50 PM St. Louis, MO Gateway Station  Economy $204

Cheapest bus trips Saturday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
FlixBus 22h 40m 5:05 PM Houston Downtown Houston 3:45 PM St. Louis, MO Gateway Station  Economy $174
FlixBus 25h 55m 1:50 PM Houston Uptown/Upper Kirby 3:45 PM St. Louis, MO Gateway Station  Economy $176
Greyhound US 27h 55m 6:55 PM Houston Harrisburg Blvd Station 10:50 PM St. Louis, MO Gateway Station  Economy $177
Greyhound US 21h 0m 1:50 AM Houston Harrisburg Blvd Station 10:50 PM St. Louis, MO Gateway Station  Economy $195
Valley Transit 30h 20m 6:35 AM Houston SW Agencia Autobuses 12:55 PM St. Louis, MO Gateway Station  Economy $197

Cheapest bus trips Sunday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 22h 50m 8:20 AM Houston Harrisburg Blvd Station 7:10 AM St. Louis, MO Gateway Station  Economy $159
Greyhound US 20h 50m 2:00 AM Houston Harrisburg Blvd Station 10:50 PM St. Louis, MO Gateway Station  Economy $160
FlixBus 30h 20m 6:35 AM Houston SW Agencia Autobuses 12:55 PM St. Louis, MO Gateway Station  Economy $160
FlixBus 22h 15m 8:55 AM Houston Uptown/Upper Kirby 7:10 AM St. Louis, MO Gateway Station  Economy $160
Greyhound Lines Mexico 37h 20m 9:30 AM Houston SW Agencia Autobuses 10:50 PM St. Louis, MO Gateway Station  Economy $164

Cheapest bus trips Monday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 21h 0m 1:50 AM Houston Harrisburg Blvd Station 10:50 PM St. Louis, MO Gateway Station  Economy $160
FlixBus 25h 30m 11:25 AM Houston Uptown/Upper Kirby 12:55 PM St. Louis, MO Gateway Station  Economy $162
FlixBus 27h 0m 7:50 PM Houston Uptown/Upper Kirby 10:50 PM St. Louis, MO Gateway Station  Economy $162
Greyhound US 23h 10m 1:45 PM Houston Harrisburg Blvd Station 12:55 PM St. Louis, MO Gateway Station  Economy $163
Valley Transit 30h 20m 6:35 AM Houston SW Agencia Autobuses 12:55 PM St. Louis, MO Gateway Station  Economy $184

Best Price Offer: The price for the cheapest bus from Houston to St. Louis, MO is $124 on 1/8/2026. Flexible travelers save on ticket prices.


Frequency of bus connections between Houston and St. Louis, MO

See here how frequent the connections between Houston and St. Louis, MO are, during different times and days of the week.
Sunday is the busiest day, with more than 26 daily buses from Houston to St. Louis, MO. Tuesday has instead the fewest connections, with only 12 daily coaches between Houston and St. Louis, MO.
The busiest time of the day is the Morning, with 54 buses from Houston to St. Louis, MO, while Night sees the fewest connections between Houston and St. Louis, MO, with 10 offers.

Facts about the bus from Houston to St. Louis, MO

Compare all providers like FlixBus, Greyhound US and Greyhound Lines Mexico that travel 17 times every day by bus from Houston to St. Louis, MO in one click! Book your bus ticket from Houston to St. Louis, MO starting from $124!

Cheapest Bus $124
Fastest Bus 20h 35m
Earliest Bus 11:10 AM
Latest Bus 7:50 PM
Daily Bus Routes 17 Ø
Distance 680.5 miles
Bus Companies FlixBus, Greyhound US, Greyhound Lines Mexico and Valley Transit

Cheapest bus connections from Houston to St. Louis, MO

Every day, 17 buses from 4 bus companies leave Houston for St. Louis, MO: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/16/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 12/14
Monday 12/15
Tuesday 12/16
$229
Wednesday 12/17
$158
Thursday 12/18
$143
Friday 12/19
$174
Saturday 12/20
$174
Sunday 12/21
$161
Monday 12/22
$184
Tuesday 12/23
$188
Wednesday 12/24
$177
Thursday 12/25
Friday 12/26
Saturday 12/27
$150
Sunday 12/28
$162
Monday 12/29
$160
Tuesday 12/30
Wednesday 12/31
Thursday 01/01
Friday 01/02
Saturday 01/03
Sunday 01/04
$172
Monday 01/05
$152
Tuesday 01/06
Wednesday 01/07
Thursday 01/08
$124
Friday 01/09
Saturday 01/10

The cheapest time to travel from Houston to St. Louis, MO

See here on which day and which time of the day you can find the cheapest bus ticket from Houston to St. Louis, MO, for the next 30 days.
With a price starting from $124, Thursday is the cheapest day for a bus from Houston to St. Louis, MO. Tuesday instead is the most expensive day with prices starting from $188.
Night is the cheapest day time for bus tickets from Houston to St. Louis, MO, with $124. Evening is the most expensive time of the day with prices starting from $143.

How to save money travelling from Houston to St. Louis, MO

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Houston to St. Louis, MO in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Houston to St. Louis, MO, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Houston to St. Louis, MO are also emptier.

Beloved bus companies from Houston to St. Louis, MO

These are the most booked bus companies between Houston to St. Louis, MO from our users.

All bus stations and stops in Houston and St. Louis, MO

In the map below, you can see where to find all bus stations in Houston and St. Louis, MO.

Service and Comfort on the bus from Houston to St. Louis, MO

Want to know which seat classes are available on the buses from Houston to St. Louis, MO? Or which bus companies serve the route Houston to St. Louis, MO? Below you will find answers to your questions.

FAQs about the Houston to St. Louis, MO bus

How much does a Houston St. Louis, MO bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $124 and takes 25h 55m to reach St. Louis, MO. Compare offers to save money!

How much could I save by comparing buses from Houston to St. Louis, MO?

This route is offered by 4 companies with a range of ticket prices between $124 and $263. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to St. Louis, MO.

On average, how many connections are available from Houston to St. Louis, MO each day?

Every day, the Houston to St. Louis, MO bus route is served by approximately 17 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Houston to St. Louis, MO take?

The fastest bus from Houston to St. Louis, MO is offered by FlixBus and takes 20h 35m. Bus tickets for this connection cost $167. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Houston to St. Louis, MO?

The earliest bus arriving in St. Louis, MO from Houston starts at 11:10 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Houston to St. Louis, MO?

The latest bus trip departing from Houston for St. Louis, MO starts at 7:50 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Houston St. Louis, MO route?

When traveling by bus from Houston to St. Louis, MO, passengers can travel with FlixBus, Greyhound US and Greyhound Lines Mexico. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Houston and St. Louis, MO?

You can check all the direct connections between Houston and St. Louis, MO by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus, Greyhound US and Greyhound Lines Mexico.

What can I take with me on the Houston to St. Louis, MO bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Houston St. Louis, MO bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Houston St. Louis, MO bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Houston to St. Louis, MO on your planned travel date.

How does CheckMyBus find the best bus deals from Houston to St. Louis, MO?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 17 daily trips between Houston and St. Louis, MO. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Houston to St. Louis, MO?

Prices and availability for 17 trips between Houston and St. Louis, MO change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Houston to St. Louis, MO

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Houston and to St. Louis, MO

Here’s an overview of the most popular bus routes to Houston and to St. Louis, MO. Simply click on the connection of your choice, and you will find all the details about your bus route!

The CheckMyBus App

Free Download

App Store
CheckMyBus App
Close
GPDR CheckMyBus shield

We value your privacy!

To

show

you

the

best

bus

offers,

we

and

our

partners

use

technical,

analytical,

and

marketing

cookies

to

personalize

the

ads.

We

remember

your

anonymized

details

to

provide

a

personalized

experience.