Compare all timetables for the bus from Houston to St. Louis, MO
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 27h 15m | 7:35 PM | Houston | Downtown Houston | 10:50 PM | St. Louis, MO | Gateway Station | Economy | $229 |
A Bus from FlixBus goes from Downtown Houston, Houston (USA) at 12/16/2025 7:35:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 12/17/2025 10:50:00 PM. 50 Economy ticket for $229 per person are available. Travel duration is 27h 15m
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| Greyhound US | 23h 10m | 1:45 PM | Houston | Harrisburg Blvd Station | 12:55 PM | St. Louis, MO | Gateway Station | Economy | $229 |
A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 12/16/2025 1:45:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 12/17/2025 12:55:00 PM. 50 Economy ticket for $229 per person are available. Travel duration is 23h 10m
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| FlixBus | 27h 0m | 7:50 PM | Houston | Uptown/Upper Kirby | 10:50 PM | St. Louis, MO | Gateway Station | Economy | $230 |
A Bus from FlixBus goes from Uptown/Upper Kirby, Houston (USA) at 12/16/2025 7:50:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 12/17/2025 10:50:00 PM. 50 Economy ticket for $230 per person are available. Travel duration is 27h 0m
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| Greyhound US | 27h 55m | 6:55 PM | Houston | Harrisburg Blvd Station | 10:50 PM | St. Louis, MO | Gateway Station | Economy | $230 |
A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 12/16/2025 6:55:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 12/17/2025 10:50:00 PM. 50 Economy ticket for $230 per person are available. Travel duration is 27h 55m
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| FlixBus | 25h 45m | 11:10 AM | Houston | Downtown Houston | 12:55 PM | St. Louis, MO | Gateway Station | Economy | $251 |
A Bus from FlixBus goes from Downtown Houston, Houston (USA) at 12/16/2025 11:10:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 12/17/2025 12:55:00 PM. 50 Economy ticket for $251 per person are available. Travel duration is 25h 45m
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Busbud32h 50m02:10 PMHoustonHarrisburg Blvd Station8:40 PMShreveport, LASporTran Intermodal Terminal0EconomyA Bus from Busbud goes from Harrisburg Blvd Station, Houston (USA) at 12/17/2025 2:10:00 PM to SporTran Intermodal Terminal, Shreveport, LA (USA) arriving at 12/17/2025 8:40:00 PM. 50 Economy ticket for $44 per person are available. Travel duration is 6h 30m
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Busbud22h 15m012:45 AMShreveport, LASporTran Intermodal Terminal11:00 PMSt. Louis, MOGateway Station0EconomyA Bus from Busbud goes from SporTran Intermodal Terminal, Shreveport, LA (USA) at 12/18/2025 12:45:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 12/18/2025 11:00:00 PM. 50 Economy ticket for $145 per person are available. Travel duration is 22h 15m
Waiting Time 4h 5m -
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 27h 55m | 6:55 PM | Houston | Harrisburg Blvd Station | 10:50 PM | St. Louis, MO | Gateway Station | Economy | $158 |
A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 12/17/2025 6:55:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 12/18/2025 10:50:00 PM. 50 Economy ticket for $158 per person are available. Travel duration is 27h 55m
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| Greyhound US | 23h 10m | 1:45 PM | Houston | Harrisburg Blvd Station | 12:55 PM | St. Louis, MO | Gateway Station | Economy | $174 |
A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 12/17/2025 1:45:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 12/18/2025 12:55:00 PM. 50 Economy ticket for $174 per person are available. Travel duration is 23h 10m
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| Greyhound Lines Mexico | 37h 20m | 9:30 AM | Houston | SW Agencia Autobuses | 10:50 PM | St. Louis, MO | Gateway Station | Economy | $226 |
A Bus from Greyhound Lines Mexico goes from SW Agencia Autobuses, Houston (USA) at 12/17/2025 9:30:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 12/18/2025 10:50:00 PM. 50 Economy ticket for $226 per person are available. Travel duration is 37h 20m
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| FlixBus | 25h 30m | 11:25 AM | Houston | Uptown/Upper Kirby | 12:55 PM | St. Louis, MO | Gateway Station | Economy | $238 |
A Bus from FlixBus goes from Uptown/Upper Kirby, Houston (USA) at 12/17/2025 11:25:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 12/18/2025 12:55:00 PM. 50 Economy ticket for $238 per person are available. Travel duration is 25h 30m
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| Valley Transit | 30h 20m | 6:35 AM | Houston | SW Agencia Autobuses | 12:55 PM | St. Louis, MO | Gateway Station | Economy | $241 |
A Bus from Valley Transit goes from SW Agencia Autobuses, Houston (USA) at 12/17/2025 6:35:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 12/18/2025 12:55:00 PM. 50 Economy ticket for $241 per person are available. Travel duration is 30h 20m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 21h 0m | 1:50 AM | Houston | Harrisburg Blvd Station | 10:50 PM | St. Louis, MO | Gateway Station | Economy | $143 |
A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 12/18/2025 1:50:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 12/18/2025 10:50:00 PM. 50 Economy ticket for $143 per person are available. Travel duration is 21h 0m
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| Greyhound US | 27h 55m | 6:55 PM | Houston | Harrisburg Blvd Station | 10:50 PM | St. Louis, MO | Gateway Station | Economy | $143 |
A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 12/18/2025 6:55:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 12/19/2025 10:50:00 PM. 50 Economy ticket for $143 per person are available. Travel duration is 27h 55m
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| Valley Transit | 30h 20m | 6:35 AM | Houston | SW Agencia Autobuses | 12:55 PM | St. Louis, MO | Gateway Station | Economy | $143 |
A Bus from Valley Transit goes from SW Agencia Autobuses, Houston (USA) at 12/18/2025 6:35:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 12/19/2025 12:55:00 PM. 50 Economy ticket for $143 per person are available. Travel duration is 30h 20m
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| FlixBus | 25h 55m | 1:50 PM | Houston | Uptown/Upper Kirby | 3:45 PM | St. Louis, MO | Gateway Station | Economy | $143 |
A Bus from FlixBus goes from Uptown/Upper Kirby, Houston (USA) at 12/18/2025 1:50:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 12/19/2025 3:45:00 PM. 50 Economy ticket for $143 per person are available. Travel duration is 25h 55m
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| FlixBus | 25h 45m | 11:10 AM | Houston | Downtown Houston | 12:55 PM | St. Louis, MO | Gateway Station | Economy | $143 |
A Bus from FlixBus goes from Downtown Houston, Houston (USA) at 12/18/2025 11:10:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 12/19/2025 12:55:00 PM. 50 Economy ticket for $143 per person are available. Travel duration is 25h 45m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 25h 0m | 10:00 PM | Houston | Harrisburg Blvd Station | 11:00 PM | St. Louis, MO | Gateway Station | Economy | $174 |
A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 12/19/2025 10:00:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 12/20/2025 11:00:00 PM. 50 Economy ticket for $174 per person are available. Travel duration is 25h 0m
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| FlixBus | 25h 55m | 1:50 PM | Houston | Uptown/Upper Kirby | 3:45 PM | St. Louis, MO | Gateway Station | Economy | $175 |
A Bus from FlixBus goes from Uptown/Upper Kirby, Houston (USA) at 12/19/2025 1:50:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 12/20/2025 3:45:00 PM. 50 Economy ticket for $175 per person are available. Travel duration is 25h 55m
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| FlixBus | 22h 40m | 5:05 PM | Houston | Downtown Houston | 3:45 PM | St. Louis, MO | Gateway Station | Economy | $176 |
A Bus from FlixBus goes from Downtown Houston, Houston (USA) at 12/19/2025 5:05:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 12/20/2025 3:45:00 PM. 50 Economy ticket for $176 per person are available. Travel duration is 22h 40m
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| Greyhound US | 21h 0m | 1:50 AM | Houston | Harrisburg Blvd Station | 10:50 PM | St. Louis, MO | Gateway Station | Economy | $179 |
A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 12/19/2025 1:50:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 12/19/2025 10:50:00 PM. 50 Economy ticket for $179 per person are available. Travel duration is 21h 0m
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| Greyhound Lines Mexico | 37h 20m | 9:30 AM | Houston | SW Agencia Autobuses | 10:50 PM | St. Louis, MO | Gateway Station | Economy | $204 |
A Bus from Greyhound Lines Mexico goes from SW Agencia Autobuses, Houston (USA) at 12/19/2025 9:30:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 12/20/2025 10:50:00 PM. 50 Economy ticket for $204 per person are available. Travel duration is 37h 20m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 22h 40m | 5:05 PM | Houston | Downtown Houston | 3:45 PM | St. Louis, MO | Gateway Station | Economy | $174 |
A Bus from FlixBus goes from Downtown Houston, Houston (USA) at 12/20/2025 5:05:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 12/21/2025 3:45:00 PM. 50 Economy ticket for $174 per person are available. Travel duration is 22h 40m
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| FlixBus | 25h 55m | 1:50 PM | Houston | Uptown/Upper Kirby | 3:45 PM | St. Louis, MO | Gateway Station | Economy | $176 |
A Bus from FlixBus goes from Uptown/Upper Kirby, Houston (USA) at 12/20/2025 1:50:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 12/21/2025 3:45:00 PM. 50 Economy ticket for $176 per person are available. Travel duration is 25h 55m
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| Greyhound US | 27h 55m | 6:55 PM | Houston | Harrisburg Blvd Station | 10:50 PM | St. Louis, MO | Gateway Station | Economy | $177 |
A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 12/20/2025 6:55:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 12/21/2025 10:50:00 PM. 50 Economy ticket for $177 per person are available. Travel duration is 27h 55m
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| Greyhound US | 21h 0m | 1:50 AM | Houston | Harrisburg Blvd Station | 10:50 PM | St. Louis, MO | Gateway Station | Economy | $195 |
A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 12/20/2025 1:50:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 12/20/2025 10:50:00 PM. 50 Economy ticket for $195 per person are available. Travel duration is 21h 0m
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| Valley Transit | 30h 20m | 6:35 AM | Houston | SW Agencia Autobuses | 12:55 PM | St. Louis, MO | Gateway Station | Economy | $197 |
A Bus from Valley Transit goes from SW Agencia Autobuses, Houston (USA) at 12/20/2025 6:35:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 12/21/2025 12:55:00 PM. 50 Economy ticket for $197 per person are available. Travel duration is 30h 20m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 22h 50m | 8:20 AM | Houston | Harrisburg Blvd Station | 7:10 AM | St. Louis, MO | Gateway Station | Economy | $159 |
A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 12/21/2025 8:20:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 12/22/2025 7:10:00 AM. 50 Economy ticket for $159 per person are available. Travel duration is 22h 50m
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| Greyhound US | 20h 50m | 2:00 AM | Houston | Harrisburg Blvd Station | 10:50 PM | St. Louis, MO | Gateway Station | Economy | $160 |
A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 12/21/2025 2:00:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 12/21/2025 10:50:00 PM. 50 Economy ticket for $160 per person are available. Travel duration is 20h 50m
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| FlixBus | 30h 20m | 6:35 AM | Houston | SW Agencia Autobuses | 12:55 PM | St. Louis, MO | Gateway Station | Economy | $160 |
A Bus from FlixBus goes from SW Agencia Autobuses, Houston (USA) at 12/21/2025 6:35:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 12/22/2025 12:55:00 PM. 50 Economy ticket for $160 per person are available. Travel duration is 30h 20m
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| FlixBus | 22h 15m | 8:55 AM | Houston | Uptown/Upper Kirby | 7:10 AM | St. Louis, MO | Gateway Station | Economy | $160 |
A Bus from FlixBus goes from Uptown/Upper Kirby, Houston (USA) at 12/21/2025 8:55:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 12/22/2025 7:10:00 AM. 50 Economy ticket for $160 per person are available. Travel duration is 22h 15m
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| Greyhound Lines Mexico | 37h 20m | 9:30 AM | Houston | SW Agencia Autobuses | 10:50 PM | St. Louis, MO | Gateway Station | Economy | $164 |
A Bus from Greyhound Lines Mexico goes from SW Agencia Autobuses, Houston (USA) at 12/21/2025 9:30:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 12/22/2025 10:50:00 PM. 50 Economy ticket for $164 per person are available. Travel duration is 37h 20m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 21h 0m | 1:50 AM | Houston | Harrisburg Blvd Station | 10:50 PM | St. Louis, MO | Gateway Station | Economy | $160 |
A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 12/22/2025 1:50:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 12/22/2025 10:50:00 PM. 50 Economy ticket for $160 per person are available. Travel duration is 21h 0m
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| FlixBus | 25h 30m | 11:25 AM | Houston | Uptown/Upper Kirby | 12:55 PM | St. Louis, MO | Gateway Station | Economy | $162 |
A Bus from FlixBus goes from Uptown/Upper Kirby, Houston (USA) at 12/22/2025 11:25:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 12/23/2025 12:55:00 PM. 50 Economy ticket for $162 per person are available. Travel duration is 25h 30m
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| FlixBus | 27h 0m | 7:50 PM | Houston | Uptown/Upper Kirby | 10:50 PM | St. Louis, MO | Gateway Station | Economy | $162 |
A Bus from FlixBus goes from Uptown/Upper Kirby, Houston (USA) at 12/22/2025 7:50:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 12/23/2025 10:50:00 PM. 50 Economy ticket for $162 per person are available. Travel duration is 27h 0m
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| Greyhound US | 23h 10m | 1:45 PM | Houston | Harrisburg Blvd Station | 12:55 PM | St. Louis, MO | Gateway Station | Economy | $163 |
A Bus from Greyhound US goes from Harrisburg Blvd Station, Houston (USA) at 12/22/2025 1:45:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 12/23/2025 12:55:00 PM. 50 Economy ticket for $163 per person are available. Travel duration is 23h 10m
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| Valley Transit | 30h 20m | 6:35 AM | Houston | SW Agencia Autobuses | 12:55 PM | St. Louis, MO | Gateway Station | Economy | $184 |
A Bus from Valley Transit goes from SW Agencia Autobuses, Houston (USA) at 12/22/2025 6:35:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 12/23/2025 12:55:00 PM. 50 Economy ticket for $184 per person are available. Travel duration is 30h 20m
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Best Price Offer: The price for the cheapest bus from Houston to St. Louis, MO is $124 on 1/8/2026. Flexible travelers save on ticket prices.
Frequency of bus connections between Houston and St. Louis, MO
Facts about the bus from Houston to St. Louis, MO
Compare all providers like FlixBus, Greyhound US and Greyhound Lines Mexico that travel 17 times every day by bus from Houston to St. Louis, MO in one click! Book your bus ticket from Houston to St. Louis, MO starting from $124!
| Cheapest Bus | $124 |
| Fastest Bus | 20h 35m |
| Earliest Bus | 11:10 AM |
| Latest Bus | 7:50 PM |
| Daily Bus Routes | 17 Ø |
| Distance | 680.5 miles |
| Bus Companies | FlixBus, Greyhound US, Greyhound Lines Mexico and Valley Transit |
Cheapest bus connections from Houston to St. Louis, MO
Every day, 17 buses from 4 bus companies leave Houston for St. Louis, MO: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/16/2025 and for the following days.
The cheapest time to travel from Houston to St. Louis, MO
How to save money travelling from Houston to St. Louis, MO
Book the ticket from Houston to St. Louis, MO in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Houston to St. Louis, MO, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Houston to St. Louis, MO are also emptier.Beloved bus companies from Houston to St. Louis, MO
Greyhound Lines Mexico from Houston to St. Louis, MO
Here you will find the key facts about the Greyhound Lines Mexico bus route Houston to St. Louis, MO:
| Cheapest Price | $145 |
| Fastest Bus | 37h 20m |
| Earliest Bus | 9:30 AM |
| Last Bus | 9:30 AM |
| Daily Connections | 1 Ø |
| Found on | 12/15/2025 |
All bus stations and stops in Houston and St. Louis, MO
In the map below, you can see where to find all bus stations in Houston and St. Louis, MO.
Service and Comfort on the bus from Houston to St. Louis, MO
FAQs about the Houston to St. Louis, MO bus
How much does a Houston St. Louis, MO bus trip cost?
How much could I save by comparing buses from Houston to St. Louis, MO?
On average, how many connections are available from Houston to St. Louis, MO each day?
How long does a bus journey from Houston to St. Louis, MO take?
What time is the first bus from Houston to St. Louis, MO?
What time is the last bus from Houston to St. Louis, MO?
Which bus companies operate the Houston St. Louis, MO route?
Is there a direct bus between Houston and St. Louis, MO?
What can I take with me on the Houston to St. Louis, MO bus route?
What equipment is available for the Houston St. Louis, MO bus route?
How does CheckMyBus find the best bus deals from Houston to St. Louis, MO?
How does CheckMyBus technology work for trips from Houston to St. Louis, MO?
Available seat classes which are offered on the bus route Houston to St. Louis, MO
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
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