Bus from Houston to St. Louis, MO from $120

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Compare all timetables for the bus from Houston to St. Louis, MO

Here is a selection of the cheapest bus trips from the schedule from Houston to St. Louis, MO from various bus operators like FlixBus, Greyhound US or Greyhound Lines Mexico for the next days.

today
from $154
tomorrow
from $120
Tuesday
from $173
Wednesday
from $139
Thursday
from $122
Friday
Saturday
from $125

Cheapest bus trips today

Prices are for one way and one person
  • FlixBus
    22h 45m
    0
    5:00 PM
    Houston
    Downtown Houston
    3:45 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $154
  • FlixBus
    23h 55m
    0
    7:10 AM
    Houston
    Uptown/Upper Kirby
    7:05 AM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $158
  • Greyhound US
    22h 45m
    0
    8:20 AM
    Houston
    Harrisburg Blvd Station
    7:05 AM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $159
  • Greyhound US
    27h 40m
    0
    7:00 PM
    Houston
    Harrisburg Blvd Station
    10:40 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $172
  • Greyhound Lines Mexico
    36h 35m
    0
    10:05 AM
    Houston
    SW Agencia Autobuses
    10:40 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound Lines Mexico
    Economy
    $177

Cheapest bus trips tomorrow

Prices are for one way and one person
  • FlixBus
    26h 30m
    0
    1:15 PM
    Houston
    Uptown/Upper Kirby
    3:45 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $120
  • FlixBus
    22h 45m
    0
    5:00 PM
    Houston
    Downtown Houston
    3:45 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $122
  • Greyhound US
    25h 45m
    0
    2:10 PM
    Houston
    Harrisburg Blvd Station
    3:55 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $124
  • Greyhound US
    25h 45m
    0
    2:10 PM
    Houston
    Harrisburg Blvd Station
    3:55 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $127
  • Greyhound Lines Mexico
    36h 35m
    0
    10:05 AM
    Houston
    SW Agencia Autobuses
    10:40 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound Lines Mexico
    Economy
    $138

Cheapest bus trips Tuesday

Prices are for one way and one person
  • Greyhound US
    20h 40m
    0
    2:00 AM
    Houston
    Harrisburg Blvd Station
    10:40 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $173
  • Greyhound US
    27h 40m
    0
    7:00 PM
    Houston
    Harrisburg Blvd Station
    10:40 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $181
  • Greyhound Lines Mexico
    36h 35m
    0
    10:05 AM
    Houston
    SW Agencia Autobuses
    10:40 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound Lines Mexico
    Economy
    $181
  • FlixBus
    25h 30m
    0
    11:25 AM
    Houston
    Uptown/Upper Kirby
    12:55 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $194
  • Valley Transit
    30h 20m
    0
    6:35 AM
    Houston
    SW Agencia Autobuses
    12:55 PM
    St. Louis, MO
    Gateway Station
    0
    Valley Transit
    Economy
    $196

Cheapest bus trips Wednesday

Prices are for one way and one person
  • Greyhound US
    25h 45m
    0
    2:10 PM
    Houston
    Harrisburg Blvd Station
    3:55 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $139
  • Greyhound US
    20h 40m
    0
    2:00 AM
    Houston
    Harrisburg Blvd Station
    10:40 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $142
  • Greyhound Lines Mexico
    36h 35m
    0
    10:05 AM
    Houston
    SW Agencia Autobuses
    10:40 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound Lines Mexico
    Economy
    $152
  • FlixBus
    25h 45m
    0
    11:10 AM
    Houston
    Downtown Houston
    12:55 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $164
  • FlixBus
    25h 30m
    0
    11:25 AM
    Houston
    Uptown/Upper Kirby
    12:55 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $165

Cheapest bus trips Thursday

Prices are for one way and one person
  • FlixBus
    25h 45m
    0
    2:00 PM
    Houston
    Uptown/Upper Kirby
    3:45 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $122
  • FlixBus
    22h 45m
    0
    5:00 PM
    Houston
    Downtown Houston
    3:45 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $122
  • Greyhound US
    22h 45m
    0
    8:20 AM
    Houston
    Harrisburg Blvd Station
    7:05 AM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $123
  • Greyhound US
    20h 40m
    0
    2:00 AM
    Houston
    Harrisburg Blvd Station
    10:40 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $134
  • Greyhound Lines Mexico
    36h 35m
    0
    10:05 AM
    Houston
    SW Agencia Autobuses
    10:40 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound Lines Mexico
    Economy
    $141

Cheapest bus trips Saturday

Prices are for one way and one person
  • FlixBus
    22h 45m
    0
    5:00 PM
    Houston
    Downtown Houston
    3:45 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $125
  • Greyhound US
    22h 45m
    0
    8:20 AM
    Houston
    Harrisburg Blvd Station
    7:05 AM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $126
  • FlixBus
    25h 45m
    0
    2:00 PM
    Houston
    Uptown/Upper Kirby
    3:45 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $126
  • Greyhound US
    25h 45m
    0
    2:10 PM
    Houston
    Harrisburg Blvd Station
    3:55 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $127
  • Greyhound Lines Mexico
    36h 35m
    0
    10:05 AM
    Houston
    SW Agencia Autobuses
    10:40 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound Lines Mexico
    Economy
    $144

Frequency of bus connections between Houston and St. Louis, MO

See here how frequent the connections between Houston and St. Louis, MO are, during different times and days of the week.
Monday is the busiest day, with more than 30 daily buses from Houston to St. Louis, MO. Sunday has instead the fewest connections, with only 14 daily coaches between Houston and St. Louis, MO.
The busiest time of the day is the Morning, with 51 buses from Houston to St. Louis, MO, while Night sees the fewest connections between Houston and St. Louis, MO, with 12 offers.

Facts about the bus from Houston to St. Louis, MO

Compare all providers like FlixBus, Greyhound US and Greyhound Lines Mexico that travel 22 times every day by bus from Houston to St. Louis, MO in one click! Book your bus ticket from Houston to St. Louis, MO starting from $120!

Cheapest Bus $120
Fastest Bus 20h 10m
Earliest Bus 2:00 AM
Latest Bus 7:50 PM
Daily Bus Routes 22 Ø
Distance 680.5 miles
Bus Companies FlixBus, Greyhound US, Greyhound Lines Mexico and Valley Transit

Cheapest bus connections from Houston to St. Louis, MO

Every day, 22 buses from 4 bus companies leave Houston for St. Louis, MO: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 06/30/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 06/29
$154
Monday 06/30
$123
Tuesday 07/01
$173
Wednesday 07/02
$166
Thursday 07/03
$122
Friday 07/04
Saturday 07/05
$165
Sunday 07/06
$179
Monday 07/07
Tuesday 07/08
Wednesday 07/09
$117
Thursday 07/10
$131
Friday 07/11
$89
Saturday 07/12
Sunday 07/13
Monday 07/14
$115
Tuesday 07/15
$140
Wednesday 07/16
Thursday 07/17
$107
Friday 07/18
Saturday 07/19
$115
Sunday 07/20
$138
Monday 07/21
$149
Tuesday 07/22
Wednesday 07/23
Thursday 07/24
Friday 07/25
$129
Saturday 07/26

The cheapest time to travel from Houston to St. Louis, MO

See here on which day and which time of the day you can find the cheapest bus ticket from Houston to St. Louis, MO, for the next 30 days.
With a price starting from $120, Monday is the cheapest day for a bus from Houston to St. Louis, MO. Tuesday instead is the most expensive day with prices starting from $173.
Afternoon is the cheapest day time for bus tickets from Houston to St. Louis, MO, with $120. Evening is the most expensive time of the day with prices starting from $134.

How to save money travelling from Houston to St. Louis, MO

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Houston to St. Louis, MO in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Houston to St. Louis, MO, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Houston to St. Louis, MO are also emptier.

Beloved bus companies from Houston to St. Louis, MO

These are the most booked bus companies between Houston to St. Louis, MO from our users.

Greyhound US from Houston to St. Louis, MO

Greyhound US

Here you will find the key facts about the Greyhound US bus route Houston to St. Louis, MO:

Cheapest Price $123
Fastest Bus 20h 10m
Earliest Bus 2:00 AM
Last Bus 7:00 PM
Daily Connections 7 Ø
Found on 6/26/2025

All bus stations and stops in Houston and St. Louis, MO

In the map below, you can see where to find all bus stations in Houston and St. Louis, MO.

Service and Comfort on the bus from Houston to St. Louis, MO

Want to know which seat classes are available on the buses from Houston to St. Louis, MO? Or which bus companies serve the route Houston to St. Louis, MO? Below you will find answers to your questions.

FAQs about the Houston to St. Louis, MO bus

How much does a Houston St. Louis, MO bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $120 and takes 26h 30m to reach St. Louis, MO. Compare offers to save money!

How much could I save by comparing buses from Houston to St. Louis, MO?

This route is offered by 4 companies with a range of ticket prices between $120 and $269. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to St. Louis, MO.

On average, how many connections are available from Houston to St. Louis, MO each day?

Every day, the Houston to St. Louis, MO bus route is served by approximately 22 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Houston to St. Louis, MO take?

The fastest bus from Houston to St. Louis, MO is offered by Greyhound US and takes 20h 10m. Bus tickets for this connection cost $151. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Houston to St. Louis, MO?

The earliest bus arriving in St. Louis, MO from Houston starts at 2:00 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Houston to St. Louis, MO?

The latest bus trip departing from Houston for St. Louis, MO starts at 7:50 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Houston St. Louis, MO route?

When traveling by bus from Houston to St. Louis, MO, passengers can travel with FlixBus, Greyhound US and Greyhound Lines Mexico. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Houston and St. Louis, MO?

You can check all the direct connections between Houston and St. Louis, MO by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus, Greyhound US and Greyhound Lines Mexico.

What can I take with me on the Houston to St. Louis, MO bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Houston St. Louis, MO bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Houston St. Louis, MO bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Houston to St. Louis, MO on your planned travel date.

Available seat classes which are offered on the bus route Houston to St. Louis, MO

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Houston and to St. Louis, MO

Here’s an overview of the most popular bus routes to Houston and to St. Louis, MO. Simply click on the connection of your choice, and you will find all the details about your bus route!
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