Bus from Houston to St. Louis, MO from $110

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Compare all timetables for the bus from Houston to St. Louis, MO

Here is a selection of the cheapest bus trips from the schedule from Houston to St. Louis, MO from various bus operators like FlixBus, Greyhound US or Greyhound Lines Mexico for the next days.
today
from $122
tomorrow
from $110
Friday
from $136
Saturday
from $137
Sunday
Monday
from $129
Tuesday
from $116

Cheapest bus trips today

Prices are for one way and one person
  • Greyhound Lines Mexico
    36h 35m
    0
    10:05 AM
    Houston
    SW Agencia Autobuses
    10:40 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound Lines Mexico
    Economy
    $122
  • Greyhound Lines Mexico
    36h 5m
    0
    10:05 AM
    Houston
    SW Agencia Autobuses
    10:10 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound Lines Mexico
    Economy
    $122
  • Greyhound US
    25h 45m
    0
    2:10 PM
    Houston
    Harrisburg Blvd Station
    3:55 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $123
  • Greyhound US
    27h 10m
    0
    7:00 PM
    Houston
    Harrisburg Blvd Station
    10:10 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $123
  • FlixBus
    35h 0m
    0
    11:10 AM
    Houston
    Downtown Houston
    10:10 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $123

Cheapest bus trips tomorrow

Prices are for one way and one person
  • Greyhound US
    20h 40m
    0
    2:00 AM
    Houston
    Harrisburg Blvd Station
    10:40 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $110
  • FlixBus
    31h 35m
    0
    2:35 PM
    Houston
    Downtown Houston
    10:10 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $110
  • FlixBus
    31h 20m
    0
    2:50 PM
    Houston
    Uptown/Upper Kirby
    10:10 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $110
  • Greyhound Lines Mexico
    36h 5m
    0
    10:05 AM
    Houston
    SW Agencia Autobuses
    10:10 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound Lines Mexico
    Economy
    $110
  • Greyhound US
    20h 10m
    0
    2:00 AM
    Houston
    Harrisburg Blvd Station
    10:10 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $111

Cheapest bus trips Friday

Prices are for one way and one person
  • Greyhound US
    25h 45m
    0
    2:10 PM
    Houston
    Harrisburg Blvd Station
    3:55 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $136
  • Greyhound US
    27h 40m
    0
    7:00 PM
    Houston
    Harrisburg Blvd Station
    10:40 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $136
  • Greyhound Lines Mexico
    36h 35m
    0
    10:05 AM
    Houston
    SW Agencia Autobuses
    10:40 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound Lines Mexico
    Economy
    $137
  • Greyhound Lines Mexico
    36h 5m
    0
    10:05 AM
    Houston
    SW Agencia Autobuses
    10:10 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound Lines Mexico
    Economy
    $137
  • FlixBus
    25h 45m
    0
    2:00 PM
    Houston
    Uptown/Upper Kirby
    3:45 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $137

Cheapest bus trips Saturday

Prices are for one way and one person
  • Greyhound US
    23h 10m
    0
    1:45 PM
    Houston
    Harrisburg Blvd Station
    12:55 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $137
  • FlixBus
    25h 45m
    0
    2:00 PM
    Houston
    Uptown/Upper Kirby
    3:45 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $137
  • FlixBus
    23h 25m
    0
    1:30 PM
    Houston
    Downtown Houston
    12:55 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $137
  • Greyhound US
    20h 40m
    0
    2:00 AM
    Houston
    Harrisburg Blvd Station
    10:40 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $138
  • Greyhound Lines Mexico
    36h 35m
    0
    10:05 AM
    Houston
    SW Agencia Autobuses
    10:40 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound Lines Mexico
    Economy
    $151

Cheapest bus trips Monday

Prices are for one way and one person
  • FlixBus
    22h 45m
    0
    5:00 PM
    Houston
    Downtown Houston
    3:45 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $129
  • Greyhound US
    25h 45m
    0
    2:10 PM
    Houston
    Harrisburg Blvd Station
    3:55 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $130
  • FlixBus
    26h 30m
    0
    1:15 PM
    Houston
    Uptown/Upper Kirby
    3:45 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $130
  • Greyhound US
    27h 40m
    0
    7:00 PM
    Houston
    Harrisburg Blvd Station
    10:40 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $133
  • Greyhound Lines Mexico
    36h 35m
    0
    10:05 AM
    Houston
    SW Agencia Autobuses
    10:40 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound Lines Mexico
    Economy
    $139
  • Did you know that if you travel from Houston to St. Louis, MO via Dallas, you can save more than $16? You can find the corresponding connections below.
    • Busbud
      30h 55m
      0
      3:15 PM
      Houston
      Main St & Airline Dr
      7:30 PM
      Dallas
      Downtown
      0
      Busbud
      Economy
      $26
      • Waiting Time 11h 50m
    • Busbud
      14h 50m
      0
      7:20 AM
      Dallas
      Bus Station
      10:10 PM
      St. Louis, MO
      Gateway Station
      0
      Busbud
      Economy
      $87
    Travel time is 8h 10m longer, but you will save $16

Cheapest bus trips Tuesday

Prices are for one way and one person
  • FlixBus
    22h 45m
    0
    1:30 PM
    Houston
    Downtown Houston
    12:15 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $116
  • FlixBus
    22h 30m
    0
    1:45 PM
    Houston
    Main St & Airline Dr
    12:15 PM
    St. Louis, MO
    Gateway Station
    0
    FlixBus
    Economy
    $116
  • Greyhound US
    20h 10m
    0
    2:00 AM
    Houston
    Harrisburg Blvd Station
    10:10 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $117
  • Greyhound US
    27h 40m
    0
    7:00 PM
    Houston
    Harrisburg Blvd Station
    10:40 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound US
    Economy
    $117
  • Greyhound Lines Mexico
    36h 35m
    0
    10:05 AM
    Houston
    SW Agencia Autobuses
    10:40 PM
    St. Louis, MO
    Gateway Station
    0
    Greyhound Lines Mexico
    Economy
    $117

Frequency of bus connections between Houston and St. Louis, MO

See here how frequent the connections between Houston and St. Louis, MO are, during different times and days of the week.
Tuesday is the busiest day, with more than 24 daily buses from Houston to St. Louis, MO. Saturday has instead the fewest connections, with only 12 daily coaches between Houston and St. Louis, MO.
The busiest time of the day is the Afternoon, with 38 buses from Houston to St. Louis, MO, while Night sees the fewest connections between Houston and St. Louis, MO, with 13 offers.

Facts about the bus from Houston to St. Louis, MO

Compare all providers like FlixBus, Greyhound US and Greyhound Lines Mexico that travel 18 times every day by bus from Houston to St. Louis, MO in one click! Book your bus ticket from Houston to St. Louis, MO starting from $110!

Cheapest Bus $110
Fastest Bus 20h 10m
Earliest Bus 2:00 AM
Latest Bus 7:50 PM
Daily Bus Routes 18 Ø
Distance 680.5 miles
Bus Companies FlixBus, Greyhound US and Greyhound Lines Mexico

Cheapest bus connections from Houston to St. Louis, MO

Every day, 18 buses from 3 bus companies leave Houston for St. Louis, MO: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 05/14/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 05/11
Monday 05/12
Tuesday 05/13
Wednesday 05/14
$122
Thursday 05/15
$124
Friday 05/16
$136
Saturday 05/17
$137
Sunday 05/18
Monday 05/19
$129
Tuesday 05/20
$116
Wednesday 05/21
$125
Thursday 05/22
$126
Friday 05/23
Saturday 05/24
$101
Sunday 05/25
$110
Monday 05/26
Tuesday 05/27
Wednesday 05/28
Thursday 05/29
Friday 05/30
Saturday 05/31
Sunday 06/01
$93
Monday 06/02
$97
Tuesday 06/03
Wednesday 06/04
Thursday 06/05
$96
Friday 06/06
Saturday 06/07

The cheapest time to travel from Houston to St. Louis, MO

See here on which day and which time of the day you can find the cheapest bus ticket from Houston to St. Louis, MO, for the next 30 days.
With a price starting from $110, Thursday is the cheapest day for a bus from Houston to St. Louis, MO. Saturday instead is the most expensive day with prices starting from $137.
Afternoon is the cheapest day time for bus tickets from Houston to St. Louis, MO, with $110. Evening is the most expensive time of the day with prices starting from $111.

How to save money travelling from Houston to St. Louis, MO

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Houston to St. Louis, MO in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Houston to St. Louis, MO, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Houston to St. Louis, MO are also emptier.

All bus stations and stops in Houston and St. Louis, MO

In the map below, you can see where to find all bus stations in Houston and St. Louis, MO.

Service and Comfort on the bus from Houston to St. Louis, MO

Want to know which seat classes are available on the buses from Houston to St. Louis, MO? Or which bus companies serve the route Houston to St. Louis, MO? Below you will find answers to your questions.

FAQs about the Houston to St. Louis, MO bus

How much does a Houston St. Louis, MO bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $110 and takes 31h 35m to reach St. Louis, MO. Compare offers to save money!

How much could I save by comparing buses from Houston to St. Louis, MO?

This route is offered by 3 companies with a range of ticket prices between $110 and $186. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to St. Louis, MO.

On average, how many connections are available from Houston to St. Louis, MO each day?

Every day, the Houston to St. Louis, MO bus route is served by approximately 18 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Houston to St. Louis, MO take?

The fastest bus from Houston to St. Louis, MO is offered by Greyhound US and takes 20h 10m. Bus tickets for this connection cost $124. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Houston to St. Louis, MO?

The earliest bus arriving in St. Louis, MO from Houston starts at 2:00 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Houston to St. Louis, MO?

The latest bus trip departing from Houston for St. Louis, MO starts at 7:50 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Houston St. Louis, MO route?

When traveling by bus from Houston to St. Louis, MO, passengers can travel with FlixBus, Greyhound US and Greyhound Lines Mexico. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Houston and St. Louis, MO?

You can check all the direct connections between Houston and St. Louis, MO by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus, Greyhound US and Greyhound Lines Mexico.

What can I take with me on the Houston to St. Louis, MO bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Houston St. Louis, MO bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Houston St. Louis, MO bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Houston to St. Louis, MO on your planned travel date.

Available seat classes which are offered on the bus route Houston to St. Louis, MO

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Houston and to St. Louis, MO

Here’s an overview of the most popular bus routes to Houston and to St. Louis, MO. Simply click on the connection of your choice, and you will find all the details about your bus route!
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Popular Airport Shuttles to Houston and to St. Louis, MO
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