Bus Charlotte to St. Louis, MO - Compare all Companies

Compare all timetables for the bus from Charlotte to St. Louis, MO

Here is a selection of the cheapest bus trips from the schedule from Charlotte to St. Louis, MO from various bus operators like FlixBus or Greyhound US for the next days.

today

$124

tomorrow

$113

Sunday

$103

Monday

$113

Tuesday

$104

Wednesday

Thursday

$103

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	16h 30m	5:40 PM	Charlotte	W Trade St	9:10 AM	St. Louis, MO	Gateway Station	Economy	$124	A Bus from FlixBus goes from W Trade St, Charlotte (USA) at 12/5/2025 5:40:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 12/6/2025 9:10:00 AM. 50 Economy ticket for $124 per person are available. Travel duration is 16h 30m
Greyhound US	18h 25m	10:30 PM	Charlotte	W Trade St	3:55 PM	St. Louis, MO	Gateway Station	Economy	$124	A Bus from Greyhound US goes from W Trade St, Charlotte (USA) at 12/5/2025 10:30:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 12/6/2025 3:55:00 PM. 50 Economy ticket for $124 per person are available. Travel duration is 18h 25m
FlixBus	23h 5m	12:55 AM	Charlotte	W Trade St	11:00 PM	St. Louis, MO	Gateway Station	Economy	$125	A Bus from FlixBus goes from W Trade St, Charlotte (USA) at 12/5/2025 12:55:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 12/5/2025 11:00:00 PM. 50 Economy ticket for $125 per person are available. Travel duration is 23h 5m
FlixBus	31h 45m	11:40 PM	Charlotte	Freedom Drive 3301	6:25 AM	St. Louis, MO	Gateway Station	Economy	$125	A Bus from FlixBus goes from Freedom Drive 3301, Charlotte (USA) at 12/5/2025 11:40:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 12/7/2025 6:25:00 AM. 50 Economy ticket for $125 per person are available. Travel duration is 31h 45m
Greyhound US	21h 35m	2:50 AM	Charlotte	W Trade St	11:25 PM	St. Louis, MO	Gateway Station	Economy	$126	A Bus from Greyhound US goes from W Trade St, Charlotte (USA) at 12/5/2025 2:50:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 12/5/2025 11:25:00 PM. 50 Economy ticket for $126 per person are available. Travel duration is 21h 35m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	16h 30m	5:40 PM	Charlotte	W Trade St	9:10 AM	St. Louis, MO	Gateway Station	Economy	$113	A Bus from FlixBus goes from W Trade St, Charlotte (USA) at 12/6/2025 5:40:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 12/7/2025 9:10:00 AM. 50 Economy ticket for $113 per person are available. Travel duration is 16h 30m
FlixBus	27h 15m	6:55 AM	Charlotte	Freedom Drive 3301	9:10 AM	St. Louis, MO	Gateway Station	Economy	$113	A Bus from FlixBus goes from Freedom Drive 3301, Charlotte (USA) at 12/6/2025 6:55:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 12/7/2025 9:10:00 AM. 50 Economy ticket for $113 per person are available. Travel duration is 27h 15m
Greyhound US	22h 35m	6:10 PM	Charlotte	W Trade St	3:45 PM	St. Louis, MO	Gateway Station	Economy	$113	A Bus from Greyhound US goes from W Trade St, Charlotte (USA) at 12/6/2025 6:10:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 12/7/2025 3:45:00 PM. 50 Economy ticket for $113 per person are available. Travel duration is 22h 35m
Greyhound US	21h 35m	2:50 AM	Charlotte	W Trade St	11:25 PM	St. Louis, MO	Gateway Station	Economy	$114	A Bus from Greyhound US goes from W Trade St, Charlotte (USA) at 12/6/2025 2:50:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 12/6/2025 11:25:00 PM. 50 Economy ticket for $114 per person are available. Travel duration is 21h 35m
Greyhound US	18h 25m	10:30 PM	Charlotte	W Trade St	3:55 PM	St. Louis, MO	Gateway Station	Economy	$114	A Bus from Greyhound US goes from W Trade St, Charlotte (USA) at 12/6/2025 10:30:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 12/7/2025 3:55:00 PM. 50 Economy ticket for $114 per person are available. Travel duration is 18h 25m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	16h 30m	5:40 PM	Charlotte	W Trade St	9:10 AM	St. Louis, MO	Gateway Station	Economy	$103	A Bus from FlixBus goes from W Trade St, Charlotte (USA) at 12/7/2025 5:40:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 12/8/2025 9:10:00 AM. 50 Economy ticket for $103 per person are available. Travel duration is 16h 30m
Greyhound US	22h 35m	6:10 PM	Charlotte	W Trade St	3:45 PM	St. Louis, MO	Gateway Station	Economy	$103	A Bus from Greyhound US goes from W Trade St, Charlotte (USA) at 12/7/2025 6:10:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 12/8/2025 3:45:00 PM. 50 Economy ticket for $103 per person are available. Travel duration is 22h 35m
FlixBus	30h 20m	6:05 PM	Charlotte	Freedom Drive 3301	11:25 PM	St. Louis, MO	Gateway Station	Economy	$104	A Bus from FlixBus goes from Freedom Drive 3301, Charlotte (USA) at 12/7/2025 6:05:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 12/8/2025 11:25:00 PM. 50 Economy ticket for $104 per person are available. Travel duration is 30h 20m
FlixBus	31h 45m	11:40 PM	Charlotte	Freedom Drive 3301	6:25 AM	St. Louis, MO	Gateway Station	Economy	$104	A Bus from FlixBus goes from Freedom Drive 3301, Charlotte (USA) at 12/7/2025 11:40:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 12/9/2025 6:25:00 AM. 50 Economy ticket for $104 per person are available. Travel duration is 31h 45m
Greyhound US	21h 35m	2:50 AM	Charlotte	W Trade St	11:25 PM	St. Louis, MO	Gateway Station	Economy	$104	A Bus from Greyhound US goes from W Trade St, Charlotte (USA) at 12/7/2025 2:50:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 12/7/2025 11:25:00 PM. 50 Economy ticket for $104 per person are available. Travel duration is 21h 35m

Cheapest bus trips Monday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	30h 20m	6:05 PM	Charlotte	Freedom Drive 3301	11:25 PM	St. Louis, MO	Gateway Station	Economy	$113	A Bus from FlixBus goes from Freedom Drive 3301, Charlotte (USA) at 12/8/2025 6:05:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 12/9/2025 11:25:00 PM. 50 Economy ticket for $113 per person are available. Travel duration is 30h 20m
Greyhound US	21h 35m	2:50 AM	Charlotte	W Trade St	11:25 PM	St. Louis, MO	Gateway Station	Economy	$113	A Bus from Greyhound US goes from W Trade St, Charlotte (USA) at 12/8/2025 2:50:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 12/8/2025 11:25:00 PM. 50 Economy ticket for $113 per person are available. Travel duration is 21h 35m
Greyhound US	18h 25m	10:30 PM	Charlotte	W Trade St	3:55 PM	St. Louis, MO	Gateway Station	Economy	$113	A Bus from Greyhound US goes from W Trade St, Charlotte (USA) at 12/8/2025 10:30:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 12/9/2025 3:55:00 PM. 50 Economy ticket for $113 per person are available. Travel duration is 18h 25m
FlixBus	23h 5m	12:55 AM	Charlotte	W Trade St	11:00 PM	St. Louis, MO	Gateway Station	Economy	$114	A Bus from FlixBus goes from W Trade St, Charlotte (USA) at 12/8/2025 12:55:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 12/8/2025 11:00:00 PM. 50 Economy ticket for $114 per person are available. Travel duration is 23h 5m
FlixBus	31h 45m	11:40 PM	Charlotte	Freedom Drive 3301	6:25 AM	St. Louis, MO	Gateway Station	Economy	$114	A Bus from FlixBus goes from Freedom Drive 3301, Charlotte (USA) at 12/8/2025 11:40:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 12/10/2025 6:25:00 AM. 50 Economy ticket for $114 per person are available. Travel duration is 31h 45m

Cheapest bus trips Tuesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	21h 35m	2:50 AM	Charlotte	W Trade St	11:25 PM	St. Louis, MO	Gateway Station	Economy	$104	A Bus from Greyhound US goes from W Trade St, Charlotte (USA) at 12/9/2025 2:50:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 12/9/2025 11:25:00 PM. 50 Economy ticket for $104 per person are available. Travel duration is 21h 35m
Greyhound US	27h 30m	12:50 PM	Charlotte	W Trade St	3:20 PM	St. Louis, MO	Gateway Station	Economy	$104	A Bus from Greyhound US goes from W Trade St, Charlotte (USA) at 12/9/2025 12:50:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 12/10/2025 3:20:00 PM. 50 Economy ticket for $104 per person are available. Travel duration is 27h 30m
FlixBus	23h 5m	12:55 AM	Charlotte	W Trade St	11:00 PM	St. Louis, MO	Gateway Station	Economy	$105	A Bus from FlixBus goes from W Trade St, Charlotte (USA) at 12/9/2025 12:55:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 12/9/2025 11:00:00 PM. 50 Economy ticket for $105 per person are available. Travel duration is 23h 5m
Greyhound US	18h 25m	10:30 PM	Charlotte	W Trade St	3:55 PM	St. Louis, MO	Gateway Station	Economy	$105	A Bus from Greyhound US goes from W Trade St, Charlotte (USA) at 12/9/2025 10:30:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 12/10/2025 3:55:00 PM. 50 Economy ticket for $105 per person are available. Travel duration is 18h 25m
FlixBus	31h 45m	11:40 PM	Charlotte	Freedom Drive 3301	6:25 AM	St. Louis, MO	Gateway Station	Economy	$106	A Bus from FlixBus goes from Freedom Drive 3301, Charlotte (USA) at 12/9/2025 11:40:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 12/11/2025 6:25:00 AM. 50 Economy ticket for $106 per person are available. Travel duration is 31h 45m

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	21h 20m	12:50 PM	Charlotte	W Trade St	9:10 AM	St. Louis, MO	Gateway Station	Economy	$103	A Bus from Greyhound US goes from W Trade St, Charlotte (USA) at 12/11/2025 12:50:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 12/12/2025 9:10:00 AM. 50 Economy ticket for $103 per person are available. Travel duration is 21h 20m
Greyhound US	22h 35m	6:10 PM	Charlotte	W Trade St	3:45 PM	St. Louis, MO	Gateway Station	Economy	$103	A Bus from Greyhound US goes from W Trade St, Charlotte (USA) at 12/11/2025 6:10:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 12/12/2025 3:45:00 PM. 50 Economy ticket for $103 per person are available. Travel duration is 22h 35m
FlixBus	27h 15m	6:55 AM	Charlotte	Freedom Drive 3301	9:10 AM	St. Louis, MO	Gateway Station	Economy	$103	A Bus from FlixBus goes from Freedom Drive 3301, Charlotte (USA) at 12/11/2025 6:55:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 12/12/2025 9:10:00 AM. 50 Economy ticket for $103 per person are available. Travel duration is 27h 15m
Greyhound US	21h 35m	2:50 AM	Charlotte	W Trade St	11:25 PM	St. Louis, MO	Gateway Station	Economy	$104	A Bus from Greyhound US goes from W Trade St, Charlotte (USA) at 12/11/2025 2:50:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 12/11/2025 11:25:00 PM. 50 Economy ticket for $104 per person are available. Travel duration is 21h 35m
FlixBus	30h 20m	6:05 PM	Charlotte	Freedom Drive 3301	11:25 PM	St. Louis, MO	Gateway Station	Economy	$104	A Bus from FlixBus goes from Freedom Drive 3301, Charlotte (USA) at 12/11/2025 6:05:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 12/12/2025 11:25:00 PM. 50 Economy ticket for $104 per person are available. Travel duration is 30h 20m

Best Price Offer: The price for the cheapest bus from Charlotte to St. Louis, MO is $83 on 12/12/2025. Flexible travelers save on ticket prices.

Frequency of bus connections between Charlotte and St. Louis, MO

See here how frequent the connections between Charlotte and St. Louis, MO are, during different times and days of the week.

Sunday is the busiest day, with more than 16 daily buses from Charlotte to St. Louis, MO. Friday has instead the fewest connections, with only 8 daily coaches between Charlotte and St. Louis, MO.

The busiest time of the day is the Evening, with 40 buses from Charlotte to St. Louis, MO, while Morning sees the fewest connections between Charlotte and St. Louis, MO, with 9 offers.

Facts about the bus from Charlotte to St. Louis, MO

Compare all providers like FlixBus and Greyhound US that travel 13 times every day by bus from Charlotte to St. Louis, MO in one click! Book your bus ticket from Charlotte to St. Louis, MO starting from $83!

Cheapest Bus	$83
Fastest Bus	15h 30m
Earliest Bus	12:55 AM
Latest Bus	11:40 PM
Daily Bus Routes	13 Ø
Distance	567.1 miles
Bus Companies	FlixBus and Greyhound US

Cheapest bus connections from Charlotte to St. Louis, MO

Every day, 13 buses from 2 bus companies leave Charlotte for St. Louis, MO: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 12/05/2025 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 11/30

Monday 12/01

Tuesday 12/02

Wednesday 12/03

Thursday 12/04

Friday 12/05

$124

Saturday 12/06

$113

Sunday 12/07

$103

Monday 12/08

$117

Tuesday 12/09

$104

Wednesday 12/10

Thursday 12/11

$103

Friday 12/12

$83

Saturday 12/13

Sunday 12/14

Monday 12/15

$118

Tuesday 12/16

$109

Wednesday 12/17

Thursday 12/18

Friday 12/19

Saturday 12/20

Sunday 12/21

Monday 12/22

Tuesday 12/23

Wednesday 12/24

Thursday 12/25

Friday 12/26

Saturday 12/27

The cheapest time to travel from Charlotte to St. Louis, MO

See here on which day and which time of the day you can find the cheapest bus ticket from Charlotte to St. Louis, MO, for the next 30 days.

With a price starting from $83, Friday is the cheapest day for a bus from Charlotte to St. Louis, MO. Saturday instead is the most expensive day with prices starting from $113.

Night is the cheapest day time for bus tickets from Charlotte to St. Louis, MO, with $83. Morning is the most expensive time of the day with prices starting from $103.

How to save money travelling from Charlotte to St. Louis, MO

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Charlotte to St. Louis, MO in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Charlotte to St. Louis, MO, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Charlotte to St. Louis, MO are also emptier.

Beloved bus companies from Charlotte to St. Louis, MO

These are the most booked bus companies between Charlotte to St. Louis, MO from our users.

FlixBus from Charlotte to St. Louis, MO

Here you will find the key facts about the FlixBus bus route Charlotte to St. Louis, MO:

Cheapest Price	$103
Fastest Bus	15h 30m
Earliest Bus	12:55 AM
Last Bus	11:40 PM
Daily Connections	7 Ø
Found on	11/30/2025

Greyhound US from Charlotte to St. Louis, MO

Here you will find the key facts about the Greyhound US bus route Charlotte to St. Louis, MO:

Cheapest Price	$103
Fastest Bus	17h 25m
Earliest Bus	2:50 AM
Last Bus	10:30 PM
Daily Connections	6 Ø
Found on	11/30/2025

All bus stations and stops in Charlotte and St. Louis, MO

In the map below, you can see where to find all bus stations in Charlotte and St. Louis, MO.

W Trade St

W Trade St 601

Freedom Drive 3301

Freedom Dr 3301

Central Bus Station

Church St

S Church St 330

Arrowood Light Rail Station

South Blvd 7430

Gateway Station

S 15th St 430

Skinker Boulevard

Boulevard between Lindell Blvd. and Lagoon Drive

Lindbergh @ Hackberry NB Bus Stop

Service and Comfort on the bus from Charlotte to St. Louis, MO

Want to know which seat classes are available on the buses from Charlotte to St. Louis, MO? Or which bus companies serve the route Charlotte to St. Louis, MO? Below you will find answers to your questions.

FAQs about the Charlotte to St. Louis, MO bus

How much does a Charlotte St. Louis, MO bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $83 and takes 21h 35m to reach St. Louis, MO. Compare offers to save money!

How much could I save by comparing buses from Charlotte to St. Louis, MO?

This route is offered by 2 companies with a range of ticket prices between $83 and $152. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to St. Louis, MO.

On average, how many connections are available from Charlotte to St. Louis, MO each day?

Every day, the Charlotte to St. Louis, MO bus route is served by approximately 13 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Charlotte to St. Louis, MO take?

The fastest bus from Charlotte to St. Louis, MO is offered by FlixBus and takes 15h 30m. Bus tickets for this connection cost $124. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Charlotte to St. Louis, MO?

The earliest bus arriving in St. Louis, MO from Charlotte starts at 12:55 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Charlotte to St. Louis, MO?

The latest bus trip departing from Charlotte for St. Louis, MO starts at 11:40 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Charlotte St. Louis, MO route?

When traveling by bus from Charlotte to St. Louis, MO, passengers can travel with FlixBus and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Charlotte and St. Louis, MO?

You can check all the direct connections between Charlotte and St. Louis, MO by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound US.

What can I take with me on the Charlotte to St. Louis, MO bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Charlotte St. Louis, MO bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Charlotte St. Louis, MO bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Charlotte to St. Louis, MO on your planned travel date.

Available seat classes which are offered on the bus route Charlotte to St. Louis, MO

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Charlotte and to St. Louis, MO

Here’s an overview of the most popular bus routes to Charlotte and to St. Louis, MO. Simply click on the connection of your choice, and you will find all the details about your bus route!