Bus Charlotte to St. Louis, MO - Compare all Companies

Compare all timetables for the bus from Charlotte to St. Louis, MO

Here is a selection of the cheapest bus trips from the schedule from Charlotte to St. Louis, MO from various bus operators like FlixBus or Greyhound US for the next days.

today

$157

tomorrow

Tuesday

Wednesday

$119

Thursday

$115

Friday

$113

Saturday

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	18h 45m	10:10 PM	Charlotte	W Trade St	3:55 PM	St. Louis, MO	Gateway Station	Economy	$157	A Bus from Greyhound US goes from W Trade St, Charlotte (USA) at 3/22/2026 10:10:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 3/23/2026 3:55:00 PM. 50 Economy ticket for $157 per person are available. Travel duration is 18h 45m
Greyhound US	22h 25m	6:20 PM	Charlotte	W Trade St	3:45 PM	St. Louis, MO	Gateway Station	Economy	$158	A Bus from Greyhound US goes from W Trade St, Charlotte (USA) at 3/22/2026 6:20:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 3/23/2026 3:45:00 PM. 50 Economy ticket for $158 per person are available. Travel duration is 22h 25m
FlixBus	33h 15m	6:55 AM	Charlotte	Freedom Drive 3301	3:10 PM	St. Louis, MO	Gateway Station	Economy	$178	A Bus from FlixBus goes from Freedom Drive 3301, Charlotte (USA) at 3/22/2026 6:55:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 3/23/2026 3:10:00 PM. 50 Economy ticket for $178 per person are available. Travel duration is 33h 15m
Greyhound US	27h 20m	12:50 PM	Charlotte	W Trade St	3:10 PM	St. Louis, MO	Gateway Station	Economy	$188	A Bus from Greyhound US goes from W Trade St, Charlotte (USA) at 3/22/2026 12:50:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 3/23/2026 3:10:00 PM. 50 Economy ticket for $188 per person are available. Travel duration is 27h 20m
FlixBus	33h 15m	11:40 PM	Charlotte	Freedom Drive 3301	7:55 AM	St. Louis, MO	Gateway Station	Economy	$189	A Bus from FlixBus goes from Freedom Drive 3301, Charlotte (USA) at 3/22/2026 11:40:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 3/24/2026 7:55:00 AM. 50 Economy ticket for $189 per person are available. Travel duration is 33h 15m

Did you know that if you travel from Charlotte to St. Louis, MO via Nashville, you can save more than $38? You can find the corresponding connections below.
- FlixBus
  
  16h 35m
  
  0
  
  5:35 PM
  
  Charlotte
  W Trade St
  
  2:50 AM
  
  Nashville
  5th Ave South Station
  
  0
  
  Economy
  
  $85
  
  A Bus from FlixBus goes from W Trade St, Charlotte (USA) at 3/24/2026 5:35:00 PM to 5th Ave South Station, Nashville (USA) arriving at 3/25/2026 2:50:00 AM. 50 Economy ticket for $85 per person are available. Travel duration is 10h 15m
- FlixBus
  
  6h 5m
  
  0
  
  3:05 AM
  
  Nashville
  5th Ave South Station
  
  9:10 AM
  
  St. Louis, MO
  Gateway Station
  
  0
  
  Economy
  
  $34
  
  A Bus from FlixBus goes from 5th Ave South Station, Nashville (USA) at 3/25/2026 3:05:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 3/25/2026 9:10:00 AM. 50 Economy ticket for $34 per person are available. Travel duration is 6h 5m
Travel Time is 1h 10m shorter, and you will save $38

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	20h 55m	1:15 PM	Charlotte	W Trade St	9:10 AM	St. Louis, MO	Gateway Station	Economy	$119	A Bus from FlixBus goes from W Trade St, Charlotte (USA) at 3/25/2026 1:15:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 3/26/2026 9:10:00 AM. 50 Economy ticket for $119 per person are available. Travel duration is 20h 55m
Greyhound US	18h 45m	10:10 PM	Charlotte	W Trade St	3:55 PM	St. Louis, MO	Gateway Station	Economy	$120	A Bus from Greyhound US goes from W Trade St, Charlotte (USA) at 3/25/2026 10:10:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 3/26/2026 3:55:00 PM. 50 Economy ticket for $120 per person are available. Travel duration is 18h 45m
FlixBus	33h 15m	6:55 AM	Charlotte	Freedom Drive 3301	3:10 PM	St. Louis, MO	Gateway Station	Economy	$121	A Bus from FlixBus goes from Freedom Drive 3301, Charlotte (USA) at 3/25/2026 6:55:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 3/26/2026 3:10:00 PM. 50 Economy ticket for $121 per person are available. Travel duration is 33h 15m
FlixBus	33h 15m	11:40 PM	Charlotte	Freedom Drive 3301	7:55 AM	St. Louis, MO	Gateway Station	Economy	$121	A Bus from FlixBus goes from Freedom Drive 3301, Charlotte (USA) at 3/25/2026 11:40:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 3/27/2026 7:55:00 AM. 50 Economy ticket for $121 per person are available. Travel duration is 33h 15m
Greyhound US	27h 20m	12:50 PM	Charlotte	W Trade St	3:10 PM	St. Louis, MO	Gateway Station	Economy	$121	A Bus from Greyhound US goes from W Trade St, Charlotte (USA) at 3/25/2026 12:50:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 3/26/2026 3:10:00 PM. 50 Economy ticket for $121 per person are available. Travel duration is 27h 20m

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	23h 5m	12:55 AM	Charlotte	W Trade St	11:00 PM	St. Louis, MO	Gateway Station	Economy	$115	A Bus from FlixBus goes from W Trade St, Charlotte (USA) at 3/26/2026 12:55:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 3/26/2026 11:00:00 PM. 50 Economy ticket for $115 per person are available. Travel duration is 23h 5m
FlixBus	30h 15m	6:05 PM	Charlotte	Freedom Drive 3301	11:20 PM	St. Louis, MO	Gateway Station	Economy	$115	A Bus from FlixBus goes from Freedom Drive 3301, Charlotte (USA) at 3/26/2026 6:05:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 3/27/2026 11:20:00 PM. 50 Economy ticket for $115 per person are available. Travel duration is 30h 15m
Greyhound US	21h 30m	2:50 AM	Charlotte	W Trade St	11:20 PM	St. Louis, MO	Gateway Station	Economy	$115	A Bus from Greyhound US goes from W Trade St, Charlotte (USA) at 3/26/2026 2:50:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 3/26/2026 11:20:00 PM. 50 Economy ticket for $115 per person are available. Travel duration is 21h 30m
FlixBus	27h 40m	6:55 AM	Charlotte	Freedom Drive 3301	9:35 AM	St. Louis, MO	Gateway Station	Economy	$116	A Bus from FlixBus goes from Freedom Drive 3301, Charlotte (USA) at 3/26/2026 6:55:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 3/27/2026 9:35:00 AM. 50 Economy ticket for $116 per person are available. Travel duration is 27h 40m
Greyhound US	16h 15m	6:20 PM	Charlotte	W Trade St	9:35 AM	St. Louis, MO	Gateway Station	Economy	$116	A Bus from Greyhound US goes from W Trade St, Charlotte (USA) at 3/26/2026 6:20:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 3/27/2026 9:35:00 AM. 50 Economy ticket for $116 per person are available. Travel duration is 16h 15m

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	23h 5m	12:55 AM	Charlotte	W Trade St	11:00 PM	St. Louis, MO	Gateway Station	Economy	$113	A Bus from FlixBus goes from W Trade St, Charlotte (USA) at 3/27/2026 12:55:00 AM to Gateway Station, St. Louis, MO (USA) arriving at 3/27/2026 11:00:00 PM. 50 Economy ticket for $113 per person are available. Travel duration is 23h 5m
FlixBus	30h 20m	6:05 PM	Charlotte	Freedom Drive 3301	11:25 PM	St. Louis, MO	Gateway Station	Economy	$113	A Bus from FlixBus goes from Freedom Drive 3301, Charlotte (USA) at 3/27/2026 6:05:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 3/28/2026 11:25:00 PM. 50 Economy ticket for $113 per person are available. Travel duration is 30h 20m
FlixBus	16h 35m	5:35 PM	Charlotte	W Trade St	9:10 AM	St. Louis, MO	Gateway Station	Economy	$114	A Bus from FlixBus goes from W Trade St, Charlotte (USA) at 3/27/2026 5:35:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 3/28/2026 9:10:00 AM. 50 Economy ticket for $114 per person are available. Travel duration is 16h 35m
Greyhound US	22h 25m	6:20 PM	Charlotte	W Trade St	3:45 PM	St. Louis, MO	Gateway Station	Economy	$114	A Bus from Greyhound US goes from W Trade St, Charlotte (USA) at 3/27/2026 6:20:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 3/28/2026 3:45:00 PM. 50 Economy ticket for $114 per person are available. Travel duration is 22h 25m
Greyhound US	18h 45m	10:10 PM	Charlotte	W Trade St	3:55 PM	St. Louis, MO	Gateway Station	Economy	$114	A Bus from Greyhound US goes from W Trade St, Charlotte (USA) at 3/27/2026 10:10:00 PM to Gateway Station, St. Louis, MO (USA) arriving at 3/28/2026 3:55:00 PM. 50 Economy ticket for $114 per person are available. Travel duration is 18h 45m

Best Price Offer: The price for the cheapest bus from Charlotte to St. Louis, MO is $88 on 4/9/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Charlotte and St. Louis, MO

See here how frequent the connections between Charlotte and St. Louis, MO are, during different times and days of the week.

Wednesday is the busiest day, with more than 13 daily buses from Charlotte to St. Louis, MO. Friday has instead the fewest connections, with only 7 daily coaches between Charlotte and St. Louis, MO.

The busiest time of the day is the Evening, with 23 buses from Charlotte to St. Louis, MO, while Afternoon sees the fewest connections between Charlotte and St. Louis, MO, with 5 offers.

Facts about the bus from Charlotte to St. Louis, MO

Compare all providers like FlixBus and Greyhound US that travel 11 times every day by bus from Charlotte to St. Louis, MO in one click! Book your bus ticket from Charlotte to St. Louis, MO starting from $88!

Cheapest Bus	$88
Fastest Bus	15h 15m
Earliest Bus	6:55 AM
Latest Bus	10:10 PM
Daily Bus Routes	11 Ø
Distance	567.1 miles
Bus Companies	FlixBus and Greyhound US

Cheapest bus connections from Charlotte to St. Louis, MO

Every day, 11 buses from 2 bus companies leave Charlotte for St. Louis, MO: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 03/22/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 03/22

$158

Monday 03/23

Tuesday 03/24

Wednesday 03/25

$119

Thursday 03/26

$115

Friday 03/27

$113

Saturday 03/28

Sunday 03/29

$107

Monday 03/30

$112

Tuesday 03/31

Wednesday 04/01

$127

Thursday 04/02

Friday 04/03

Saturday 04/04

$107

Sunday 04/05

$100

Monday 04/06

$94

Tuesday 04/07

$110

Wednesday 04/08

Thursday 04/09

$88

Friday 04/10

$101

Saturday 04/11

$109

Sunday 04/12

$105

Monday 04/13

$94

Tuesday 04/14

$102

Wednesday 04/15

$116

Thursday 04/16

Friday 04/17

$101

Saturday 04/18

The cheapest time to travel from Charlotte to St. Louis, MO

See here on which day and which time of the day you can find the cheapest bus ticket from Charlotte to St. Louis, MO, for the next 30 days.

With a price starting from $88, Thursday is the cheapest day for a bus from Charlotte to St. Louis, MO. Wednesday instead is the most expensive day with prices starting from $116.

Night is the cheapest day time for bus tickets from Charlotte to St. Louis, MO, with $88. Morning is the most expensive time of the day with prices starting from $115.

How to save money travelling from Charlotte to St. Louis, MO

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Charlotte to St. Louis, MO in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Charlotte to St. Louis, MO, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Charlotte to St. Louis, MO are also emptier.

Beloved bus companies from Charlotte to St. Louis, MO

These are the most booked bus companies between Charlotte to St. Louis, MO from our users.

FlixBus from Charlotte to St. Louis, MO

Here you will find the key facts about the FlixBus bus route Charlotte to St. Louis, MO:

Cheapest Price	$113
Fastest Bus	15h 35m
Earliest Bus	6:55 AM
Last Bus	6:05 PM
Daily Connections	6 Ø
Found on	3/17/2026

All bus stations and stops in Charlotte and St. Louis, MO

In the map below, you can see where to find all bus stations in Charlotte and St. Louis, MO.

W Trade St

W Trade St 601

Freedom Drive 3301

Freedom Dr 3301

Central Bus Station

Arrowood Light Rail Station

South Blvd 7430

Church St

S Church St 330

Gateway Station

S 15th St 430

Skinker Boulevard

Boulevard between Lindell Blvd. and Lagoon Drive

Lindbergh @ Hackberry NB Bus Stop

Service and Comfort on the bus from Charlotte to St. Louis, MO

Want to know which seat classes are available on the buses from Charlotte to St. Louis, MO? Or which bus companies serve the route Charlotte to St. Louis, MO? Below you will find answers to your questions.

FAQs about the Charlotte to St. Louis, MO bus

How much does a Charlotte St. Louis, MO bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $88 and takes 22h 5m to reach St. Louis, MO. Compare offers to save money!

How much could I save by comparing buses from Charlotte to St. Louis, MO?

This route is offered by 2 companies with a range of ticket prices between $88 and $193. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to St. Louis, MO.

On average, how many connections are available from Charlotte to St. Louis, MO each day?

Every day, the Charlotte to St. Louis, MO bus route is served by approximately 11 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Charlotte to St. Louis, MO take?

The fastest bus from Charlotte to St. Louis, MO is offered by Greyhound US and takes 15h 15m. Bus tickets for this connection cost $116. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Charlotte to St. Louis, MO?

The earliest bus arriving in St. Louis, MO from Charlotte starts at 6:55 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Charlotte to St. Louis, MO?

The latest bus trip departing from Charlotte for St. Louis, MO starts at 10:10 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Charlotte St. Louis, MO route?

When traveling by bus from Charlotte to St. Louis, MO, passengers can travel with FlixBus and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Charlotte and St. Louis, MO?

You can check all the direct connections between Charlotte and St. Louis, MO by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound US.

What can I take with me on the Charlotte to St. Louis, MO bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Charlotte St. Louis, MO bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Charlotte St. Louis, MO bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Charlotte to St. Louis, MO on your planned travel date.

How does CheckMyBus find the best bus deals from Charlotte to St. Louis, MO?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 11 daily trips between Charlotte and St. Louis, MO. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Charlotte to St. Louis, MO?

Prices and availability for 11 trips between Charlotte and St. Louis, MO change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Charlotte to St. Louis, MO

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Charlotte and to St. Louis, MO

Here’s an overview of the most popular bus routes to Charlotte and to St. Louis, MO. Simply click on the connection of your choice, and you will find all the details about your bus route!