Bus Buffalo, NY to Charlotte - Compare all Companies

Compare all timetables for the bus from Buffalo, NY to Charlotte

Here is a selection of the cheapest bus trips from the schedule from Buffalo, NY to Charlotte from various bus operators like FlixBus or Greyhound US for the next days.

today

$88

tomorrow

$99

Wednesday

$100

Thursday

$102

Friday

$109

Saturday

$89

Sunday

$86

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	23h 30m	5:30 AM	Buffalo, NY	Central Bus Station	5:00 AM	Charlotte	W Trade St	Economy	$88	A Bus from FlixBus goes from Central Bus Station, Buffalo, NY (USA) at 6/22/2026 5:30:00 AM to W Trade St, Charlotte (USA) arriving at 6/23/2026 5:00:00 AM. 50 Economy ticket for $88 per person are available. Travel duration is 23h 30m
FlixBus	23h 0m	7:30 AM	Buffalo, NY	Central Bus Station	6:30 AM	Charlotte	W Trade St	Economy	$89	A Bus from FlixBus goes from Central Bus Station, Buffalo, NY (USA) at 6/22/2026 7:30:00 AM to W Trade St, Charlotte (USA) arriving at 6/23/2026 6:30:00 AM. 50 Economy ticket for $89 per person are available. Travel duration is 23h 0m
FlixBus	23h 0m	10:30 AM	Buffalo, NY	Central Bus Station	9:30 AM	Charlotte	W Trade St	Economy	$89	A Bus from FlixBus goes from Central Bus Station, Buffalo, NY (USA) at 6/22/2026 10:30:00 AM to W Trade St, Charlotte (USA) arriving at 6/23/2026 9:30:00 AM. 50 Economy ticket for $89 per person are available. Travel duration is 23h 0m
Greyhound US	24h 5m	5:20 PM	Buffalo, NY	Central Bus Station	5:25 PM	Charlotte	W Trade St	Economy	$89	A Bus from Greyhound US goes from Central Bus Station, Buffalo, NY (USA) at 6/22/2026 5:20:00 PM to W Trade St, Charlotte (USA) arriving at 6/23/2026 5:25:00 PM. 50 Economy ticket for $89 per person are available. Travel duration is 24h 5m

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	24h 46m	11:59 PM	Buffalo, NY	Central Bus Station	12:45 AM	Charlotte	W Trade St	Economy	$99	A Bus from FlixBus goes from Central Bus Station, Buffalo, NY (USA) at 6/23/2026 11:59:00 PM to W Trade St, Charlotte (USA) arriving at 6/25/2026 12:45:00 AM. 50 Economy ticket for $99 per person are available. Travel duration is 24h 46m
FlixBus	23h 30m	5:30 AM	Buffalo, NY	Central Bus Station	5:00 AM	Charlotte	W Trade St	Economy	$100	A Bus from FlixBus goes from Central Bus Station, Buffalo, NY (USA) at 6/23/2026 5:30:00 AM to W Trade St, Charlotte (USA) arriving at 6/24/2026 5:00:00 AM. 50 Economy ticket for $100 per person are available. Travel duration is 23h 30m
FlixBus	30h 51m	11:59 PM	Buffalo, NY	Central Bus Station	6:50 AM	Charlotte	Freedom Drive 3301	Economy	$100	A Bus from FlixBus goes from Central Bus Station, Buffalo, NY (USA) at 6/23/2026 11:59:00 PM to Freedom Drive 3301, Charlotte (USA) arriving at 6/25/2026 6:50:00 AM. 50 Economy ticket for $100 per person are available. Travel duration is 30h 51m
Greyhound US	28h 0m	3:40 PM	Buffalo, NY	Central Bus Station	7:40 PM	Charlotte	W Trade St	Economy	$104	A Bus from Greyhound US goes from Central Bus Station, Buffalo, NY (USA) at 6/23/2026 3:40:00 PM to W Trade St, Charlotte (USA) arriving at 6/24/2026 7:40:00 PM. 50 Economy ticket for $104 per person are available. Travel duration is 28h 0m

Cheapest bus trips Wednesday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	30h 51m	11:59 PM	Buffalo, NY	Central Bus Station	6:50 AM	Charlotte	Freedom Drive 3301	Economy	$100	A Bus from FlixBus goes from Central Bus Station, Buffalo, NY (USA) at 6/24/2026 11:59:00 PM to Freedom Drive 3301, Charlotte (USA) arriving at 6/26/2026 6:50:00 AM. 50 Economy ticket for $100 per person are available. Travel duration is 30h 51m
FlixBus	23h 0m	7:30 AM	Buffalo, NY	Central Bus Station	6:30 AM	Charlotte	W Trade St	Economy	$101	A Bus from FlixBus goes from Central Bus Station, Buffalo, NY (USA) at 6/24/2026 7:30:00 AM to W Trade St, Charlotte (USA) arriving at 6/25/2026 6:30:00 AM. 50 Economy ticket for $101 per person are available. Travel duration is 23h 0m
FlixBus	24h 46m	11:59 PM	Buffalo, NY	Central Bus Station	12:45 AM	Charlotte	W Trade St	Economy	$101	A Bus from FlixBus goes from Central Bus Station, Buffalo, NY (USA) at 6/24/2026 11:59:00 PM to W Trade St, Charlotte (USA) arriving at 6/26/2026 12:45:00 AM. 50 Economy ticket for $101 per person are available. Travel duration is 24h 46m
Greyhound US	28h 0m	3:40 PM	Buffalo, NY	Central Bus Station	7:40 PM	Charlotte	W Trade St	Economy	$101	A Bus from Greyhound US goes from Central Bus Station, Buffalo, NY (USA) at 6/24/2026 3:40:00 PM to W Trade St, Charlotte (USA) arriving at 6/25/2026 7:40:00 PM. 50 Economy ticket for $101 per person are available. Travel duration is 28h 0m

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	23h 0m	7:30 AM	Buffalo, NY	Central Bus Station	6:30 AM	Charlotte	W Trade St	Economy	$102	A Bus from FlixBus goes from Central Bus Station, Buffalo, NY (USA) at 6/25/2026 7:30:00 AM to W Trade St, Charlotte (USA) arriving at 6/26/2026 6:30:00 AM. 50 Economy ticket for $102 per person are available. Travel duration is 23h 0m
FlixBus	23h 20m	7:30 AM	Buffalo, NY	Central Bus Station	6:50 AM	Charlotte	Freedom Drive 3301	Economy	$102	A Bus from FlixBus goes from Central Bus Station, Buffalo, NY (USA) at 6/25/2026 7:30:00 AM to Freedom Drive 3301, Charlotte (USA) arriving at 6/26/2026 6:50:00 AM. 50 Economy ticket for $102 per person are available. Travel duration is 23h 20m
FlixBus	30h 51m	11:59 PM	Buffalo, NY	Central Bus Station	6:50 AM	Charlotte	Freedom Drive 3301	Economy	$102	A Bus from FlixBus goes from Central Bus Station, Buffalo, NY (USA) at 6/25/2026 11:59:00 PM to Freedom Drive 3301, Charlotte (USA) arriving at 6/27/2026 6:50:00 AM. 50 Economy ticket for $102 per person are available. Travel duration is 30h 51m
Greyhound US	24h 5m	5:20 PM	Buffalo, NY	Central Bus Station	5:25 PM	Charlotte	W Trade St	Economy	$115	A Bus from Greyhound US goes from Central Bus Station, Buffalo, NY (USA) at 6/25/2026 5:20:00 PM to W Trade St, Charlotte (USA) arriving at 6/26/2026 5:25:00 PM. 50 Economy ticket for $115 per person are available. Travel duration is 24h 5m

Did you know that if you travel from Buffalo, NY to Charlotte via Niagara Falls, NY, you can save more than $12? You can find the corresponding connections below.
- FlixBus
  
  27h 55m
  
  0
  
  1:05 AM
  
  Buffalo, NY
  Central Bus Station
  
  1:30 AM
  
  Niagara Falls, NY
  Charter bus zone behind visitor center
  
  0
  
  Economy
  
  $5
  
  A Bus from FlixBus goes from Central Bus Station, Buffalo, NY (USA) at 6/27/2026 1:05:00 AM to Charter bus zone behind visitor center, Niagara Falls, NY (USA) arriving at 6/27/2026 1:30:00 AM. 50 Economy ticket for $5 per person are available. Travel duration is 0h 25m
- FlixBus
  
  24h 10m
  
  0
  
  4:50 AM
  
  Niagara Falls, NY
  Charter bus zone behind visitor center
  
  5:00 AM
  
  Charlotte
  W Trade St
  
  0
  
  Economy
  
  $85
  
  A Bus from FlixBus goes from Charter bus zone behind visitor center, Niagara Falls, NY (USA) at 6/27/2026 4:50:00 AM to W Trade St, Charlotte (USA) arriving at 6/28/2026 5:00:00 AM. 50 Economy ticket for $85 per person are available. Travel duration is 24h 10m
Travel time is 4h 55m longer, but you will save $12

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	23h 0m	7:30 AM	Buffalo, NY	Central Bus Station	6:30 AM	Charlotte	W Trade St	Economy	$109	A Bus from FlixBus goes from Central Bus Station, Buffalo, NY (USA) at 6/26/2026 7:30:00 AM to W Trade St, Charlotte (USA) arriving at 6/27/2026 6:30:00 AM. 50 Economy ticket for $109 per person are available. Travel duration is 23h 0m
FlixBus	23h 20m	7:30 AM	Buffalo, NY	Central Bus Station	6:50 AM	Charlotte	Freedom Drive 3301	Economy	$109	A Bus from FlixBus goes from Central Bus Station, Buffalo, NY (USA) at 6/26/2026 7:30:00 AM to Freedom Drive 3301, Charlotte (USA) arriving at 6/27/2026 6:50:00 AM. 50 Economy ticket for $109 per person are available. Travel duration is 23h 20m
FlixBus	24h 46m	11:59 PM	Buffalo, NY	Central Bus Station	12:45 AM	Charlotte	W Trade St	Economy	$110	A Bus from FlixBus goes from Central Bus Station, Buffalo, NY (USA) at 6/26/2026 11:59:00 PM to W Trade St, Charlotte (USA) arriving at 6/28/2026 12:45:00 AM. 50 Economy ticket for $110 per person are available. Travel duration is 24h 46m
Greyhound US	24h 5m	5:20 PM	Buffalo, NY	Central Bus Station	5:25 PM	Charlotte	W Trade St	Economy	$123	A Bus from Greyhound US goes from Central Bus Station, Buffalo, NY (USA) at 6/26/2026 5:20:00 PM to W Trade St, Charlotte (USA) arriving at 6/27/2026 5:25:00 PM. 50 Economy ticket for $123 per person are available. Travel duration is 24h 5m

Did you know that if you travel from Buffalo, NY to Charlotte via Niagara Falls, NY, you can save more than $26? You can find the corresponding connections below.
- FlixBus
  
  31h 35m
  
  0
  
  10:55 PM
  
  Buffalo, NY
  Central Bus Station
  
  11:25 PM
  
  Niagara Falls, NY
  Charter bus zone behind visitor center
  
  0
  
  Economy
  
  $5
  
  A Bus from FlixBus goes from Central Bus Station, Buffalo, NY (USA) at 6/27/2026 10:55:00 PM to Charter bus zone behind visitor center, Niagara Falls, NY (USA) arriving at 6/27/2026 11:25:00 PM. 50 Economy ticket for $5 per person are available. Travel duration is 0h 30m
- FlixBus
  
  23h 40m
  
  0
  
  6:50 AM
  
  Niagara Falls, NY
  Charter bus zone behind visitor center
  
  6:30 AM
  
  Charlotte
  W Trade St
  
  0
  
  Economy
  
  $78
  
  A Bus from FlixBus goes from Charter bus zone behind visitor center, Niagara Falls, NY (USA) at 6/28/2026 6:50:00 AM to W Trade St, Charlotte (USA) arriving at 6/29/2026 6:30:00 AM. 50 Economy ticket for $78 per person are available. Travel duration is 23h 40m
Travel time is 8h 35m longer, but you will save $26

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	23h 0m	10:30 AM	Buffalo, NY	Central Bus Station	9:30 AM	Charlotte	W Trade St	Economy	$89	A Bus from FlixBus goes from Central Bus Station, Buffalo, NY (USA) at 6/27/2026 10:30:00 AM to W Trade St, Charlotte (USA) arriving at 6/28/2026 9:30:00 AM. 50 Economy ticket for $89 per person are available. Travel duration is 23h 0m
FlixBus	30h 51m	11:59 PM	Buffalo, NY	Central Bus Station	6:50 AM	Charlotte	Freedom Drive 3301	Economy	$89	A Bus from FlixBus goes from Central Bus Station, Buffalo, NY (USA) at 6/27/2026 11:59:00 PM to Freedom Drive 3301, Charlotte (USA) arriving at 6/29/2026 6:50:00 AM. 50 Economy ticket for $89 per person are available. Travel duration is 30h 51m
FlixBus	23h 30m	5:30 AM	Buffalo, NY	Central Bus Station	5:00 AM	Charlotte	W Trade St	Economy	$90	A Bus from FlixBus goes from Central Bus Station, Buffalo, NY (USA) at 6/27/2026 5:30:00 AM to W Trade St, Charlotte (USA) arriving at 6/28/2026 5:00:00 AM. 50 Economy ticket for $90 per person are available. Travel duration is 23h 30m
Greyhound US	24h 5m	5:20 PM	Buffalo, NY	Central Bus Station	5:25 PM	Charlotte	W Trade St	Economy	$100	A Bus from Greyhound US goes from Central Bus Station, Buffalo, NY (USA) at 6/27/2026 5:20:00 PM to W Trade St, Charlotte (USA) arriving at 6/28/2026 5:25:00 PM. 50 Economy ticket for $100 per person are available. Travel duration is 24h 5m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
FlixBus	23h 0m	7:30 AM	Buffalo, NY	Central Bus Station	6:30 AM	Charlotte	W Trade St	Economy	$86	A Bus from FlixBus goes from Central Bus Station, Buffalo, NY (USA) at 6/28/2026 7:30:00 AM to W Trade St, Charlotte (USA) arriving at 6/29/2026 6:30:00 AM. 50 Economy ticket for $86 per person are available. Travel duration is 23h 0m
FlixBus	23h 20m	7:30 AM	Buffalo, NY	Central Bus Station	6:50 AM	Charlotte	Freedom Drive 3301	Economy	$86	A Bus from FlixBus goes from Central Bus Station, Buffalo, NY (USA) at 6/28/2026 7:30:00 AM to Freedom Drive 3301, Charlotte (USA) arriving at 6/29/2026 6:50:00 AM. 50 Economy ticket for $86 per person are available. Travel duration is 23h 20m
FlixBus	24h 46m	11:59 PM	Buffalo, NY	Central Bus Station	12:45 AM	Charlotte	W Trade St	Economy	$87	A Bus from FlixBus goes from Central Bus Station, Buffalo, NY (USA) at 6/28/2026 11:59:00 PM to W Trade St, Charlotte (USA) arriving at 6/30/2026 12:45:00 AM. 50 Economy ticket for $87 per person are available. Travel duration is 24h 46m
Greyhound US	24h 5m	5:20 PM	Buffalo, NY	Central Bus Station	5:25 PM	Charlotte	W Trade St	Economy	$96	A Bus from Greyhound US goes from Central Bus Station, Buffalo, NY (USA) at 6/28/2026 5:20:00 PM to W Trade St, Charlotte (USA) arriving at 6/29/2026 5:25:00 PM. 50 Economy ticket for $96 per person are available. Travel duration is 24h 5m

Best Price Offer: The price for the cheapest bus from Buffalo, NY to Charlotte is $86 on 6/28/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Buffalo, NY and Charlotte

See here how frequent the connections between Buffalo, NY and Charlotte are, during different times and days of the week.

Sunday is the busiest day, with more than 16 daily buses from Buffalo, NY to Charlotte. Tuesday has instead the fewest connections, with only 8 daily coaches between Buffalo, NY and Charlotte.

The busiest time of the day is the Morning, with 39 buses from Buffalo, NY to Charlotte, while Afternoon sees the fewest connections between Buffalo, NY and Charlotte, with 13 offers.

Facts about the bus from Buffalo, NY to Charlotte

Compare all providers like FlixBus and Greyhound US that travel 14 times every day by bus from Buffalo, NY to Charlotte in one click! Book your bus ticket from Buffalo, NY to Charlotte starting from $86!

Cheapest Bus	$86
Fastest Bus	22h 35m
Earliest Bus	3:30 AM
Latest Bus	11:59 PM
Daily Bus Routes	14 Ø
Distance	542.3 miles
Bus Companies	FlixBus and Greyhound US

Cheapest bus connections from Buffalo, NY to Charlotte

Every day, 14 buses from 2 bus companies leave Buffalo, NY for Charlotte: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 06/22/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 06/21

Monday 06/22

$101

Tuesday 06/23

$99

Wednesday 06/24

$100

Thursday 06/25

$106

Friday 06/26

$113

Saturday 06/27

$104

Sunday 06/28

$86

Monday 06/29

Tuesday 06/30

Wednesday 07/01

Thursday 07/02

Friday 07/03

Saturday 07/04

$100

Sunday 07/05

$95

Monday 07/06

Tuesday 07/07

Wednesday 07/08

Thursday 07/09

$109

Friday 07/10

Saturday 07/11

$97

Sunday 07/12

$92

Monday 07/13

Tuesday 07/14

$112

Wednesday 07/15

$93

Thursday 07/16

$95

Friday 07/17

$97

Saturday 07/18

The cheapest time to travel from Buffalo, NY to Charlotte

See here on which day and which time of the day you can find the cheapest bus ticket from Buffalo, NY to Charlotte, for the next 30 days.

With a price starting from $86, Sunday is the cheapest day for a bus from Buffalo, NY to Charlotte. Tuesday instead is the most expensive day with prices starting from $99.

Morning is the cheapest day time for bus tickets from Buffalo, NY to Charlotte, with $86. Afternoon is the most expensive time of the day with prices starting from $89.

How to save money travelling from Buffalo, NY to Charlotte

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Buffalo, NY to Charlotte in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Buffalo, NY to Charlotte, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Buffalo, NY to Charlotte are also emptier.

All bus stations and stops in Buffalo, NY and Charlotte

In the map below, you can see where to find all bus stations in Buffalo, NY and Charlotte.

Central Bus Station

Ellicott Street 181

MTC / Downtown Terminal

Ellicott Street 181

Maple Road Gulf

Maple Rd 4641

Asia Food Market

Niagara Falls Blvd 2055

Cleveland Hall

W Trade St

W Trade St 601

Freedom Drive 3301

Freedom Dr 3301

Central Bus Station

Arrowood Light Rail Station

South Blvd 7430

Church St

S Church St 330

Service and Comfort on the bus from Buffalo, NY to Charlotte

Want to know which seat classes are available on the buses from Buffalo, NY to Charlotte? Or which bus companies serve the route Buffalo, NY to Charlotte? Below you will find answers to your questions.

FAQs about the Buffalo, NY to Charlotte bus

How much does a Buffalo, NY Charlotte bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $86 and takes 23h 0m to reach Charlotte. Compare offers to save money!

How much could I save by comparing buses from Buffalo, NY to Charlotte?

This route is offered by 2 companies with a range of ticket prices between $86 and $158. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Charlotte.

On average, how many connections are available from Buffalo, NY to Charlotte each day?

Every day, the Buffalo, NY to Charlotte bus route is served by approximately 14 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Buffalo, NY to Charlotte take?

The fastest bus from Buffalo, NY to Charlotte is offered by FlixBus and takes 22h 35m. Bus tickets for this connection cost $101. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Buffalo, NY to Charlotte?

The earliest bus arriving in Charlotte from Buffalo, NY starts at 3:30 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Buffalo, NY to Charlotte?

The latest bus trip departing from Buffalo, NY for Charlotte starts at 11:59 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Buffalo, NY Charlotte route?

When traveling by bus from Buffalo, NY to Charlotte, passengers can travel with FlixBus and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Buffalo, NY and Charlotte?

You can check all the direct connections between Buffalo, NY and Charlotte by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound US.

What can I take with me on the Buffalo, NY to Charlotte bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Buffalo, NY Charlotte bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Buffalo, NY Charlotte bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Buffalo, NY to Charlotte on your planned travel date.

How does CheckMyBus find the best bus deals from Buffalo, NY to Charlotte?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 14 daily trips between Buffalo, NY and Charlotte. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Buffalo, NY to Charlotte?

Prices and availability for 14 trips between Buffalo, NY and Charlotte change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Buffalo, NY to Charlotte

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Buffalo, NY and to Charlotte

Here’s an overview of the most popular bus routes to Buffalo, NY and to Charlotte. Simply click on the connection of your choice, and you will find all the details about your bus route!