Compare all timetables for the bus from Florence, SC to Charlotte
Here is a selection of the cheapest bus trips from the schedule from Florence, SC to Charlotte from various bus operators like FlixBus or Greyhound US for the next days.
| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 5h 40m | 3:20 PM | Florence, SC | Bus Station | 9:00 PM | Charlotte | W Trade St | Economy | $39 |
A Bus from Greyhound US goes from Bus Station, Florence, SC (USA) at 11/3/2026 3:20:00 PM to W Trade St, Charlotte (USA) arriving at 11/3/2026 9:00:00 PM. 50 Economy ticket for $39 per person are available. Travel duration is 5h 40m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Greyhound US | 5h 40m | 3:20 PM | Florence, SC | Bus Station | 9:00 PM | Charlotte | W Trade St | Economy | $34 |
A Bus from Greyhound US goes from Bus Station, Florence, SC (USA) at 11/6/2026 3:20:00 PM to W Trade St, Charlotte (USA) arriving at 11/6/2026 9:00:00 PM. 50 Economy ticket for $34 per person are available. Travel duration is 5h 40m
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| FlixBus | 8h 15m | 12:05 AM | Florence, SC | TA Travel Center | 8:20 AM | Charlotte | W Trade St | Economy | $66 |
A Bus from FlixBus goes from TA Travel Center, Florence, SC (USA) at 11/6/2026 12:05:00 AM to W Trade St, Charlotte (USA) arriving at 11/6/2026 8:20:00 AM. 50 Economy ticket for $66 per person are available. Travel duration is 8h 15m
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| Mode of Transport | BertCompanyCountOneCompanyName | Duration | Departure time | From | Departure | Arrival time | To | Destination | Logo | Seat classes | Price | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FlixBus | 8h 15m | 12:05 AM | Florence, SC | TA Travel Center | 8:20 AM | Charlotte | W Trade St | Economy | $62 |
A Bus from FlixBus goes from TA Travel Center, Florence, SC (USA) at 11/9/2026 12:05:00 AM to W Trade St, Charlotte (USA) arriving at 11/9/2026 8:20:00 AM. 50 Economy ticket for $62 per person are available. Travel duration is 8h 15m
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Did you know that if you travel from Florence, SC to Charlotte via Myrtle Beach, SC, you can save more than $8? You can find the corresponding connections below.
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Greyhound US10h 50m010:10 AMFlorence, SCBus Station11:30 AMMyrtle Beach, SCBus Stop0EconomyA Bus from Greyhound US goes from Bus Station, Florence, SC (USA) at 11/5/2026 10:10:00 AM to Bus Stop, Myrtle Beach, SC (USA) arriving at 11/5/2026 11:30:00 AM. 50 Economy ticket for $15 per person are available. Travel duration is 1h 20m
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Greyhound US8h 15m012:45 PMMyrtle Beach, SCBus Stop9:00 PMCharlotteW Trade St0EconomyA Bus from Greyhound US goes from Bus Stop, Myrtle Beach, SC (USA) at 11/5/2026 12:45:00 PM to W Trade St, Charlotte (USA) arriving at 11/5/2026 9:00:00 PM. 50 Economy ticket for $38 per person are available. Travel duration is 8h 15m
Waiting Time 1h 15mTravel time is 2h 35m longer, but you will save $8 -
Best Price Offer: The price for the cheapest bus from Florence, SC to Charlotte is $34 on 11/6/2026. Flexible travelers save on ticket prices.
Frequency of bus connections between Florence, SC and Charlotte
Friday
is the busiest day, with more than 2 daily buses from Florence, SC to Charlotte. Monday has instead the fewest connections, with only 1 daily coaches between Florence, SC and Charlotte.
The busiest time of the day is the Afternoon, with 2 buses from Florence, SC to Charlotte, while Afternoon sees the fewest connections between Florence, SC and Charlotte, with 2 offers.
Facts about the bus from Florence, SC to Charlotte
Compare all providers like FlixBus and Greyhound US that travel 1 times every day by bus from Florence, SC to Charlotte in one click! Book your bus ticket from Florence, SC to Charlotte starting from $34!
| Cheapest Bus | $34 |
| Fastest Bus | 5h 40m |
| Earliest Bus | 3:20 PM |
| Latest Bus | 12:05 AM |
| Daily Bus Routes | 1 Ø |
| Distance | 93.5 miles |
| Bus Companies | FlixBus and Greyhound US |
Cheapest bus connections from Florence, SC to Charlotte
Every day, 1 buses from 2 bus companies leave Florence, SC for Charlotte: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 11/03/2026 and for the following days.
Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday
11/01
Monday
11/02
Tuesday
11/03
$39
Wednesday
11/04
Thursday
11/05
Friday
11/06
$66
Saturday
11/07
Sunday
11/08
Monday
11/09
$62
Tuesday
11/10
Wednesday
11/11
Thursday
11/12
$34
Friday
11/13
Saturday
11/14
$67
Sunday
11/15
Monday
11/16
Tuesday
11/17
$77
Wednesday
11/18
Thursday
11/19
$36
Friday
11/20
$37
Saturday
11/21
$37
Sunday
11/22
Monday
11/23
Tuesday
11/24
$48
Wednesday
11/25
Thursday
11/26
$46
Friday
11/27
Saturday
11/28
The cheapest time to travel from Florence, SC to Charlotte
With a price starting from $34, Friday is the cheapest day for a bus from Florence, SC to Charlotte. Monday instead is the most expensive day with prices starting from $62.
Afternoon
is the cheapest day time for bus tickets from Florence, SC to Charlotte, with $34. Night is the most expensive time of the day with prices starting from $34.
How to save money travelling from Florence, SC to Charlotte
Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:
Book the ticket from Florence, SC to Charlotte in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Florence, SC to Charlotte, compared instead if you buy it at the last moment, or directly at the station.
If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Florence, SC to Charlotte are also emptier.Beloved bus companies from Florence, SC to Charlotte
These are the most booked bus companies between Florence, SC to Charlotte from our users.
Greyhound US from Florence, SC to Charlotte
Here you will find the key facts about the Greyhound US bus route Florence, SC to Charlotte:
| Cheapest Price | $34 |
| Fastest Bus | 5h 40m |
| Earliest Bus | 3:20 PM |
| Last Bus | 3:20 PM |
| Daily Connections | 1 Ø |
| Found on | 10/6/2026 |
FlixBus from Florence, SC to Charlotte
Here you will find the key facts about the FlixBus bus route Florence, SC to Charlotte:
| Cheapest Price | $62 |
| Fastest Bus | 8h 15m |
| Earliest Bus | 12:05 AM |
| Last Bus | 12:05 AM |
| Daily Connections | 1 Ø |
| Found on | 10/10/2026 |
All bus stations and stops in Florence, SC and Charlotte
In the map below, you can see where to find all bus stations in Florence, SC and Charlotte.
Service and Comfort on the bus from Florence, SC to Charlotte
Want to know which seat classes are available on the buses from Florence, SC to Charlotte? Or which bus companies serve the route Florence, SC to Charlotte? Below you will find answers to your questions.
FAQs about the Florence, SC to Charlotte bus
How much does a Florence, SC Charlotte bus trip cost?
This depends on, among other things, the day and time of travel. The cheapest trip is available from $34 and takes 5h 40m to reach Charlotte. Compare offers to save money!
How much could I save by comparing buses from Florence, SC to Charlotte?
This route is offered by 2 companies with a range of ticket prices between $34 and $66. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Charlotte.
On average, how many connections are available from Florence, SC to Charlotte each day?
Every day, the Florence, SC to Charlotte bus route is served by approximately 1 connections. With our search, you can compare bus times to find the perfect trip.
How long does a bus journey from Florence, SC to Charlotte take?
The fastest bus from Florence, SC to Charlotte is offered by Greyhound US and takes 5h 40m. Bus tickets for this connection cost $39. In this context, bear in mind that the journey can take longer due to traffic.
What time is the first bus from Florence, SC to Charlotte?
The earliest bus arriving in Charlotte from Florence, SC starts at 3:20 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.
What time is the last bus from Florence, SC to Charlotte?
The latest bus trip departing from Florence, SC for Charlotte starts at 12:05 AM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.
Which bus companies operate the Florence, SC Charlotte route?
When traveling by bus from Florence, SC to Charlotte, passengers can travel with FlixBus and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.
Is there a direct bus between Florence, SC and Charlotte?
You can check all the direct connections between Florence, SC and Charlotte by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound US.
What can I take with me on the Florence, SC to Charlotte bus route?
Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Florence, SC Charlotte bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.
What equipment is available for the Florence, SC Charlotte bus route?
The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Florence, SC to Charlotte on your planned travel date.
How does CheckMyBus find the best bus deals from Florence, SC to Charlotte?
CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 1 daily trips between Florence, SC and Charlotte. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.
How does CheckMyBus technology work for trips from Florence, SC to Charlotte?
Prices and availability for 1 trips between Florence, SC and Charlotte change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.
Available seat classes which are offered on the bus route Florence, SC to Charlotte
Economy
The cheapest option available for your ticket, it usually comes with reclinable seats and AC.
More bus routes to Florence, SC and to Charlotte
Here’s an overview of the most popular bus routes to Florence, SC and to Charlotte. Simply click on the connection of your choice, and you will find all the details about your bus route!
- Bus Routes to Florence, SC
- Atlanta, GA to Florence, SC bus
- Bus Bangor, ME to Florence, SC
- Bus Cambridge, MA - Florence, SC
- Buses Charleston, SC to Florence, SC
- Buses to Florence, SC from Cherry Hill, NJ
- Buses to Florence, SC from Chicago
- From Columbia, SC to Florence, SC bus
- Buses Dallas to Florence, SC
- Bus to Florence, SC from Kansas City
- From Myrtle Beach, SC to Florence, SC bus
- Buses from New York to Florence, SC
- Newark to Florence, SC bus
- Bus Norfolk, VA - Florence, SC
- Bus Orlando, FL to Florence, SC
- Bus from Philadelphia to Florence, SC
- Bus Raleigh, NC to Florence, SC
- Bus from Richmond, VA to Florence, SC
- Buses Sumter, SC - Florence, SC
- Buses Syracuse, NY - Florence, SC
- Bus to Florence, SC from Washington, DC
- Bus Routes to Charlotte
- Bus Anderson, SC to Charlotte
- Bus from Asheville, NC to Charlotte
- Bus Atlanta, GA - Charlotte
- Bus Austin - Charlotte
- Buses to Charlotte from Boston, MA
- Buses Colonial Heights, VA - Charlotte
- Bus Columbia, SC - Charlotte
- Bus from Columbus, OH to Charlotte
- Buses Detroit to Charlotte
- Bus to Charlotte from McAlester, OK
- Bus Memphis - Charlotte
- Buses Myrtle Beach, SC - Charlotte
- From Nashville to Charlotte bus
- Buses New York to Charlotte
- Buses to Charlotte from Newark
- Raleigh, NC to Charlotte bus
- Saint Paul, MN to Charlotte bus
- Buses to Charlotte from Savannah, GA
- Buses from Washington, DC to Charlotte
- Winston-Salem, NC to Charlotte bus
Popular Airport Shuttles to Florence, SC and to Charlotte
