Bus Florence, SC to Charlotte: Compare prices and save money

Compare all timetables for the bus from Florence, SC to Charlotte

Here is a selection of the cheapest bus trips from the schedule from Florence, SC to Charlotte from various bus operators like FlixBus or Greyhound US for the next days.

today

tomorrow

$23

Monday

$23

Tuesday

$19

Wednesday

Thursday

$18

Friday

$19

Cheapest bus trips tomorrow
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	2h 45m	2:00 PM	Florence, SC	Bus Station	4:45 PM	Charlotte	W Trade St		Economy	$23	A Bus from FlixBus goes from Bus Station, Florence, SC (USA) at 6/21/2026 2:00:00 PM to W Trade St, Charlotte (USA) arriving at 6/21/2026 4:45:00 PM. 50 Economy ticket for $23 per person are available. Travel duration is 2h 45m
	Greyhound US	5h 40m	4:30 PM	Florence, SC	Bus Station	10:10 PM	Charlotte	W Trade St		Economy	$42	A Bus from Greyhound US goes from Bus Station, Florence, SC (USA) at 6/21/2026 4:30:00 PM to W Trade St, Charlotte (USA) arriving at 6/21/2026 10:10:00 PM. 50 Economy ticket for $42 per person are available. Travel duration is 5h 40m

Cheapest bus trips Monday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	2h 45m	2:00 PM	Florence, SC	Bus Station	4:45 PM	Charlotte	W Trade St		Economy	$23	A Bus from FlixBus goes from Bus Station, Florence, SC (USA) at 6/22/2026 2:00:00 PM to W Trade St, Charlotte (USA) arriving at 6/22/2026 4:45:00 PM. 50 Economy ticket for $23 per person are available. Travel duration is 2h 45m
	Greyhound US	5h 40m	4:30 PM	Florence, SC	Bus Station	10:10 PM	Charlotte	W Trade St		Economy	$48	A Bus from Greyhound US goes from Bus Station, Florence, SC (USA) at 6/22/2026 4:30:00 PM to W Trade St, Charlotte (USA) arriving at 6/22/2026 10:10:00 PM. 50 Economy ticket for $48 per person are available. Travel duration is 5h 40m

Cheapest bus trips Tuesday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	2h 45m	2:00 PM	Florence, SC	Bus Station	4:45 PM	Charlotte	W Trade St		Economy	$19	A Bus from FlixBus goes from Bus Station, Florence, SC (USA) at 6/23/2026 2:00:00 PM to W Trade St, Charlotte (USA) arriving at 6/23/2026 4:45:00 PM. 50 Economy ticket for $19 per person are available. Travel duration is 2h 45m
	Greyhound US	5h 40m	4:30 PM	Florence, SC	Bus Station	10:10 PM	Charlotte	W Trade St		Economy	$36	A Bus from Greyhound US goes from Bus Station, Florence, SC (USA) at 6/23/2026 4:30:00 PM to W Trade St, Charlotte (USA) arriving at 6/23/2026 10:10:00 PM. 50 Economy ticket for $36 per person are available. Travel duration is 5h 40m

Cheapest bus trips Thursday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	2h 45m	2:00 PM	Florence, SC	Bus Station	4:45 PM	Charlotte	W Trade St		Economy	$18	A Bus from FlixBus goes from Bus Station, Florence, SC (USA) at 6/25/2026 2:00:00 PM to W Trade St, Charlotte (USA) arriving at 6/25/2026 4:45:00 PM. 50 Economy ticket for $18 per person are available. Travel duration is 2h 45m
	Greyhound US	5h 40m	4:30 PM	Florence, SC	Bus Station	10:10 PM	Charlotte	W Trade St		Economy	$32	A Bus from Greyhound US goes from Bus Station, Florence, SC (USA) at 6/25/2026 4:30:00 PM to W Trade St, Charlotte (USA) arriving at 6/25/2026 10:10:00 PM. 50 Economy ticket for $32 per person are available. Travel duration is 5h 40m

Cheapest bus trips Friday
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	FlixBus	2h 45m	2:00 PM	Florence, SC	Bus Station	4:45 PM	Charlotte	W Trade St		Economy	$19	A Bus from FlixBus goes from Bus Station, Florence, SC (USA) at 6/26/2026 2:00:00 PM to W Trade St, Charlotte (USA) arriving at 6/26/2026 4:45:00 PM. 50 Economy ticket for $19 per person are available. Travel duration is 2h 45m
	Greyhound US	5h 40m	4:30 PM	Florence, SC	Bus Station	10:10 PM	Charlotte	W Trade St		Economy	$35	A Bus from Greyhound US goes from Bus Station, Florence, SC (USA) at 6/26/2026 4:30:00 PM to W Trade St, Charlotte (USA) arriving at 6/26/2026 10:10:00 PM. 50 Economy ticket for $35 per person are available. Travel duration is 5h 40m

Best Price Offer: The price for the cheapest bus from Florence, SC to Charlotte is $18 on 6/25/2026. Flexible travelers save on ticket prices.

Facts about the bus from Florence, SC to Charlotte

Compare all providers like FlixBus and Greyhound US that travel 2 times every day by bus from Florence, SC to Charlotte in one click! Book your bus ticket from Florence, SC to Charlotte starting from $18!

Cheapest Bus	$18
Fastest Bus	2h 45m
Earliest Bus	2:00 PM
Latest Bus	4:30 PM
Daily Bus Routes	2 Ø
Distance	93.5 miles
Bus Companies	FlixBus and Greyhound US

Cheapest bus connections from Florence, SC to Charlotte

Every day, 2 buses from 2 bus companies leave Florence, SC for Charlotte: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 06/20/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 06/14

Monday 06/15

Tuesday 06/16

Wednesday 06/17

Thursday 06/18

Friday 06/19

Saturday 06/20

Sunday 06/21

$27

Monday 06/22

$23

Tuesday 06/23

$19

Wednesday 06/24

Thursday 06/25

$18

Friday 06/26

$19

Saturday 06/27

$23

Sunday 06/28

Monday 06/29

Tuesday 06/30

Wednesday 07/01

Thursday 07/02

Friday 07/03

Saturday 07/04

Sunday 07/05

Monday 07/06

Tuesday 07/07

Wednesday 07/08

Thursday 07/09

Friday 07/10

Saturday 07/11

How to save money travelling from Florence, SC to Charlotte

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Florence, SC to Charlotte in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Florence, SC to Charlotte, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Florence, SC to Charlotte are also emptier.

All bus stations and stops in Florence, SC and Charlotte

In the map below, you can see where to find all bus stations in Florence, SC and Charlotte.

Bus Station

S Irby St 611

TA Travel Center

W Lucas St 2301

Exxon Gas Station

W Lucas Street 1901

McDonalds

W. Lucas St. 1908

Shell Gas Station

W Lucas Street 1832

W Trade St

W Trade St 601

Freedom Drive 3301

Freedom Dr 3301

Central Bus Station

Arrowood Light Rail Station

South Blvd 7430

Church St

S Church St 330

Service and Comfort on the bus from Florence, SC to Charlotte

Want to know which seat classes are available on the buses from Florence, SC to Charlotte? Or which bus companies serve the route Florence, SC to Charlotte? Below you will find answers to your questions.

FAQs about the Florence, SC to Charlotte bus

How much does a Florence, SC Charlotte bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $18 and takes 2h 45m to reach Charlotte. Compare offers to save money!

How much could I save by comparing buses from Florence, SC to Charlotte?

This route is offered by 2 companies with a range of ticket prices between $18 and $48. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Charlotte.

On average, how many connections are available from Florence, SC to Charlotte each day?

Every day, the Florence, SC to Charlotte bus route is served by approximately 2 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Florence, SC to Charlotte take?

The fastest bus from Florence, SC to Charlotte is offered by FlixBus and takes 2h 45m. Bus tickets for this connection cost $23. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Florence, SC to Charlotte?

The earliest bus arriving in Charlotte from Florence, SC starts at 2:00 PM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Florence, SC to Charlotte?

The latest bus trip departing from Florence, SC for Charlotte starts at 4:30 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Florence, SC Charlotte route?

When traveling by bus from Florence, SC to Charlotte, passengers can travel with FlixBus and Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Florence, SC and Charlotte?

You can check all the direct connections between Florence, SC and Charlotte by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: FlixBus and Greyhound US.

What can I take with me on the Florence, SC to Charlotte bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Florence, SC Charlotte bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Florence, SC Charlotte bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Florence, SC to Charlotte on your planned travel date.

How does CheckMyBus find the best bus deals from Florence, SC to Charlotte?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 2 daily trips between Florence, SC and Charlotte. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Florence, SC to Charlotte?

Prices and availability for 2 trips between Florence, SC and Charlotte change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Florence, SC to Charlotte

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Florence, SC and to Charlotte

Here’s an overview of the most popular bus routes to Florence, SC and to Charlotte. Simply click on the connection of your choice, and you will find all the details about your bus route!