Bus Washington, DC to Florence, SC: Compare prices and save money

Compare all timetables for the bus from Washington, DC to Florence, SC

Here is a selection of the cheapest bus trips from the schedule from Washington, DC to Florence, SC from various bus operators like Greyhound US, Wanda Coach or FlixBus for the next days.

today

tomorrow

$59

Thursday

$60

Friday

$64

Saturday

$59

Sunday

$69

Monday

Cheapest bus trips tomorrow
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	7h 55m	3:50 AM	Washington, DC	Union Station	11:45 AM	Florence, SC	Bus Station	Economy	$59	A Bus from Greyhound US goes from Union Station, Washington, DC (USA) at 6/24/2026 3:50:00 AM to Bus Station, Florence, SC (USA) arriving at 6/24/2026 11:45:00 AM. 50 Economy ticket for $59 per person are available. Travel duration is 7h 55m
Greyhound US	12h 0m	11:45 PM	Washington, DC	Union Station	11:45 AM	Florence, SC	Bus Station	Economy	$59	A Bus from Greyhound US goes from Union Station, Washington, DC (USA) at 6/24/2026 11:45:00 PM to Bus Station, Florence, SC (USA) arriving at 6/25/2026 11:45:00 AM. 50 Economy ticket for $59 per person are available. Travel duration is 12h 0m
FlixBus	8h 0m	9:45 PM	Washington, DC	Union Station	5:45 AM	Florence, SC	TA Travel Center	Economy	$82	A Bus from FlixBus goes from Union Station, Washington, DC (USA) at 6/24/2026 9:45:00 PM to TA Travel Center, Florence, SC (USA) arriving at 6/25/2026 5:45:00 AM. 50 Economy ticket for $82 per person are available. Travel duration is 8h 0m
Wanda Coach	7h 59m	12:01 AM	Washington, DC	Benning Rd NE	8:00 AM	Florence, SC	Shell Gas Station	Economy	$100	A Bus from Wanda Coach goes from Benning Rd NE, Washington, DC (USA) at 6/24/2026 12:01:00 AM to Shell Gas Station, Florence, SC (USA) arriving at 6/24/2026 8:00:00 AM. 50 Economy ticket for $100 per person are available. Travel duration is 7h 59m

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	12h 0m	11:45 PM	Washington, DC	Union Station	11:45 AM	Florence, SC	Bus Station	Economy	$60	A Bus from Greyhound US goes from Union Station, Washington, DC (USA) at 6/25/2026 11:45:00 PM to Bus Station, Florence, SC (USA) arriving at 6/26/2026 11:45:00 AM. 50 Economy ticket for $60 per person are available. Travel duration is 12h 0m
FlixBus	8h 0m	9:45 PM	Washington, DC	Union Station	5:45 AM	Florence, SC	TA Travel Center	Economy	$65	A Bus from FlixBus goes from Union Station, Washington, DC (USA) at 6/25/2026 9:45:00 PM to TA Travel Center, Florence, SC (USA) arriving at 6/26/2026 5:45:00 AM. 50 Economy ticket for $65 per person are available. Travel duration is 8h 0m
Greyhound US	7h 55m	3:50 AM	Washington, DC	Union Station	11:45 AM	Florence, SC	Bus Station	Economy	$88	A Bus from Greyhound US goes from Union Station, Washington, DC (USA) at 6/25/2026 3:50:00 AM to Bus Station, Florence, SC (USA) arriving at 6/25/2026 11:45:00 AM. 50 Economy ticket for $88 per person are available. Travel duration is 7h 55m
Wanda Coach	7h 59m	12:01 AM	Washington, DC	Exxon New York Ave NE	8:00 AM	Florence, SC	Exxon Gas Station	Economy	$100	A Bus from Wanda Coach goes from Exxon New York Ave NE, Washington, DC (USA) at 6/25/2026 12:01:00 AM to Exxon Gas Station, Florence, SC (USA) arriving at 6/25/2026 8:00:00 AM. 50 Economy ticket for $100 per person are available. Travel duration is 7h 59m

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	7h 55m	3:50 AM	Washington, DC	Union Station	11:45 AM	Florence, SC	Bus Station	Economy	$64	A Bus from Greyhound US goes from Union Station, Washington, DC (USA) at 6/26/2026 3:50:00 AM to Bus Station, Florence, SC (USA) arriving at 6/26/2026 11:45:00 AM. 50 Economy ticket for $64 per person are available. Travel duration is 7h 55m
Greyhound US	12h 0m	11:45 PM	Washington, DC	Union Station	11:45 AM	Florence, SC	Bus Station	Economy	$64	A Bus from Greyhound US goes from Union Station, Washington, DC (USA) at 6/26/2026 11:45:00 PM to Bus Station, Florence, SC (USA) arriving at 6/27/2026 11:45:00 AM. 50 Economy ticket for $64 per person are available. Travel duration is 12h 0m
Wanda Coach	7h 59m	12:01 AM	Washington, DC	Exxon New York Ave NE	8:00 AM	Florence, SC	Exxon Gas Station	Economy	$100	A Bus from Wanda Coach goes from Exxon New York Ave NE, Washington, DC (USA) at 6/26/2026 12:01:00 AM to Exxon Gas Station, Florence, SC (USA) arriving at 6/26/2026 8:00:00 AM. 50 Economy ticket for $100 per person are available. Travel duration is 7h 59m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	13h 35m	10:10 PM	Washington, DC	Union Station	11:45 AM	Florence, SC	Bus Station	Economy	$59	A Bus from Greyhound US goes from Union Station, Washington, DC (USA) at 6/27/2026 10:10:00 PM to Bus Station, Florence, SC (USA) arriving at 6/28/2026 11:45:00 AM. 50 Economy ticket for $59 per person are available. Travel duration is 13h 35m
FlixBus	8h 0m	9:45 PM	Washington, DC	Union Station	5:45 AM	Florence, SC	TA Travel Center	Economy	$71	A Bus from FlixBus goes from Union Station, Washington, DC (USA) at 6/27/2026 9:45:00 PM to TA Travel Center, Florence, SC (USA) arriving at 6/28/2026 5:45:00 AM. 50 Economy ticket for $71 per person are available. Travel duration is 8h 0m
Greyhound US	8h 5m	3:40 AM	Washington, DC	Union Station	11:45 AM	Florence, SC	Bus Station	Economy	$72	A Bus from Greyhound US goes from Union Station, Washington, DC (USA) at 6/27/2026 3:40:00 AM to Bus Station, Florence, SC (USA) arriving at 6/27/2026 11:45:00 AM. 50 Economy ticket for $72 per person are available. Travel duration is 8h 5m
Wanda Coach	7h 59m	12:01 AM	Washington, DC	Benning Rd NE	8:00 AM	Florence, SC	Shell Gas Station	Economy	$100	A Bus from Wanda Coach goes from Benning Rd NE, Washington, DC (USA) at 6/27/2026 12:01:00 AM to Shell Gas Station, Florence, SC (USA) arriving at 6/27/2026 8:00:00 AM. 50 Economy ticket for $100 per person are available. Travel duration is 7h 59m

Cheapest bus trips Sunday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	7h 55m	3:50 AM	Washington, DC	Union Station	11:45 AM	Florence, SC	Bus Station	Economy	$69	A Bus from Greyhound US goes from Union Station, Washington, DC (USA) at 6/28/2026 3:50:00 AM to Bus Station, Florence, SC (USA) arriving at 6/28/2026 11:45:00 AM. 50 Economy ticket for $69 per person are available. Travel duration is 7h 55m
Greyhound US	12h 0m	11:45 PM	Washington, DC	Union Station	11:45 AM	Florence, SC	Bus Station	Economy	$69	A Bus from Greyhound US goes from Union Station, Washington, DC (USA) at 6/28/2026 11:45:00 PM to Bus Station, Florence, SC (USA) arriving at 6/29/2026 11:45:00 AM. 50 Economy ticket for $69 per person are available. Travel duration is 12h 0m
FlixBus	8h 0m	9:45 PM	Washington, DC	Union Station	5:45 AM	Florence, SC	TA Travel Center	Economy	$86	A Bus from FlixBus goes from Union Station, Washington, DC (USA) at 6/28/2026 9:45:00 PM to TA Travel Center, Florence, SC (USA) arriving at 6/29/2026 5:45:00 AM. 50 Economy ticket for $86 per person are available. Travel duration is 8h 0m

Did you know that if you travel from Washington, DC to Florence, SC via Raleigh, NC, you can save more than $8? You can find the corresponding connections below.
- CoachRun
  
  10h 5m
  
  0
  
  1:40 AM
  
  Washington, DC
  Pennsylvania Av SE & L'Enfant Sq SE Bus Stop
  
  6:20 AM
  
  Raleigh, NC
  Wilmington St Service Rd at Chapanoke Rd
  
  0
  
  Economy
  
  $38
  
  A Bus from CoachRun goes from Pennsylvania Av SE & L'Enfant Sq SE Bus Stop, Washington, DC (USA) at 6/27/2026 1:40:00 AM to Wilmington St Service Rd at Chapanoke Rd, Raleigh, NC (USA) arriving at 6/27/2026 6:20:00 AM. 50 Economy ticket for $38 per person are available. Travel duration is 4h 40m
- Greyhound US
  
  2h 50m
  
  0
  
  8:55 AM
  
  Raleigh, NC
  Greyhound Bus Station
  
  11:45 AM
  
  Florence, SC
  Bus Station
  
  0
  
  Economy
  
  $23
  
  A Bus from Greyhound US goes from Greyhound Bus Station, Raleigh, NC (USA) at 6/27/2026 8:55:00 AM to Bus Station, Florence, SC (USA) arriving at 6/27/2026 11:45:00 AM. 50 Economy ticket for $23 per person are available. Travel duration is 2h 50m
Travel time is 2h 10m longer, but you will save $8

Best Price Offer: The price for the cheapest bus from Washington, DC to Florence, SC is $48 on 7/14/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Washington, DC and Florence, SC

See here how frequent the connections between Washington, DC and Florence, SC are, during different times and days of the week.

Thursday is the busiest day, with more than 7 daily buses from Washington, DC to Florence, SC. Sunday has instead the fewest connections, with only 3 daily coaches between Washington, DC and Florence, SC.

The busiest time of the day is the Night, with 15 buses from Washington, DC to Florence, SC, while Evening sees the fewest connections between Washington, DC and Florence, SC, with 11 offers.

Facts about the bus from Washington, DC to Florence, SC

Compare all providers like Greyhound US, Wanda Coach and FlixBus that travel 5 times every day by bus from Washington, DC to Florence, SC in one click! Book your bus ticket from Washington, DC to Florence, SC starting from $48!

Cheapest Bus	$48
Fastest Bus	7h 55m
Earliest Bus	12:01 AM
Latest Bus	11:45 PM
Daily Bus Routes	5 Ø
Distance	359.2 miles
Bus Companies	Greyhound US, Wanda Coach and FlixBus

Cheapest bus connections from Washington, DC to Florence, SC

Every day, 5 buses from 3 bus companies leave Washington, DC for Florence, SC: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 06/23/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 06/21

Monday 06/22

Tuesday 06/23

$100

Wednesday 06/24

$100

Thursday 06/25

$100

Friday 06/26

$100

Saturday 06/27

$100

Sunday 06/28

$69

Monday 06/29

Tuesday 06/30

Wednesday 07/01

Thursday 07/02

Friday 07/03

Saturday 07/04

Sunday 07/05

Monday 07/06

Tuesday 07/07

Wednesday 07/08

Thursday 07/09

Friday 07/10

$100

Saturday 07/11

$100

Sunday 07/12

$63

Monday 07/13

$100

Tuesday 07/14

$48

Wednesday 07/15

$51

Thursday 07/16

$100

Friday 07/17

$100

Saturday 07/18

The cheapest time to travel from Washington, DC to Florence, SC

See here on which day and which time of the day you can find the cheapest bus ticket from Washington, DC to Florence, SC, for the next 30 days.

With a price starting from $51, Wednesday is the cheapest day for a bus from Washington, DC to Florence, SC. Friday instead is the most expensive day with prices starting from $64.

Night is the cheapest day time for bus tickets from Washington, DC to Florence, SC, with $48. Evening is the most expensive time of the day with prices starting from $59.

How to save money travelling from Washington, DC to Florence, SC

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Washington, DC to Florence, SC in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Washington, DC to Florence, SC, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Washington, DC to Florence, SC are also emptier.

Beloved bus companies from Washington, DC to Florence, SC

These are the most booked bus companies between Washington, DC to Florence, SC from our users.

Greyhound US from Washington, DC to Florence, SC

Here you will find the key facts about the Greyhound US bus route Washington, DC to Florence, SC:

Cheapest Price	$59
Fastest Bus	7h 55m
Earliest Bus	3:50 AM
Last Bus	11:45 PM
Daily Connections	2 Ø
Found on	5/29/2026

FlixBus from Washington, DC to Florence, SC

Here you will find the key facts about the FlixBus bus route Washington, DC to Florence, SC:

Cheapest Price	$65
Fastest Bus	8h 0m
Earliest Bus	9:45 PM
Last Bus	9:45 PM
Daily Connections	1 Ø
Found on	5/29/2026

All bus stations and stops in Washington, DC and Florence, SC

In the map below, you can see where to find all bus stations in Washington, DC and Florence, SC.

Union Station

Massachusetts Avenue Northeast 50

Dupont Circle Station

20th St. NW 1525

Metro Center

11th St NW 663

L'Enfant Plaza outside McDonald's

C Street SW DC 400 C Street SW, Washington, DC 400

Chinatown H St NW

H St NW 715

Bus Station

S Irby St 611

Exxon Gas Station

W Lucas Street 1901

McDonalds

W. Lucas St. 1908

Shell Gas Station

W Lucas Street 1832

South Carolina Federal Gas Station

Service and Comfort on the bus from Washington, DC to Florence, SC

Want to know which seat classes are available on the buses from Washington, DC to Florence, SC? Or which bus companies serve the route Washington, DC to Florence, SC? Below you will find answers to your questions.

FAQs about the Washington, DC to Florence, SC bus

How much does a Washington, DC Florence, SC bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $48 and takes 7h 55m to reach Florence, SC. Compare offers to save money!

How much could I save by comparing buses from Washington, DC to Florence, SC?

This route is offered by 3 companies with a range of ticket prices between $48 and $103. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Florence, SC.

On average, how many connections are available from Washington, DC to Florence, SC each day?

Every day, the Washington, DC to Florence, SC bus route is served by approximately 5 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Washington, DC to Florence, SC take?

The fastest bus from Washington, DC to Florence, SC is offered by Greyhound US and takes 7h 55m. Bus tickets for this connection cost $59. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Washington, DC to Florence, SC?

The earliest bus arriving in Florence, SC from Washington, DC starts at 12:01 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Washington, DC to Florence, SC?

The latest bus trip departing from Washington, DC for Florence, SC starts at 11:45 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Washington, DC Florence, SC route?

When traveling by bus from Washington, DC to Florence, SC, passengers can travel with Greyhound US, Wanda Coach and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Washington, DC and Florence, SC?

You can check all the direct connections between Washington, DC and Florence, SC by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US, Wanda Coach and FlixBus.

What can I take with me on the Washington, DC to Florence, SC bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Washington, DC Florence, SC bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Washington, DC Florence, SC bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Washington, DC to Florence, SC on your planned travel date.

How does CheckMyBus find the best bus deals from Washington, DC to Florence, SC?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 5 daily trips between Washington, DC and Florence, SC. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Washington, DC to Florence, SC?

Prices and availability for 5 trips between Washington, DC and Florence, SC change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Washington, DC to Florence, SC

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Washington, DC and to Florence, SC

Here’s an overview of the most popular bus routes to Washington, DC and to Florence, SC. Simply click on the connection of your choice, and you will find all the details about your bus route!