Bus Tallahassee, FL to Florence, SC: Compare prices and save money

Compare all timetables for the bus from Tallahassee, FL to Florence, SC

Here is a selection of the cheapest bus trips from the schedule from Tallahassee, FL to Florence, SC from various bus operators like Greyhound US for the next days.

today

$87

tomorrow

Wednesday

Thursday

$85

Friday

$85

Saturday

$78

Sunday

Cheapest bus trips today
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	12h 40m	11:25 AM	Tallahassee, FL	Greyhound Bus Station	12:05 AM	Florence, SC	TA Travel Center	Economy	$87	A Bus from Greyhound US goes from Greyhound Bus Station, Tallahassee, FL (USA) at 4/27/2026 11:25:00 AM to TA Travel Center, Florence, SC (USA) arriving at 4/28/2026 12:05:00 AM. 50 Economy ticket for $87 per person are available. Travel duration is 12h 40m
Greyhound US	16h 20m	9:05 PM	Tallahassee, FL	Greyhound Bus Station	1:25 PM	Florence, SC	Bus Station	Economy	$87	A Bus from Greyhound US goes from Greyhound Bus Station, Tallahassee, FL (USA) at 4/27/2026 9:05:00 PM to Bus Station, Florence, SC (USA) arriving at 4/28/2026 1:25:00 PM. 50 Economy ticket for $87 per person are available. Travel duration is 16h 20m
Greyhound US	22h 55m	12:50 PM	Tallahassee, FL	Greyhound Bus Station	11:45 AM	Florence, SC	Bus Station	Economy	$88	A Bus from Greyhound US goes from Greyhound Bus Station, Tallahassee, FL (USA) at 4/27/2026 12:50:00 PM to Bus Station, Florence, SC (USA) arriving at 4/28/2026 11:45:00 AM. 50 Economy ticket for $88 per person are available. Travel duration is 22h 55m

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	16h 20m	9:05 PM	Tallahassee, FL	Greyhound Bus Station	1:25 PM	Florence, SC	Bus Station	Economy	$85	A Bus from Greyhound US goes from Greyhound Bus Station, Tallahassee, FL (USA) at 4/30/2026 9:05:00 PM to Bus Station, Florence, SC (USA) arriving at 5/1/2026 1:25:00 PM. 50 Economy ticket for $85 per person are available. Travel duration is 16h 20m
Greyhound US	12h 40m	11:25 AM	Tallahassee, FL	Greyhound Bus Station	12:05 AM	Florence, SC	TA Travel Center	Economy	$86	A Bus from Greyhound US goes from Greyhound Bus Station, Tallahassee, FL (USA) at 4/30/2026 11:25:00 AM to TA Travel Center, Florence, SC (USA) arriving at 5/1/2026 12:05:00 AM. 50 Economy ticket for $86 per person are available. Travel duration is 12h 40m
Greyhound US	22h 55m	12:50 PM	Tallahassee, FL	Greyhound Bus Station	11:45 AM	Florence, SC	Bus Station	Economy	$86	A Bus from Greyhound US goes from Greyhound Bus Station, Tallahassee, FL (USA) at 4/30/2026 12:50:00 PM to Bus Station, Florence, SC (USA) arriving at 5/1/2026 11:45:00 AM. 50 Economy ticket for $86 per person are available. Travel duration is 22h 55m

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	22h 55m	12:50 PM	Tallahassee, FL	Greyhound Bus Station	11:45 AM	Florence, SC	Bus Station	Economy	$85	A Bus from Greyhound US goes from Greyhound Bus Station, Tallahassee, FL (USA) at 5/1/2026 12:50:00 PM to Bus Station, Florence, SC (USA) arriving at 5/2/2026 11:45:00 AM. 50 Economy ticket for $85 per person are available. Travel duration is 22h 55m
Greyhound US	16h 20m	9:05 PM	Tallahassee, FL	Greyhound Bus Station	1:25 PM	Florence, SC	Bus Station	Economy	$85	A Bus from Greyhound US goes from Greyhound Bus Station, Tallahassee, FL (USA) at 5/1/2026 9:05:00 PM to Bus Station, Florence, SC (USA) arriving at 5/2/2026 1:25:00 PM. 50 Economy ticket for $85 per person are available. Travel duration is 16h 20m
Greyhound US	12h 40m	11:25 AM	Tallahassee, FL	Greyhound Bus Station	12:05 AM	Florence, SC	TA Travel Center	Economy	$86	A Bus from Greyhound US goes from Greyhound Bus Station, Tallahassee, FL (USA) at 5/1/2026 11:25:00 AM to TA Travel Center, Florence, SC (USA) arriving at 5/2/2026 12:05:00 AM. 50 Economy ticket for $86 per person are available. Travel duration is 12h 40m

Cheapest bus trips Saturday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	12h 40m	11:25 AM	Tallahassee, FL	Greyhound Bus Station	12:05 AM	Florence, SC	TA Travel Center	Economy	$78	A Bus from Greyhound US goes from Greyhound Bus Station, Tallahassee, FL (USA) at 5/2/2026 11:25:00 AM to TA Travel Center, Florence, SC (USA) arriving at 5/3/2026 12:05:00 AM. 50 Economy ticket for $78 per person are available. Travel duration is 12h 40m
Greyhound US	16h 20m	9:05 PM	Tallahassee, FL	Greyhound Bus Station	1:25 PM	Florence, SC	Bus Station	Economy	$78	A Bus from Greyhound US goes from Greyhound Bus Station, Tallahassee, FL (USA) at 5/2/2026 9:05:00 PM to Bus Station, Florence, SC (USA) arriving at 5/3/2026 1:25:00 PM. 50 Economy ticket for $78 per person are available. Travel duration is 16h 20m
Greyhound US	22h 55m	12:50 PM	Tallahassee, FL	Greyhound Bus Station	11:45 AM	Florence, SC	Bus Station	Economy	$79	A Bus from Greyhound US goes from Greyhound Bus Station, Tallahassee, FL (USA) at 5/2/2026 12:50:00 PM to Bus Station, Florence, SC (USA) arriving at 5/3/2026 11:45:00 AM. 50 Economy ticket for $79 per person are available. Travel duration is 22h 55m

Best Price Offer: The price for the cheapest bus from Tallahassee, FL to Florence, SC is $78 on 5/2/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Tallahassee, FL and Florence, SC

See here how frequent the connections between Tallahassee, FL and Florence, SC are, during different times and days of the week.

Monday is the busiest day, with more than 3 daily buses from Tallahassee, FL to Florence, SC. Monday has instead the fewest connections, with only 3 daily coaches between Tallahassee, FL and Florence, SC.

The busiest time of the day is the Morning, with 4 buses from Tallahassee, FL to Florence, SC, while Morning sees the fewest connections between Tallahassee, FL and Florence, SC, with 4 offers.

Facts about the bus from Tallahassee, FL to Florence, SC

Compare all providers like Greyhound US that travel 3 times every day by bus from Tallahassee, FL to Florence, SC in one click! Book your bus ticket from Tallahassee, FL to Florence, SC starting from $78!

Cheapest Bus	$78
Fastest Bus	12h 40m
Earliest Bus	11:25 AM
Latest Bus	9:05 PM
Daily Bus Routes	3 Ø
Distance	369.9 miles
Bus Companies	Greyhound US

Cheapest bus connections from Tallahassee, FL to Florence, SC

Every day, 3 buses from 1 bus companies leave Tallahassee, FL for Florence, SC: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 04/27/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 04/26

Monday 04/27

$87

Tuesday 04/28

Wednesday 04/29

Thursday 04/30

$85

Friday 05/01

$85

Saturday 05/02

$78

Sunday 05/03

Monday 05/04

Tuesday 05/05

Wednesday 05/06

Thursday 05/07

Friday 05/08

Saturday 05/09

Sunday 05/10

Monday 05/11

$78

Tuesday 05/12

Wednesday 05/13

$88

Thursday 05/14

Friday 05/15

$87

Saturday 05/16

$81

Sunday 05/17

$83

Monday 05/18

$84

Tuesday 05/19

$96

Wednesday 05/20

Thursday 05/21

$83

Friday 05/22

$89

Saturday 05/23

The cheapest time to travel from Tallahassee, FL to Florence, SC

See here on which day and which time of the day you can find the cheapest bus ticket from Tallahassee, FL to Florence, SC, for the next 30 days.

With a price starting from $78, Saturday is the cheapest day for a bus from Tallahassee, FL to Florence, SC. Friday instead is the most expensive day with prices starting from $85.

Morning is the cheapest day time for bus tickets from Tallahassee, FL to Florence, SC, with $78. Afternoon is the most expensive time of the day with prices starting from $79.

How to save money travelling from Tallahassee, FL to Florence, SC

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Tallahassee, FL to Florence, SC in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Tallahassee, FL to Florence, SC, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Tallahassee, FL to Florence, SC are also emptier.

All bus stations and stops in Tallahassee, FL and Florence, SC

In the map below, you can see where to find all bus stations in Tallahassee, FL and Florence, SC.

Downtown RedCoach Stop

Marriott Dr 329

FSU

West Virginia St

FSU Stadium

Champions Way 284

Old St Augustine at Intramural Field Bus Stop

Old St Augustine at Intramural Field Old St Augustine at Intramural Field

La Moreliana

Bus Station

S Irby St 611

TA Travel Center

W Lucas St 2301

Exxon Gas Station

W Lucas Street 1901

McDonalds

W. Lucas St. 1908

Shell Gas Station

W Lucas Street 1832

Service and Comfort on the bus from Tallahassee, FL to Florence, SC

Want to know which seat classes are available on the buses from Tallahassee, FL to Florence, SC? Or which bus companies serve the route Tallahassee, FL to Florence, SC? Below you will find answers to your questions.

FAQs about the Tallahassee, FL to Florence, SC bus

How much does a Tallahassee, FL Florence, SC bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $78 and takes 12h 40m to reach Florence, SC. Compare offers to save money!

How much could I save by comparing buses from Tallahassee, FL to Florence, SC?

This route is offered by 1 companies with a range of ticket prices between $78 and $88. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Florence, SC.

On average, how many connections are available from Tallahassee, FL to Florence, SC each day?

Every day, the Tallahassee, FL to Florence, SC bus route is served by approximately 3 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Tallahassee, FL to Florence, SC take?

The fastest bus from Tallahassee, FL to Florence, SC is offered by Greyhound US and takes 12h 40m. Bus tickets for this connection cost $87. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Tallahassee, FL to Florence, SC?

The earliest bus arriving in Florence, SC from Tallahassee, FL starts at 11:25 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Tallahassee, FL to Florence, SC?

The latest bus trip departing from Tallahassee, FL for Florence, SC starts at 9:05 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Tallahassee, FL Florence, SC route?

When traveling by bus from Tallahassee, FL to Florence, SC, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Tallahassee, FL and Florence, SC?

You can check all the direct connections between Tallahassee, FL and Florence, SC by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Tallahassee, FL to Florence, SC bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Tallahassee, FL Florence, SC bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Tallahassee, FL Florence, SC bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Tallahassee, FL to Florence, SC on your planned travel date.

How does CheckMyBus find the best bus deals from Tallahassee, FL to Florence, SC?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 3 daily trips between Tallahassee, FL and Florence, SC. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Tallahassee, FL to Florence, SC?

Prices and availability for 3 trips between Tallahassee, FL and Florence, SC change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Tallahassee, FL to Florence, SC

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Tallahassee, FL and to Florence, SC

Here’s an overview of the most popular bus routes to Tallahassee, FL and to Florence, SC. Simply click on the connection of your choice, and you will find all the details about your bus route!