Bus from Phoenix, AZ to Florence, SC from $138

Compare all the bus companies and find the best price with CheckMyBus
The Best Deals Save up to 70%
The Most Choices Millions of routes worldwide
Easy and Transparent Compare offers with 1 click

Compare all timetables for the bus from Phoenix, AZ to Florence, SC

Here is a selection of the cheapest bus trips from the schedule from Phoenix, AZ to Florence, SC from various bus operators like Greyhound US or FlixBus for the next days.

today
$142
tomorrow
$148
Sunday
$217
Monday
$217
Tuesday
$225
Wednesday
Thursday

Cheapest bus trips today

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 51h 20m 5:45 PM Phoenix, AZ Bus Station 12:05 AM Florence, SC TA Travel Center  Economy $142
Greyhound US 61h 45m 7:20 AM Phoenix, AZ 44th St/Washington 12:05 AM Florence, SC TA Travel Center  Economy $145
FlixBus 80h 40m 12:25 PM Phoenix, AZ 44th St/Washington 12:05 AM Florence, SC TA Travel Center  Economy $147
Greyhound US 50h 50m 7:40 AM Phoenix, AZ Bus Station 1:30 PM Florence, SC Bus Station  Economy $221

Cheapest bus trips tomorrow

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 61h 45m 7:20 AM Phoenix, AZ 44th St/Washington 12:05 AM Florence, SC TA Travel Center  Economy $148
Greyhound US 51h 20m 5:45 PM Phoenix, AZ Bus Station 12:05 AM Florence, SC TA Travel Center  Economy $157

Cheapest bus trips Sunday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 50h 50m 7:40 AM Phoenix, AZ Bus Station 1:30 PM Florence, SC Bus Station  Economy $217
Greyhound US 58h 10m 10:45 PM Phoenix, AZ Bus Station 11:55 AM Florence, SC Bus Station  Economy $227
  • Did you know that if you travel from Phoenix, AZ to Florence, SC via Glendale, AZ, you can save more than $-6? You will find the corresponding connections below.
    • 57h 50m
      Phoenix, AZ
      9 mi
      11:05 PM
      Glendale, AZ
      Central Bus Station
      11:55 AM
      Florence, SC
      Bus Station
      0 mi
      Economy
      $223
  • Did you know that if you travel from Phoenix, AZ to Florence, SC via Atlanta, GA, you can save more than $52? You can find the corresponding connections below.
    • Greyhound US
      74h 50m
      0
      7:40 AM
      Phoenix, AZ
      Bus Station
      2:40 AM
      Atlanta, GA
      Garnett Transit Station
      0
      Greyhound US
      Economy
      $132
      • Waiting Time 28h 30m
    • Greyhound US
      6h 20m
      0
      7:10 AM
      Atlanta, GA
      Garnett Transit Station
      1:30 PM
      Florence, SC
      Bus Station
      0
      Greyhound US
      Economy
      $33
    Travel time is 21h 0m longer, but you will save $52

Cheapest bus trips Monday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 50h 50m 7:40 AM Phoenix, AZ Bus Station 1:30 PM Florence, SC Bus Station  Economy $217
Greyhound US 58h 10m 10:45 PM Phoenix, AZ Bus Station 11:55 AM Florence, SC Bus Station  Economy $228
  • Did you know that if you travel from Phoenix, AZ to Florence, SC via Glendale, AZ, you can save more than $-9? You will find the corresponding connections below.
    • 57h 50m
      Phoenix, AZ
      9 mi
      11:05 PM
      Glendale, AZ
      Central Bus Station
      11:55 AM
      Florence, SC
      Bus Station
      0 mi
      Economy
      $226
  • Did you know that if you travel from Phoenix, AZ to Florence, SC via Atlanta, GA, you can save more than $52? You can find the corresponding connections below.
    • Greyhound US
      74h 50m
      0
      7:40 AM
      Phoenix, AZ
      Bus Station
      2:40 AM
      Atlanta, GA
      Garnett Transit Station
      0
      Greyhound US
      Economy
      $132
      • Waiting Time 28h 30m
    • Greyhound US
      6h 20m
      0
      7:10 AM
      Atlanta, GA
      Garnett Transit Station
      1:30 PM
      Florence, SC
      Bus Station
      0
      Greyhound US
      Economy
      $33
    Travel time is 21h 0m longer, but you will save $52

Cheapest bus trips Tuesday

Mode of Transport BertCompanyCountOneCompanyName Duration Departure time From Departure Arrival time To Destination Logo Seat classes Price
Greyhound US 58h 10m 10:45 PM Phoenix, AZ Bus Station 11:55 AM Florence, SC Bus Station  Economy $225
Greyhound US 50h 50m 7:40 AM Phoenix, AZ Bus Station 1:30 PM Florence, SC Bus Station  Economy $228
  • Did you know that if you travel from Phoenix, AZ to Florence, SC via Glendale, AZ, you can save more than $-1? You will find the corresponding connections below.
    • Save more than 1%
      57h 50m
      Phoenix, AZ
      9 mi
      11:05 PM
      Glendale, AZ
      Central Bus Station
      11:55 AM
      Florence, SC
      Bus Station
      0 mi
      Economy
      $226
  • Did you know that if you travel from Phoenix, AZ to Florence, SC via Atlanta, GA, you can save more than $60? You can find the corresponding connections below.
    • Greyhound US
      74h 50m
      0
      7:40 AM
      Phoenix, AZ
      Bus Station
      2:40 AM
      Atlanta, GA
      Garnett Transit Station
      0
      Greyhound US
      Economy
      $132
      • Waiting Time 28h 30m
    • Greyhound US
      6h 20m
      0
      7:10 AM
      Atlanta, GA
      Garnett Transit Station
      1:30 PM
      Florence, SC
      Bus Station
      0
      Greyhound US
      Economy
      $33
    Travel time is 21h 0m longer, but you will save $60

Best Price Offer: The price for the cheapest bus from Phoenix, AZ to Florence, SC is $138 on 10/16/2026. Flexible travelers save on ticket prices.


Frequency of bus connections between Phoenix, AZ and Florence, SC

See here how frequent the connections between Phoenix, AZ and Florence, SC are, during different times and days of the week.
Friday is the busiest day, with more than 5 daily buses from Phoenix, AZ to Florence, SC. Sunday has instead the fewest connections, with only 2 daily coaches between Phoenix, AZ and Florence, SC.
The busiest time of the day is the Morning, with 6 buses from Phoenix, AZ to Florence, SC, while Afternoon sees the fewest connections between Phoenix, AZ and Florence, SC, with 3 offers.

Facts about the bus from Phoenix, AZ to Florence, SC

Compare all providers like Greyhound US and FlixBus that travel 2 times every day by bus from Phoenix, AZ to Florence, SC in one click! Book your bus ticket from Phoenix, AZ to Florence, SC starting from $138!

Cheapest Bus $138
Fastest Bus 53h 50m
Earliest Bus 7:20 AM
Latest Bus 10:45 PM
Daily Bus Routes 2 Ø
Distance 1,848.2 miles
Bus Companies Greyhound US and FlixBus

Cheapest bus connections from Phoenix, AZ to Florence, SC

Every day, 2 buses from 2 bus companies leave Phoenix, AZ for Florence, SC: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 10/16/2026 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 10/11
Monday 10/12
Tuesday 10/13
Wednesday 10/14
Thursday 10/15
Friday 10/16
$138
Saturday 10/17
$148
Sunday 10/18
$217
Monday 10/19
$199
Tuesday 10/20
$195
Wednesday 10/21
Thursday 10/22
Friday 10/23
Saturday 10/24
$155
Sunday 10/25
$226
Monday 10/26
$159
Tuesday 10/27
$178
Wednesday 10/28
$194
Thursday 10/29
$189
Friday 10/30
Saturday 10/31
$152
Sunday 11/01
Monday 11/02
$161
Tuesday 11/03
Wednesday 11/04
$155
Thursday 11/05
$148
Friday 11/06
$160
Saturday 11/07

The cheapest time to travel from Phoenix, AZ to Florence, SC

See here on which day and which time of the day you can find the cheapest bus ticket from Phoenix, AZ to Florence, SC, for the next 30 days.
With a price starting from $133, Saturday is the cheapest day for a bus from Phoenix, AZ to Florence, SC. Sunday instead is the most expensive day with prices starting from $217.
Afternoon is the cheapest day time for bus tickets from Phoenix, AZ to Florence, SC, with $142. Evening is the most expensive time of the day with prices starting from $221.

How to save money travelling from Phoenix, AZ to Florence, SC

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Phoenix, AZ to Florence, SC in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Phoenix, AZ to Florence, SC, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Phoenix, AZ to Florence, SC are also emptier.

Beloved bus companies from Phoenix, AZ to Florence, SC

These are the most booked bus companies between Phoenix, AZ to Florence, SC from our users.

Greyhound US from Phoenix, AZ to Florence, SC

Greyhound US

Here you will find the key facts about the Greyhound US bus route Phoenix, AZ to Florence, SC:

Cheapest Price $142
Fastest Bus 53h 50m
Earliest Bus 7:20 AM
Last Bus 10:45 PM
Daily Connections 2 Ø
Found on 9/19/2026

All bus stations and stops in Phoenix, AZ and Florence, SC

In the map below, you can see where to find all bus stations in Phoenix, AZ and Florence, SC.

Service and Comfort on the bus from Phoenix, AZ to Florence, SC

Want to know which seat classes are available on the buses from Phoenix, AZ to Florence, SC? Or which bus companies serve the route Phoenix, AZ to Florence, SC? Below you will find answers to your questions.

FAQs about the Phoenix, AZ to Florence, SC bus

How much does a Phoenix, AZ Florence, SC bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $138 and takes 54h 20m to reach Florence, SC. Compare offers to save money!

How much could I save by comparing buses from Phoenix, AZ to Florence, SC?

This route is offered by 2 companies with a range of ticket prices between $138 and $228. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Florence, SC.

On average, how many connections are available from Phoenix, AZ to Florence, SC each day?

Every day, the Phoenix, AZ to Florence, SC bus route is served by approximately 2 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Phoenix, AZ to Florence, SC take?

The fastest bus from Phoenix, AZ to Florence, SC is offered by Greyhound US and takes 53h 50m. Bus tickets for this connection cost $221. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Phoenix, AZ to Florence, SC?

The earliest bus arriving in Florence, SC from Phoenix, AZ starts at 7:20 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Phoenix, AZ to Florence, SC?

The latest bus trip departing from Phoenix, AZ for Florence, SC starts at 10:45 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Phoenix, AZ Florence, SC route?

When traveling by bus from Phoenix, AZ to Florence, SC, passengers can travel with Greyhound US and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Phoenix, AZ and Florence, SC?

You can check all the direct connections between Phoenix, AZ and Florence, SC by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US and FlixBus.

What can I take with me on the Phoenix, AZ to Florence, SC bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Phoenix, AZ Florence, SC bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Phoenix, AZ Florence, SC bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Phoenix, AZ to Florence, SC on your planned travel date.

How does CheckMyBus find the best bus deals from Phoenix, AZ to Florence, SC?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 2 daily trips between Phoenix, AZ and Florence, SC. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Phoenix, AZ to Florence, SC?

Prices and availability for 2 trips between Phoenix, AZ and Florence, SC change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Phoenix, AZ to Florence, SC

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Phoenix, AZ and to Florence, SC

Here’s an overview of the most popular bus routes to Phoenix, AZ and to Florence, SC. Simply click on the connection of your choice, and you will find all the details about your bus route!
Bus from Madera, CA to Phoenix, AZ Bus from Madera, CA to Phoenix, AZ
From Victoria, TX to Phoenix, AZ bus From Victoria, TX to Phoenix, AZ bus
Baldwin Park, CA to Phoenix, AZ bus Baldwin Park, CA to Phoenix, AZ bus
Bus Las Cruces, NM to Phoenix, AZ Bus Las Cruces, NM to Phoenix, AZ
Buses to Florence, SC from Ciudad Altamirano Buses to Florence, SC from Ciudad Altamirano
Bus from Bangor, ME to Florence, SC Bus from Bangor, ME to Florence, SC
Bus Jackson, MI to Florence, SC Bus Jackson, MI to Florence, SC
Bus from Cherry Hill, NJ to Florence, SC Bus from Cherry Hill, NJ to Florence, SC
Popular Airport Shuttles to Phoenix, AZ and to Florence, SC
CheckMyBus › Buses in USA › Bus to Phoenix, AZ › Bus to Florence, SC

The CheckMyBus App

Free Download

App Store
CheckMyBus App
Close
GPDR CheckMyBus shield

We value your privacy!

To

show

you

the

best

bus

offers,

we

and

our

partners

use

technical,

analytical,

and

marketing

cookies

to

personalize

the

ads.

We

remember

your

anonymized

details

to

provide

a

personalized

experience.