Bus from Durham, NC to Florence, SC from $37

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Compare all timetables for the bus from Durham, NC to Florence, SC

Here is a selection of the cheapest bus trips from the schedule from Durham, NC to Florence, SC from various bus operators like Wanda Coach or FlixBus for the next days.
today
tomorrow
from $60
Saturday
from $60
Sunday
Monday
from $51
Tuesday
from $37
Wednesday
from $60

Cheapest bus trips tomorrow

Prices are for one way and one person
  • Wanda Coach
    3h 40m
    0
    4:20 AM
    Durham, NC
    BP Hillandale Rd
    8:00 AM
    Florence, SC
    Shell Gas Station
    0
    Wanda Coach
    Economy
    $60
  • Wanda Coach
    3h 40m
    0
    4:20 AM
    Durham, NC
    BP Guess Road
    8:00 AM
    Florence, SC
    Exxon Gas Station
    0
    Wanda Coach
    Economy
    $60

Cheapest bus trips Saturday

Prices are for one way and one person
  • Wanda Coach
    3h 40m
    0
    4:20 AM
    Durham, NC
    BP Hillandale Rd
    8:00 AM
    Florence, SC
    Shell Gas Station
    0
    Wanda Coach
    Economy
    $60
  • FlixBus
    8h 25m
    0
    9:10 PM
    Durham, NC
    Exxon
    5:35 AM
    Florence, SC
    TA Travel Center
    0
    FlixBus
    Economy
    $68

Cheapest bus trips Monday

Prices are for one way and one person
  • FlixBus
    8h 15m
    0
    9:15 PM
    Durham, NC
    Exxon
    5:30 AM
    Florence, SC
    TA Travel Center
    0
    FlixBus
    Economy
    $51
  • Wanda Coach
    3h 40m
    0
    4:20 AM
    Durham, NC
    BP Guess Road
    8:00 AM
    Florence, SC
    Exxon Gas Station
    0
    Wanda Coach
    Economy
    $60
  • Wanda Coach
    3h 40m
    0
    4:20 AM
    Durham, NC
    BP Hillandale Rd
    8:00 AM
    Florence, SC
    Shell Gas Station
    0
    Wanda Coach
    Economy
    $60

Cheapest bus trips Tuesday

Prices are for one way and one person
  • FlixBus
    8h 15m
    0
    9:15 PM
    Durham, NC
    Exxon
    5:30 AM
    Florence, SC
    TA Travel Center
    0
    FlixBus
    Economy
    $37
  • Wanda Coach
    3h 40m
    0
    4:20 AM
    Durham, NC
    BP Hillandale Rd
    8:00 AM
    Florence, SC
    Shell Gas Station
    0
    Wanda Coach
    Economy
    $60

Cheapest bus trips Wednesday

Prices are for one way and one person
  • Wanda Coach
    3h 40m
    0
    4:20 AM
    Durham, NC
    BP Guess Road
    8:00 AM
    Florence, SC
    Exxon Gas Station
    0
    Wanda Coach
    Economy
    $60

Frequency of bus connections between Durham, NC and Florence, SC

See here how frequent the connections between Durham, NC and Florence, SC are, during different times and days of the week.
Monday is the busiest day, with more than 3 daily buses from Durham, NC to Florence, SC. Wednesday has instead the fewest connections, with only 1 daily coaches between Durham, NC and Florence, SC.
The busiest time of the day is the Night, with 7 buses from Durham, NC to Florence, SC, while Evening sees the fewest connections between Durham, NC and Florence, SC, with 3 offers.

Facts about the bus from Durham, NC to Florence, SC

Compare all providers like Wanda Coach and FlixBus that travel 2 times every day by bus from Durham, NC to Florence, SC in one click! Book your bus ticket from Durham, NC to Florence, SC starting from $37!

Cheapest Bus $37
Fastest Bus 3h 40m
Earliest Bus 4:20 AM
Latest Bus 4:20 AM
Daily Bus Routes 2 Ø
Distance 133.6 miles
Bus Companies Wanda Coach and FlixBus

Cheapest bus connections from Durham, NC to Florence, SC

Every day, 2 buses from 2 bus companies leave Durham, NC for Florence, SC: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 06/19/2025 and for the following days.

Sunday
Monday
Tuesday
Wednesday
Thursday
Friday
Saturday
Sunday 06/15
Monday 06/16
Tuesday 06/17
Wednesday 06/18
Thursday 06/19
Friday 06/20
$60
Saturday 06/21
$60
Sunday 06/22
Monday 06/23
$60
Tuesday 06/24
$37
Wednesday 06/25
$60
Thursday 06/26
$60
Friday 06/27
$60
Saturday 06/28
Sunday 06/29
Monday 06/30
Tuesday 07/01
Wednesday 07/02
Thursday 07/03
Friday 07/04
Saturday 07/05
Sunday 07/06
Monday 07/07
Tuesday 07/08
Wednesday 07/09
Thursday 07/10
Friday 07/11
Saturday 07/12

The cheapest time to travel from Durham, NC to Florence, SC

See here on which day and which time of the day you can find the cheapest bus ticket from Durham, NC to Florence, SC, for the next 30 days.
With a price starting from $37, Tuesday is the cheapest day for a bus from Durham, NC to Florence, SC. Saturday instead is the most expensive day with prices starting from $60.
Evening is the cheapest day time for bus tickets from Durham, NC to Florence, SC, with $37. Night is the most expensive time of the day with prices starting from $59.

How to save money travelling from Durham, NC to Florence, SC

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Durham, NC to Florence, SC in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Durham, NC to Florence, SC, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Durham, NC to Florence, SC are also emptier.

Beloved bus companies from Durham, NC to Florence, SC

These are the most booked bus companies between Durham, NC to Florence, SC from our users.

FlixBus from Durham, NC to Florence, SC

FlixBus

Here you will find the key facts about the FlixBus bus route Durham, NC to Florence, SC:

Cheapest Price $37
Fastest Bus 8h 15m
Earliest Bus 9:10 PM
Last Bus 9:15 PM
Daily Connections 1 Ø
Found on 6/16/2025

All bus stations and stops in Durham, NC and Florence, SC

In the map below, you can see where to find all bus stations in Durham, NC and Florence, SC.

Service and Comfort on the bus from Durham, NC to Florence, SC

Want to know which seat classes are available on the buses from Durham, NC to Florence, SC? Or which bus companies serve the route Durham, NC to Florence, SC? Below you will find answers to your questions.

FAQs about the Durham, NC to Florence, SC bus

How much does a Durham, NC Florence, SC bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $37 and takes 8h 15m to reach Florence, SC. Compare offers to save money!

How much could I save by comparing buses from Durham, NC to Florence, SC?

This route is offered by 2 companies with a range of ticket prices between $37 and $68. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Florence, SC.

On average, how many connections are available from Durham, NC to Florence, SC each day?

Every day, the Durham, NC to Florence, SC bus route is served by approximately 2 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Durham, NC to Florence, SC take?

The fastest bus from Durham, NC to Florence, SC is offered by Wanda Coach and takes 3h 40m. Bus tickets for this connection cost $60. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Durham, NC to Florence, SC?

The earliest bus arriving in Florence, SC from Durham, NC starts at 4:20 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Durham, NC to Florence, SC?

The latest bus trip departing from Durham, NC for Florence, SC starts at 4:20 AM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Durham, NC Florence, SC route?

When traveling by bus from Durham, NC to Florence, SC, passengers can travel with Wanda Coach and FlixBus. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Durham, NC and Florence, SC?

You can check all the direct connections between Durham, NC and Florence, SC by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Wanda Coach and FlixBus.

What can I take with me on the Durham, NC to Florence, SC bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Durham, NC Florence, SC bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Durham, NC Florence, SC bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Durham, NC to Florence, SC on your planned travel date.

Available seat classes which are offered on the bus route Durham, NC to Florence, SC

Economy
Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Durham, NC and to Florence, SC

Here’s an overview of the most popular bus routes to Durham, NC and to Florence, SC. Simply click on the connection of your choice, and you will find all the details about your bus route!
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Popular Airport Shuttles to Durham, NC and to Florence, SC
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