Bus Jackson, MI to Florence, SC: Compare prices and save money

Compare all timetables for the bus from Jackson, MI to Florence, SC

Here is a selection of the cheapest bus trips from the schedule from Jackson, MI to Florence, SC from various bus operators like Greyhound US for the next days.

today

tomorrow

$219

Tuesday

Wednesday

Thursday

$104

Friday

$104

Saturday

Cheapest bus trips tomorrow
Mode of Transport	BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Logo	Seat classes	Price
	Greyhound US	31h 40m	1:30 AM	Jackson, MI	Bus Stop	9:10 AM	Florence, SC	Bus Station		Economy	$219	A Bus from Greyhound US goes from Bus Stop, Jackson, MI (USA) at 7/20/2026 1:30:00 AM to Bus Station, Florence, SC (USA) arriving at 7/21/2026 9:10:00 AM. 50 Economy ticket for $219 per person are available. Travel duration is 31h 40m
	Greyhound US	41h 5m	12:40 PM	Jackson, MI	Bus Stop	5:45 AM	Florence, SC	TA Travel Center		Economy	$244	A Bus from Greyhound US goes from Bus Stop, Jackson, MI (USA) at 7/20/2026 12:40:00 PM to TA Travel Center, Florence, SC (USA) arriving at 7/22/2026 5:45:00 AM. 50 Economy ticket for $244 per person are available. Travel duration is 41h 5m

Did you know that if you travel from Jackson, MI to Florence, SC via Indianapolis, you can save more than $80? You can find the corresponding connections below.
- Greyhound US
  
  36h 0m
  
  0
  
  1:30 AM
  
  Jackson, MI
  Bus Stop
  
  11:50 AM
  
  Indianapolis
  Washington / Delaware
  
  0
  
  Economy
  
  $55
  
  A Bus from Greyhound US goes from Bus Stop, Jackson, MI (USA) at 7/20/2026 1:30:00 AM to Washington / Delaware, Indianapolis (USA) arriving at 7/20/2026 11:50:00 AM. 50 Economy ticket for $55 per person are available. Travel duration is 10h 20m
- FlixBus
  
  18h 55m
  
  0
  
  6:35 PM
  
  Indianapolis
  Downtown Transit Center
  
  1:30 PM
  
  Florence, SC
  Bus Station
  
  0
  
  Economy
  
  $83
  
  A Bus from FlixBus goes from Downtown Transit Center, Indianapolis (USA) at 7/20/2026 6:35:00 PM to Bus Station, Florence, SC (USA) arriving at 7/21/2026 1:30:00 PM. 50 Economy ticket for $83 per person are available. Travel duration is 18h 55m
Travel time is 4h 20m longer, but you will save $80

Cheapest bus trips Thursday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	27h 5m	12:40 PM	Jackson, MI	Bus Stop	3:45 PM	Florence, SC	Bus Station	Economy	$104	A Bus from Greyhound US goes from Bus Stop, Jackson, MI (USA) at 7/23/2026 12:40:00 PM to Bus Station, Florence, SC (USA) arriving at 7/24/2026 3:45:00 PM. 50 Economy ticket for $104 per person are available. Travel duration is 27h 5m
Greyhound US	35h 25m	12:40 PM	Jackson, MI	Bus Stop	12:05 AM	Florence, SC	TA Travel Center	Economy	$130	A Bus from Greyhound US goes from Bus Stop, Jackson, MI (USA) at 7/23/2026 12:40:00 PM to TA Travel Center, Florence, SC (USA) arriving at 7/25/2026 12:05:00 AM. 50 Economy ticket for $130 per person are available. Travel duration is 35h 25m
Greyhound US	31h 40m	1:30 AM	Jackson, MI	Bus Stop	9:10 AM	Florence, SC	Bus Station	Economy	$219	A Bus from Greyhound US goes from Bus Stop, Jackson, MI (USA) at 7/23/2026 1:30:00 AM to Bus Station, Florence, SC (USA) arriving at 7/24/2026 9:10:00 AM. 50 Economy ticket for $219 per person are available. Travel duration is 31h 40m

Cheapest bus trips Friday
BertCompanyCountOneCompanyName	Duration	Departure time	From	Departure	Arrival time	To	Destination	Seat classes	Price
Greyhound US	27h 5m	12:40 PM	Jackson, MI	Bus Stop	3:45 PM	Florence, SC	Bus Station	Economy	$104	A Bus from Greyhound US goes from Bus Stop, Jackson, MI (USA) at 7/24/2026 12:40:00 PM to Bus Station, Florence, SC (USA) arriving at 7/25/2026 3:45:00 PM. 50 Economy ticket for $104 per person are available. Travel duration is 27h 5m
Greyhound US	27h 15m	10:15 AM	Jackson, MI	Bus Stop	1:30 PM	Florence, SC	Bus Station	Economy	$130	A Bus from Greyhound US goes from Bus Stop, Jackson, MI (USA) at 7/24/2026 10:15:00 AM to Bus Station, Florence, SC (USA) arriving at 7/25/2026 1:30:00 PM. 50 Economy ticket for $130 per person are available. Travel duration is 27h 15m
Greyhound US	35h 25m	12:40 PM	Jackson, MI	Bus Stop	12:05 AM	Florence, SC	TA Travel Center	Economy	$139	A Bus from Greyhound US goes from Bus Stop, Jackson, MI (USA) at 7/24/2026 12:40:00 PM to TA Travel Center, Florence, SC (USA) arriving at 7/26/2026 12:05:00 AM. 50 Economy ticket for $139 per person are available. Travel duration is 35h 25m
Greyhound US	31h 40m	1:30 AM	Jackson, MI	Bus Stop	9:10 AM	Florence, SC	Bus Station	Economy	$218	A Bus from Greyhound US goes from Bus Stop, Jackson, MI (USA) at 7/24/2026 1:30:00 AM to Bus Station, Florence, SC (USA) arriving at 7/25/2026 9:10:00 AM. 50 Economy ticket for $218 per person are available. Travel duration is 31h 40m

Best Price Offer: The price for the cheapest bus from Jackson, MI to Florence, SC is $104 on 7/23/2026. Flexible travelers save on ticket prices.

Frequency of bus connections between Jackson, MI and Florence, SC

See here how frequent the connections between Jackson, MI and Florence, SC are, during different times and days of the week.

Friday is the busiest day, with more than 4 daily buses from Jackson, MI to Florence, SC. Monday has instead the fewest connections, with only 2 daily coaches between Jackson, MI and Florence, SC.

The busiest time of the day is the Afternoon, with 5 buses from Jackson, MI to Florence, SC, while Morning sees the fewest connections between Jackson, MI and Florence, SC, with 1 offers.

Facts about the bus from Jackson, MI to Florence, SC

Compare all providers like Greyhound US that travel 3 times every day by bus from Jackson, MI to Florence, SC in one click! Book your bus ticket from Jackson, MI to Florence, SC starting from $104!

Cheapest Bus	$104
Fastest Bus	27h 5m
Earliest Bus	1:30 AM
Latest Bus	12:40 PM
Daily Bus Routes	3 Ø
Distance	610.5 miles
Bus Companies	Greyhound US

Cheapest bus connections from Jackson, MI to Florence, SC

Every day, 3 buses from 1 bus companies leave Jackson, MI for Florence, SC: in the table below, you will find the cheapest prices for a bus ticket for this route, starting from 07/19/2026 and for the following days.

Sunday

Monday

Tuesday

Wednesday

Thursday

Friday

Saturday

Sunday 07/19

Monday 07/20

$219

Tuesday 07/21

Wednesday 07/22

Thursday 07/23

$104

Friday 07/24

$104

Saturday 07/25

Sunday 07/26

Monday 07/27

Tuesday 07/28

$134

Wednesday 07/29

Thursday 07/30

Friday 07/31

$104

Saturday 08/01

$143

Sunday 08/02

$148

Monday 08/03

$237

Tuesday 08/04

$132

Wednesday 08/05

Thursday 08/06

Friday 08/07

$130

Saturday 08/08

Sunday 08/09

$130

Monday 08/10

$232

Tuesday 08/11

$132

Wednesday 08/12

Thursday 08/13

Friday 08/14

Saturday 08/15

The cheapest time to travel from Jackson, MI to Florence, SC

See here on which day and which time of the day you can find the cheapest bus ticket from Jackson, MI to Florence, SC, for the next 30 days.

With a price starting from $104, Thursday is the cheapest day for a bus from Jackson, MI to Florence, SC. Monday instead is the most expensive day with prices starting from $219.

Afternoon is the cheapest day time for bus tickets from Jackson, MI to Florence, SC, with $104. Morning is the most expensive time of the day with prices starting from $129.

How to save money travelling from Jackson, MI to Florence, SC

Travel can be expensive, but it doesn't need to be! Do you want to avoid paying a terrible price for your trip? Then follow these quick steps to save money:

Book the ticket from Jackson, MI to Florence, SC in advance! The earlier you book, the cheaper usually the price is. Also, you will be sure to have a place on the bus from Jackson, MI to Florence, SC, compared instead if you buy it at the last moment, or directly at the station.

If you can, avoid travelling at peak times. Instead of weekend, try travelling during the week. Travelling in the evening or at night it’s also cheaper, and later buses from Jackson, MI to Florence, SC are also emptier.

All bus stations and stops in Jackson, MI and Florence, SC

In the map below, you can see where to find all bus stations in Jackson, MI and Florence, SC.

Bus Stop

W Cortland St 127

Bus Station

S Irby St 611

TA Travel Center

W Lucas St 2301

Exxon Gas Station

W Lucas Street 1901

McDonalds

W. Lucas St. 1908

Shell Gas Station

W Lucas Street 1832

Service and Comfort on the bus from Jackson, MI to Florence, SC

Want to know which seat classes are available on the buses from Jackson, MI to Florence, SC? Or which bus companies serve the route Jackson, MI to Florence, SC? Below you will find answers to your questions.

FAQs about the Jackson, MI to Florence, SC bus

How much does a Jackson, MI Florence, SC bus trip cost?

This depends on, among other things, the day and time of travel. The cheapest trip is available from $104 and takes 27h 5m to reach Florence, SC. Compare offers to save money!

How much could I save by comparing buses from Jackson, MI to Florence, SC?

This route is offered by 1 companies with a range of ticket prices between $104 and $244. Thus, we recommend booking your ticket as early as possible to make sure you get the cheapest bus ticket to Florence, SC.

On average, how many connections are available from Jackson, MI to Florence, SC each day?

Every day, the Jackson, MI to Florence, SC bus route is served by approximately 3 connections. With our search, you can compare bus times to find the perfect trip.

How long does a bus journey from Jackson, MI to Florence, SC take?

The fastest bus from Jackson, MI to Florence, SC is offered by Greyhound US and takes 27h 5m. Bus tickets for this connection cost $104. In this context, bear in mind that the journey can take longer due to traffic.

What time is the first bus from Jackson, MI to Florence, SC?

The earliest bus arriving in Florence, SC from Jackson, MI starts at 1:30 AM. However, information regarding departure times may differ on weekends and holidays. Simply use our search to find exact times for your planned travel date.

What time is the last bus from Jackson, MI to Florence, SC?

The latest bus trip departing from Jackson, MI for Florence, SC starts at 12:40 PM. Please note that departure times may differ on weekends and holidays. So just use our search to find the exact times for your planned travel date.

Which bus companies operate the Jackson, MI Florence, SC route?

When traveling by bus from Jackson, MI to Florence, SC, passengers can travel with Greyhound US. With our search, you can compare all available bus tickets to book the one that works for you.

Is there a direct bus between Jackson, MI and Florence, SC?

You can check all the direct connections between Jackson, MI and Florence, SC by using our search and looking at the Changes section in our filters. These are some of the companies which offer a direct bus: Greyhound US.

What can I take with me on the Jackson, MI to Florence, SC bus route?

Depending on which provider you travel with, what you're allowed to bring with you can vary. Generally, you can take a suitcase and hand luggage with you on the Jackson, MI Florence, SC bus route free of charge. Simply use our search to find a bus that is best suited to your needs for your planned travel date.

What equipment is available for the Jackson, MI Florence, SC bus route?

The equipment on board differs depending on the provider. However, many long-distance buses have WiFi so you can tell your friends your exact location during the journey. To make traveling even more pleasant, air conditioning systems provide ventilation. It is best to use our search to get precise information about the equipment of the bus from Jackson, MI to Florence, SC on your planned travel date.

How does CheckMyBus find the best bus deals from Jackson, MI to Florence, SC?

CheckMyBus collaborates directly with companies around the world to provide you with the best options when searching for a trip. We retrieve their first-hand data to show you real-time prices, schedules, and seat availability for 3 daily trips between Jackson, MI and Florence, SC. With the most up-to-date information from verified sources, you can fairly compare all available options and choose the trip that suits you best.

How does CheckMyBus technology work for trips from Jackson, MI to Florence, SC?

Prices and availability for 3 trips between Jackson, MI and Florence, SC change constantly. To provide you with the most up-to-date information, we connect directly with bus operators, Online Travel Agencies (OTAs), and Global Distribution Systems (GDS) via real-time interfaces (APIs). The data collected from these sources undergoes strict quality checks, is processed within our infrastructure, and is then presented to you on our search results pages. Visit our About Us page to learn more.

Available seat classes which are offered on the bus route Jackson, MI to Florence, SC

Economy

The cheapest option available for your ticket, it usually comes with reclinable seats and AC.

More bus routes to Jackson, MI and to Florence, SC

Here’s an overview of the most popular bus routes to Jackson, MI and to Florence, SC. Simply click on the connection of your choice, and you will find all the details about your bus route!